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# Anabaena variabilis ATCC 29413, ATCC 29413

>Ava_0633 Bacitracin resistance protein BacA
MTLFKRQWFVLVSAVSAALSVVLFPLEVFSASPNSVGGGVQQMNILQAIV
LGFVQGMTEFLPISSTAHLKVVPVALGWGDPGVAFTAIIQLGSIAAVLWY
FWGDLTRIIKGATRAIALKDYADYDLRLSLGIILGTIPIVFFGLLIKKLI
PDFDSSPIRSLGAIAVASIVMSLLLGVGEKLGKRERDFEHLTMQDGLLMG
LAQALALIPGVSRSGSTLTSGLFMGLQRETAARFSFLLGIPAITLAGLVE
LKDVFAEGIADGAALPLIVGVISAAIFSYMAIAGLLSFLKTQSTWVFIWY
RLVFGIAILGAISAGILQNS
>Ava_4150 ABC-2
MISTIIQIFTKTFVIAEMEVRKLRHDPTDLIVRAVQPSLWLLIFGQVFSR
IRAIPTGELPYLDFMTAGILAQSVLFVAIFTGGMTLIWERDLGVVHKFLA
SPTPRVAMVLGKSLACGVRCLSQVLVIYVLALILGVNLNLHPLAFIQVLF
VVMLGAGCFCTFSLIIGCLVKTRERMTGIGQLLTMPLFFASNAIYPISMM
PDWLKFLSRVNPLTYQVDGLRGTMLANGTSIYGFGWDCAILLLTLIGLTL
ICGRLYPRVAM
>Ava_4995 ABC transporter, transmembrane region
MAKFKDIVNYFRDDWKLSAFTIAASSVYEIVDLLVPYAIGQILNVLSNQP
LDKPLEGAIATLSQLTNYPVSKPLSLGVLMGLIFLVTVVRAPTQPWLTSW
FHWDIALRSRRNKTQSAIEKILTLPLEFYDVNNPGRIAGRVARGISNHTW
TYPEIAGQLIPKLFRVLGIFVFIILIEWRIAILYLISFVIILGFSLKQLQ
RIIWHESLLDKYAENTESRTSELITNIKTVKAFATESKELKRQKQRLDRE
LKVVDYRIHKGYVNLLTWQKTVIQFCVFSILGLTLAATVSGRVSLGHFVM
TLTLSSMAYSELEPISTLAEVFARRYSSMLRFHEFLQEPTGYDAASLLEK
DDTSSPYKFTGKVEFSRISFGYDASRKVLQDINLLIEPYQTVALVGRSGS
GKSTLVKLLLRYFEPQDGQILIDGQDIRTLNVGKYRRRLAIVHQEVDVFN
GTVLDNLTYGRPEATFEQVKEACRIARVDEVMQQLPQGYYTVVGERGVRL
SGGQRQRLGIARALLVEPDVLIFDEATSSLDYESERAIQLAMRSIQGTCT
TIVIAHRLSTVREADKIVVLDQGKIVEVGNHDELLRQEGIYRRLHSLQET
GELLD
>Ava_4342 ABC transporter, transmembrane region
MSIYQLSQKSYKQNRWRNNDWRLFSRLVPYARRNTKLLILAMVLLLPLAL
ANAVQPLLIGQAVSLIRNESSAYEFLRSRPLSQGLHIIEGILLFTIVIRL
ALTGYQGYLLQKLGQKITAAIRQDLFHHVTSLAVRFFDRTPVGKLITRLT
SDVEVLGDVFSTGAIGIVSDVVLMVVITGLMFSIQWQLASLLLVMLLPVT
WLIIYFQQEYRKANYKAREELSLLNSQLQENVLGINVVQLFRRESFNAEL
FRTTNQRYTKQVDQTIFFDSAVSATLEWIGLIAIAGVLWVGGWLLSENQL
DFGTLSTFILYAQRLFDPLRDFAEKFTVIQSGFTAIERVSDILDEPIEIS
DRSNSRFSVFDAKFGYIDEIVADLESQNISDTPNMGEIRFEHVWFAYKDD
DYVIKDLDFIIRPGEKVALVGPTGAGKSSIIRLLCRLYEPTQGRILVDGI
DIRELPQAELRRYMAVILQEGFLFAGNVKSNITLGDYYTFEEIQAAAQQT
NIAEFIEELPLGYDTKLRERGTNLSSGQKQLLAFARAAIRNPQILVLDEA
TASLDVGTEALVQEALNELLIGRTAIIIAHRLSTIRNVDRIFVLKRGELV
EQGSHEELLNSGGLYSTLHNLQMLGT
>Ava_4939 AmpD
MNFRDWATRVTLIFLMLAALILALLAGKSTQLQQNTATPSNSDIATWRQY
PQIQIQSGINQGSKAQDIGNFPVITNQSSDRYITTQAFAEYKPKLEIAAV
HPSNYGERYAQDINGLPIKNQPIIVLHETSNSATSAVNFFQTPHTDENVQ
ASYHAIIKLDGTVLYLVPPEKRAFGAANSVFDGADGIETVQTNPKLPPSV
NNFAYHVSLETPPDGRGNNFLKSHSGYTPEQYNSLAWLIAQSQVPEDRIT
THKAVDRSSQRVDPLSFDFDKFLELLNTYRQVSPVYRAQK
>Ava_2125 Type III restriction enzyme, res subunit
MVYVSLDLEQLREQDTNFVPKSPFQHQIEAFEKLSNTFRLDNKKPGSGIL
VLPTGAGKTFTAVRWLCDHVVPKNIKILWLAPSYYLLDQAFSTFKENARG
ISYSKKILNIRCVSSNPSHAKAASIKSTDDIIIMTVQTAISNLSPNALDG
SGNKVKTPFRKFIENCKETGLFIIVDEAHHSPAYGCRNLLIGEIGLRSIV
PNSNILGLTATPTYTDKTRRGWLWKIYKDGVNGVIYQADKEALIAQDILA
RPNYIEVSTGTEMVVDDRLYEKLVKQHKDLPESIIETLANDKHRNNLIVK
TYTSNKDIYGKTIIFADRWFQCVYIKDKLLEKGIKADAIYSHIDADPGSS
EARNKRREDENKTILDEFRNNKLDVLINVRMLTEGADIPNVQSVFITRQT
TSSILMTQMIGRALRGKKIKGNSEANVVLFFDDWKRLIDWATPQIGDTKD
TGKESTIKSYPLEYISIRLVEELSKSIESGGVHEVIFSKIFPIGWYKTEI
VYADSDKNNESIEAFTEYVMVYDHTQSKLNKFINFILDFKLPVEWSKEYL
NDESLEQQIGEWIDSWFDWKTDNLGDKLSADLIKIVRHIAQNQSAPEYYS
FDERENYDLDRIAKRLIDFSPREIDKYINEEFAKPGTLWKTFYKTPNRLI
TSVHLAIIKIIHGGDSEIPTITVISPSPHKDRELSEKEKVKVKKRDSYTC
LCCGANTEAKLQVDHIKPFSMGGETSIQNSQTLCNICNKCKGKNEIDFRC
NTTKLAIPKNLDLTFRTESQHSIRTLTRVVNLFYHCKAIYKIEWDSTIRG
YIIYLYPGNNPQWLLQHKAQLLEYIQDKLGRQAYNIVVTTKE
>Ava_A0005 hypothetical protein
MVKYRFSLKVKGEDSEYSYFLDLTPNQENMPQQVFSSQIREDIRLNLQNQ
TLCAIKDFHLNQIINTWIQDIKEGYRDSTLTLQLPLLIEAGIAQINEQGN
QENPHVVNPDLSNIEPVWGMLPPLNFS
>Ava_0412 Penicillin-binding protein, transpeptidase
MSQNRRNSLAIIVAITTFVIFLTTSNFPGMPGHSQEIQTPAIPVSVNLGR
SFNQLGIKGSILIYDRNNKKFYEHNTARNSQSFLPASTFKIFNSLVALET
GVISNDVAILTWDGIQRQFPTWNQDTNIRQAFRNSTVWFYQVLARKIGYE
RMEKFIKQVGYGNLQIGTPEQIDRFWLEGPLQITPKQQIEFLQRLHRKEL
PFSQRTLDLVQDIMIYERTPNYILRGKTGWAASVTPNIGWFVGYLEQNNN
VYFFATNIDIRNNDDAAARIEVTRRSLKALGLL
>Ava_2092 Penicillin-binding protein, transpeptidase
MKSPFLLLGLVSTILLSTPANAARLESWKFDPNRNQLNITTDSEVKPRAF
LINNPDRIVIDLPGTTFKANTQRKNFGAAVREIRIGKVENNTARIVVELA
PGYTTSPDKLVIKGDSASHWILNFSAIKKDADNTETSEEKISIPVSNNLE
FAGVVPLSREISQLDSQIKQLMNRYSSLSAGMFFLDMETGEYLDINGEKT
FAAASTIKFPILIALFEEIDAGRINPNETLVMRRDLMTGGSGTMQYRKAG
SKFKLMETASKMMIISDNTATNMIIDRLGGKNRLNQRFRSWGLQNTVIRN
LLGDFKGTNKTSPKDLVRLAALISNNKLLSATSNSRVMDIMSRCKNRSLL
PVGLGKGAVIAHKTGTLGRVLGDAGIIQTPSGKRYLAGIMVARPFGDARA
KAFINQVSRLVYGYLDQPTSARNF
>Ava_1520 Beta-lactamase
MTLPSPNKVDELFSEWDKPGSPGFALAITKDGETVYKRGYGIADLEHNIK
IFPNSVFDIASTSKQFTAMCIALLARKGKLSLDDEIQIYISEIPRYEYPI
TVRHLIHHTSGIRDYLTLMGLAGMQCENDYPDNEIIGLIARQKELNFKPG
EEHLYSNSGYFLLAEIVKRVSGESLAVFADKHIFSPLGMKTTHFHDDFTR
IVRNRAIGYSVRDEGSFRIDMSILDVVGDGGIYTTVEDLCIWDQNFYQNK
LGGYGQDLIEEIITPGRLNSGEVIDYAFGLVIGHYRGLETISHSGGWMGY
RSQMLRFPKQRFSVICLSNLGSAEPPELARKVADIYLVDDFTEQSIESVS
RQTQIREIPSVDLESKTGFYQNLKTGTVWELLVKDGKLIVEFAGMSFTLA
PVSSSHFVIMDIPSNPDVEFEESGLDEPSHLYVCVDGKPREVFQRLDFAP
PDSEQLMDFTGEYYCQELDVTYRITIEDGELLLNRRNSLRETLKPINKDL
LEGTDITLQFVRDDFHQAVGFNMSAGYGSVRNIQFVK
>Ava_1158 Restriction modification system DNA specificity domain
MMKRKTPTIDEHLHEFKISNKTDESYKNRDFGFVPESWKIVKFENILSIF
NGYAFKSTDAVDSSNTQLIRMGNLYQNKLDLERSPVFYPDYYAQKYSKYL
LKEGDLIISLTGTSEKEDYGFTVKINRTDKNLLLNQRVARIDVISADINH
DYIFYFLRSRIFLTPLYLTAKGMKQANLSTNTIKTLNVLIPPLEEQRKIA
WILSLVQDAITQQEQIISLTTELKKVLMQKLFTEGTRGEPQKMTEIGFIP
KSWEVIRFADAISVTSGQVNPKEKPYSEMLHVGSENIESNSGRLLCLQTN
QELNISSGNYYFNNDDILYSKIRPYLNKVALPDFEGTCSADMYPIRSKNG
CFNRNFLFHFLLSDIFRNQAISFQDRTGIPKINRAQLGSTLLIRPSLLEQ
NEISYALDLCDKRINTAYQNLSTSKDLFRILLHQLMTAQIRVDDLNLSAL
NLVS
>Ava_2852 ABC transporter-like
MSNTISLTDSLVPHPAPQSAIIRLENIFKVYGIGETEVKALNDVNLVINE
GEYCSIMGPSGSGKSTAMNIIGCLDRPTEGHYYLDGLDVAQMNDKDLAHI
RNRKLGFVFQQFHLLPQLSALENVMLPMVYADVTPNERRDRATEALIRVG
LEKRLNNKPTQLSGGQQQRVAIARAIVNRPVVLLADEPTGALDSRTTQEV
LDIFTELNSGGITVVMVTHEPEVARQTKRIVWFKDGQVVHSHMTPADLTD
GF
>Ava_1159 N-6 DNA methylase
MGERNGNGDKSLENWIWDAACSIRGAQEAAKYKDFILPLIFTKRLCDVFD
DELNRIAEKVGSRAKAFKLVAMDHNLVRFYLPLQPQNPDDPVWSVIRKLS
DKIGEKLTDYLREIAKANPLLNGIINRVDFNATTHGQRDLDDDRLSNLIE
KISEKRLGLKDVEPDIIGRSYEYLIRKFAEGSGQSAGEFYTPKEVGLIMA
KIMQPEPGMTIYDPCCGSAGLLIKCQLVLQESQGATEKFAPLQLYGQEYT
PNTWAMANMNMIIHDMEGKIEIGDTFRHPKFMQAGKLAQFERVVANPMWN
QKWFTEKDYDGDELGRFPKGAGYPGSSADWGWVQHILASLDKTGKAAIVL
DTGAASRGSGNANKNKEKEVRKWFVEQDLIEGVIYLPQNLFYNTSAPGIL
LFLNRAKPKERQGKLFFINASLVFAKGDPKNYIPDEEIERIANTFLTWRE
EEKFSLIVYKDKIAHNDYNISPSRYIHITEEEDFRPIAEILEELEVLEKE
AAETNKLLMKVLGRYQ
>Ava_C0223 conserved hypothetical protein
MAIDPEITRHKEWLGFLQPVGLVVSPPALVKAQAVVNRNVVDFQQSLLAA
VDEDGLIADFPAFTVNVLGWAESDLVKPSAEYEIALPDYSEILAPTYIVP
DPDSDKPQILVQIISPGTELDVVAPELTKSSSGWHASPQAKFERLLRETQ
IPIGLLCNGGLLRLVYAPRGESSGHLTFPVQAMCEVSGRLILGAMEMLLS
AFRVFSATTGRSLKNLLEDSRKYQAEVSTTLANQVLDALWELLRGFQMAD
AAVDGKLLSEIAATDPQHIYGGLITTLMRLVFLLYAEDEGLMPPDDIYQR
NYSVTGLYERLREDAGNYPDTMDQRYGAWVWLLSLFRLVYDGGGQTPEYL
PARHGQLFDPDEYAFLESRPRGSKFVAGQAIEPPRIPDGVIYRLLEKLLI
LEGERLSYRSLDVEQIGSVYEGIMGFAVERAESPSIGVYSKPKGSKVSTT
VVVDVAAILAAKSGDRQKLLKELANCEVSGNALKELKAAQSLEDIAIALG
RKVSRQTPNLLPVGSLYLQPGEERRRSGSHYTPRSLTKPIVETTLRPVLE
ALGEKPTAEQILSLKVCDLAMGSGAFLVETCRQLAEKVVEAWEREENDTR
LGISDHSASQRHPNQNATISNYGKEEPLLIARRLVAQRCLYGVDKNPFAV
NLAKLSLWLVTLAKDLPFTFLDHALKCGDSLVGLRKEQIGSFGKDATDDL
PLFIYLKEQLDRARSYRAEIQALDTRSDADDDQKRDYLYKVEQELYQARL
TGDVRIAAFFEGSNKKQREERETEIAELVRKWRYHQADTESLEEIASRLR
SGDKGIIPFNWDIEFPEVFDRENPGFDAIVGNPPFLGGKRISTVLGDAYK
DWLPVVNPESNSNADLVAHFFRRAFDLLRQGGTFGLVATNTIAQGDTRSS
GLRYICQNQGTIYNAQKRMKWPGQAAVVVSVVYVLKGTYKGIYLLNGREV
SLISAFLFHVGTNENPAVLLANSNKSFIGSYVLGMGFTFDDTNDEATPIT
EMHRLIEKDGRNAERIFPYIGGEEVNSSPTHAHRRYVINFGEMSEDEARK
WSDLIEIVEIKVKPHRDTLKRDAYRKRWWHFAEKQAALYRAIAPLEKVLV
VSRHQPNWSAAFMGANVVFSEGLVVLALSQYSSFALLQSRIHEIWVRFFG
SSLEDRLRYTPTDCFETFPFPQNWETNPTLEAIGQEYYEYRAALMVRNNQ
GLTDTYNRFHDPEERDADILKLRSLHAAMDKAVLEAYGWSDIPTDCTFLL
DYDDEEDEEETSNGRQRKKPWRYRWTEEVHDEVLARLLDLNQKRAQAEIL
GGKAAQKKPKPKATKKKTTKTKSKKVGETTPIIPGFDVETGL
>Ava_1233 DevC protein
MTGFIQELQRRTPLGWLQLSHYKSRLLVALSGIAFADVLMFMQLGFQNAL
YDSNTRLNRAVLADIVLISPQSRNMQNLATFSRRRLLQAADVPGVKSAEA
MYIGLVTWKNPQTRRKTSVQAIGFNPEQPALNIPEVNNQLDKIKLPDNFI
FDRAARGEYNKVFSQISAGESVTTEVDKRTISISGTFKLGASFGADGTLI
SSDENFLRLFPRRLAGSINLGLVNVQPGYDPKQVAEALKSYLPNDDVKVL
TRAEYVKMEEDYWKTSSPIGFIFSLGVSMGFMVGVIIVYQVLSTDVNAHL
KEYATFKAMGYGNSYLLGVIFEEALILAVLGFIPGFIVPLGLYRLAANAT
NLPIFMTAVRAFLVLLLTLIMCIFSGAIATRKLQSADPADMF
>Ava_2251 ABC transporter-like
MLPAIAISHLNHYYGEGSLKKQILFDINLTIQPGEIVIMTGPSGSGKTTL
LTLIGSLRSVQSGSLEILGKELSGATKNEMVEVRRNIGYIFQAHNLLGFL
TAQQNVQMPFEMNQSISFRAATTKAAEMLTTVGLGEKLNYYPDDLSGGQK
QRVAIARALVHHPKLVLADEPTAALDSKSGRDVVNLMQKLAKEQGCTILL
VTHDNRILDIADRIIHMEDGYLHQN
>Ava_4460 HNH endonuclease
MAITIPVLEQSVVVFSQNYLPLCRVNIKRAIVLLLTNKAEPLVGYTENGW
RVHSPSLIIDVPKHIRLKITSIERTWKVPPVNRREILRRDHHSCQYCGSR
KRLTLDHVIPRSRGGSHTWDNVVTACERCNSRKGDRTPAEVGMQLRTKPK
PPVHPAVAFAVSDTWRDNATQFWIDMQANLE
>Ava_1617 ABC transporter-like
MPTQVVQAKPATNAFLDFIQFWKDVRAIAGPYWYPTKPGERAFSDVIRAW
GMLILLILSILALVGVTTFNTFIHRYLIDVIIQERNYPKFVDTILIYGVG
LVFITLLVGFTKFIRKQISLDWYQWLNNHILNKYLHNRAYYKINFVPEID
NPDQRLSQEIEPITSSALSFSATFLEKILEMITFLLVVWSISQQIAIALL
IYTFIGNFIAVYLNQELIKINQAELESKADYSYSLTHVRNHAESVAFFQG
EDQEQNIIQRRFTTLINDMKHKINWERNQAIFNRGYRSAIELLTLLVLSP
LYIRGDIDFGQVGQATTACYFFAGALEELIAEFGISGRFSSYVQRLSEFS
DALQAVAKPPENVGTIKTIEENHFAFENVTLQTPNYEQVIVENLSLNVQP
GEGLLIVGPSGRGKSSLLRAIAGLWNAGTGRLMRPPLNEVLFLPQRPYII
LGTLREQLLYPKTHRQMSDAELKEVLQQVNLQNLLSRVDSFDTEVPWENI
LSLGEQQRLAFARLLVTHPRFTILDEATSALDLKNEGRLYQQLQETKTTF
ISVGHRESLFDYHQWVLELVQDSSWQLMRVEDYRNQKQGITKPIVNTQVT
IDISSEDESPNEPAINTDERLSHKEMNSLTYYSVSTIRSKASKGDTITTR
DGITYRYDKDPQVLKWVRV
>Ava_4105 ABC transporter-like
MSQSSIISVQHLNHYFGKGSLRKQVLFDISLSINPGEIVILTGPSGSGKT
TLLSLMAGLRSVQEGSVKVFGKEVYRAGNKKLLQLRRQIGYVFQKHNLVP
FLTASQNVQMTMELARNMSRKEMCCRAEAMLELVGLNHRIHYYPDQLSEG
QKQRVAFARALVTQPQLILADEPTASLDKNSTQIVVETLKERAKYQGCSI
LLITHDNRILDMADRIIYMEDGYLKNDVRAA
>Ava_B0031 conserved hypothetical protein
MVMTVGDSRVGKSTVIKLLLEMYQIQGKRLKVYDHDNRDRFLAYKDLVCI
EKIDFFNTRTDRIFNDLIVDSLDIILVDMPGQYLDKICQYIIQSELLGAL
AEYGWSLTFVQPISHRTDCIDYLSQIVQTATNNANYVVVKNYHFAPEFRE
YEQTMAKNLLMIGGTEIELTALHRNHYQAMEKAGIPYSQVCQDISMILFL
RSYIYQWIKKFHDSVMDNDLAVKYLGLD
>Ava_2860 ABC transporter-like
MTTMIWMESITKTYQLGEVRVPILKGIQLGIEEGEYVSIMGASGSGKSTL
MNIMGCLDRPSAGHYIFEGRNLTTYNDDELAYIRNQRIGFVFQQFNLLSR
ATALENVMLPMVYANLPKRKRRERALEALKKVGLGERILNRPSQLSGGQQ
QRVAIARALVNRPALVLADEPTGALDTETSYEVMSLLTELNQQGITIVIV
THEPDIAAQTKRVIRVQDGLIVSA
>Ava_1097 ABC transporter, transmembrane region
MNPSSSLRVQGGLQKDPSDQLSPTPEVAILNLLRLVAGDTSLVSELSQNW
VVREFQLGDELANYVVDAATTDSSNVIYLVCQGRVRLLGFNQTLGREVST
QLVSAEQTFGADHFFCQQTLPYRAIAASDGFVLSTTIAELKPWLQAIPQL
KNYLQRLTSERQTLIFFKIYTKLHSLKSKKLQELLPYLIAKHIPNGTTLS
EATPPEKGRFWLGSGQVQSISIASFLPVVGDSWGYPESTLPDGTAQTDLL
VYQLSVENWDLARAIAPDYFTESYQPIEPPVEVVNVIPTDSKPQIALPKL
QNLRSPTAPATSDIEDIDFPQGVKQHKSRSSYSYPFIQQQSSSDCGAACL
AMISQYWGKRLSLYSLRNLAQVDRTGASLEGLTVAAQTLGYDVLAVRGSL
QKLEWHYNPWVAHWQGNHYVVVWQIKGDRILISDPAVGRKWLSRPQFETS
WTGYALLLDPTERFQALKSEKFSLGRYGQTLWNYRTVLRQIILASLLVQV
FGLATPLFTQVILDQVMPIKNLPNLHIFAFSFLCLGIWRTVLTTQHQHLL
DYFANRIDLNLIGNFINYTLQLPLQFFASRQVDDIISRVQENRKIQLFIS
RRAIAAAVDMLMVVTYLGLMTYYSWQLTLLVLSWIIPVVILTVVASPYLK
QASREISQESARQHSSMVEMMTGVATVKTATAERPLQKYWEERFLKMLKA
RLRGQKLAHRLQVTRTLINHVGSTLVLWFGATLVMGGKMSLGQFVAFNML
TGNVTHPVLSLVGLWDEFQEILISVERLNDVYAAVPEASSQTTLLVMPPI
RGEVRFENVSFRYNSFQERNALQNISFGVKPQQTIGIIGQSGSGKSTLAN
LLAGLYRPDTGRILIDGHDMAGVSPQSWRTQVGLVAQDSFLFSGTILENI
TLHDQELSLIQAIAAAKLSGAHDFIQALPLGYDTPVGERGFMLSGGQRQK
IAIARALVRNPKILILDEATSGLDAESERRFQQNLTQISQERTTFIVSHR
LSTVRYADHIFVIDQGMVIEHGTHQELMAIAGLYHHLAQLQL
>Ava_2398 ABC transporter, transmembrane region
MKYAHVQQHSQEDCGAACLASIAKHYGRTFTLNRIREAVGTGQFGTTLLG
LKRGAETLGFNARSVKTSPELLNQINEARLPAIIHWKGNHWVVFYGKKGK
KCVISDPAVGIRYLSEKDLVEGWTDWLMLLVEPNPELFWKLEDDKVSGFW
RFFKRVWHFRSLIAQVIPLNLLLGILSLASPFLLQILTDDILIRGDTRLL
TTMAIGVFVMNLISGSLAWVQSNLIAHFAQRLQLGLVLEFCRQILQLPLS
YYEARRSGEIISRLRDINQINQLVAQVVISLPSRFFIAVISFCIMVFYSW
KLTVVAMIVSVFMTISTIVFLPTLQQKTRELLIKDAEAQGVLVETFKGAL
TVKTTTASPHFLDELQSRFGHLANVTLRTIQIGIINGTFSGLVSGIGSIA
LLWVGGNLVINPAENLSIGKLLAFNSMNGNFLGLIGTVIGFVDEFTTAKT
AVQRLTEIIDTTPENEGDGKKPFTTISGDADIICTNVNFHYTGRVDLLED
FTLTIPGGKVTAIIGKSGCGKSTVAKLITSLYTLQSGNIRIGLYNLQDIA
LDCLRQQVVLVPQDAHFWSRSIIENFRLGAPFVTFEQIVRACQVTGADEF
ISRFPDKYQTILGEFGANISGGQRQRLAMARAIVTEPPILILDESTGGLD
PVSEAQVLDELLHHRQGQTTILISHRPKVINRADWIVLLDQGRLKLQGSI
EDLRTKAGEHLDFLIP
>Ava_1433 Cyclic nucleotide-binding domain (cNMP-BD) protein
MNQVIKIKELNHYYQEGRRKKQILFGINLEIQSQEVVILTGASGSGKTTL
LSLMGCLRSVQEGSLKLFAHELKGANEFERTQIRRRIGYVFQHFNLLDFM
TVRQNVILSLELQDNFTPQDAISKSTEILKLVGMEKHINAYPRDLSGGQK
QRVAIARALVHRPQLIFADEPTSSLDGQTGKEVVELMTGLAREQGSAVVI
VTHDNRIFGVTNRILRMEDGKLDLDYQGRLSVALPTLTDKQLIQLLPQLK
MLTFQPGEIVIHQGDLADKFYILMEGEVEVIQEDGDSEPKLLKRLGPNSY
FGEIGLLHETTRTATVRAASDTPIKVIVFEQSDFEKMVNSSEMTYAVLNY
QAMKAGRTQIQTPNSASIQLRQKELKILEEYCREASRTEIDVLNELINEL
SQQTRHSK
>Ava_1941 ABC transporter, transmembrane region
MQAIGRVLESLRNYRLISLGALLSLLLLTVANAVTPQLFRWGIDQGIVKK
DLQIVLYSAAWMVVAAIARGVFNFGQSYLAEAASQGVAYELRNKIFSKIQ
NLSFSYHDQSQTSQLLTRVTSDIEQIRTFIGTSLIQVISGIVTLASAAVI
LLVMNWQLALITLTVVPMSGWLMARFITQNDRLFRQVQEQLSDLNAVLQE
NLIGIRVVKAFVRESAERSRYTGLNDALVTANMKTISAIRNTFPFIFLLS
NLVTLAVFGYGGAQVIGNTFSIGELVAFNAYLVLILQPILLIGFAAPAIA
QAAASAQRVYEVVDAAVEIRDRADAIPFEICGGRITFENVSFRYPGAATE
ALKDVSFETKPNELIAILGMTGSGKSTVMNLIPRFYDVTKGAIRIDGRDV
RDFTLNSLRKHIGIVFQETTLFSGTIRENIAYAKPKASLEQVIEVAKTAQ
IHDFIISLPDGYETIVGERGVGLSGGQKQRIAIARTLLTDYSILILDDST
SAVDAKTASEIQAELDSMMRQKACVTFVVAQRISTVKNADRIFLIDKGRL
VAQGTHEELMQTSPLYGAILESQVKKRQETEKVGNGGLTTNN
>Ava_1156 Type I site-specific deoxyribonuclease HsdR
MPKPGEQKTVQSRIITYAQEIGWTFVSREEAETRRGFNNHSGNIQEKAQQ
ASLFFDDTLYQKVRQFNPKYTEAQGVLIALLSNLPADIYGNRDFLTYLRN
QGKYFYAPENRELDLKLINYDDTTENSYEVTEEYYIHNGKYGTREDVVFL
INGIPILVIECKNATKDEAIALGVDQIRRYHTETPELFVPQMIFTATEAI
GFSYGVTWNIVRRNIFNWKAEQIGQLEAKIKSFCQPNYILQFLQNYILFA
EKEETLQKFILRQHQTTAVEKVIERCHDPEHSKGLVWHTQGSGKTFTMIK
TAEMLFKAPQSDKPTILLMIDRNELEDQMLRNLINLGLNNVQHADRITTL
NQLLKDDYRGIIVTMIHKFRDMPANINLRKNIYILIDEAHRTTGGDLGTF
LMAGLPNATFIGFTGTPVDKTSYGKGTFKTFGTDDKKGYLHKYSIAESIE
DGTTLPLYYNIAPSKIIVPKELMEKEFLNLAETEGISDIAELNKILDRAV
NLKNFLKGNQRVDQVAKYVAKHYTQNVEPLGYKAFLVAVDRPACAKYKQA
LDKYLPPEYSAVVYTGNNNDTQELKTYHLDDKTEKQIRKNFAKFGEYPKI
LIVTEKLLTGFDAPLLYAMYLDKPMRDHTLLQAIARVNRPYESEAQEMVK
PHGFVLDFVGIFNKLEKALAFDSDEINAIIKDLKLLKTLFKNKMEQQAST
YLSLIQNNFNDKDVDDIIEHFREQERRKAFSKAYKELEMLYEVISPDAFL
RPYMDDYATLSSIYEVIRKAYSKRVYVDKALQRKTDELVQKHIGTTAIAT
VTDFVEINAQTLEVIKDKQGGETTKVINLIKSIEKTAEENPDDPFLIAMA
ERAKIVQEKFENRQSDTQEALDTLVKEIGENEQRKKEQAKRGFDSLTFFV
FQTLQDAGIDNPEAVSNQIKQAFIEYPNWRISEAELRELRKEVTFAIFAE
IDELDQVTAVVDKLFMLLSQAYSS
>Ava_1408 Penicillin-binding protein, transpeptidase
MVVSESSDKLRDFSRRQPANRRQRSRKVQKVESKKVKVPNQQRAGAGAAV
ITRSNNNAVPPPVAVGGRRPKQGLVMPSVVKPIPTAKGPIPPFNPNNVKV
RTVRVQKQPMSQIGRRVSRKTRLKPMARAILYAIRLLIVGVGIGAIVGTV
LSVLDPATRMAPVSTPSNTSNTGQNQSKPTPTAGLYLTQEITPLKNVVQQ
LATANPNLSPGVFLVDLDTGGYVDINAANALPAASTIKIPILVAFFQDVD
AGKIRLDEVLTMQQEMVAGGSGNFQYKPAGTQYPALEVATKMITVSDNTA
TNMLIARLGGIEALNERFRSWGLTTTVIRNILPDLPGTNTTSPKELGNIM
TMVSQGNLVSMRSRDQILDIMRQTERDNLLPSGLGAGARVYHKTGDIGTM
LADAGLIDTPTGKRYIVAVMVQRPNNDPRAEKLISSISRAAYQQFSQSEP
TPSNTTSNLPTTAYPSPIMASPATNTPINPSIAPPISNSYPAPVMNPQYY
PPTR
>Ava_3842 conserved hypothetical protein
MHVSEAEWTDIEKKIARTAFDQAYKREIEALLKQVQKEASTLVELDGLWQ
LHDFLSARRHEIEGKYDYQYSALLFVFAGLVKDGWLHVNELEGLSKDKLS
KVSALARM
>Ava_4290 Peptidase U61, LD-carboxypeptidase A
MKSTILPEPLKPGDLLQVIAPSGALREFAALKQSVEIWRSRGYRIEISSD
IDHHWGYLANKDEVRRHQLASAWQDPDCRGILCARGGFGSTRILEDWHWQ
INSDPKWLIGFSDITALLWSLYNAGISGVHGPVLTTLADEPDWSTERLFN
LVEGRTIAPLKGRGWGGGVATGILLPGNLTVATHLLSTPIQPNFDGVILA
LEDVTEAPYRIDRMLTQWRLSGVLAKVKGIALGSFTRCEAAPNIPSFNTE
EVLRDRLADLGIPIVSDLPFGHGEQNASLPVGVPVTLDANHGVLDIVTF
>Ava_1118 ABC transporter, transmembrane region
MPKSPHKLFKANSFWKENHLILREIKHFRKIAILAVIFSFLAASFEGVSI
GFLLSFLQKLTTPNEPIQTGISWIDMILAANAWPIPPIYRISLLILLSTW
MRATFNYFGGVYTESAQLNLADRLHKQIFEQLQALRLSYFAQTRSGELIN
TITTEIERIKQGFSGLAFVLTRIMTVCVYFVVMFSISWQLSIISVLIFLL
LAVGLSTLNKRVRETSFGISHANAQFTATAVEFINGIRTIQAFGTQEFER
QRFYKASTNQLNAAIKVVLAWTLVKPIAEGIATTVLISLIVISFTTFTLP
VASLLTFFFVLVRVIPNIQDINGTVAFLSTLQGSSENIKNILQTNNKPYL
KDGKLHFQGLKRSIDLVSVDFGYTADNLVLNNITLTIERGKTTALVGASG
AGKTTLADLIPRFYDPTEGQILVDGLDVQYFEINSLRRKMAVVSQDTFIF
NTSIRDNIAYGTSGASEAEIREAARLANALQFIEEMPEGFDTKLGDRGVR
LSGGQRQRIAIARALLRDPEILILDEATSALDSVSERLIQESIEKLSVGR
TVIAIAHRLSTIAKADKVVVMEQGRIVEQGNYQELLEQRGKLWKYHQMQH
ESGHSQ
>Ava_2224 ABC transporter-like
MKSKKRRNPLRQSLAVFRYSGRAIYLVWTTSHTMTIILATLTLVAGLLPA
AIAYIGKLIVDAVVLSSQANANLSQPLLYVSLEAIAVALLAGSQRGLTIC
QSLLRVLLGQRVNVLILEKALTLDLTHFENSEFYDKITNARREASIRPLS
LVNRTFGLVQNALSLVTYGILLVNFSLWAVVALILAAMPAFIAETRFAGE
AFRLFSWRAPETRQQHYLENLLAREDFVTEVKLYQLGKMLLGRYRNVFNQ
LYSEDRDLTVRRGVWGYLLSLVSTAAFYIAYAWIVIEAVLGKISLGDMTM
YLTVFRQGQSTFANALTSIGGMYEDNLYLSNLYDFLEEKVTQPGGNVTQG
INPEDGIRFQNVSFTYPGSSQPALNNISLHLKPGEKLAIVGENGSGKTTL
IKLLTRLYTPDSGRILLDGVDLQKWDINTLHRRIGVIFQNFVRYQFTVGE
NIGVGDVENLDDNRRWQVAAQKGMAQQFIETLPQSFQTQLGRWFKGGQEL
SGGQWQKIALARAFMRTQADILVLDEPTSAIDAQAEFEIFNHFRTVTQNQ
MVFLISHRFSTVRMADKILVIENGEVVEQGTHEELLADGGHYARLFLLQA
AGYQ
>Ava_1451 ABC-2
MMKYWRETIAVTKRILIELLRRRRSLIFWSIFPISVLTLSGFILAERAEL
PLADAFSYAAPSTLVGAALFFSCLGGTVSTVVAEREQQTLKRLFLSPLSG
LSYFLGIFLAHSCIGIGQALLIYAIAAFWGATFKGSILLGLGIIFLSIAA
YVGLGFILGTQLARRIEDVNSLVAAFGVPLLILGGAFLPTALFPKTLINI
AKYNPIYHMNEALVAVSSKGEPVDKIASHITFLLAFAIAMIIGGWLSYQR
MLIVERRL
>Ava_4383 Cyclic nucleotide-regulated ABC bacteriocin/lantibiotic exporters
MPSGFSRQYLAEQLTHILGESLSGRELEKCIQSLEIIEPPIAKQFWQAAT
ASAGIYIVLGGKVRLLDSAHNLITTLSTGASFGELTLFPDADFIPYVARA
SVNLKVGYLPQGILQELMGETSSVGDRLKKHAETWDLLVLCCQNSLLPQN
PSVEEIIKALALFERHTLDIGSLPSQIFPDTKLWILRRGELENNNGRTFQ
PGTISQYSKQIKWQVTQSAIVYILKHGNWQVAQEYWPELGTGDWGLGTGE
NGSQSPLPSIRPPVVREPEPQPQPKQRRAYFPSPRIQVGHWWGRLIKRYP
IFEQQSAADCGAACLVMISRYWGKRLSVNRLRDLTNVNRSGASLKGLTAA
AETIGFTTRPVKASFDKLAQQPLPAIAHWEGKHYIVVYEINKKQVIVGDP
AIGQRNLSIGEFKAGWTGYALLLQPTTDLKENEEANTSFWQLFELVKPHT
RVLVEVFSASVLIQVFGLITPLFTQLLLDRVIVQGSTLTLNAVGLGLVIF
GLFRVALSGLRQYLLDHTANRISISLLVGFIKHTFRLPLSFFESRYVGDI
VSRVQENQKIQRFLTGEALSIILDLLTVFIYVALMFWYSSAMALMSLAIV
PPFMLLAIIATPFLRRISREVFSATANENSYLIQSLSGIRSIRSMAIEQT
VRWHWEELLNNVIRKTFSGQIISNKLQIFSSALETLVTTILLWFGAWLVI
QNQLTIGQLVAFNMLLGNIIRPFQRLVVLWNQLQEVVISTERINDVLEAE
PEEDLQHQHRQFISNLLGHIRFENVTFRYHPESDRNILENLSFEIKPEQT
VAVVGRSGSGKTTLFKLILGLYPPTDGKVLIDAQDVTNIALRSLRSQIGV
VDQDTFLFGGTIRENISIAHPEASLEEIIAVARLAGADDFIQQMPAGYET
QIGEGGGMLSGGQRQRLAIARALLGNPRLLLLDEATSHLDAESERIIQNN
LKTILKGRTSVIIAHRLSTVRHADLILVLDRGLLVESGNHDQLIARRGHY
FYLNQQQLSNE
>Ava_1942 ABC transporter, transmembrane region
MRTPAPVIASEQQATKQLSTLRRFLQYLRPFRKEVPIALSLVLIGAVTQA
IGPFLLGWSVDNLIAKGNLPGLLLLLVLLGLNYSFGIWAIRGQIIRVGWI
MQRLLAQLRQDIFTKIQSLPLSFFDRSEAGDLMSRLLNDVNTVNQAFGQT
VAQMLGNTFSLVGIVIAMLSINLQLGLLSNLVVPLMIFTTSLFARWARTK
FRVTRQTIGELSAKLEEDIGSVREAQAFNRVHLNIAEFDVLNAANRDANV
EAVAITAAFLPSIDFLNTLATAGVLAYGGYLAVTGAATVGVVTSFLLYVQ
QFFRPIQILSQFYTQAQSAFAGLERIFLLLDEPSQLNDAPNATQMPPIQG
EVTFEDVKFGYNPEQLVLKGVNLHADAGQMVALVGATGSGKTTIINLILR
FYDVSDGAVKIDGVDVRSVTQASLRHQIGIVLQDNILFSGTVAENIAFGA
PYATQAEIEAAAQMANVHEFITSLPQGYTTKLGERGAPLSQGQRQLISIA
RAVLINPRILILDEATSSIDTRTEALVQDAIARLLQGRTSFVIAHRLSTV
TQANQVLVIQQGQIVERGTHAELVRQQGIYANLYALQLGAATAQ
>Ava_B0138 hypothetical protein
MSFYCVYCNRIRSGKKQSEEGKTKEHFVPTSIGGGRSWHIPACKNCNELL
GKTYDDELYRLSWMFEFYKNRSIKRTGRAILQNGHKIDVNFSYSEVFSSQ
NRNFQLECYDSDSGEEIPRIDIRRIEFELETKSKIINSYPSILKIALGGA
HYLNTRYKLTNKTFFSDLAFAKIREEILGKRNFNPGSNGISSPVICELLS
TQESENIITRCENEKTKLRHIISIEKEDENLVISVCLFSFFFWRVLIPMN
NNLKISKFEDELILHELTGTTRLITSSIMQHESPPTIVILINKD
>Ava_3587 DevC protein
MNRKRIPLSWLQLTREKTRLAVALAGIAFADILMFMQIGFRDALYYSNVR
LHTSLQGDIVLINKQSNAVLAMKPFSQRRLYKSLELPSVQSVHPIYLDYS
IWKNPYTGLTRSILVFGINPETNILNLAGVQENLDKLKLPDAVLFDRSSR
PEYGPIAKNFEQGQSISAEVRRRRINVVGLFTLGASFGADGNLVTSDVNF
LRLFPLRRQGLIDIGLVRLKPGVNPNTAVQELRSYLPDDINVLTKQEFID
FERNYWASSTAIGFIFTLGTIMGFIVGTVIVYQILYTEVADHLSEYATLK
AIGYTQKYLLGVILQEALLLACLGYLPGWVFAMVLYQTARQATLLPVFMS
YDRAITVLILTMIMCFVSGSIAVRKLRSADPADIF
>Ava_2544 Acriflavin resistance protein
MQQVNKSGGFSISTVSIRQHIGTLMLTLAVMVLGVFFIINLPVDLLPSIT
YPRIGVRIEAPGVSPEVAIDEVTRPLEEAFSATEGVVQIFSQTREGQVSL
DLFFQPGGNIDQALNDATAAFNRARNGLPDTIEEPRLFKIDPSQLPVYEF
ALTSPSLEGLDLRVFAEEELARELGVVPGVAGVDVSGGVQEEVRVNIDLD
RLQALGVGLNDVLDELRNRNVDISGGRILGQNSEPLTRTVGRFQSADELR
NLSFEVSSTASSNPSQQSTVNSQPSTINNRRVYLRDFAQIIDGSEQQRIY
VSLNGEPAVKVSVQKQPDANTINVVDAVKKRLEELRQSSVVPEGTVITPT
LDESRFIRNSISNVTSSGLIGTALAAIAVLLFLGSLRQTFIIVIAIPLAT
LAAIILMGLFGLSINVFSLGGLALGVGIVVDNSIVMLESIAEGVGMTPGK
DSKSRLSHKQLIAQAETSSQEVESALVASTSTNLVAVLPFLLIGGFIALL
FNELILTITFSVAASIVIAVTVVPMLASRLLGWKFSSGLSNFWPLRKFNE
RFEAATRGYGRFLAGILRWRLVTVAIAILLFGGGSLWMAPQIPQQILPRI
STGQASLFAQFPPGTPLETNSKVMSAVDEIIRQQPETEYTFTTAGGALFG
TNTNANPLRGTSTITLKPGTNVDTYVERVTQELNKLNLAGIRLRLAPGQV
RGLITNNSPVRNADVDVILQGTNADTLQQASRQVLAALEEQATQVRFRPD
ADERQPEIQILPDWERVSALGLTTRDIGDTIQTALEGSVPTQLQRGNRLV
DVRVQLNESAVQTGSQLQRLPLFVGNNRQVRLSDVAKIVEAQAPGEIQRI
NQRQVIIFAGNLTEGASLSRAIEQVNNVISNLELPEGVSVLPSAAAESNR
QLQSSLQLLGGLASFLVFVVMAVQYNSLIDPLVIMFTIPLALAGGIFGLY
ITNTAIGATVIVGAVLLVGIVVNNAIIMVELANQIRDRDKVDRRTAILQA
APQRLRPILMTTITTVLGMFPLALGIGEGSEFLQPLGVVVFSGLSLATLL
TLFIIPCFYTLLHDLLSGAWSKPVFIWWRVWRKRFTL
>Ava_0389 HNH endonuclease
MGKVLVLNASYEPLNITSWRRAVVLLIKGKAERVEHNGSFLYSDFPLPTV
IRLRHYVRVPYKEIPLTRRNILHRDGHTCQYCGYTGDELTLDHVNPRSRG
GGDSWENIVTACVRCNVKKGSRTPQEARMPLRHLPRQPYSSLYFEVSKHL
KNGLHQEWQKYVIGL
>Ava_C0122 HNH endonuclease
MSKVFVLDTEKRPLDPIHSAQARQLLRNKKAAVFRRFPFTIILKESRADA
SVSDLRIKLDPGAKITGIALVNDSTGEVVFAADLKHRGFAIRDALISRRQ
LRRTRRNRKTRYRKPRFLNRTRSEGWLAPSLMSRVHNVETWVNRLRKFAP
ITAISTELVKFDMQLMRNPEIEGKEYQQGTLAGYETREFLLEKWNRQCAY
CGIKDIPLQIEHIHSRSKGGSNSITNLTLSCEKCNVKKGTKDIKDFLKKD
PTRLQKILAQAKKPLADAAAVNATRYKLLEVLKSTDLPVECGSGGLTKFN
RTNQQLQKTHWLDAACVGQSTPILIIKGIKPLLITANGHGTRQMCRTDKF
GFPNRYVPKLKFIKGFQTGDIVKAVVTNGKKIGEYIGRVAVRSTGSFNIS
AQRGLIQGINYKFCKSIHKKDGYSYSS
>Ava_4735 Acriflavin resistance protein
MNNLFYQNVRLLILTVLAIAVWGLSSFFSLPRIEDPEITPRFAVITTVFP
GAAPERVETLITDKLEQSLFEVEEINNIESTSRLGFSSITVELNDTINDV
DPVWSRVRAKINDTIPLLPSGAATPKFEQSKPKANALIVALTWDLKSAPN
YAILSRWAQELDDQIRLIGGTEKVEQFGTPQEEIAIEVNPKQLTNLGLTI
QSLSQQILQSDAKVAAGQLRSNQSNLLLEINGELDSLDRLNRLSIQSGNS
SNVVRLGDIAQIKKGILDPPRELALVNGRRAIAISAFVESQQRLDAWAAI
ANTTLKKFQQQLPKGVGLQILFDQSHYVEQRLNEVLMNLITGAVLVVGIT
LFMMGWKSSLIVGSALPLSVFMVFGSMKLLGVPLHQISVTGLIIALGLLI
DNAIIVVDEVQIYLREGLTPKKAVATTVREIFSPLLASTFTSVLAFVPIA
TAPGGTGEFTGTIGVTVILALVSSLFLALTVIPALAGRLHYWKPTPVSGS
WWQVGFSHHHLGQFYSWSLDRTFSRPLLSIALSLILPLWGFMSLANLEQQ
FFPPTDRGQFYLNFELPIQASLQQTQSQVTQARELMLRHPEIADVQWFIG
KSAPPFYYNVIQNRENSPNYAQGLVQLQKNVKSGSLIRTLQQELDQAFPA
AQIIVRQLEQGPPFDAPIELRVYGSDLDRLRELGDQLRAELAKTPNVIHT
RANLTETLPKLALNLDEEQLRLAGLDKTAVARQLDTNLEGIVGGSIFEGT
EELPVRVRSLESERGNLGDIASSTLLSPGNSNQSGNRVVPLSAVGNVEIV
PDVVTISRRNGKRVNTVQGFIPAGMLAAQVQTDFQNRLTASNFTLPSGYS
WDFGGEEGERGDALSNLISTVGVLMIIMIASLVLTFSSFRLASIILVVAI
LSMGLGLGSLALFNYPFGFTAILGMIGLIGVAVNDSIVVLSSLNHDPKAR
QGDRYAARKVVIRSTRHVIATTLTTIIGFTPLLLDTSGFWPPLAITIVGG
LGGATLIALYFVPSVYLLLQRSLVKDSKK
>Ava_B0237 ABC transporter, transmembrane region
MIKYPVVLQHNEEDCGPACLATICKYYGRLFTINRTREAAGTGQLGTTLL
NLKQGAQVLGFNARGVKAVIDLVDKQQIPLPAIIHWKGNHWTVLYGRRGK
QYIVADPLVGVRYLTKEALLTGWTNGVMLLLEPRPDFLSQADDQDKVGGW
KRLGQRLFSYRHILAEALLLNFVVGLLALLSPFLIQILTDDVLVRGDTQL
LTGIALGVLAMSLISSALQWVQGNLVAHFAHRLELDLVLEFGRIILRLPL
SYYESRRSGEVVSRLRDIQTINQLVSQVGVTLPSQLLIAIASLALMLFYS
PKLTLASLFIALFMPLSTVVFFPSLQQKIRNVLGIAAENQGILVETFKGA
LVVKTTNAAPEFWQEFQTRYGRQANFMFRTVQIVITNNIFSGWVATSGGI
ILLWFGSTLVINREITIGQLLAFNSLNTQIIALVNTVVGFVTEFTRAQAA
TERLNEVIQSTPEFPEVNHKPFVNIPDNAEIICSYLNFHHPGRVDLLQDF
SLTLPGGKVIAIIGQSGCGKSTLTKLLAGLYTPQSGNIRIHRYNLQDLSP
DCLRQQVILVPQEAHFWSRSILDNLRLGNPQVNFEQVVTACQVAGADTFI
SKLPEKYQTILGEFGANLSGGQRQRLAIARGIVTHPPILILDESTAGLDP
KTESVILDQLLAYRQGKTTILISHRPHVIKRADWIVLLEAGQLQLQGTLS
ELLNIPGEHLDYLIS
>Ava_0600 DevC protein
MFQQLRRRTPLGWLQLSHERSRLLVALSGIAFADLLMFMQLGFQAALYDS
NTTLHRSLQADIIVIGSQTRNLQRISMFSRRRLYQAMDVPGVKSAEAMYV
SNMLWKNPQTRRDTEILVIGINPDRPAVDFPEVNQKLSEIKLPDTVIFDR
ASRGDYQETIAQLEQGQPVKTELERRTVTITGLFKLGASFSADGTLITSD
QNFLRLFPRQPASSVSVGLIQLESKANRQQVAAALKSRLSQDVKVLTHDE
FIEFENNFWRTNSPIGFIFSIGVSMGFVVGVIIVYQVLSTDVNTHLREYA
TFKAIGYRHYYLLGVIFEEAVILALLGFLPGLSVSLGLYHLTRTATNLPM
YMTVIRALQVLILTIIMCAISGAIATRKLQAADPAEMF
>Ava_4151 ABC transporter-like
MSKSLASSPNAVILETQGLTRYFGKAVAVKDLSITVQQGEVFGLLGPNGA
GKSTAMKMLTTLLPLSAGRATIAGYDVTHQAAAVRRLFGYVPQALSADGS
LTGYENLLIFAKLYDIPVKHRQRRIREVLDFMGLQAAAHRLVRNYSGGMI
RKLEIAQSIMHQPKILFLDEPTVGLDPIARTQVWQLVQQLRADYGTTIFL
TTHFLEEADSLCSRVTIMQQGQVVITGEPSDLKASLGKPNATLDDVFIHY
TGDQLTSGVNYRDTARTRRTSQRLG
>Ava_4225 Type I secretion system ATPase, HlyB
MLAAIPWNQPPLNWLTSEQRSLLEERLEIRRYRLGEKIWSSEAGGYQFFI
VAGKVRLREEGSGQSLAAIQMGDWFGDLQKLPGEYKAVAASKEVIVACWD
THLWAQISTPAMEDFWLGLAKQEHTEMENEVTSVQSPALQQPLTPPEQTP
QIPPPVTLSYPFVSSWNTGAACLTMAAQHLENAVNLEWVQRQLRGQSPKQ
VVEAGEKLGLVLRRLQMTWGELRQLTFPALLQLQAESMPDPSWVIAYGLK
GDRLIIANPLNPDNLCESLPESVVEQCWDGQLWQVELISKQEKFNLSWFT
PAVWKYRKLLAEVLLASFTLQLLGLGTPLITQVVIDKVMVQESLPTLDVM
AIALLAIAVFESILGILRLFIFTHTARRLDLSLSAQLFRHLMRLPLAYFE
SRRVGDTVARVQELEQIRQFLTGTALTVILDSIFAVVYLALMFYYNIPLT
FVALAVLPLFATLTIVATPILRNWLNETFNRSADSQSFLVETVTGIHSVK
AHAAESVARDRWEGLFARFVRTGFKASTTSNISSNIGDFLTNFSSLLILW
FGAKLVIDQKLTIGQLVAFQMLSGRVTGPLLRLVQLWQNLQQVLLSVDRI
GDILNVAPEAEMGTGLVLPPLKGQVSFEQVFFRYKTNTEPVLRGISFNVE
PGQFVGIVGRSGSGKSTLSKLLQRLYQIESGRILIDGFDIKSADLSSLRQ
QIGVVLQEDFLFNGSILENITLGNPDITAEQVVEAARLAVAHDFISQLPY
GYETNVGERGTALSGGQRQRIALARLFLCDAPILVLDEATSALDSETEQQ
VLQNLQKISANRTVFLIAHRFAPLKRADLILVLEKGVIAERGTHPELLQQ
KGLYWSLYQRQQANV
>Ava_A0017 hypothetical protein
MLSQFLPDEPNQPTEIKTSIIKIRGKTLIYGNVVYQIHNIASIGLVDLTT
TVIKPMPKLFVVLPIIGVIFLFITSYIAKLIGFLLIVIGAWLIYQHNLNK
TKTTERYGMTIYTNSGTKTILTSRSEDFLKKVILTLYTVMNSDELKAVNF
NFETLDMSVDNSIKVGKNIGSPLNTGHIGGDVVNQV
>Ava_4147 ABC transporter-like
MIKKTRLSKSFQRAANAPKLPNTTFRFICYFVNQFRWWYVAMVIAEVIHA
TCGIMLPYAIGEIIRSVTRSPGDSKSIFDAVSQPLMLFSALSVGEVVFGR
TAGLLQTILHPIHRQHIVRSLYAYLQHHSHRYLSSSFAGSLAHRIGETSL
GVTQTMQMLITEFMSVIIVYIVSTILLYRAYPPLAAFVGTWAVLFISISF
WLATRCRIYSRKAAAARSETTGIIVDAVTNLSSSRLFARLGFERSYLNEQ
LRRELKQVRKSNWYSERIRWFQFISSAILKIGTLYYSLSLWSRGQIATAD
FVVATSLSLLIISEARNLSKRFLEFFEHIGNIANGVYTIVQPHELVDRDQ
AIAHSITQGKIEFRQVNFSYTDGKKVFENLSITIQPSQRVGLVGFSGSGK
STFVNLILRLFDPQSGQILIDGVDIRDMTQDALHSQISLIPQDPSLFHRT
LMENIRYGRLDATDEEVSEAARQAHAHDFIVPMQEGYDSLVGERGVKLSG
GQRQRIAIARVILKNAPILILDEATSSLDSITEKAIQDTLDLAMNEKTVI
VVAHRLSTIAHLDRILVFDQGRIVEDGTHTKLLARRGAYYKLWKMQAGGF
LPIEAEQGEDKKLIKQLDSNQASTSDLNVTKNR
>Ava_0325 ABC transporter, transmembrane region
MLTRRILLKFAKPYPGLILLTIILGFSGALFNGISTALIVPVILRIVGQP
VDLKGAPGLLKAIMTPFDNVPENYRIAAMAGAIILTIALKNLATYTSTLS
SSSLTRRLTADMREAGIDLLLNIDIDYYAKTKVGDLINRLGGEIGRAASY
VGNIIKLVILSITISVFICLLLSISWQLTIMAAILLSLVTLVNQFAISRS
RKFGKILSEMSKAYSIAVLETLNGIRLVKTTANERKEFNRIKRLIREREL
ADFKAQMNSNAITPLSEFLGVTSLLIIVLLSKTFFADQISTLSAVLLTYL
LILLRLLPLVSQLNSLRSSFASMNASVDSVNDLLRLDDKPFLTNGKIAYN
GLQTGINFKSVSFTYPGHDKQVLKDVTLKLPRGTTLALVGGSGAGKSTLA
DLLPRFYDPTGGCITLDDVDLREFDINSIRKCMGVVSQDTFLFNNSVRNN
IAYGKQEATEEEVVAAAKRANAYEFISKLPQQFDTMIGDRGVMLSGGQRQ
RLAIARALLQNPDILILDEATSALDTVSERLVQGALEELSRDRTTLVIAH
RLSTVRKADQIAVLEQGKVVEVGTHEELLQKGGYYSRLYGMQFSNNSETT
NRTNQSLLRISHEIRTRLHSMIGVLRLLLDDVTDNNQEHQELIEDSYKSA
FKIINTLDIFEDTLQQQVYYLSTSLSEDNQNNNTLLEHLKNINEFRIQFN
NILVSLRSLTDSTGELEQSEYLLLKESLNVSMNLLDCLENVETGIF
>Ava_3499 Restriction modification system DNA specificity domain
MNCIELSLADTCEFINGGAWSDKEYVEAGIPVVKVTNMVDGTIETNNLSY
LPLSSSDKYKKHLLFVNDLVVTTVGSHPTQPGSVVGRTSVVPQHFDGAFL
NQNAVCIRVKCKNLISPKFLIYISKTILFKHHIESRARGSANQVRMALGE
LKKFTFKFPPLPVQKKIAAILSAYDDLIENNNRRIAILEKMAEEIYREWF
VRLRFPGHEQVKFNKGIPESWERKRFDEFCLLQRGYDLPDTQVIPGQYPV
IASTSIKTYHNQFKVNPPVITTGRSGSLGIILFINSQAWPLNTTLFVKNF
YGNSPYLIYYTLKFLKLENFNSGAGVPTLNRNHLGGLYMSVPPKSLQNNF
NDKIAILFKQKELLSKSKNALIEIRDRLLTRLISGKLSVEDLDIQFPPSM
TEELK
>Ava_1452 ABC transporter-like
MLNIHNLNKSYGDRQVLQNLTLNITNSEIYGLLGANGSGKTTTINIICNL
LKADSGEIKLNNQLISESTKKLIGIAPQENLLYKTLTCEENLQFFGEIYG
LSRKNIQKQTKDILDAINLSDRAKSPVETLSGGMQRRLNIAVALVHQPKL
VILDEPTTGLDIEARYEIWELIRRLKTQGITVLLTTHLLDEAERLCEKIG
ILKNGQILVEGSLAELRNLIPAQEVLLLKTTQEKEAIARAQTYGFTHRYY
DQELAFWLPESLELKEIISRFEGINIEAISRQPVKLEHIYLEVTQQI
>Ava_3638 ABC transporter-like
MLQEFLPGTTNSQSFDLEPVISVSNLNHYFGSGSLQKQVLFDINLTINAG
EIVIMTGPSGSGKTTLLTLMGGLRSAQEGSLKILGQEICGASKNQLTKLR
RQIGYIFQAHNLMTFLTAKENVRMSLELHDEFFHEDINAKAIAMLETVGL
GERVNYYAENLSGGQKQRVAIARALVSHPKIVLADEPTAALDKKSGRDVV
ELMQKLAKEQGCTILLVTHDNRILDIADRIIYMEDGQLKSDDMDIAAKMH
>Ava_1432 Protein of unknown function DUF214
MIQRYFLELQKIPIAWLQLSYQRNQTIAGIIGILCITFLLFIQIGLRNAF
LEGSLQLPLNFNADIVLISSLSSTALQPVTFSSRPLYEALALKQVNSVAP
VYITSTQWYDRNNSLYRIRVNVLGIPLNISTLNLPGVKENLQKLKKQKFA
LFDHNARNEFYPIIAEFQAKGESAAEIQVGNTSSLRGLRVVGLFELGVNN
AYDASFIISATTFSELFGRDNSQIDIGLIKLKPEYNSDVDIEKTVDDLRN
YLPRTIKVFSKSELIKRERTFHENNSPMGFIFRFILIIAVVVSIFILYQI
LYVKVTQNLGNYATLKALGFSQKSLISVVIHEGIILVIAGYIPGIILSYL
AYSYLINVTKIFIEMNLRTALTVLLLVYMICLISSILSLIKIKDADPVDV
FK
>Ava_0687 ABC-2
MASQKSLIWGKKFKTSQLQILLADSLTIFWGDWLDLRVRVAQVAASGLIS
PLIYILAFGLGLGSSIRPGSAISGNYNNYLEFILPGMVALSSMTISFGGT
TFSICGDRLFTKTFEELLLTPIHPLALQLGKMLAGVVRGLMTSGSVILVA
LIITRNWNFLHPLFLLLLILNCAVFAGLGVIVGLSVRSLESVGLYNNFVI
IPMSFLGATFFDPSTLPTAFQVVVYLFPLTYASTGLRAAANLPLSQFPWY
SIPVLLVIAIALSLWGASKFAHQQD
>Ava_0205 conserved hypothetical protein
MKEKLLNWLNLILVADVFLVLLGFFWFAIAVMGEAIGVNLGLDLWHKLWQ
PVFNPAIGILMGGAILSGLISWVSRKFFKKPTTDY
>Ava_1955 ABC transporter, transmembrane region
MGETPYVPVADSPVPSHQNPVPQFMTKSRRITKLAAYLRPHWREAALGIL
ALLSVNGLGVYIPWLIRACVDLLSTNFSWNQILRYVVVIILLSSAMLLIR
MASRIWLFGVGRQVEFDLKQRIFEHLLKLEPAYFATNTIGDLISRATSDV
DNVRRLLGFAVLSLANTLFAYVLTLPVMLRISVDLTLAALAIYPLMFVLV
NLFSNRLRQEQAKVQEQLSDISELIQEDISGIALIKIYAQEENERRAFAQ
QNQKLLSANLELAKSRNILFPLIGGLASLSSLVVIWLGTSRIAEGTLAVG
DFLALLIYIERLVFPTALLGFTISAYQRGEVSVDRLEAILSVEAKIQDAD
AAIHLELAEVKGELTAKNLSYAYPGVENPALDKVSFTIAPGETVAIVGAI
GSGKSTLANALPRLLEVAPGQLFLDGQDITQIALADLRSAIAYVPQDSFL
FSTTIKNNIRYSDPVSPPENVEYVAKLAQIHPEIINFPQQYETIVGERGI
TLSGGQRQRTALARAMLVNAPVLILDDALSSVDNQTATQILNNLSSGTER
KTVVFITHQLSAAAAADRIFVMDKGQIVQVGNHLELLQQAGLYRKLWSQH
QVAELLS
>Ava_2586 DevC protein
MNFKIPLAWLQLVQQKIRFLIAVAGIAFIVLLMFVQLGFQDALYSSATAV
HQNLRGDLFLVSSQYKSLTASQSFSRTRLYQALGFDGVESVSPMYLQFAK
LKNPETGEKYSIYVIGFDPGQPVMNIPEVEENLDKLKIPDVMLFDRDSRP
EFGPIAANFNKGDTEQTIEIFPFDAPIGYKVRVGGLFSLGPSFGVDGNLI
VSDSTFLRINPNTRPAEKIDIGAITLKAGADQERIVANLEANLPNDVRVF
TRKGFIDFEKQYWSVRTPIGFILNIMLTMASVVGVVIVYQILYSNIATQF
IAYATLKAIGYPNIYLLNVVFQQALILALLAYIPGFLFAVGLYDFAMTAT
KLPIVMTANNALIVFVSVVLMCITSGALAINKLRSADPADIF
>Ava_B0238 Lanthionine synthetase C-like
MKKFNYEDATWYRAVSLTERIAAMSLTAPLNADLGQRRFQRWRMQSPFMN
EALFVQRLAIDGLKVDDFCYLLGQTAPQIPQAWLGKLTAVFSNPEDEEII
EIQGLPDPHLGLLNAIAPCIRQGMMQLRVGVDNLQNIPIDISNIDSIFLQ
GLPEQLLFMLHPTLVLELNVARLQGLLTGDTAEERFSSFVQRLQTGEARL
MLWQEYPVLARLIIEEIQRWVTTSLEFLQRLGDDWEEICHHFQPNNPGKL
IKIQRGAGDSHHGGRSVFILEFESGWQLVYKPRSLAVDEHFQELLLWLNQ
QGTHPPFKTLKILNRGDYGWMEFVKAQKCTSLEEIQRFYQRQGGYLALLY
VLSATDFHFENLIAVGEHPILIDLESLFHPRSHEATTTAAATLDREMIAD
SVLRVGLLPQLVWGNTQAAGIDLSGLGGAAGQVTPERVPQLEKIGTDTMR
IVRRQVVLAGSQNRPTLNEKEVNVQAYTPAITQGFTDVYRTLLQHRQELL
KILERFVADEVRVVLRPSRSYALLLRESYHPDVLRDALERDRLFDKLWVD
VQNRPLLTQVIRAEHQALWQGDIPLFTTHPHSCDLWSRDTNLHLPNFFTQ
SGMELVHHRIQQLSERDLQRQQWFIQSALATLGINTNTDQHQVKHSASIS
NSQIPTPHSPLTAACIIADRLELLAHKNGELINWMGVTVTNNHQWTLAPL
GTDFYEGVPGIAFFLAYLGEITQNYHYTRLAKAAIKTLQQQLIRDTDTIK
FIGAFSGWGGIIYTYTHLGTLWQNPDLIADALTLVKKLPGLIVQDEQLDM
IAGVAGCIASLLSLYQVFPNDLILDVALECGEHLLNQAQIMDDGIGWISP
SGGKQPLTGFAHGAAGFASVLLELAQITGKQEFQTAAIKAINYERRHFSP
EAGNWLDLRTPAQNQFMTAWCHGAPGIGLGRWRALKYLDDPEIHKEIAIA
IHTTINQGFGDNQCLCHGDLGNLDLLLLASKIQPELTSHTSPITNQILNQ
IHQHNFYCGVPLAIETPGLMTGLAGIGYGCLRLDHPEKIPSILLLEPPHT
NSKFKIQN
>Ava_2962 conserved hypothetical protein
MMQNFMYKLSEWNPQLLREIKGRWQLRNILLAVAVSLLSQFILFIYCQTQ
LPAQYINSYSSYEITHKYCTGVTNDFNSPSCLLDEYDRVIINWQLWSQDV
FTLLSFTAILTLLVGGAYLLISDLATEERRATLNFIRLSPQSPESILYGK
MLGVPILLYFGLSLAIPFHLSLGINAQIPLIQILCFYGVLIVSSIFYYSG
ALLFGLVGTWLGGFQAWLGSGLILGFLLLAKAALRDSRTGNYPFTIFHLF
SPNYFLNDYSGEFEFAGIHWFALPLGSSLPIMVCFNILVYLIGTYFFWQS
LNRCYRDKNATMLSKKQSYLLTSCFVILTLGFANWQSQFLDKSYSYLGLK
ENLATLMFLDLGLFLYLIAALTPNRQTLQDWSRYRHMYMYQKLGKSKLIS
DLIWGEKSPGILAIAINAIIAISCLIFFTLVVPGSTSDKLIVLLSVVFAG
SLAIIYAALAQLLLLMKNEQRLFWANGMVGTVIILPPIVLAMLFSNPGNQ
PFLWLLSVAAPIIILYPSTGYIPTMTAFLALLGHGGILGLLMFQITRQLK
KSGESATKALLAGN
>Ava_4572 ABC transporter, transmembrane region
MGYVLATLTLINFAGKLANPFGQGNVAAIAQLAAILGLVFLVRGFFQSVQ
DIYMSKAALRVAFYLRKQVYGHLQKLDLSYFETAKAGDLSYRLTEDIDRI
GEVVNKLFHDFIPCVLQLLAIPIYMIYLNWQLTLATVIVAPFMGILIGWF
GERLRKYSLRSQNRVSDLSAILTEVFSGIRLIRAFAAENYEVTRFSRESE
RSFQAKYSAERLKAVQIPIVGFLEALSALSLLLVGAWQIQQNNLTVGEFF
SYLAAAGLLIDPIGHVTNNYNEFKQGEASVDRIFELIAIQPTVLEKPNAV
TLPPVKGKVEYSGVTFAYKPGEPVLKDINLLAMPGEAIALVGASGAGKTT
FVNLLPRFYDPSTGQILVDGVDIRDVRLQSLRRQIGIVPQETIMFSGTVA
QNIAFGQDVFDLEAVAAAAKIANAHQFISQLPESYNTWVGERGVNLSGGQ
RQRIAIARAVLLNPQILILDEATSALDSESEALVQEALERLMQNRTVFII
AHRLSTVRRCDRILVLERGQIVESGTHEELLALENRYARFYTQQFS
>Ava_1129 ABC transporter, transmembrane region
MVSTKSTVVTLFNPWQYVKKILLSRRLRVKTPTLLQMEAVECGAAALGII
LGYYGRIVPLPQLRRDCGVSRDGSKASNMVKAARTYGLEAKGFKKELKQV
QKLYPPYIVFWNFNHFVVVEGFDKHQVYLNDPATGPRHVSLQEFDEGYTG
IVLVMEPGAEFQKGGRKPSMIASLWSRLQGAESALVYCIVAGFFLTIIGL
VIPVFSQIFVDDILVQGRQLWLRPLLVAMAIAAILQGSLTLLRLHYLRRL
KIRLAVGMSSRFLWHILRLPVSFYAQRFAGEISNRTNLNDQVADVLAGQL
ATTIIDTLMVLFYALVMVQYDWVLTLLVVSFAAINVLTLRWISRQRVDAN
QRLIQEYGKAAGVSIAALQSIETLKASGLESDFFSRWSGYYTKALNSQQE
LGITNQTFSVLPTVLSALSAMLLLVVGGFRVMDGHLSIGMLIAFQGLMSG
FQQPVNNLVNFGTTLQELEGNLIRLDDVLDNPVGEEGIGVQGCVGGEISS
PLIYALPKLQGYVELKNISFGYSRLEAPLIENFNLSIKPGQRVALVGGSG
SGKSTIAKLVSGLYQPWTGEICFDSQPREEISSQLLTNSVAMVEQEILLF
GGTVRDNLTLWDTTVPDKNLMRACQDAAIADVIFSMSGGYDAELIEGAAN
LSGGQRQRLEIARALVNNPSILVMDEATSALDAETEKIIDQNLRRRGCTC
IIVAHRLSTIRDCDQIIVLERGKVVQQGTHQELWQVEGAYSRLIRTEG
>Ava_4104 DevC protein
MAAITPVAWLQLIHRKPRLLVTITGVTFAVMLMFIQLGFRDGLFEDAVVF
HKQIQADLVLLHRDTERFFDMKVFPRRYLYNISAVDGIESVNPFYFSVTN
FKNPETFVSRPIAIAGFTPDQPVFNLPEVNQQAEVIKAANTILFDRLSRP
EFGSIVENLEKHGEVTTDVSNRQIKVRGLFSLGGGVMTADGVIITSDLTF
SEILNHPLEKVQMGVIKVKPGVDPQSIIKKVSQDLPQELKIMTLADYIQL
EKDILAQSTPIGFIFNMGTVIGCVFGGIIVYQILYTQISDSIFIYATFKA
IGYANSYLVKVVLQQAFLMSLIGYIPGFAICMYLYSFVQEATRLPMIMTI
TRGVMVMLLTIIMCSIAGMLAMNKLRSADPAELFG
>Ava_0418 ABC transporter-like
MAAAVLLENVYKFYNNTPVVNDLSFNIEAGEIFALLGPNGAGKSTTIRML
TTLTKPSQGKMEVAGYDVVRQPLLAKQSIGVVLQQTSVDGDLSVWENMEL
HGRLHHIPNPQRQRLINQWLDYVELADRRESLVKTLSGGMKRRLQIARAL
LHQPQILFLDEPTVGLDPQTRRRLWEIIRDLNKQGMTMLLTTHYMDEVEF
LCDAFGSTKPGRIGIMDGGKLISLGTLKQLRSAHGEGLIMKQLSVTTTSN
DSSRGWEYLFFPSLEEANIYLNQQPDKTGMMVRPSNLEDIFVELTGRQLN
>Ava_0191 ABC transporter-like
MAPAVLIQNLQKRYGTVEAVKDVSFQVEPGEIFGLLGPNGAGKTTTLRAL
CTLTTPDAGKIEVSGISVLDNPRVARQRLGYVAQEVALDKVLTGKELLQL
QAALYHLPNAVAKQRIETVLDLLGLQEYANKKTGTYSGGLRKRLDLAAGL
LHSPDVLVLDEPTVGLDIESRFVVWEFLRKLRASGTTVVITSHYLEEIDA
LADRVAIIDRGVVIAVGTPSELKDRVGGDRITLRIREFSPTPEAEQAKSL
LQELPFVKEVIINNAQGNSLNLVVTPQNDALITIQQALKNASLPIFGIAQ
SRPSLDDVYLAATGRTLLDAELAAVANRDPKAEKKQNMR
>Ava_0227 HNH endonuclease
MASRKISDAIQQQIRQRASELCEYCHASEKWQYVLFTVDHIIPLSQNGED
TIENLALACFHCNRRKSAKTTALDPESGLEVPLFNPRQSLWSEHFIWSAD
KLKINGLTPTGKATIAALNLNRERIVNIRAADKVVNRHPPPEDPIEEIS
>Ava_3271 Putative RNA methylase
MSISTTIKTIQDIMRKDAGVDGDAQRINQLVWMIFLKVFDAREEEYELLE
DNYKSPIPEGLRWRNWAADSEGITGDGLLDFVDNALFQTLKELRTTATDA
RGQMIGKVFEDAYNYMKNGTLIRQVINKLNEVDFNKKDQKKQFSEIYEKI
LKDLQSAGNAGEYYTPRAVTKFIVDRIKPQLGEIVFDPACGTGGFLTAAI
DYIRQHFQSADVPEILQRTIRGTEKKPLPFNLCVTNLILHGIDVPSAEHD
NTLARPLRDYSPHERVDVIITNPPFGGMEEDGIEDNFPATFRTRETADLF
LVLIAHLLKEGGRGAIVLPDGTLFGEGVKTRIKEKLLQDCNLHTIVRLPN
GVFNPYTGIKTNLLFFTKGEPTETIWYYEHPYPAGYKSYSKTKPICFEEF
APEQEWWDNREENEFAWQVSIADLKANNYNLDIKNPHKVDVEHADLDEML
AAHQKLMAELGEVRSKLKFELMEALEGNN
>Ava_3267 Restriction modification system DNA specificity domain
MKIDTFFQNFELLTDTPNAIAKLREIILQLAVMGQLVPQNPNDEPAYVLL
EKIKEEKEYLLQNEKNKKNEFIEIKFDFNNKCLPGWVDTKLGYLIELVSG
QHLGQEEQNDQGEGLPYLTGPADFGEFNPVATRWTNTVKALAKKNDILIT
VKGAGVGKANILSMEKAAIGRQLMAIRPILLEYEFIYLLIISSYEKFQAL
SIGSTVPGMGRKDILDFSLGLPPLAEQKRIVEKCDRLLSTCDEIEKRQQQ
KQESVVRMNESAIAQLLSSQNPEEFRQHWQRICNNFDLLYSIPETIPKLR
QAILQLAVQGKLTRQDPNNEPASVLFEKIKFERKRLLGETNFREPKELKP
IRDNEILFELPKEWVWTRIGEIFLISSGTTPNRTNHKYFEDGTEYWVKTT
DLNNETVLNCEEKITKQAVLDCNLKYYPVGTVCVALYGGAGTIGKSGLLG
IETTINQSVCGIYPNKYVNAKYLHLYIKLIRPLWMNFAASLRKAPNINAG
VVNNMVFPLAPLAEQKRIVEKCDRLMSLCDTLEAKLKQGRDSSEKLMEVA
AKQVLTA
>Ava_0599 ABC transporter-like
MLKVISVRNLDHYFGNGSLRKQVLFNINLEISAGEIVILTGPSGSGKTTL
LNLVGGLRSPLVERSSSPLVERTSSQSASLRVLGQELYGASAERLVQARR
RNGYIFQGHNLHGSLTALQNVKMGLELHQYIELAELETRAIQILEQVGLG
NHLHYYPDQLSGGQKQRVAIARALVSHPQLVLADEPTASLDSQSGRDVVN
LMQKLAHVKGSTILMVTHDHRILNIADRIVQMEDGRLMSPTPAVIS
>Ava_3588 ABC transporter-like
MRQEAVIAIKSLNHYYGKGALKRQILFDINLEIYPGEIVIMTGPSGSGKT
TLLSLIGGLRSVQEGNLQFLGVELSGASQNKLVQIRRSIGYIFQAHNLLG
FLTARQNVQMAVELNEHISQEEAIAKAEAMLKAVGLENRVDYYPDNLSGG
QKQRVAIARALVNNPPLVLADEPTAALDKQSGRDVVEIMQRLAKDQGTSI
LLVTHDNRILDIADRIVEMEDGILARDSQTAIVSYDSGAWSETP
>Ava_3259 HNH endonuclease
MSVELYKQVKQKRQHPNLPVYQWKRQPLEQWKITRHSIYSRDEGLCQSPD
NRPPKVNGLCQRTVSLKTAHIDHIRPLSSGGSNHASNLRTLCPVCHALRL
DRKHDGMRNKLVKKGLIPVNWKQFVWDG
>Ava_3498 N-6 DNA methylase
MTPEELKQLEANLWQSADTLRANSDLKSSEYSTPVMGLIFLKFADNKYRQ
YAAEIQQEYEALKGTRREKAIAEIAIEKCGFYLPDHARYNYLLNLPEEED
IAKAIKAAMVSIESYKPELKDTLPQDEYFRLTRTDKGIPKQLLKNFSNIP
ENATGDMFGQIYEYFLGNFALSEGQGGGEFFTPRSVVRLMVEIIEPHQGT
VFDPACGSGGMFVQSAQFIEEQRKKLNQSAADDLFVYGQEKTLETVKLAK
MNIAVNGLRGDVRQTNTYYEDPFGSFGKFDYVLANPPFNVDDVNLSRVEI
DARFNTYGIPRNKTKGKKQEQGNETVPNANYLWINLFATSLKPKGRAALV
MANSASDARHSEADIRQKLIEENLIYGMLTLPSNMFYTVTLPATLWFFDR
GKTDDKILFIDARNIFTQVDRSHREFSTEQISNIAIISHLRRGRSHRFIE
LINNYFQQGMVKLRENQAQVQQVSQQLITVLNDGMDDIKAREAAVDFLNL
WDDLPDLEIQYQGYLDKYNFPEINIEIQNQAQQELSAAFKPFFDDIHLGL
KQLDKTIRAHETALAEKAKEEGKRGQIDKQVKTLKATLETLHTDVKSAES
FFIHIRWLQERFPKAEYEDVTGLCKLATPADVKEQDYSLNPGRYVGVVIE
EDGKTEEEFIEEILGWNTELEKLNQEAIKLGDVIRHNIQQLVGE
>Ava_2862 Protein of unknown function DUF214
MNFLESMQMAGKTLLSNKLRSALTMLGIVIGNASVIAMIGIGEGGQRFVQ
QQLESLGPNVLFIIPGNQATQRISNELPKTLVLGDAEAIATQVPTIAAVT
VELNSRQVVTYSNRNTNVNIIGTNPNFLRVRDFNVDRGRFFTDIDMKRSN
QVAVLGAKLAGRLFGNTNPVGQQLRIKNASFQVIGVLEAKGSNLGVDYDD
AAMVPIITTANRIVGRTSPYGLEVTFIVASAKNAESVDAAVFQITNLLRQ
RHKITGEDDFTIRTQKDALQTVGQISSALTIMLAAIAGISLFVGGIGIMN
IMLVSVTERTQEIGLRKAIGATEQDILLQFIIESVIVSAIGGLVGTGVGV
GGIMLVAALTPLEAAISPVAIATAVGISGAIGLFFGVVPARRAAKLDPIV
ALRSA
>Ava_3273 conserved hypothetical protein
MSEAIDKKSLSERDICTKYITPALTSRGWNINTQIREEVTLTKGRVIVRG
KLASRGEQKRADYVLYHKPGVPLAVIEAKDNNHSVSAGMQQAIATGELID
VPFIFSSNGDAFMMCDCTISEGQREREIPLDQFPTPQELWQKYCDLKGIN
SDIQPIVAQDYYPSPDKKQPRYYQQIAINRTIEAIAKGENRILLVMATGT
GKTFTAFQIIWRLWKSGAKKRILFLADRNILVDQTRVNDFKPFGSKMTKI
KQRQIDTSYEIYLSLYQAVTGNEEAKNIYRQFSPGFFDLIIIDECHRGSA
SEDSAWRDILEYFSSATQIGLTATPRETEEVSNSLYFGESIFTYSLKQGI
EDGFLAPYKVIRIDFDKDLSGWKPKPGQRDKYGKEIPDQIFNQRDFDRTL
VLEKRTELVARIISDYLKSSDRFAKTIIFCETTDHAERMRVALVNENADL
MAESSRYIMRITGDDAQGKAELDNFIDPESKYPTIVTTSELLTTGVDAKT
CKLIVLDQRILSMTKFKQIVGRGTRIDEDYGKMFFTIIDFKKATQLFADP
DFDGEPVQIYQPKPVDPIVPPDNGDDEVVIDGEITRKQKREKYVIADEEV
AVAFIREQYHGKDGKLITESIKDYTRKTVSQEYASLDAFLKKWHSSEQKQ
AIIQELQEMGIPLEALEQEIGKDFDPLDLICHVVFDQPPLTRKERANNVR
KRNYFSKYSEQARKVIDALLDKYADEGIEDIEKLDVLKVHPFDKVGTPIE
IIQLFGSRKEYLNVLQQLKTQLYEIA
>Ava_4561 HNH endonuclease
MSKTPRIRIPPEVRQYVFQRDKFQCQSCGKTGLEADLTIDHIIPLARGGQ
NDMSNLHTLCFDCNRRKTDKLDSRFRRHFEI
>Ava_0622 ABC transporter, transmembrane region
MLNLFKLRKNYPCVLQLSEEDCGAACIVSICRQHGRFLSMNKSREAVGTG
QLGTTLLGLKRGSENLGFNARAVKASPAILDRIKEIQLPAIIHWRGYHWV
VLYGKKGSKYIIADPAVGIRYIHREELTAAWNGVMLLMEPDHQRFSQQPH
DKPQPGFTRFLQRILPYHGLLSQVFMINIVLGVLALGSPVLIQILTDDVL
VRGDTQLLAVIAIAVIIMNLFSSGMQVLESTMIAHFSQRLQLGLVLEFGR
RILQLPLTYYEARRSGEITSRLRDINEINQLVSQVVVLLPSQFFIAVISF
GLMLFYSWQLALAVILIGALMSLATLPLLPVLQQKTRSLLVLGSENQGVL
VETFKGAQVLKTTNAAPQFWDELQNRFGRLANLTFSTIQIGIINNTIAKF
LSAIGGVVLLGLGSILVIQGKLSIGQMLAINVLQVNVLTLISSLVGLVDE
YFRSQTAISRLLEVIDATPEVDNTSQKPFAQISSDADIRFSHINFHHPGR
VDLLEDFSLKLPGGQIIALIGKSGCGKSSLAKLMAGLYQPNSGNIRIGFY
NIQDIALDCLRQQVVYVPQEPHFWSRSILENFRLGSPHISFEEVVTACQI
ADADSFISQLPNKYQTVLGEFGANLSGGQKQRLAIARGILNNPPVLILDE
ATAGLDPVSETQVLDRLLESRQGKTTILITHRPSVVHRADWIVLLDQGKI
QLQGTLEDFLSQQGEHLKFLSL
>Ava_2859 Protein of unknown function DUF214
MFKGFYKKNNTRTVPFLEILLMAAETLWSNKLRTGLTMLGVIIGIASVIA
ITSVGQGVQKSVEQQIQALGTDVIQILAGAPRSGNVRQGLGSTSTLTWED
AKAIAQQAPSAEIVSAYLQRNAQVVYGGENTSTTIYGTDLNYPEARNTHP
QEGRYFTQQELDSSAQVAVIGPTVQRTLFGQGGTPIGEKIRIQGEAYDVI
GITEPKGSQGPMDRDDQIFIPLTSMSKRLVGNNALTGVSVSGILVKSSNQ
EQLEAAQFQVTNILRLRHNIYPPQADDFRLTNQADIVSTFTNVVGLFTIM
VVAIAGISLVVGGIGIANIMLVSVVERTREIGIRKAVGATNSAILNQFLA
EAIVISIVGGGIGIGGGILIAFASATIFKFPFVISMISIIVGFGLSLTVG
LIAGVIPARNASKLDPITALRSD
>Ava_3502 Type I site-specific deoxyribonuclease HsdR
MPNFISEDDIEQAVLAKLKQQGFKLLNCFTTNPDDLNDRSNRTDKSEVIF
SDRLKAAAIRLNPNLPAEAIAQGLETLTNKRQLMSPIAANREIDRLIRDG
IPIEYENAQGRSEHGKVRLIDFNDLSHNGNNEYLAVSQLWIKGERNYRRP
DILLYINGLPLVFIELKNSNVKLQTAFDDNLSNYKKDIPQLFLTNAFCIL
SNALETKIGSFTAEWEHFFNWLRVEDEKEKIDRQQIQESGTSLELAIDGL
CHPSKLLDYIENFILYHKETQKIIAQNHQFIGVNRAIDAFDHREVKQGKL
GVFWHTQGSGKSFSMIFYARKIFRKLTGNFTFVIITDRDDLDGQIYRNFL
NTETVKEKEAARPKNSKQLREFLSLNKRIVFTLIQKFRYEKGEEYPILSD
RNDIIVIVDEAHRTQYKTLAENMRAGLPNANYLAFTGTPLLGKKRKTNEW
FGDYVSEYNFSQSVDDGATVPLFYQKRVPEVLIQNEDLSEEFYQILEDEN
LDDTQQAKLERKFARETEVIKRDDRLETIAKDIVYHFPRRGYLGKGLVVS
LDKFTAVKMYDKVQYHWKAEIKNLVGRIKKSSNDIEKIRLKKILDFMRET
EMAVVISLEGSDSEVEKFAKQGLDIKPHRERMNTVDAQGHDIEYQFKDEE
NSLRLVFVCAMWLTGFDAPTLSTLYLDKPMKDHTLMQTIARANRITSYQI
HNVTKTNGEIIDYYNVFRNMKQALADYALGDDGDKEDSPIQEKSNLFELL
DDAIAQGLNFCRELGIDLESILKIQETFEKLGQFNQFADTLLQKDEWRKG
FFVYQNTITSLYEACKPEIIKKPRPLVFIFQYLRGVIDSIIERKDIDHAS
LKIAELLDESVVADNQGITTKEYSAEYNIIQTGQVWDLSKINFEQLKAEF
SYKPYKNIEITDLRSFIEDKLNKMIQQNTTRTDFAQRLQAIIDKYNAGGS
SIDNYYEALVNFTENLKAEAERHIREGLTEDELELFDLLKKDKMTAEETQ
KVKLAAQSLLHRLIAEQPKVLVQDWYKDMQSQRRVQSVVEAVLDQNLPES
YDRALFKFKCDTVFDLMYDHASKGSKWAG
>Ava_2250 DevC protein
MKRKIPLAWLQLSREKARMLVAIAGIAFADVLMFLQLGIREALFDGAVQL
HNSLEGEIVLVSSRYKSLFSQQRFSQRRLYQAMGFTGVQSVSPIYVDPLP
WKNPDNQETCNIYVIAFNPEEKVLNLAGVQENLTKLREPDTVLFDLGSRK
EFGQIVPKFQTRGTFTTEINNRQIKTVGLFKLGTSFGINGNLITSDVNFF
RLFNQRRQPGLIDLGLIKLEPGANINWVLANLKANLPDDINILTKQEFAN
QERSYWNSSTPVGFTFTLGAIIGFMVGAVIVYQILYSDVSDHLPEYATLK
AIGFKNRYLLIIVFQEALILAAIGFIPGIAISQGLYMITRQATLLPIMMT
LDRAVFIFMITTLMCSISASLAIRKLQAADPADIF
>Ava_1217 Acriflavin resistance protein
MVKLTSSKSARQRFNFSRWAIEYSWLTVSFWIAVAVAGALAFSSLKYALF
PDITFPVVVVNATAPLKTAVDTEAKLTIPIEESLRSLEGLDNLRSSSYPG
QAAVSLAFSVGTNLETSTSKVEAALKQLNLPQGASYKTIPLNLNESAAVS
YAIESNSRNLADLTKLAQDQITPAIAKLPGVLKVSLLGAPTASPPLNAAN
DSLAALSQGAGTLVRFNGQSALAFQVIKRGNANTLEVVSRVEQEVQKLRA
NLPDVKLTLAATQAEYIRHATKSTIDALIEAIVLSIVVIYPFLWNWRATF
ISALAIPTSLLATFIVMAIFGFNLETITLLALALVIGSVIDDAILDVENI
MRHIEEGESPRQAAYSATDEIGLTVVATTAAAVAVFLPIGLMGGVVGQFF
KPFGITVSASYIASTLVARTLSPVLATYWLKPVTKTPQRKEANIWGKFTQ
FYRNLLHWSLSHRKTVVALAVLSFVAGIALIPFIPKGFIPKLDRGEFNIT
YTAPLPKIPDLAALQLQARQRSNITQSPVPNPQFPIPNPLNDSLEVAKKL
EEVVRKYPDVETVFTTVGSREGEPNKGILYVKLKEDRKIQTAELKDQLRS
NLPNLPGVTTSVEDIQFVDTGGQKPLQVALSGNDLQALNQAAKKIKERIE
KIPGFADVTVTGETNTQDQVLQIERLNNQRVAYISANLGQDLSLGNATDK
IVAEAQPILPAGITLNLGGDSARQSEVFGSFASTLALSALCIIVVLVLLF
KSWIDPIVIGVSLPLSIVGAMLALLFTKSDFGMISLIGFVFLLGLANKNA
IVLVDYINQLRQAGLSRTEAILKAGPVRLRPIIMTTISTLLGMLPIALGL
GAGSELRSPMAVAIAGGLVTSTILSLIVIPVVYAILDDWFPRFAHKERN
>Ava_4230 ABC transporter-like
MIEVEHLSKIYGSTPAITDVTFSVEPGEIVGFLGPNGAGKTTTMRILAGY
LPASSGTAKIAGFDVHENSLAVRQRIGYLPETPPLYTDMTVEGFLHFVAR
IKGVSAGDRSLKVNAAIKRCNLEDRRKVIIRKLSKGYRQRVGIAQAIVHD
PPAIILDEPTVGLDPRQIIDVRNLIKSLAGTHTVILSTHILPEVSMTCSR
VAIINRGKVVATNTPENLMTQLTGGSGYEIEIEGELALAKQVLQKVPGVS
LVESIPGHHLPRENRAYLRVLSQPGSDAGKDIATSLISSGFGLHEMRRVS
ATLEDVFLQLTTEEKNLTSLKDSATKEGEAA
>Ava_1128 ABC transporter, transmembrane region
MKLQGQIYIINGNEPILLNDSSGVWVVQSGSVALFAVTVKDGVIDGTRRY
LCSISQGEALFGTVHQQSQMLAVPIGEVELLLLHPECFRELGATANAWIE
NWLMQLGSVLSQIPTPKIQVKAAGQGRFSLNNGQTFQPATGVSCWVELQE
GNVCFLGCEELRLTTATTFPLNDKIWLTAVGGVQLTTHSSSEYENPDILL
AGLSQLHTQILSCVALLDEQEAQAELTRLQERQRLNRRVTAEALGELSST
LNSQDGNFFLEGTPLLMAAGAVGRAMGIKIRPPLSSENLQRVKEPLEAIV
RASRIRMRRVLLRDNWWLKDAGALVAYTKENQPVALLPVAGNRYEMFDPV
NHSRVGVDERVAATLAPMAYMFYRSLPDKVLQAIDIIRFTLQGHGQDLLQ
IVLTGIFITLLGMITPYATSIIIDNAIPDSDRSLLLQIGLGLLVAALGTG
IFQLAQGFALLRMETSGDASTQAGVWDRLLNLPVSFFRQYTTGDLLSRIS
SVSAIRRQLSGKTLVDFITSIFALFYLGQLFYYNYRLALIAVASAVVAIA
FTTISGMLLLSKVRPLLEVRGSIFGQTVQLINGISKLRIAGAEERAFAAW
SKNYARQIKLELSTQLVEDFVVLFNTVIPIITSGVLFWFTIQLLEEDQTS
GGVVFSLGTFLAFNTAFSNFTRGTTNLSNTVTQILQIIPQWQRTQPILAT
VPEVNITKADPGKLTGKITVDHMTFRYRHDGLLTLDDISISAEPGEYIAL
VGSSGSGKSTILRLLLGFETPQAGSIYYDGQDLSGLDVDAVRRQLGVVLQ
NGQLSSASIFENIAGGAQITLDEAWEAARMSGFADDIKAMPMQMHTVVSE
GGGNISGGQRQRLLIARALALKPRILLFDEATSALDNRTQAIVSESLDKL
QVTRIAIAHRLSTIRNAHRIYVLQAGRLVQQGTFSELANAEGIFAQLMAR
QMT
>Ava_B0091 restriction endonuclease
MPIPDYQAIMLPLLKFTTDQKEHSLQETIDALADNFQLTEDERKELLPSG
RQPTFNNRVGWARTYLKKAGLVESTKRGYFRITDKGIDTIKTNPVEINAK
FLRQFPEFLEFQNYTQQSEESASNGSGNEINTTRTPEEDVELAIQKLTKE
LASDLLQIIKNSSPAFFEKLVVDLLVKMGYGGTRKDAGKTVGRSGDGGID
GIINEDRLGLDVIYIQAKRWENSVGRPEIQKFAGALQGFRAKKGMFITTS
TFTNEAKDYVSRIDSKIVLIDGEMLTQLMIENNVGVTPFTVYEAKKVDSD
YFTDS
>Ava_4888 conserved hypothetical protein
MNNETQQTDTSGQVPPTPLRCITGAGISGGMGYALYLLMISIATTFAKKP
IHSDNQLVISLTSAVRTLVVGIVALGTGIFAIVTIGLLALAVQLLVQQLI
KPKNN
>Ava_2435 ABC transporter, transmembrane region
MLKPKKSAVPGLWEVLVYFWPDIRPQYGLLLVSAIALIADVGLRVLEPWP
LKFVFDYVLLRGDRVNTLPLIANLEPITLLTFSAVAVLMITGLRAFAAYG
STVGLAIVGSRVMAKVRNRLYCHLQDLSLAYHTKARSGDLIIRVSSDASR
LQEIMITAALPLVVSILSLFGMIGVMFWMNLSLTLLSLITLPFFWLVTNR
LSQRIKDSSLKQRQQEGAVAATAAESIAAIKLVKALSLQDAFARVFAQQN
QSSLKESVKTQRLAAHLERTVDAVIAMGTAIVLWYGSWLALRDALTPGDV
LVFLTYLKNAFKPVQNFAKYTGRLAKAAASGERILDVLNQKPDIHDLPDA
VPASIFRGAVRFDRVHFAYDSGRVLLEDINLNIQSGQQVAIVGTSGGGKS
TLVSLLLRLYDPTSGRVMIDGRDIREYTLASFRSQISVVLQDSLLFAASV
KENIAYGIAGVSDAEIEAAARLAHAHDFIQALPQGYDTLVGERGATLSGG
QRQRIAIARAAIRQAPILILDEPTTGLDKESEKAVIDALQRLSRNRTTFL
ITHDLDFATRADMIIYLEHGRIVEQGSHVELLNKNGRYAALYEVQASLRV
>Ava_1234 ABC transporter-like
MQSINTSEPVISIQNLDHYFGSGQLRKQVLFNINLEINAGEIVIMTGPSG
SGKTTLLTLVGGLRSAQSGNLRILGSELCGASSKQLTQARRNNGYIFQAH
NLHGSLTALQNVRMGLELQPGISTQEMLTRSTAMLEEVGLGNRLNYYPDN
LSGGQKQRVAIARALVSQPKIVLADEPTAALDKQSGRDVVELMQKLAKEH
HCTILLVTHDNRILDIADRIVYMEDGHLVKDEVSVNK
>Ava_4768 conserved hypothetical protein
MQTKQKVTLYLSPELHKKLKIRSAIDSEPMSELAERALDFYLTNSDLVDE
LEAAAYGRTHKVYSCPNCESSVVLRDGELVALGNQPGLIGQDHLPIDEMA
EAETHPKGEEELVPC
>Ava_4926 Twin-arginine translocation pathway signal
MNIKRRQFLKTCGLATVATQIPLLTAQGEQWSSLQDTTPSLRLRRSTSNA
RSLSNTIIKPQRLQVGDTVGLIAPAGTFEPRYIEVVQQHLTNLGLKAKVG
RHILDRYGYLAGRDADRAQDVNDMFVDDSVQAILAMRGGWGCNRILPLLN
YPLIRSHAKILMGYSDITSLLLAINARSRILTFHGPVATSTWTPFMLEYL
KRILFNAEAVTLENTDSPEGKVQTITPGKAQGQLVGGNLSVLSAMVGSPY
LPGWQNRILFLEDVNEDVYRVDRMLTQLKNAGILYRISGFIFGQCTDCKP
TNEKSQTLIEVLQDHITPLKIPSWYGAMIGHIQDKFILPIGANVEIDADA
GTIELLEAAVN
>Ava_1688 conserved hypothetical protein
MSEMTIFTNFLRSLVLTIIFSFVAPLCLIGGVLLFLSLGGYVPLVGGLTT
AIADGIFNFLIIFGSGSALHGILVIGLTCSFVGALFDTYVYYRYQILRLD
S
>Ava_2963 ABC transporter-like
MVKELAIRTRGLTKQFERHIAVNDVDLEIQMGEVYGLIGPNGAGKTTLIR
MLAAAEEQTTGEIYINGEHLRLDKSNSTLKRHLGYLPDDYPLYEDLTVWD
YLDYFARLYRLREPRRTQRLHEVLELIQLENKRKSQISTLSRGMKQRLSL
ARTIIHEPILLLLDEPVSGLDPIARMQFRQIIKALQEAGMTILISSHVLS
DLAELCTSVGIMELGFLVESASLQALYQRLSQQQIMLSTSGSLESLMSEL
KNYPLVEQCEKIPGKNSIRVNFAGTQDDCAELLRSLILSGIPITNFHCTQ
EDLESIFLKLGHKQAS
>Ava_B0057 HNH endonuclease
MCKVFVINKEKRPLNPIHPAQARQLLRSGKAAVFKRFPFTIIVKESNVNT
NVSPLRLKLDPGAKTTGIAIINDANDEVVFAAELKHRGFAIRDAITSRRQ
LRRSRRNRKTRYRQPRFLNRTKPEGWLAPSLQSRVENIKTWVSKLRKVAP
ITAISQELVKFDMQLIRRPDIQGKEYQQGTLAGFETRQYLLEKWNRECAY
CGIKDVPLQIEHIHPKSKGGSNSITNLTLSCEKCNLRKGNQDIRDYLEKD
KPRLEKILALTKKPLADAAAVNATRFALLYALKSTGLPIETGSGGLTKFN
RTQQALNKSHWLDACCVGASTPILKIKGIKPLLITANGHGTRQSCRTDKY
GLPVRHCSRTKFHFGFQTGDIVKAVVTKGKKVGTYVGRIATRATGSFNIS
TAKGLIQGISHKYCKTIHKKDGYAYGI
>Ava_1326 conserved hypothetical protein
MVKDREIQAHKEWLGFLQPVGLVVSPTALNNAQMSVNRNVVELQQRLSEI
VSRNSFDDSSNYTCVISDFPTFTVEILGWQPTDLVESPEDLTVSLPEYGE
ILQPTYTVPDPDKGGWLMLVQVISTGTDFDRVSENIKSTGWHANPQGKFE
RLLREKEIPVGILCNGTELRLVYAPRGESSGHLTFPVQAMCEVSGRLILG
AMQMLLEEQRVFNAPTDRRLVALLQNSRKYQNEVSTKLSEQVLDALWELL
RGFQAANDHAKGLLLDDIAQNDPQHIYGGLITVLLRLVFLLYAEDEGLMP
QGSIYTRNYSVTGLYERLREDAGNYPDTMEQRYGAWAWLLSLFRLVYDGG
CHADLYLPARHGQLFDPDEYAFLEGRSRHTTYKEWDLIEPPRVSDSVVHE
VLRALLVLDGERLSYRSLDVEQIGSVYEAATGYEVKKATSQSIGLWSKPK
SAKASITVVVSVDEVLKTKANDRAKYLKEVAGCEISGKSLTDLKQATTAE
DLIAALGRKISPQTPTLLPVGSLYLQPGEERRRSGTHYTPRALTEPIVKE
TLRPVLEALGERPTPEQILALKVCDLAVGSGAFLVEACRQLAEKLVEAWN
QHGMISEVPSDEEPLLYGRRLVAQRCLYGVDKNPFAVNLAKLSLWLVTLA
KKHPFTFLDHALKCGDSLVGLTRDQLVKFNWEKDTTYDDKELLLFNEQLN
KVKFNRDEIQSLDDENYDAKRDFYEATEELLHDARLKGDLVIASFFAAEK
DKARKEERDGLFQKYFKWRRNPDESAEVLSISKKLRQADKPVKPFNWETE
FPEVFDRENPGFDAIVGNPPFLGGKRISTVLGDGYRDWLPIVNPEANSNS
DLVAHFFRRAFTLLRNNGCFGLIATNTIAQGDTRDTGLKYICNHDGTIYN
AQKRLKWAGDAAVVVSVVNIQKGIYVGKKILNGIEVPLISAFLFHTGGNE
APQTLIANANKSFIGSDLQGMGFTFDDTKSDTTSIAEMHRLTTKNPKNAE
VIFPYIGGSEINTRPTHDYHRYVINFGDMDEEKAWEWEELMKILEEKVRP
ERLRKAKELAQYPWWRFWRTRQKLYDAITSLERVLVCSRVNPNCSFTFLP
PNLVYAESLVIFALSKYSAFGILQSSTHELWARFFSSTAMDLLRYSCSDC
FETFPFPQNWETNSTLETIGKEYYEYRAALMVRNNQGLTDTYNRFHDPDE
YDPEILKLRELHTAMDKAVLNAYGWSDIPTDCDFILDYEEEEDTENSSGR
QKKKPWRYRWREEIHDEVLARLLDLNQKRAEAEILGGKGADKGKGKGGKN
KSNQRKSKKVIENAPAIPGII
>Ava_0192 ABC-2
MSVTPKSDINWQPATSPQANVNTAPNFFGELVQETLALTRRLFIQLQRRP
STLLAGIIQPVMWLVLFGALFQNAPKGLFGSTTNYGQFLAAGVIVFTAFA
GALNAGLPVMFDREFGFLNRLLVAPLASRFSIVFASAIFIVSQSLLQAAV
IVGAAAFLGAGLPDVAGLGAIALIVFLLALGVTAISLGLAFALPGHIELI
AVIFVTNLPLLFASTALAPLSFMPQWLQVVATLNPLSYAIEPIRYLYLHS
HWGLGDVVMQAPWGDVTFGGALLILFSFAFVALLSIQPQLRRTLA
>Ava_1188 Cyclic nucleotide-regulated ABC bacteriocin/lantibiotic exporters
MTYIKSAFQEFLVTIEGFDQLPSEELTQILDNLQPFRYRIGQKIIGKERT
PERVTIIYEGQVRLLGFDPQTQVPTTLKLMKPGEIIGEIGLLRDVACETA
IASADEVIGLTLNATDYLRLLESYPGFAHARQNQSYIIEVFDVLSSQLAN
QANVISNLDELAAQALENAKIDYLPPGRNFFHQLDSESIWFVSGGTVTNY
PIGSRLEPSDGNRVIEVQGESPARLVGLEPLDLLFLENDYHQGGELTVYD
SSPKITEALDIPYASEEELSQSSSVPSNAKPRQKFPFVRGKGELNSTFAC
FQMLTKHLQIPFRKEVVRRILNEQMKRQGTISFPACAYLSELIGLKANLV
DLPAAAITRVPTPALVRYGDGYAVLYAADANNVVLGVPSQGIVRCKPAQI
LEHLNIVEDSYPPQIRVLLLSATKETPQERFGLRWFIPYLSRYRRVLIEV
FIASFFVQLAALANPLVIQLIIDKVIVQNSISTLNVLGVLLLAVGVFEAV
LTTLRTYLFVDTTNRIDMGLGSEIIDHLLRLPLRYFEKRPVGELATRINE
LENIRQFLTGTALTVGLDAVFSVVYIIVMLFYSWQLTLVGLGTIPIFIVI
TLIASPTVSRQLRSKAERNSETQSYLVEVMSGIQTVKAQNIELRSRFSWQ
ERYARYVAAGFKNVITSTLANSTSQFLNKLSSLLVLWVGSYLVLQGELTL
GELIAFRIISGYVTSPILRLAQLWQSFQETALSLERLSDIVDTPQEAEID
RYNIPLPEIQGSVKYENISFRFAPSGPLQLSNVNLEIPSGKFIGIVGQSG
SGKSTMMKLLLRLYDVESGRILIDGYDIAKVELYSLRRQVGVVPQETLLF
DGTVQENIALTNPDASTDEIIEAARVAAAHEFIMSLPNGYNTRVGERGAG
LSGGQRQRIAIARSVLQRPKLLVLDEATSALDYPTERQVCLNLAKAFQGS
TVFFITHRLNTVSHADMIVVMDAGKVIEQGSHQELMAAKGHYFYLYQQQE
VNL
>Ava_3838 Hydrophobe/amphiphile efflux-1 HAE1
MFVDFFIRRPVFTSVCAIIILLVGAISIPTLPTDRYPEISPTQIVVNANY
TGASAEVVENTVTSILERQINGVQGMKYMTSSSSNDGTSTITVTFDPSRD
KDIAAVDVQNRVSIAQPQLPEAVQRTGVTVSKQSNNILLAMGLYSEQQEY
DTVFLSNYADQYIVDALKRLDGVGEARIFGERRYAMRLWLDPNRLTSRKL
TAQDVIDAINEQNIQVGVGQIGQQPSLPDQMYQIDLQARGRLSEATEFAD
MVIKTGTDGTLIKLKDVGRAELGAENYSSFLRFRGNEGVGIGIFPTPGSN
ALEVSKAVKAEMARLAQSFPPGLKYQVAFDTTLFVEESLAEVVKTLIEAL
ILVVLVIFLFLQDWRTTLIPVITIPLTLIGTFAFIKVFGFSINTLTLFGL
TLATGLVVDDAIIVVENISRLIEEEGMSPRQAASESMRELFGAVIATSLV
LMAVFVPVAFFPGTTGQIYKQFALTIAFSMAISTFLALTLTPSLSALLLR
RGQRPRGWLGKIFHQINRFLDWMRRGYERSLNILVKVRAIVVLLFLASIA
LTGWVYLSVPTAFIPDEDQGYFITIIQGPEGVSLNYTSNVMAQVEKEILK
LPEVTGTFAIGGFSFSGNSANSGVIFTTLQPWDERQQPGQSAPEIIGKLA
GVFANITEARIFPVSPPPINGLGNFGGFQFELQDRAGNSGLDNLLQVMGQ
IMMKGNQTPGLQGVFSTFSANTPQMLIDIDRNKVKALQVNVDDVFNTLQS
YLGSRYVNDFNFQQRTYRVYVQADAPFRSNPEDIGKLYVRSANDQMISLS
NLVKITPATGAQTINHYNLFRSITINGAAAPGYSSGQATTAMEKLAKEVL
PASMGYEWSGITAEEQESGGQAPVIFGLGLVFVFLVLAAQYENYVDPLII
MLSVPLAILGALSAQWLRGLSNDVFCQVGLVMLIGLASKNAILIVEFANQ
LRERGLPIIKATVQASQERLRPILMTSLSFILGVWPLINPIGAGAASRKS
LGTAVAGGMIVSTVLSLFVVPILYIVISKIRDRFRPKPPHIPLDSTRDDK
IPSTSHR
>Ava_B0097 HNH endonuclease
MSQDLYPNNWKEIATALKAASNWRCAKCGRVCLRPGEKPDNLTFSERKAH
TLQVHHWNRDPSDNRLENLVCLCSGCHLSYHCFSRGNVSPGQLSLFAEQK
VS
>Ava_B0307 Type III restriction enzyme, res subunit
MQFDNLLSRADDGTLQVLLGNAAVRLIKLLDPSLVTPSRLREILMELHTP
ASLLLTKDSRAMLLDLLRPEQAKILATIMQVPLTGDIFETLKKTSIRHGS
NRERALFDFFELELPQPEDSVQSSSLELAVSNYPLFAHQRIAARKVKNYF
KQEPRRVLLHMPTGSGKTRTAMNIIADHLRSVEPTIVVWLAYSEELCEQA
ATEFQKAWQCLGDRQVSLYRFWGEHEIDVDKLEDGIVVAGLSKVYNRTKQ
SIQFINRLGKVSSLVIIDEAHQAIAETYKLVLDALVVPYENTALLGLTAT
PGRTWSDINVDTELSEFFAKNKVTLEVSGYSNPVDYLISEEYLAKPNFRS
LFYKNGLKLTQKDLERIQQELEIPQHILEQLADDEQRNLSIIIEVEELAK
RHQRILIFGISIKHSKLLATVLRARGLQANVVTGDTPLLERTRLINSFKD
DSDETKIICNYGVLTTGFDAPRTSAAVIARPTKSLVLYSQMVGRAIRGVK
AGGNVTAEIVTVVDSALRGFGSLEEAFSNWEDVWHKEKI
>Ava_3017 ABC transporter, transmembrane region
MAIASPSHRVLQRRRHSAHPLQRLFDYGYQYRQQMLLAVGCSILNKLFDL
APPALIGMAVDVVVKQQDSIIAQLGIKDIFGQFLIVALLTVITWILESFF
EYRYRVLWRNLAQNIQHNLRLDAYSHLQELELAYFEERSTGGLMSILSDD
VNQLERFLDVGANDIIQVVTTIVVVGGAFFILAPSVAWMAILPMPFILWG
SVAFQKLLAPRYADVREKVGLLNGRLSNNLSGITTIKSFTAEEYEKGRLE
IDSSAYRQSNTRAIALSAAFIPLIRMLILVGFTSLLLFGGMATVAGRMSV
GAYSSLVFLVQLLLWPLTRLGETFDLYQRAMASTNRVMELLDTPITAYTG
NIALPVEEVRGAVEFNNVTFAYKDRLPVVKHLSLQIPAGNTIAIVGSTGS
GKSTLVKLLLRLYEVQAGKITLDGINIEDLKLRDLRRSMGLVSQDVFLFH
GTVAENIAYGTFDATEQEIITAAKIAEAHEFISHLPQGYETIVGERGQKL
SGGQRQRIAIARAVLKNPPILILDEATSAVDNETEAAIQRSLERITINRT
TIAIAHRLSTIRNADCIYVMEHGQLVESGTHEALLDKDGIYANLWRVQSG
LK
>Ava_3286 ABC transporter-like
MQSFTDTPDSQLTTKNTPPVVMTSDLRKVYRTGFWMNQKVVSLKGCSLTV
YQGETFGLLGPNGAGKTTLLKLLLGIIRPSGGQGLLLGQPLGDRHIKQRV
GYLSENPYLYEYLTGWEFLELAAGLFAIPAAVQRQRIPELLDLVGLSVAD
AQKKQMRRYSKGMLQRVGMAQALINDPELIFLDEPMSGLDPLGRYRMREI
ILSLKAAGKTIFFNSHILSEVEQICDRIAILSQGELICSGSLDELLGSQN
TYHVKGQNGDWEILKKWLANLVYEPDGYWQGTLQEDYYDFLASVRLMGGR
IISMNLSRQSLEEFFIKQIQKQDTSLHDDK
>Ava_3639 DevC protein
MLSQMFRKTPLAWRQLMKEKTRLAVAVAGITFADMLMFIQLGFESALFDA
AVKPHRNLQADLVLINPQFQTLFSVKSFSRERLYQTLGYEGVQSVTPLYI
GTGQWRNPETRQDRAILVWGIDPATSAFTFPEIRKNQDQIKQLNQVLFDQ
AGRPEYGAVGDIFKKTNSFQTELNNIGVNVSGVFSNGASFAADGNVIASD
STFLRLFPERKPERIEVGLITLKPGVDKEKVRSQLAAGLPNDVKVLTPEG
FAQTEKEYWANGTGIGFIFGLGVGVGFIVGIVIVYQILYSDVSDHLPEYA
TLKAMGYTDRYLLVVLLQEALLLAFLGYLPAYILSFGLYQITYAATMLPI
AMKLERAITVFILTIIMCTASGAIAMRKLRSADPADVF