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# Streptococcus pyogenes phage 6180.4

>M28_Spy1233 hyaluronoglucosaminidase
MTSVETIPIKIVFDRKDASEWQSTNPVIDEGELVVELDTHKLKVGDGKTS
YNDLPYYEGPQGESITKVQLSENGDLSVWIGDKETKLGNIKGQKGDKGTS
ITDITKDGETLTIKLSDDTQKIFNIPNGQKGDRGKGVESARIDESGHLKL
KIEEESELDLGNVKGESGPKGDSITITNHKRVSDGTQVSFSDGTQIVVPK
GDTGDVNGINLEDYVKKSELKNVGSADVKAINDFLGLSQKVFTSSYSYTD
SLLKSYAKPSYSASWYVNESTVSTKNGDKVLITIHNTTTQADNYLEVAVT
YVGANYVTATSTGRLLTTPGEVKVVTKKQAEKDYAAKKHKHEISDIAGLN
ERLSGYLRQADIQSQLNNIGKLKDTQTGQYLEVKVVDKGQVPSNTSGMIV
FERS
>M28_Spy1226 phage-associated cell wall hydrolase
MTFLDDIKQGCLDGWTKYKILPSLTAAQAILESGWGKHAPHNALFGIKAD
ASWTGKSFDTKTQEEYQPGIVTDIVDRFRAYDSWTDSIIDHGKFLNDNPR
YKAVIGETDYKKACYAIKAAGYATASSYVELLIQLIEENDLQSWDREALK
NNKEETMTTANEIVQYCVNLANSGMGVDKDGAHGTQCCDLPCFVAKNWFG
VDLWGNAIDLLDSASAQGWEVHRMPTEANPKAGATFVQSVPYHQFGHTGI
VIEDSDGYTMRTVEQNIDGNADALYVGAPARFNTRDFTGVVGWFYPPYQG
DTVTQPVSTEPQTSDTIVETAKTGTFTLDVAEINIRRWPSLASEVVGIYK
QGDTVSFDSEGYANGYYWISYVGGLGMRDYLAIGQTDKDGNRISIWGKLN
>M28_Spy0977 phage protein
MTSVETIPIKIVFDRKDASEWQSTNPVIDEGELVVELDTHKLKVGDGKTS
YNDLPYYEGPQGESITKVQLSENGDLSVWIGDKETKLGNIKGQKGDKGTS
ITDITKDGETLTIKLSDDTQKIFNIPNGQKGDRGKGVESARIDESGHLKL
KIEEESELDLGNVKGESGPKGDSITITNHKRVSDGTQVSFSDGTQIVVPK
GDTGDVNGINLEDYVKKSELKNVGSADVKAINDFLGLSQKVFTSSYSYTD
SLLKSYAKPSYSASWYVNESTVSTKNGDKVLITIHNTTTQADNYLEVAVT
YVGANYVTATSTGRLLTTPGEVKVVTKKQAEKDYAAKKHKHEISDIAGLN
ERLSGYLRQADIQSQLNNIGKLKDTQTGQYLEVKVVDKGQVPSNTSGMIV
FERS
>M28_Spy0338 hypothetical protein
MKWSDFMKTKSKRFLNLATLCLALLGTTLLMTRPVKAEVSEIGHDHVTIS
SNGQTDEGAAYGRGHDDGSKFGYEAGLQSSWNESEPPSSDKIPEPSVNPY
ESSNEQDREDYKEGFRDGYPGGYVAGWRKTHPIEATLQYLWYTVSSWFES
LFNNSK
>M28_Spy0108 signal peptidase I
MTNYLNRLNENPLFKAFIRLVLKISIIGFLGYILFQYVFGVMIVNTNQMS
PAVSAGDGVLYYRLTDRYHINDVVVYEVDNTLKVGRIAAQAGDEVNFTQE
GGLLINGHPPEKEVPYLTYPHSSGPNFPYKVPTGTYFILNDYREERLDSR
YYGALPINQIKGKISTLLRVRGI
>M28_Spy0088 hypothetical protein
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEK
LNLALMAVQTRTKEITLNGCHITILRTDRYISIHDDEGEVMKIE
>M28_Spy1199 prepilin peptidase family
MIAFFSICSGILLTHLFYCLLLYFPDNGQEQLSKQTVIVCDQLTFAKRVF
RQLQNHFITSQKIFFSLEISLIIILWASMVHWVSASYCYLLLFSLLFSLF
DWRSQEYPFILWLFSFVSLLLFYSINYLSLILLLLGLLAHLRPFSIGAGD
FFYLASLALVLDLTSLIWLIQLASLAGITACLLLGIKRIPFIPYLSFGLF
WIVLLEHF
>M28_Spy0087 ComG operon protein 4
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHF
EHLYRHQQKLAILQQKQRVLDISSTKIVTEGNSLTVPKSITVNHPYRLVI
DQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP
>M28_Spy1459 EcsB
MKALFLKRRQDFQKQQNKYLRYVLNDHFVLVLMFLLGYAMVQYGQLLNHF
PTNHLPIQVCLGILIPLLLSMGSIATYLEEADQHFLLPKEEEVISYIKQA
ERLSFLLWGTLQTAILLFLYPIFRRLGLSLFIFIILVLILLALKRVVLSR
KTRYFLRGNRLDWAKAVAFESNRKQSILKFYSLFTTVKGISTKVKERTYL
NPLLKLVKQTPSNLWLSLYARAFLRSSDYLGLFLRLMLLSSLSVFFIHNL
YLSVSLALIFNYLVVFQLLSLYYHYDYHYMTSLYPENSRSKKKNVLSFLR
GLSFLMLIVNMLCCSSAPKALILIVGMVFIACIYLPYKLKKIID
>M28_Spy0286 inner membrane protein
MKLTLNRILFSGLALSILFTLTGCVGRDAHGNPKGMIWEFLGKPMSYFID
YFANNAGLGYGLAIIIVTIIVRTLILPLGLYQSWKASYQSEKMAFLKPVF
EPINKRIKQASSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFF
SAMYFAAQYTKGVSTSTFMGIDLGSRSLVLTAIIAALYFFQSWLSMMAVS
EEQREQMKTMMYTMPIMMIFMSFSLPAGVGLYWLVGGFFSIIQQLITTYL
LKPRLHKQIKEEYAKNPPKAYQSTSSRKDVTPSQNMEQANLPKKIKSNRN
AGKQRKR
>M28_Spy0202 conserved hypothetical protein
MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVYLFARAI
QWLSFDGSIGVGIILFTLTIRLMLMPLFNMQIKSSQKMQDIQPELRELQK
KYAGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALT
RVSFLKTGTFLWVELAQHDHLYLLPVLAAVFTFLSTWLTNLAAKEKNVMM
TVMIYVMPLMIFFMGFNLASGVVLYWTVSNAFQVVQLLLLNNPFKIIAER
QRLANEEKERRLRERRARKKAMKRK
>M28_Spy0317 clpP, ATP-dependent Clp protease proteolytic subunit
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLD
AQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTV
IASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRL
EKILAQNAGKTIKQIHKDAERDYWMSAEETLTYGFIDEIMENNELK
>M28_Spy0084 comYA, ComG operon protein 1
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDR
MAPLISHFKFVAGMIVGEKRRCQVGSCDYKLSKDKQLSLRLSSVGDYRGQ
ESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMY
QLISSYHQEAQVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHR
PDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGVYVRLLELGVT
KAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGH
LNPKQAKLEKII
>M28_Spy0085 comYB, ComG operon protein 2
MTLLKTNLNIIPHRTGINKLISFLRQDISIPSKLSLKKLSSKHQHKFIQL
LANLLSTGFSFAEVIAFLKRSQLLQLDYVLKMEESLLKGQDLADMLSGLG
FSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRRKTVEVITYPLILL
LFLFVMMLGLRRYLVPQLETQNQITYFLNHFPAFFIGFCSGLILLFGMVW
LRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWGTLIGQGLDLMTI
LDIMAIEKSSLMKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYG
EIKSKLGAELEIYAQESWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAA
ILLPIYQNMGGIF
>M28_Spy0086 comYC, ComG operon protein 3
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETG
NAAVVKLVENQAELYELSQGSKPSLSQLKADGSITEKQEKAYQDYYDKHK
NEKARLSN
>M28_Spy0089 comYD, ComG operon protein 6
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQD
NWLLFSHQLREELSGARFYKVADNKLYVEKGKKVLAFGQFKSHDFRKSAS
NGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD
>M28_Spy0887 ffh, signal recognition particle, subunit FFH/SRP54
MTMAFESLTQRLQDVFKHIRGKKKLSESDVQEVTKEIRLALLEADVALPV
VKTFIKRVRERAIGHEIIDTLDPTQQILKIVNEELTSILGSETAEIDKSP
KIPTIIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQ
LKTLGQQINVPVFDMGTDHSAVDIVRKGLEQARENRNDYVLIDTAGRLQI
DEKLMEELRDVKALAQPNEILLVVDSMIGQEAANVAYEFNHQLSITGVVL
TKIDGDTRGGAALSVREITGKPIKFTGIGEKITDIETFHPDRMSSRILGM
GDLLTLIEKASQEYDEKKSLELAEKMRENTFDFNDFIEQLDQVQNMGPME
DLLKMIPGMAGNPALANIKVDENQIARKRAIVSSMTPAERENPDLLNPSR
RRRIAAGSGNSFVEVNKFIKDFNQAKSMMQGVMSGDMSKMMKDMGINPNN
LPKNMPAGMPDMSSLEGMMGQGGMPDLSGLGGDMDMSQVFGKGFKGKIGQ
FAMKQAMKRQANKLKKAKKKRK
>M28_Spy0453 ftsY, cell division protein
MGLFDRLFGKKETPKVAEEKLEENLLTETTQKEELSEKANEQNKIEVVQQ
EDVSSEGAGSVENGPEAASVNAQVEEETGDNSNHPSEDTNEFAADKTDLK
VSELSQSTASEPKDLVDQPVVEQFPTKQAQADASNDSANEEAVDTSKEQS
SSQQVMEDYYRRKAALEKSLQEKAAATVPVMPEEVPQENQASTSAEASQN
KATHDTIPETDQEKYKRSLKKTRTGFSARLNSFFANFRRVDEEFFEDLEE
MLILSDVGVHVATTLTEELRYEAKLENAKKPDALKRVIVEKLVDIYEKDG
RYNEAINYQDGLTVMLFVGVNGVGKTTSIGKLAYRYKQEGKKVMLVAADT
FRAGAVAQLVEWGRRVDVPVITGPEKADPASVVFDGMEKAVAKGVDILLI
DTAGRLQNKENLMAELEKMGRIIKRVLPDAPHETLLALDASTGQNALSQA
KEFSKITPLTGLILTKIDGTAKGGVVLAIRQELDIPVKFIGFGEKVDDIG
EFHSEDFMKGLLEGIL
>M28_Spy0617 lsp, lipoprotein signal peptidase
MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLTYLQNNG
AAFSILQDQQWFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGI
GNFIDRLRLAYVIDMVHLDFVDFAIFNVADSYLTVGVILLVICLWKEEDY
GN
>M28_Spy0644 mur1.1, autolysin
MKVKKRRRRAKSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYADHETLT
FVRKISHAAQSVAQKKQLYSSVMMAQAILESNNGKSQLSQKPYYNFFGIK
GSYKERSVIFPTLEDDGQGNLYQIDAAFRSYGSLTACFLDYARVLNDPLY
DKTHKKFWSHYQDATATLTGTYATDTTYNTKLNELIEWYQLTNFDGLMK
>M28_Spy0645 mur1.2, autolysin
MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSSTRHFID
EIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAY
NGSSVTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGA
RKSNTLSYQDATAALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQE
TGLATSGYVWNEYRRNYTDAETLAVDEAWAKRMTY
>M28_Spy1524 secA, protein translocase subunit
MANILRKVIENDKGELRKLEKIAKKVESYADQMVSLSDRDLQGKTLEFKE
RYQKGETLEQLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEM
RTGEGKTLTATMPVYLNAIAGEGVHVITVNEYLSTRDATEMGEVYSWLGL
SVGINLAAKSPAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRP
LNFALVDEVDSVLIDEARTPLIVSGAVSSETNQLYIRADMFVKTLTSVDY
VIDVPTKTIGLSDSGIDKAESYFNLSNLYDIENVALTHFIDNALRANYIM
LLDIDYVVSEDGEILIVDQFTGRTMEGRRFSDGLHQAIEAKEGVRIQEES
KTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIPIPTNRPIA
RIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKL
VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGV
RELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRF
GSDRIKAFLDRMKLDEEDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQ
YDDVMREQREIIYANRRDVITANRDLGPEIKAMIKRTIDRAVDAHARSNR
KDAIDAIVTFARTSLVPEESISAKELRGLKDDQIKEKLYQRALAIYDQQL
SKLRDQEAIIEFQKVLILMIVDNKWTEHIDALDQLRNAVGLRGYAQNNPV
VEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQRATTAAPQN
IQSQQSANTDDLPKVERNEACPCGSGKKFKNCHGRKSFS
>M28_Spy0401 secG, protein translocase subunit
MYNLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFERTKARGF
EAFMQRFTAVLVFFWLAIALVLAILSSK
>M28_Spy0063 secY, protein translocase subunit
MLKVVQSKSSNEGILIMFLKILKDALKIKTVRNKIFFTIFIILVFRIGTH
ITVPGVNAKSLEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIV
VQLLQMDILPKFVEWGKQGEVGRRKLNQATRYISLVLAFAQSIGITAGFN
TLSNVALVKTPDIKTYLLIGALLTTGSVIVTWLGEQITDKGFGNGVSMII
FAGIISSIPSAIATIREDYFVNVKASDLHSSYLIVGILIIAVLAIVFFTT
YVQQAEYKIPIQYTKLMQGAPTSSYLPLKVNPAGVIPVIFASSITTIPST
IIPFVQNGRDLPWLNRLQEIFNYQTPVGMIVYALLIILFSFFYTFVQVNP
EKTAENLQKNSSYIPSVRPGRETEQFMSALLKKLATVGAIFLAFISLAPI
AAQQALNLSSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNTAE
>M28_Spy0959 sipC, signal peptidase I
MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKSGDLVTI
KKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQA
YLEKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKN
TNDSRRFGLINASQIKGLVTFRVLPLSDFGFVEVE
>M28_Spy0858 smf, hypothetical protein
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHF
IEAYKQLDIQKLKIEFKQFPSISILDKHYPMALKEIYNPPVLLFFQGNLD
LLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHL
ACLKNGGQTIAIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALS
YHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGRDIFAVPGNIL
DGKSEGCLQLIKEGATCVTSGMDILSEY
>M28_Spy1553 spi, signal peptidase I
MLNFTSPTLTKRKRFSLNKRNHMKQFIKEWGPFTLFLILFGLSRLFLWQA
VKVDGHSMDPTLAHGERLIVFNQARIDRFDIVVAQEEENGQKKEIVKRVI
GLPGDTISYNDDTLYINGKKTVEPYLAEYLKQFKNDKLQKTYAYNTLFQQ
LAETSDAFTTNSEGQTRFEMSVPKGEYLLLGDDRIVSRDSREVGSFKKEN
LIGEVKARFWPLNKMTVFN
>M28_Spy1665 yajC, protein translocase subunit
MGFPTILMFVVMLGLIWFMQRQQKKQAQERQNQLNAIEKGDEVVTIGGMF
AIVDEVDTTAKKIVLDVDGVFLTFELSAIKRIVTKATTETTLVETEETSV
VNEPAVETVDSTDTDSAIESH