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# Streptococcus pyogenes MGAS10394, MGAS10394

>M6_Spy0683 Autolysin
MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSSTRHFID
EIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAY
NGSSVTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGA
RKSNTLSYQDATAALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQE
TGLATSGYVWNEYRRNYTDAETLAVDEAWAKRMTY
>M6_Spy1342 N-acetylmuramoyl-L-alanine amidase
MAFLDKIKSAVIAEWHTHKILPSLTAAQAILESGWGKYAPHNALFGIKAD
SSWTGKSFNTKTQEEYQPGIVTDIVDRFRAYDSWEDSIADHGQFLADNPR
YKAVIGEADYKKACHAIKDAGYATASGYADLLIQLIEENNLQEWDAEAIK
NKEEQMISSQCREVIEFFINLANAGVGVDKDSFAGWQCADVPCYAAKHWF
GVDLWGNAIDLLDSAAAVGWEVHRMPTDANPRTGAFFVQSVPCHQFGHTG
IVIEDSDGYTMRTVEQNIDGNPDALYVGAPARFNTRDFTGVLGWFYPPYQ
GDIVTQPVSTEPQNSDTIVETPKTGTFTLDVAEINIRRWPSLASEVVGSY
KQGDTVSFDSEGYANGYYWISYVGGLGMRNYLAIGQTDKDGNRISIWGKL
N
>M6_Spy0113 Protein translocase subunit secY
MLKVVQSKSSNEGILIMFLKILKDALKIKTVRNKIFFTIFIILVFRIGTH
ITVPGVNAKSLEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIV
VQLLQMDILPKFVEWGKQGEVGRRKLNQATRYISLVLAFAQSIGITAGFN
TLSNVALVKTPDIKTYLLIGALLTTGSVIVTWLGEQITDKGFGNGVSMII
FAGIISSIPSAIATIREDYFVNVKASDLHSSYLIVGILIIAVLAIVFFTT
YVQQAEYKIPIQYTKLMQGAPTSSYLPLKVNPAGVIPVIFASSITTIPST
IIPFVQNGRDLPWLNRLQEIFNYQTPVGMIVYALLIILFSFFYTFVQVNP
EKTAENLQKNSSYIPSVRPGRETEQFMSALLKKLATVGAIFLAFISLAPI
AAQQALNLSSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNTAE
>M6_Spy0682 Autolysin
MKVKKRRRRAKSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYADHETLT
FVRKISHAAQSVAQKKQLYSSVMMAQAILESNNGKSQLSQKPYYNFFGIK
GSYKERSVIFPTLEDDGQGNLYQIDAAFRSYGSLTACFLDYARVLNDPLY
DKTHKKFWSHYQDATATLTGTYATDTTYHTKLNELIEWYQLTNFDGLMK
>M6_Spy1139 ATP-dependent Clp protease proteolytic subunit
MHKFWNWAKNEGERTLFLNGVIASESWFGDEVTPQLFKDELLSEQGDITL
WINSPGGDVFAAAQIYNMLMDYKGAVTVNIDGIAASAASVIAMAGTIVNM
SPVSMMMIHNPATFASGDKREMEKAIQLLNEVKESIINAYEIKTSLSRQK
LSNLMDGETWLNAKKAVELGFADQIIFDGTHDNDESQDAYAFSMQTVTNQ
VVAKCEQLIDKPKVAVSTLEKRLQLLKP
>M6_Spy0136 ComG operon protein 3
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETG
NAAVVKLVENQAELYELSQGSKPSLSQLKADGSITEKQEKAYQDYYDKHK
NEKARLSN
>M6_Spy0065 Phage-associated cell wall hydrolase
MTFLDKIKQGCLDGWTKYKILPSLTAAQAILESGWGKHAPHNALFGIKAD
ASWTGKSFDTKTQEEYQPGIVTDIVDRFRAYDSWTDSIIDHGKFLNDNPR
YKAVIGETDYKKACYAIKAAGYATASSYVELLIQLIEENDLQSWDREALK
NNKEETMTTANEIVQYCVNLANSGMGVDKDGAHGTQCCDLPCFVAKNWFG
VDLWGNAIDLLDSASAQGWEVHRMPTEANPKAGATFVQSVPYHQFGHTGI
VIEDSDGYTMRTVEQNIDGNADALYVGAPARFNTRDFTGVVGWFYPPYQG
DTVTQPVSTEPQTSDTIVETAKTGTFTLDVAEINIRRWPSLASEVVGIYK
QGDTVSFDSEGYANGYYWISYVGGLGMRDYLAIGQTDKDGNRISIWGKLN
>M6_Spy0135 ComG operon protein 2
MISFLRQDISIPSKLSLKKLSSKHQHKFIQLLANLLSTGFSFAEVIAFLK
RSQLLQLDYVLKMEESLLKGQGLADMLSGLGFSDAILTQISLADRHGNIE
TTLVAIQHYLNQMARIRRKTVEVITYPLILLLFLFVMMLGLRRYLVPQLE
TQNQITYFLNHFPAFFIGFCSGLILLFGMVWLRWRSQSRLKLYSRLSRYP
FLGRLLKQYLTSYYAREWGTLIGQGLDLMTILDIMAIEKSSLMKELAEDI
RMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELEIYAQESWE
QFFSQLYQVTQLIQPAIFLVVAVTIVMIYAAILLPIYQNMGGIF
>M6_Spy1685 Protein translocase subunit
MGFPTILMFVVMLGLIWFMQRQQKKQAQERQNQLNAIEKGDEVVTIGGMF
AIVDEVDTTAKKIVLDVDGVFLTFELSAIKRIVTKATTETTLVETKETIV
VNEPAVETVDSTDTDSAIESH
>M6_Spy0904 signal recognition particle subunit FFH
MTMAFESLTQRLQDVFKHIRGKKKLSESDVQEVTKEIRLALLEADVALPV
VKTFIKRVRERAIGHEIIDTLDPTKQILKIVNEELTSILGSETAEIDKSP
KIPTIIMMVGLQGAGKTTFAGKLANKLIKEEDARPLMIAADIYRPAAIDQ
LKTLGQQINVPVFDMGTDHSAVDIVRKGLEQARENHNDYVLIDTAGRLQI
DEKLMEELRDVKALAQPNEILLVVDSMIGQEAANVAYEFNHQLSITGVVL
TKIDGDTRGGAALSVREITGKPIKFTGTGERITDIETFHPDRMSSRILGM
GDLLTLIEKASQEYDEKKSLELAEKMRENTFDFNDFIEQLDQVQNMGPME
DLLKMIPGMAGNPALANIKVDENQIARKRAIVSSMTPAERENPDLLNPSR
RRRIAAGSGNSFVEVNKFIKDFNQAKSMMQGVMSGDMSKMMKDMGINPNN
LPKNMPAGMPDMSSLEGMMGQGGMPDLSSLGGDMDMSQLFGGGFKGKIGQ
FAMKQAMKRQANKLKKAKKKRK
>M6_Spy1007 ATP-dependent Clp protease proteolytic subunit
MPKRINLKGPLIANNSQEVYDYYGMEAASAKSIIEKLPEDNSDIILEVNS
NGGLVTVGSEIYTALRNYKGKVTAEITGMAASAASVAVMGVDKVVMSPTA
QMMVHKASFNWVAGNSDDLDKASNALKSSDKAIVNAYVAKTGLPEDEIME
LMKNETFMSAQDAVEKGFADEVMSFEAVASIDNQMLPQAVIDDYYANRSK
RKQEISNMLLEIEKEEILQGL
>M6_Spy0323 60 kDa inner membrane protein
MKLTLNRILFSGLALSILFTLTGCVGRDAHGNPKGMIWEFLGKPMSYFID
YFANNAGLGYGLAIIIVTIIVRTLILPLGLYQSWKASYQSEKMTFLKPVF
EPINKRIKQASSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFF
SAMYFAAQYTKGVSTSTFMGIDLGSRSLVLTAIIAALYFFQSWLSMMAVS
EEQREQMKTMMYTMPIMMIFMSFSLPAGVGLYWLVGGFFSIIQQLITTYL
LKPRLHKQIKEEYAKTPPKAYQSTSSRKDVTPSQNMEQANLPKKIKSNRN
AGKQRKR
>M6_Spy0354 ATP-dependent Clp protease proteolytic subunit
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLD
AQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTV
IASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRL
EKILAQNAGKTIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK
>M6_Spy0736 Hypothetical protein
MKELQLTNIEAQQLITLLKVIATQHNKTLTNNTSGHIDIVGQNHKRFILN
YFYSTNSKVFHLRETEHNYTLIRINLNNKFHKNSNGEKIWGNRINIFSEE
EYYLKADESTHYKAYPLPYETIKDTNDFLEMMSNLFDYTNINNPQDANIN
IQEDLI
>M6_Spy1495 N-acetylmuramoyl-L-alanine amidase
MRKRLKFPYFLTLLACFLLLIVCPLMSSQRIASADKEVRVNYSQKQFITK
MGKEVKPLAKYYGIRPSILIAQILLETHDGKTLLASKYHNLFSKKATPGQ
AAITLKSPKQTNQNVRYAIYKDDASAIRDYLRMLRQGKEVDKRLYRNLAT
EKGYKAPAKSLQKYLHYTDKTYARRLIQVIESNDLTNYD
>M6_Spy1550 Hyaluronoglucosaminidase
MSENIPLRVQFKRMTASEWARSDVILLESEIGFETDTGFVRAGDGHNRFS
ELGYISPLDYNLLTNKPNIDELATKVETAQKLQQKADKETVYTKAESKQE
LDKKLNLKGGVMTGQLKFKPAATVAYSSSTGGAVNIDLSSSRGAGVVVYS
NNDTSDGPLMSLRTGKETFNQSALFVDYKGTTNAVNIAMRQPTTPNFSSA
LNITSGNENGSAMQIRGVEKALGTLKITHENPSIKADYDKNAAALSIDIV
KKQESGGKGTAAQGIYINSTSGTTGKLLRIRNLNDDKFYVKPDGGFYAKE
TSQIDGNLKLKDPIANDHAATKAYVDGEVEKLKALLTAKQM
>M6_Spy0496 Cell division protein ftsY
MGLFDRLFGKKETPKVAEEKLEENLLTETTQKEELSEKANEQDKIEAVQQ
EDVSSEGAGSVENGPEAASVNALVEEETGDNSNHPSEDTNEFAADKTDLK
VSELSQSTASEPKDLVDQPVVEQFPTKQAQADASNDSANEEAVDTSKEQS
SSQQVMEDYYRRKAALEKSLQEKAAATVPVMPEEVPQENQASTSAEASQN
KATHDTIPETDQEKYKRSLKKTRTGFSARLNSFFANFRRVDEEFFEDLEE
MLILSDVGVHVATTLTEELRYEAKLENAKKPDALKRVIVEKLVDIYEKDG
RYNEAINYQDGLTVMLFVGVNGVGKTTSIGKLAYRYKQEGKKVMLVAADT
FRAGAVAQLVEWGRRVDVPVITGPEKADPASVVFDGMEKAVAKGVDILLI
DTAGRLQNKENLMAELEKMGRIIKRVLPDAPHETLLALDASTGQNALSQA
KEFSKITPLTGLILTKIDGTAKGGVVLAIRQELDIPVKFIGFGEKVDDIG
EFHSEDFMKGLLEGIL
>M6_Spy0988 Phage-associated cell wall hydrolase
MAFLDNIKQGCLDGWVKYKILPSLTAAQAILESGWGKHAPHNALFGIKAD
SSWTGKSFDTKTQEEYQPGVVTDIVDRFRAYGSWDESILDHGKFLNDNPR
YKAVVGETDYKKACHAIKEAGYATASGYAELLIQIIKENGLQFWDAEVLK
SNKEETMTTANEIVKYCVDLANSGMGVDKDGAYGT
>M6_Spy1464 EcsB
MKALFLKRRQDFQKQQNKYLRYVLNDHFVLVLMFLLGFAMVQYGQLLNHF
PTNHLPIQVCLGILIPLLLSMGSIATYLEEADQHFLLPKEEEVISYIKQA
ERLSFLLWGTLQTAVLLFLYPIFRRLGLSLLIFIILVLILLALKRVVLSR
KTRYFLRGNRLDWAKAVAFESNRKQSILKFYSLFTTVKGISTKVKERTYL
NPLLKLVKQTPSNLWLSLYARAFLRSSDYLGLFLRLMLLSSLSVFFIHNL
YLSVSLALIFNYLVVFQLLSLYYHYDYHYMTSLYPENSRSKKKNVLSFLR
GLSFLMLIVNMLCCSSAPKALILIVGMVFIACIYLPYKLKKIID
>M6_Spy0137 ComG operon protein 4
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHF
EHLYRHQQKLAILQQKQRVLDISSTKIVTEGNNLTVPKSITVNHPYRLVI
DQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP
>M6_Spy1281 Prepilin peptidase family
MIAFFSICSGILLTHLFYCLLLYFPDNGQEQLSKQTIIVCDQLTFAKRVF
RQFQNHFITSQKIFFSLEISLIIILWASMVHWVSASYCYLLLFSLLFSLF
DWRSQEYPFILWLFSFVSLLLFYSINYLSLILLLLGLLAHLRPFSIGAGD
FFYLASLALVLDLTSLIWLIQLASLAGITACLLLGIKRIPFIPYLSFGLF
WIVLLEHF
>M6_Spy0655 Lipoprotein signal peptidase
MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLTYLQNNG
AAFSILQDQQWFFVAITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGI
GNFIDRLRLAYVIDMVHLDFVDFAIFNVADSYLTVGVILLVICLWKEEDY
GD
>M6_Spy0139 ComG operon protein 6
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQD
NWLLFSHQLREELSGARFYKVADNKLYVEKGKKVLAFGQFKSHDFRKSAS
NGKGYQPMLFGISRSHIHIGQSQICITLKWKSGLERTFYYAFQD
>M6_Spy1526 SecA
MANILRKVIENDKGELRKLEKIAKKVESYADQMASLSDRDLQGKTLEFKE
RYQKGETLEQLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEM
RTGEGKTLTATMPVYLNAIAGEGVHVITVNEYLSTRDATEMGEVYSWLGL
SVGINLAAKSPAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRP
LNFALVDEVDSVLIDEARTPLIVSGAVSSETNQLYIRADMFVKTLTSVDY
VIDVPTKTIGLSDSGIDKAESYFNLSNLYDIENVALTHFIDNALRANYIM
LLDIDYVVSEDGEILIVDQFTGRTMEGRRFSDGLHQAIEAKEGVRIQEES
KTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIPIPTNRPIA
RIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKL
VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGV
RELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRF
GSDRIKAFLDRMKLDEEDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQ
YDDVMREQREIIYANRRDVITANRDLGPEIKAMIKRTIDRAVDAHARSNR
KDAIDAIVTFARTSLVPEESISAKELRGLKDDQIKEKLYQRALAIYDQQL
SKLRDQEAIIEFQKVLILMIVDNKWTEHIDALDQLRNAVGLRGYAQNNPV
VEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQRATTAAPQN
IQSQQSANTDDLPKVERNEACPCGSGKKFKNCHGRKSFS
>M6_Spy0974 Signal peptidase I
MVKRDFIRNIILALLAIVIFILLGIFVFSTFEIHKEAENAYLKNGDLVTI
RRNIKPKYKDFVVYRVDDKDYVSRVIASAGQSATSMDDILYINNQVVDEP
YIEKTKNDFLTTSPMGSLFTEDFNITTISKGNNKVIPSGKYLLLNDNRQN
KNDSREFGLIDKSQIKGVITFKILPLDQFGFIENE
>M6_Spy1577 Signal peptidase I
MLNFTSPTLTKRKRFSLNKRNHMKQFIKEWGPFTLFLILFGLSRLFLWQA
VKVDGHSMDPTLAHGERLIVFNQARIDRFDIVVAQEEENGQKKEIVKRVI
GLPGDTISYNDDTLYINGKKTVEPYLAEYLKQFKNDKLQKTYAYNTLFQQ
LAETSDAFTTNSEGQTRFEMSVPKGEYLLLGDDRIVSRDSREVGSFKKEN
LIGEVKARFWPLNKMTVFN
>M6_Spy0134 ComG operon protein 1
MVQVLAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDR
MAPLISHFKFVAGMIVGEKRRCQVGSCDYKLSKDKQLSLRLSSVGDYRGQ
ESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMY
QLISNYHQEAQVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHR
PDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGVYARLLELGVT
KAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGH
LNPKQAKLEKII
>M6_Spy0239 60 kDa inner membrane protein YIDC
MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVYLFARAI
QWLSFDGSIGVGIILFTLTIRLMLMPLFNMQIKSSQKMQDIQPELRELQK
KYAGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALT
RVSFLKTGTFLWVELAQHDHLYLLPVLAAVFTFLSTWLTNLATKEKNVMM
TVMIYVMPLMIFFMGFNLASGVVLYWTVSNAFQVVQLLLLNNPFKIIAER
QRLANEEKERRLRERRARKKAMKRK
>M6_Spy0440 Protein translocase subunit secG
MYNLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFERTKARGF
EAFMQRFTAVLVFFWLAIALVLAILSSK
>M6_Spy0880 Smf protein
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHF
IEAYKQLDIQKLKMEFKQFPSISILDKHYPMALKEIYNPPVLLFFQGNLD
LLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHL
ACLKNGGQTIAIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALS
YHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGRDIFAVPGNIL
DGKSEGCLQLIKEGATCVTSGMYILSEY
>M6_Spy0138 ComG operon protein 5
MIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMT
LNGCHITILRTDTYISIHDDEGEVMKIE