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# Streptococcus pyogenes MGAS10394, MGAS10394

>M6_Spy1013 Phage endonuclease
MVAFYYGGQGMRPQKLTIAGGRRTTVDYDDRSAEYRDYNRNRWKYDKQVK
QFYNSRIWRETSKQVLLQNDYICAMCGGEATMTDHIVSVKQDWNKRLDLN
NLQASCKACNDSKAIRERRKNNY
>M6_Spy1225 HNH endonuclease family protein
MSQLRADKKGTHRVAFEKNKRKLLKTTNLCGICGKPVDKTLKYPHPLSAA
IDHIVPIAKGGHPSALENLQLTHWQCNRQKSDKLFANQASNEPKTIGNRN
LPQSRDWSSFTLKK
>M6_Spy0228 Multidrug resistance ABC transporter ATP-binding and permease protein
MMKTARFFWFYFKRYRFSFTVIAVAVILATYLQVKAPVFLGESLTELGKI
GQAYYVAKMSGQTHFSPDLSAFNAVMFKLLMTYFFTVLANLIYSFLLTRV
VSHSTNRMRKGLFGKLERLTVAFFDRHKDGEILSRFTSDLDNIQNSLNQS
LVQVVTNIALYIGLVWMMFRQDSRLALLTIASTPVALIFLVINIRLARKY
TNIQQQEVSALNAFMDETISGQKAIIVQGVQEDTMTAFLKHNERVRQATF
KRRLFSGQLFPVMNGMSLINTAIVIFVGSTIVLSDKSMPAAAALGLVVTF
VQYSQQYYQPMMQIASSWGELQLAFTGAHRIQEMFDETEEVRPQNAPAFT
SLKEAVAINHVDFGYLPGQKVLSDVSIVAPKGKMIAVVGPTGSGKTTIMN
LINRFYDVDAGSITFDGRDIRDYDLDSLRQKVGIVLQESVLFSGTITDNI
RFGDQTISQDMVETAARATHIHDFIMSLPKGYNTYVSDDDNVFSTGQKQL
ISIARTLLTDPEVLILDEATSNVDTVTESKIQRAMEAIVAGRTSFVIAHR
LKTILNADHIIVLKDGKVIEQGNHHELLHQKGFYAELYHNQFVFE
>M6_Spy0532 Factor essential for expression of methicillin resistance
MGIKLMYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERISF
YENGVQVAAAACLIRKLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTF
GKSKRALFVKIDPSLVIKQTLEGKESKENDVTLSIIAFLKKLGVEWSGRT
KELEDTIQPRIQANIYAKDFDFDILPKKAKQSIRTATNKGVNVTIGGSEL
LDDFSALMKKTENRKGIILRGKSYYQKLLDIYAGQSYITMASLDLPEQKK
LLIQQLDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLAAGK
TRIPLAATLTLIYGETSENLYAGMDDNYRNYQAPLLTWYETAKEAFKRGC
RWHNLGGVENQQDGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAILTYN
LRKKLRSTTNGTN
>M6_Spy0270 Bacitracin resistance protein
MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKAFIEMFN
IVIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSIL
IAVPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKRNAQQEPAVTELARM
SYKTAFFIGCFQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIP
TMFGYSGLKAVKFLLDGHHLDFAQVLILLVASLTAFVVSLLAIRFLTDYV
KKHDFTIFGKYRIVLGSLLLIYSFFKFVF
>M6_Spy1511 ABC transporter ATP-binding protein
MTQQSMLLSIEQVNKSYGKNQVLSDISFDIYKGEICGLVGQNGAGKTTLM
RILSGLIGKDSGQIKQLQPYRMGSIIESPTLYPNMTAHDNLYYAALQLRL
ADAKERIHEVLELIGLEKVSKKKKVKDYSLGMRQRLAVGLSILDFPEFLI
LDEPINGLDPAGIKEMRQIILNLRDCYGITILISSHILSELDLVVDRYVI
MHKGKVIKSMDKAELKAQVKVQIALHTSDDQLVKNRLLELGLRVETDGQM
LLIKPTLSVMELIKIVLDLPVEIFDIYHHQVSFEHYYLDLLGKDAASPLI
>M6_Spy1146 Phage endonuclease
MGISQKPIFLGRSKMPRRPSTPCKQNGCPNLVPYGHKYCDNHKANYQLDT
KSTKAKGYNAQWNKARLRYLKVQPLCVQCKVKGRLTKATVVDHITPHRGD
QDLFWNQTNWQALCKSCHDRKTKTTDRYVEYTYRF
>M6_Spy1726 ABC transporter permease protein
MEDIIAALGSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTENTKRQL
IGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKG
VKNALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKD
FIDQKQVIYLEKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGL
TSGTEKIAYIPLHQWYNINGVVDATPEITIQTYRADDLKPVAKRVSDMLN
QTIPKSDYMFGVMNLKEFERQLDNLNKSNFVLLAGIASISLIVGGIGVMN
IMLVSVTERTREIGIKKALGARRKLILKQFLIEAVILTLLGGVIGVISGM
VSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIKASKLDPIE
ALRFE
>M6_Spy0954 Type I restriction-modification system specificity subunit
MENSIEAYLADSREKVTLGTVVDCFKGKAVSNKVVPGDVGLINLSDMGTL
GIQYHQVRTFQMDRRQLLRYLLEDGDVLIASKGTLKKVCVFHKQNRDVVA
SSNITVLRPQKLLRGYYIKFFLDSPIGQALLDAADHGKDVINLSTKELLD
IPIPVIPLVKQDYLINHYLRGLTDYHRKLNRAEQEWEYIQNEIQKGLG
>M6_Spy0585 SagH
MVLFHLIKKESLQIFRNRTALLMMVIFPILMIVILSFAFKSSFNTATTVP
KLTIRYQLEGEKTDYQKNFLAFLKVLNQKLHLEAKPSNSLEKDRQRVSEG
ALTAVLEVKKNQTIKVITNNINQQNADLINMLVKNYVDNAKTYDSIAALY
PQQLNHIRKRSVDYVKVSSIQTSKGMTSADYYAISMFTMITFYSMMSAMN
LVLSDRQQRITNRIRLTGVSPSLLVFGKLIGAMLATTVQLSLLYIFTRFV
LRVNWGTNEWMLIGITASLVYLSVAIGIGLGISIKNEAFLTVASNTIIPI
FAFLGGSYVPLTTLHSSIINQLSNISPIKWVNDSLFYLIFGGQYNPIPVT
LIVNISIGTIFIILALIGMRKQVTT
>M6_Spy0609 ABC transporter ATP-binding protein
MMSVLTFKQVIKTFQDGHHEINALKATDFSIEAGEFVAIIGPSGSGKSTF
LTIAGGLQTPSSGQLIIDGTDYTHLSEKERSRLRFKSVGFILQASNLIPF
LTVQQQLELVDHLTGSKEKAKANQLFDDLGITGLKHQLPQELSGGERQRA
AIARALYHDPALILADEPTASLDTEKAYEVVKLLAKESKEKNKAIIMVTH
DDRMLEYCDKVYRMQDGELRQER
>M6_Spy0586 SagI
MICFIKTLFVKIKRKKTSYVTFFLMPILTTLLALSLSFSNNNQAKIGILD
KDNSQISKQFIAQLKQNKKYDIFTKIKKEHIDHYLQDKSLEAVLTIDKGF
SDKVLQGKSQKLNIRSIANSEITEWVKAQTNYLLENYNIIGDVALGNEDT
FNRILQKNQQLNYGVKQVTLTDRSRSKAVSSTTTGFLLILMLGSTSVIYS
GILADKSSQLYHRLMLSNLSRFRYMLSYVCVGFVAFTIQIVIMLSLLKVF
NISFFVPTSLLLIIFFLFSLLAIGFGLLIGAITQNSQQSSQLANLIVMPT
SMLAGCLWPLSITPSYMQAIGKLLPQNWVLSAIAIFQSGGTLSQAWPYLL
ALMGTALALIIFSSLLLKPTRL
>M6_Spy0665 ABC transporter permease protein
MENWKFALSSIWGHKMRSILTMLGIIIGVAAVVIIMGLGNAMKNSVTSTF
SSKQKDIQLYFQEKGEEEDLYAGLHTHENNHEVKPEWLEQIVKDIDGIDS
YYFTNSATSTISYEKKKVDNASIIGVSKDYFNIKNYDIVAGRTLTDNDYS
NFSRIILLDTVLADDLFGEGNYKSALNKVVSLSDKDYLVIGVYKTDQTPV
SFDGLSGGAVMANTQVASEFGTKEIGSIYIHVNDIQNSMNLGNQAADMLT
NISHIKDGQYAVPDNSKIVEEINSQFSIMTTVIGSIAAISLLVGGIGVMN
IMLVSVTERTREIGLRKALGATRLKILSQFLIESVVLTVLGGLIGLLLAQ
LSVGALGNAMTLKGACISLDVALIAVLFSASIGVFFGMLPANKASKLDPI
EALRYE
>M6_Spy0010 Beta-lactamase
MRKLLAAMLMTFFLTPLPVISTEKKLIFSKNAVYQLKQDVVQSTQFYNQL
PSNPNLYQETCAYKDSDLTLPAGRLGVNQPLLIKSLVLNKESLPVFELAD
GTYVEANRQLIYDDIVLNQVDIDSYFWTQKKLRLYSAPYVLGTQTIPSSF
SFAQKVHATQMAQTNHGTYYLIDDKGWASQEDLVQFDNRMLKVQEMLLQK
YNNPNYSIFVKQLNTQTSAGINADKKMYAASISKLAPLYIVQKQLQKKKL
AENKTLTYTKDVNHFYGDYDPLGSGKISKIADNKDYRVEDLLKAVAQQSD
NVATNILGYYLCHQYDKAFRSEIKALSGIDWDMEQRLLTSRSAANMMEAI
YHQKGQIISYLSNTEFDQQRITKNITVPVAHKIGDAYDYKHDVAIVYGNT
PFILSIFTNKSNYEDITAIADDVYGILK
>M6_Spy0608 ABC transporter permease protein
MFLALNEMKQSKLRYGLIAGLLCLVAYLMFFLSGLAFGLMQENRSAVDLW
KADSVLLAKDADATLTLSQVSRAQENQITADKVAPLAQLNTVAWSVKNPK
DADKVKVSLFGIDSNSFIRPNIVKGRLFKTNKEVVLDQSLAKEEAFAIGK
DFYTSSSSQALTIVGYTQNARFSVAPVVYMNLEAFETLKYGEPLPKDKQV
VNAFITKGSLIDYPKKDFQKLDIKTFITKLPGYSAQLLTFGFMISFLVII
SAIIIGIFMYILTIQKAPIFGIMKAQGISNKTITTAVLMQTFFLSFLGSG
LGLLGTWLTSLLLPTVVPFQSNWFLYLAIFVSMICFALLGTLFSVFNIIR
IDPLKAIG
>M6_Spy1465 EcsA
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGF
LKPYQGSISIDGLTLAENAVAYRQKIGFIPETPSLYEELTLSEHINTVAM
AYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVID
PSLFILDEPFLGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCD
RFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKED
>M6_Spy1630 Type I restriction-modification system specificity subunit
MTKSKQPQYRFDSFEGEWEEKKLGEISNIVRGASPRPIQDPKWFDSKSDI
GWLRISDVTEQEGRITYLQQRISELGQEKTRVLKDPHLLLSIAATVGKPV
INYVKTGVHDGFLVFLDPKFNREFMFQWLDMFRPYWNKYGQPGSQVNLNS
EIVRNQVINLPSLPEQEAIGELFQTVDQLLQLQDQKLATLKEQKQTFLRK
MFPAQGQKVPEIRLQGFDGEWEEKKLGEISRMFSGGTPNVGIPEYYNGNI
PFIRSAEINSDQTELSITDKGLSNSSAKLVEKNTLLYALYGATSGEVGLS
RISGAINQAILAIIPEKKYSSLFIKNWLYKQKSSIIEKYLQGGQGNLSGS
IVKELTIHFPSLSEQEAIGNFFQTLDQQIAQSEEKLTELKALKQTLLNRL
FV
>M6_Spy1543 Abortive infection phage resistance protein
MCLDIIFKKSIIILTRQTPHSFKGRYVLIWGFFYIVRRVMKQPLALTWED
QIRLFEKRGLIVKADDVEKIKHISYYRIKEFAKPLEIKRQDGEEKDILYD
NIEFAEVLARYYQDKNLRIYLLHAIEKIEVSIKTKISFVLGDRYGAFGYL
NFSSWANRNKFTKYDIEKRQFRIKKNLLNTVRKSQLTELQKSINLDPDGF
PTVWLAIDLLMFGDIVSILTIMSEKNIKQICQYYSCTPEELVSWLKCLNF
IRNVCAHNSNVLDIQITTKPKLRSEWRNYIDTVKIKHNVTKPSNKLSVII
AIVVYLVNTINSKYQWRKIQSSLKALCKEDDSRAKLLGFKDYDSVKAMIN
GIKCTAFTNSKK
>M6_Spy1517 ABC transporter ATP-binding protein
MILKQDWRQVFMAKPNRSTLSLVWRLLTLMKTLLPWIILAVGFAVMGFVI
TVSIPTGIAYLGLLAIRQEVIPILALYLLIALAFLRGFVRYGEHYFGHFV
AFHSLAAFRNLIFKKLRALSPACLDSQDSGYLLKMIGEDIEALEVFFAHT
IAPICTAILSAGLMFWYFCQSSWQLALLALATYACLAIVIPIYFANILQV
LLKSQNEGRKDYLSYFLESLRSVKDLLQFQVLDEQFERLIKKSNHVNALD
RNVAQAQFLQMALTFFWLGLMILAFSYMVFDGICHDSLSFDKGLLTFIAF
TASFSPFLELGRLPLGFKRAMNAARNIFDLLDENVIVDEGTKQIDRLRSV
SFEDLSFAYPKRQELVFKDLTVTFQEKGIIGIKGESGSGKSTLVKLIMKW
YNWKTGDIFLNDRNSCLLNAAKLQDTIAYVPQTAQLFQQSIRENLTFGRQ
DISDESIWNLAEACGMKDRLLACKEGLDTIIKSPSDFSAGEGQRLELMRA
LLKDASCYIFDEPTSNLDSLNEAILLDLIKTHCQGLVFLISHRPSTLACA
DHLFCVKNGFLKEVNKK
>M6_Spy0909 UDP-N-acetylmuramoylpentapeptide-lysineN(6)-alan yltransferase
MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIY
KEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYG
KTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTM
EIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQRGVETYRASQSEL
HKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQ
YRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE
VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPKVFQDAYQDGIIW
ANMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIR
KQLKNKH
>M6_Spy0531 Factor essential for expression of methicillin resistance
MALIEISQEQFDHYCHSLVHHSFIQTSEMASLMAKRGAKPQFLGLEKDGE
LKVAAMVFSQKVAGGWRMELNAGPNTNHPEELEHFYTQLKDYAKQKDVIE
LILKPYDNYQSFDTDGIPISHPNTDLISLLTALGYKHDGLKTGYPEGEPV
WHYVKKLEGIDSSRLTHSFSKKGKALIKKANTFGIKLRQLKRDELHHFKE
ITEATSDRRDYLDKSLSYYQDFYDSFGDSCEFMVATLNFEDYLNNLKQRQ
LQLATSINKVKGDLGKNPHSEKKQNRLKELSSQFETFQVRISEALHFLEE
YGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKFYSPALLQEHAMLKAIH
KGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCYPFPIKYHF
IRLAKKLLNRY
>M6_Spy0956 ABC transporter ATP-binding protein
MEGQMAFIELKQVSKSYQVGETTVFANHEVSFEINKGELVVILGASGAGK
STVLNILGGMDTVDAGQVIIDGKDIAHYTSKALTQYRRNAIGFVFQFYNL
VPNLTAKENVELAVEIVADALDPVTILKEVGLSHRLDHFPAQLSGGEQQR
VSIARALAKNPKLLLCDEPTGALDYQTGKQILTLLQDMARTKGTTVVIVT
HNAAIAPIADRVIFMHDAQVTKTVINKEPASIETIDY
>M6_Spy0686 Hypothetical protein
MRKRCYSTSAVVLAAVTLFALSVDRGVIADSFSANQEIRYSEVTPYHVTS
VWTKGVTPPAKFTQGEDVFHAPYVAKQGWYDITKTFNGKDDLLCGAATAG
NMLHWWFDQNNEKIEAYLKKHPDKQKIMFGDQELLDVRKVINTKGDQTNS
ELFNYFRDKAFPGLSARRIGVMPDLVLDMFINGYYLNVYKTQTTDVNRTY
QEKDRRGGIFDAVFTRGDQSKLLTSRHDFKEKTLKEISDLIKKDKALGLS
HTYANVRINHVINLWGADFDSNGNLEAIYVTDSDSNASIGMKKYFVGVNS
AGKVAISAKEIKEDNIGAQVLGLFTLSTGQDSWNQTN
>M6_Spy0227 Multidrug resistance ABC transporter ATP-binding and permease protein
MLKDAILRYKWYALGSFFMVIGVVASSLLQPHYLKSVLSAVIQNNQEKIY
EVGKPLLIIALLGLMSGAINTVLAAKIAQGVSADMREKTFRKIQDFSYAN
IEAFNAGNLVVRLTNDINQIQSLVMMMFQILFRLPILFIGAFIMAVQTFP
QLWWVIVVMVILIALIMGLVMRQMGPRFGKFQRLMDKINHIAKENLRGVR
VVKSFVQEQQQYTKFKETSNDLLALNLSIGYGFSLMQPALMLVSYLAVYV
SINVVSTMVETDPTVIGNIASFMTYMMQIMFSIIMVGSMGMQVSRAFVSM
ARIRQILSTEPAMTFENEKEETISGSIVFDDVSFTYPNDDEPTLKHISFA
IEPGQMVGIVGATGSGKSTLAQLIPRLFDPQDGQILLGGKPIKTLSQTTL
RQSVSIVLQKAILFSGTIADNLRQGSAKADIDAMQKAAQIAQAKEFIDRM
NSRYESQVEERGSNLSGGQKQRLSIARGVINHPKILILDDSTSALDAKSE
KRVQEALSHKLEGTTTVIVAQKISSVVKADKILVLDQGQLIGEGTHAELV
ANNAIYREIYETQKGREE
>M6_Spy0091 Na+ driven multidrug efflux pump
MIYNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGVSIANNI
ISIYQSLFIALGAAVSSLIARSIGENNQNKQLNYMAGVLQVTLLLSVGLG
LLSVVGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVRA
QGYPKIPMQVSLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGVFL
LCQFIPIKQVAKRLMRPLDKIIFDLSLPAAGERLMMRAGDVLIIGIVVRF
GTTALAGNAIGETLTQFNYMPGLAMATATIILVARQLGGGKVTEIRYIIR
EAFILSTLMMLVMGALTYLLGPSLLPLFTQNTDAQRSAMVVLLFSLLGAP
ATAGTLVYTAVWQGLGKAKLPFYATTIGMWVIRIGLGYVIGVVWQYGLIG
VWMATVLDNTSRWFILSKQFKKYQEITFH
>M6_Spy1629 Type I restriction-modification system restriction subunit
MGNQTKTELELEKELIHLLETGESQWTYRKELKTEDALWDNFFKILAQNN
TQYLNEEPLTASEKEQIKNQLNFVNYYEAAKWLAGENGIAKVQVQREDAK
LGAIRLEVVKADNVAGGTSVYEIANQVAFSGSRDRRGDVTLLINGLPMIQ
IELKSQNHQCIEAFNQVKKYDKEGQFRGIFSTLQMFVVSNKTDTRYIAAA
KENKLNPNFLTQWVDQNNKPQKDLFAFAKEVLSIPLAHQMVMTYSVIDDD
KKALILLRPYQIHAIEAVAEASRHRKSGYIWHTTGSGKTLTSYKVARNIL
QIPAVEKSIFVIDRKDLDNQTTSAFQSYAQNDIFDVDETEDTRQLIKNLE
SSDRRVVVTTIQKLNAMISQMESYDTPKFKKLKERLAHLNVVFVVDECHR
AVTPERQRHLTNTFRNSCWYGFTGTPIFVENKRAQLGDLAQTTEQQYGKC
LHQYTVKEAIHDKVVLGFQVEYKTTIPDMPEDSIPEEAYDHEEHMLAVLN
SIINQSRKKLGFNNGIGQTFEGLLTVKSIARAQAYYDLIQKVKAGETDLV
ISKKVKEKLPDFPKVAITYSITENDNASISRQDKMTKNLEDYNHLFGTNF
TIDNLQGYNRDLNDRLARKKDKFKDRHEQLDLVIVVDRLLTGFDAPCLST
IFIDRQPMKPQHIIQAFSRTNRIFESRKHYGQVVTFQTPLRFKEAVDKAL
SLYSNGGENDVLAPSWEEEKARFFEKVTVLKNIVPDPDAFPTIESAQTAF
LKQYAKAFQAFDKLFASVQVYSDFNETLLSEVGLSDEVIDTYKGTYQNVI
AEIRKRREDDEAIPEINIDYELESVQMDDINYHYILTLIQAFVDQEQEAL
QERLNDNPMDQYIQDLAKSNPAMADSLAELWQDIQKEPKAYEGKSIAYEL
DNLIGDKIQRAIKQFADQWKADPDKLAFVATNYHSANSTKQVGMSTLKES
LDYQAYKEKQGDSAINKLKYKSQFERELVQFIREQIQPLKGH
>M6_Spy0664 ABC transporter ATP-binding protein
MSHEKKQLMQLSNIVKSYQNGDQVLKVLKGINLTVYEGEFLAIMGPSGSG
KSTLMNIIGLLDRPTSGDYTLHNTKIEILNDRELANVRNDEIGFVFQQFF
LLAKLTALQNVELPLIYAGVNVSKRREQAKQFLEKVGLGRRIKHLPSELS
GGQKQRVAIARALVNDPSIILADEPTGALDTKTGQQIMELLTELNKEGKT
IIMVTHEPEIADFATRKIIIRDGDITTDTTASVVID
>M6_Spy1582 Penicillin-binding protein
MVYEMTLAVIKCIENHLHKKVYKGASLALFQSGRWQEYHIGTIDGRRPVD
ANLVYDLASVSKVVGVATICNILLNNGTLALDDPLKVYYPSIADTTVTIR
QLLTHTSGLDPYIPNRDVLNAQQLRKALNHLTQKENKNFYYTDVNFLLLG
FMLEELFSESLDQIFDKTIFTPFGMYHTSFGPRPEAVPTLKGVSDGEVHD
PKAKILKKHSGSAGLFSTLADLESFSNHYLNDPFSDCLWRNYSQQTIERS
LGWNLDGDWISHTGYTGPFLMLNKKEQTAAIFLTNRTYDEDDKSKWLKER
QLLYNALKHDLTTPVS
>M6_Spy0955 ABC transporter permease protein
MIKKTLWKDILRAIKNSKGRFISLFFLMALGSFALVGLKVTGPDMERTAS
RYLERHQVMDLTVLASHQFSQADKQELDTLKGAHLEYGHLLDVSLTSNQK
SLRLYSVPKKVSKPVLVKGSWPKRETDLVLSSSLAKNYQIGDELAVTSPM
EGLLTTTHFQVVGFANSSEVWSKSNLGSSSTGDGSLYAYAFVNPNVFKSA
FNLLRIRFSNLRLTNAFSKDYQKRVTQNQAHLDNLLKDNGQKRYDDLQNQ
YDLALKNGRAALAKETVKLAASEENLTFLEVSALQEAKHQIEQGKQALAK
EEKQLEQVQATKDKLEKPSYLTYNRSTLPGGEGYHTYATSTTSISNVGNI
FPVVLYLVAALVAFTTMTRYVDEERTSSGLLKAIGYSNKDISLKFLIYGL
LASFLGTTLGIIGGTYLLSALISEILTGALTIGKTHLYSYWFYNGIAYLL
AMLSAVLPAYLIVKKELFLNAAQLLLPKPPSKGPKIWLEHLTFVWKALSF
THKVTIRNIFRYKQRMLMTIVGVAGSVALLFAGLGIQSSLAKVVEHQFGD
LTTYDILAVGSAKATATEQTDLASYLKQEPITGYQKVSYASLTLPVKGLP
DKQSISILSSSATSLSPYFNLLDSQEQKKVPIPTSGVLISEKLASYYKVK
PGDQLVLTDRKGQSYKVTIKQVIDMTVGHYLIMSNTYFKNHFKGLEAAPA
YLIKVKDKDSKHIKETASDLLTLKAIRAVSQNANHIKSVQLVVTSLNQVM
TLLVFLSILLAIVILYNLTTINIAERIRELSTIKVLGFYDQEVTLYIYRE
TISLSLVGILLGIYLGKGLHTYIMTMISTGDIQFGVKVDAYVYLVPILVI
LSLLAVLGIWVNRHLKKVDMLEALKSID
>M6_Spy0584 SagG
MSFVQLTNVVKSYKNGKKAVNDVSLSIEAGNIYGLLGPNGAGKSTLINLI
LGLIPLSSGKITVLGQSQKTIRKISSQIGYVPQDIAVYPDLTAYENVELF
GSLYGLKGAQLKKQVLKSLEFVGLHSQAKQFPSQFSGGMKRRLNIACALV
HSPKLIIFDEPTVGIDPQSRNHILESIRLLNKEGATVIYTTHYMEEVEAL
CDYIFIMDHGQVIEEGPKFELEKRYVANLANQIIVTLTDSRHLELADKPD
WSLIEDGEKLMLKIDNSDMTSVVHQLTQANITFSEIRHNHLNLEEIFLHL
TGKKLRD
>M6_Spy0866 Multidrug resistance ABC transporter ATP-binding and permease protein
MKRLRPCVKGYLKESILGPLFKLLEALFELLVPLLVANMIDLSISQHNSQ
GILRVVLTLFGLATIGLLLSVTAQYFSSKAAVGFTRQMTDDLFKKIMFLS
KEDQDHLGYASLLSRLTSDSFQIQTGINQFLRLFLRAPIIVCGAMVMAYW
ISPSLTLWFVMMVIVLLTLVFVMSHLLGPLYLLIRRETDHLVRLTSQQLQ
GIRVIKAFNQTQKELQAFKQQNMLLSRHQYQAATLANVLNPMTFLVVNLT
LLILIWQGSWQVAHRSLSQGMLVALINYLLQILAELLKMTMLMGTINQSV
TAAKRINQVFVLADEAPLPLLKDGPISTHLLTIRHLTFTYPGAAEPSLYD
IQLSADQGEWIGIIGGTGAGKTTLIDLICQTYSQYSGEVSLNWQGEVPKT
LTEWRNVIALVPQKAQLFKGTIRNNLLLGQSMPISDEELWRALELAQAKE
FVAALPEQLEAPVEAFGRHFSGGQRQRLAIVRALLKPKPILILDDASSAL
DNETRGRLFKALKEELSDVLVILVTQSIKNLQFADKILVLEQGHQLDFAS
HDQLKVSNALYQEMLALYVKGE
>M6_Spy1638 Lantibiotic transport ATP-binding protein
MMYNISLGRESVSGEQVIETCKRVSIYDDIRSMPMKFHTPLFRDNPSLSG
GQKQRISLARELVTTPRILVLDEPTSALDVKTERIIQKNVEALHCTRILV
THRLNTVEKADKILIMDNGKIIDYGNHHYLYKNNKDYCDLYDSYMNKYQE
EEVK
>M6_Spy0983 SpeK
MLNFKKNVSDYSKYYILSIVLLWIGMFFVPWDKTLFGVSIYLFVMQKLFI
VFGLTAIFMAFVSKKINLFIWGILFIFAFWINMFLLFSVLPILGN
>M6_Spy0867 Multidrug resistance ABC transporter ATP-binding and permease protein
MIKTDHHLLKRVLQDLLKKPLPVCILVIASFVQVGLSVYLPVLIGKAVDM
SLSVNSWQTLKWLLGQMLVVIVVNTLIQWVMPLVYSRLLYQYSQQLKDKL
LEKIHRLPFAYLDRQTIGDLVSRVITDTEQLINGLQMVFNQFILGLLTIL
CTIIAMAQIDWLMLILVLVLTPSSLFLARFIAQKSFHYAQAQTKSRGNLA
QFTEEILRQEGLVQLFNAQEQSICDYHVLNKTYCEASQKAIFYASTVNPA
TRFINSVIYALLAGLGAVRIMAGLFSVGQLTTFLNVVVQYTKPFNDISSV
LAEIQSSLACAQRLYDLLDIEIKEQEHFLTFKASAVKGQIDFEEVSFSYQ
KDRPLLKDINFSVPAGSKVAIVGPTGAGKSTLINLLMRFYELDAGSIKLD
KVPIKCYAKEELRSITGMVLQETWLKDATVHELIAYGSEEASRDEVVAAA
KAAHAHFFIMQLPKTYDTYLSASDDALSQGQLQLLAIARMFLKKPKVLIL
DEATSSIDIRTEAVIQEVLKELMRGRTSFIIAHRLSTIQSADLILVMDQG
RLVEWGTHASLMSKNGCYARLQKIE
>M6_Spy1636 ABC transporter permease protein
MIWSITKSNIKKNFSLYRIYFLATIGLLSIFIAFLNFISDKIITEKIGDS
GQALVIANGSLVFLTVFLVIFLIYFNNFFVKKRSQELGVLAILGFSKREL
TQLLTLENLVILVLSYLVSLLLGPTLYFLAVLVITHLLELTLEVQWFITA
NEIIESLGILVVVFLINVITNGLIISKQSLIEFVNFSRKAEKKIKIRKVR
AIIAITALLLSYILCLATVFSSTRNMLLSIGMVPVSLLIIVLVVLGTVFT
IRYGLAFVVSLLKGNKKRLYRPLSNIIYPKFNYRIATKNKLLTVLGGLLT
VTVSVAGMMVMLYAYSLNGIERLTPSAIEYNVKSENGQVNVTTILENDQV
SLVDVDLLRLNTNPEVTITESGQTIPYFDIINYSDYKELMKAQGRINSIE
GSKSLPLLINYYPTEISLGKTFNLGNAYDVTVKQVSTHNVFSFSTSVTTL
VVSDKLYAKLSSCFPEKEMTTRTFNGNSIRSSEAFYNQFSMVPDVISSYS
KEYTVKTANIATYIFITFLSILFIICTGSILYFTSLIEIMENKEEYGYLS
KLGYSKKMIHRILRYETGILFLIPVFIGIVNGGMLLIYYKYLFMDTLVAG
NIIMLSLLLCLLFFLIIYGTFYVLTLRSVTSITKN
>M6_Spy1637 ABC transporter ATP-binding protein
MKQLVLKDVCKKYPNQLNYALDHINLIVEKGEFVAVMGRSGSGKTTLLNV
TSIIDKIDSGSIYCADKEISAFSDNEATNFRKNDIGFVFQDYMLLDSLTI
RENISVALSLKNIDSSKIDDLINSYAKRFNLYEQLKKYPYQLSGGQRQRV
SIIRAIIKEPEIIFADEPTGALDLKSSEETMMILSEINKTEKVTILMVTH
DVLSASYADRVVLLKDGKLHLEIDKEDCGETFYDVISQALSDRGE
>M6_Spy1421 ABC transporter ATP-binding protein
MIEFKHVSKLYGDKEALSDLNVTINDGEIFGLIGHNGAGKTTTISILTSI
IEASYGEVFVDGQLLTENREAIKKQIAYVPDSPDIFLNLTPNEYWQFLAK
IYGVSDEDREERLAQLTTLFELKEEGNQTIDSFSHGMRQKVIVIGALVSN
PNIWILDEPLTGLDPQASFDLKEMMKAHAASGHTVLFSTHVLSVAEQLCD
RIGILKKGKLIFVGTIDELKEHHPDKDLESIYLELAGRKAQEEG
>M6_Spy1159 Type II restriction-modification system restriction subunit
MILVNLGGLIMLKDLGVIFDEQSRIASEFLSKNDTEVILSTEFKENYKKH
IDMLGDEIYFEQYNSKYHTNSKFIIIPNQWFYLAFIAAPYYKEFLKYKSI
LLDTLSGDDFKEFCQTARNGELDENLFDTISVDLTETDTLFLKKFVTDYH
WWHGGKEIHRGDSFISPILALLKLINASSEHVAIIVKYLVDADFDLSDVN
KYFELVEMDSRSVVTTNYDNTNLVGDNILLYGVPGSGKSFKIATEYCNDE
NRMERLVFHPDYMNTDFVGQIMPTVKENGDITYLFSPGPFTRIVKKAIDN
PSEHYYLVIEELNRGNAPGIFGEIFQLLDRSASGESVYGINNSILATEIY
GDKSHQIKIPSNLSLLATMNTADQNVFTLDTAFQRRWTMEMIENDVDLSE
YGNYFIADTQYSWKVFNKVINKKILETSSQTLTSEDKRMGAYFISGNVLN
IERIHQVPAGDSGNEFNKKNKRFAEKVLKYLWDDAFKFNREDIFDVALYP
SLEAIIKRFTDNDNPENGRFDVFAKDIKEELENLKEATLIDNNNDTGEED
VDSTE
>M6_Spy1631 Type I restriction-modification system methylation subunit
MAEKTTSLRQALWHSADQLRGQMDANDYKNYLLGLIFYKHLSDKLLLAVC
DNLDQHFNTFTDAQKIFEDAYQDEDLKDDLISVVTGDLGYFIEPTLTFEK
LIQDVYHNTFQLESLAQGFSDIEQSGEDFENLFEDIDLYSKKLGSTPQKQ
NQTISNVMKTLNEIDFEAVDGDTLGDAYEYLIGEFASESGKKAGEFYTPQ
AVSHLMTQIVFLGREDQKGMTLYDPAMGSGSLLLNAKKYSNQSDTVSYYG
QEINTSTYNLARMNMMLHGVAIENQHLGNADTLDADWPTDEPTNFDGVLM
NPPYSLKWSATAGFLTDPRFSSYGVLAPKSKADFAFLLHGFYHLKNTGTM
AIVLPHGVLFRGAAEGKIRQKLLEQGAIDTIIGLPSNIFYNTSIPTTIII
LKKNRTNKDVFFIDASKEFDKGKNQNTMTDSHIKKILDAYKSRDNSDKFS
YLASFDEIIENDYNLNIPRYVDTFEEVPVKPLPELAKQLSDIDQEIAKTN
AKLDQLMKQLVGTTKEAQDELDTFRN