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# Anabaena variabilis ATCC 29413, ATCC 29413

>Ava_4106 Serine/Threonine protein kinase
MNNVLEMITEIEPGTLIYGRYQIQKLLGKGGFGRTYLALDNQRFDEPCVL
KEFVPTASQEKNVCKSKELFEREAKVLYKLKHPQVPQFLAWFTDSDRTFI
VQEYIDGRTYSEILFERVSETGQPFSEIEVRTWLTDVLPVLDYLHDRKII
HRDISLENIMLPHHQSKPVLIDFGAVKENVTQLMSPDSINFYNSIHTSVV
GKYGYSPPEQLRLGISYPSSDIYALGVCAVVLLTGKMPHLLLDESLNWQW
RSQVNIADDLAAIIDRMLIESPTARFQSAKEIILKLNKLHNNSPTVTQVE
FKITSPIEAIKTRQQEKETNKALEELLILQNLERTLRQYHDKLPKPIYLN
LDLPEYMEKHTTPASESSGCAFKKTSKIAAKIINIFTRRVNRHIVRKSEA
TNVNYIQINTHDFLEKTSINRNSQILEVIKKEFTNFIGPIANLIMNKVLV
TFPDCSANQLIEILAASIPDKITAERFQNDTRKLIISNLYIVKTNE
>Ava_2198 SOS-response transcriptional repressor, LexA
MESLTQAQQELYEWLAEYIRIHQHSPSIRQMMQAMNLKSPAPIQSRLEHL
RTKGYIEWTEGKARTIRILQPIKQGVPVLGAIAAGGLIEPFTDAVEHIDF
SNFALPAQTYALRVTGDSMIEDLITDGDLVFLRPVPEPDQLKNGTIVAAR
VDGYGNTLKRFYRSGDRITLKPANPKYNPIEVAAIQVEVQGSLVGVWRGY
M
>Ava_4652 UspA
MLKKILVALDRSDIGQQVFEQALVLAKATQAKLLLLHVLSPEEEGSPHIP
MVSGYDYYPGLNGQSFELYQKQWDTFKNEGVRMLQTLCAKANTQGVSTEF
SQTLGNPGRTICKLATNWNADLIVMGHRGLSGVKELFLGSVSNYVLHHTP
CSVHIVHDLGRVKDTEPVQDPTQEPQPLPA
>Ava_0505 CheA Signal Transduction Histidine Kinases (STHK)
MLPEQQQRILGYFIEEARDHLNTIEQGLLNLESTLNDPEMINEVFRAAHS
IKGGAAMLGLTSIQHTSHRLEDCFKILKDNPVQVDQKLESLFLGVSDTLK
ALLEQLSGPFGLSEEVANTLMSETEPVFQWLHEHLEQLVQKGGTAEIGDH
AVSKPNTADSVGTLTEIFFRQDVATPAEATPKTSPVLPTYSPIVATDSDQ
WSEFQAQVLQTLREMLQLFKQPATPASRQNLQDCCNQLVKLGKTWNLPNW
CNLCKAAANAIANQENTYLTLAKIVITEIKQAQELVLRSRESEITISHRL
EALWGFPEMPLLEVAQNLLGDVPTAVSQSFITPITPTSEPTITNNEISAP
LIESPTDSVTSFTEISDQLSPQSAIAESIANTDIAFDHEDQTTYTTNKIH
THGPEVGLAELNTLADLFEGETPELDETWQQEEIIDINNASNLGVDVSES
TDEAIDSDLADFLSLEEDKEESEKTINNTEDLSLLFGENFLEKNNLESLD
LFKAPVTAGEIIQEARDNANQLPDSDDVIDDLLALKIDDEIQNSNELEQT
NTSSDFDDLFSDTETNLPTNSELQLIALPEDLSLNNIFNDSEENKQLLTE
KSEISDLLDLPPVDNLGNLWNSATEVEPEQILESVIEEDIAQALEESLFE
AAASGDIFVENRQFTSHLNESLDPDDLNITFLQDEQQLDLLFASDTSDDL
FGELTINTHDTHRIDVISDDIQFLREISQVSPPEIHDFSQQPEVLDFTPE
FTTQIQELSAIDDLSSLTSDLTDITFTETNDSSSLETVAETSELSLDDDL
SALNSDLTDITFTETNDSSSLETVAETNELDLDDDLSALNSDLTDITFAE
THDSSSLETVAETNELDLDDDLSALNSDLADITFAETHDSSSLETVAGTN
ELDLDDDLSALTSDLADITFTETNDSSSLETVAETSELSLDDDLSALTSD
LADITFTETNDSSSLETVAETSELSLDDDLSALTSDLADITFTETNDSSS
LETVAETSELSLDDDLSALTSDLADITFTETNDSSSLETVAETSELSLDD
DLSALTSDLTDITFTETNDSSSLETVAETNELDLDDDLSALNSDLADITF
AETHDSSSLETVAGTNELDLDDDLSALTSDLADITFTETNDSSSLETVAE
TSELSLDDDLSALTSDLADITFTETNDSSSLETVAETSELSLDDDLSALT
SDLADITFTETNDSSSLETVAETSELSLDDDLSALTSDLADITFTETNDS
SSLETVAETSELSLDDDLSALTSDLTDITFTETNDSSSLETVSETSELSL
DDDLSALTSDLTDITFTETNDSSSLETVSETSELSLDDDLSALTSDLTDI
TFAETHDSSSLETVAETSELSLDDDLSALNSDLTDITFAETNDSSSLETV
AETSELSLDDDLSALTSDLADITFTETNDSSSLETVAETSQLSLDDDLSA
LNSDLTDITFAETNDSSSLETVVETNELDLADDLSALTLDELITENHNFI
SIAVDDNTLSTSEFSELGLSLTNDENPEDIADSSGLLIDINPATEDVAGV
EVENVVSTSIDIPESVKSDTYIQDDFADLEALLEIEEPTFSADNDSIAGD
DFAALEALLGEDNPETALDEPPALAKIIKTTPTVSVTPAPLADEFSDLEK
LLAEADQTISHSSPVKPTVGKTPRTSNRRTARFEETMKVPVKQLDEMSNL
VGELVVNRNTLEQDHERLRQSLDNLLVQVQQLSDVGARMQELYERSLLEA
SLLASRKTREPVYEVPDANSDRGFSELEMDRFTPFHTLSQEMIELIVRVR
ESASDIDFVTEETERVARQFRQVTTQLQEGLTRARMVPFSQTIDRLRRGV
RDNAIKFGKQVELVIEGGDTLIDKMILDHLNDPLTHMLNNAIAHGIETPE
IREASGKPPVGTITIRAFHQGNQTVISVGDDGAGIDPERIKAKAVKLGIM
TPEQARTISRLEIYDLLFQSGFSTKDEADEIAGRGVGMDVVRSEISEIRG
AVNTDSTVGKGTTFTIRLPLTLSICKALCCVSDKARIAFSMDGVEDTLDI
PSKNVQHNADGQSFISWRDTVLPFRPLKELLTFNRQLGRGNVYGGTRDDD
MISVVVVRSGNTLIALQIDQVLSEQEIVIKQFEGPAPKPIGVAGATVLGD
GRIMPIADVLEIIDIFQGRMSKHAGGAPWQQTPPIAIEIPSVKIDPTVLI
VDDSITVRELLSLTFNKAGYRVEQARDGQEAWDKLRSGLPCDIVFCDIEM
PRCDGLELLSRIQKDSTLNHLPIAMLTSRGADKHRQMAIQLGASGYFTKP
YLEEALLEAAVRMLKGEKLVSQINA
>Ava_4486 UspA
MVNISSEPRRKIKHQATLKQELTMIEKILLAVSGLGHAEEMLKTLKEVPS
IQSAKVTVLHVVPSQATSSAMTDKWEEGGKILANAIQSLNLDPSQVSSIL
RQGDPKDVVCQVADEIDADLIIMGSRGLKRLQSILSNSVSQYVFQLSSRP
MLLVKDDIYVKKIKRVMVAIDNSDAAKHCLNLALFLLQGIVGSQLILANV
TTDLRGKTSDVSEINPDKNPVLASAVAEAQKYGVQTRCFTSSGKPGEEIC
RLADELNVDLLLLGSPDRRPSVAKNFVDLDRLIGASLSDYVRVNASCPVL
LARTTG
>Ava_A0032 Serine/Threonine protein kinase with TPR repeats
MSIQCPTCLTDNTDDAINCIACGTPLVYTSNSSASSALDLAAGTLLGQGR
YQIEKVLGRGGFGITYQGIFLQNSAYIAIKELWPEGAARQKNTVLWPSSL
PPIQKQQQLKKFQLEASYLHQCIHPNIVRIYEWFEENNTAYLVMELLSGR
SLQDILEKEGPLPEDKVKYYLLQIAESLKVIHANRLLHRDIKPDNIIVDS
QDRAVLIDFGAAREFMAGQTGDMTRILTPGYAPYEQYIQSGKRYPATDFY
ALCASMYELLTGQLPAEATERANTLLQGSTSTPLIPPRQLRPNLSPLIEK
VILTGMQFRVEDRFQTADELIDALNGKFISPSHKRAQELVKQGKLAEAVL
AYEKYLNSEPNNGEAAVELAIIQLHLDETQAEIAAKKAMQLKPNDGRSYG
VLGLVNCRKSNWSEALKNLEQAANLAPQEVWIQANLAWALGKSGNWQQAE
NTVNKALQLDANCTFALGLQAWIAVNQEQWKSGIRTASQAIFKSKQSSYT
NSQELQRWVYPYLIFALDKAVVTKQASDVERRIQEFITQVPDNSFGWGFK
GWKAAVKCLWTDAISDFEQASRKSKVSSWILINQGIAQEYLHNFQAAIQA
YETHTQQFSPHAFVLFRLGTLYGRLGQWEKARSYLEKAVHEKSNYAEAYH
NLGWVLLNIKDQDGQVENFREILSSYRKAVELYTEQQKHPLAQGIKQVFQ
AVGVNNF
>Ava_3159 Periplasmic Sensor Signal Transduction Histidine Kinase
MFQATRRRLAIWYTAVTAVLLLLFASGVYLYVRSTLVERIDDTLSHVVEI
VERSLVIEPVNGEPEKLRINVEASFRNNANTVEDDHIDLEWFSPTGDLIW
STFSEPLNIPIHSNRTGETVHVFKQDRWTNSKTQNSALTNQDSGLLLRQV
TQRVEFGRQVLGYLRVSHPWFEVTKPSRQLIFDLALGTGLMVISVAASGW
FLSGKAMEPVGESYQRLKQFTADASHELRSPITLIQTNVQVALADLELTE
TEAATSSNYRQQLKVVERLTQRLGKLVNDLLFLARQDSGVSRDGFSSCPL
DALLMDVVEEQQLVATEKAITLNLHLIDPADSETSPELLEHWFTLVGNWD
QLVRLFTNLIGNALHYTPPGGAVNVELVRVDRVRYNTSQLQIKVSDTGIG
IPAEALPRLFDRFYRVDPARTHKSGNVGKDNATGSGLGLAIAQAIVEHHH
GNIQVESTVGNGTTFIVTLPITLES
>Ava_3541 Multi-sensor Signal Transduction Histidine Kinase
MTTFLIKLQRLWRKTLSALTLDEITTVYQNRSQQQEWLVNRQRFLWQRLH
LWLWLVLGCLLTFTLRNVYDLFFPLRELKALPQVLRTQGLMINAAMLLSL
LICFTLHKTRFGHRHPGVLFLGSSWSLSLASQLFATLKGFALPDTLGWSL
LFLSQATLMPVRWTLHLVCQVGILVYYFGVNTALRLSTPAPYHPEIYNVT
FILYIFWFCIICDLGVYLYDRLQRSEFYARKELESANNKLRLAEAKYRSI
FENAIEGIFQSSPDGRYITANPALARIYGYTSPEEVTENFTDIEHQLYVD
PKRRAEFVRLMEESGLAPEFESQIYRQDGSVVWISEKAYAVRDEQGNLLY
YEGLVEDITQRKQAQESLRVFFHAVSHDLRNPVLGTLMVLRNLLNDEAGE
QGAGSRGQGAGEAGEAGGELTARFSPSPQSPVPNPQSPIPSPQSPVPSPQ
FPVPNTQSPIPLPRSILERMVQSSDRQLNLINSLLEAHIGEVQGLSLQCQ
PVQLQMVVEAAIADLEPMLVDNQATLINLVTADLPLVNADPTQVWRVFSN
LIVNAIKHNPPGLHVTINAIPQDDEIYCTVNDNGVGISQQQSDRLFDLYF
RGGSIRNSLGLGLGLYLCKQIINAHGGEIGVKSGLEKGATFWFTLPMTSN
QVNQL
>Ava_3850 Periplasmic Sensor Signal Transduction Histidine Kinase
MLARRTKLLSQNSFLVKASVILGLLITVISMEFSTPTEYVFGYLYTGPIL
LANHWFGRIATLLTTFIAVFLTIVNLWLPDHEVIRFPTVASRTIACMSLI
VTGILSDRLRHSQEAIALTRAKLESQEELVRLREDFASTLTHDLKTPLLG
AIETLKAVQQEKFGAVSSAQQPVLATIIRSHQTSLQLLETLLDIYRNDTE
GLQLNLIPVDLTTLAEEAASTLIDLAASRRVHISFNYGDSDWRRSLWVNG
DPLQLQRVLYNLLVNAINHSRRGDRVEVILETQASYQVVKISDTGPGIQA
EQFPHLFERFYQGHSERQAKGSGLGLYLSRQIIAAHNGIIWAENRVPTGA
MFAFKLPVLPFQPSLSASDGF
>Ava_B0209 Two Component Transcriptional Regulator, LuxR family
MSSIPIKILLVEDDELFRLGLRVRLQQEPGLEIVAEAEDGETAIELLKQI
PLDVVLLDVGLPGIGGIEACKQIKQQNPLLPVLVFTSHSQKPLITRLIEA
GAQGYCLKGIAAEKLVLALRSVASGASWWDATATQEIRSSLSYETPQLEP
ENRAKLSNPLTGREQEILSLLAAGKTNQEIAHQLCIAPGTVRVHIHAILQ
KLEVSDRTQAVLVALQKQLIKSQ
>Ava_0012 Serine/Threonine protein kinase
MELDAFNKGAIPLINHPDCSALGYQVIRELGRNQEEGRITYLAHHHSKQQ
VVIKEFSFAHTYADWFGVTAYESEAQILQKLNHPRIPRYLDSFATQTAFY
LVQEYKHALPLSSKRSFQAEEIKQIAVSILEILVYLQQRIDPIIHRDIKP
ENILVDDQLNAYLVDFGLARVQDTKIALTSLLTGTPGFIPPEEQSGYSLS
LASDLYSVGATLVCLLANIRSVDIDKLINSKGYFDFQKLDSPIDLRFRSW
LMGMVEPKWQYRYANAADALAALQPIQVTGNATAMEILATVIKLKYQTTV
LCLAIIGVLAVAGATLILSQQGGTAQQLQEARKSEVL
>Ava_4914 Two component Transcriptional regulator, Winged helix family
MAPAKILVVDDDPAVRNLIQRFLIKQNYQVEAAEDGKTALSLFEQFNPDL
VILDVNLPDVIGFNLCQEMQSRNGVFVLMLTSRADEADKIRGFAKGADDY
LTKPFGLGELEVRVGAILRRQRVVTTAEQKRLTFEKLMIDPVRREVTLNS
QAVPLTALEFDLLHFLASHPGRVWRRAELIQEVWDYEYVGDQRVVDVHIG
QIRKKIEVDASQPALIQTVRGVGYKFECPTHSQVETNA
>Ava_2524 Multi-sensor Signal Transduction Histidine Kinase
MNINPVDSAIKLKQQSHPHILFGTEVDEHSSGEQLLLSMYDSVQTSIFVV
DVLQDGDFQYVALNPTHERWVGIRSEDLRGKKPEDILTAVDAAKVRQHYA
DCVRFGKTISYEQCLQFQGVSTWWSTTLTPLRDTNSKIYRLIGTSSNITA
AKQTAQAREIQAEGAQILAAIAQRIQESLDLETILYQTAKDLRQCLKCDR
ILIYQIKSDNNGAIVAESTVLPDISLLGKHFRDPCFQGKNKESQGRCCLE
IIEDIYAAGVKPCQRDFLASMQVRANIVMPIALKPDLWGLLIAQYCYEPH
QWQQIEIDLLKQLATQLGIGIQNAKLQQQLKQLQAKLTTHKHEQQAQVKQ
TDKFQALVLNITEKTRDYGEETQVLATVTQELANLFQLESCYIELYSTDC
TVASVVHEYAANQPTYQGLTRQIADFSEIYEPLLQKQHFQTIEIVPGWHP
QLLVITQLACPIFDAQGMLGNLWLIRPIQQMLTQSEICLVQTLANLCAIA
IRQAKLDATNQARLKKLEQRENLTNKFLRKLSQELRTPITSISLAAQTLE
TVLSPSITLDEIIPQLLQILHNECGRESKLINDLLTLTYLQTKPEPPTLI
SIDFQTWLPPIVESFRDLTSCQQQRLHLIIEPGLPRLETDITELERILTE
LLSHTCKYTPAGESITVSAQLTDNTVQLSISNSGLEIPTHVRSRIFEPFY
HISNNDPWKYSGTGLEMALVQKMVRHLGGSISVESSHGQTTFMIRFPASL
S
>Ava_2563 Periplasmic Sensor Hybrid Histidine Kinase
MWRKFQAFIQRTRTVLIITPSVALTIIVGQSLGIFNLLEWKLRDEWVRLR
SCEANTLLVCSHNTIADEIIIVTIDERDIQSVGKWPIPDSSLAELLEKIR
SQQPRAIGLDLYRDLPEGKGHEQLVEVFHTTPNLIGVEKITGERVNPPPA
LKKNDQIGLADLVLDGDRHVRRALLTAVDTQEEGKIKAGLATLVALKYLE
AEKITLESVDAKQQKFRLGKQIHLPLQNLSAGYTDSDLGGYQILLNWYGS
EAAFRTVTMRHVLAGKIPPELMRDRMVFIGSTAASTNDFFSTPFSSSLMS
AQKPTPGVVIHANIAHQLVRGARTGKANLRGVSGLSMAGWIILWSVIGSS
GSWLLASARSGRRIPGGKILWTTTSISGAFLGGGYGMFLHGVLIPVTPPL
AAFIVSVIATTNAYKQQKLEEANQQLEIANSQLLDYSKTLELKVQERTHE
LLEAKQAADAANQAKSEFLANMSHELRTPLNGILGFAQVLEVSPNLKEKD
LEGVNIIHQCGSHLLLLINDILDLSKIEARKLELVEANVHLLTFLHGVSE
ICSIRAAQKGIAFKVSVGDRLPTVIEVDEKRLRQVLINLLGNAVKFTDSG
EVAFKVELLDTQDQDNQQSSVAKLRFQIEDTGVGMSPEQLEKIFLAFEQV
GDYRRQSEGTGLGLAISQRIAELMGSQIQVQSRLGEGSIFWLDLTLPVPI
AHDWQTYAPTHQKIIGIQGNAPQILIVDDDDNHRSMLNSLLQEIGCQTLE
ASDGKQGLQMAHEHHPDLILLDLAMPNMDGFELMVQLQENPQTSSIPIIV
SSASVFEENRQRSLQAGATAFLPKPLQIDELFNALRSVLQVEWIYTPSAS
LSLSPQPEHTTHTELVLPSQDVLQELYHLAMMGDIPAIEGILRELIQHNS
QLAPFATELSKLTTNFQTAKIRQFLKSFVITESHP
>Ava_A0003 FHA domain containing protein
MITCTACGYDKNPDDAEYCDACGSELQTVAAPTSTSSVAPTVLQSPIIEQ
EIPAPQIPQPTYPTSTPTSPTFSTTATTAKLISKQPGSPIAEFSLDSNAV
VGIFDPDMGPVDIDLEEFPGGNTVSRNHAEIYIEGGVWKIKDLGSTNGVF
IKQSSQTRFGARITVPETINFGDEIAFGKVRFLFQST
>Ava_1849 hypothetical protein
MPPIPHYLTFITVILVVIPSVITIFLRFKLYQHLVSLEEKVRRLINRQSR
GQQPKILEELESRFQQASNNLDQVNTVALIDQVYSREKINGFTCEQIDYW
CRILPNLLLAFGLLGTFFGITSNLAEISQTINQNNSNNVNDLVSALNKPL
EGMSIAFVTSLTGLLFSSILTVFNWLKNTGFAKYRLISSLEDYLDNIYQP
EIQGDTRLDKIVNRMVSQQDEFLTRFGSTVRDAVEQSLGNVAKQIAQGNK
EASDLAKQVYESFYQAAGTISTAASEFDHSIQELNAKSQIFKQSAEIFER
SQFPQQLSAATADLSSIQLKFSQSATSLADTVKSFATVLSEVQSCNQELI
KIGLDIQKVNQTSLQVFDLHQSNQDALTEIIPQLKQGTTSFSRAINKLGK
LEERIVDKADSFNTVEVTLRELLLSVNQYTEKANSGLSNVSKKLEDNNLS
VNNLVSNVEELIKQITFDLNTLINEIHSLQNSNNALFVKHEKVGDHLIEA
MNKLNNINNNTFVYKDVNLSNDHS
>Ava_B0233 conserved hypothetical protein
MSCIHGNYEALDAVLLDIDQHSCEKVFCVGDLVGYGPHPNAVISQIRSLD
IPTCAGCWDEDIVEGLNACDCSYPSLLAEKRGIQAHEWTNKEIYPENREF
LAQLPYSLKEGNLAFVHGSPYSNHEYLLPELDAFVALERVLSTDSDVLFC
GHTHVPYARTLDAGQLQVHVGRGEKVQEINFTSPLKRIVNVGSVGEPRHG
RPNATYVIYDTDTQEVKLREIPYDYQKTCAAIIEKGLPTIFAWRLAHGLE
YAERADDPTHVCTR
>Ava_4989 (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA
MSSIAISSPTDLSLPEWLKQCLRDSSTYGSKAENDRMCSDNTLICRAFDF
AYQLHHGQYRKSGELYISHPIAVAGLLRDLGGSPAMIAAGFLHDVVEDTD
VTIEEIEERFGPEVKQLVEGVTKLSKINFKSKTESQAENFRRMFLAMAQD
IRVIVVKLADRLHNMRTLQYMSEDSRRRSAQETRDIFAPLANRLGIWRIK
WELEDLAFKNLEPEAFRQMQKYVSEKRDAREEKLAKATAILRDRLQQAGI
RCLDISGRPKHLYSIYQKMHRQQKEFNEIYDLAALRIIVETNEECYRALA
VVHDAFRPIPGRFKDYIGLPKPNRYQSLHTGVIGLTGRPLEVQIRTMEMH
RIAEYGIAAHWKYKETGGSNSLITTSDEKFTWLRQLLEWQSDLKDAQEYL
DSVKDNLFEDDVYVFTPKGDVIPLSPGATTIDFAYHIHTEVGNHCAGARV
NGRMVPLSTRLSNGDIVEIITQKNSHPSLDWLNFVRTSAAKYRIKQWYKR
SRREENVARGRELLEKELGKTGLDSLLKSDAMRTVSEKCNYHSAEDLLAG
MGYGEVTLNLVLNRWREVVKSQQPVVDTPILLPKEPSTAKAPTPITRATD
SPIVGVEGLVYHLAGCCTPIPGEPIIGAVTRGRGISIHRQGCHNLETVEC
DRLVPVSWNPVAENRGRPQTYPVNVQIEALDRVGVLKDILSRLSDQGINV
RYAQVKTAVNQPALIDLGIDIRDRPQLEQVFIQIKKMSDILNIRRVGQID
E
>Ava_4149 Putative diguanylate cyclase (GGDEF domain)
MQHDLLGSIRTKLIASFLVVALIPLLLLASINKQTTETALTDNARQALSA
AANQTSNRIDAFIDRNLNAVRVEALLPGLAGYLSLTPKARDDSPEMQLAT
ETLNRLSRKDMVHIISYGLLDLKGKNVLDTYTYTSDISEDESDQDYFQKP
LQTGLSFASSMKRSPIIPELITIFFSSPVRNAQGDILGVLRVSYNATVIQ
QLVNRETELAGAKSFAILLDENHIYLAHSHAPQLLFKSIVPLPFDIITQL
QREGRLSNDPIRELATNELKLKQALNNKKLHLTTTLSTTGNQVNLIAIAS
LKYKPWSVLFAQPLVVALAPVEKQIHDAMFLFVLIASVVTIIAFAIGQLL
TRPIIYLTNIVFQFTTGNLNIRAKISSTDEIGQLAKSFNNMAFQLQTSFE
TLEQRVQERTAELVIANQKLEQLVNLDGLTQVANRRCFDERLKAEWKRLA
REQQPLSLILFDVDKFKSYNDYYGHLGGDDCLITIAQAVQQKLHRPADLL
ARYGGEEFSILLPNTDLLGAIKVAQIIQQAIYDQAIPHAQSDIKDIVTLS
LGITSIIPAGDINPDTLIASADKALYNAKQQGRDRYCTHET
>Ava_1486 Histidine Kinase
MNWSNWVYLGAGLLFGLGVRGLFARSTNSTASQSTVTPEEQEYTLQLQQQ
LQQTQLAYEMAQEMSQFKGGFLARTTHELRSPLNGLIGLHQLILSDLCED
PAEEHEFIAQAHERALKLLHLMDEILNVAKAEHGNNKLDIQPNSLAEILQ
EVYKLTYMLAVDRNLKLQISPPDPEIYVLADARWLRQVLLNLVDTAIGQM
QEGSIFISAKLAPESKDVSIWLDLPSHTVVKSESIDLLQMTDESSPKDKQ
NTRLSPSMKLLLNQKLLTVMGGKLEILPSSESHPAEQLTRLELSIPLAIP
EAELL
>Ava_B0197 Osmosensitive K+ channel Signal Transduction Histidine Kinase, sensor domain
MSNPLPISANSTYTHPSRYGKHKILLGMAPGVGKTYRMLDEANRLKQQGK
DVVIGYLETHGRIDIAAKAIGLEIIPRKIVQQGELILTQMDTDAILARQP
QLVLIDELAHTNIPESGRDRRYQDVEAIVKAGIDVYSTVNIQHLEKFSNL
VTQMTGIVEQECIPDYLLEVANEVVVVDVTPETLEERLLDGKIYPLDKIE
RSLQQLFQHRNLVLLRELVLRELADKIEQKAIKEAGYTSLAQACCVHERI
LVCVSTQPHSLQLIDKGAKMADCMKAPLYVLFVSDPQHFLTKEEELHIQS
CKNLCQKFNGEFVQESSHNVAEKIAQVADFYRITQIVLGQSCHSRWQKIF
RGSLISQLMHILAHRLPNAAIHNSNSKQAICDRTSFSQIDFHLISI
>Ava_2805 Response regulator receiver domain protein (CheY)
MKLLVKALTWIQSLKPSDLQEPNRDFNYIKLKIFTTETSEPNCEYTQIIK
HLIIDRDISMVNVDQLIMSQDSPQSSTLKILVVDDHQLILSGTLNVLQQQ
YPDAAISTAKTVVEALTQMRNSAFDLIVMDLSIPEKTGAIAYIDTGINLL
QQLIQEYPQQNFLVQSSYVKALVRIKHEIDEHQGGFAIADKGLCESEMIV
RANLALQGATHTKDIKTGLELKPEWLEVLKLAFEEGLTDIAICKRIHRSE
RAVRTYWTKIQDVLGIYPEPGKNMRIQTEIRARQEGLID
>Ava_2989 Serine/Threonine protein kinase
MAWVAGGQLQGGKYTIERELGRGRFGITYLVTNRNSDRLVIKTLNDNLLQ
SLSQPQRARLENMFYSEALKLQKCHHQHIVKIIELFREAEYPCLVMEYLG
EDSLANLRPAILSEQDALRYIQQIGEALIVVHKNGLIHRDVRPENILLRK
RDGNLEAVLIDFGLALDFDYILTTSRTQETSAGFTPSELSTQGTIAKACS
DVYSLAATLYKLLTGRTPVDAVKRKLNGEHLVSPKEYNPQISDRTNRAIL
TGMQLDPKQRSQSMREWLDLLGLTQPETNVTSDTKSNWERNIQMWGIIVA
AIAAIGTLLSGIVGWIPIFKPSSPPSPSLVSPSQSPSQTP
>Ava_0084 Serine/Threonine protein kinase
MLGTLLVGRYQIRQMLGGGGFGKTYIALDTQRPGQPKCVVKHFQPVTHNP
EFMETARRLFTSEAETLERLGYHDQIPRLLAYFEEHQEFFLVQEFIDGHS
LKAEMPPNQPWTEKKVIALLQQALDILQFIHLHKVIHRDIKPENMLRRLH
DGKLVLIDFGAVKEVQTQISAISGQTEMTVAIGTPGYMSLEQFRGKPRLN
SDIYSLGIVCIQALTGVHPRELAEDPVSGEILWQNSAEVSPMLASVLSKM
VLNNFKLRYQSATEVLEALQQNFHLQAETQITVAPSTLTQQPQLSLSQQQ
RLGLHSSNSSILSVEQYNYLENVLTTFVGPIAATLLRRTASASSYQELID
SLALHLTANQQTEFKKKVEPLLEQPTIKYENTSKSVPEKTQPTTNSGIND
TLIRECERELLDLIGPIAVFLIQKAKKSTSATTSRAEFIKIISDEIPDAQ
KAWQFQQRLLP
>Ava_4345 Multi-sensor Signal Transduction Histidine Kinase
MKSPLHNEQARLAALRQYQILDTEPEEAYDNLAQLAAFICGTPIALVNFI
DENRQWFKAKLGIDVPEMPRSVGLSYLCQEKQGVVVIPDTLADDRFIDNP
VVKSYPHVRFYAGVPLLTPEGHFLGTLCVIDNVPKQLNQPQIDALAALSR
LVISQLELRRNVAHVAQVSELLIKHEQAARAESETARKQIANILESITDA
FFAIDYEWRFTYINGQAAKLLEKTPDELLGKSIWEVFSDTLDSTFYRETR
RSLTKQISVKFEEFYPPLHKWFAVHAYPSKDGLSVYFQDISERRYTAAAL
RESEERWQLALIGNNDGIWDWNLKTNEVFFSSRWKQMLGYEDDEITHHVD
EWSKRVHPDDFDWVMQAVQDHLGKKTPYYVTEHRVRCKNGSYKWILDRGQ
ALWDEAGNALRMVGSHTDITERKQTEEELKKQNLRSQLFAEITVKIRETL
DIEEILRTSVQEVQKLLQADRVLIFRLWADGSGTVVQESVLPGWPVVLGQ
NILDPCFQQDYVDKYRQGRVSAIVDVTKAEIQDCHREFLQGFGVKANLVV
PILNRDGIWGLLIAHQCTNHRHWNNSELELLQQLANQIGIALSQGQLLEL
QTRQSQELARSNTELENFAYVASHDLQEPLRMVTSYLQLLERRYKNQLDS
NAEQFITYAVDGARRMQTLINDLLNYSRVTTRGQPFVAVDCGVILQRAIA
NLKIAIEESGAVITNDPLPTLMADPTQLTQIFQNLIANAIKFRQEASPVI
HVGVGEVGGRGQEEKSQGGFPSGRTSGAGEAGGERPNPQSPVPSPQSPVP
NPQSPVPNSHTTWLFSVHDNGIGIEPQYADRIFIIFQRLHGRSKYPGTGI
GLAICKKIIERHGGHIWVESEAGQGSTFYFTIPEQTGKKS
>Ava_2930 Phycocyanin, beta subunit
MTLDVFTKVVSQADSRGEFLSNEQLDALANVVKEGNKRLDVVNRITSNAS
AIVTNAARALFEEQPQLIAPGGNAYTNRRMAACLRDMEIILRYVTYAILA
GDASVLDDRCLNGLRETYQALGTPGSSVAVGVQKMKDAAVGIANDPNGIT
KGDCSQLISEVASYFDRAAAAVG
>Ava_4723 GAF Sensor Signal Transduction Histidine Kinase
MSISTSVLSDLLQSLPYLRPQLYFKASLTALSHAMEDQVLAATLDQPLVI
ASFQRERFYRQEAHRYQRLAQRSNQIYVLSAPETDFANSSEYYEKVAFEP
DDALSQEWHLVVVADNYATCLVCRESLGSIAKNQQIPEFSPGLDMDAGRR
FEGIWTSERGVSIKAAQLLLDRILVYRPDLAKKVTKACQRFGIGEKKIYS
NATSVLTEYACDIDTDPFVQRLVTYLQASQYKLHKAYRSIAAQARKERLV
NSISTAIRRSLDPHQVLQIAAQELGQHLGASRCLIYRAQASDAQAVIEHE
FLTPGTVSISGQTWELKNNSLFKEVVDHGEGVCVTDTLNDFRITNSPTLS
LIAKKLAIRSWLIEPVVFQGRLLGIVELHYCALPPHQWQPGELDLVEAIA
TQIGAALIQAEAYANLEELNQQLEALDRTRSNLIAITGHELRTPLSTIQV
CLESLATEPDMPVELQQVMLNTALSDSERMRKLVQDFLTLSNLESGRVEW
HPESLTLQECIDLALSRLRIRPGVEKPPAIKTQIDGNLPLVRADGDWLVE
VLAKLVDNACKFTPTQGEIKISATHNGSQMVEVTVADTGRGIEPNRLEIV
FDRFYQEEGALRRTAGGTGLGLAICRQIVNGWGGAIWAASTGKDQGSQFH
FTIPIAQNSQEESWSKVKSR
>Ava_0123 Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with Response Regulator Receiver modulation
MNYKQLDPYKKDILIIDDMADNLRVLSSILAREGYNVRKALNWQMACTAC
QTLLPDLILLDIMMPEVDGYEVCQRFKAWELTSDIPVIFISALDDVFDKV
KAFKVGGVDYITKPFELEEVLVRVKNQIELRTARIEILTLNAELEQRVKQ
RTWELEKALQKLQIEVSARQKLQGKLLDMALHDALTGLPNRILFIRRLGK
ALNRAKEESNYQFAVLFLDCDRFKVVNDSLGHLVGDELLISIANRLQSCL
TTDSTLARLGGDEFGILLEDIKDIRMAIQIADYILQQLSMSFKLSRYEVF
MNVSIGINWGHQGYDQPEYLLRDADTAMYRAKDSGRARYHVFDPAMHEEV
IKALEKENDLRRSVEKQEFVIYYQPIISLTTGKISGFEALVRWQHPTHGL
IAPTEFIPVAEETGLINIINMWVLQSACQQLRIWQSHPMTPKNLSISVNL
SAKLFLQTNFITQVDQIIKDTQIDPSNLELEITETVIMENNNEIKVILQQ
LKERKIKLIMDDFGTGYSSLSYLHIFPFNALKIDKSFVNRMLDNQENMGL
VPAMISIAASMGMSAIAEGVETQEQLEQLKSLKCDFAQGYLFSRPIAQNM
VMDFIASATKW
>Ava_0619 Metallophosphoesterase
MSCIHSNYEALDAVLLDIDQQKADQIYCLGDLVGYGPYPNAVVAQIRSLD
IPTCVGCWDEDIVEGLNSCECSYPSLLAEKRGKLAHEWTHKELHQENQEF
LAQLPHTLRQDNLVFVHGSPQSNHEYLLPELDAFAALERVFSTDADVLFC
GHTHVPYVRTLDAGNLQVSVKGVGIEQKAINFSASVKRIVNVGSVGEPRH
GRPNATYAIYDTDTQEVNLREVPYDYQKTCAAIIEQGLPPIFAWRLAQGL
EYAERADDPTHVCTR
>Ava_3735 Adenylate/Guanylate Cyclase
MSLQQRNFGETGDLILGTQNQEQNLPATSAPVGTLARRKGTISTFLAPLT
QDTFKQVVTEVEQKLQIVHQTLSMLDSHGFENILQEMLQSITLKTGELLG
ADRTTIFLLDEEKQELWSIVAAGEGDRSLEIRIPADKGIAGEVATFKQVV
NIPFDFYHDPRSIFAQKQEKITGYRTYTMLALPLLSEQGRLVAVVQLLNK
LKPYSPPDAVLAERIDNQGFTSADEQLFQEFAPSIRLILESSRSFYIATQ
KQRAAAAMMKAVKSLSQSSLDLEDTLKRVMDEAKELMNADRSTLWLIDRD
RHELWTKITQDNGSTRELRVPIGKGFAGIVAASGQKLNIPFDLYDHPDSE
TAKQIDQQNGYRTCSLLCMPVFNGDQELIGVTQLVNKKKTGEFPPYNPDT
WPAAPECFQASFDRNDEEFMEAFNIQAGVALQNAQLFATVKQQEQMQRDI
LRSLSNGVISTDKAGTIIAANESAQRLLGLDSEDRLEGKLISEAIAIKEG
DFSKWCQDALHGTDLKRRQQYYPDRTLVSTEAAQNSINLSINTIADASDP
QQVCGALVVMEDISDEKRLKSTMYRYMTQELAEELLKLDDAKLGGDRKEV
SILFSDIRGYTTLTENLEAEEVVSMLNEYFESMVEAVFKHKGTLDKYIGD
AIMAVFGSPLPLEEHAWMAVKTSIEMRHRLQEFNQRRYAANKPRINIGIG
INSDTVISGNIGSSKRMEFTAIGDGVNLGSRLESVSKQYGCDIILSDNTF
KPCQENIWARELDFIRVKGRNEPVSIYELIGLRSDPIPSEKLQVIEHYHK
GREYYLNRQFPLARAEFANVLAVDKHDKAAMLHLLRCQHWLQSPPTNSEW
DEGVWTFQEK
>Ava_1626 Response regulator receiver domain protein (CheY)
MTIKKILLIDDEPTIRELVKICLNDLVGWNVVTAASAQAGLKHLEIERPD
VILLDVLMPGMDFTTFLHRLHGNHSLKTIPVILLSVRADWFTSQQLQQLG
VVQAIAKPFNPLTLPDQITRALGWSFHPEYEFTL
>Ava_0663 Putative Anti-Sigma regulatory factor (Ser/Thr protein kinase)
MKSELHVPSDLNYLNIVEHWLLGCLKIQLGESVDWSRQSSRLRLALVEAY
SNVVRHAHKEQPNLPVLLRLEFKERDIALEIWDYGTGFDMSTYFPPNPGD
RQEGGYGWLIMNRLMDKVEYQLQVDGANCLKLEATIPELANN
>Ava_3819 Multi-sensor Hybrid Histidine Kinase
MSNIQRSHLQRYCISIVSVLLSLLLGLTLGRYLIEISPLFFASVVFSSWY
GGLVPGLVATVLALLVKNHFFNTPFNSIAVSQGNDLLNLIVFASVAVLIS
SLNLQVRTAREASEVQLAKLKVNYRHLLETANEGIWIFDSEGKTEYVNHQ
LAQMLGYSVEQISKCSIFNFLEPQARVEIEQWLEQQHKYHQQTKQQFDLR
LQRHDGASLWVIVSLSSILDKHGQFSSAIAMLTDITEHKQEPAKPDLERQ
RLRAILDILPMGVVISDAKGQLLEINPGAKAIWGEDAPLLDNTSQYHQYK
GWWPDTGQPLTAEEWTLARTLATGEAIIGEEIDIETFNGERKTILNSAVP
ICDATGTIVNAITVNVDITERKRVEAALRQSEALAKARAEELETIMETVP
AAVWIAHDPHCHSMSVNRAAYEMMRVPAGSVMTATPASGGYPFPFKIQKN
GQDVPLNELAMQQAGLTGQEVEAEVEFVFSSEDVRHIYGKATPLCDPDGN
VRGVIGAFLDVTERQQLMSLLQQKQEWLDLAQKSGKIGSFDWKLASNINI
WSQELEEIYGLQPGEFGGTFEDWAKRVHPDDLARVKVELQELLNTGSKEF
FSDFRIIRQDGSLCWLQSRARVFYDDHGQPLRMVGVNIDVTERKQAEAAL
QQSEARLKQLLQSSIIGIIEADSERINFANDAFLKIVGYTQEDLLTGKLR
WQDMTPLEYSELDQAKVQEVINAGFCIPFEKEYIRKDGSRVPILLGAARL
SSSPLTWVCFILDLTARKQAEAALQQSELMFRTLADTMPQMFWITQPNGY
HEYFNQRWYDYTGTTLEQTQGEGWQKILHPDDVQRTIEQWQDSLDTGKDY
DIEYRLRRAADGEYRWHLGRAFPLRDENGQMVKWFGSCTDIHDQKLAIEE
RAQAWEQERAARIELERANRMKDDFLAIVSHELRSPLNPILGWAKLLKSR
KLDALKTNQALEVIERNAKLQAGLIDDLLDVSRILRGKLSLNVCTVDLVT
TIEAALETVRLTAESKSIHIQTDLTASVCRVEGDPNRLQQVVWNLLSNAV
KFTPEGGEIEVKLERVGSLAHIQVRDTGKGISLDFLPYVFERFRQADEVT
TRKFGGLGLGLAIVRHLVELHGGSVQVTSPGEGLGTTFTVKLPLVAVSQI
YEEHFIPDTTPNLQGLRMVVVDDDADTLELLSFILEQYGVEVKAVNSANE
ALEAIAQSKPDLLLSDIGMPEVDGYMLIKQIRSMEVALGTKLPAIALTAF
AGETNFQKIMSAGFQRHLTKPVEPSELATVIANLIQSNTNLKKASDK
>Ava_1530 conserved hypothetical protein
MANNIKQQIQADLQQAKATGQLKSERIREIVKTAVSQVASEFKEGSSEIR
SLVKDAVSTVIENLQDKGTEIKEEVTASIEGAIEGVNTKRHAAIVRSQSE
LQRLQAQIDGEEEKIQQEVDGILAEIAENGQQETASRRTVIDSAIDSIKN
SEEVSLLQKRYAQLQAQLSIVRANLAARYGGRSEEVKNYLDEAKTWYEQA
RPQAEALATQVEEKRSQIDSKLGEAGTSLARKERQIKQTLRELLLATADL
FKDKEHPEQEKEVTRK
>Ava_1423 Response regulator receiver (CheY) and GAF domain protein
MADAVTEIQTGRRQSATLERTKKLKILVVDDEPDNLDLLYRTFRRDFNVL
KADSGVNALEVLAAEGEVAVIISDQRMPEMKGTEFLSKTVPQFPDTVRII
LTGFTDIEDLVEAINAGQVYKYITKPWDPGELKAVVQRAAETYDLLKQRT
EELRRANAQMSLLTVLVQVTQASNSLETILTPIATAFAESFAVNACILQM
LEGQTLSTIQGFYSQQGTVNNWLNQDPLTNEAIATGQIQVAANIAKDPKL
ASISQYQDNGIQAHVVIPITYRNEMLGVLSLQWQQPISLREDELTLIHLS
AQLVAIALTSSRCSL
>Ava_3852 Multi-sensor Signal Transduction Histidine Kinase
MRIDLESPNINVTSLKEAPIHLSGQIQPHGVLLVLEEPDLKILQVSNNTW
SILGIKTEDILQKKLEDLLDSFQIERIQAGLSSGNLEFINPTKIWIRKKG
DDYAVFDAVFHRNTEGFLILELEPAITQENIPFLSFYHLAKASINQLQKT
ANLRDFCQIIVQEVRKVTDFDRVMLYKFDDDGHGSVIAEEKLDSLEPYLG
LHYPESDIPKPARKLFISNSIRVIPNAQAQAIQMIPSVNPVSDRPVDLTN
SILRSAANCHLEYLHNMGVGASLTISLIKDNKLWGLIACHHLSAKYVSYE
LRKACEFLGRVIFAEISAREETEDYDYRMNLTHIQSLLVEYMSQEDNFVD
GLVKHQPNLLDLTSAQGAAVCFGDHCTLIGETPKAEDLVFLVQWLKNNVE
EEVFYTDSLPQVYPDAERYKNVASGLLAIPISQRNYVLWFRPEVIQTVNW
GGDPNQPFEVNKLDGNVRLCPRKSFELWKETVRLTSLPWRYVEIKAALEL
RKAIVNIVLRQADELAQLAQDLERSNAELKKFAYVASHDLQEPLNQVANY
VQLLEMRYQDELDADANEFITFAVEGVSLMQTLIDDVLAYSKVDTQAIAF
QLTEVEKALDKALGNLRQRIAETGATITHDPLPTVMAGSTQLMQLFQNLI
ANAIKFHSQEAPQIHIGAERLEDEWLFSVRDNGIGIDPQFSDRIFVIFQR
LHTRDEYHGTGMGLAICKKIIECHRGRIWVESQLGEGATFYFTIPVGGRE
RERRNGRKTQNNLFS
>Ava_3340 Transcriptional Regulator, Crp/Fnr family
MINFLNIDQLPENIKMAMAITYESLAAGQPLFHQGDLTRAIFVVTSGQIR
LMHYTDAGQSIKHYEVKAGESFAEAALFNEFYDCTAIADIPSRVATFPKQ
PFLATLRQHPDLSEALIVQLVRRFHQVKILLELRSIRSARDRVLRYLEIA
AHPHGNIVNLDKPLKEIAEDMGLSQEALSRVLSQLQKDGAITRKKRQIIL
VQELYRT
>Ava_2473 Glycosyl transferase/Transpeptidase with FHA domain modulation
MNSPQPPHKPQTLLGQLTQAVNTIQARVDFSKLALKPNAKVPELWVQDAG
ADKAEVYPLLGDRYVLGRSSKSSDIVIRNPVVSQIHLSLSRDSSQRTPVF
IIKDENSTNGIYRGKRRVHTLELRHGDILTLGPPELAASVRLQYVDPPPW
YVKAATWAGYGVGGASALLALVIGVEWLKFSVRPLPTTTRAPVVVYARDG
STPLREPRTVSHVDMKRLEDFGPYLSAAVVASEDSRFNWHFGVDPLGILR
AVLINTRSGDVQQGASTITQQVARSLFRDYVGRQDSLGRKLREAIVSLKL
EAFYSKDEVLLMYLNRVFLGADTSGFEDAAQFYFDKPAKELTLAEAATLV
GILPAPNAFDFCGSGPNKLEAADYRNRVVKRMLEMGKVTSEEANRARRST
VQVSPKVCEQQAKTIAPYFYNYVFQELEAILGEGAAREGNYIIETQLDPA
IQTQAETALRNSVSTAGSTFRFSQGAMVTLDSRTGSILAMVGGTDYRTSQ
FNRAVQAKRQPGSTFKIFAYTQALLQGIPASRTYSCAPLTWQGFTYRPCR
SGADGSLDIATGLALSENPIALRIAREVGLDKVVSMAQRLGVKSQLEAVP
GLVLGQSVVNVLEMTGAFGAIGNRGVWNPPHAINRILDSSDCSDRNDFKT
CRVIYSFDSDREANKRVLPQPIADQMTDLMQGVITRGTGRSAAIGLGEAG
KTGTTDKNVDLWFIGFIPNRRLVTGIWLGNDNNSPTSGSSAQAAQLWGNY
MRRITR
>Ava_2466 Periplasmic Sensor Signal Transduction Histidine Kinase
MQRFFRQLNLSQKIVIPLLIVYLSVFLLGLVVTGHWFTESLEQNFRQDVN
NFTERVYQDFQYEQKTLETEIKLISYQDKLRRAIEERDQDLLLQILLPLR
TVLGLDWLKVVDPQGNVLTDLRSNSLSQVRLLDKLISSSASSGAQLTDLV
DTEDGTQVIQTVTYGIKSATGLLGGIIIGNSVDNTLLRKIATGSSKHLIT
QKNNRIVATTLLAAQQGNWQFPTPDMPVKQIMVNKHNYLAKSILFSGTTQ
ALTTTVLYSTSVLKASQWKLWQHLGFLYVLGSVIVAIAGFLTTRTITRPL
QAVTQVAQRVTQDSNFNLQASVNTEDEVGILAISLNQLIKQVKLLLAEQY
EGQKKLEAYNQTLEQRVEERTQALQQKNISLRNTLQELKLTQTQLIQHEK
MSSLGQLVAGIAHEINNPVNFIYGNLNYTDEYIQQLLNLFQLYQKYYPNP
ELEIQEAQEDAEIEYVIEDLPKILASMKIGASRIREIVLSLRIFSRLDEA
EFKTADLHEGIDSTLLILQHRIKSQTIKAMTYGRQNTITDNLNKKEIVDK
HRPQLEIVKEYGDIPKIPCFAGQMNQVFMNILANAIDALEEAFYDGLCPE
PTIHITSWQVDESVVIAIADNGRGIPQEVQSRLFDPFFTTKPVGKGTGMG
LSISYQIITEKHGGTLQCISSSGQGTKFVITIPIRLAD
>Ava_3854 Response Regulator Receiver Signal Transduction Histidine Kinase
MVGHSVRILLIEDSLAEARLLQEYLHQAESKQFVLVHVTRLQEALNELKQ
TSYDVILLDLTLPDSQGLSSLPRLIGLAPSVPIVVLTNTNDEDLAIEAVR
QGAQDYLVKRQVNVHVLVRAVCYAIERKQALETLRTMNTTLENRVEERTA
ELVKAQEINQFKSEFVSMLSHDIRNPLNTILLAAGLLQNNEDKLTQEKKR
SHLQMIRSAIKNMAQLLDEVSLIGKAESGKLQCELIAIDLEAFCRQLLAE
AQLTIGEKQLTVIFTCNKKFDEALLDETLLRHILGNVLGNAIKYSLPGGM
IHFELTANNNAVMFKIQDCGIGISPQDQKNLFQSFHRGENVGGIAGTGLG
LAIVKKCVDAHGGEIIVNSEVGVGTTFTIILPLINF
>Ava_4203 UspA
MVKNVLVALDGSEIAPRVVQALDELVLSPDGTVVLCHVFPTADSEMELPA
DLPHPESTTGSYFQIEKQLQYYQDKLSVKTELELVTGDPAEEIIRLSNIY
QTDLIIIGSRGLTGMKRIVSGSVSNQVVEEANCSVLVVKPK
>Ava_2420 PAS/PAC Sensor Hybrid Histidine Kinase
MSELLYTFFITITAIIFLYTAFVCVKLIAKAGKFPSNVQLEATNQKLQQA
ILNSANYTIISTTPDGIILTFNAAAQRWLGYTAEEVIGKTTPEIVHDKNE
VVKVAQELSQELGVTIEPGFEVFVAKARLGQVEEREWTYIRKDGSRFPVL
LSVTPLYDAEENITGFLGIGSDITARKLAEAALRESEYRYATLAQTAPVG
IFRNDASGRCIFANERACNLIGSPLEDILGEGWVQSLHPDDRLRIVREWN
QAIKQNLPFKAEYRFRHPNNVINWVISQAIPERGSDGEVTGYIGTMTDIN
DRKRAEEELLHLSQALESAVEGISQLDTQGHYIKVNPAYAQITGYTPEEM
IGMEWTSTVHPDDQEKMMAAYRQMLKNGKVEMEARAMRKDGSAFYKQVVM
VKAYNQQQECIGHYCFMKDISDRREVERLKDEFVSVVSHELRTPLTSISG
ALDLLASKVVPAGSEDAQRMLNIAANNTDRLVRLINDILDIERIESGKIQ
ITPQACNAADLMTQSVEVMEELAEQGGIQLAMSPLSAHLWADPDRIIQVF
TNLISNAIKFSPAGATVWVTAKIPEKSELEKFPNPVILFEVKDQGRGIPA
DKLESIFERFGQVDASDSRQKGGTGLGLAICRSILQHHGGRIWAESTLGE
GSTFFFTLPIFPEEQNQEEEFLHRPHTTPQHPKNSTSPLILHCDDDFSVR
AVMQVILEKQGYQVMTVASGKEAVEKAKFNQPDAIILNLMMPDIDGWETL
ALLKQQPETQNVPVIILSGVTPDHNKELSHDVSDWIIKPPDVKLLCRALE
KATTKQQAIKVLVVEDDPDLAQVLIAMFNRHGISTFYAQKGREAIQISQN
IIPDLLVLDLGLPEWDGFAVVDWLRQHQHLYHVPLVVYTARDLDESDRQR
LKLGETLFLTKGRINPQEFEQRVITLLNRIICN
>Ava_B0252 conserved hypothetical protein
MSDNKFTRQELFELLSASYPPEKIIAGLQELAKTDASIDPNGKEFDVEVS
DRLEKLFNLAETVIDQAKLLGAGGSLTNLQTQAINTAVQQLQAQGITQET
FKAFLEIAAGTTVAQAFAVHNFKTQLFDDISQGLDVQLLQERTQAGVEEI
SLIYQIIKDPQTKEKIISEYGLKTPQQLKNE
>Ava_3666 conserved hypothetical protein
MMANLFSQVITHIKFLFQEFQVKRFFAIALVGFLVLTTSLNSSIDSGRSS
DAVTRRLDKVVHQDNADRPKTTGEWNREARQTEDAPGERAKRIAKESGEA
VKQFGSVYPDTAKRSAEDLQDNNR
>Ava_1816 Serine/Threonine protein kinase
MIMLGEIFNTRYEIQQLLGKKAGRRTLLAKNVVTGELVIVKLLAFSSDFE
WDDLKLFEREAETLKSLSHPHIPQYLDYFEVNSPTIKGFALVQSYISAQT
LEQYLQSGRSFSESDIKQIATAILEILIYLHGLYPPVIHRDIKPSNILLG
ERSGNHVGQVYLVDFGSVQTALGTEGGTRTVVGTYGYMPPEQFGGRTVTA
SDLYSLGATLIYLVTGTHPADLPQKDFRIQFESVANLSPGLTAWLKTMTE
PSVERRFSSAQQALKALESSHLLTHSQLVIGKPKWSKIQLTKDADSLEIL
IPPVGFQPSMVFMGLFAIAWNSFILFWTIGALSAPFPVNIPFALFSLPFW
GAGYFMASTFLLSLLGRNRLRLNREQITFTHELFGWKFHRPRPASKESIT
KLVYISRHLTKDSEGAKTQVPAQLEIWAGVQKYQLGTNTAIQSETELEWL
AQELSDWLNIPIQRE
>Ava_4631 Multi-sensor Hybrid Histidine Kinase
MLIDYQRTKILLIDNSLENWRCLSGFLAETKYSLQRVSTAKISISSVSEL
MPDLILIDSSIDKIDGLSFCQNLKAEKSLQDISILLLTYIEQLSEYSSYF
QIGVSDFISKPLRQEEFLLRMRNQLKIQSKQKNQLEEPHQSFPVVDGLIS
LNNALNQNVISNKKECCWQLSELNNEESINQSLNSHSLVSSNSKITSSKN
NTQEYQTNTVKLYKHNLVLTKLGKNPILYQGNLKTALAEITNVAAHNLGI
ERASIWLYDETLTKIQCADLFEYSRNQHSAGMSLSAKDYPTYFQALHQDE
AIAADDAYTDPRTKEFAQSYLTPLNITAMLDTPIRLAGETVGVLCLEAVK
SPHHWTPEDQNFARSLTNLVSLALEARERQRAEAAHRISEQKLASAFRAS
PDPITLCTYPETRYIEVNDSFCRLFGYSRSQVIGNTDKELNIWVNLEECN
FLSRILEKAKAIRNHEVDFRTSSGEIKTTLFSAEMIEIDGQKYILGTAKD
ITERKQAEAESRLLLLTTQAIARAVDVKSALTLVLRVICQTIGWDFGEAW
TPNRESHVLEHSLVCYCEEASLEEFCHQSQNLRIAPGDGLPGRVWQTKQS
EWIEDVSQVKQGQFLRSPQAAKVGLKAGFGIPILAGKEVLAVLIFFKRSS
ISIDKRLLMLLGAVATQLGSLIERKLIESAHRKSEERLQLALEASDLGLW
DWNIATGKIYRDWQWQKMLGYAQEDIEDDERVIQQLLHPEDLAGVTSAIA
DHLQGVTPVYEMEFRMRCAAGGWKWVQSRGQIVERDEQGQPLRMTGTTKD
ITERKILEKELELREARLNAFFSGAPVGMSIFDDQLRFVQINELIADIHG
KSAQEHIGRTLEEIAPQIAPLVTPFCQQVLLTSQPILNVELSLPAVNQPD
SLRHFLVSYFPIPGEGNQLSGVGKVIVEISDRQRAEEALKESVERERAIA
QVIQRMRQTLDLDTIFTATTEELRQVLNCDRAVVYRFDSQGSGEFVAESW
GKDWISLMETHKNAPHLTENTVQDQSCLAKLLEYTPQSTPDKNFLCVSDI
YQAGFGSCYIEFLERLQAKAYIIVPILSGDQVWGLLATYQNSGPRQWKTG
EINIVIQIGNQLEVALQQAQLLTQTQRQSQALEAAAIAADGANRAKSEFL
ANMSHELRTPLNAILGFTQIMSHDKTLSKDNQQNLTIINRAGEHLLDLIN
DVLEMSKIEAGRTTLNINNFDLIHLLDNLQEMMQGRAKAKGLHLQFEYAP
NIAQHIQADESKLRQVLLNILGNAIKFTETGSIILRVKMGDGDWGLVSQR
GLLYETLREGGFPHVGVSLPVKVQLTNSEGGTEDETKTHLSTPNTQFPIT
NPRFLIFEIQDTGIGICDDEVGVLFEAFGQTEAGRKSQQGTGLGLAISRK
YVQLMGGDISISSTVGVGSTFSFRIQVGLVSAHEIPCQPTARSVIGLAPQ
QQECRILVVDDVADSRLLLVKLLSSVGFVVQEAANGQEALAIWQQWHPQL
ILMDMRMPIMDGYEATHFIRSAETENHTTIPNPHTIIIALTAHAFEEQRQ
AMLQVGCDDLINKPFSEKEILEKLNKYLGIKYLYQEDSSQTLKARTTIFA
HDNLLPLLSTLPRDWVINLYNAAAQCSDDLILKLTEEISCENTALKEYFV
DLAHNFQFEKIMQIVSTIKDVS
>Ava_2027 Periplasmic Sensor Signal Transduction Histidine Kinase
MGQYIKVHNHPFRFLLYLEWILLAISIITSILPYPSPRFSSRFPEITIIS
LTIFGLMGLRLPTSNNLNKIVYTACEIILIFITGLFEGRAARMFPFLYII
LVTRSCLIFKLPGRLSVTLISFSLFLFTLINRLPRPPLPLQAQERFRFFT
LSLTLVFGLSLIFVLLLMNSLLSERQSREELAVANEKLRQYALRIENQAT
LEERNRIAREIHDSLGHSLTALNLQLETALKLAQSNPNKAQTFLVRAKEL
GSKALQDVRNSVSTMRSHPLQDKTLEQAIDIIAEDFQQNTGIILTSSFNL
DYKLSTEVSTAIYRIIQESLTNISKHARATEVILEISLNRGSLSLIIRDN
GRGFDIQQNTTGFGLQSMRDRTLALGGKFAINSDVGYGCQITVDIPASRL
I
>Ava_2712 Phosphohistidine Phosphatase, SixA
MELYLIRHGIAEEQKTGIKDEERELTKEGKQKTEKVAHRLVELGQQFDLI
VTSPLMRAHQTAEILVASGLSCQLEESNHLAPNGNIFNWLDYWLKPRNFP
ENAQIAIVGHEPCLSNWAEILLWGEAKDSLVLKKAGMIGLKLPEIGSPVG
RSQMFWLTPPRYLL
>Ava_1447 Two component Transcriptional regulator, Winged helix family
MRILLVEDDYEQLEPLQGILSEAGYIVDTAEDGEIAEWLISQKDYDLLIL
DWMLPTISGLSLCRQYRCSGKTAPILMLTARDTTPDKVMGLDAGADDYLV
KPADLVELLARVRALARRVPNWQGDSLRVADLQLHLAYLTVEREQLKVEL
SPREARLLEYLMRHPNQVLTRSQIEEALWEWGMEPESNALTVLVRKLRHR
LQQVDAAEWIRTVYGMGYRLNPQY
>Ava_1878 Two component Transcriptional regulator, Winged helix family
MESHKEKILVVDDEASIRRILETRLSMIGYDVVTAGDGEEALETFRKSDP
DLVVLDVMMPKLDGYGVCQELRKESDVPIIMLTALGDVADRITGLELGAD
DYVVKPFSPKELEARIRSVLRRVDKTGASGIPSSGVIHVGNIKIDTNKRQ
VYKGDERIRLTGMEFSLLELLVSRSGEAFSRSEILQEVWGYTPERHVDTR
VVDVHISRLRAKLEDDPSNPELILTARGTGYLFQRIIEPGEE
>Ava_3593 conserved hypothetical protein
MLQETIIDKIYKDNQELLNYLESQQEISLKIQFDTTFKKALLLSVASYFE
EEICKMIQEFVEQVSQNNQYVVSLVKKKAIERQYHTYFQWDGNNANTFFS
LFGQDFKDKLKREIDNDETLKSSVKAFLELGETRNKLVHLNFASFPLEKT
AEEIYKMYQDSLVFVNFLSISFIHKSLS
>Ava_0771 UspA
MFKTVLFPIDQSREAREAADVVTNVVQKYGSRLILLSVVEESSPDESSAD
PMVSPEAVAKLLRDAQALFSQQGISSEIVEKQGKPAFTICDVADEISADL
IIMGCRGLGLTEEGATDSVTTRVINLSPCPVLIVP
>Ava_1567 Anti-Sigma-factor antagonist (STAS) domain protein
MNTNFQVIELSGILDGIRGNQLRREISELIADGNNIFLLDMNAVTFMDSS
GLGSLVSAMQMLRSVNSQLFICSMNDQVKMLFELTKMNRIFQTFIDQDDF
KRQILTATRAIS
>Ava_2328 GAF Sensor Signal Transduction Histidine Kinase
MVEPENKLFALKDGWVSQDTREQQRLKALSELGLRQLETIPVFEEATQTA
AHFLEAPISILGFIDQERHWFKSAVGLSRLGLMNHLAQSRQLLRQESFCT
QVVDSHQILVINDTLRVTDPALATGKLIQDYGIRAYLGAPLIDAAGNCLG
ALAVMDLVPRNFTNRDVEFLQIIARWSMSEFERNRLLMQVKSEQISFKSA
PTFIPHDEPLETQLTPPHVEVEQDSHSTKQVKIELLAQLTQELRTPLTSV
LGMASVLGREIYGPLTTKQREYLDIIQHSGRYLLSLVNEITELGAIDEKA
NVLNVTPVDIEMLCQQAINTLEEAANRREQDIRLSIEPGRSRIWPLDKDK
VRQMLYHLIFSVIQFSATGSIVRIHVSYKENALNITVWVSHPWLGDGITD
VDPYFRLNSLSVMDLAADAATYSVPPEPKEETRSLPVTLEKLRSLADSYS
DLLAVNPDGDSSKSKGNLSRESLGLLLSCQLAELHGGQISIQGSRESGHR
YLVNLPLQLAKAPEVSDI
>Ava_2176 Periplasmic Sensor Signal Transduction Histidine Kinase
MFQKLDIKSIFFKLLRLPFKLLPSQLITLTVVLTLLLFLPQTWVTWQAYN
DFNSIIKNELRLQSLSEKITYYDEVLTMSARMNAVTANSVWERRYRQFEP
LLDAVIKESIQLAPEVYNNQDAKETDLANKRLVEMEYKSFDLVRKGQALA
ARSLLLSSQYESEKRKYASGVNKINQAIAILIDERVLKYKIYLLWSIGGS
VTSLAFLIPSWLLVLRLLKNYLTTSKMAQITLRDLNYELEMRVEKRAKEL
RYKNDQLTQTLQKLQQTQLQLIQTEKMSSLGEMVAGIAHEINNPITFVKN
NVSYVKEYSQDLLNLIRSYQDYYTQPPDIIQVQINEIDLEFIQGDFIKIL
NSIEYGTDRVEKIVKSLRNFSRLDEAEIKSVDIHEGIDSTLMILSHRLTA
IDKHPEILLIKEYASLPLVECYPGLLNQVFMNILVNAIDALHEYNWQRTD
DEIKNSPSRIQICTHQMNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKP
LGKGTGIGLSISYQIIVEKHTGKLYCNSTEEQGTEFVIEIPITQNSSTFT
N
>Ava_5054 Serine/Threonine protein kinase
MQICQNPNCSNPFNPDGNRFCMSCGQSNFGKLLRNRYRVLGLLGEGGFSK
TYAAEDADRLDAPCVIKQFFPQIQGTGQRSKAAEFFKEEAFRLYELGENH
TQIPRLLAYFEQGSSLYLVQEFIKGLTLLQEVQQEPFNEEKIRQLLIDLL
PVLDFIHFHQVIHRDIKPENIIRRDGDGKLVLIDFGGAKQVTQTSIARQA
TAIYTIGYAPTEQMAGFACHASDLYALGVTCVRLLTQCLPQQNPYGHIDD
GLYDPMNGKWLWQEYLQDRGIKISENLSQILDKLLKHLPSERYQSAAEVL
HDLQVSTAIVEETQILPNTQTTLVPLAPATQRTKRPLPPLQTFEYEVVTV
DTAGRIVNRDRTNTQILVEQLNKDITLEMVSIPGGAYLMGSPNFEGDADE
RPQHQVAIAPFFMGKYPVTQAQWRAVAGLPKIKQALNPYPSKYKGQNRPV
ENVSWHEVLEFCARLSEKTGREYRLPSEAEWEYACRAGTTTSFHFGETIT
PDLANFSDGDIHNLEAKTRYRKETTDVGNFRVANAFGLYDMHGLVWEWCA
DPWHNNYNGAPTDGSVWEAGGDIYRRVLRGGSWNFAAELCRSASRSWNES
DGGLRICGFRVVFSPG
>Ava_1593 Metallophosphoesterase
MKITIPELSLVVLIGASGAGKSTFARQHFQQFEVISSDFCRGLVSNDENS
QSASRDAFDVLHYITTKRLAAGKLTVIDATNVQPEDRKTLLQMAKQYHCF
AVAIVFDLPEELCHERNQQRSDRQFGSHVVRRHTQMLRRSLRGLEKEGFR
YVHTLKSPEEIANVEIELQPLWNNKKHEHGPFDIIGDIHGCCDELEALLQ
QLGYEKSGGVENTVWNAPTYYHPQGRKAVFLGDLVDRGTRILDTVKLVRN
MVTADTAICVPGNHENKLLRKLRGKNVKASHGLQQTLDEIAALPEAIRTP
FTKELTDFLDSLISHYLLDDGRLVVAHAGMKQEMQGRGSGAVREFALYGE
STGEIDEFGLPVRYNWAGDYRGEALVVYGHTPIPEAEWLNNTIDIDTGCV
FGGKLTALRYPEKELVSVPAARVYCEPVKPLVENIVTRTSQQEFDDVLNI
EDVLGKRIINTKLQPNITIREENAIAALEIMSRFAANPKWLIYLPPTMSP
VETSSEPGYLEHPSQAFVYYQKQGITEVICEEKHMGSRAIVVVCRDLATA
EKRFGVVDEGIGICYTRTGRRFFDEPGLETQLLARVNAALTASKFWETFN
TDWVCLDCELMPWSAKAQGLIKGQYAPVGVASRLACNDAVELLQQASDRG
LNITTQLTHYQQRAEMANQYITAYRRYCWNVTDIGDLKLAPFHILATEKA
VHIDKDHRWHIEQITQICQSDPDLLLPTAYKVIDLTDPSSQAEGVHWWEK
LTQVGGEGMVVKPMQFLVKGSRGIVQPAVKCRGQEYLRIIYGPEYSAPEN
LQRLRQRGLSLKRSLAMREFALGVEALERFVTHAPLRHVHECVFGILALE
SEPVDPRL
>Ava_2439 Periplasmic Sensor Signal Transduction Histidine Kinase
MGQQAKKDKSQVILFYPDTHKSVKNQQNSIAGTFLKHRRGFFWSTRTRIL
SWYAIILFFIFLVFIPTIRQALYARVNQRVNEEAIEKIEIFEQLLGTSNT
PKHQLDEESIEAIDKLKQNDNRLLKPPTTKQELREFFDAFLGNQLPQDDT
FLIALMDEKFYKSSPRARPKEMDRDAKLIRDWAKLTQTKQEEVVIPNSEV
ESIVYLAQPVKIQSEIMGVIVIAHTTAGERGEVLETLAVIVRVSAFVLIF
ALVLAWLASGKILAPLRLLTQTARKISETDLNQRITIDGNGELAELGTTF
NDMMDRLQNAFISQRNFINDAGHELRTPITIIRGHLELMGNDPKEIQETL
TIVIDELERMNRFVNDLMLLAKAERPDFLLLETFDVCTFTEELFAKVKGL
GDRIWKLEAVARGKIVGDRQRLTQAVMNLAQNATQHTNNTDTIALGSMIY
RDKVSFWVRDTGAGIASADQYRIFQRFARATNSRRLSEGAGLGLSIVQAI
AEAHKGRVTLQSELGAGSVFTIIIPLEPPQEATFIQN
>Ava_4326 Multi-sensor Signal Transduction Histidine Kinase
MISICSQTNKIQAVRVLIVEDEYILAINLQESLESLGYTVVDIADSAELA
IDKATELQPNLILMDIRLRGEEDGIHAAAKIWQNLQIPIIYVTGHSDKST
VERATLTSPFGYILKPIREKELYVAIQTALNRYEREQFLSSVLRFMGDGV
LVVDSQLHIKYMNPVAEALTGWQFDDAQDRNLTEVVQLIDEQTLNSIQNP
IISAIQKQTTVYLGDGVSPTVGHRIMLITKDGTMIPVADSATPLRNNNGD
ITGAVMVFRDDTQRRLTEERNLSAERNRQLEIQMAEMQRFNQLKEDFLAS
TSNEMRTPLSNIKMAISMLENVMNQQGLLKSATASTSASVSRYLGILRYE
CERELTLVDDLINMRIIDTEGYPLDITYIHLQSLLSEIINSFQEIAQAQK
QILQVNISDDLPALVSDKSILSQIISELLMNACKYTPPGERITVTVHFEQ
NQKSLIPEDAQSGLYRASSSPYFQIIINNSGVEIPSTEQSRIFEPFYRFT
YNKTIEKLSVFDQSYQIPQSDYQRTSGTGLGLSLVKKLVQCIQGTVEVTS
GHGLTTFIVQLPLSLSASYSG
>Ava_1353 hypothetical protein
MIEFQILLFTTRYTVIFHLEKSRELTITHLIMLNTSTYYVIAPIDGLHLD
FDYRMYSAEVYGCPPNYVPNPDGCSEFRQPYEYLGSLTFKQYTELSYEGK
IDNQTLRHLEKLPDRKLINFTCIAFEINLDREDYLYLNDEDTNNSLFQYI
LNKGEQLLDVWRLCLFKPGEDFTIGSFGAVGNGIQCFWLGQDDIFPKFIA
RRISRYQLVQQPLDVLLSDFGTIYADITFRNLCYSAFNDVDTSLIKRIFN
ALRAFRESRDIPNWEARFRHLAVIAESLAKKEETEHLRGNELRERIAKIA
SNGWEIYKSYNSSVLSPPGLQARQYRLINKRYKEMGWKNKNEAQKIIKDL
WDNVRNPLSHTVNTVTSLKRNPIEDMVNIEKIIVTMINGICTAYEVEEFY
GSSAYDIILDGE
>Ava_4184 possible Sensor with Chase2 domain
MNKFKSAFISYGRADSKAFATKLYQRFVEAGLEIWFDQNDIPLGVDFQNQ
IDDGIEKSDNFLFIIAPHSVNSPYCGKEIDLALRRNKRIIPLLHVEQITQ
ETWQQRNPGRDASEWEKYQAKGLHSSFPNMHSAISKINWVYFREGIDDFE
KSLAGLLELFRRHQDYVHQHTYFLAKALEWEQKQQQSQYLLIGEEREQAE
NWLKIRFKDEQAPCEPTDLHCAFICQSIKNANNLMTQVFLSYSEKERMFM
EKIAKILMRESFTVWTNKTDIQSGADFTESINRGIEEADNVVFLLSPASL
QSEYCQLELTYAFSLKKRIIPLLLEPVDLEQIPVELRILQFIDFTDQEEE
GKESADTDRLINVLRRDAAYYEQHKILLAKALKWERQKRNPSILLRNHNL
RNAEAWLKIAQQNTQHPPIPLQTEFITESSKQPPEAALDVFISYSRADSD
FARKLNDTLQIQNKTTWFDQESIASGTNFEQEIYRGIESANNFLFIISPK
SISSPYCVTEVEYAMNLNKRIVTVLYRDIGEATLHPGLAKVQWIDFSPRD
TDFLTKFGELTRTLDSDPEYVRSHTRIFLRAKEWEDHNRDNSFLLRGKDL
LASEEWLKQSDHKQPAPTTLQLDYLAASQALPYRKIKLRSVLLTSLAVTT
IVFIARFLGFTQSLELAMYDRMMSLRRDEPQDERFLMVDVDPQSLEALNE
DKRYSGGRGSIPDQALDDVLKILSQSQPSVIGLDFVRDFHAEGSLKERLQ
QTKNLFTVCKNSYVRDSEKIRGFKHPPEVPLARIGFSDLVDDDAKGGRFV
RRQYLMQSPDPKYCNTREAFSLVIARHYLEAQGQKYISPLDIKSKRYVQD
MQFGKTRIPQLLGKGGAYQDINNQLEGYQTMLKYRLSGGVPYNFAPRKNI
LEVLNNQVAPEQIRNKIVLIGFTDRQTRQADYWSTVYGDVAGVTLHGQMI
SQIVSATLDNRQLIWWWPLGYETLWMFGWALVGGIVCWRFNRTLYIGIAV
VGSIACLFIICSVILVYQSGWIPFKPPFLALLGTGAGVLYLTNNLRKN
>Ava_1995 Serine/Threonine protein kinase
MQPPILIGTVLQNRYRIVQILGQGGFGRTYLAEDQRRFNELCAIKELIPT
ATGTVAWEKAQELFHREAAILYQIENPQIPKFREKFEQDQRLFLVQDYVA
GKTYWDILTERQATGKAFTELEVLQLMRSLLPVLEHIHGRGIIHRDISPD
NIILRDSDSQPVLIDFGVVKELATRLQSPEMTTPVTSVGKLGYSPSEQMQ
TGRAYPSSDLYALAVTAIVLLTGKEASELFDENQLSWTWQRWVRVHPVLA
QIINRMLSHAPGDRFQTAAEVAQALQAIDQPNVGVSLPNVSRVQTIAVGR
RPDFAPPPPAPNKSEPVIPPSRSSSVLDSPLALGAIGTAVVILAGVGSWA
LVSSIRSHSSSQPGETPLPQTFPSPVVTGGTTFSTETPEPVVLNKRLNLG
NSNTATVADTIQANQIIRYSFFGNAGDKVTTFIDQGEGVSLTIVGRNQQP
IDSSAQQVTNYVGTLPNTERYTIQLTLASGVAASDYSLNVAIEKAIPATP
TPTPTPTETPTPTLTPTETPTPTSTPTETPTPTPTPTETPTPTLTPTETP
TSVPEPQSLP
>Ava_1191 Osmosensitive K+ channel Signal Transduction Histidine Kinase, sensor domain
MYPVKRGKHKIFIGMAPGVGKTYRMLEEAQALKQEGTDVVIGVLETHGRK
ETADKAAGLEIIPRQQIARGGLILTEMDTDAILKRCLSTSRYGSIPQLVL
VDELAHTNVPGSPREKRYEDVEIILAAGIDVYSTMNVQHLESLNDVVAKI
TSVVVRERVPDRILKEADEVVVVDVTPETLQERLIEGKIYAPQKIQQSLD
NFFQRRNLIALRELALREVADNVEEEAIPGVNATTPNGQFCNIHERVLVC
VSTYPQSLQLLRRGARLANYMNAPLYVVFVANPEHFLTKEESLHIDTCEK
LCKEFAGTFIRVTSGDIGTAIAQVAEQYRITQIVIGESQRSRWQILLKGS
LTHKLVRLLKNIDLHIIATEKTPSARR
>Ava_0792 Periplasmic Sensor Signal Transduction Histidine Kinase
MKGWWPAIKLNTIHSKLLATYLLLIVLGTSCMASYILWSFHVYFMRSRQS
DLENWTNALSESVADALEEKNLQRVNLLVQRYGAPQNLTLRIFNQKGSLL
ATSDPNLDQQVQNWYAVPGMAEALQKRQSQGVAKGILSRKDRLYVAKPIV
RNGQFLGVLRMSITLEQFQRQFARVIVSVLGSLALTIVLCALISTRFARS
LSRPIEIMGNFAIRLGSGQFGDTLTIHENNELDQLAVELNRMSERLASLD
QERRTFLANVSHELRTPISNVQVTVDALKGGAYEEPQLRDRFFQTIENET
KRLSRLIHDLLDLGRLEAGVSQLEQQNLSLSGLINRAVNAMEPRMQAAGV
SLQVKVSDLLIQGDPERLLQAILNLLDNAIKHSQPDSQVLISGYSDGKQA
VIKIQDQGKGIREQDLPRIFEQFYTTDPSRTGKSSGLGLAITKRIIEAHQ
GRITANSTAHQGATFTIYLPLPAKNN
>Ava_1552 Serine/Threonine protein kinase with TPR repeats
MLGNTLVGRYQIISHLGGGGFGETFVACDTHLPGMPKCVVKKLQPQANDQ
ATLEIARRLFDTEAQVLYKLGSCDRIPQLLAYFEENAEFYLVQEFIPGHD
LSKELTPGKVFTQDEVTILLQEILTILEFVHEQNVIHRDINPRNLLRRQD
GKLILIDFGAVKQITTQIVTPTGENKSTVIIGTPGYIPGEQAQGNPKFSS
DIYAVGIVAIQALTGLLPHQLEHDADTHEIIWQNHAQVSSEFARFIDKMV
CYDFRQRYASATTALQALTELTKPASDTIAITPTLPPTKFRFNHTKKSIF
IKLLLAILLISATGTASVFVVNSINSNNATELAKQGNTFFELQRYKDALS
AYKKAVDIRPDYAPAWYGKGKTLFRLKQYQDALTAYDKAIQIQPDYVEAW
SGRGFSLQSLQRYAEAIASFDKALQLNENYPEVWNARGEAFSNLKQYDRA
IKSYDKAIEFKSDAYESFYNKGLALQSLKEYNEAINAYNKAIEIKSDYER
AWYNLGNSLVNLNRYEDAFKAYDKAVQYKTDYAIAWLSKGNVLIILRRYP
EAIESFNQVIKFNPNSYQAWYGKGWSQHQNQRYAEAIESYKKAATIKPSN
YQVWYSLGNSQYILQQYQEAIASYNKAVRYQPKHIESWYSRGNALFSLKQ
YQDAIASYEQAIKHKPDYSQAINARDEAQRQLQAATPKPVVIPVMPTPEF
TNPSQED
>Ava_3384 Serine/Threonine protein kinase
MSDPNIGRLLGKRYQLQELIGTGAMGRVYRAKDVLLGGVPVAVKFLALSM
QNEKMRLQERFEREAKTCALLGQKSIHIVRVMDYGVDENKIPFYVMEYLQ
GHSLNQIIRQQNISLPRFVSMARQICLGLQCAHNGIPVDGTVYPIIHRDI
KPSNILVIQDPSFGELVKVLDFGIAKLLQSNSDQTKFYLGTLAYSSPEQM
EGKELNNRSDIYSLGVMMFEMLTGKMPLVAPTHSFGSWYKTHHHQPPRTF
SEVAPDLAIPQEIESLVMNCLAKAAKDRPSSISVILQVLESVEQQRTKRL
LKQENYDSRQSTATLTINVVSEQKIKPDVLLSAPQDNTIYNTSWPQNKPI
ADIVFPQPINVSGEVLPALWVMLPEKEIFKRIICSRYNQFLFIAAPHPML
LWITVIHNRKYGAKWLPYYLDLKTGIGQEIASLLVKTGGYRLLFFARESP
NRCSHVLSASVASAQRQRLQQWIMTAKTFVSCVDPQMSKNLLKGEYEKLK
PQILAKLAAIDTDSPIDLSG
>Ava_1005 Multi-sensor Signal Transduction Histidine Kinase
MAQPLTVLIIDDCAEDRQVYRRYLQQDQEHHYTILEQESGEEALELCRQL
QPDVILLDFLLPDQDGLELLAELQKLLQGSMPAIVMLTGYGNEAIAVQAM
KSGVHDYLVKEQTTAERLRSTLHSAIIQTRLRQELSRSQEQLHDSQKFIE
RIAETTPGILYVHDLVEKRNVYINGKVGNLLGHTPQTIQNLGKEFLITFM
HPEDLVRLPQVFQQFDSAKDGDIIEHEYRMRHADGGWCWFFSRNSVFMRN
SDGSPRQIVGTAFDITARKQAEEELRSSNERFRLAAAAVNSLIYEWDIKK
GTVTRTEGLTRILGYSVEEATPNIEWWQEQIHPDDQDFLVEQFQNPPVNQ
THYTFEYRIRHKNNQYLYVLDQGIITRDENGQPVRVVGSATDISDRKLAE
AERDQLLQLEKLARAEAEAANQTKDEFVAMVSHDLRSPLNAILGWSQLLR
TRQLDESTFTRALETIERNAQSQSKLLEDLLDMSRILRGKLQLEFCLVEL
PAIIGVAIETAYPSAKAKDIHLKSVIDESIPLIPGDINRLLQVLGNLLSN
AIKFTPPEGQITVQLSYTDSEAHITVIDTGIGIKSEFLPYVFERYRQADC
QHKQHGLGLGLAIARYLIELHGGAIHVNSLGEGQGTTFTIKLPLHQ
>Ava_3723 Response regulator receiver (CheY) modulated Serine phosphatase
MFQILIIDDDISIQTLLKRILQKQGYQIVTASNGEEGITQALTSRPALII
CDWIMPGLNGLEVCHRIKTNPNLSTTFFILLTSLDSVADRVKGLDAGADD
FITKPIEQNELQARVRAGLRLHQLSRDLRTQKLLLEEELAEAAEYVRSLL
PEPLNEPISINSRFIPSRQLGGDCFDYYWLDDDCLALYLLDTAGHGLKAA
LPSISVLNLLRSRALKNLNYYQPSDVLKNLNETFQMNYQNDKYFTIWYGV
YHRIKRQLTYASAGHPPAILISGTSPASTEVQILRTPGMPVGMFPEAQYV
DAYCDVEKLSSLYIFSDGAYEITKSDGKIWSLDAFIQILASVHHNDDYQL
DQILNCLTALNPKDTFEDDLSILQVKFD
>Ava_4645 Adenylate/Guanylate Cyclase
MTELTLRLQQGDTETTVTVNRDVFTIGRLPECNLYLPFAGVSRKHAQLVK
KADGKWIIEDLGSKNGTQVNQSIVSHPRQLQHGDVIWLGNVNLVVMFQKP
VTVVSIEPVPVSDVGEQRTIFRSAKQLQQQWIEANSDDGDISNKNKTIAR
LKDLVDIAKNLCAAASIEEIFFQVQQVVFRYLGSIDRLALLIDVNGCGHL
ELVNAGTRSKTQQQYLLADASWISRSICQKVFEEKIVIQTADTHKDERFS
SEHSILLKGIRSAMAVPLWDENKVVGVLYADAHLSSYHWERDGEEELSFF
SALANLVASSVQRWLLAEKLKTEEVIRHRLERYHSPAVVQQLISIGGLPD
GRLPPAESEISILFADLVGFTAISERLTPTAIAQLLNNLFEEMLQEVFAC
GGTLDKYIGDCIMAFFGAPEPQADHADRATAAAKGMLIRMEHLNANGFWQ
EPLQLRIAINSGKAVVGDVGSSQRVEYTALGGTINLAARMEAVCPPSECV
ISEATYELLSQRYDFQKMGDYRFKGIDRLVKVYQTKLQHVTTIINH
>Ava_B0202 Serine/Threonine protein kinase
MCSGFPDNQKYLQSLEENSNSELKESNTLLNDRYRILKPLGQGGFGKTFL
AIDEKSTQNSQDEFDYSPSNICVIKQFLPQLQTSHHSQKALELFQQESLL
LAELGKHPQIPQLLNTFEQDGQHYLVQEWVDGLNLKQELAEAGTFDEAEI
IHLLRELLSLLQFIHSYQVVHRDIKPANIIRRRTDRQLFLVDFGVAKYNW
HLVTGTIIGSAEYAAPEQIRGKAVFASDLYSLGVTCLHLLTKVSPFDLYD
CSENNWIWDSYLVEPISPSLEKIICKLVQPATKLRYHFAAEALIDLNNLP
KDFGGSSNLSTNTNNEDFETPYFGLRREADLIGSVTSFADSSVGSVTIFD
PKTKTWHYIPAKTEGGELARKVAAFLAPRLAAATPTVQEEKSIAVDQKAR
NKLNKMYQIIVTAIAFTIACLALAVESNSISTNLKAEISRTIQQFMNIGH
NETPQH
>Ava_1086 Multi-sensor Hybrid Histidine Kinase
MAALMRSRDWSQTSLGAVETWSQSLKTAVRIMLTCRQAMFVWWGNNLINL
YNDAYRAILGGKHPEALGQRAAVVWQEIWDQVGPRAETALFQNQGTYDEA
LLLIMERNGYPEETYYTFSYSPVPNDDGGIGGIICANTEDTSRIIGERQL
ALLKDLAAKTADAQTFDEACIFSTKCLATNPYDLPFAMIYLVDPKQQCVT
LAGTCGIERGHQAVPETVALEENSFWRFAEVLTTHKPYLISDLQLQFPDL
PTGAWNRPPHQAAVVPIAPSGRMGKAGVLVAALNPFRLFDDNYQGFLNLV
SAQIAASIGNAQAYEEERKRAEKLAELDRAKTTFFSNVSHEFRTPLTLML
SPLEELLTADDLSQEQRQEMTLIHRNGLRLLKLVNTLLDFSRIEAGRVQA
VYEPTDLSTFTAELASIFRSAIEQAGLQFSVTCEPLPELVYVDRQMWEKI
ILNLLSNAFKFTFSGAIALTLRQVQHQVEITVTDTGIGIPQAELPHLFER
FHRVEGARGRTQEGSGIGLALVQELVRLHGGQVQVDSLEGLGTTFTITVP
MGIAHLPPERIQATRTLVSTALGAAPYIEEALSLLPAIKNSEASYLSPLT
HNLSSSARILLVDDNADMREYVKRLLSRHYVVETATDGLAALEALADHLP
DLVLTDVMMPRLDGFGLLSALRSNNRTREIPIILLSARAGEEAKVEGLEA
GADDYLIKPFSARELLARVEATLKLAQLRRDAMEQQQTLRQEAETAKQNV
ETILSSINDGFYVLDRDWRFTYVNDRLCKIISMEREDILNHSIWDLFADT
IGTDIDLQFQRAFNEQTSVQFEYLYVTWNRWYEHRVYPSPDGLTVFAADI
TERKQAELEREQLLALERHYINQLQGLTRAALAINSALSVEQVLQVITDQ
AASIIGSHQSVTSMTIGQNWSQAISAIFLSDKYTQWQNYDVKPDRSGIYG
CVGHLNRPMRMTQAELEAHPQWRGFGKEAKNHPPLRGWLAAPLVGRNGQN
IGLIQLSDKYDGEFTAADEAVLVQLAQMASVSVENVRLYEAEKQARSAAE
ASREEAEAANRIKDEFLAVLSHELRSPLNPILGWSRLLQNGKLDEAKAKQ
AVNIIERNAKLQVELIEDLLDISRILQGKLSLTSSPINLASVIKGAIETV
RLAAEANSIRIEVNLDGEIGLVSGDSTRLQQVMWNLLSNAVKFTPTGGLV
EIRLEQVGNQAQISVSDTGKGISPDFIPYVFDYFRQADSATTRKFGGLGL
GLAIVRHLVELHGGTIHAESQGEGMGATFTLKLPLLPTQLTVNPDSPLLE
LSLGLHGIQVLVVDDDTDTREFVAFLLEQAGARVITAVSALEALQVFTQS
PPDILLSDIGMPDMDGYMLMRQIRALPPDQGGKIPAIALTAYAGEIDEKR
ALKVGFQRHISKPVDPDNLIRAIVNLIDIKI
>Ava_3853 Response regulator receiver domain protein (CheY)
MSVETEEKHKTIFLVEDNKADIRLIQEAFKNSQLPHEVVTVRDGMDAMAY
LRREGEYTHAPRPDLILLDLNLPRKDGREVLAEIKADPVLKRIPVVVLTT
SRNEDDIFHSYDLHVNCYITKSRNLTQLFQIVKGIEEFWLSTVTLPPE
>Ava_1149 Histidine Kinase
MNDSLHKDLSVYQLALGVEAPSQTVTLSPATLLSLVRAQIDLLIEQQLSA
TLWIKLPPGKVWSTEIVRYQSSVDNSGRIYNCQVGESKSEVGEENLTSLS
CSYEHYFDVPLLPNNHLQREYFLVVLSTKFCSLIAAYRPRQNHKIGPLGK
TQNNKSQPLLTITSLEHQVIQRVLDGIKQEVTSELKPIAPSDFICSTACE
PALISQMLTKQLQRQNEINRRISVERIAKLQQHNQKLQTKEQLKDEYLTN
VCQELRTPLTQMKTALSLLNSPTLKPHQRQRYLQMLNTQCDRQSVLIAGL
MTLVELEHNLETTTLELVKLADIVPGVVSTYQPVAQEKGIMLGYTIPTDL
PSVLCVNGGLRQIVINLLHNSLKFTANGGRVWVRARVQGEYVILEIRDTG
IGIAESEIPKIFDCFYRVRSGLIDETNGAGLGLTIVQRLLWHCGGSVNVR
SKVDEGTMVIVQMKIGSTSPT
>Ava_4753 Multi-sensor Hybrid Histidine Kinase
MNQSLVRVLLVDDGESDYILTCNWFSEFRVANCELEWVDNYEAAKVAIAN
NQHDIYLVDYRLGSRSGLELLREAIADGCTSPIILLTGQGDAEIDIEAMK
AGAVDYLEKNQLNAPLLERSILYAIERKQIEKKIREQAALLDIANDAIFV
QDLDGNVLFWNEAAARLYGWQKAEAINNKIQNLWQEKNLALLQKSLNELQ
QKGSWKGELYQTTKSGREIIVESRWTLVHEFGNKSQCILVVNTEITQKKQ
LEAQFLRAQRLESIGTLASGIAHDLNNVLAPILMTAQLLESQIKDERSQR
LLPILITNAKRGANLVKQVLSFTRGLEGERTLLQLKHLVGEIQQIIKETF
PKSIELAAHISQNLWTVSGDATQLHQVLMNLCVNARDAMPKGGTLKITAE
NFLIDENYARMNIDAKVGPYVVVTVTDTGIGISSDILDRIFEPFFTTKEL
GKGTGLGLSTVLGIIKSHGGFINVYTEEGEGSQFKVYLPAQDTKELLEEA
ALELSPGNGELILVVDDEAAIRDITKTSLESYNYKAITASDGIEAIALYA
ERQDEISLVLTDMVMPSMDGLTTIRTLQKINPLVKIIAVSGLAAHDKVNA
AYNMGIQAFLSKPYTANQLLKTINAVQHKN
>Ava_0507 CheW protein
MVSKPDFLNGGGQDHFRPELQVESPEGELHLRFYIPSHQEFALPATGIRE
VMELSPDRITPIPNASPLLLGTLNLRGRVIWVADLGQFLGEATPLNTDRA
EIPVIAVQEQDTTVGLAVDAIGGMDWLDVQNLMPPTSIPDTMAPFLRGEW
LLEPKNNQSLRLLDQMAILRSARWAG
>Ava_4701 Multi-sensor Hybrid Histidine Kinase
MFNCTTSLTQSELKSAIIRDPLIIKPETTVMDAIAQMSAVRAICDTDKLD
EVHLEARSSCVLIVEAGRLLGIFTERDVVRLCSQRRCLENLAIREVMIHP
VVSLHESEFTDLFFAVNLLQQYRIRHIPILDEEERVVGLLTNESLRQTSR
SVDLLRLRLVSEVMTCEVICAAPDSSMLAIAQLLTENRVSSVMIVQLCEC
PANPQKIPVGIVTERDIVQFQALGLNLETCQVQTVMSTPIFAVRPDYSLR
FVQQIMEQRLIRRLAVTGEQGELLGIVTQSSLLQALNPLEVYKLAQMLEE
RVVRLETEKVQLLENRTVELEQQVADRTASLKAKAGREQILSDISRQIRS
SLSLQTILDTTVEQVRQLLGCDRVNIWHFEAEWESIVMAESTTSSRSLLG
KRIQEICFQQRCAELYRYGRIRIVPDIYTTEMTDCHRELLIRLQTRAKIL
VPLLCGDELWGLLNVTESQHAREWQTEEIELLQGLSVHLAIAIQQATTHQ
KLQEQLIALQEGSDRLQESEQRYIALNQNLEAKVEERTAELQAREAQLQK
ISERLALSLKSAAIGCWDWDIGENTIFWDERMYELYGVTKTTDSRLVYDT
WANGLHPDDRTNTEILVQQAVLGQAEYDTEFRVIHPDGSIHFIKAYGVVV
RDAEGNPQKMIGVHFDISDRKKAEEIIRQQAEREKLLREITQRIRQSLDL
QTIFDIACQDIRQVIQADRVGIFKFYPESNFNDGEFVAESVVDEFPSVIA
IRVHDQCFGENYSSLYALGRSYVVDDIYNSDMTTCHTDILAQFHVRANVI
MPLLCGAELWGLLCIHQCATTRHWEQSEIDFTQQLATQLAIAIQQASLVE
QLQQELAERQQAELKLTQSNQQLAISNQELARATRLKDEFLANMSHELRT
PLNAILGMTEGLQEGVFGMINDKQFKALETIERSSSHLLDLINDILDVAK
IEAGQIKLDCTAISVAALCQSSLVFIKQQALQKRIQVEIKIPLNLPDLFV
DERRIRQVLINLLNNAVKFTPETGRISLEVTQVSPDISTVQNFLQIAVID
TGIGIMQENINKLFQPFIQIDSALNRQYEGTGLGLALVKKIVELHGGRVG
LTSELGVGSCFTIELPCTPSTPSSPELIRDLLTTPNSELDFANAEEAASL
APVILLAEDNEANIKTFSSYLSAKGYGILLATNGEQALELATIHQPDLIL
MDIQMPGIDGLEAIRQIRLDPELVNIPIVALTALAMTGDRDRCLQAGAND
YLTKPVKLKQLATTIQQLLMETKK
>Ava_0061 chemotaxis sensory transducer
MINKTDMAKSDDAQNQSSLISPTQAGNGIGRISNKLSHLVNQQNLGVYYQ
RLSLKTKAVVLAIALGTLPILTVGAIAYNLLNKSIIQQTSQAQQTAATKL
TDTVNRFMLGRYADIQFISRLPFLANPQVSSKTSKEEKQLVLDSIIEIYQ
NYESIAVFDIQGDVIAQSTGEILYNQKGQSYFQETLRKEAPLIQQSEPSS
IDITAPIKDITTDQIIAVVRAKMPIKSLEAVIKDYAVNGNTYNLLDTSGI
IFLSPEKELLGKEAKANYPDLAARLDGKKVASFLTTPKVNKKPVLLSYVP
PQNLAGLPDLNWQVLLTTDADALLLPQRQLLWTILLGTAFAACAVGAIAA
WLANRTIQPLSQATTTLAKLGQGEFPSRIEVDREDELGVLATNINQVAEH
LQIAVKQKGFVVTNPDQEWQPQDVLQLQLLELLSNVEGVAKGDLTVRADV
TAGEIGTVADFFNSIVENLRDIVTQVKQAAGQLNTAIGSNEGAIRQLAEE
ALTQATEINRTLDAVDKMTHSMQAVADSAQQAATVANHAAFTAAKSGQAM
DLTVQNILSLRTTVGETAKKVKRLGESSQQISRVVSIINQIATQTNLLAI
NAGIEAARAGEEGEGFGVVAEEIGELAARSAIATQEIEQIVENIQRETSE
VVKAMEVGTTQVVEGTRIVEEAKQSLGQILDVSRQIDSLIQSISTATVSQ
VETSQTVNRLMQDIASVSQRSSDSSRLVAQSLKQTVEISHQLQKTVGTFK
VS
>Ava_3776 Response regulator receiver domain protein (CheY)
MNTVLVIEDGLTDREILIRYLQQAGYSVISATSSEEAQEKLDVTQPDLIF
LDVILPGKSGFEICRELKNNPKTSNIPVVFCSTKNSDVDKTWGNMLGAEA
YLSKPINQEELTLTLKRLSR
>Ava_1255 Predicted sensor protein
MLEGSILQQLEASHRHSTRPVRFGVYYKNTLVALCHALEDHILADDNSPL
VITAFQRGKWYLQEAERYADIAQCSRQIAIMAAPDAGFAEHPTSQLPNVN
LVPLDPSDPVAQEWHLIILSPKYTAMVLCQELSDADYGVGGRPASDVERK
FYGLWTFEPELVKETAELAIAHIQKYNPELAAKLLIHAQGIENYVSTSED
LSIVVSRVVDYLQTGQEQLSIPAAVRQQALDSNLVSNEIQAFLRMAQLMD
LADITNPQAAAEVATLAETLAQLLDLPAWQIKRLKLAGLLHRIDPLQKAE
SIFTPGTSTHHQESAPSCPLTCSLVPGAQALRKMSRLRAVAQIITHQTEW
WDGTGEPAGLAGDEIPLESRILALVADFQWQVNQKRTASENRQEIFVQAL
EECRQQANRFDPKLIDALFLLVMGLQQGLDLPLMTPKVSTGMWLLDSRWD
SQNKTSEEMSSYPQ
>Ava_4343 Multi-sensor Hybrid Histidine Kinase
MADEIIKVLLVEDNPGDAFLIQELIKEVNTAHLELHPVERLSEALKILAS
DTYDGSLPPFDVMLLDLSLPDSQGIDTFVRANRETNLLPIIVLTGIDDEN
LALTAMQKGAQDYLVKGQVTGDLLVRSIRYAIERQRVEEALRHSEERFRV
ALKNSPIFVFNQDRDLRYTWIYNPIAGWTVEEMLGKQDSEIMSEQDAQCL
TAIKYHVLTTGIGTRQVVSIGTLLGTKYYDLTVEPLRNESQDIVGITCAC
IDISERKLAEAKIREQAALLDITTDGICVRDLENKILFWNKGAENLYGWQ
AHEVISKNASDLLFREPSLEVETALLNVISQGNWQGELNKVTKTGKEIVV
ASRWSLVYDEQGKPKSILSVDTDITQKKHLEAQLFRTQRLESIGTLASGI
AHDLNNILTPILAGAQLLPLKFPDADERTQHLLEILEINAKRGADLVKQV
LSFARGVEGKRITLQLKHLIVEVVKILKETFPKSIEVYTDIPNDLWMVSG
DSTQLHQVLMNLCVNARDAMPNGGTLTISAENLLIDENYARMNLEAKQGH
YIMVTVSDTGVGISPENLDRIFEPFFTTKAVGQGTGLGLSTVLGIVKSHG
GFVNVYSEEGRGTTFKVYLPSVGGMEAPHIDHLLPPAGHGELILIVDDEV
SIQDITKTSLESHQYETLVANDGVEAIALYAKNADKISAVLMDIMLPVLD
GLTTIRTLRKINPQVKIIATSGLISKNKLTEIVNTGANSFLAKPYTVNEL
LLALHEVMI
>Ava_2026 conserved hypothetical protein
MVTFPQENTSRNLMQLKPLSLLVGALALTLTATPFAVQAQTNSSSVLLIA
QAGKKGPWESLGLSNEQKARIQEIGRNSRAQIEAVFTPEQKAKMEAARQA
RQAQRQQGQRPQAGQRGGKKNFAELNLTEDQKTRIRSIRQTSQQQMEAVL
TPEQRTKLQELKANARQRWQQRRNNQPSPQS
>Ava_1565 Putative Anti-Sigma regulatory factor (Ser/Thr protein kinase)
MNHKIYLKLNTDLSASAKVLSWFEQINQPVISHKQIWWQCQTLLMEGFVN
IVEHSHKHLPIETPIEIEVSRTQDYIEIRIWSQGEPFDLEQRLKKTTELE
KNIQERGRGLKIMEAIADDLSYEKLADNRYCLLIRKHY
>Ava_0198 Multi-sensor Hybrid Histidine Kinase
MPSLYPVDLPTIEQVMECYPLTVLPDTLLVDVIALMNPVSRCTIVSASNF
SSCVLVVEEKKLVGIFTLRDVVRLTGVGVDISRKKISEVMTQPVISLTLA
AAQNALTALAFMRQHHIRHLPVVDEQGQLLGLITQDRIRQVVQPAHLLKL
RCVTEVMVTEIIHALPTTSVLELSQMMSDRRISCVVIVAPQETKLIPVGM
ITEKDILKVQLQGLDIAQTPAQTVMSSPVFSISPRESLWTVNLLMQARGV
RRLVVVGEQGQMQGLVTQTNLLQVLDPLEIVNVIQALEAKVAEQTFQLQQ
TNQQLEAEIKQRHQVEESMRQTQKELEFRVAERTAELMQSNARLQQREQQ
LQALFDHAVDAILIADDEGRYVDVNAAACELFGVSRGELLASTIGDFAAL
EFNFTEAWQHFREQKQMSGEFQLHRPNGTVRATEFAAVANFIPHRHLSII
RDVSDRQQAKANLQNSEQRLQLALSASSTGMWDWNLQTNEVVWSESMCSL
FNIDPQTFNNRFESFVNFIHPEDREFVEQHLMQSIDQNTICNVEFRVVWL
DGTVHWASGKGNVFYDEVGKPIRMIGVHQDITERKQAEAKLQKSEQRLKL
ALWAGNTGTWDWNLQTNEVIWSDHLFSLFGLAPDTFDVSYENFLNLIVHP
EDRELLHQSALRAIEQQVPHDIEFRFLYPDGTVGWSLCKGQVLYDDITGE
PLQMIGVNMDITERKNAEEAVRESNQRLQAIIDNCPAVIYVKDMQERYIL
VNSEFERITHLTREQVKNKTNVKIFSPKTARSLSINDQEILSSRTPVQFE
EEIQFEDGLHTYLTVKFPLCDATGEPYAICGVSTDITERKQAQEQIRQQA
ALINVATDAIFVRDLANRILFWSRGAENLYGWTAEETVGKLAHELFHKES
SSQLEAAVTTTLEQGSWYGELEQTTKNAQEIIVASRWTLVHNQFGDSPSI
LVVNTNITEKKQLELQFYRVQRLESIGTLASGIAHDLNNVFAPIVMIAQL
LPSRCKNVDTRTHELFKTLETSSKRGSDLVKQILTFARGTEGQRILLQPG
HLLKELAKVIQQTFPKSIEIITDIPTNTLWMVQADPTQLEQVFMNLAVNA
RDAMPNGGKLTITATNRVIDSTYARMHLESEVGDYIVVTISDTGTGIPPE
ILERIFDPFFTTKEVGKGTGLGLSTVLGIVKNHGGFVEVASQVGQGTEFQ
VFLLRGKGTATETIAKTKLPRGNGELILVVDDETIIQQTAQEALADYNYR
ILVANDGIEAIALYVEYQPEISVVLLDMVMPNIDGLTAIRTLRTINPKVK
IIASSGLPANEQQAIVAGANRFISKPYTTTDLLTTLSDVIGVKE
>Ava_0024 Periplasmic Sensor Signal Transduction Histidine Kinase
MGLSILRTQKILKLFKTEPEQLSWQIMFLLMIFFLGGYLGSIYLIIARLI
EWIPLLTGMVFFFGALFVFFSVTIYYHTLQRLFIVQEKYRAAKENAESAL
FQLKETQQAQMQLIQRETMLALGTMVAGVAHEINNPVSFIHGNLEYLHQY
AHDLLNLLATYASVYPNPDVRIVKALANSDLKYIQSDLPNLLNSMQVGAV
RIKEIVESLSNFSRLNEANYKKANIHEGIDSTLVILQHRLNCDGSNGQPI
SVIKEYGKIPQIFCNPRFLNQVFLNLINNAIDALISKVATLAPNIDETPT
IWIRTFHSQDNQITISIADNGCGMSEEICRSIFQPFFTTKPVGQGTGLGL
SISYQIIVEQHGGSIKCTSIENQGTKIDIVLPIKQLENSN
>Ava_B0099 conserved hypothetical protein
MTDTPSNRLDRIEAILSTVASQQQLNTQAIAQLTTKLDSLSDNVNDLTSN
VNSVLARDAILNDVLLELRDSHEQHQQNFEEHQRTTNAALNQLGAILVQL
TRIDPQN
>Ava_0521 Multi-sensor Signal Transduction Histidine Kinase
MKLGVSFFSISMIRNSYEPPNPSDLPDCHNQLRLTAQYQKILVRILAKIR
SSVNIESLCRTSCQDICGQLQIERLAIYRFNSDWSGSFINRFGFAEPPWD
KLTAFGQDLVWQDSHLQETQGGRYRKNEPFATADIYDAGHSRCHIEVLEQ
FQIRAYAIAPIVVGAKLWGLLAAYQHSAPRQWHQNEVEFIAQAASYLGVA
MQQEEIIKEAKQRTVELQDAIARQRALMEVVGNIRSSINTEIILNTACQE
LCKLLKLERAAVYRFNEDWSGEFVSQFGMVETQWHRISPFGKNLVWDDTY
LQETKGGRYRHNETFAVNDIYEAGHTRCHIDILEQFKIYAYALAPIFIGK
KLWGLIAAYQHTGPREWANYEVEFLGQVGAQLGVAIQQAENLAQSKQQAD
ALQNAIARQRALTEVVGKIRSSLDINLILKTTCQEVCKMLRIERVGVYRF
NPDWSGEFVSNFGMVEAQWDSINPFGQNLVWEDTHLQETKGGRYRNNENF
AVNDIYQVGHSRCHLDILEQFKIRAYALTPIFVGRNLWGLLAAYQHSAPR
QWDIVEVEFLGQVASQLGVALQSSQMMSQIQTRADELQKSAEQRRILFDL
VVKIRESLDLEAILKNTVQEVRRSLQADRVGIFRFDSDQGFCSGEFIAED
VLPKFDSALAVKVQDYCFGDHYAPQYRQGQVQVISDVNSVGSKVPHLDVI
EQFQVKAQIIVPLMEGDNLWGLLCIHQCTHPRHWEEDELEFVTQIAAQLS
VALHQANLFQQSSLLGETRAEANQLAQTLKELRTAQMQIIHAEKMASLGQ
LVAGVAHEINNPINFIHGNLEHAHQYTQELLRYVKLYQHYHPNAAPEIQE
FFQQAEIEFLFEDLPNLFQSMQVGTQRIQEIVTSLRSFSRLDEADFKTAN
IHECIDSTLMILQHRLKPSADSHAIHVTKDYDDLPLIECYPGQLNQVFMN
LLSNAIDALEEREAKLSPEVIAAHPSEIRIYTSLLNQDWMSIRITDNGLG
IDEQIIPRLFDPFFTTKMVGKGTGLGLSISYQIVTDKHKGKIYCQSELGK
GTEFVVELPILQAKINPSITKV
>Ava_3368 Histidine Kinase
MLLLGFFLGLAVGIGLWIWQQIQLNRYLTRVTQPLHSHTSKLKVALPLLP
RLQREIATLKQHRLDLQQSLQTYQDLLEFAPVGYLQVDEENQLLWCNQQA
REILYLQRWQPGQVRLLLELVRSYELDQLIEQTRDRQKPQTKEWVFHPSC
DNAAEMPTIKSMMLRAFSLPLHDEQVGVFLENRQPLLDMNQLRERSFSDL
AHELRTPLTSIRLVAETLQNRLEPPLNRWVDRLMQEVDRLVNLVQSWLEL
TQMEANPTMQLQMETVELRSLITSVWETLEPLAQRQNLSLSYSGPEKLLI
KADSARIYQVFLNLLDNSIKYSSPNTSIQIQAEILSFKKNHEANSAPPIL
EINLIDAGKGFAEEDLPHVFERFYRGDKARTHSALQDTNIVGNGLGLAIV
RQIILAHGGSIKAMNHSEIGGAWIQLHIPEVVAN
>Ava_1343 Multi-sensor Hybrid Histidine Kinase
MGKKFSVIHKLKVLFVLALVVLLTNTVITYSHTTRLMENQPYLYILEHKT
LVAFCLVIFVNILLLTYLYKLLCLYITKSQQAEQKIREQTAILNIVNDAV
LVGSIDHQIIFWNKGAERLYGWKAEETLGKNITEILYQPSSTKLKSALST
VMSEGEWRGELHQLSKDGEEIIVESRWVLVRDEEGQPKSILSVNTEITPK
KQLEAQLLRSQRLESIGTLASGIAHDLNNILTPILMAVQLLQMKLHEPQV
QKVLNTLESNVKRGANLLRQVLSFARGIEGKKTIVPVRKLILEIEQIVQQ
TFSKSIICQTYIPENLWYVSGDTTQLHQVLMNLVLNARDAMPNGGILKIT
ADNVVLSPQGKHYIKLSIEDTGLGIPAKIQKQIFEPFFSTKEVGKGTGLG
LSTVLNIIDNHGGSINVQSTEGKGTRFQVYLPALVSNMEIPLADSVEMES
PTGNRELILVVDDEAIIREITKSSLEAYNYRVLTASDGEEAISIYTGYQE
QISVVLLDMMMPSMDGAIAIRKLQKINPQIKIIAISGLLSEPHESAIANM
GVKAFLSKPCTAKELVQTIHTVHTEN
>Ava_4681 Serine/Threonine protein kinase
MVWNPGRHLFGSRYIIERKLGEGGIGITYLAKNPQGKLRVIKTLREEILN
HPTWIPHQSRLKQDFKEEALRLALCRHPHIVEVENVFDDGDLPCMAMEYI
EGEDLGKRITEKGALPEAEALQYIRQIGDALMLVHDKGLLHRDLKPSNIM
MRAGKPGQKQC
>Ava_3283 Transcriptional Regulator, Crp/Fnr family
MIVTQDKALANVFRQMATGAFPPVVETFERNKTIFFPGDPAERVYFLLKG
AVKLSRVYEAGEEITVALLRENSVFGVLSLLTGNKSDRFYHAVAFTPVEL
LSAPIEQVEQALKENPELSMLMLRGLSSRILQTEMMIETLAHRDMGSRLV
SFLLILCRDFGVPCADGITIDLKLSHQAIAEAIGSTRVTVTRLLGDLREK
KMISIHKKKITVHKPVTLSRQFT
>Ava_3072 Two Component Transcriptional Regulator, LuxR family
MIGVMVVAASHVIRAGLSAVIAGNPQMTVVGSVSDIDGMTKEIQQLQLDV
VLLDWGRNSQSDWDKLLVIQEQQDSLRVMLIVKELEGIDIEAALRSGVRG
ILLDTSTESEILTAIEAIALGLIVIHPDVLEFFSVREKAVTNPVQSLTPR
EIEVLQMLGSGLGNKAIAQSLHISDHTVKFHVSSIFQKLAVSTRTEAVTV
GVRLGLILL
>Ava_4086 Histidine Kinase
MMVVMGLSSVVVYHFFAYSLSQQLDRQLLTLADAAAHNLSAIKVDKMAVN
RKMPRILDNDGDLDIPWQDLRLYRQSVEWFDAGQQLLGKAGKPFPETPFL
TNFHSWQQNGIRILTIPVYSSRKNQQLLGYVRVSASTVEIQKELERLLMG
LGIGGVLGMVLISGTGWWLTSKALQPIEQSFQQLQQFTADASHELRSPLT
AIKTTVEVIQSHPERIHPSDVKKIDIIEGATQQMTHLVEDLLLLARSDSA
PISLPKTAIPIPIDEILIDLIDTLQPQAKSQEITLEANLIDAVWVKGDAH
QLQRLFGNLLENALQYTSNGGLVRVEIVKRDDFVVIEVADTGIGIAPENL
PFVFNRFWRAEKARSRRQGGSGLGLAIAQAITHAHGGEISVTSKVGVGSC
FRVKLPVFRLGN
>Ava_4695 UspA
MYQKILVAVENSEIGQHIFEQGVNLAKVSNAEIMLLHVISPVEDPYITPI
FLQPDTTYPAWQTESMDNYIQHWEKLKQEKLEWLRSLTDTAINIGVKTGF
TQKMGDPGRTICEIARSWSADLIMVGRRGRAGLSEFLLGSVSNYVLHHAH
GSVLVIQGKTLS
>Ava_0799 Histidine Kinase
MCDNREEEIEFLQRADETAIHLLGIINELLDISKIEAGKLSVVSQPLDLR
QTLLEVINLQSVNVQQKGLQLKTNLGTEPIPVKADAAKLKQVLINIIGNA
TKFTDEGGISIATTIQTRIDGKSQVMVSITDTGLGIEPAQQHKLFRPFVM
VNGSTTRKFEGTGLGLAISRNLIELMGGTITLESAGINQGTTVNITLPLI
DISLLGLSATDNNKNQKNSEGDEEIKGTDSFSSNHPEAIPLDCNENYGSK
KTELEEYTDLERVNLFVIHNS
>Ava_4457 GAF Sensor Signal Transduction Histidine Kinase
MKKRLLLPPQYPDGPERLQPYPVKLMQHQEETAQELAHKINHIVASRPAT
AAMLQEIAHLVGTVTNVDCCCLVTVTNEESTETTTANWCSDEFLGVPLSN
EMFSTERFLMELPVLQCAVEPRNIDEISIIRNSLVVGCQHLPLPIKAVLA
ISTRFGGKTNGVISLIKFQSHDWDDSAKKILKTIEASCAIAFSQLTQAQL
ISSQQQHLQKSNQHQSLIKQLTILSRSNLELNQMLQLAIASTAECLQADR
GLLILLKYTDPLFRTPIKKQIPQAKADVVGEWRKENANQTDSLPGSFSLA
DCGLCQRVFQDAGKPVIINDYSELQDTSTVAPLFAITELPAVLLMPLENQ
GKILGFLVLQQGVARNWQQSELNLVEMVCAQVSNAIIQSKTLRQVQTLVD
ERTAKLQSSLELQAKLHERTRQYVEQLRELNQLKDEFMSNISDRLRYPLT
NMMMSIKNLRLPGIPPERQVKYLEILENECAKEINLINDLLTLQKLESEQ
EPPRVENINLNAKIQDLSDSLASKLAGKGLSIDLDIPDEPLKLQTELESF
DRILHELLNNAYTYSERDTIVHLHASHQVDQLVDQVMIKVTNTGRGISEQ
EATYIFDRFRRGRGGRWTPGTGLGLALVKSLVQHLNGAIAVESNPIPGSQ
LSEICFTLTLPQFSDESTPYSESD
>Ava_0162 phage shock protein A, PspA
MRFLACLLTVLARFCKILNFVGASFAVGYAGVSLLGLIGKSEWRAEMELI
KRIQRVISANFNSVVASKEDPEKILEQAVMEMQENLLRLRQGVAQAIATQ
KRTERQAASAQSTAEEWYRRAQLALQQGNELLAREALTKRQSYVDAAKTF
SSQIGEQIEIVDRLKKDMRSLELKIAEAKTKKDMYIARARSAEASYKLQE
MLSGGSATSSLNAFERMEEKVLQIEAKSELITQMGSDDLQKQFDSLEAAN
DVDSQLAAMKTQALSEGENTPQQQLPQGENY
>Ava_2323 Protein tyrosine phosphatase
MPYKLLFVCLGNICRSPSAENIMNHLIEQAGLSNSIICDSAGTSSYHIGS
SPDRRMSAAAVTKLGIKLRGQARQFVKSDFQEFDLILAMDRDNYDNIIAL
DHTGQYHNKVSLMCEFCSRHNLKEVPDPYYGGTEGFNQVIDLLVDACEGL
LQHITSQ
>Ava_3780 Protein tyrosine phosphatase
MNKILFLCTGNYYRSRFAEHLFNQLATKQGLNWQADSRGLALERGVNNVG
AISQYATEALAARLVNISDDERFPKPACEPDFQSATRVIALDEAEHRPLM
NERFPQWVDAIEYWLVHDIDKTSATEALGQIEKHLLQLIEQLTQS
>Ava_4779 Multi-sensor Hybrid Histidine Kinase
MFNRLKIGSKIGAGFTISITILSTIGFVSYQSIQELIVASHKERHTYQVL
RQIADLNGLLSTAESGQRGYIITGEIRYLEPYQKATKSLDIRIKELQKLT
SDNPQQHGYISRLEPLINERISVMQTVLDLRQNQGFEAAQKSILSDRGRA
IMAQIRSISQQMNAEELKLLEQRTAMAQNAANNTLATITYSIPLVSFILA
LIGYLLTRHISFPLQQISHAAERMSSGDLAVTLPNSIRQDEIGILTRTFN
QMVANLRITTQKNEEQNWLKSNLAEFTQLLQGQRNLESVSSLILSKLTPL
VESQQSVFYVIDRNHDEIILKLTGSYAYNERRHLANLVRLGEGLVGQCAL
EKQRILLTEVPSDYIRISSGLGAALPLNIIVLPVLFETEVIAVIEIASFR
RFSELHLTFIDQFSEVIGVFLNSIYASAQTQNLLDESVALAAELKQSNQL
LEQQTQDLENSELLLKQQQQELQQSNEELQQLNEELEEKAELLEIQNSEV
ARKNQEIEKARKFIEEKAEQLALSSKYKSEFLANMSHELRTPLNSLLILA
KLLADNSSGNLSNKQVEYSQTIYSAGTDLLELINDILDLAKIESGTLSVE
LEPIDFADLHDYIERTFRQVAQDKGLSFSIELDERLPSTIFSDPKRLQQI
LKNLLANALKFTEEGGVTLRIGLDQINTNHPMITFAISDTGIGIPQEKQQ
IIFEAFQQVDGTTSRKYGGTGLGLSISRELTQMLGGRLGLVSQPGQGSIF
TLYLPQTYPENKTKVISQQQTSSPPHQLPPVSPENLQPIALTNTIADDRG
IIQPGDRLLLIIDDDDKFARILLDMARQQGFKAIVSLNSKQGLALAQQYQ
PNAITLDIYMPDMDGWTLLDRLKHDPQTRHIPVHILSVDDREQRALQLGA
ITFLQKPVSPEILNHTLTEIKSFIDRKVKRLLVIEDDPVQAQSIIELIGN
GDVQSMAVNTGAAALEILRSQHFDCIVLDLGLPDMSGLELLEQIKQEPNL
VKLPIIVYTGKEISRQEETQLRRLAESIIIKNVRSPERLLDETSLFLHRV
QANLPQPQRQILEQLHQTDPILANRKILIIDDDLRNIFAITSLLESYQMQ
VLFAENGRDGIELLQANSDINAVLMDVMMPEMDGYETTRSIRQQKQFRTL
PIIALTAKAMPGDREKCIEAGASDYITKPVDTEQLLSLLRVWLYR
>Ava_4391 Serine/Threonine protein kinase
MLAGKILQGGKYTLIQEVGRGGFGITFKATHHYLGHEVVMKTINERLRQH
PDFAKFERQFQDEARRLATCIHPNIVRVSDFFVEDGLPYMVMEYIPGETL
GDAFVLPAIPLPEETAIHYIRQIGAALQVVHNNGLLHRDVKPDNIILRQG
TQEVVLIDFGIAREFNSGVRQTHTGLVSEGYAPIEQYLTQAPRTPATDVY
GLAATLYALLTGQVPLPALLRDREQMPAPRELQPHLSAAVNQAVMRGMAV
ESRFRPPSVTEWLQLLPGSGINLPIHALPTHAVPTIDLSVHLQEKFSGAK
TSGSVKKPSPLKNIALMAQKSGTSQLFLGVIIALVAAAAGFSATSLFSRS
WTQPSAKPLFEERPMVPVGGKSQVDSPQKQDNTRQNSQNYSASETTPVST
SRRRRRNLTNQQTESPNPNSNSPEQSPQLNTGELQPRNYEQPGLSPNTSS
TPSLVEKLREIRSSRTAKPANTTDTSPPSSTQNSTTPVEPPSNSIVVPVQ
PTEPKNSDSSVVVPTVEVKQNSSTESQIPAPSQKNEKFPENTQINN
>Ava_3721 Histidine Kinase
MLTPLSKKTAISLPNQPLQQENINLKLIVEGIASQVGEAFFQACAHYLAE
VLQIQYALIAEFIDDEQPRARVLAFWKGEEFGPNFEYDLAGTPCGVLYQE
GLQIYPDCIQKKFPDDLDLVNLNAESYLGVPILDPQGKPLGHIAGLHIKP
LERSYEEQEAILKIFAARSAAEIERQLAEKALKQQNIHLEQTLKELHKTQ
IQLIQAERMSSLGHLVAGIAHEINNPIGFIYSNITHTREFINILLELIVA
YQLEYPNPSISLQQKIKEADIEFLQKDVAKMLKSMETGSDRIRDIVLSLR
NFSRLDESSKKSIDLHEGIESTLLILQHRLQANELLPQIQIIKKYQPLPK
VNCHASQINQVFMNILSNAIDALQSASNTITQPRIEIKTEVIFPENTVRI
SISDNGIGIDEISISHIFDPFFTTKPVGSGTGLGLSIAYQIVVEQHRGKL
NCISTPGQDTKFEIEIPM
>Ava_B0017 conserved hypothetical protein
MKPIMKKLTISAIAATTFGSLFIAAPSYGISINDFFSSIVSDFQTEISKI
QDDAKEKINISWAGIKTDAIAAIDSSIGQLGAPDPIASADQLKDSLKDDY
SYPVAQQNAQQLERQLTLASVSSIVSKDGQQQTQEKIDTTAQIAQQAKSI
ADEAQNMDASQNVLKAIAAQNGLIVSMLAEQRTDSLSARQDNAYSNLMLT
QVAEHLDSERKKENSQEDGRLSLVHEIVLNARLDPASAD
>Ava_3851 Two Component Transcriptional Regulator, LuxR family
MASNPVKILLVEDDELFRLGLRVRLQQEAGLEIIAEAEDGETALDLIKQN
SLDVVLLDVGLPGLGGIEACKQIKQQNPQLPILVLTSHSQKPLISKLIEA
GAQGYCLKGIIAEKLVLALRSVAAGASWWDETATREIRSSIESSQSQSPE
QNFTKSDHPLTGRELEILSLLAKGKTNQEIATALYITPGTVRVHVHAILH
KLEVSDRHQAVVVALQKRLIQNSAIAD
>Ava_3453 Two component Transcriptional regulator, Winged helix family
MNVLFVEDEAKIANFVQAGLKEQGFVVDYCDNGDEGYLRALDNEYDAIIL
DIMVPGKDGLSILKQLRQKGRNAPVILLTARNELDDRLAGLNLGADDYIA
KPFFVEELVARIHAVVRRSIGDRQNLLVIGTLKLDRITREVTCNQRVIEL
TSREFNLLEYLMRSPGRVFTRTQILEHVWGYDFNPNTNVVDVCIQRIRKK
IDPVDEAGWIESIRGVGYRFRHPI
>Ava_4550 Cyclic nucleotide-binding domain (cNMP-BD) protein
MQASLEQLSQIMVFVGIETSDKESLQPYTQVQGYKKGEIILHEGDRLPAK
LYAVVSGSIQVTKTATTGKETILRGLNAGEIFAAPALLGDSIAPATVTAE
SDCEILTVQRDALLQAIQSNPEIALRMLMVFNTRIQQLHETVHGLVSERA
IVRLARLIEYFATESGTEPSPQGQILKIKLSYYRMARSIGITYEECVRLI
KTLKSVVAYSRGGKIIILDVEKLNAIACGQSETITCGT
>Ava_0509 Response regulator receiver domain protein (CheY)
MQGSLHEIDIRSILQLIELGQRTGQLLIEAPSLYKPHQNAKEDAEEPDYF
RNYQQQYWLIYFLNGQIIYCQEGDINFSRIDGYLRYYRVEMGLDEQYLTS
LGKLNSSEYEYLWLLLERNIINSQIAENIIYRLVGETLFDLLSLHQGRFM
FCQDTAIAPRLSTWEISPLVTQATQQLQQWHELYPYIQSPEQLPILADRV
HLNSSLPEATMNKLQQWADGKTTLRQLARYLNRDILTVAKVIYPYVQQGW
LKLTHPEANNCPINIHTPGNQKKAKILCIDDTKSICETVESILQTRGYEA
TGYTIPEVIVLTNPLEALGLIFQLRPNLVFCDISSPELNGYEICAMLRQS
QVFRYIPMIMLSSKDKFIDQIRARMAGATDYLIKPFNDDELLMLVEKYLK
SSPTKGWEFGNG
>Ava_4425 Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with GAF sensor and FHA domain
MPGNEWEKIRHILVVQDLQGQRTIPLQEATYSIGRHTSNAIVLHSRSVSR
QHAILLRVTLPETDQCSFRIIDGNFKGQGSTNGLLVNGTRCFSHNLRHGD
VINFGSHQAQAKYYAISNISEKAFFASADVEDLSTFLSELSQPVNPFQTL
VVDPEFEGASETALARLASFPELIPNPIIETDLEGRVTYINPAASVKFPD
LRELGKRHPILKDILNVAENPKINPFVREVTVGHAVYEQSVHNLPESDLI
RTYIIRDITEQKQAEAELHQRDRLLQAVAEAANWLVVEMNYDTAIEKALA
VVGEAAQADRAYLFKNHPHPVTGKTAVSLQFEWYCSGLQPSIQYWQNQLY
QSAELSRWYSILSSGKSINELRRKLPIVERELLERQGIQSLLLVPLRLED
QFWGYLGLADCTQERYWSRHEESTLLTMAASISGAWQRQQVEEKIRYQAL
HDLLTGLPNRLLFNELLAKALANASRSQQSLAVMFLDLDRFKVINDTLGH
SLGDRLLKSVAQRLCDCLRSGDTVSRWGGDEFTILLPHISYIEEVTQAAY
RILKALEEVFHLDGHELYVSASLGIALLDHHSPDAEALIKHADAALYHAK
DEGRNNYQFYTTSLSGKTPELLTLEKSLRYALEKQELTVYYQPRVNILTG
QITGMEALLRWQHPEMGIVAPSIFIPIAEETGLIIPIGEWVLRTACMQNR
AWQEAGLPPLQMAVNLSPKQFRQPNLLEIVSAILAETSLAPEFLELEITE
STAIEDIDFTRSVLENLQQMGVDIAIDDFGTGHSSLSRLQLLPLHNLKID
GSFIKALTTDSKVAHIVKAIVTLGRSLGLRLTAEGVEKQEELDFLKSINC
QDVQGFLFYKPLSAEKATEILQSERKHAAL
>Ava_0679 Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains)
MQLNQKLYLYSTLDNFRLLNKNYTAKIMLVAFLGTHIPLLTLLFSFVISN
SYSWEMTIRVLVIALFATLIGTVVTLYALHHLLIPVNLTSATLRDYLNNK
TLPNLPTEFVDEAGTLMADTSQTLHKLDELIDYISNYDKLTGLPNRELLR
ERVNQALSQQYSQKMVAVMVLGIDDFTGISHALEHEQSNLLLRAVGQRLT
SCLAQKDILAHLSGDEFAIARVEIPSIESIVKLSQLLLSALNKPFTIKGD
QIHITASIGITINQPDNLHDVDQLLQQAHVALYQAKQQGRSQHQFYSPEI
NAQLQERLALENELHGALQRNEIVVYYQPIIDLQTQQITAVEALVRWQHP
TRGLVSPAKFIPIAEANGLIVEIGEWVLRTACLQNRAWQLAGLPPIRMSV
NLSARQFEESNLVELVGEIIQESGLHPSYLELEVTESSLMADIQRSVTIL
KQLRELGVWLALDDFGTGYSSLNYLKRFPVNMLKIDRSFVQDVCSNPDSA
AVTNAIIALAKSLQLKITAEGIETQQQLSYLQKRGCQEGQGYYFGIPAPA
NEITEILQPEEAKEAMLYDRPGVIAV
>Ava_0661 Two Component Transcriptional Regulator, LuxR family
MNKIRIALIEDHDLTRVGIRTALLQKEEIEVVGEAGNATEGLNMLKKVQP
DIAIIDIGLPDKDGIELTKELKSISNGADLPTKVLILTLRDNKEAVLAAF
AAGADSYCMKDIRFDNLLEAVRVTYNGNAWIDPAIARIVLQQAQQQSPKP
VTTITEAKNSFINSETEDNLETIDSYTLTERELEVLQLIVEGCSNAVIAE
RLYITVGTVKTHVRNILNKLCADDRTQAAVRALRSGLVG
>Ava_3775 Response regulator receiver domain protein (CheY)
MVSNNVLNEFKTCTQLQYNGQLIINSPKGQQWTFYYRLGRIVWATGGTHP
FRRWRRLMAQHCPQIDVDKMQLRPQDISMSYWDYRLLEILYKKQKIQREQ
IHNIVDNTINELLFELAQQSNFVSISCERNQKVILETPMSFTSADVSMKQ
MLESWKNWSEAGLVNICPDLAPVICRPEQLQQQVSPSVYKNFVTLINGKS
TLRDLAAKMKQNVLPVSRSLLPYVLKGIIELVELPDLPLAVVETLNKATS
AQPTKSKVPVIACVDDSPQVCKLLEDIITANGMKFIKIQDAVQALPLLIQ
EKPDLIFLDLIMPVASGYEICTQLRRIPTFANTPVIILTGNDGLLDRVRA
KVVGSTDFLTKPVAADRVMSVVRKYLPMQTTSPAKTGSHLEFCQ
>Ava_B0190 Osmosensitive K+ channel Signal Transduction Histidine Kinase, sensor domain
MSNSSTISPDISYIRPYRRGKHKIFIGMAPGVGKTYRMLEEAHQLKQDGI
DVVIGILETHGRKETAQKSIGLEVIKRKVSIRENVTLEEMDTDAILQRSP
QLVLIDELAHTNVPGSQREKRYQDVEVILAAGIDVYSTVNIQHLESLNDL
VARITGVVVRERIPDRLLDEADAVVVIDVTPETLEERLREGKIYASEKIE
QSLKNFFQRRNLIALRELALREVADTVEEEANTSTLEGQNCNVHERVLVC
VSTYPNSVQLLRRGARIANYMNARLYTIFVANPERFLTKKESLHIDTCEK
LCKEFGGEFLHIKSHNIAQEIAQVAARYHITQIVIGESQQPRWKRWFKGS
FTQRLVDLIRHQNIDLHIIATEK
>Ava_2855 Response regulator receiver domain protein (CheY)
MKTVLIVEDDLINARVFSKILTKRGGLGVKHTENVDEVMKIAQLGEADLI
LMDVSLSRSVYQGKSVDGIKITQMLKSDPQTANLPVILVTAHAMEGDREN
FLRLSGADGYISKPVVDHQQFVDQIIALLPSDNH
>Ava_3778 chemotaxis sensory transducer, Phytochrome sensor
MTIAKYNSKENEKVATASQLENPNLANNVQKEEIGVNESAQQVKMWRQQL
QDIIMQMRQVSEWDAVLKITVVKVREKIACDRALIYQFTSPESGKVLAES
RTLGWTPTMGEFLPGITFGLDTNQDYIEPITINNVTQIQLTPYQKQLLDK
FQIKASLSLPIVADGKVWGLLVVTGCVNPRNWQETEITLLTQVSTELTYR
LQNFEFQTQLQLQNQAKQAVSKVMEKILRLSNTDKIFQSTTQEIRQLLKC
DRVAVYRFNPDWSGEFVAESVGSGWVKLVGPDIKTVWEDTHLQETQGGRY
RHQESFVVNDIYQAGHFSCHLEILEQFEIKAYIIVPVFAAEKLWGLLAAY
QNSGTREWLEWESSFLAQVGLQFGIAISHAEYLEQTRLHSEQMMQIAEQE
KIFSRIVNRIRQASDVETIFRTTTQDVRQSLRCDRVAVYRFNSDWGGEFV
AESVASGWTKVVGPNIKTVIDDTYLQDTKGGRYTRGEHHIVNNIYTAGFA
PCHIETLEQFEARAYIIVPIFFGDKLWGLLAAYQNSSSREWQSWEVNFLT
QIALQFSLAKSQLDYLEQVQIKSEKIAQIAEQEKSFTKIVNRIRQAVDID
DIFKITTQEVRQLLRSDRVAVYRFNPNWGGEFVAESVGNNWVKLVGNDIK
TVWEDTYIQETQGGRYAKGETFVVNDISQAGHSPCHLEILEQFEVKAYVI
VPVFCNEQLWGLLAAYQNSGLRDWEQSEVSLLARVGDQLGLALQQTEYLQ
QLQAKSAQLAEAAAREKAAKELLQQRSIQLLMAVRPALNGDLTVRAPITE
DELGTIADAYNNTLQALRQIVLQVQTSSQQVAQTSSDSNASLAGLNNLAK
QQSIEITTALGEIQQMLDSTQAVVTSAELVQVAVQQANKTVESGDAAMNL
TVQAIQGIRETVAQTSKKIKRLSESSQKISKVVNLISSFATQTNVLALNA
AIEATRAGEYGKGFAVVADEVRSLSRQSAAATIEIEKLVQEIQAETGEVA
VAMETGIQQVVEGTNFVSETRHNLNAIVSATAEISQLIQQITDATQKQMG
QSVLVTNSMKDVAEIAKKTFAESQDIATVFQDLSGMAQDLLTTASKFKVN
>Ava_0763 Small GTP-binding protein domain
MTLPIRNVAIIAHVDHGKTTLVDALLKQSGIFREGEDVPDCVMDSNALER
ERGITILSKNTAVRYKETLINIVDTPGHADFGGEVERVLGMVDGCLLIVD
ANEGPMPQTRFVLKKALEKGLRPIVVINKIDRAKADPHVAVDKVLDLFLE
LGADEDQCDFTYLFASGMGGYAKESMEAEAVDMQPLFNAILQHVPPPVGD
INKPLQLQVTTLDYSEYLGRIVIGRIHNGTIRAGQQAALVTENGSIVKGK
ITKLMGFEGLKRVEMEEATAGYIVAVAGFADAYIGETITDPTEPQALPLI
KVDEPTLQMTFWVNDSPFAGQEGKLVTSRQVRDRLFRELETNVALRVEET
DSPDKFLVSGRGELHLGILIETMRREGFEFQVSQPQVIYREINGQPCEPY
ELLVLDVPADAVGSCIERLGQRKGEMQDMQPGSGDRTQLEFVIPARGLIG
FRGEFMRMTRGEGIMNHSFLDYRQLSGDIEARNKGVLISFEEGVSTFYAM
KNAEDRGSFFITPGTKVYRGMIVGEHNRPQDLELNVCKTKQLTNHRAAGG
DELVQLQAPIDMSLERALEYIGPDELVEVTPQSIRLRKMSKKLAKR
>Ava_C0163 Multi-component Transcriptional regulator, Winged helix family
MKLLIVENDRDTAAALTTSLVAQQFTVDTASDSRSALELAEATEYDLIVL
DVMLPDENGIRLCRQLRTQNQQEPILLLTRKVNPADRIAGFEAGADDYIT
KPYELSELLARIRALLRRGSTVLTKVLCWGQLQLDPNNCEVMCQGKGLHL
TPKEYKLLELFLRHPRRIFDRRTLLDRICSIDECPGEEAITTQIRGLRRK
LQMAGLNSDPIETLYGLGYRLKSVPEEREQGSEQGHGDTETRGRGDTETR
GQGDTGNIFDRLSALPFGATSRHKSLPSGFGSDAPNVANAALTDSTGNGA
TPLKSGNPPTGVAPQVENATSKTPTSSPQSGSVQGAGSPHLPISAFSSSY
LLNANRYDAEAEAVAAIQQMWQDSQERLQGQLAKLEEAIAHLSTNSLTPD
GRQFAQTIAHRLIGSLGAFGMPQAAELARQIERTLKTPTAAVQSEEAVQL
KSLLGQLRQVIQQLPTFATTAPTPVLKSSDRVVLLIDDDTDLIERMQANA
SNWSIHLETVTDLTLARQRLQYLTPDAIILDLTFPNTTESGLTLLAQLKH
QFSTIPVLVLTGLGDLTKRVEVTRLGANAFLQKPATPTEVFQAVSQLLHR
IDTINARLLIVDDDPALLSILEAQLQPWGFQVTTLADSSQFWQYLEATTP
DLLLLDVAMPGFSGIELCQVVKSDPRWSRLPVLLLSAHADADTLYRALAA
GADDYILKPIVEADLIQRILNFNSW
>Ava_3960 conserved hypothetical protein
MMPLNHYPSAIAQAAQRVNEVDSQLMAVQQQINRFEGNADRVAAFEMDLK
NDAQRRARRFEVLLVNQEYQKAMDTLIQLTGEKANAIAHLEYLRNQFSVA
KLEARLKIAQQLTDFESRELVGL
>Ava_1954 Periplasmic Sensor Signal Transduction Histidine Kinase
MLQLIHNVFADNLFIPHGHCYLWQPGLVWLHTLSDFLIAVAYYSIPITLV
YFVRKRQDLPFKWIFLLFGAFIVSCATSHVMEIWTLWHPTYWLSGFMKAI
TAFISIYTAIVLIPIVPQLLALPSPAQLEAANNRLKTEIIERKTAEAALL
QIKADLENRVEERTNQLHQSMLASLATAAKAKDQAEKLQVALNDLANAQV
QLIQTEKMSSLGQLVGGIAHEINNPVNFIYGNIHFIYEYTKALWQLIILY
QQYYPKPAWEIAAYIQEIDLDFVQNDFEKILASIKNGADRIREIVLSLRN
FSRLDEAEIKQVDIHEGIDNTILLLKNRLKGQGKHPDIDVVREYNNLPLV
ECYPGQLNQVFMNILTNAIEAAKESANKPLIQIQTKALDSSQVMIQISDN
GCGMTEEVRNKIFDPFFTTKPIGSGTGLGMSISYQIINKHGGTLKCVSAP
NEGTEFIICIPTRLKSST
>Ava_3170 Putative diguanylate cyclase (GGDEF domain)
MSGISPYSLSKKPPLILVADDDKTIRMLLREAMEKEGYRVVEVTDGKQCL
DAYEAVKPDIVLLDAMMPVMDGFTCCKQLLQIARNNLITALANLDTDSGL
GSTVISRLWERTPILMITSLNDAESVDRAFEAGATDYITKPIHWAVLRQR
LRRLLQQAQVYKQLEAANMALQHLANVDGLTGLANRRRFDNYLNTQWINL
VQKGAPLSLILCDIDYFKFYNDQYGHPAGDICLQKVGAVLSYKAQKHQDL
VARYGGEEFAVIMPYTHAKGAIYVAHTIQTSVRDLQITHDKSAVSQHITL
SMGVATITPTWESSPSDLIAAADKALYKAKESGRDRICQWKGSQ
>Ava_0613 Periplasmic Sensor Signal Transduction Histidine Kinase
MNNIKKNWINIDPFSLQLRLTVGMASFSALVLGSLATWTSWKMQQILIDS
RKHEVEQIAKRLPQDLQIYSRMMQPEMSLQKAINNFANTNTLIWFKNSNN
EILSKTENLDLLPDSLVAKLMKLTQMPIKAQVYQIDPSYFVVCGTSIKVQ
GKLLGELFVVKDITREQTMFVAMVRNLGITSILAIIILTVAIAFYIRRSL
QPLRQLSQMTAVISAEDLGQAQLYLDNAPSEVKELAQTLTMLLSRLAQSW
EQEREFVSNVSHELRTPLTIVYGYLQSVLRRQNNLTPLQQEALEIAASEA
ERTIRLLQDLLDLARADSGYLYFQMKTYVLNDIVAEIVVMAEKYSDRLIT
IESTISPIEVKVDYSRFKQVLLNLIDNAVKYSEADTPITFKLDQLQDTAI
IQVCDQGYGIPLQHQARIFERFYRIDESRSQATGGCGLGLSIVKTLVEGM
GGSVSVQSKLGEGSIFTIILPR
>Ava_0647 Multi-sensor Signal Transduction Histidine Kinase
MQSLPQLLWPPCLESVIDLSPLTVEPEMPLSDAVSQMAKQGAAIVVVANT
QILGWLSERDVVKLVALGVDLQTTTISQVMNTSIIFFQVAQFEDIGAIIS
LLRQHQSSCLLVVDEQEQLMGTITSESIYQALGAATELNSQEELETSQQD
FQLLKSAVVNPLDAIGASDESLWRVANTAPILIWISATDTSCIFFNKAWL
ELTGSTLEQEIGKSWSEKLHPEDLQGFLDVYLSAFHTHQFFSVEYRLLGL
NGEYLWLLNIGVPRFTSNGDFAGYINSCIDITEHKQYFAALEESTNRLKL
ALEATNTIYWERNLSNDQLFFLNPVIEFGDSEELTHSEVMSFFHPDDREK
VDMAAQEAIANCSCLEIEHRLPVAGQPSKYKWFLSKSTILTDTTGKPTRM
IGISMDITDRVEAQDALEQANQELERRVAERTLALQKANRQLLAEIGDRQ
IAQEQLRQSQQMLQLVIDTIPHCVFWKDRNSVFLGCNRKFAKLLGFDYPE
NIIGKTAHDFLANLQDADLHRQSDVRVIETNTPEYHIVEPLLKPNGQKIW
LEKNKIPLHDPKGNVVGILSTLEDITERKQVQEALEKSEERFRFLAESIP
QQVWIARPDGYLEYVNRRTLEYFGNVPEAILGWKWQQSIHPDDRNRCLEI
WQHCVATGEPLDVEFRWLRTTDQTYRWHIGRALALRDSQGNIINWFGTNT
DIDDRKRTEEALAERVKLSDFRSAVDTILTQSYTLQDLMHGSADAVVKHL
NAAFARIWILNKQENLLELQVSSGRYTHLDGSHRCIPVGQCKIGLIAQIG
KPHLTNSVQTDPLISNPDWAKQEGIVAFAGYPLIVENETLGVIAMFSCQA
LSESHFQALGIAANQIAIGIKRQQTEAALRHSEERFRNLVETSSDWVWEV
DENAIYTYVSPKAKDILGYEPQELLGRTPLDMMPPTEAERVMKIFNSIIA
AQQPFKCLENTNVHQDGHLVVLETSGVPIFDAVGKFCGYRGVDRDITARK
EVETNLYQTQQQLQVILDNSPAIIYVMDLQNRFILVNQQYEKLFHTTQSE
IVGKSVYETWPDDIAYQYAINNRQVITTGMAIEVEEMVPQEDGLHTYLSI
KFPLKDRNGIIYAMCGISTDITERKLAEDSLLRFHKAMESTSDAIIFGDI
LNISNYANPSFQELYGYNLEQLQAAGGVCTIFQEPQKQREIMARVMKGES
WRGEVAMRSRDGHLLQVDLRADAIRDSNGKIIGTVCIHTDITKRQQVEEG
LKLRDRAIDASSNGIIIADASTPNRPIIYVNPAFERMTGYSSDEVIGQNF
RLFQSADIDQLGLRELSTAMQAGKACTVVLRNYRKDGSLLWNELNISPVY
DQTGQLTHYIGIQTDITERKQAETALLVSQQRLQYLLTSSPAVIYTCKTC
GDFGSIFVSNNITTITGYEAQEFIENSDFWFNHIHPEDAPSVLKKLSSVL
EAETYKLEYRFLHKDGTYHWLYDQRRVVKDDTKNPVEMVGYLIDITDRKQ
LEEYLKVALEKEKELSELKSRFVSMTSHEFRTPLSTILSSSELLEHYRHK
WTEEKQLTHLHRIQTAVKRMTEMLNDILIIGKAEAGKLEFMPKPLDVVAY
CRNLVEEIQLNLNNKQVDFISEYQSMSCCMDEKLLGHILINLISNAIKYS
PVNSNVQVKFYCRDQCAVFEVHDWGIGIPAEDITHLFESFYRAKNVGNIL
GTGLGLAIVKKCVDVHEGEISVSSNSEIGTLFTVNIPLKQQ
>Ava_0463 Possible Transcriptional Regulator, Crp/Fnr family
MAVTLYSSIATPHNKNTHHYFTRRTFLPDQQNSLWKIEAGFVRTFTYLEN
GTTVALGLWGPGDILGRALSKLEPYQMECLTKVEATIVPIEEWKNPTDTL
LAHIQQAEELMVIRSYKKVDTMLIKLLAWLSKKFGSEVDKGRLIDMRLTH
EDLAEMLGSTRVTITRILGQFEEEGLINRLSLHRIVLKEEDIWYYEI
>Ava_0939 conserved hypothetical protein
MNKPIVWIHGDCLSPLNPALQEYPDAPAIWVWDDALIEEWQLSLKRITFI
YECLLELPVEIRRGNVAQEIIGFAKEHHADLVATANSPSPRFDNICDEIE
RSLKLEVWEVEPFFDYDGYIDLKRFSRYWKVAEKYVFE
>Ava_A0016 hypothetical protein
MEDRSIKIGKNIGSPSNTGYIGGDVINEVKDSLNTYTQEQKQRLSEAAAE
IQELLRQLEKSYPTDTTTGKMTVATEAIKHIDSNPKLHDRILSALKAGGV
QALAQLLNHPAASFVISALEDWQKSKDI
>Ava_0055 PAS/PAC Sensor Signal Transduction Histidine Kinase
MFPEFQHQELQSCCQQGDRLMVDLQKTQQELKETQGKLSLKKSLKEIADI
KFALDQSSIVAVTNHQGIIEYVNDKFCQISQYQPEELIGKTHRIINSGYH
SPEFFQQMWLTISQGRVWKGEVKNLAKDGTYYWVDTTIVPLLDEQGKPQQ
YVAIRNDITARKQAEITLKQSLKEIADIKFALDQSSIVAVTNHQGIIEYV
NDKFCQISQYQPEELIGKTHRIINSGYHSPEFFQQMWLTISQGRVWKGEV
KNLAKDGTHYWVDTTIVPLLDEQGKPQQYVAIRNDITARKQAEAELSKQA
KELEQALKQLQLTQLQLIQSEKMSSLGQLVAGVAHEINNPVNFISANLKH
ACQYTQNLLKMIHLYQNYYPEPALEIAEEAEHLDLEFLLADLPKLYSSMT
LGAARISKIVTSLRTFSRLDESDLKAGDIHEGIDSTLMILEHRLKSQQNR
PDILVIREYGNLPLVECYAAQLNQALMNILINAIDALEEKYEQENYQQVT
PTIHICTEISSYKQITIRIKDNGVGMSDEVRQKIFDPFYTSKPVGKGTGM
GLSISYQIITNRHGGSLECISSLGKGAEFIIAIPIHLMKNT
>Ava_1750 Possible Transcriptional Regulator, Crp/Fnr family
MQSPSSFSEASRPFLTWQRILDWAQEHYRCRTFSKDERIPARPGLLYLVQ
RGAIRMVGTAQVSATASQLTSRRINRTPEEAFLGFVGAGQPFEIVAQSPF
TLQSYAHVDQTAVLWMYWHDLDNWPHFRREVMDAFRYQHQRKLLWLSALG
QRRTIDRLLGFLTLLIEEYGEPAMSETDPDVIRGYCLPFPLTHAQIGSAI
GSTRVTVTRLMGKLRQRGLILTQGDNLICLPAESINRAS
>Ava_3234 Putative diguanylate cyclase (GGDEF domain)
MRLIEILEAKPKSFSTLLSIFTVSLIGLINYCISPEISVSILYLLPIGIA
AWFVNKHTGFFVAVSSDITNLVVNQIQDQYHLHPLIHFWNALVILSFFLF
VSHLLSQLKTTLINLEKLARTDNLTGLTNRGFFLDIVNSEIEKSLRHREP
LTLAYVDVDNFKQINDQFGHGFGDRLLQIIAKSTTNTLRKIDVIARLGGD
EFAILLPRTSYESAEVVLHRLHTVLLASMKKENLSVTFSIGAITFNNPPK
SVAEIIEIADNLMYLAKKKGKNLLQHELCDWKVESEDWKVVNSKF
>Ava_0219 Serine/Threonine protein kinase
MQVYCSKQHANNGGNRFCTHCGEPLPLAVKQVVDNRYRIIRQLGQGGFGR
TYLAEDIKKSHKTCVLKEFAPQVEHKEDLQKAKELFEREANVLKKLQHSQ
IPRFHGSLQAKIGTKDFFFLVQDYVEGDNYLQLLEQRQTQGKTFTEEEVI
TLLRQILPVLIYIHSQNTVHRDISPDNLILRRSDNLPVLIDFGGVKQLPA
SQGFWSTKLAGNNTLLGKKGYAPEEQLRQGKVFINSDLYSLAVTALVLLT
GKEPQKLYDSYQGVWRWGKEINASIQLESVLKRMLAYKPGDRYQNAAQIL
TDLPSPSSLTKPPTTHLTKIKTMVVSPGRKVTVLAGKLHNKTQAVSQKLP
LPVWLRPFAVSFGGTALVVLTGAGTWALVNSVVRGVSSITIPSISLPELP
SLPNPLAQPVSDKNKTSSSEVLSRRQQLEIPETFFIQITDSLFYAQKPEL
KGRSLTSKPEDAPLRDQWHAVAGEFLNKIEQANLSTAARRKLGSYTQKDY
ENWRRQARSGQLGNYTASQLNKDTNEKFDQLFPGQQRGKLNQQTFGQVWY
AIAADQVSKAQSK
>Ava_4855 Serine/Threonine protein kinase with WD40 repeats
MLCCLNPNCSMPQNPDGKMYCQRCNTQLIPLLRGHYRIIKVLSDEGGFGR
TYLSEDIDKLNELCVVKQFAPKVQENSAMKKAVELFKQEAQRLQHLGEHH
QIPTLLAYFEQDNYLFLVQQFINGNNLLQELRQGVVYNESTIVEFLLDLL
PVLKYIHERGVIHRDIKPQNIIRRQSDGGLVLIDFGAAKQLKATMQTQLG
TTIGSLGYTPIEQMQYGKAYPASDLFSLGATCFHLLTGINPSNLFVEQGY
SWVESWQQYWNTLDSDRKEGEYLVKVLNKLLETDIQRRYQSADEVMNDLI
KQRSLLSRLKTTIPKSALFSTSWSASTSLTASTTKKQARKSLNGKFKQQL
LINTMSALLGLVGVGHLQSLPQLITKFSEISTQPYTLKGHASDVNSVAFS
PNGEFLASGSDDKTIKVWNLKTKQKIHTLPGHSGWVWAIAFSPDGKTLVS
AGADKTIKLWNLATGTEIRTLKGHSQGVASVAFSPDGKTLASGSLDKTIK
LWNLATGKEIRTLSEHSNVVANVAFSPDGKTLASGSWDKTIKLWNLTTNK
VFRTLEGHSDLVMSVVFNPDGKTLASASKDKTIRLWNLAAGKTIRTLKGH
SDKVNSVVYVPRNSTVLASGSNDNTIKLWNLTTGEIIRTLKRDSGYIYSV
AISPDGRNLASGGSAENIIKIWPMSW
>Ava_0355 PAS/PAC Sensor Signal Transduction Histidine Kinase
MSLNQRSPTVGGTPSLWHQTHTPQTILPKTPVYLELATESASHQEFDTAE
KLRRAQEELRWHRMMYDNIPTIYFSLDATGLILSVNDFGADCLGYTPEQL
LQQPIVQLFAQSDQQRLSNAFISLCKTAPDDAVSYGNFLLNNPVNGIKAV
RITLRLILDEEKSSIKKSTILMLCEAITSLEPAEASSEDADNLVKNLPEL
PSNQGQRKELESLSHLQEEFFSTVSHELRTPLTNMKMAIQMLGITLHREH
NLFSATKKPTNEGSKAACYFNILENECDRQINLINNFLELQRLDTNAKPW
VLETIHIQQWLWRIVEEFKTRNFDICRQKLHISVSPSLATLTSNPCSLER
ILIELLTNACKFSPPEGEITVTAQIKSQNIVLQVINSDVEIPQSELPHIF
DKFYRIPSNDPGKQGGTGLGLALVQKLIKQLGGTIEVESGSNRTCFSIQL
VLQQPKIVE
>Ava_4293 Response regulator receiver domain protein (CheY)
MTVHLLTKSHQFHLQPLKRILIVEDNDINRMLLSDYLSYSGYHVQSLSDG
SNFFKTIEKFQPDLILLDLKLPDVDGYYLLEQIQQQQEFARIPVIVVSGF
AFKVDQKRAIDLGARGYFVKPINLNALLIKISQELVVNCI
>Ava_0648 Putative diguanylate phosphodiesterase (EAL domain) with Response Regulator Receiver modulation
MIKILVIEDEESVRENILDLLQAEDFHTVSAANGRIGINLALAEFPDLIL
CDMMMPEVDGYGVLSALRQEPLTATIPFIFLTAKSAKADFRQGMDMGADD
YLTKPFTRAELLSAVMNRLERQATLKKYLINQNGIKISSPKTQLLEMSLH
KVIQQQKFQEFEVQYQPIVDIASGKIVAAESLLRWHSPELGFVSPSEFIP
LAESTGLIVPIGQWVIANVCHQIKSWHDSGVDFLTISVNLSAMEFNKPDL
IQRITESLKTNNIAPHYLEIELTESMIMQDLNSAIFTMNKLQSLGVRLAI
DDFGTGYSSLIYLKNLPVNTLKIDRYFIHNVAKDKQKSAITKALVEMAHN
MNMQVVAEGVETESELYFLKQNKCDAMQGFLFSRPLPAVEFENFLWNNKH
LSV
>Ava_1950 conserved hypothetical protein
MVASGVEVKISRLESIVEQIGEAVLSTTETIERLAERVENLSCQVEAQGK
QLQQQGYQIFALCDAVQSLAESQDDSLQKLTQLTQTLDRLTSLIQGEDEE
V
>Ava_2084 Serine/Threonine protein kinase
MIGKLLDHRYQVIRVLAIGGFGQTYIAQDTRRPGNPTCVVKHLKPATSDP
RVFETAKRLFNSEAETLENLGHHDQIPRLLAYFDENQEFYLVQEFIDGHT
LTEELIPGNRWSESQVTHLLQEVLSILEFVHHQGVIHRDIKPDNIIRRTA
DNKLVLVDFGAVKQLRTQLVTVGGQPTATVAIGTPGYMPTEQGQGRPRPN
SDIYALGIIAIQALTGISPTELQEDPQTGELIWRHLVNVSDRLAVVLNKM
VRYHFKDRYQTATEALQALQNALNPVSVAVSSTPAKPFNSSYYQPAKPSS
PVSRQQTVAVAPTNPVVTKPGRKDSHKSDPLPLLIGIVLAGGAAALVANF
YPNVKNFAANVLGNNATSGNKCLAVVAGNSNIRSEPSSINTDTVLQTIGV
NTNFEVTGKRTKRGWVEIKFNSSRLAWAHSDVIINNQQWISCLRDKGIAL
KTVDDSTLIAARPVPKRQPKLDPFINSAPQPEDSPDSQPTEAAQPQTDTT
KVVEQARRKYESGDLVGAIAMLRSIPANASAGIKETSAMINQWQQDWQKA
DALFNDINKALEDGQWDKVLEYKNQPEKLPNIKYWRDKLEPIFKQAAENI
AKQALPKTENQGELNNSMEESPKNEEESTNETPSSSELPQGGY
>Ava_3628 Two Component Transcriptional Regulator, LuxR family
MDRSATSATAMKEPSMKDHKRLLLIDDDPNLILLVKDYLEFRGYEVITAE
NGREALEILEHDVPDMIICDVMMPEMDGYTFVEQVRQNERTSWIPVLFLS
AKGQSADRVKGLNKGADVYMVKPFEPEELVAQVESSLKQTIRWKEHQAKG
GENGSRIQVPFDVQLTPTELKVVQFVARGLANREIAEELNVSQRTVESHV
SNMLGKTNLHNRTELARWAIENQMA
>Ava_1627 Response regulator receiver domain protein (CheY)
MSKRILVIDDEESLRDLACTCLEDLGGWEAIIVQSGREGLLKVQKYLVDV
VLLDVSMPDMDGFQVYEQIKANPKTQDIPIILLTAKVLPDDYKRFAQLDI
AGVITKPFNPLLICEQIMQMLGWSD
>Ava_1629 Multi-component Transcriptional regulator, Winged helix family
MKILLVEDDVITATLLREVLTAEYYTVELATDGQNGLTLATLSNFDLILL
DLLIPKLDGINLCRQLRAQGIQKPILLLTAKDQSADVVKGLDAGADDYVT
KPYDISELLARIRALLRRGKTELIPNLLSWENLDVNVISAEVTYKGQPIS
LSPKEYSLLGLFLRNPQRIFSRSEIIDRLWSIDATPSEGAVTNLIKDLRQ
KLKMVGMSAELLETVYGLGYRLKMPPQTQDGEQSRKTDGLRKTKNQTAIA
AINKTIERYKDTFAQRVTLLERAEQALHTGQLLPELRQEASNEAHKLAGT
LGSFGYETGSKLARAIEHLLMRDENLALEDAVQLSELIGQLKEALSQSPI
SFTIEQLEPVPLPLVLVINDESFANQLKIEAAVWGVRIEVALNWESYQQS
FSQFPKVILLKINGQKSSQKSLKLLEQLKQQFPNTPILVIAEQDNLMQRV
AVARLGVQRFLTKPTNTEVFQVITQMLAQFQGSQGKVMVIDDDPVMLDIL
SNLLKPWGLAVKTLQNPQKFWETLITTTPDLLMIDLEMPTYSGIDLCRVV
RQDSHWGNVPILVVTVHTDIKSIQQVFAAGADDFIGKPVVGPELITRVIN
RINRSRLQQKLKT
>Ava_0649 Response Regulator Receiver Signal Transduction Histidine Kinase
MNKILVIEDDIHVRQNILDLLEGEGFNILEAHNGLLGVQLAQEEIPDLII
CDVMMPELDGYEVLKVLRQCPETAIIPLIFLTAKSDKNDFRQGMEMGADD
YIIKPFTRAELLAAIACRLEKHITIKQENQRKLDNLRNSIALSLPHEMRT
PLNGILGFSQILMEESDSLDSQAIQEMAESIYLSGERLFSLIQNFLMYAE
LEVMGTDPQQIKLLQSQTTIFPNLTLMEIISEKAKKAGREADLRLELHPC
NVRISTAKIAKIIEELLDNAFKFSPPGSLVQIKNQVINNCLILSFIDHGR
GITAAQIAELGAYQQFERKLYEQQGSGLGLTIAKRIAELHGGKLKIHSKP
QEKTIVQVALPCSQRKEDYCDNTYYQKSSIIGIRLDH
>Ava_3449 extracellular solute-binding protein, family 3
MNNGCNRWQIISRLHLILSAIIICWMISATGLAASAAELPEIQRRGYITV
AVKDNLPLLGFKDAQGNLQGLEIDLAKRLAADLLGKADAVKLQPVNNRDR
LPVVFNHQVDLAIARVTATESRSRLVSFSVPYYMDGTYLITKDVSVQQIN
DLATRKIAVLNNSSTIAEVRYYIPSAELVGVNSYQEAQAAIENNSVAAFA
ADGSLLSGWVRDNPQYRLLPTKLSTAPLSVVMPKGLQYDELRREVNEAIA
SYIAQGWLKERISHWSIVNSQ
>Ava_4433 GAF Sensor Signal Transduction Histidine Kinase
MSAINLKKIFSKKELPLLLQNLVEQIKVAIDVELVDGTKLLSIGEQTSQH
RHSIEVSGEIIGWVVGEEQASIVASLLSFLAKQEAEKKELAKELLERYQE
IDLFEDISTQLTRSLDTRQIAQLVLKELSQLMESSAGIILLLSPDKTAFE
TIAEFGQLFHQNQPQPGQGIIGSIVQSGRAELINNLPADRRIYEQKNVNA
LICVPLRAKDRILGAIAIGTTKTEAYKAEHLKLVSIFASQTAIAIEKALL
YEQSTQATAQAKAQTEKLQQALHELQLAQTKLIQSEKMSSLGQLMAGVAH
EINNPVNFICGNLRYVAEYANDLLYLLHEYQKFLPVAPSEMELDLDNIDL
EFIRDDLPKLLDSMKVGTDRIVEIVKSLKNFSRHDEAEMKTVNIQDGIDG
TLMILRHRLKAGPNYSEIEVVKDYAQLPLIECYPGQLNQVFMNILANAID
ALEELRVNSQELTVNNPKLWTMDYGLLTKPQITIRTEALDDQWVVIHIAD
NGSGIKEDIMGRIYDPFFTTKEVGKGTGLGMAISHQIIVERHHGILKCRS
QPGQGTEFWIQIPVNCSAMEVAKEQNRLIPDLKTATLPTPTSELSPTADA
DGFIPSTTPTFKPTELLLRHTQLIRQLSEQSPGVDTASSEQIYQIFQRNP
ISLKLYATLLSWFCCSQPTPINHQGNHNHV
>Ava_2028 Two Component Transcriptional Regulator, LuxR family
MIKVLLVDDQNLIRQGLRALLELESDIEIVGEAENGKIAIDLIPQFHPDV
VLMDMRMPIMDGVAATQEIQRNFPSVKVLVLTTFDDDEYVKAALQNGAMG
YLLKDTPSEELAVAIRAVEKGYTQLGPGIVKKLLVQFQSTPNHTPPAPTN
LADLTPREKEVLRLIAAGANNKEIAQQLYISEGTVKNHVTNILNRLSLRD
RTQAAIIANTYLSHLNEPE
>Ava_0820 FHA domain containing protein
MNALTLQWQDGGQNKTQQIYEQQPSKNPGTVRIGRDPLRCDIVLTNPTVS
GLHVEIFFHSQQQNFYIRNLRSQNPPLIDGQQLIQGEKPLNQGSIIYLGQ
AQLHITNITINTIAATVLSLPQPPIARPQPVTPPLRQQPSPSPIHHHPAT
PPGVYGLECPKCHRVSSLENLPVGCPWCGTSLAAAVSVLVAPN
>Ava_2148 Multi-sensor Hybrid Histidine Kinase
MPVSNTKPSLQRQIKTMIRSSVQTAQKLPLRLILVVPFVLQIFTAVSLVG
YLSFKNGQKAVNELADQLIVKVNGLVDQHLDTYLAVPRQINQINVDATNL
GMLNLENFQTTGRYFWQQMQVFNVGYISFANPQREFIGVERLDKGSLLIN
EVSQEKGIGKLYVYNTNNQGDRQQLIAVKDYNPHVEAWYADAVKVGKPIW
SQIYSWEDKPEVLSISASYPINDSNNKFVGVISVDLILSQINSFLANLKV
GQTGQIFILERSGMIVASSTSEAPYKVISGKAQRLSAHQSQNYLLRETTD
YLQQKFGQLKNVKSYQETVLQLRHERHFVQVRPWKDKLGLDWLVIVVVPE
SDFMAQINTNNRTTVLLCLGALIIATAMGVYTSRWIARPVVQLTQASSAI
ASGNLDQEVTISGLKELSMLATSFNQMAGQLRDSFAELEKTNQELENRVA
ERTAEITAAKETADAANRAKSEFLANMSHELRTPLNGILGYAQILQMDSN
TSDEQMQGLNTIYECGSHLLTLINDILDIAKIEAKKLELYPKEFDLRKLL
LGACEMCRIKADQKELIFKYHLNNRIPANIFADEKRIRQVLINILSNAIK
FTDHGTVTFDVEVVACTGTKLITNTNQLLPVHQLRFHIEDTGIGMTDEQL
KKIFLPFEQVGDNLHKSEGTGLGLAISSQILELMGSDLKVESVYGKGTKF
WFDLDLPIVDTGKFSLSVEGQKNIIGYEGKTRSILIIDSSWENRSIFANL
LSSLGFKLIEVSNLQESLDKIKTEHPDLIIADIAMPEINNLQATKKMRSQ
VEFANLVIIASSASVSEYTRQQSQEAGYDDFLAKPVKVEELFNMLQTYLS
LKWIYSLNDDSSAKISTTEEIIFPPPTELFNLYQAAKAGYVVGIQEEIIR
IQQLDKRYTRFAVKVSELIAEFEDEAIVAMIQPHLSY
>Ava_4432 PAS/PAC Sensor Hybrid Histidine Kinase
MSSQLDQCNRLLWEKCPVGLVLWRKNGALIDVNPTYATILGRTVPETLNL
NYWQITPENYLASERTILEQLEQTGCHQAYEQEYLHKDGHLVPVKVSTVM
IEKDGEKLMWSSVEDISNIRQTQKERQQSEKILKQSEARYRSLVTTNTQI
IWVSSPEGICFELKDWIAYTGQTLAEAENGGWIDAVHPDDRGYTGEAWGI
AVANRSQYQIEYRIRGKDGNYRYFWVWGAPVIEEDGNVREWIGTCTDIHD
RKLAEAENQRLKERYRSLVTASSQIVWGTTPEGWGISSEMLTWIAYTGQN
EAEVEGWGWLDPIHPDDRTRSLEAWNAAVANRSIYQTEYQLRGKDGTYRY
FSVCGVPVLKQDGSIQEWIGTCTDIHDRKLAEMALRQLNQQLEARVAERT
AALQNTLAEAQGLNAILDNLADGLLVVDTTGQITHYNPAFLAMHGLTANT
LNGHYQELPIFGLADLIEHTRSHPGEVFTADVALAKDRIGQAVGTAIFKR
TDTQEVAACFGSALLIRDVTAEKEIDKMKTDFISTVSHELRTPLTSVLGF
ASIIQEKLQKDVFPILSTEDRKLQKTIKRVGDNLNIIVSEAERLTSLIND
VLDIAKMEAGKVEWQMQPIDPGELLDWATTSTAALFETNGLQLLTEIESG
LPQIIGDRNRLLQVLINLISNAVKFTEFGSVTCRVKQDKDGVCISVIDTG
VGIAPEDQPKVFEKFRQVGDTLTDKPKGTGLGLPICKQIVEHHGGRIWVE
SEPGHGSVFSFHIPIYASNHNTNANLNLDALVRQLKEHVITANQVCSENR
KTILVVDDDANIRELLRQQLENEGYNVREAKDGMDAIHQIKISSPDLIVL
DVMMPQINGFDVAAVLKNDPLTADIPIIILSIVENKERGHHIGIDRYLTK
PINTEELLNEIGSLLSQGISSKKVLVVDQNASTLKTISDVLQTQGYNVIE
ASDPQECIRKALSAKPDMIIIDSIFSQEADLVKTLKFEKELENVFFIMLS
DR
>Ava_0062 CheA Signal Transduction Histidine Kinases (STHK)
MSKDKELEIQMQFLEEATDYINTLEGVLLEIDTSHRIDLEKINGALRAAH
SIKGGAAMMGFRALSDLSHRLEDAFKVLKTRKNSLEIDTKLQSLLLSAVD
WLRQIVQLLGEGNAVEEDWLATFCHPVFDELRDRLGDPTPEDAATMLSPE
EGQDIIPLLFESEIEGCLQRLESVLADQNQPCLQEEVAIMAAELGGLGEM
LQLPAFTQLCESIKYHIENANGNVSEIAQLALQTWRRSQALVLTNQRDKL
PTELQFGELVHIPVYTPSLPQFQADKLSETPIESNFIPEDLTVSKNNNHH
PLNIIDFPEILTEFAKENITTDYTLIANKDREHQENTVRVPSKQLEEIND
LFGELIIQRNGLNSQIERLRKLVRNLNQRVHTLERENQELRTIHERKTTK
DLVNAHHGAEYPQTQDPESEFDALEMDRYNELNLRSQTVVETIVQVQEVT
TDIQLSVDDTDHVARKLNKTSKQLQTKLNHIRMRPMSDLVERFPRAIRDL
NVEYGKNVQLKITGGNTLIERSILEALNEPLMHLLRNAFDHGIEESATRQ
ALGKPEQGLIEITATHRSNRTIITMRDDGRGISLDKIRTRAQGMGIDAAL
LANATDEELLSLIFEPGFTTSEQVTALSGRGVGMDVVRNNLKLVRGDITV
DTELGVGTTFTLSVPFTLSIARVLLIETNKMLLAFPTDVVSEIFLLQNEQ
VFPMAGNEVLNWQGTMLPLIRLGRHLEFNCPRYDSPELETPPAINAHSVL
IVKGNNQPVAILVDRCWGEQEVAIRQVEGNIPLPQGFSNCTILGDGRVVA
LVNTNELLYKIATNQHPTKNLQSSSATLKTPFLFFDSAKLPAPPTQNKGT
ILIIDDSINVRRFLALTLEKGGYQVEQAKDGEDAWEKLESGLKVKAVICD
IEMPRLDGYGFLDRINSNVDTKNIPVAMLTSRSSNKHRQLAMQLGARAYF
SKPYNEQELLGTLEELIFNVAVSS
>Ava_0224 Putative diguanylate cyclase (GGDEF domain)
MTMTILVFGSYDFLTKLPDQIHKRATDKLVVITDFHQAASQIQTASPDVI
FVQASLKGSVELCSWLKEQTQLSCIHCILVEDRPQQLAQRSQNGWEWEFE
MTATALHQGADAYIWQLPTEVTATHNLILGQLTVGLRKAQKYRDLLQKNH
ILSAIALADSLTELNNRRALEWDLPRQITKARNQNLPLSLVILDVDYFKK
VNDQYGHLIGDRLLQLLCTRLRHNLRSQDTAFRYGGEEFVVILAHTTGEE
AMIVAERLNRIVGEQQFSINSKLMISVTISLGVACLGTDDDEQGNSLLDR
ADQCLLAAKASGRNQVIGEHRLSKLSSLKAVS
>Ava_4928 Multi-sensor Hybrid Histidine Kinase
MTDSMKIAIMRRWLMISLLGLFALVIAHGMALIYRIQPGVSLWFPPSGVA
IALTFWFGPCGIILTGLASFLMSPFWGLHGWERLIAFVDIIEPLSAWLLY
RRLWKGSRTINTLKDATLFTVSAPLVACATLATIGSLSLVAIGKMPLAGL
SHNIPHWWLGNAIGIMAIAPTALLVFTPYFQSQGWLHRTEPLNSGFVSRN
FRPSLHLLLEFSAILLLCLAIATLTVAETNQNGFKLQQLSFLGFVPVLWA
ATRFGVTSGMLTSSFCVLVTLFAYLVAYPKAMYLATFPVQAEVLHVHKLS
LLVQCAVSLFVGIAITERSSIQVELAVEKVRRGEYQSRAELSEKLIQLNE
SLVEINDCLEESHREKDELLRREQALRSRLSNILSSMTDAFIAVNRDWDI
TYCNHQAAKIQHLEPEDLIGKNYWEQWARTKGTDFEREYRRSLAENIPVH
FEVLYELWDMWFEVHAYPAEDGLGIFFRNITERKQAEQEREYLLMREQIA
RSEAERANRLKDDFLAVLSHELRTPLNPILGWATLLKKRNLEEATRRRGI
ETIERNAKLQIQLIEDLLDVSRIQQGKLNLNIQSVNLVNTIEEALETVSL
AIEAKNIDVKTALNVNVCMVAGDAARLQQIIWNLLANAIKFTPPAGQIQV
ALERVNNSAQIQIQDNGKGISSEFLPYVFEYFRQADGTITRQFGGLGLGL
AIVKHLTELHGGTVKAESAGEGMGATFTVNLPLMLNAPQIVPQVGQPDNT
WGLAGLYILVVDDDVDTGEFLTLMLEQSGAEVTAVTSAGEALEVIARTKV
DLLLSDIGMPGIDGYMLMQLIRAMPSAKGGKIPAIALTAYAGEINQKQAL
AAGFQLHLVKPVEAEKLLQGISEVLAASPPEFSYVSVEN
>Ava_B0191 Response Regulator Receiver Hybrid Histidine Kinase
MLNVLLIDDNINDRLLAICSLKKEFADLQIAEIKNPQELAQALENGVFDV
VVTDYQISWIDGISILRTIKQHYPNCPVVMFTSSGSQEIAVEAMKSGLDD
YVLKSPKSSSRLATAVRLAIEQAETRANAEAANRLKDEFLVTLSHELRTP
LNAILGWAQILLKQTPNSSTTKRALETIVRNAKTQARIVEDILDISGIIT
GKFSLQVAPVDLVAIINTVIASVNPAIATKAIHLEAKLAPLDGQVLGDET
RLQQIFGNLLLNAVKFTPEHGYILLQVKQVNIDAVITVKDTGIGINAEFL
PFVFDRFSQADSSTTRSYRGLGLGLAIARQLTELHGGTIEATSLGEGYGA
TFTVKLPLMSKQFLETNYLTEVTYIDSNNIQDDCQVRNNKLCLTDLRILV
VDDEVDTRDLLISILEQEGSEVITAASAQEAMVAVCNSQFDLFVFDIGLP
QEDGYTLLTRVRQLEQQHNREIPAIALTAYAAKEYQQQALAVGFQKYLAK
PVEPDELVVAISSLLEINE
>Ava_4120 hypothetical protein
MLALAGRSPTKIIPRISNAQIRCIVLCASDPYAVVGVSQSFGVTPDLISG
IATSTTAGVELVEKLTGVVALTLPDHQSLPKLMQILKAKLAFN
>Ava_0612 GAF Sensor Signal Transduction Histidine Kinase
MVKAIDDGIFLQNQMWQRERLAIALLSSLNYRTGELSGYLFNIACGVSKL
LNVDWSVVTLCQQGFEKVLASNINMGVGEHVYSLHGSLTNTVIETGNSLV
VEDTSKHPEYGQPPEGYRAYLGIPLRTAEGEVIGTICSFHHESREFSPEE
IQFTELFAERAATAIDNYRLYKEQCQFNHILEAEVEKRTAELKATQSKLV
EKERLAAIGEFAAMIVHEIRNPLTTMIMGLKYSQKTILSSDAQERLSLAV
SEACRLDNLLSEILLYAKPQVLQICELEVNKFISELLILVRQMPEALSRK
IEFIPSSTSVKILADKDKLKQLFINTIRNACEAISAGEVVQWEVNISSPD
EVCINICNRGEPIPPEILSKLTQPFFSTKPHGTGLGLAIVQRIVHAHYGK
LSIESDITKGTIVSVRLPIATFQTLGYFEVYKDYTYQVTS
>Ava_3536 Cyclic nucleotide-binding domain (cNMP-BD) protein
MTSPNTVIWLRERTTLGILSSMVLDAIAQTLEEQVVPANSTLVLEATHPE
ALYIVQDGQLESETTNQNSSVLARGFLPGAVINLQELLLDELTPCKIVTL
TESHVWAIPTAKFRELISQYPEINQAFSRQLAQELAQVTSALTYEQERSV
ALRPYLVTKAQRGIVGTSRYAVRLREQIRGAAADRKSVEIFGEPGLEKDN
IATLIHFSSPKRREPIIKINCGILQTSGADLFGRAGGKPGLLEWLGEGSL
ILNNIQELPPELLQPVAQLLQTNTYTPVSRPGEPAATPRTSKARILLVSE
KTESKIERCVGHIIKVPPLRVRKADIKAQVEYYTSLYVRSRGVKKPHITP
EALRRLQSYDFPGNLKELKNLVERAIVQAGERRELTEEIFWAAEPKKKQF
RVNLLNLYPGLRRFLRSSWWPDKINYGFTVVAFAFIVCVLFLGPQTRDRN
FALNLFWAWWWPLILLIFPFFGRVWCAVCPFMIYGEITQKLSLWLFPRQL
KRWPREQAEKWGGWFLFGLFTLIFLWEELWHLENTAYLSACLLLLITSGA
MIFSALFERRFWCRYLCPIGGMNGLFAKLSMTELRAQQGICSATCNTYQC
YKGGPEKGEGMETDGCPLYSHPAQLEDNRDCVLCMTCLKACPHRSVEFNL
RPPGIELWTTHVPHNYEVALLFLLLGGIYLHRLPELLDWLGLQLDLTQFW
LHLGISILALLMPSAIILSTYGLIKIFNTRRKPRRFIELAYGYLPLVLGG
NFAHYLRLGLGESGKILPVTFATFGLSGEQLPILVAHPAVIAFLQGATLI
FSVLLTIVLTQKIARQPLRTLLWQHLSAIILGISMWIIIVL
>Ava_1716 PAS/PAC Sensor Hybrid Histidine Kinase
MAAGLGLGVVGITKADIEGKTIWEALPPETSSEVELPYRQAFAGISSRFE
APYGHRVYEVHVLPVRNDDGEIFAGMTITQEITERKQSELALQDALQLLN
LHIDTTPLAVVQWDCHLCVTRWSSTAEKIFGWRTEEVIGKYFQDLHMVYE
EDMTAVAEASNRLLSGQESQIIQYNRNYTKDSRVIYCEWYNSSITNEAGS
VTSVLSLVLDVTERIQAEKALRQSELMVIEERAQALERERAARIELERAS
RMKDEFLAIVSHELRSPLNGILGWSRLLRTRKLSPEKIEQALESIERNAQ
AQTQLIEDLLDISRIIRGNIRLLVRPTKLIPVIQAALDTVRPIANTKSIQ
IISRLNFDIGLVSADPERLQQVIWNLLSNAVKFTPEGGRVEICLEQVETN
VQIRVTDTGKGISPEFLPYVFDRFRQADATTTRNQGGLGLGLAIVRNLVE
LHNGTVSVASPGEGQGATFTVQLPLLPSYSTVTPEEPLLQRQTTWDAKVQ
IRGLKILAVDDEPDTREFLKTALEQYGAIVTTAASTSEALKLLQLVKPDV
LLSDIGMPNEDGYALIRQIRALSSEQGGNVPAAALTAYTRQSDRLLALTA
GFQIHISKPIEPIQLLKIVATLAGNNSN
>Ava_1223 ATP-binding region, ATPase-like
MLIKNQMGQPHKSIAAEQPILALGRVLQILREEDDVDVLIETTINYIHRE
FNYKLIWIASYDRLKHTLFGKGGIAPGSDINFLRRRLVLQPGDLLEQVVI
QQSPLGVADIRNEKRAGEWREVGTKFNIQGTIMLPMRHKNSCMGLLLLGS
ERWGYLLPEDAKARLMMVLGELAASLYQQEISLQQKQVKRPDEPLLQLLE
NIRNLNNLEERLKAVVEATHSFVSPSRTNIYWFERQGRYFWCRMGDQLVN
IGRETNREQSAAGMTVQDLSDLYYALSVNKIIWIGDARSSLEGQFTAKLL
QRLRVRSLLAAPIIWQKDLLGFLAVEGYEPRIWTEADKNFVQGAAGFLSL
VAPNDKIENIIKQIQEDSQLTSEVAQSIYTYQDWKETLRVCAAKVLHRFN
ATRFLLLHYDPDQNNYQVIYQTQPHHRRPLSCSFGLLSQTDRQMLKTANA
TVAVENVEADLRFFNWRPLLLEHGARSLLICNCTQDPKAEVLLVVTHTSH
RSWTNLERELLWVVSQQIGVVVKQWRLQKNNEQQQQVLQSIQECLQIVDG
TESENSETEKNHLECAALRQMASVFNCPLALLLSWSHGESTAEIIPGVIP
DNRFEVEVSAKLSIQYEAVIQWALVENSYLNVSVDHLPPETRQWLHGEGI
GQVLLMALRTGVDHQPTGVVLLADHRERHWPQHRLDAGKILIDQLAWLRR
QQQISQRLESTTQELRQLNWYKHRRLESVQRTTTNLLKQMYDLGVPTNDM
AHTRYQVLLKQLDHTFTSITSMVKLEQWQLHINWETMPIASLLKRSLERI
DKLVQEQKLWIGVHGLAQAQTEKEVTNSGALLKGVSTPANLSTMAIAGDI
VKFELVLYELLLAACHRSPNSSRIDIWCRHIDKQFLEVSITDNGKIPAEL
LTEIQQKTHNDILAFCNFAQSPNLNLLICQQLIQQLGGELDIYQSTDNRV
VSRLVLPLAEISS
>Ava_1559 PAS/PAC Sensor Signal Transduction Histidine Kinase
MITTSNQTSPESDRHPENIAKMAPVGIFHADISGNCLYVNERWCEMSGLS
KKQSLGRGWQVAIYPDDLQLIEVQAQFILSRQKSYKTELRLQDPQGKITW
VLSEAIAEINEDGRIVGYIGTVVDISERHQIEEALRESEERFAIMANSAP
VMIWMSGLDKLCNFFNQGWLDFTGRTMAEELGNGWVEGVHPEDRERCIHT
YTTAFEHREVFMMEYRLKRFDGQYRWIFDTGTPRFNSDGSFAGYIGSCVD
INPRKQVEITLQQRTKQLTRLNTILAKTTTLLQQRNQELDQFAYVASHDL
KAPLRAIASLSEWLEEDLADQLPEENQHQMQLLRGRVRRMEALINGLLEY
SRIGRVHTELTQVNVDSLLREVIDSLQPPASFQIQIQPKMPTLVTKRVPL
QQVFANLIENAIEHHTGVDGRVKISVRDLGKYYEFSVEDDGPGIPVEYHD
KVFVIFQTLEPRDRKENTGIGLAIVKKIVETEGGSINLKPVSGPGSTFRF
TWPKRSLE
>Ava_3865 Periplasmic Sensor Signal Transduction Histidine Kinase
MFNRSRRNLASWFSLAMGGILVVFAAAVYYVKVVDELEGVDRLLYKKTTV
MAASVKSELHNRQRRVDLDKVPLLGTKVEPLPDSQLVYAGWYDEQKRLVQ
FFGETPSDRLLVASGFNTIKINSELWLRQVTLPVYQDGLLIGYMQAAMPL
TDTEGALAEFRLVLAISVPITLGIIALTGWWLGGVAMQPIRQSYDYLQRF
TADASHELRSPLSAIVSNAQYGLLTKSTDPETQRQRLQKIFDIAQSMSIL
VNDLLFLARYQGRIPIESLQTVDLKILLLQIKDDFLTHPETQHIKLLFTL
PNHRISVLGDANLLRQAVINLLSNACKYTPEGGQVELQLFTQSNWAALQV
IDNGIGIPQNDVPYIFERFYRVDKKRSRKTGGFGLGLAITQQIIQSHGGK
INVHSVVNKGTTFQVLLPLK
>Ava_2675 Multi-sensor Hybrid Histidine Kinase
MSALWTYFFNSAPFIPHGHCYLWQTDLVWLHIISDGLIAVAYYSIPATLF
YFVRKRQDLPFYWMFLLFSGFIVACGTTHIMEVWTLWYPTYWVSGFLKAI
TAIISVFTALALIPLVPKALILPSPAQLERANKDLQNEIGERLKVEAELR
KYQNHLEELVNIRTNEITNANEKLQQEIHERQRIVEILRESEERYRYLAE
AIPQLVWTADANGECDYFNQNWCDYTGLTLEESLGSGWLAALHLEDLERS
YETWSKAVETGTLYENEYRFKRAADGSYRWLLGRGLPLKDHQGRVVKWFG
TCTDIHEQKQILEERARLLELEQTARAEAETANRIKDEFLAVLSHELRTP
LNAILGWSKLLQERKLEPARTFQALATIERNATLQVQLIEDLLDISRILQ
GKLVINITKVNLVIVILTALETMRLAAESKLIQVSTNFPSKMGQVMGDSA
RLQQVVWNLLSNAVKFTPKGGKIEVSLEKVDGYAQIVVSDTGKGIKPEFL
PYVFDYFRQADSSSTRRFGGLGLGLAIVRKIVEIHGGTVTAQSLGEEQGA
SFTVRLPILPEEDGNVTYEQHRSTSSITSSLPLEGIKVLVVDDDADSRDF
LTFILEQEGAEVTLAASALEVLQLLPEIKPDVLVSDISMPDMDGYTLIRQ
VRTWTAEQGGAIPAIALTAFARQYDREQAFQAGFQLHLPKPLNAEEFFAA
VVELVNGQ
>Ava_1566 Response regulator receiver (CheY) modulated Serine phosphatase
MVKILVIDDDPVVRTVLKRTLENQGYETTVVNNGEEGIIQAKLLRPALII
CDWVMSGLDGLEVCRQVKANPELATSFFILLTAKGAAPGEEKDRVKGLDA
GADEFISKPIEMIELKARVRAGLRLHQLNQDLQIQKQTLEMLNHDLQTQK
QTLEADLAEAADYVRSLLPKPLEGKVNTETLFIPSTQLGGDCFDYYWLDD
EHLAIYLLDVSGHGIGSALLSVSILNILRSQSLPNTNFYKPREVLKALNH
AFQMANHGDKYFTIWYGVYHCIQHQLVYASAGHPPAVILSGKPETGFQVK
RLNSLDLPIGFLPDVQFEDAIWEVKKDSTLYIFSDGIYEIREPDGKILGL
DAFIEILTNSSQKEPCNIHYILMQIMTLNIQQILEDDLSLLKITLG
>Ava_2851 Serine/Threonine protein kinase with WD40 repeats
MICCLNPDCLNPLNADGKKSCQSCGTTLVPLLRNRFRVVRVLSDEGGFGR
TYLSEDKDKLNEPCVIKQLAPKFQGTWSQKKAVELFAEEAKRLQELGEHP
QIPTLMAYFEQDNCLYLVQQFINGQNLLKELQQRKNYRPGEIQAILLDLL
PVLKFIHDRGVIHRDIKPENIIRCRTDGRLNLIDFGSSKQLTAKVQNFGT
SIGSHGYSPLEQIRDGKAYAASDLFALGATCFHLITSVSPFQLWMEHGYS
WVSNWRQYLRSPLTPELDFVLDKLLQKDLKHRYTSADEVIKDITPKQPLA
LPAAGQTSGKIPVPQTTYLSKSPKKYSLLRSVVLLSALVLLFGFSESWFS
QYLRIYSSLSARLTQNKAGEVVLAQPHKTTLRTISLANTLPSDENAFVSL
AISPNGQIIASCGSDRSIKIWQLATGEDISTLNGHSRKVNAVVFSPDGKT
LVSGSDDNTIKIWNLKTGQVIRTITGHSDAVHTLAISPNGKTLVSGSDDN
TVKVWNLNTGRLINTLTGHTFWVRSVAISPDGVNIASGSFDKTVKIWNLE
TGNLTHTLAGNGETVTSIAFSPDGNTLASASRDRTIKIWKVGAGTRVRTL
KGSTETITSIAFSPDGNTLASASRDQTIKLWNLETGEEIRTLEGHENTVT
TVAFTPDGANLVSGSEDNTMRIWRIGN
>Ava_1562 Response Regulator Receiver Signal Transduction Histidine Kinase
MSVVENNQIDRILAVDDTKDNLILVQTILESEGYEIDLASDGISALQKVE
QSPPDLILLDVMMPGMDGYEVTRRIRNNPALSYVPILLITAFHESSVVEG
LDVGADDFIRKPFDTDELLARVRSLLRLKHSLDEQKKMARQREDFVSRLT
HDLRTPLVAADRMLDLFQQEAFCKISPEMKQAIAVMIRSNQNLMQMVNTL
LEVYRFEAGKKTLNYESCNLKEIAQEVVSELTTLTNEKGIALKIDSTQID
NLGEKAGVVMGDTLELRRVLYNLVANAIKFTDTGGIEIRFFEPNNHWLTI
EIEDTGYGIAPEDQATIFERFRQGRNKRSGSGLGLHLSSRIVEAHEGMIS
LVSEVGKGSKFTVKLPKNI
>Ava_4431 Response regulator receiver domain protein (CheY)
MTQKILIVDDEPNIVILLEQALEALEDEGVELLTARNGEEALESIKNEQP
NLVFLDVMMPKMSGLEVCQIVKHDLQMTHVYIVMLTAKGQEFDKQRGMDV
GADLYLTKPFRPKEVLEKSMQILGF
>Ava_2809 Serine/Threonine protein kinase
MSGASLIGKTLRSRYYITDKIGEGGIGETYLAIDKDQPEDYQCVIKRLKP
QNTNQSTIMWLQRAFNREAVTLQRLGSHDQIPRLLAFFREDEEFFIAQEF
IHGINLRTEFSNSGKWSETQVISLLQNILEVLDFVHQNQVIHRDLKPENL
IKRSSDNKIVLIDFGAVKEIGTQIINNKGKKVSTSFIIGTPGYMPMEQLR
QNPMLCSDIYAVGMIAIEALTGLHSTKLLDSYTGQIVWRDRLKIREDLAE
ILDRMIAYNPHHRYQSAAECLQETLSLSQGLNHQRQTSISLSLSPICTII
RFGSFGRITTNEFIGKFLAITQNRKLVKTPGISLILASIVAIIVGKGIWS
QILINNIDAMADEISLPASRATKGHTPNINISKFLSYFINSSANLTKKNP
TDLPIIKPLVHNQSSSPVLSRLQTLRLENIQIHQVATPRTYNICNAPLQL
LQPNHSDRLNLDWQLDWTTKGNAHVGRLKMQGYSGKMRTISPDGKGGLRT
VEQTMQLYTSAKGYVLLGFNPMDVEKQQARRYKANNLIIRVEIDGSTTII
NCDDSGNISSAIAQEF
>Ava_2806 possible Sensor with Chase2 domain
MFRLNTRKIKQEIIILRQVAIPGMTVLFIIIIARLSGLLQGLELILFDTF
LRLRPAEITDPKIVIIGINENDIRSLGTYPVPDAEIASLIQKIQIYKPAV
IGLDIVKNVPIEPGHQELIKAFQQYQNLIGIEKVLPPDEISPPPNLPPKQ
IGFSDVIADRDGNYRRYLLLTASPQNPENPQDDKYSLALRLAQGYLATKN
IIIDTGKYNSYIRFADIELPIFSANTGGYVGENDTGLKMLVNFRSGKQPF
RFISLNDIKSSKFDPNWLKQKIIIIGVTAASSNDLFNTSATTSSKIHSQI
YGVEFHAHVTSQIINAVVNDRPLLKVWSDGWEYLWLVIWGVTAIIIARVT
ETFRRNLLTIILIIFCLISISYLLILLGWWIPLAPTLLILGINGLGISVF
AFHEYKQNQIKIQLSQHTIEHTFTLIHNGPLQTLANILRQVGTDNLQNDK
LILQLEKLNSEIRSIGEYLRIEALTPNESLRLGSRVKIDLKRPIHELFYE
VYTSTIARDDLEYFYNINVKVRTFEPIDEKYLNIEKKQELCLFLEEALCN
VGKHAKGVKRIEAIGKKERSSYTLMIKDNGCGLTSFSENKGMKQLKNIAK
KLGGNFKCESLYPKGTICEVTWKLTNNKNNYLN
>Ava_1917 Two component Transcriptional regulator, Winged helix family
MVMLSATNPKILVVDDDFGVRNLIYRFLSRKYQIESAADGKTALSLFEQF
NPALVILDWNLPDTSGYSLCQEMQSRNNVLVMILTGRTEEADKIKILAAG
ADDFITKPFSLAEIEVRVQALLRRIRSIKPSPSQRLIFKQLAINPEGREV
TLNDKPLNLTALEFNILHFLASHPGQAWSRPQLIQKIWGCDYVGDGRVVD
VHIGQLRKKLESDTSIPEFIKTVRGYGYKFEIPESTPI
>Ava_0508 Response regulator receiver domain protein (CheY)
MSTVLIVEDSLAQREMITDLLKASGLTVTHATDGLEALEAIKEEPPDLVV
LDIVMPKMNGYEVCRRLKSDPKTQNVPVVMCSSKGEEFDRYWGMKQGADA
YIAKPFQPTELVGTVKQLLRG
>Ava_0220 Serine/Threonine protein kinase
MTKLYCSKGHENYPGTRFCLKCGEKLVDNFFTQGIQPGLTLSDRYLIVRQ
VGQGGFGRTYLAEDINRFRELCILKEFSPQVQTAYVLQKAEELFQREAKV
LHQLQHPQIPRFREIFRVNLAGKEYLFLVQDYVEGETYSGLLNQRIQQGL
RFTEAEIRQLLQQILPVLDYIHSLGVIHRDISPDNLILRSVDKLPVLIDF
GGVKQVVAVVASQYYQPGVVASPPAATLLGKVGFAPPEQMQTGNVSPHSD
LYALAVTAVVLLTGKQPQELLDTYNLSWNWRREISLSPIFGQVLDKMLAA
RPGDRYQSAQQILHALNPAPVNYPPTQPPIPTPLPTPPPVSTPDTIAVAP
SLPTPDISPAPQRKNWLIPTAAFLLVGTVGLVWLGMSNSDRNSISVDPTP
TPTETQPTNPLDKYSPAERQRKQTLNDRRQQLGIDFNFYINVVNQIFWDR
NPSERGRTLSDGAEDENLRTEWDAVAAELLDKLKPLSNRARRQLGTYTAA
ERDRWKVEVNQINVGSRSLYDLGDAAFFRAFPEQKGKNFIEQPIGQVWQA
FVSDKLSAIVAGTVFQKIVFDPGATSKTVSGTLQPAGGRVFIADLAQNQS
LELQLQANSKVLLSVYSPSGKTIFLEDSEKRSLSTELPESGFYEFVVVST
ASTSADYQLTLTVENPTPPPEPTPTPSETTTPTPTPSETPTETPTPTPTT
AP
>Ava_0085 possible sensor with HAMP domain
MLKKIKIGTKFNLLLTIVFIISIVVSGAALSSILQNRAQTEVISKALVLL
NTMTSVRQYTQDRVRNLLLPQLETEAAFIPETVPAFSATEVFENLRKNEQ
YQNFFYKEATLNPTNLRDKADTYEAAIVERFRKNPSLPEIASFRTLPEGT
VFYIARPLAIKEQSCLQCHSTPEKAPKSQLVTYGSENGFGWQLNEIVAAQ
IISVPSEEVFNNAQSTWLGIMAFLVVIFAIVVIIINFLIKKTVIQRIRKI
ENIAQRVSTGDMSAEFEDKTNDEIGGLAAAFNRMKYSLTIAMDMLNKQNE
>Ava_4702 Response Regulator Receiver Signal Transduction Histidine Kinase
MNLPSILVIDDLPDNFDVIETLLSEQDYTLHYVASGQEAIASLNLFQPDL
ILLDVMMPGMDGIEVCQRIKAMPQWQSVPIIMVTALTAKEDLARCLKSGA
DDFISKPINALELRARLHSMLRIKQQYDKIQTLSNIQTSTIKVLESTLDE
LRGNLAAALPHELNTPLNGIVGTISILMADIENMDTGEIQELLGWVDLSA
RNLERLIKQLLLYLELELSTNQQQNIASESTHFSIAVIEAILQSHAPSVN
RRDDLMFAIEEAEVSISARYLAIIIYELVDNALKFSRRGTTIKISSQVVA
GMLNVYIHDFGRGMTEEQISKIGAFMQFERKTYEQQGIGMGLKLAKQIIE
SHGGLFSISSVYKKETMVHIALPIAYSRYLS
>Ava_B0009 Serine/Threonine protein kinase with TPR repeats
MSVYCINPLCEQRKNPDNAEVCLACGTPLIINNRIRLLKPLRELSFDPQN
YFEVFEVEDRRTQEYPVHQRRVMKVLKWNSSKYRELIEQEFLTLQLIKYP
NIPKCNINDFFTFTPHNSPLELRCLLMDKIEGKNLDDWIKSHDKITQNLA
WEWTKQLVEILDVIHHNEFFHRDIKPANIILQPNGQLALVDFGTARRITD
TYLAKISASGGTDTTIGNYEVTTVISPLYSPLEQINGRAVPQSDFYALGR
TIVRLVTGVSLLQLPTDKKTGKLIWRNKAPQIDKPFADFLDELMSPLPGK
RPQSTKIILERLENLPWHSQVHRIISSHIFKISIVSIFLLVSLASYIFLQ
PVIAESFLNQGKKALEQNQLDEAQNKFQQAVKIKPDIAKQVSNFYLEQGI
RRDISPQRARQYYELSIKYNPQNGSAYNNLALICQQLQDIECVNNSYKEV
FKLKPNKWESHYGLGSFYDELGKYDLAEQQYNLAIKSSDLALDAVSNLAR
IKVIQGQYEAAINIANKGLQKAEEPELKAALYKTIGWAKYEEKKYAEAEK
NLEKAQSLDLQRVDTYCLLAKTQEALGKFESARVWWEPCLLISTNLPEVV
QWRVEILQRIQLPRNYETKK
>Ava_1003 Multi-sensor Signal Transduction Histidine Kinase
MNINDITIPFHVDLSNCNKEPIHIPGLIQPHGVLLALQEIDLTILQVSNN
TFNLLGRHPEQLLNQHLSCLLEAEQINLLQDCLTQEDLQIINPLEFIIKS
HNQSINFDVIAHRSNGLLILELEANLSDKNYSFFRFYHLVKLAMLKLQGA
ATTTEISQILAQEVRKITGFDRVMVYRFDEQWNGKVIAEVRPEYLTSYLG
LHYPASDIPQQARKLYSQNWLRLIPDAKYQPVPIVPTNHPLNNQPLDLSR
SVLRSVSPLHIEYMQNMGVTASMSISIMKNQKLWGLIACHHQSPKYIPYE
IRSACEFLGQMTSVEMSAKEDSEDTEDKIRVKSVHSKLVQYMSAENDFIN
ALIDHQPNILDLVNAQGAAVCFNGNFRTVGQVPPIPDIQVLVEWMSQNIH
EEIFATDSLATVYPDAEKLREVASGLIALSISRSQKNYVLWFRPEVVRTV
DWGGNPHKPVEVIANGGIRLSPRKSFELWKETVLLKSHPWKSYEVNAALE
LRSAIIGIVLQKADELAQLNIELKRSNQELDAFAYIASHDLKEPLRGIHN
YSNFLMEDYGEIIDAQGKEKLLTLIRLTQRMEDLIDSLLHFSRLGRVDLS
MQDTDLNEIVHRILDMLSGRIEETGVEIRIVQLLPVVYCDRIQIGEVFSN
LIANSIKYNDKANKWIEIGYIDNQPLPPTFYVRDNGIGIREKHFEAIFRI
FKRLHSPNKYGGGTGAGLTIAKKIVERHGGKIWVESTYGEGSTFYFTLQG
V
>Ava_2691 conserved hypothetical protein
MKKFINWLKNVRPLKIATVFVLGFFLLFTQSCSAKGIAAQPPQQKAESAY
IERYDPTKEYPLNAPKGGMNNFSDVDPRAEVGEKTAETKAKALRDNAKRN
VDEKGIDSTEQYARNYRQGTPFGERVKNLGEDIGSSAEELREGVVKGTQR
GLENIKENTQNAGEDLVKKGKQTTGND
>Ava_1560 Response regulator receiver domain protein (CheY)
MQERVINILLVEDDEVDVMNVKRAFQKVNITNPIYLADNGLEALKILRGN
HTQTPNFPHERRLILLDLNMPKMGGIEFLQELRSDPQLRLTPVVVMTTSN
QDKDRVEAYNLNVAGYILKPVTFSSFVEIIAALNKYWVFCEMP
>Ava_1498 Two component Transcriptional regulator, Winged helix family
MPRILVIDDDPAISELVAVNLEMAGYDVSQAEDGIKGQALALQLQPDLIM
LDLMLPRVDGFTVCQRLRRDERTAEIPVLMLTALSQTQDKVEGFNAGADD
YLTKPFEVEEMLARVRALLRRTDRIPQAAKHSEILNYGPLTLVPERFEAI
WFGQTVKLTHLEFELLHCLLQRHGQTVSPSEILREVWGYDPDDDIETIRV
HIRHLRTKLEPDPRHPRYIKTVYGAGYCLELPSVPQSGEGATTSVVE
>Ava_3043 Multi-sensor Hybrid Histidine Kinase
MKIDELTMPFNELPIDLHNLYHLIDRHPLTIAPDSYVIDAIRLMNQQGNS
PPFISLNSSGTYSNKNSKQTSYVLVVEAGNILGIFTERDLVRLAASKFDL
SDLKISEVMTQPVITMKMSNSPDIFTALSLLNHHQIRHLPVLNSREQLIG
VVSATSLLQGLHQLESFYCLQSLQQAQQIEFLRYPSRNPLNEVEHHDEFL
GLRKVCQRGIVEVQRAEQALQQSEELYRQLVELQNEVILRVDNLGRLTFV
NSVACKIFGKPMDELIGQLIFEWMFPEDEIPQAKEYFQALKSPPYQISIS
EQPVLTPSGIRWFQWNIIGIENTIGEVVEFQGVGRDITERRQAEESLRQS
EARLNLALEAANMGIWDWYLLTNETIWSANMGLLYGLPSTTLCPSPEDFL
QLVHPEDREKFSQSAKNSIEQGIPFTIEYRTVWNDGSIHWLNSKGQVYYD
KAGKPIRMIGTTRDISERKQAEASLRESEELYRSVVTAMSEGIVLLHTDG
QIIACNASAERILGLSREQILERTCVDERWLTIHEDGSPFPREQHPAMET
LRTGKPCSNVVMGVHKPDGQISWISINSQPLCRENETVPYAVVTSFADIS
EQQAALRSRQQAEQKIREQAALLEIATDAIFVRDLQSNILFWNQGAERLY
GWSQQEAIGRNTQELLYSETSFHLHEAALNVVMELGLWQGELQKLTKSGK
EVIVESRWTLMRDAAGQPKSILVVDTDITQKKQLEEQFFRAQRLESLGTL
AGGIAHDLNNILTPILAASQLLKVKFPDEQGRTPMVGSTSFQHLLEIVES
NARRGAGLVKQVLSFARGFKGERTIVQLKHLITDIILIGKQTFPKSIEFI
SSFPEALWSVCGDVTQLHQVLMNLVVNARDAMPNGGKINVTAENIFIDET
YASMILEAQVGNYIQLTVTDTGIGMPPEILNRIFEPFFTTKEVGAGTGLG
LSTVLGIIKSHGGFVKVSSKVGQGSQFKLFLPAIPATPDLTIEEIETPSG
SGELILVVDDEAPICEIAKVILEKFNYKILTACNGIEAIALYAQHKHRIS
AVLMDMMMPEMDGITAIRTLKKMNSKVQVIASSGINSTETVAQAAMIGVQ
QVLPKPFTAKELLNSLHHVLRC
>Ava_4489 Serine/Threonine protein kinase and Signal Transduction Histidine Kinase (STHK) with GAF sensor
MLRLVGYQNLTQIYAGTRTLIYRGIREEDQKPIVLKILRYEYPSFSELVQ
FRNQYTITKNLHIPGIIQTYSLENYENSYALVMEDFGGISLKDWSNQNSE
ISLDEFFHIAIQIVTILDGLYRSRVIHKDIKPSNILINPITKEIRLIDFG
IASLLPRETQTLTSPNVLEGTLAYLSPEQTGRMNRGIDYRSDFYSLGVTF
FELLTGQLPFCCDEPMKLLHCHIAKHPPQVHEINFTIPLAVSNIVFKLMA
KNAEDRYQSALGLKHDLETCWRQWKTQGEISAFELGRRDICDRFIIPEKL
YGRQAEVQQLLATFERVSQGHREMILVAGFSGIGKTAIVNEIHKPIVKQS
GYFIKGKYDQFQRNIPLSAIVQSFQDLMGQLLGEANTQIQDWKTRILAAL
GEQGQVIIDVIPELQSIIGQQRQVTELEPSAAQNRFNTLFLKFIQVFTTK
EHPLVIFLDDLQWADSASLKLIQLLMSQRDNHYLLLIGAYRDNEVSSGHP
LILTLQDIQKNTEIIETITLKPLELLDLNYLVADTLKCDKEVALPLTQLV
YQKTQGNPFFSNQFLKYLYNENLISFNFDKGFWECNIAQVKTLSLTDDVV
DFMSLQLQKLPEATQNVLKLAACINNHFNLSVLANIYETSLAETAAALWT
ALREGLIIPTNKVYKFFHDDLSLNNSYNLNNNIEPITVEYKFLHDRVQQA
AYSLIPEDNKKLTHLKIGQLMLANSTPETREDKIFEIVNQFNIGVDLITE
APARHELAQLNLQAGTKAKSATAYSAAIEYINLGIGLLTANRWESQYRLT
LTLYSEAVEIAYLSTEFQRMETLAQTVLKNAKILLDKINIYSIKIQACIA
QNQLLLGIETALPVLQMLGVHLPPKPTQTDIVKSLQDANSVLMGNTTSDL
INLPKMDNPEKLAALSILSSMFGAAYNGYPAMFPPLICEEVILSVKYGNA
PVSAFAYASYGAILLTFMGDIDAGYEFGNLALNLIAKLDAKELKAKTFCV
VSCLIKHWKKHLRYTFPLFIEGYHSGWETGDLEWSAWCAFSYTLYLYLAG
TELYSLEQEMSIYSQAIAQFKQKTSLNYLNIYYQSVSCLLGVTENHLQIK
GNIYDEAVMLSIHEQASDRPAIYHLYINKLILCYLFCEYEQAIKNAEIAE
QYLDGVLGIYVVVLLPFYDSLARLALYPHTTVDIQQKILHRVSENQAKIK
QWADYAPMNHQHKFYLVAAEQNRVLGKYLEAMNEYDLAITKAKENKYLQE
EALANELAAKFYWELGKEKIAQVYFTDAYYAYTRWGSIAKVKDLEQRYSQ
LFSLLSRRSNLIFNPNDTIVKHDSNSSHIHQTQHNTHYYSTTNSNVLDLS
SVIKASQALASEIKLDKLLSALMELVIENAGAKKCVLVLLKNEKLVIEAI
ASINQIPISTILVSIPIAESDEIPISLINYVSHTSQTLVIDDATIEDSFI
SDPYIQKKEPKSLLCTPIIKQGKLMGILYLENHLTTGAFTSDRLQVINLL
MAQAAISLENAQLYGQLAEYSQNLELKVEQRTQELKEKANQLESALQKLS
STQSQLVQAEKMSSLGQLVAGIAHEINNPVSFIYGNLTYTSEYINSLLDL
INLYQQLYSQPLPEIQQRISDIELDFITEDLPKMLKSMRFGAQRIEEIVS
SLRTFARLDEAGMKRVDIHSGIDSTLLILQHRLKFKQNRQSLPIAVKQNY
GNIPQIYCYASELNQVFISILSNAIDALQEDVSNQSGREKQPTITISTEV
KNAESILIRIADNGPGMSDSVLSKIFDPFFTTKPVGSGTGLGLSISYAIV
VEKHGGQLLCSSGPGMGTEFTIVIPIQTFDTAISRETTNTNSKLRKCDSA
>Ava_0238 Multi-component Transcriptional regulator, Winged helix family
MKILIVEDDELNAYALTAVLTNQNYAVEVGSDGITAWELIQTYDYDLILL
DVILPRLDGISLCRQIRSSGRQMPILLLTGCDSSHEKAIGLDAGADDYVV
KPFDEEELVARVRALLRRGGTTAQPILEWGNLQLDPSSCEVRYNQNLLSL
TPKEYALLELFLRHSRRVFSCSMILEHIWSYEDTPGEEAVRTHIKGLRMK
LRNAGAPGDLVETVYGIGYRLKAQEEEQGSKDEVKHSQSTSKGKSQQQTL
TAIAGIWQKFYGRVDEQVKVLEQAAMTSDRPEIVTLTQETLNPELRSQAI
REAHTLAGSLGTFGLPEGSKLARKIEQLLKSGKKLTPTEIQSLQNWVKLL
RQEVAAHEPQAASPETTSAAILQLQPPQAEAKVLAVDDDPQILAILQTLL
HPWGLQVITLDDPRQFWETLRDVNPDLLILDVEMPYTNGIELCQVVRNDP
QWSELPILFLTVHKDGEIVNQVFSVGADDFVSKPIVGPELVTRIINRLER
VKLLHKVSESRGIGEKNSPPSPSFTDWRTIFNAEPECVTIVATDGTLLDI
NPAGVAAIEADSAGAVIGKRVYSLVVPEYQQVFRQLNESVCQGEQGTLEF
EIITCRGNRRWMATHAVPVRNETDGNLVQLSITRDVTQYKQAELEIKRIN
RTLQTLSDCNQLVIRTQDEGELLQKVCQILVDVGNYRLAWVAFAENDAEK
SIHPVAQAGYEQGYLQSLNLTWADTIRGQGPTGTAIRTGKTAIIQNILTD
PRFEIWRCQASNRGYASSISLPLMNNGQAFGALNIYAAEANAFDSDEVKL
LEELTADVAYGIVALRNRRDRQIAEAALRESQERLALTLEAVNLGIWDWN
ITTNQIIWSEGHARLFGIESEKFDGTYEAFQACIYPEDRGGLAEVINSAR
QQKTDYSHEFRIISPDGNIHWIEGTGKLYYNEMGEAVRMLGIVRDITSRK
QIEATLQKVNNELELRVAERTAELVNVNRQLQSELDERQRVEEALRISQV
RLARILDIADDAIISINGNQQITLFNQGAEKIFGYSAEAIIGQRLDTLIP
QRFTQAHRQHVADFGQAPNLARRMGERREIFGRRQDGTEFPAEASISKFQ
LDKEVFYTVILRDITERKQIERMKDEFVSVVSHELRTPLTSIHGSLGMLA
SGLLPADSEQGRRLLEIATDSTERLVRLINDILDIERIESGRVKMERESC
NLTDLIESAVSIMRPLANKAGVKLSVSHPSIQLWVDPDRIVQTLTNLLSN
AIKFSTAEKTVWLVAQQYGDELLVTVKDNGRGIPADKLDSIFERFQQVDS
SDSRNHDGTGLGLAICQSIVQQHGGRIWAESVLSEGSNFYFTLPILPISP
NSELPDSLTHYPLSPEGDLPSPIPSTHSPLVLVCDDDPLIRTELQSLLEQ
GGYRVVTVATGKEAIASASTQHPDVIVLDLLMPGMNGWETMAMLKESTET
KHIPIVICSVYKPTTNNQPSSDFVDWISKPVQESYLLHSLRQAIAKSSRR
VRILIVEDDADLAELFVTLFERHDIETFSAKTGREAIHLSQEVNPDLLIL
DLILPETDGFAVVDWLQKHQRLCNIPVVVYSAKDLDESERKRLKLGHTEF
LTKGRVTTKEFEQRVIELLQRITPTNVRD
>Ava_1628 Multi-sensor Signal Transduction Histidine Kinase
MRLSNLFRKRSANNEKLKISLQFILTVPFVLLIGGTTGLVSYVSWQNSQN
SVNSLAYQLMNEMSDRIHLYLSNYLKTPHLINRLNVQASTLQHIDVTNPQ
SLERYFFAQVQEFASLRVHFINPQGGLIGAGNDERGVTISSTKDFKKGEL
YVYSVDSQRKRKKLLVHQHNYDGTQRPFYQQALSTGKPTWTSVYLYVPTS
RGLGIAASYPLYNQRQELLGVFTSDIDLVSISKFLQQLRVGTHGQVFIME
RSGLMVASSTPEQPFLTGMGGTQNQRLQVIQSQQPLIRLAGEHLRSHFGN
LAQIQTAKQLNFDIKGKKQFLLVIPYNDQLGLDWLIVTVIPASDFTAEID
ANTRLTIIFTIGALAGAIALGLFLTQFIIRSMEQLGQTSLALYNELHLRK
IAELELRRQKDLCESIYNESADALFLVDPQTLLIADCNRRAVELFEADSK
SELISIKVNTLQLQPFTSDELAQITTQIQQKGVWNTEIQYLTRKGNLFWG
NLAAKEVTMVCDRPSVITNQVVYLVRVTDITERKRAETALLQSEARFQKI
AAASPAQIYILAYYPDINQMRYEYISSGVQEIQELEPHQVLADPLLTYQQ
VHPDDLALYNQLTTRSLKTLKPFAHEWRIITPSGKVKWVRANSRPERRSN
GEIAWYGVVLDITDLKQAEAALRESEERFRHAFYDAPIGMALLGLEDQQW
LQANPMLREMLGYSELEFFSFQAFEIIHPEDIHRLENCITQVLSNQNPRV
QVELRYLCNGGRIAWGLTSLSLVRDCQNQPLYYVLQIQDITEQQAIEQIK
NEFISIVSHELRTPLTAIQGFLGLLNTGIYDNKSQKAKWMIQQALTNSDR
LVRLVNDILDLERLSSGRVQLVKEVCHAADLMQRAVEGVQSIALASAITI
SLTPTTACVWASPDLIIQTLINLLSNAIKFSPHNSVITLSAQPQSDWVLF
KVQDQGRGIPANKLETIFERFQQVDISDARAKGGTGLGLAICQSIIQQHD
GSIWAESTLGEGSTFYFTLPISVKEL
>Ava_1944 Two component Transcriptional regulator, Winged helix family
MDILIVEDESEIAQLIQHSLEKEGFSCRTSRDGINALRMFQEQPPDLIIL
DLMIPGLDGLEVCARIRQKPGAKDPYILMLTAKGEEIDRVIGLSTGADDY
MVKPFSPRELVARVRALLRRSLRQGGQNQVSRTQHFIVDVDQRTASRQID
AHQAEALDLTTLEFNLLSTFVSNPGRVWNRTQLIDKLWGDNFFGDERVVD
THVARLRKKIEPDPTNPSFIKTVVGVGYKFEDSPVISA
>Ava_0089 Sodium/hydrogen exchanger
MLFSILWILIMGFFAGQLARRLTAPPLIGMILVGIILGPQVRNLISQDVL
GAADELRTVAVTIILMKAGLGLDREKLAQQGSVALRLGFLPATTEAIAIA
IASIIIFKFDFPTGLLLGCVIGAESPAVIVPGMLRLKSLGLGVTKGIPDA
ILTGSALSDVLLLLVFSLLLNFLSDGGVEQITLIGGFTLNAVYLLPIQIL
MQIVLGLFLGYLAARLLVLLLTKQNWTQNAVQDTVIAASLALFLVIIANT
LPYFSGYLATMAMGFFLIELDAPLARRLRGGFDSLWVVAEIFLFVLLGAT
IQLQVLENILLPGILILSIGLFIGRMIGWYLSTLGSNWNWHERLFLLPGN
SAKATVQAAIGAIPLAQGIAGGEIILAIAVLSILITAPLGAWATTVFAPK
LLRRGEVDPTKVTIATRTLLLAAVDTSSLAIEVLTKVADLARRSNGEAIV
LHVVNTSNQQDVEQIQAQAKQLLSDIRYKFLTITGAVPEEILRIAETYNA
TAIVMGKRGHQPWEKVLIGSVSQAVIENSSIPVILLDTRPKKN
>Ava_1168 Multi-sensor Signal Transduction Histidine Kinase
MLSSPDLSFSRNLPLVVFNQLGELLQQMAQSVETSTLLLTESLLSRVFVP
MEWHSQRFTLVVSEGFSALLLGNWEQQELPESENWILAMPSPLNQGIAGD
RETQKQEIYSASSIPQAAQSPLTLTELNTRLTFNSEAIASFLAKLRDLFG
DDSPTHQHLERYRQILKPNDATRQSQFTLLLLEHLLPKNNEEVTASASVN
NSEEVYACQAVEDALKKQISQERLLNQVTTQIRKSLDLPVIMATAIAQVR
EFLELDRLVIYKFEGSRVNTQNTRPPRLEDWQNYGGCIVYEARATDIIPS
VLDYQEKTCFSRHSQCWEKYRQGFTLVIDDIEQAYALEECLVNFLRENQV
RAKLAAPIIFEDKLWGLLIAHQCHSPRQWNDSDKNLLISIAEQLAIAIHQ
SELMRSLQDAAHRLTQEKHTLEQRVIERTMALRDALLAAEAASRLRSEFL
ATISHELLTPLTYVIGMSSTLLRWPLGELSQRQRDYLQTIHDSGEHLLDM
INDILDLSQIEAGKTVLNIAEFSLIKVAENTIESLVEKALSEKVNLKLDL
QIDPRRDRFTADAARIEQILWNLLTNAIKFTPEGGNVTLRVWVEEDTSIF
QVEDTGIGIPEEQLPLLFEKFQQLDTPYRRRYEGTGLGLALTKQLVELHR
GRIEVESTVGIGSIFTVWIPYQEIRE
>Ava_2109 Serine/Threonine protein kinase with Chase2 sensor
MAEEPTEKVNKKNGSTANIASNKTTKATLTAAARQSQRLVRLGNILTVAL
TMGAALLTTSGLSLVQLLENQAISAFFQIRGPLIPPEDIVILAIDDQSIS
VPEQYYRTYPQKYAYLEPLSKFPFKRVAYAQVVEKLMQAGAKSVALDVVF
DLPGSYGNEDDRQLQAVLQKYSGKVTLAAQYETSQSHQGFFTQLRLPYEK
FRNDEASIGTVNFPVEVDGKIHRLGSELTKILGEVDALTDKIPSFDQAVL
ATAKVKYPRSPGERIYFWGPAGTFATIPFWHVLDPQNWNTYLQQGQVFQN
KIVIIGATAQLANDYHAVAVSSAWLSSEKMSGVEIHANAIATLMEGKAIA
QGIPSQSLQALFVLVLVGGTSFIITRSKSGLQRFILSLAVASGWGSISYI
SFVYAQLLFPTAIPMLAIAFCGISYLGTEVAKEKIRTRQIVDIFQKYKTS
PVVQEIISQQQELQDLLQQRNVAVSGKILSGRYKILKVLGYGGFSETYIA
EDTQRPGNPQCVVKQLKPVNTQAKGLQLARRLFNLEAQSLEKLGSYQQIP
QLLAYFEQEAEFYLVQEYIIGHPLNQELPSGKSISEAETVAIIREILEIL
VFVHENGVIHRDIKPSNIIRRHSDHKLVLIDFGAVKEISLPQANNQEPLP
FTIGIGTKGYAPSEQCFGRPQYNSDIYAVGMIGIKALTGIAPHDLPRDEN
EEIKWRDKALVSQGFAQILSKMVREDFKQRYQSASAVLAALNKLANTPDK
NFGQQNDSSMNTIISIDESDFPTAHWP
>Ava_3777 CheW protein
MESQQKFLSFNLGIKDTAVISLQHITEVLQVSLVDICGVPQMPACVMGVY
NWRGEMLWLVDLEEMLGYPPLSHTSNFLAKMMAIVLEDDGKHLGIIVRQM
MDIEFLDNNQMKAPAAELFSSSITDFLQGYFINHDEKMMFNLDASAIIHS
PMWVTHN
>Ava_0972 Cyclic nucleotide-binding domain (cNMP-BD) protein
MLNPVVTIAIFQKQPNPQVFSAGQVIFEEGQAGDYMYGIVKGAVDLLING
KVIETIEAGEIFGTGILVGVNHRNYTAIAQTDCQLAYLDEKRFLFAVQET
PMFALNVLRNYSERLSRLQRLV
>Ava_4216 FHA domain containing protein
MIVCPNCNHPNPDGAVQCEACYTPLPATSNCPNCGATVQSDAAFCGQCGF
NLHSVAAPAATVATVAPDVPVELPPLANPDPLLELLQPNALGLDPVANET
PPAPAPLPPTAVAAPPSAPPVVVEVTPAPPPAPVEASIPTPPPEPVAPPE
PVPAVEAPAPAPETVVAAPPSPARTQLQQITARLVHVQSDREIELPPSLS
VVHIGKPNDRIPPDVDVSGFANSEIVSRVHADIRLEGDAHYIEDVGSSNG
TYINNLPLLPGNRHRLRPGDRISLGKGDLVTFLFKLA
>Ava_4344 Response regulator receiver domain protein (CheY)
MTTAIMPIEVLLVEDNPGDVELTRIALEDSKISVHLSVVEDGVEAMAFLR
KQDKYANVPHPDIVLLDFNLPRKDGREVLAEIKTDSYLKRIPVVVLTTSQ
AEEDILKAYNLAANCYITKPVDFDQFVRIVQSIENFWFAIVKLPPE
>Ava_0762 Serine/Threonine protein kinase
MAWVSGQQLQGGKYTIEQELGEGGFGITYRARDNYGRSVVIKTLNDQVQR
HSDFAKFQQDFLNEAIKLAKCSHPHIVQIHEVINEDSLWCIVMQYIDGEN
LASRVENQGVLPEAEALRYIHQIGEALTVVHNNGLLHRDIKPQNIMLRSG
KSEAVLIDFGIARQFSPNLTQKHTEYLSSGFAPIEQYEERAKRGAYTDVY
ALAATLYSLVTGEVPTMAPLRAIGTSLVEPKNISSHISDQVNQAILRGME
VKPENRPQSIQEWLALILLENNPANFPEMLGTWLGKFGSGQATLSITHQK
EDYFDGTLIHKHFWNGTAKVAIEGNVNHETNIVEIKEIRIISGYWRLAEN
QGSLSSDGKTISGIGKDSQGSYKWALQRIV
>Ava_0124 Response Regulator Receiver Signal Transduction Histidine Kinase
MNLNNNNKYKGNILVVDDTPDNLRLLSAMLTAQGFEVRKALNGKMALTAC
QMLLPDVILLDVNMPEMDGYQVCQQLKDDEHTSDIPVIFISALDDVLDKV
KAFDVGGVDYITKPFHGAEVILRIENQINLRLLQLQLQERNLLLQDALNN
LKASQVQQIQNEKMVALGQLVAGIAHEVNNPISFIYGNLQYANEYIQDLV
KIIEVYQQEYPNPTPKIQQLIQKTDLNFVMQDLQNLMGAMYRGSDRIREI
VLALQNFSRHDEAEMKLVDIHQGIDSTLVMLQHRLNATSNRPAIDVVKDY
SNLPLITCYPSELNQVFMHILNNAIDALEVREETDSGVIPMTPRLRLQSS
QVNPLWVSVRQGTSHLQSLGITKIKEELPNQNPQIRISTELLDSHTVRIA
IADNGVGIDQSWQSHLFDPFFTTKTVGKGSGLGLSISYQIVVQKHQGQIT
CASALGEGAEFVITIPITPA
>Ava_4670 Response regulator receiver domain protein (CheY)
MRSPKRLQYWYLTIVTLPFYFCSIMTHILLVEDEVKLARFLELELNYQGY
QVSVAYDGLTAMIAAGQLQLDLIILDWKIPGLSAWEICHRLRNSAKNIPI
ILLTVKDEVTARIAGLDASAADYVVKPFNIEELLAKVCSHLRKTQQADAA
DK
>Ava_3908 Predicted periplasmic ligand-binding sensor protein
MTGGAVSKGNVIVGLFRKRISLLITSILLGSISLPSMNVVGIGSLARAEK
AATNAPSPTTPDIKPSELKPAYPPSAPPPRVDPLPDERDIQERAVEIDYR
VSNLLGDFAGNLWVGSWRGLSRIDPKTGKILARVSLPNVAIGALAQDKVG
RLWVGTYEGLMRVEPRTNEISAQNLFLPSKRVLSLLTDKRGYLWVGTDNG
LALVSPDQGLIMTTVKNLPGVSGNTLTLDADGQLWAGTLDGVVRINTASA
LIMKRINDLPGTTVQALAISPEGLIWAGMPNNLLVINPKTGIVLRSVARL
RGKNVTAVRFAKDGSVWVGTHNGLLRLNPNTGAVLDEVAGLPSSRVLSLV
PDVANKLWIGTSEGLAWLMPKMDKATAHLAFSRLVK
>Ava_4267 Multi-sensor Signal Transduction Histidine Kinase
MSPIAKPNSQVSLNQESVVRRITARIRQSLELEDIITATTAEVRTLLGTD
RVMMYKFHADGSGQVIAESIYENRLPSLLGLNFPADDIPPHARELLVKSK
VRSIVNVTTGMIGQSPVHNLETGELISEDICYRPVDPCHLEYLTAMGVKS
SVVAPIFHQDELWGLLVSHHSENRTVSEDELEAMQMIVDQLAVAIAQSHL
LTQARKKAQKEAIINRIITLLHSLPTIVLQPTLEAAVAAFDGVGGRLCLR
NQAVESQHVASRSLAECLIPGNNCVQLYTCGQQPITPEQTIYPLIEQYRV
WQEHYTSHHDIWAIADIYQDPTLRSLQAVFQTTKIRSILIIPLEYRQQLL
GYLTIFRNEIDTETLWAGHIDQDQRQMFPRVSFNLWRDAKKSQAQQWTSE
EIELAKEIGQHFASAIQQYELYQQVQAFNENLEKQVQKRTLELRHTSEQQ
QAVFGVISKIRESLDTNTIFQITTKEACQLIKADRVSVYRFDDEWGGEFV
GDFEATSLHWSNESSISINTVWNDTYLQNTQGGRYRYNETFAVDDIYKVG
FTQCHVENLEQFQIYAFVLAPIFVGQKLWGLLATYQHSGPRQWKPSEVNF
LTQIAAQLGVALQQAELLNQTQQQAQKLTQTLHHLQQTQTQLIQTEKMSS
LGQLVAGVAHEINNPVNFIYGNLSHVSEYAQNLLTMLELYQQELPNPSAA
ILEQADEIDLEFLAEDLPKTLSSMQIGVERIRQIVMSLRTFSRLDEAEMK
AVNIHEGIDSTLLILQHRLKAKPETAGIKLTKKYADIPLVECYAGQMNQV
FMNVLSNAIDALEDYKEAQSKNHHGEIIIFTSFGQIRDNIQSVVIRIVDN
GPGIPEDLRLRICDPFFTTKPVGKGTGLGLSISYKIVVEKHGGVFKCDSQ
LGSGTEFWIEIPIQQVNNNW
>Ava_3771 Multi-sensor Hybrid Histidine Kinase
MSVLNMNHDEYNQESLKNVNKQAQEALQQQIERQRLVMAIAVRIRESLRL
NEVLNTTVAEVRQFLQADRVFIYRFAPNYSGCVVVESVGDNWRAVLNAQV
EDTYFMETHGEKYRQGGLQAIADIYAEDISECHRDLLIQFQVKANLVVPI
LQGEKLWGLLVTNQCGTSRHWQSWEIDLLQQLATQVGIAIQQSELYEQVR
AELKERKQAEQKVREQAALLDIATDAILVRDFHSQILFWNKAAERLYGWQ
AHEAIGKNSEELLFKESSSQLELVRNHVLEHGSWQGELNKITKSGKEIIV
ESRWNLMFDESGQPKSILTVDTDITEKKQLQAQFLRAQRMESLGTLASGI
AHDLNNILTPIMASIQLLALKSSSNDARNHQLLKILEHNSKRAADLVKQI
LTFARGSETRGVTLQIEPLLLEIEQILNSTFPKSIKITKHLPPENLWTIQ
ADPTQIHQVLMNLCVNARDAMPGNGTLSIFAENLLVDKNFAKMNLDAEVG
PYVVITIADTGFGIPPLILERIFEPFFTTKESGKGTGLGLSTVIGIVKNH
GGFVNVNSEIGKGSQFQVFLPAVEDRAKQQVEDLDLPAGQGELILIVDDE
AAIVEITKTSLEDYNYKTLTAKNGIEAIALYAQHQDKISMVLMDIMMPSM
DGLTAIRILQEMNPQLKIIAISGITGNNQLAEAANAGVNAFLRKPYNIYD
LVHAIHNIFHQVTQ
>Ava_0060 CheW protein
MDNSQILMATLLPQNKSGDGYLKFYLNQQSAAILAMNHTQEAVLISAESI
TPMPNMPHCVLGLMNWRSRIIWVIDLPKMLNLESLENRVHQYSVIVIKVE
STILGLVVQEIKGITKFMSDEIRSPIGQVASSLVPYLRGCVTQQEENFLV
LDAQAIVNSSVLIGNQNYQ
>Ava_0064 Signal Transduction Histidine Kinase
MNQRFPLTILLIDDCAEDREIYRFFLQQDRLHTYEIFQLETAQEAMTWCE
QQTPDVILLDYLLPDYDGLEFLQQLREHLNNSQSAVIMLTGQGDESIAVC
AMKNGAQDYLVKNSLTPETLQSAIHYAVERMLLTRQLEQSRQQQQLMVAI
ALRIRQSLKLEDILSVTVAEVRQFLQADRVLIYQFQPDMSGIVVAESILP
GWIATKGAQIEDRCFQDSAGHNHQVKKRAINDVYQAGLTNCYLELLEQFQ
VKATLIVPIMVTNQSWGLLIAHQCAAPHQWQSFELDLLEQLAVQIAIAIQ
QASAYAQIQTELQERKRVEATLRESEQRFRQMADTAPVLIWMSGLDKLCY
YFNKTWLDFTGKTLEQEVGDGWAKGVHPDDLKDCLDIYVNAFDTRQNFQM
EYRLKRFDGEYCWILDTGTPRFTTEGEFLGYIGSCVDISERKQVEAALQQ
NEERLTMALDAACMGNWEWNIQTGGIHWSENLEKLFGMVPGSFNGHFETV
VSLIHPDDRQRVLQSINCAVYNREDFNIEFRFIKLDGTPRWALSRGKVFY
DRNGNPLRMSGIDFDITERKQAESKLQESEGRFQAFMNNSPSASWITDDH
GRILYLSQTYVRTFQLPFDKVENVMGKTVFELYAPEIAQQFLDNIHQVAQ
TQQILETIEKAPRLDGTLGDFLVYKFPLPGTTGELLIGGVAVDISDKIRA
EQALQKLNQELEARVAERTAALRESEERWHLALRGSNDGIWDRNITTNEV
FFSIRWEEMLGCSSQELSRNRESWLSRIHPDDHDRIMRAIADHLAHKTPF
FQEEYRIQRKDGSYIWILDRGQALWDESGNAIRMSGSATDITKRKETENQ
LLNISRLQHAILSSIDYAVISTDSDGIIQTFNLAAQRMLGYTADEVIGKL
TPNSFHEPEELRQRMNELKQEMGREITPQDFMVKTQQDSDELEWTFIRKD
GSRFPVALSVKPMFNQEGKPIGGVGIAKNITQQKQIEAQLRKNTSTLAAA
QRIAHLGSWELDLSTHNLIWSQEVFRIFGRHPESGTPSYDEMLDCIHPDD
RNYRDVVLHQAITQRQAYELEYRFYRADGSLGYLLSRGEVILDTHGQPYQ
LISTILDITERKQTEERLRNLSDRLTLAVSSANLGIWDWDMIQEAEWDDR
MYELYNLQQSENKAKYQDWIDRLHPDDRDEAMMAFEDAIKGVREFDTEFR
IVLENGNIRFIKASALVQRNEWGEPLRMVGINYDITERKQVEAALRESEK
RYATLTEAAPVAIFRLDTASNCIYVNERWSLMTGRPTQAALKKGWLENIH
EEDRYHLVVDCAGLCGKQCGLSETCRREVRYVRPDGSITWFYIQIVPETD
LNGTILGYIGSLTDITTRKTIESEVIHHRDLREAIFNESADALFLVDRDT
QLIFDCNDRAVDLFEVANKEELLNIQGNTLQRYQFTPEQLDEITQELNQK
SWWSREIEYATRKGNFFWGNLAAKQITVAGKGINLVRLSDISEQQAAHRE
RKQAVEQIQRSLDEKETLLKEIHHRVKNNLQIISSLLRMQSRRSFDETTL
LLFTESQNRVQSMALIHEQLYQSADINQINFSDYIKNLTDSLFRCYGVSQ
KNIRINIETNSIKLDLDNAIPCGLIINELVSNCLKYAFPEQNEDNNITIS
LEAVPGNQLTLLVKDNGIGIPETLDWENANSLGLRIVKNLVRQLKGKILL
ECDRGTAFSIRFPQ
>Ava_1993 Metal dependent phosphohydrolase, HD region
MISERFTQALTYATQLHTHQVRKGSGIPYVAHLLGVASIALEYGANEDEA
IAALLHDAVEDQGGAETREEIRRRFGETVTAIVDGCTDADTMPKPPWKQR
KEAYIAHISTASPSVLLVSAADKLHNARSILQDYRLVGESLWERFQGGKT
GTLWYYRSLVDAYQKTETRAIFAELARVVTQIEDLASQKKSEA
>Ava_0354 Protein serine/threonine phosphatases
MLICPQCEFENPNANKFCQKCGASLSHKVCPQCSTEVPVNAENCHNCGAE
TGTVWRAIIETGDWAAAVSVSTLLSANPVDVASPKEDQTELGFEEDGEEK
IMLSPALFSVGSYLDKEQRYQILQVLSAAHDEVSVRVLDCQPYQVSPIEA
ILANQQQGLVTPAVEANGIPSLARAYMVLQSQNHTEIPRIHDAWEDGDNQ
ILLIEDRTHYQPLLDLWQKETTSSLEILHWFYQMTQLWVLLEPLKCHYSL
WDLANLCLDEDQTISLRKLYVKPPKSELAIDYLPLDFNPVTAQEEDVTLP
IFVQPSSIKALGEVWQALFRESQRTQFGSIIQILGDLQQGRIYSIAQLRS
RLQEVATELEATTPPIFEPMEAEQTNAPTVLQADDTEDPSGKGDDMPTVV
LSVQLSSLEDAGRTDVGRQRHHNEDYFGIETKTEKLELPRNRILQARGLY
ILCDGMGGHAGGEVASELAVITLRQYFQQHWTNNQLPTEEIIRESVYLAN
EAIYEKNQQEARSGVGRMGTTLVMLLVQGSQAAVAHVGDSRLYRVTRKRG
LEQVTVDHEVGQREIDRGVEASIAYARPDAYQLTQALGPRDETAINPDVE
FFDINEDSLLVLASDGLSDNDLLETNWQTHLLPLLSSSTNLEQGVTELID
LANQYNGHDNITAILVRAKVRPNLGEGTGD
>Ava_3542 PAS/PAC Sensor Signal Transduction Histidine Kinase
MIIVNCNSFAGTSKAQRVDETVKARHQQDQQQLINRLQATEAQYQAILNA
IPDFIFRLSRDGNFLSLNGEVANLPCPGEEFTGKNIQNVLPTDIATMIQG
IITKTLDTGTLQTCEYQLPTPLEIRDYEARLVVSGTDEVLAIVRDITERK
QTEAKLLLTYQELADLNTNLEHQVEERTAELQQKMRELEEIQRIKNVVLH
TVAHDLRTSVIGNLMVLENLGMGSGEWNVGSRENRGNSEHELEESTIPNP
QSPVPNPQSPVPSTQSPIPNPQPLISVPRSTIDRMIQGNNRQLGMLDSLL
EIHSCEEKELTLHRELVPFGGLLEKIITDLQPLLRENQATCKNLLPKDLP
LVMVDQVRFEKVVMSLFSYSLQHNPPGLEFTVKTTVEDGMIRTLIQDNGI
TMSKSECDRLFDLQIRDPQAPCSTAICLKMYLCQQFIQAHGGNIGAMSNP
RQGLTFWFTLPSSG
>Ava_4869 Transcriptional modulator of MazE/toxin, MazF
MVVKPPYFPNRGDIVKLEFGSAQQFTAESIQRVFTLRNSGMSFDDIAITL
NNELQQQGREQTGYRPVLVISPIKYNQMASLVLACPITTNPKGLKFEVPL
IEGMKTKGVVLADQIKTLDWKARKVKFVESVTEDLIEEVQAKLETLIL
>Ava_4136 Response Regulator Receiver Signal Transduction Histidine Kinase
MKIFNIFEKATILIVDDNPTNLKVLSDAISSLGWEALIATDGESAIEEAE
YAQPDIILLDVMMPGIDGFQTCTELKKKSSTKHIPVIFLTALTDQFDKVL
GLVTGGVDYITKPFNLDEVLARIQVHLKLSFLTKELQIKNQELDKLVEER
TQQLSLTLHKLQESQLHLVQSGKLSTLGELVAGVTHEINNPLNFVMGNLG
FLRNYINALTKHLQLYHQYYPHPVIDITQNANIIELDKILIDIPKLMSAI
DTGLERINNISDSLRNFSRSDISKKVFFDIREGINSTLIILSHRLKGNKL
RADIEIIKDYGDIPVCECYPEQINQVFMNMIANAIDAIDELCQKTADMQN
NQNHKIIIKTVWKQEEELLIVTFKDSGVGMSAETQKQIFEQFFTTKPSGK
GMGLGLSISRQIIEEQHNGRLRCCSVLGEGTEFLMEIPVR
>Ava_1561 Response Regulator Receiver Signal Transduction Histidine Kinase
MEETLKILVVDDDEVDRMTVRRALVKAGVRMEMSEVSDGNTALSILRNTS
FDCAFIDYRLPDQDGLNLIETIRSLNIKIPLVVLTSQGDEQIAVELMKAG
ATDYLSKFRVSSETLAQVLRNAMRLYRAEMQTAIAYQQLRESHEQLVRKN
QELERQRQQIQIQNLKLLEASRLKSQFLATMSHELRTPMNAIIGFSQILL
RPKFGNLTGQQADMVERILNNGKHLLMLLNEVLDFSKLEEGRLELKPELF
DLTKVINAAVAEMRSLAEAKKLSLLVQIDLQNPLLVNDPVRIKQILINLL
SNAIKFTDSGSIWIDVKDLPGSWVEIRVKDTGIGIASKDFKYIFEAFRQV
DQSITRKYAGTGLGLAIIDSLVQMMSGKIILESQLGVGSIFTITLPRQLP
LSNLSLSSSSVQDAKEMMQPDHKVHHPTAKSNPAPRKYHNLKL
>Ava_4085 Two component Transcriptional regulator, Winged helix family
MKFLLVEDDERIAASLTEALTDNNYAIDVAGDGEEGWDFITAFDYDLILL
DVMLPKLNGIELCQRLRQRGYGLPVLMLTARDSSTDKVLGLDAGADDYVI
KPFDLKELLARIRALLRRGNTTISTFLEWGGLRLDPANCTVTYKEQLLLM
TPKEYQLLELFLRNNGYVLSRRQILDHLWSSIDPPGQDTVKVHIRGIRQK
LKAAGAKDDFIETVYGLGYRLNQNF
>Ava_A0002 Protein serine/threonine phosphatases
MTSPSTDASSSLVIQENQSFQIDNFQVEVLSYLGQFTSDVYSFKVKICSI
DSNSTQSKLGLLRVGSDRGGLHREIQLREALADYKMIAELITHITAESVI
INPLSPILDIENQENKQDEIKNKTEDTENTTNSENLILHENVTDGNETKS
AIDEDASYLSSLLEVDSEYLEDEYYPQIEICSADSGSKLILLSDFPENTT
TLDTWLKSEYSLEEYLYITSQICQFFRYVCERNWCFISLEPRMIQTGTPS
RFFDLTNAYPVGEILTSGLLGNYCASELAYNNNPIHESMSSYTVGALLYH
SIHKQPLSPHQSIDLKISPIPRIYQILKICLSSIPEERFPLSQLLTILVE
TRQAIRAPKIKWNVASRSTVGLSTSRLQNEDNYGVRQQQLSDIETMILGV
VADGMGGMSQGEVASKLSVQTVLDEPIPPEFKTVGQRNEWLMSLFQKAND
VVSKNVKNGGTTLSVVLAIAQQLMVAHVGDSRIYLLRQGEIRQLSEDHSL
VAMLVASGQITEAESLQHPDRNVLTKSLGSKSKLSDGYVQDLKRTTQELS
MTLENADILLLCSDGVWDLVAKNEFVEIFNNNKDLQAAVDTTIEQVIERG
ASDNATLLAMQYQMEKS
>Ava_1549 FHA domain containing protein
MTVETLESHLLILEDDQGRKEFSLDQPLYSIGRDKESNIRLVSQFVSRRH
ATLVRLPKNNNSYYYRIVDGDGKGKASANGLMINGRKIPAHDLKNEDEIV
FGPKVRAIYYLLKNTQRSGQTDASEYDITLINPGMTEDAEEL
>Ava_0989 Ionotropic glutamate receptor
MISAIAQKFSQFLAARNIRRFLKLHIWLGMVCGILLLFLVVHPVQSQEPD
NQKSLVVATRAIPPFVFNDNGELSGFSIDLWRSIASQIGAESKFVEYPNV
ADLLSSVRNGKANAGIAAISITAERQQQFDFSLPMFSGGLQILVRNPKLS
NSGTPNILSLFFSTTILQVLGLALFLIVIAAHVIWLSERHQKEGMISPSY
FPGIFKACWWAAATLATQADEMPKGVIGRILAIIWMFIGVLFVTYFTAAA
TTSLTVQQLQADINSVSDLPGRVVATTTGSTAATYLKQQKISVLEVPKIE
QAYDALETKKAEAVVFDSPVLLFYAANQGQGKVEVVGSVFREENYGIVLP
NNSPYRKPINNALLKLKENGTYQSLYDKWFGVKNS
>Ava_2239 Adenylate/Guanylate Cyclase
MKSPVNSKPKILVVDDEPDNLDLLYRTFYRDYKVLRAISGPAALDLLAQE
GEIAVIISDQRMPIMSGTEFLSLTATQYPDIIRIILTGYTDVEDLVEAIN
AGKVFKYVTKPWEAEELKAVVRQALDTHNVLKARTRELTRTLRQESLLNT
VTNTIRSALDYRQILQAIVDTVGHMLEVDVCLLRSFQDGQLVDEGFVYQK
YSPAAIEKTIHNSAPLTILADTVWETREVQIIHDVAGDERLHGDSPELQH
RTDAFAAADIRSSLVVPLICQQELMAVLALHQCSQARVWGEEEVQLVLMV
ADQAALALSQAYAYEQVRALAKRESLINTITTAIRSSLNPEDIFAAITQK
LGQALQVDGCVLSLWTEEDEFVKCVGLYDSSRHSEDSLDNHRLITQELPE
SQAPILENPILQEILKTHQPVIITDMNHSDWETKRFDLNLKMPARSLMVV
PLLADGKCIGSITLREGKKARQWLSADIELAKAVAAQAAIAVQQSHLYQK
TREQAERLLQLDKQKTEFFQNISHEFRTPITLIQGPLESAVGTGEGLSYA
QSAIALRNSRRLLRLVNQLLDLQRLDAGRMQPSFRPCDLVDFVSQIVESF
RPYCEKKALHLTTELDECPTVYIDMEKFDKVVYNLLSNAMKFTPEGGTIS
VKLQSQGHHCILQVQDTGIGIVKEQIPHLFERFRQAEGSENRSYEGSGLG
LALVKELVELHGGRVTVESVYGKGTTFTLWLVIGNAHLPLQQVSDTPVEL
TTSRASVELADLELVETTLENIDIETINPLPISETQQHTANSTQQSTHSI
LVVDDNPDLRTYVSDILRRSGYQVYTARNGYEGFSKVQELVPNLIVTDLM
MPLVTGLEMIRMIRNDEKVKGTPIILLTAKVDEETRIESTEHGADAYLAK
PFNDRELLAEVRNLLALKENEKRVLELNTYLTESVLKRFLPPALVSKAAA
GSLSLDLRPEPRLITVLFSDIVGFTQLANTLRSRRVAELLNEYLEFMTKA
VFDNGGTVDKFMGDAILALYGAPEELTPNEQVRRAVNTARAMHSSLAQLN
QRWRDQGIFDTHDYGGVQFRCGIHQGTAVVGMFGSAERADYTAIGPSVNI
AARLQSAAVPGTILVSAAVADYLQDEEITKGSPLKLKGIDETVLTFAVKS
ELMVNR
>Ava_0066 Response Regulator Receiver Signal Transduction Histidine Kinase
MNPIQILIVEDEQLVADDLRETLEHLGYGVPALVASGEEAIFMAGNLRPD
LVLMDIRLEGKIDGIEASFAIQSRFDLPVVYLTANADRATLERAKASHPF
GYILKPFDERILATTIEIAISRHQTEVEVKKALIAAKNSQQIAESKNQMK
SQHLYMAAHEFRNPLTTIKLSAEMLNTYGKQMSEEKKQKHIDRIESATDS
LTNLLENILTLGRAEADNFVLNPTLIEVVSFCEEIVESLRLTLKEHYEIS
FVTNTQSFIACLDEQLLWHLLNNLLSNAVKYSPRGSTILLGLTCDESSVY
FQIKDQGVGIPLEFQAKLFEPFQRAANVATIPGTGLGLAIVKQCVDLHQG
KISIDSTLGQGTSFLVRLPLKVNSISA
>Ava_0541 conserved hypothetical protein
MVVISIPVVANAIDLVTKLIRVVANTIDLVTKLIRVVANTIDLVTKLIRV
VANTIDLVTKLIRVVANAIDLVTKLSF
>Ava_0434 Serine/Threonine protein kinase
MSLCINPQCSKPQNPDNVLFCQNCGSELLLEGRYRVVSVLGGGGFGKTFA
VNDTRTQTAKVLKVLINNHPKAVELFQREAEVLALLNYPGIPTVEANGYF
VYFPRNSQEPMHCLVMEKIEGLDLGQYLRQRDYRPIDQKLALQWFKEVMI
ILHQVHQQGLFHRDIKPSNIMLRADGRLVLIDFGTARSVTGTYIAKQAVG
QVTGVISAGYTPSEQINGQAVQQSDFFALGRTFIYLLTGKEPSDPTIYNY
LNDELRWRDGLLSSGSNSVTPTVGDRPNILPQFADLLDQMMERLPAQRPQ
NTHIILQRLADIEKSLQPPPPPPPKPKGWTRRRLIAVVGFSSLGLTGALA
LSRLLPKTTLIVSQEGGGDYKTISAAIENAQPGMRILVRPGLYQESLVLD
KALKIIGDGVKAEIIIESKDAGCLVVKTDQAEVRGLTFRSRVGTENKQYF
AVDISQGQVILADCDITSDSLSGIGVHGATANPVIQKCQIHDGKQSGIYL
YENSRGTIEDCDFFGNTTTEITVDAAQPIIRRCKIHQDKEGGILFRNQAQ
GIVEDCDIFNNNLSGIEIRDSSNPTIQKCRIHDNQQGDGILVHLNGRGTV
EDCNIFSNGFSGVEIRDRGNPVIRRCSINKNKYYGVYAYKNSTGTVENCD
LTGNIRSAINVDETSQLQRSGNVE
>Ava_3467 PAS/PAC Sensor Hybrid Histidine Kinase
MSNVDQVNYELADEVTALRQRIAELEQLEKQYQYKQVELERRIEDLQAKL
RTPNIANVDIERHPEPVTLQRLQQEISQRQQVDAALTESEERWRLALDAA
NLGFWDWNVLTEKVVWSENHELLFGLVPGSFDGAYETFLCCVHPEDRESV
MQVISACLNNKTDYYDEFRIVWPEKSIHWIAAKGRFFYNEQGQPVRMIGV
CMDITESKRSEENTRQLATQVQEQANILNAILATSVDHIYILNRTGHYQY
VSYGGAAVLGLHPQQMIGKTVQEIDLPQELIDKMNGQFLTVMKVGEPIKD
ECEYVAEDGKHYYEYILTPLRNVNHSIEGVITVSRDMTEHKRAEQSIRNS
EARFRRLFESNLIGVAFWNVDGFITDANDAYLQIVGYTREEFDTLGKINW
RELTPPDCEHLDTRAIAEVKANGISRIYEKQYIQRNGRRVSIVLGIALLD
DSDEQGVAFVLDISERKLAEQQRDRLLCAERIARKDAEIANRIKDEFLAV
LSHELRTPLNPILGWSKLLRSRQFDAATTDRALETIERNATLQTQLIEDL
LDVSRILQGKLSLNVCPVSLPIVIGAAIDTVRLAAEAKEIKIQNVFDPEL
GQVMGDANRLQQVVWNLLSNAVKFTSPGGTVEIHLKAVNDQAQIQVIDTG
KGITPEFLPYVFDYFRQADGTTTRKFGGLGLGLAIVRQVVELHGGTVQAT
SPGEGLGATFTVNLPLSPKHEAMNHEDKNPVSANFQPATLSGVRVLIVDD
EPDIRDLVTFILEDYDVEVIAVSSAQEALEALSQSLPDIIVSDIGMPDVD
GYMLMRQLRQRSPQEGGNLPAIALTAYAGEMNQQQALAAGFQLHISKPVD
PDALIEAIGNLVNNQ
>Ava_0364 conserved hypothetical protein
MAYQNITASLSAEDVKEIKAAFATIQAKLPFLVTLSVEERRKLFKMGDKS
LAFVNTSLTAAQSNPDILPASFDVEEFVRDYQLATTLTELLIGLRQLTEQ
VDDTLLAVGSEAMGSSLTVYDYVKTAAKKTPGLKTLAEQLGERFKAIKNK
PAKAATGS
>Ava_1137 Histidine kinase, HAMP region
MKYFRRLFYPPAWPIAAKISVALVCAVLVPMIFTAYYNLQQSLNSVEAGE
YHKLELLASSSASRLDQLIIDYHRVVAQISSDRHVVDFLSATTPENRKAQ
GHNLQQTIHNVLRSHPNLDVVLLMDKNGRCLAATDSQFIGENYSHIQGNF
YGSSTLLGEASQNPGMFFSQPVRSPHGEIIGLTVIKIRQADIWVIINALQ
LLGSQNYVFVIDQQGTIISHPDPSVVNHSPNIPELGVMVKAKQPGHATYH
LPKSHISQIVGFAPLATQPWVLGVSQPNAEFTAPLHRLIWLNSSSVVIVG
GITAIIALLSGLSISRPIHALTAAAQALEDDNFDADVVELHQSLAELGHR
EDDIGQLVRVFSEMAEEVRLRDQRLKMQVQELRIEIDQTKRANYVAEITE
NEHFRHLQQTIQKLKQQEITTHETEKEYYQRLQIQVQSLKERSLNSKNQP
LTEPTEHT
>Ava_3063 conserved hypothetical protein
MESLQQQILAMSHKLDALYQVIEQLDVRVAQAFSECSLARTEAKDNYLEN
NEAGNYQFKGQIGFNQELEHKDVLIDGVYLDMSRQSGEKIISPEIQIQRL
TAQLTAAYNRIAALEEQLLRERIH
>Ava_1016 Possible circadian clock protein KaiC
MSEKEQPEQQNTSGNGVEKIRTMIEGFDDISHGGLPVGRTTLVSGTSGTG
KTLLSLQFLFNGISFFDEPGVFVTFEESPSDIIKNAHIFGWNLQRLINEG
KLFILDASPDPEGQDIVGNFDLSALIERLQYAIRKYKAKRVSIDSITAVF
QQYEAVGVVRREIFRLVARLKQLNVTTIITTERSEEYGPVASFGVEEFVS
DNVVIARNVLEGERRRRTIEILKLRGTTHMKGEYPFTITNDGVNIFPLGA
MRLTQRSSNVRVSSGVKTLDGMCGGGFFKDSIILATGATGTGKTLLVSKF
LQNGCVNNERAILFAYEESRAQLSRNAYSWGIDFEELESQGLLKIICTYP
ESTGLEDHLQIIKSEIAYFKPARIAIDSLSALARGVSNNAFRQFVIGVTG
YAKQEEITGFFTNTTDQFMGSHSITDSHISTITDTILMLQYVEIRGEMSR
AINVFKMRGSWHDKGIREYNITADGPEIQDSFRNYERIVSGSPTRVSIDE
KAELSRIVRRFEDKQGSDS
>Ava_0662 Response regulator receiver (CheY) and GAF modulated Serine phosphatase
MTETKVEKLKLMVVDDEPDNLDLLYRTFRRDFHVYKANHARKALEILAQE
GEMAVIISDQRMPEMNGTEFLSLTVEKFPDTIRILLTGFTDVEDLVEAIN
SGQVFKYITKPWNPERLKNLVEQATDTYRLVKKRTHELRRSLRRESLFNA
VTTAIRESLDYESMLQKIAATIGQTFEATCCLLKPVENNRLTANQFYYRN
PAYNLPDSAFDPTTLIAQVLETGHYQIAQDIYNDNPCNYLVVPLSYQQHL
LAVLALYQWGREHPWQDEDIQLITGVAEQAALAVSQAKLYQRLQEKQQQI
SAELEVARQIQNNLLRQTLPDIKSAKLQACCYPAREVGGDFFEIFVHPTK
GDVWLAVGDVSGKGVPAALFMASAISVLRRELAQEIPAEPNVVIHNLNHA
LCDDLISNNCFITFVLARYTPTTRELVYANAGHIYPLVWSNQTAPEKPNY
LTVRGIPLGILPKWQAKSGSLILAPGDTLLLASDGITEAMVSNSLFETVK
TVGGVQPATHSMLNQDGLWQLLQKEPQPLSLNHLLSRIQADNHVQEDDQT
ILSLEVL
>Ava_3244 Predicted signal transduction protein containing Nacht domain
MANQDHLSEILDRILKGNQTEADIDQLLRSLKTVNGILQSVSQNGKFNNN
IGQITGGDIQIGDRIYQGADAEIIREIIRSLLEELKATGQFVPFKEQNQQ
SVDKLVQQVQSRIHDDIQRLHGTMPLWGVDHWVPLGDLFVDVNILEELSS
SRKSELDDLWQDFTTGIERYSGDRSLDRIGLGKERQRVSGLEVLEKNTNL
MVVGKPGSGKTTYLQRIVTECNAGNLQAHRIPALIKLREFVEDGRKFAYS
LERYFEQCWQLSNKEIHLIFHQGQALVLLDGLDEVTGEDGKNITKQIKQF
ARSYPQVQVIVTCRTQSQESRFERFDYVEVADFNQAQVRLFAEHWFQAVI
GDDSAGITQSQEFLNQLFLEANQAIRDLVITPILLSLTCAVFHQTGKFYS
KRSKLYEEGLEILLEQWDKSREIERDEIYRDLSPERKLELLSYLAVKKFE
QPQYVLFEQSEIEGYIAEFLGVGLRDSRAVLKTIESQHGLLIERSQKVWS
FSHLTFQEYLVAKRFCNQGNWQFLANQITTSHWREVLLTASEITNDPDSL
LKLMKIKIDTLLAGNEKFQDYLIWLSTKASSLKFSYSQAALRALCMALNL
DEEDFELPYNLGIDLDFNFLPNEPSNDERLISEYAVDRNLRLALHFSSGN
RGVESKTFRVPINIILQQIIDNELQYLCPRNFQMENEILQLINKLPDWWI
NENSFDNVMINKIDDWWQINGDSWINNLRKLMIKHRNFGHNWCFIQEQTD
ILEKYYNANTLLVECLNSSNVSRETKEQIEQLLLLTIAEIEKRKCETGK
>Ava_2491 Possible Transcriptional Regulator, Crp/Fnr family
MNIELFIQRAEALHKQLADLYQTASVLPWIPPDLLPQAFKELYSNSKLVQ
MAAEELYHQNEELIQTRSLLEAERQHYHDLFEFAPDGYLVTNAEGIIQEA
NLTAANLFNAPKHILVDRSIINFIRLEERESFRCELNQLFQTDKAKKLIV
RLHQFHGESFDALLTISVVRSQNGKIKSLHWLLSHINENQQQNLGLVNHE
NYLSQNRSVYVYAKGENIPLNPLVIWYVRQGLVKLSTFCETGEEVLMGLV
KTHMVFGSSMTSLPIYQATALSEVELVSINFAEIAVSQMLSHNLLPKINQ
QLQQKESFLVIAGRRKVEDRLYHLLQFLKQEIGEPIGEGTRLSVRFTHED
IASACCTTRVTITRLMGKLQQQGLISFDSKKHMIINKRLEDRA
>Ava_0506 chemotaxis sensory transducer
MKLGGEQMAASIEEYLEKYQQACTAYAEQKYEVAASLVDQVVQNVPDDPN
SHLLRGHIYYVLQQYDVATAEYEQVIQLTDDFELIGFAQSGLENISQYQQ
SKSIAEQSANLHNNESIDLGVFTFKESAELELEDLGSIEDFDSNNFDLNA
LETQQSLVTTEDLSLDNPFETPTDSISFNKNPESIESIPAFSDDPFALNL
EQEEEQKTNSHQEQVELELPMFWQEDSLEEPQTDNLLEIGTEEPTDNPDS
VVGHHQSNIDSPFAEFDTTNSFIGQASVAEFLIENGQEDTTDELDINKSK
PEPENSSPNKEELVNGFIPLENLPDDSLDDIAHPESNNWLQEIASQEEIL
ESPASVNSGFTMKSPSPDILKEEMNNFDVDESFDFEAFESAFGTESITND
EDTSIIFNKENSKSNIEFLDDFDEFDDLGNIPGFDLAEADSSFSDVMLSS
STDINSIPRGKAAETANNATERDEELFSITGSQEAVPIFSQTDVPKVEAN
INVEQGWLAPLENASLDTKPWLVGGVVGVFSALVVATVSFTATNIAPPQQ
RESLRYTSWAMSLAAGMTGFATAAFMGSVTIKQVRRTTKDLQAQFDAVRQ
GSLNVQATVYSNDELGQLSAGFNEMARVIFTTTNEAQRKADEQEEAKENL
QRQVIRLLDDVEGAARGDLTVQAEVTADVLGAVADAFNLTIQNLRDIVQQ
VKVAAKEVTKGATNSETFARALSSDALRQAEELGVTLNSVQVMTDSIQRV
AEAAREAEKVARDASTIALKGGEAVENTVAGILEIRETVAETTRKVKRLA
ESSQEISKIVALISQIASRTNLLALNASIEAARAGEAGRGFAIVADEVRQ
LADKSAKSLKEIEQIVMQIQSETGSVMTAMEEGTQQVIKGTKLAEEAKRS
LENIIQVANRIDILVRSITSDTVEQTETSRAVAQVMQSVELTAQETSQEA
QRVSGALQNLVGVSRDLISSVERFRVETMETR
>Ava_3036 Serine/Threonine protein kinase
MNRFSGNITNLHQYNLQQNQLAQMCGSKELFCDRYQILRILGRGGFGITF
LAGDAVLPGNPLCVIKQLCPKVTSAKSWQNACQRFQKEAKTLAKLGSHSQ
IPMLLNYFEGDGELYLVQEYVRGYTLSQEVRHHGIKTEAEVKRFLLELLP
ILQYLYQNQVIHRDIKPQNIVRCADDGRIVLIDFGAVKEKLSDVGLSSFS
QNAHTNFVGTTGFAPPEQFSLRPVYASDIYALGMTCIYLLTGKAPLEMEN
NSKTGEICWHKYVKVSDDFAKIIRKMVKFSLDERFQKPQDVIEALNKERD
LPNFSDCLTSQPLSNKRQTKVETSEKYVPSVTRTAMAIREWKAKLQQKQL
QRSLQHFSSV
>Ava_4889 Two Component Transcriptional Regulator, AraC family
MTNESSKTILVIEDDSDSRNLFLAVLEARGFDGIAAENGASGIQQAQKYL
PDLIICDIMMPDMDGYDVLNVLRQDPLTAIIPFIFLTGNDDKAGLRKGME
LGADDYITKPSTIEEILKAIAIRLEKQAILRYWYATKSHQLTESLAVDSE
AIFPSTPQLQEVFDYIEAHYHQGITLSNVAVAVGYSPAYLTSRVARETGD
TVNGWIFKRRMAAARPLLRNTNKTIEQIATALGYQNACHFSRQFRQHHGL
PPKAWRKQQQSLQSVRNLKPQLIDVCPQSEKCLLTGRS
>Ava_0353 Serine/Threonine protein kinase with FHA domain modulation
MVTLTLLEPQQKTPLKQWCFENSSVIRIGRAADNHVILSDNLVSRHHLEI
RQVSSGGGGSWQVLSKGTNGTFLNGVLVIQDALPNNALLQLAQGGPILQF
QVQGIIPPEWQSISGSDSPLSGVGSSAEKISPELSNNPGSLTCTHEGNSP
QNLFCIHCGQPLSVIQTIRHYQVLRTLGQGGMGTTYLAWDAAGVIVGHPK
LLVLKQMNADMARIAKAQELFEREAYTLKSLNHSGIPKYYDFFVEGGKKY
LAMELVHGQDLEKRIYATGPVIPSQAIAWMIQTCDILDYLHSQEQPLIHR
DIKPANLMVKTANNQIAVLDFGAVKEIGTTPGTRIGAEGYCAPEQERGQP
LTQSDLYAIGPTIIFLLTGENPFKFYRQKGRGFRFDVSKIPTVTPKLRDV
IERTTEPLPRDRFQSAKELAAALAACK
>Ava_B0234 conserved hypothetical protein
MNKWVILSGIEGNLAAYEAVMADIKRQGNSVEALYILGDLVGPRPETEKL
VERVLNPRQGELEPLICKGWWEEQSLILHGLGPTGDAPELMAKYGGDTVK
LLWDSVSRKTVQWLRSLDFGFFELDCLLIHGSTVGVNDELTPETSPIQML
DRLRRMQANNLFCGRSGLTFQYQLQTGSITTALTTLDNQVSPHTVTVTPR
QVIGVGNVGRTPGQATYTLYNPGTNQVEFKTVYYGNSKGFQSQHKNTKSK
SKV
>Ava_0161 phage shock protein A, PspA
MGLFDRIKRVVSANLNDLVNKAEDPEKMLEQAILEMQEDLVQLRQGVAQA
IAAQKRTEKQYTDAQNEINKWQRNAQLALQKGDENLARQALERKKTYTET
STALKTSLDQQSTQVETLKRNLIQLESKISEAKTKKEMLKARITTAKAQE
QLEGMVRGMNSSSAMAAFERMEEKVLMQEARAQSAAELAGADLETQFARL
ESSSDVDDELAALKASLAPAPEQNLLPPQQQEQQSTAPKSKEVVDSELDA
LRKQLDQL
>Ava_2152 Histidine Kinase
MNCEQEIQRLEKANRILQKKLIRSEVDRVRLEETNSKKETLLKNVINELK
QSQIQLEDRRHELEKTLFNLQTMQDKMSALGSMVADVAHEINNPVGFIMG
NLNPAFEYIHELFRLLDLYQQYYPEPCPEIQAEMTAMDYEYVREDLPKLI
SSMKEGTDRISKLSNSLRTFSRTDAEYKLLFNIHEGIDSTLYILQHRLKA
TQDRPQIQVVKKYADIPLIECFPGQLNQVFMNLLANAIDALEESNFGLSF
AEIEQKNNQITIITSLFANSILIQVQDNGFGISNELKSKIFEHSFTTKPV
GKGTGLGLAIAQQIIVQKHGGRLEVNSVPGEGSEFIITLPIE
>Ava_4764 Serine/Threonine protein kinase with Chase2 sensor
MIIGISNKLRAAFIKDKSYRDTAVNKNWWQIILVTSLGVTALVWGVRELK
WLQSWELKAYDQMLRSRPAEPPDSRILLVTVTEEDLAKKGWNLADDTINR
LLTKLASYQPRVIALNLYRPEQTNLGAGLENPTNIISACLSSSMGRSEVP
PPPNFPPENIGYNDVISDIEEDQVVRRALVFSEANDSKCATQFSIAALAA
ITYLEQTGIHVDFEKHQFHLGKTAFPILTPNSGSYKGVDAKGYQILLNYR
HPNHLAPTFTLTEVLNNQVNPNLVKDRLVIIGTTASSIHPGLYTPYSAAK
GQPTRTPSVFIHTQIASQLLSTVLDGRPLIWYWPDWAELVWLWAWSLVGS
ILAWRLKHPLLVVVVLGIALTGLVIICAGLFLDAGWIPLIPPALTLVMSG
VSVIIYRTYRTQQQTKVIMLQVEKQQEVIEQLNILLNEATAIADTTAFYD
QHSHHDSVVVTPRKKADDLLLGGRYSISSVLGAGGFGRTYLAQDTQRPGN
PTCVVKKLMPARKDTKFLQVARRLFITEAEILESLGQHQQIPALLAYFEV
NEEFYLVEQYIAGHTLYEELPPVTGLQSEAFVIEMLKGVLEVLAFVHEHR
VIHRDVKPTNIIRSAEDNRLVLIDFGAVKLMQPPTDQKTELATVAIGTRG
YAPPEQFAGHPRLASDIYAVGMMGIQALTGILPQELPPDPETGNVMWRSH
ATVSEELALILDKMVRYHFSDRYQSAATVLQDLNRLSSLIQTSSIS
>Ava_3443 Putative Anti-Sigma regulatory factor (Ser/Thr protein kinase)
MLGIMQHDHLTIKSELKLLNQVQQWFEDFSLKYLSQLGWTEGQLYRLNLA
LAEGFTNAVRHAHRTLPPETTIEIEVSLWINKIEIRIWDHGNPFDPDAIA
EPAPGTLQVGGYGWFLLRRLADRVVYERSEDGRNCLVIVKYAKEGQY
>Ava_3692 Cyclic nucleotide-binding domain (cNMP-BD) protein
MLSSVDRLLFVRRVPIFKELRDDFIVRLTSVMHELQFPANHTIFRQGEEG
RSLYIIVSGRVKVHIGDKQLAEVDQGKYFGEMAVFDTQPRSASVTTIEPC
EFLELTQEQLYDAIEETPEIAVNIIRELSRLIRGLNENVNMSKFSS
>Ava_1692 Cyclic nucleotide-binding domain (cNMP-BD) protein
MSTPAYLQLNTVLQNFAEIPADEIQKLNQTFYPLPLTAGEFFIQAGDIPW
QIGFVISGILRLYYVNSSGTEFIKSFCPEKHFVAAYSALILKQPAQFSIE
ALEDSLLLVADYDKFTQLCAGHSCWQTIKHKFLEALYLKKEKREAELLLD
DATTRYQKFLAEYPHLDHRVKQYHIASYLGISPVSLSRIRKNFHPD
>Ava_4896 Response regulator receiver domain protein (CheY)
MDRQPLILVVEENLHNLELLNSHLKTLNYDCICAKQGVRAIILAQTQRPD
LIILDMILSDLSGSQVINHLKQDSKTANIPIIAVVPFILVQNQDRLFLTG
ADDYITKPYNFIQLNTLINHYVNRQHSSSLLLE
>Ava_C0116 Two Component Transcriptional Regulator, LuxR family
MSQATTIRVLIADDHAIFRQGLATIINRDPEMQVIAQAENGEQAIAAFRE
HQPDVTLMDLRMPEVEGVAAIGAICATAKSARIIVLTTYDSDEDIYRGLQ
AGAKGYLLKETEPDELLNAIRTVHRGQKYIPPDVGAKLVQRLSNPELSER
ELAVLRSLAQGMSNAEIAAALSIGEGTVKSHVNRILNKLDVSDRTQAVIV
AVKRGIVSL
>Ava_0802 Histidine kinase, HAMP region
MPSNGQSSFRRILVTRILLLFVPVLFVGQIAALNKARSSLLKTARQNLTE
SAVIRGERILNAIATLKTNLLTASRTTVVQSGSPEEIEAFLTQLVQALPN
YIECLQLINWQNGEIVASSCGKKEITQFGPLLPSDSVELRSIAPPKPGVT
GPRNPQEQLQLLLTAPVYDKSGKLRYALNLQSALYKQTRNQPGSLTGSTI
VIAEDGTILAHPLSDLVGTNIKEHSDAKQVQNIIKNAIAGRNEPINLIFN
NKKELVAGYTVIDSPTTIQPQQKWIVMSVTTVENALFGLEEIKLILIVLT
VGLIGASLVASLYLAPYLASPVEELRDYALNIHSHHTSRRVPDNFKIREF
NQLAQAIDQMVDRLKVWSEEIETAWKDAKSANQVKSQFLATTSHELRNPL
EIIYKVNL
>Ava_3669 Putative diguanylate cyclase (GGDEF domain) with PAS/PAC sensor and Response Regulator Receiver modulation
MVSRKILVVEDEAALALNIKNSLQALGYNVLEITNSPQEAIKKVAEKHPD
LVLFDIRLSGEINGIQVANIIQDNFHIPVLCIIEYSQHLELHNKQLDESF
AYLLKPFAEKDLHLAVEMALKQYQIYERLQEETAKKAAIINSMGCGVIVT
FTNGQIQMMNPMAERLTGWMQHEAFGKDLAEVVNLVDKDMDEVIDNLATQ
AMQTGEIVNLPENCTLISKDGKEIPIGDKIAPIRDNTGNITGAVLVFQDI
TQRKQSEVQLLRNAFYDGLTTLPNRILFLDRLKQAIERSKRRNDYRFAVL
FLDLDGFQGINDRFGHGMGDDFLVAIAHRLESCVRSGDTVGRFGGDEFAV
LLEDIRDVNDAINVAKRIQDTLGLPLNLNGHQIFTTASIGITLNAGSYDE
PENLLRDADHAMFRAKQQGKARYGVFNKASNC
>Ava_3089 Response regulator receiver domain protein (CheY)
MANNSEELHPQNVTNYFQSLDGLHILAVDDNADSLFLTTCVLESYGVQVT
TATSALEALETTKQLKFDILIFDIAMPNMDGYTLVQEIRNNALLENRNIP
AIALTALGSEDALNMAFMSGFQGYVNKPLDPNILVAEILKLIGSSVLENG
TNSH
>Ava_3005 Response regulator receiver domain protein (CheY)
MASNKILVIDDTTVVRVKVREMLPPGNFEVLEAKDGLEGINLIRQEKLSL
IMLDFLLPKLSGWEVFQQVQAHPELRKIPLVIMSGRKEEVTEKITEPFEY
FEFLGKPFDQKQLINAIKSAMTKAKLPRQEPVGAVAAKNGNTATATMTHG
AVATVAPPTVATTTTVATAGIDADAAAEIQALNDKVAKMQAEIEGLKKQL
AQVVTFIKQKIK
>Ava_1523 Forkhead-associated
MQIQLSWIVPNTGEQREPTLETPVAIGRQFTAMPSENNGQRVSRITIEDD
LTADYHALIDWQNQELIIIDQNTDNGIQINGIQLTNSSLNNGDRIKIGTC
EITIKFTPVTNPGECDRMIGFLFKRRCGRTDTTGCPHCHPTYEEDYAYYS
GYGNYHSGSWGSSYYYNRDRYEYDSETGNIDFTEADAISLENEYDTDYET
NMGAS
>Ava_4807 Multi-sensor Hybrid Histidine Kinase
MLEFNHLRLHNMHGSLVAKIASAIATLVSSSILIGWLLDVELLKIFFWGS
SGIMTPNTALCFALCGISVWLLVTKPSGTSHSSQSHKPYQKLSRAFSVSN
TIIAALAICEYLCGWESGIDKLFLGDVFTTINTPHMGLNTAINFLLIGIA
LELLTYPRNNRSYWYAQILTLFTTVISLEVFVCYAYKVNFFYTINPNFTS
MSLQTALLFIVLCIGILSGQSEKGLMKIVFSDSYGGLIARRLLLAAITVP
LFLGWLILKGQRAGRYGPDFAVSVFAVILIVIFVIIIWQNAVVIELLSQQ
RDRAQESLKAYEEKLKSLVNANIIGIAFADIYGGIQQANEAFLMMVGYSQ
EDLLTGRLNWKNLTPPEYFYLDEQGIAEAQANPKGACTTYEKEYIRQDGS
RIPVLIGYVLLGEEREESVAFILDLSERQQAQQKILQLNKDLQRRVVELQ
TLLDMIPIGIGIAEDAECQNIKINPAFAKQLQLSTDVNASLSAPPNQRPT
TFKIFHEGRELLPAELPMQYSAVHGVEVLDYEVDVVHENGEIIKLLEYVA
PLFDEDGKTRGCIGAFVDITQRKQAEELLRNEQKWLEDVLNLMPRPLLFI
EPETARVTFANRAADELAGGKFPRGVPAEEYHTVYHFTDINGNPIPNEQM
PGVRVARGERLEGLELDWHTNDEVLSLLIFADTLPAMHGYPATCVVVFQD
VTQIKQAEKALSLGYQRLKLLFSTANDLLSSQEPVALIDSCFQKLAQQIG
LDVYLNYLVEDNSQSIRLASYHGICPELAQKIKFLKFGEAICGTTAQERH
SIALENVQQSTDPKTQLIRSMGIHAYYSYPLIAQGRLLGTLSFGSRSRTS
FTENQKGMMQAVCDQIAIAMERMELINSLQRQTEQLTEANRMKDEFLAIL
SHELRSPLNAILGWAQLLQARRLSEAQTAKGLETIERNAKAQTQLIEDLL
DISRMIRGKLRLNVRTCNLIPIIETTIENINLAAQAKEIDLTFFLENPAT
ENLPFQVSGDPERLQQVIWNLLTNAIKFTPSGGKVEVRLTKNPGCEQNEL
ITNSYAQIQVIDTGIGINSSFLPYVFDRFRQADSSITRSHGGLGLGLAIV
RHLVELHGGTVHVHSPGEEQGSTFTVKLPLLSENKATTIEPISPRGEHFT
PLPLCPSLLGVRVLVVDDESDSRDFVSTVLEQCQAQVRSVPTAKEALQII
SQWKPDVLVSDIGMPEEDGYSLIRKLRSLPPEQGGNIPATALTAYARAED
RTRAIQEGFQLHLPKPIEPTELATVVASLIKRGQRRD
>Ava_2751 Response regulator receiver domain protein (CheY)
MYLTNSFISDNKKHYSQQPLVLAVEDHDDSLLLISYALESIGCRFICQKD
SSATVLVAKEYQPDLIMLDILLPGLNGLEVVRHLKEEPLTQEIPVIAVTA
LATKEDQNKIMKAGFDEYICKPYMIEDLEAVIHRILCGKFYPHSAYQLCQ
D
>Ava_4347 Two component Transcriptional regulator, Winged helix family
MLTSSSMRILLVDDEVELTVPLSRVLTREGYTVEAAYEGKSGSEMATVGN
YDLLILDWMLPGKTGLEICQELRRQGKITPVLFLTAKDTLDDRVQGLDAG
ADDYLVKPFELRELLARVRALLRRSSSQTYEATPGRLTVADLELDCENQV
AYRQGRVIELSQKESQLLQYFMEHTGQLLTHAQILQHLWEDNEPPNSNVI
AALIRLLRRKIEVGKELSLIHTVYGKGYRFGTSSVE
>Ava_2421 Multi-component Transcriptional regulator, Winged helix family
MRILLVEDDELIGELLVKSLTSQHYTVDFAKDGEEGWNFAELYTYDLILL
DLILPKLDGISFCRQLRASGNQTPVLLLTSQDTSITKVAGLDAGADDYVA
KPFDFQELLARIRALLRRGGSALPPLLEWNNLRLDPSTCEVACDGKLLHL
TPKEYGLLELFLRNSHRIFSCSALIDQLWSFEEPPTEDTVRSHIKGLRQK
LKAAGVVEDPIDTVYGIGYRLKPVQSGREEELNLEKVADAIANPVENEVR
QVWKDVVEKIEARVAVIEQASHKLLQNKVSEEILSKAKVEAHKLAGSLGM
FGSDEGSQIAQEIESLLDNGKKLKASGRKHLGQVVEALHQELENLKSGYK
TEPSVVDAKADDRPLVLVIDKDQELVRESRSQSSEAIAPGQLTQARVMIV
DDDPQILTALQTLLSAWGIKVYTLAHSQGFLEAMALAEPELLILKMEMPS
TSGIELCQIARQEPQWAGLPILFLTNRHDTLTRQQIFIAGADDYISKPIV
EPELIGRILNRLEHNRWLQNLAEIDTLTLVANRRKSTQELNHYLQWCHTH
QQTMSFAVVELDGLKQINYNYGHEVGDRILSQLGELLRQMFHSQDVVGRW
GGTEFILGMAGITKGEGVRRLGELLKTFRQIEFITTSNQSFHATFSAAVV
EYPQDGDTLEALYQAADIVLNQAKTSGRDRVLSS
>Ava_3033 GAF Sensor Signal Transduction Histidine Kinase
MTITANSQLPNRFPQNLESMNHKADGLLATLGAELVYVQDGVGRYLSFYW
QKSELLGFNQEQIVCDGNGQEIFVPLDKVSYMKRLHYVMANLAPEKFSCW
FSCHQNLFELELAITPIIPPLGTAATTVLVMGRLLQVKVNNQEVNVAITT
PTQTDLASRSQQHQRLVNKITRNIRRTLDLDVIWQQTVDSLGKALRLERC
IICPYQPSSSKVRVIAEYHQPDRPSMLGLEIDVTSEPAFAQALTTLEPII
MEVPGYKLCPQQKILVVATCYQDQANGLIAINLRHECYPLTNAELELAKE
VADQLGTAIAHATLYKELEAARQKAEEASRLKSEFLANVSHEIRTPLNGM
IGFLKLILEGMADDVEEKNQFLSEAHQLSLHLLNIINDILDIAKIEAGKM
ELVCAPIKLEELFSDVDNFMRPQAEVKNLSFRMQLPPTSDEIVVQGNYQR
LLQVMLNIVGNAIKFTHEGGITVSADVVLKKGKLQEQHFPGMVRVRIADT
GIGVSLDQQDKLFQLFSQVDGSRTRQYGGTGLGLAISQKLVETMGGEVHF
YSLGEGLGSTVTFTVPLYQQPVMLSSNDADAECIG
>Ava_1700 Serine/Threonine protein kinase
MTIQLLNDRYQVIRTLGAGGFGETYLAEDTYMPSKRRCVVKQLRPIQNNP
QIYQLVQERFQREAAILEELGGATEQIPALYAYFSADGQFYLVQEWVEGD
TLTARLQQQGLFTESAIQELLVNLLPVLEYVHSKHIVHRDIKPDNIILRH
RDGKPVLIDFGAVRESMGTVVNSQGNPTSSIVIGTPGYMPSEQAAGRPVY
SSDLYSLGLTAIYLLTGRQPQTLDIDSQTGEIMWRQYASQINPVLASVLD
KAIAYHPRDRYATARAMLDNLQSISSPIPPTQPYFAPPPVVSAPPQPTVS
VAPPANVTGNNQKGILFGSLIAGGLIGASVIVGLAFTRTPQPVAENNNTS
PVNSITETPVSNATPEVTQSPVTTQTIVPSPQQQVDPSPVPSITSAPIDV
NINNNNYLWLSQQAVTDADLDGKDGYTLDIMRNTVFARHGRRFDNPGLQD
YFNNQPWYNPIYSPKEFPLKLLTRLEQRNVDYIAAYQKRYNLRHFK
>Ava_1592 Serine/Threonine protein kinase
MNHHMIGKILQARYQIVQNLGSGVFGQTYIAVDINYPHQPKCVVKQLKVN
SFHSSQLDTIRLRFLTETETLKHLGQHPQIPNFIACFEENERFYLVQEYV
AGHALTAELPIAQNWGSLWREDEVITFLEDALSILQFVHSQGVIHCDVKP
ENLIRRAVNGKLVLIDFGSIQSVNFGIDEQLSIYQVPATSLGYIPPEQFI
GKTQINSDIYALGMIAIQALTGLEPLQLKIDPDSNEIIWRFADTPVSDYL
AAILSQMIRYNFQERFQSAAEVLRVLQQMKWETSLPQLLQTQQIEYRQEP
NSDQPSPLITGMKVGLAVNTLLMGLGTYSLLSTSPANTETEILYKATKEY
QDGDLKRAIALAKLIPSHSNVYPDAQATIDEWQQQWQTAAKQYSLAEQAL
LESRWSDVFVAASEVPNISYWQSKVKDVVEKANVNIEAQTQNLLAKAYDK
ARAKDFSSALEYLRQIPQESSAGALVQQKLAEYNQKKQIRAAYFLHQARK
QALAGNFNHAVNYLRKIPQGTPVYAQAQAKLNEYTQKLRPQIQKAKSLIA
HNSVIQVGNVQSEIQLPEVNIR
>Ava_3623 conserved hypothetical protein
MQENWQILLKQEITNQYVHNSQEWVDLNISTSGLLNLTVVSEEFINLSIP
QRKEQIYNLFKSQVPHLSAGFISLYTPQEADSLNLSAPQVFNTTSVKTWQ
DLAIQAANPQNQPQLLQREPSLPRTVTFYSFKGGVGRTTALTHVAWILAK
RGRKVVAVDLDLEAPGLSTAFNLKPQPKYGIVDYFYERSYLPEGIKPNIS
IAEIFGEVRIPNATGRLFVVPAGFLNLDYVSKVDDLHATTVIDGDQSLWS
VFKVEIYEQLKPDIILIDSRTGINQWGALSLIQAADEAIIFLFPNEQNKQ
GIELLLQSLQSLKKLSINFVFSPVPDITKIGLSKVKEICKSLFERIKIVT
NENNNEEDIDNYQSKIEEPLVVPYIQLIALADNYPVPALLDYYNKIANLI
DEETDDLERKNVLANSEKRWTIIESLQFPEVNAADTEHLGLIFQRTTDFE
KFLDDTTCLIRGRKGTGKTALYSLFLKHKSVGQKLAHGRLDNTVFLSAHG
RFKESRPSRDEFQVIHRHLQQNHGTWESFWRAYLLLRCHQEKLFKFPRNN
KFSRLKEIINKLPTEGWQYESTQALLQMSTHSDLRLIVKDLINIIHQEAK
NKSQKLWFLYDDLDEDFRQAGEVRQQAITGLFQLIQSCDANRLTAIRFKV
FLREDIWNRLIFDNRSHFNGRDILLQWTRVDFLRLALRQVIQSQDFKNLV
DKFSPIAVESIDQASEEVIDKALELLWGSRRRTGDKAKYVSRWVYERLTD
SSDTTFPRSLSILLEGAKEQELSYKGKSSIQPPTDRLLRSKSLELGLKKA
SEKRCDEIREEYPDLAKFFESLKHKSAFLTQDELRTIWQESAHDIADFEE
FTSFLREIGIIEWREKEKRYKVADIYVYGFEMIRQGAV
>Ava_1719 Histidine Kinase
MLISASSDFVALCREQIALLTQGLGASLSVVYLTQELIESPTGEAKLIPV
VAYPETAVILPGEEIAEVNARKQLQVGDMLLLPQQQGKLLAVAPAEETPE
SGRAPTVGGTSSPFGDDYLLDKRQIVLPLVHEGVMMGLLVTSRDDRPWNE
QEQSQVQKVGQTLAIACILDQRRAWLQHQLHQQQILQEQQQDLLDNLLHQ
FRNPLTALRTFGKLLLKRLRPGDPNRDVGENIVRESDRLKELLQKFEQVI
DWTEADLSRLVLPEKEGFVEATVQKEAKPALLLPGTGEQLTDCAVIDLLT
PLLMSAKAIAQDRHIKLKADISQDLPLVRVNIKALQEVLTNIIDNALKYT
PQGGKIYIQAGQEKLNFQGIAISDNGPGIPQEDLAHLGERHYRGVQAQTE
IPGTGLGLAIAKQLIEQMQGEIEIFSPAINSKLTSPNTPGTTFIIWLPMS
QSNS
>Ava_1777 Metal dependent phosphohydrolase, HD region with Response Regulator Receiver modulation
MIKRSGDNTTSTEHNVSGSDPPNKLNSISSNRVSGLQNAKDSSFALSKED
FLVSENTQTTTWLTCGINSGYNSLISGNLQAQISQVKGFDAESPKILVVD
DHSASRMTAAALLGMEGYAVIEADSGATAIKLVGQQQPDLILLDVMMPEM
DGFEVCQLLKQDEHTRLIPVIFITALNDRRSRIRGIEVGADDFLSKPFDR
VELVARVKSLVQQKRLNEDLDHAAQVLFSIARAIESRDPNTGDHCERLVN
LGQAFGEYLNLSRHQIRDLMWGGYLHDIGKVGIPDAVLLKTGKLTPEDWV
IMKQHVLIGEKICQPLRSMQGVVPIIRHHHERWDGSGYPDGLKGDEIPYL
AQVFQIIDIYDALTSERPYKRAYTPEEALCMMLDETEMGWRNPKLMQQFA
EFILSHHKDLGSAE
>Ava_0873 Histidine Kinase
MEFSQVLADNTNIIIAQWVVAVREDRQIESADDLSYTAIKNHIPDVFKAM
VTVLSQSQESDIKSIVTASWQHGLLRAEQGFDPSEIAREYRLLRKVIFDT
IEADLLQGTPAEIIRYMRLIDAVIDEAIARCFHSYVGERLRELEHLQASL
ALHNEELTRLVTSNEDKLSQLAHELKHPLTAIIGYSDLFLRQQRREIEKR
DNTTNIEHIERVLRNGRLLLRLINNVLELSRYEAGKIQLQSAPINIRDLI
NNVCEMLEPLAAEKNLAILVNWVQAPSEIITDGFQLQQIITNLVSNAIRY
TESGNISIVCETVDDQKWAIAVSDTGIGIAEKDQTKIFEPYFRVSSKDRP
YLPDSTGLGLAIVARLVKLLQGEIYLVSKEGIGSTFTVTLPLKLKT
>Ava_2401 Response regulator receiver domain protein (CheY)
MQQTTSEKALRKFLVIDDHESVLSGTVEVLKRHYPEGDFVLAINAESAFN
QLTICPPDLIVMDLSIPEKLGIKARPDTGVRLLRTLMKNYPNLNIIVQSA
HIRTLVRIRPDIDTHKGGFTVADKSLSTQEMLTRVDWALQGLTHTKDIKG
IHTGLEIKPEWLRVLTLAFEEGLQDKAIAEQMCISERMVRHYWSKLQDAL
GVYPDEGKNIRIQTEKRAREEGLID
>Ava_3308 Serine/Threonine protein kinase
MTSILLNNRYQVIQVLGAGGFGETLLAEDTHMPSRRRCVIKQLKPVSNDP
QAYQSIQQRFEREAATLEFLGEHNNQIPRLYAYFSENGQFYLVQEWIHGQ
TLRQLLVSQGVQSEGIVKTILLSLLSVLDYVHSKGIIHRDIKPDNIILRD
VDQKPVLIDFGAVKETIRSVVSSPGYATRSLVIGTPGYMPSEQAVGRPVY
ATDIYSLGLTAIYLLTGKSPEELPTHPQTGEILWQNFAPHVSQKLVSVLN
QAIKPHAGDRYSTASKMLYALSSGWTAQPSIPPSTIPTQQTQALSISAIK
PQGEPIRWTEPNRQKSLFIFGGLIVGGLMAGVAMSTLTRQPQPQTPVVSN
PLPSPVSQIPTTAPNTQPVSPDSSPSSILPDSTEQPVNLDTPSQTETRQE
NPDPPAIFTPAPENTPITADTPTPQPSTTPEPQNQPVSAPPTPADSLPQR
KANTTRPSVPAFPTGTARSSVEAKLGKPNRDLRGVWGNTRAVVYRLVPNQ
VDLGYLFDRNSGVLRQTEVSFAQSVDPEVMQATLNGMLGGQSTAKIQQGL
QKIQQRQSDNFSFTAGGVKGQIVRQNCDLIYISVWESDLHDFVNPASAKG
C
>Ava_3116 conserved hypothetical protein
MAESSEIGPHLTQQWLTEIQTLKQQLIEQQQERDAAWESAEKWRKLYNTE
AEQRRTDTDFFRQTITSLKAEIQQLKGIDGQTLPDATTSVGVQQELAQIR
TVEDLKAKLVEVIKERDRLRQALKTEQENHAQTRKSLTTALGDAIDSLAK
ERGRGGE
>Ava_B0133 conserved hypothetical protein
MGWKAIARSAMGTSHQIQKISCQDYGCYHIFNDVIVGVVSDGAGSAKYSD
IGSKLAVKTVIKCFSEINKFPNKQEELEKKFSQPLSTPEVEQFFIKVVAQ
VLQELENHANNENYSINDLACTLLVFIATPYWLAAMQIGDGFIVVRLQDS
DYQLLFEPDKGEFANETTFLTSKDVIKEMQIKVISGEQSFISASTDGLEK
VAIRLRDWQPFTPFFKPLEEYLQETANPESEDHYLVNFLNSERLNTRTDD
DKTLLLCLFNRK
>Ava_0650 Predicted signal transduction protein containing Nacht domain
MFAIALGFLYKLVYNLYNLYNNGQIVVMAKRSLQASAEGIRKAKQAFKRK
GWTQEYLAAEVGLETRQSIWKFFTGKPIDRHVFNDICFALELDTAEISQQ
SVENSLYLEGDEYSLIDINILVQKLRSIHHEKIQAQCSTLHLLDIARPIS
LNDIYIDVNISEEISSKRWLDIQDLQKVGSYTIISPIFAQRDQKLIGGLE
ALKKYSKLILLGKLGSGKTTFLQSVALSCSQGIFQPNYLPIFVNLKNFAE
DAKDSRQLSLFKYILDQVINFGITEGELKTVLSHGRALILLDGLNEFISH
NYEKNINRINGFIQKFYKNQIVITCRTGTNYSNFHGFTEVEITDFDKTKI
TEFANKWFLIVANNSPEKSRFLAQKFVQRLELEENHRLLELANRPALLIL
CCLAFQSATDFPFHHFEIYKQALDLLLVRYDDVRGIQNNQTVTNLSLLHK
IKLLSHIAAISFHQGDYFLTETKLQQVITEYLLHQSNTITDTDALELEST
AIIKTIELQHGLLVERAKGIYSFSHLIFQEYFIAREIVANANHQTLQELV
SHLSEQRWHQVFLLVVWMLQPVDDLLKLIKEKIDNIAVGNGNLYHFMQWV
EHKSAQVGYVYHPASVRAFYFSIALPPEHPLACNQDLAISLEHQFTGSLS
IDLALDLALTNALTVSMTMTADIFFARLSTLNLALDLKHLLVNQVSLNNS
LQNIRNQLPSSSQGREYLKAWWLANGQAWTEELRDMMINERKIGLNWQFG
KQDLQDLQQYWDASKLLINCLKFARDISPTLRYELETSLFLAKQCQLNVI
T
>Ava_0821 FHA domain containing protein
MTNPQIQLSWEDPITGERREPKLDVPIAFGREFARLPAELDGKRVSRMLL
NSDQISRYHALIIWENNQLIVIDQGSVNGTFINGQQQKRSVLTSGDTLQI
GPYIMMVTLTVRVTAPITNPPSLIQFNPNTNLPDPNLPATPPITPLGNNF
PPPVFQAEQVPVQALHATGLPVDECDYLAVGGGLGSFIWTDLLRISGVRA
EKIVALGLEAEPYARYKRLCLNSQIPLHERLRSNSDSCPDNIWGWPSYAW
RETWQDLTKGNLNTAFRYLWQVFAEPTFAETYTPRASNVFDSIDREAKRI
NWNQIYRYGRVRSIRKTDDGRYCIAYSRGQGNHAFLVSRYLHLATGYPAI
QFLPDLQAYREKYRDFKSVVNAYEAHDHVYEQLEHQGGTVLIRGRGIVAS
RIVQRIYEARRKNPNITVLHLMRSPKPQGNTFQKATRLVKNHYEFQPFNW
PKACWSGELRVMLEQATPEERKRLLTDWGGTTTADRQDWQRITEQGLREG
WYQITFGEVLGVERDAQNRTITKIQEKGFGEMKLTADFIVDATGLDAKVQ
ANPLLEDLVKQYNLPLNYLGRLTVTNDFEIAEMRHGKGQMYAAGAITLGG
PYAAVDSFLGLQYAALVALDGLAAVRAPGVRRLNAVSSFSQWLKWVFNQS
PS
>Ava_2710 Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)
MTSISEDITDGNQAEAALRESEAKFRSLIQNSSDIIGIFEPDGTIRYESP
SVERILGYKPEELVGKNAFDFIHPDDIAGSSESFNYLIQNLGATVLVESR
FRRKDGSWCFLESTGSNLLAEPSVKGIVINSRDITDRKLAEERLVHDALH
DVLTGLPNRVLFIDRLRRAVEYAKRYSDHLFAVLFLDLDRFKFINDSLGH
TIGDQLLVIIAQRLIECLRPTDIAARFGGDEFIILLEGIQDISDTVRVVE
RIQEKLLVPVDLSGHEIFTTASIGISLSATGYEQPEDLLRNADIAMYRAK
ARGKACYEIFNSDMHVQIVERLQLENDLRKAIERHEFLVYYQPIVSLASG
RIIGFEALVRWLHPEQGIVFPEEFMPIAQETGLIIPIDAWVLREACRQTR
QWQEQIPSQSVNLHQQPLSISINLCSSRFSQKKLLEDINQVLQDTGLDAQ
SLKLEITESVIMENGENATTMLYQLRNLGIELAIDDFGTGYSSLGRLHNF
PINGLKIDQSFVSGRGVEAGNLHIVETIVTLSSKLGVDVTAEGVETPAQL
QRLRELKCEYGQGYFFSEPLDSDSAKALIMSNPQW
>Ava_4924 FHA domain containing protein
MLKDQDRGIGFQLKNQDIERRLSLYQIFISLYEQHSHLLNDILQLDNLSQ
SSWANAKPYYIQGVIDESAIYVITNLCNNQTQTLQQPQLTWTIGRDRNNG
ISTYDKLLSRHHAAVQYIDNQGFYLIDFNSTNGSFVNGEQIYQPVRLKDG
DIIRLGSLTFNFFLNYSRRLLPTVTTDFLKPTIPQTQNHRSENSEDTVQI
FIGTDSLESLKYEHQDLKPEHKSEILDCFFQRQI
>Ava_2528 Serine/Threonine protein kinase
MSYCLNPRCPKPENPHDVKFCLSCGSKLHLKERYRAIKPIGQGGFGRTFL
AVDEDKPSKPRCVIKQFYPQAQGTNTVQKAVELFTQEAIQLDELGKHPQI
PELLAYFTQDDRQYLVQEFIDGLNLAQELAHKGVFSETRTIQLLNDLLPV
LQFCHNRQVIHRDIKPENIILRNSDNKLVVVDFGASKSATNTALNQTGTS
IGSPEYVAPEQMRGRAIFASDIYSLGVTCINLLTGRSPFDSYDTNNDTWV
WQQYVKPQVSNYLSQIINKMTASVPARRYQTVEEVLKDLNQHSPVATTPA
KPSHQVPQNPPPQPVSKTQSQIDLELEELKTQFLPGGKSKPQNIQPQPAT
NNNSAKSAIDLELEELKAKYLGNNNG
>Ava_3226 Multi-sensor Signal Transduction Histidine Kinase
MLALLKTIREAIANWWSEFTLQTKLLAAATLVVSLVMSGLTFWAVNTIQQ
DAQVNDTRFGRDLGLLLAANVAPLVADHNLTEVAQFSQRFYSSTSSVRYM
LYADETGKIFFGIPFWEPEVENSLSIERRIQLPEEYPGEGEKPMVRQHMS
PDGTVTDVFIPLIADKKYLGVLAIGINPNQTAVISTNFTRDVTIAVFITI
WVMVILAGVVNALTITKPIKELLVGVKQIAAGNFKQRIDLPLGGELGELI
LNFNEMAERLERYEEQNIEELTAEKAKLETLVSTIADGAVLIDNNMQVIL
VNPTARHIFGWEGADDVVGSNVLHHLPPTVQMEITRPLYEMAAGECDSAE
FRLTLNQPSNRTIRILLTTVLNLQRESIKGIAITVQDITREVELNEAKSQ
FISNVSHELRTPLFNIKSFIETLHDYGEDLSIEERQEFLQTVNHETDRLT
RLVNDVLDLSKLESGRSYSFDGVDLAQAIEQTLRTYQLNAKDKGIELIQD
VAPGLPLVLGNYDLLLQVLANLVGNALKFTPSGGKIAIRTYVLHTKPNSP
NQPTQVRIEVSDTGIGIAPEDQQAIFDRFFRVENRVHTLEGTGLGLSIVR
NIVERHRSKVNLVSEVGVGTTFWFDLILFEDEAPKKMAESGEEKAALPAN
>Ava_0788 TspO and MBR related proteins
MISSWLVIGAVTFLVAVGSFFITPRDVKWFAQLSRPRWLVFEQFIPLIWT
VIFICGAASAYVVWEHDPGGIITWLLMGLYLLVEIITVTYIPLMLRFRSL
KTGEIIGLSGFIAGIVLAIAVLPISGLASVLLIPYLVWSPIGTYTTDELR
QLNPEDA
>Ava_3366 Possible Transcriptional Regulator, Crp/Fnr family
MSSTIFPQTSAVILNDSTINEHLTQRLFTRKEVIPPGKDILWRIESGAVR
TLTWSEDGSFITLGYWGVGDVIGYPLSKVNPYQIECLTSVEAIIIPQHLW
HQYTNNLLTHIQRSEELLSIVHRKPLSLRLWQFLIWLSQKFGRNLENGQL
IEIYITHQEIAEVLNTTRVTVTRLLQQFENEGVLVRYKRRIILCSPNKTI
MNMNLKNR
>Ava_B0208 Periplasmic Sensor Signal Transduction Histidine Kinase
MELTASMTKNISSMLLLPTKLLTKNSRLSRLLVMLGLFVTVVLMEFTTPT
EYVFGYFYTGPILLTNSWFGGAATFGATTIAVFLTILNIFLPGGEVIETS
TVASRAIAAMALIVTGVLSERLRRSQEAITVTRAKLESQQELIKLREDFA
STLTHDLKTPLLGAIETIKAFQQEQFGSVSPTQQEVLDTMARSHKTSLQL
VETLLDVYRNDIEGLKLNLAPVDLTNLAEDVASSLIALAANRRVHLSVSY
GNSDWRHALWVQGDTLQLQRVFNNLLVNAINHSRRGAKVEVVLEGQASYQ
LVKILDTGAGIQPEQFPYLFERFYQGHSDRQAKGSGLGLYLSRQIIEAHG
GIIWAENRVPTGAMFAFKLPVYPFPSLTA
>Ava_2562 Response Regulator Receiver Signal Transduction Histidine Kinase
MIAEPLVQPTYVLLVDDNPNNLKVLSEAVQGCGWKALMATDGESALEQTE
YAHPDLILLDVMMPGIDGFETCRRLKANPITQNTPVIFMTALSDATDKVK
GLEIGAVDYITKPFQHEEVIARLKLHLKISHLTRTLEQKVQERTAELTQS
LQQLKQTQIQLIQSEKMSTLGQLVAGIGHEINNPIGFISGNCSHIEEYVK
DILRLVHLQQQKLSHSDPEIEELVEEIDLEYLAEDLPKILGSMHQGIDRL
KDISLSLRTFARSDISSKVEFQIHEGMNSTLMLLKHRLKDQSDRPKIEVI
KEYGTLPPITCYPGQLNQVFMNIIANAIDAFDDLHQKFSDQEIKASEPHT
ITINTSVDQEQASVTICIEDNALGIPPEVQDRIFEPSFTTKAVGKGTGLG
LAITQQIIVDKHNGQIKCLSTLGKGTKFIITLPISSQ
>Ava_0307 FHA domain containing protein
MTGKNARHNAFLRLVSGNGAAFGSESRYSLTSKEVVIGRDPSCQVVLDAM
MYRMVSRRHAVVRPVASSVDSKFSWVLCDLNSANGTYLNGQRLYGCQELH
AGDRISLGADGPQFLFEYAVAPQPTIITNQVAPLPSAKHPPKPDSVSFTQ
LFPIISTGKDLTRKAYLVPGILTVVFVVLMFATVGRPQANQVIVATYIAL
AAYYFIYQLCGKPKPWWVLVGAALSTTLILLSPLLNLFIFIFREVLPGSV
PPIDQPVSSLTELFVGYFFGAGLMEELLKALPILGVYLIALGLPPAWRER
VGVWEPLDGILLGTASAVGFTLLETLGQYVPAASLQAGTEVGLQVLIARI
LGLPAGHMAYSGYLGYFIGLAALKPRHAKQILAVGYLSAAALHALWNTAG
HSNNLLLVVVGVLSYAFLMAAILKARALSPTRSQNFATRFLDPK
>Ava_1851 conserved hypothetical protein
MEHWQFLIQKQGDRSWHALESPNTEILEGRYRVLARSSLPNQDVEVRVTY
FSPQEVPPKRRIQKRLRRTNSEGLMAVIPFTYLKPGIWELRCSGDLISDI
LGKSWQYGVHLQVNSQDADEVEQKLEIENTLEIDSFHQPDSASDENLTSN
SVPQLTITNESYFLSTGLSLDQESTAIDEPVSPVWVKGETAEQILQNLID
LALPTSELLLEETKIDDSPTSEPSLPLLLTLDRETYITRWGHLLTIHGNV
ALQKNLEQADKTVNTENLQALELRIELRSPLSSGILTQLRQSLGEKSLPI
TIRSVIDIPADCESKLILADIKLYGVMSYAMPEAKANPGEVTLLASHSFT
ITADVADLLAVKNVVKASPVDEQNDIMSGISTAEPPTSLDLELFNLVKTS
SPRKLQPIIPSVNTPLPGQIDPQSLNKSADFRLLQLPKLPDNPTDGIVPA
DLVTEVTLELPSLEQDDTTVPQAPAPINLDQLLIKARPSRVLGSTLPYLK
RLPTEPSSSEVKTSQIAEELIASVVEELPQVDNSITEPESNLEDVLSDIE
VNDEVVAELESQPMTEVIETLEADISVTESTAEPLTEFIDENVSAISIAP
SLPYSSPLIRKWMERQGYSFPEDDFPQEQTPPEEPAIISLNPEETPEFED
TSLLDVPAEAVETDLITLEETENQMSVEIENISPESSVLQVELPSTEPTY
TASSWLAQEFVVDDSDSEPELQTNKHQLPKTEQQEIANTIDSPQEILEPL
PIPQLYVPDGELIAGTLVRMRVELPQVSPQVVVKLWMEDCQTRWLLDGPH
LLKELLQNSSGNLEVMTQLNIPFGCMEMRIEAIALNTATQQESHKVTIVK
TVIPPDLPNMSLNDLLGM
>Ava_3975 Multi-sensor Hybrid Histidine Kinase
MKPLVSNDSISIKSHPRQQSSRNFLIRFILGGTTLIVSISAYFSYLAAHN
MALADIQKNAFLEVQTGVDQIEAWLSVRKVEVKTLANTPAVRSLDWAVAE
PYLKTEVKRIKEFFLFQMSIADGSYYTTKSGRANNNVKDREYFQQGIAGK
SSVSDPFISRSTGIPLIAIATPILSTSNSPIGVFHGSVKVDHITKVINSL
TYGKNSYAFALNSQGEAIVHPDATLMSTTEKPAPSLLKINNHSLQAIAQR
MVNKQQGIELMAIDGKQKYIAYVPLKATNWSVALVIPRENIESRLQFLDL
IALIVGGLTITMITVLWRVQAFEQAQLKKSKEAADLANHAKSEFLANMSH
ELRTPLNGILGCAQILQRSSKLPEQEQHHINIIEQCGSHLLTLINDILDL
AKIEAKKLELHGEDVHFPSFIQGIAEICQIRAAQKDILFIYEPASNLPTW
VHIDAKRLRQVLLNLLGNAIKFTDHGQVKLKVETIEESSNQKPVNHRIRY
CIEDTGIGITDAELSKIFLPFEQVGEKKRQTEGTGLGLAITRQLVQMMGS
DIHVTSQVGKGSTFWFELEIVATNEWLQSIMTTSVRKIIGFEGNPRRILI
VDDRWENRIVLNDLLQPLGFEIVEAVNGQDGLEQAIAISPDLIITDLLMP
EMDGFTLIQNLRQMPQFENIKIIVSSASVFESDQHRSLAVGGDDFLSKPI
QADELLRQLERHLNLVWIYQPSESENQAISDVVTQNNSPSAQLITPQAEV
LQELMALAKKGNFNAIIKCADQLEAEDTNFATFAHQLRQLARQFDEDAIL
DFLTQYEVEMA
>Ava_2419 Response regulator receiver domain protein (CheY)
MATKRILIIDDEYDIRAVAELAFKAVGGWQVSTAASGSEGVAKAAAEQPD
VILLDVMMPDIDGIATFQALQANPVTQSIPVILLTAKTQTAEQRGFAELG
VQAIITKPFKVMKLPAQVAAALNW
>Ava_4686 Predicted signal transduction protein containing EFhand domain
MTTEQELQSLFNTLDRDQDGKISINELFLSPGLSAVISSETNTNSPQELL
VQYDSDQDGSITFEELKKAVKKASNLT
>Ava_4568 UspA
MFNKILVAVENTEMGKQVFERGLSLATATNAELLLLHVISPFDEDYLTAG
EMETQSSYGTSQVHSVEYYVGKWNALKQEGIDFLTLFTNQAIAQGVTADF
TQELGDPSRLICEIARSWNADLIVLGRRGLHGLSEFFLGSVSNYVLHHAP
CSVLTVQGIISATPETTETASTI
>Ava_3526 Histidine Kinase
MLASQSVKNGHDLSLRLDSTLQELPVWDVEVEIHLPGNKLIRCFEHEPLL
PGVILTDHQQVVGMISRQSFFECMSRPYSFGLFSMRPIESLYNFLKPQVF
IFPAHQLVTEATQEALQRSPRLVYEPILVKSSSGKYKVLDFHQLLLANSQ
IHALTLEKLQHVKKQSRIAKAGFRDLQNNYTQLLQNEKMAALGQLVAGIA
HEVNNPINFIAGNLVHTIDYTQQLLNLINLYQNNYPHPVEEIATAIAESE
LGFITHDLPNLLTSMRSGCDRIVQIIRSLRNFSRLDESDRKLVDIHEGID
STLLILQSRLKNPNITHPINVIKEYENLPLVDCYAGLLNQVFMNLLSNAI
DALEESTVKYPGMVTKPQIIIRTEIIGDQQVVIRIADNGIGIPEEAKQRL
FDPFFTTKPVGKGTGLGLSICHQIIVEKHGGQMDCVSSLGQGAEFIIKIP
LKFQGVGK
>Ava_3171 Histidine Kinase
MLKHDSMQVSQDQPIYSEAPLQLLLFVDGRPKSKQQVQRIRAYLKDLQAE
YNFELQIIDVGQQPYLAEHFKLVATPALIKIHPEPRQILAGSNIITQLKN
LWPRWQAAVDTYVKLQEDLQERVDDNGRVAQPTSTINSVAVSAELLRLSD
EIFNLKQEKEKLLEQLQFKDRVIAMLVHDLRNPLTAAAIAIETLQSNYNP
DIGQFQRLKPALVVNLLRQARTQAKTIDKMIADLLQVGRGTDTELIIIPQ
KTEIGLLCLEVLGELRDRYTTKAQKVETDIPQDLPCVYADPERIRQVLIN
LLDNAIKYTPEGGTISIAGLHRTTQKVQFSIGDTGPGIPTDNRERIFENH
YRLERDEAKEGYGIGLSLCQRIIRAHYGQIWVDSNPHGGAWFHFTLPVYP
S
>Ava_2324 Two Component Transcriptional Regulator, LuxR family
MELVEIISVKNNARGVLSMPLTILVVDDDLGTRLSISDYLELSGYSVITA
NDGQEALTMVEVYHPDLIVTDIVMPRMNGYELVRRVRQQPPFRLLPVILL
TARTRTQERILGYQSGCDLYLPKPFELEELAAAIHNLLERSQIIQSEYRF
SQKDNSGSPLPSKIVESHHSVFTHVEKSHLLSSLTPREQEVLEMLTHGLS
NIEIGHQLHLSPRTVEKYVSSLLRKTTTSNRAELVRFAITHGLVE
>Ava_4411 Anti-Sigma-factor antagonist (STAS) domain protein
MSVHFNDEEGIIAEPLNLTVSLRGTREVRDNYQLFRLTGLLDAFSEPTFR
KVLGGKIDEGPKHIILDLSQIDFVDSSGLGALVQLAKQAQTAEGTLQIVT
NARVTQTVKLVRLEKFLSLQSTVDAAVENIKGA
>Ava_3633 Putative Anti-Sigma regulatory factor (Ser/Thr protein kinase)
MITISLRPVGRYWGTISFASTLYLCPILDLLLAEIPAKLQAELRLGLQEA
LVNAAKHGNNLDPSKTVVVRFSLIDNQYWWVISDQGQGFSPITSHEEDPT
DYLPPDESENGRGMCLLHQIFDQVEWNRKGTELRLCKQMESRPRLSLRR
>Ava_3868 Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)
MVFTRGKVYKNHLDLQKNKGFPTPTKDSISECEAGNSDFTPEFQSYEKSI
LDLQEIINLLAEINPFPVAIIGLESHQILFKNKLVDNPVLQQLIPDFLAD
SDLWTQLNSKLVNGNFIRKLALEIKSSNENRFLAIISGKLVNYEHERAAF
LVFTDVNTVIGASEEQQKDTLEKPELSNLITDTSDSQRLPTIKHSPWPAP
SHLMEQALAAISNGIVLTDANQPDNPIIYVNQAFEAMTGYSAGEVIGQNC
RFLQANETDQLSLSELRSALQEKKECHVVIKNFRKDGTEFWNELYIAPVF
DSCGQLTHFIGVQNDITHHLQALETLQEQKEQYRRIVETASEGIWLLNEN
NETTFVNQQMASMLGYTIEEMLGASLFSFMDAEGLDIAQDLLLGRQQDIQ
EKHNFKFRCKDGSDLWAILSCTPFLDEQGNYTGALGMLTNISDVYDELRL
RKQAEASLQESKERLDGILNSLEVVIWSIAADTFEMLYLNSAVVQVYGRS
VCEFYDNSKLWFELIHPEDQQRVSQSIKPLLANGSHELEYRILRQDGQVR
WLYNHSHVIYDAVGQPIRIEGVATDITERKNMEERLVYHAFYDDLTGLPN
RVLFMDRLAQTINQAKESPNDLFAVLFLDLDRFKVVNDSLSHLVGDQLLV
SFAQRLQSCLQPEDTLARLGGDEFTILLSHIQSIDDATRIAEKIHQALKL
PFNLSGYEVFTTVSIGIALSSNDYVQAADLLRDADTALYCAKEQGKAWHI
VFDSTMYDRAVALLQLETDLRWAIARQELYVVYQPIVSVATGKITGFEAL
VRWEHPERGLISPVEFIPVAEETGLIIQIGQFVLRESCQQLKQWHLEFPE
FQHLSINVNLSGKQFSQPYLVEEIEQLLQEFELDANSIKLEITESAIMAS
PEQAATILQQLKTLGIQLCIDDFGTGYSSLAYLHCFPIDILKIDRSFTKR
IDSDSEQLAIIRAIVTLASNLEMSVVAEGVETVNQLVQLQLLKCDQAQGY
LFSKPLSSDKVSLLLAAKTQY
>Ava_3306 Metallophosphoesterase
MSQTSQRRIVIGDVHGHYEGLITLLEAIAPGGDDQVYFLGDLIDRGPHSS
YVIDLVRDNNYLCLLGNHEQMLLNILSGDISVATTQAWLHSGGHATIASY
PDQSIPKEHLEWLRSLPTYIDLGDVWLTHAGLDPNLPLSEQTAEQFCWIR
EDFHSIPQPYFPDKLVIIGHTITFTFPGVNPGELAQGQGWLDIDTGAYHP
RSGWLTGLDITNNLIYQINIFTNCLRTLPLEEGVITVDHKKIAVRSSKQR
A
>Ava_4885 PAS/PAC Sensor Signal Transduction Histidine Kinase
MTDNLVTIDKNTYDSLQQELIGLRQVVAKTLQLGLLIEYIPAAIAIFDSE
MRYLLASRRWREDYDLVDENIVGRSHHDVCPEITLGWQNRYECCLAGNTE
KSEEETLIRRDGTIDWVKWEINPWYEPSGEVGGLAVVSEVITPRKQSDIA
LADSERRLRDTEARLQRLADNLPGMLYEFCLKPDGTMTFPYVSSGCRELI
ERSPQELQDDASLIFANTHPEDMIGLQEAIANSAKTLQNFEYEWRIITSS
GQIKWVQGVSRPERQPGGEITWYGYLLDISEQQAVLRERKQADQQLQQQA
QLLQSIWEGVDYGICVLDVLDDEAEFRYVKINPAMHRISLLPVASFIGKT
TAESLPPEIADLYRQRYQQCIKSRKSLVFEDNFLVNDKETWWFVNITPLG
DSNSQISQLVVTATEITERKQAEQERQLFVSLIENSSDFIGFATLAGKPL
FLNEAGLKLVGLDGLDALKNLHIMDFFFPEDQEYMDKHIMRVVNERGLWQ
GEYRFRNYQTHEEIPVDFNIFTVKSSETGKPLCLATVTRDIQERRKVEAL
LQEQEQFLRNIYEGVDQIIFVVDVLENLDFCYTGWNSTAERYTGITRNDA
IGKAPEDIFGSVEGSLVRQRYKNCVEAGVSISFEDCLTFHNQETWWLTKI
NPLKNSAGRVYCLVGTTLDITQRKQNEIQLRQQAENLENTLRELQLTQTQ
LIHSEKMSSIGNMVAGVAHEINNPVNFIHGNLIPASEYAQDLLQLVELYR
LHFPYPPEEIQEFIIDIEFDFLKEDLVKLLQSMRIGTQRIREIVLSLRNF
SRLDEAEFKQVDIHEGIDSTLMILQNRLKAKSDHPEILVVKSYGDLPLID
CYPGQLNQVFMNLISNAIDALEEPVVDGQLSVAKPTIYIRSEMFNNNWVR
VTISDNGVGIPQEILSKLFDPFFTTKSVGKGTGLGLSISYQIVVDRHNGK
LTCNSTPGQGAEFIIEIPIHQ
>Ava_3003 Multi-sensor Signal Transduction Histidine Kinase
MEPVKILVVEDEVIVARTIASQLNQLGYIVIGTASSGKAAIAKAIETSPE
LVFMDIILKGEIDGITTASYIREHLDIPVIFLTAYGDDNTIERAKITQPF
GYIVKPFTSKDLRISIEMGLLKHRLERDIRENRDRLATLLNSISDAVIAT
DEFGNVTFMNPAAEEITGWHQADAIGHEVSQIFNIIDEVTENVLENPVTK
VLREQKVVYLDEYTSLITKDGRRVPIGDSASPIMGLPNKINGVVIVFWDL
SERRQTELLEQALQKERELNNLKSLFISTVSHEFRNPLSVIQTAIELIEL
HGQNLTETKKNTYIKRIKGAVQSMKLLMEDVLFMGKSDAAKLDCNPVLLN
LKGFCQELIEEFTTVEISGHEIIFTCSDETTNAFMDERLLHYIFVNLLSN
AVKYSPQNETIRFDLTFDQTKGVAIFRIQDEGIGIPVADQTHLFESFYRA
SNSQSIQGTGLGLVIVKRCVEAHKGEIAFNSQEGVGTTFTITLPLNCQ
>Ava_0305 FHA domain containing protein
MPSLNLAIARLINTGKDSFAIWVVKAPYPSGYVLRDCAWPAELSQIWQEW
QQMFAGHSGIHISSDTKPPLTNSVPGNIVSLPSGQTTGYSSRLMQYLGMN
LWRWIFEGPILGSLERSRGIAMGQHTRLRFRLEIRDPDLIALPWEIMQRE
PGQPAVSLSPDVLFSRTTSEVEALPYLRIDQALKVLLVLGHDQNLQLQTE
AAILEKTLLNGGQVAGYGQGYAPCTVKTLIQPTPQELIQELETKAYNVFF
YAGHGLPGPDGGLLFLRPGMSLNGIELAQVLTRSALKLAVFNACWGAQPA
AINHQAIPASSLAEVLIRHGVPAVLAMRDEIADHESHSFIQAFAEALRSR
KPIDEAVAEARQELLTLYKYNQPAWTLPVLYLHPDFDGELIKSFDESVTE
MPDTAIPNSNSSMPIASLRSLSPGGRSWFLRTGVTRIGRTKDNDIVIPEL
SVSKRHAEILCRNNFTGNPARTYYLQDFSTYGTTWFLGSNGWQQILREEV
PLKSGMQLKFGSSRGEIWEFIIEDS
>Ava_2149 Response Regulator Receiver Signal Transduction Histidine Kinase
MSSPINNSVLIVDDIPTNIKVLFDILNQAGFRVSVAKNGLSALAKVQETL
PNLILLDVMMPGMDGFETCRHLKANPKTKDIPVIFMTALSDTVNKVKGLQ
IGAVDYITKPIEYEEVLARINVHLELRRTQLKLAQEEKMSSLGQLVAGIA
HEINNPVNFIYGNLTHAQNYVGDLLNLLKLYENHTVNPSPEIQAFSKSIE
LEFIKQDLPHLLSSMQMGTERVEKIVRSLRLFSRLEDPEFQLFNLHEGID
STLIILSHRLKILPTDSTIHIIKEYGDIPLVECYSGKLNQVFMNLLANAI
DALEESVVNRETTDTLTIWIRTTVVDDQKSVLIEITDNGVGIPLEVQQRI
FEQFFTTKPLGKGTGLGLAIAHEIIVEKHGGTLQVQSTPGKGTQFLITIP
IQQVIRY
>Ava_0478 conserved hypothetical protein
MVEPLFWLGLSIVLVATSLTAVLVAAIPALQELARAARSAEKLFDTLSRE
LPPTLEAIRTTGLEITDLTEDVSEGVKSASQVARQVDQSLDGARKQAQNL
QVGTRSIFVGVKTAWKTFTRQKPTRRAVERLSITEPSSFALREREALKSE
NRLPKAEVYRSHDGYSEASNWNNGIDDEEFL
>Ava_B0028 Histidine Kinase
MQQEHLSKQLDLLALLHDVSNNHQGASIVLNQMIAGAYGQSLEEIRPFLI
SLQELNERVVSLIQSRKTTFFEVNPMTVTQFDMLAFLQKTYCLFNPIAQY
HSLKLHYETQTLYKHGTQVRADGVSIDRMICNILTNAIKYTSRGEIFLRL
LHQCDDLIIEIEDTGIGIAAEQISNIFLPLWQSPNSSNRVGMGLGLYIAL
SVAYAHGLDIKVNSTVGQGTKFTIIFPYKDDGIYGLDGRMLPKSQKVQDA
LPI
>Ava_C0156 Multi-sensor Hybrid Histidine Kinase
MRLSQNTTPAATETEVLITEELAGRPTRQADLADENQALHTLSQHLSDEP
QLLLKTLVRIGLELCQADSAGISLLETQSNGESRFRWVAIAGALEFLEQT
TTPGNFSPCGTTLSAKQVQLYTYPERYFTYLHHPLFPIVEGLLIPLYINN
QPLGTLWIVSHQETRRFDGEDHRLMSRLAGFSASALQSLNYWHQKAENAV
RQEQAIRAKLNYTQAQFEALVANVPGIVYRYSPCPDHPYRFTFFSSGCYE
LLELEAQTIVQDGNAFVQLIHPEDVDSFKSSVTHAVENFLPWRWEGRIIT
PSGKLKWIVGSSRAVPTTEGNAWDGILIDITNHKLAEAELRQSREEAQAA
NRVKDEFLAVLSHELRSPLNPILGWSSLLLKRKLSEAKIEEGLATIHRNA
QLQSELIEDLLDVSRILRGKLNLNCSPVDLTATIMGAMETVQLAAQAKSI
TLQAALEPNIGQVRGDATRLQQVIWNLLSNAVKFTPPGGQVNIHLEQLGN
VVQITVSDTGKGIAPDFLAYIFDYFRQEDGSITRKFGGLGLGLAIARHLV
ELHSGTIEAQSPGVDQGATFIIRLPLMSPQPTTTQDSKLSDLSIDLSGVK
VLVVDDEPDTRELVAFVLEQHGASVTAACSAQEALTILNQSNFDVLLSDI
GMPNIDGYMLIQQLRNLWPQYRQIKAIAFTAYAGEINQQQALKAGFDRHI
FKPIEPLTLAQAISDLVRST
>Ava_2791 Serine/Threonine protein kinase
MAYCINPDCSQRENSDTSAVCQNCGTPLILQNHYRLRHLLQTDRRSYTEV
FEIEDLVNRDQPKVLKSLKEVTPQLERLFQQEASILQTLRHPGLPIGEAL
FPLVLNTGRQLWCFVMEKIPGEDLQTWLSHHQYVTSYKTALDWLKQLMQI
LQFVHQEKFFHRDIKPANIMVCPDGKLVLIDFGAARKVTQTIINREPVTI
INSLGYTAPEQRDGHAVVQSDFYALGRTVIYLLTGIDPTGDRVQDLLNWS
KYIQDPKTPKKFISLLQAMTDSYPHHRPPTAQAILAKIENIEQHSYPWPK
LLLGAACGLLLLFAGKSLYQEITLPRTCDNILNDYLSCGEESLTPSSFWG
NSQPPPAKQLGMEEYRHQNFEAAVKFLETAFQQESDPETLIYLNNSKIHQ
QFPVNQIHTIAVAVPLERRTDIGREILRGVAQAQTEALKQGRALRIIIAD
DSNREDSRTGNNARKIAQQLVKYPDLIAVLGHYSSEATKNSLPIYRQAGV
VLISATSTSQNLKDPFFFRTVPSDRIAAQKMVTYLLSELKQNQVAIFYSQ
GSEYAESLSQAVRESTKSLPLKVIDHQAAFNLASDRFNAITALNQAQTQG
AKAIVLIPDAGVGLYNAIPNALRVIQTNINQVWIVAGDSLYSSDSFKSEK
VFSSPEIQYTAWAVFWHPLNEMNSTFVKEVQNLWKIDLSSLLRNTDITWR
TTTSYDAMLVLSQAITQNPTRLGIQKTLSQPQFSVTGATGVIQFAGSDRQ
NGKITMVRFQRNCDDNGFVVIPSDRSLQCR
>Ava_4095 Metallophosphoesterase
MRTIVVGDIHGCYAELLQLLAKVEIAEEDCLVSLGDIVDRGIDSVKVYDF
LKNRPNTIVLMGNHERKHLRQTLSYSQEIVKLQFGDSYDEFLEWISHLPY
YHETESAIFVHAAVEDGIPIEEQREEVLCGCTAGEKHLGKRYGDSSWSQL
YTGVKPVIFGHRVVGDHPLIIPQKTYGIDTGACHGGTLTAIILPSFEIVQ
VQAAKDYWQEEIVKWQLPVMKAKPWGSYKWEKIQAICDEFRNSANSELSA
FIAQKEQWMYDLLALAPKIILKVEEKLAELISVYGNDGFKKPARCFTYAT
LLYQANASNLTSKFLQQALPTPDKWLQIMKELEV
>Ava_1029 Multi-sensor Hybrid Histidine Kinase
MNRQHKHHRCNPVNFLSKQNLLPFLLGIVILLVVVMLWLRLQAEEEIKIQ
QLIKQQAIATQTELVTQLKTRILALKRIGKHWEMHGSIPQAQWELEARAY
LEDYGGYQAIKLVDPSWQVLRSVSVAKNKAAENLEIMPKFPQCKGATAQP
SHETTLTHTVNLNQGDRVFFACVPLWMGDKFGGAVLGIFQVKQFFESVLH
IAPGYKIRVFDGQELIYGQDRQSSTLPSWQQSVNINFDGMTWQLQIYPTP
ELLKDLYSPLPTVVLVAGIFNAGAVTLLIYFAQATKLSNHQIGRINQELA
DRIEKQTQVEIALRASENRLRELLETVRVIPWEVDLKTQHFTYVGPQAET
LLAYPIAQWYEENFWDNHLHPHDRDWAVRFCQEAANKGQNHELEYRMLAA
DGRVVWLRDVVNVVEVDGTPVMLRGFMFDITDLKRVEETLRLRERALAAS
SNGIVISDAKLPNYPVIYVNSAFEQITGYKATEIVGRNCRFLQGNDTTQP
AIEELRSALKAGKNCKVILRNYRKDGSLFWNQLSVSPIYNDNGQLSHFIG
IQTDISDRQQAEASLRRQALTFENIYDGVIITNLQGQILDWNPAAERMFG
YSKDHICGQSISILHKVEEDAALNSAIIAEITKQGRWSGEINFVRQDGSQ
GICETTIVALQDDQGQTVATISVNRDITERKHAELLLRRSEERFQAFMNH
SPTPAWITDIDGTIVYLSETYRRTFQLPTQELIGTNIFDIYPPELIQTFR
ETIQIVARTHQVMETVESVPCSDGTVRDFLVYKFPISSKPDECLIGGIAI
DITERKQAEAALRKSEERWQLVIEGNQDAIWDWNIITNETFRSARWAELI
KEQNYQPIADHADCISRIHPDDYERVMAVRQDCLSRKIPNYVVEYRLRCN
DDSYKWVLVHATGQWDERGNPVRMVGSIKDITERIEAQEALQRQLHRTLL
LEKITQKIRQSLDSKEIFETAATQIGQALAVDRCLIHSYISHHDPHIPLV
AEYNNVLDYCSMQKWEFTTTGNRHILQMMSQDKAIASANVYTDPLLQTAV
PSCCEIGVKSMLAVRTSYQGEPNGAICLHQCKYFRQWTPEEIELLEAVAA
QLGIALAQAQLLEQETRQREELTIKNFALEQAKRAAEAANRAKSEFLAMM
SHEIRTPMNAVIGMTGLLLDTELTSQQRDFVETVLTSGDALLSIINDILD
FSKIESGKLELEEQPFEVRTCVEQVIDLLAAKAAQKDIELAYLIHPQVPM
QIAGDLTRLRQILTNLLNNAIKFTPEGEVVVSVRSQPSPNQKTKNCCEII
FTIKDTGIGIAPETMDLLFQPFVQADASMTRKYGGTGLGLVISKRLGEMM
GGYLWVESRGCVGGNPPPGWQRKNSISSASVATGSTFYFSMTVPVVAHAD
LETSITSPVQLSGKRLLIVDDNPTNRQILRLQAEPWQMETYTAPSGAEAL
ALIDQGMAFDIAILDVQMPEMDGLTLARQIRQRPSYQHLPLVILTSWGQP
DTDLSDIEFAACLNKPIKQSQLFDVLAASLGNQPIRASVVPDRSAQVNSC
LAQQIPLRILLAEDIVVNQKVALLILKKLGYRADVVANGLEVLEALQRQS
YDVVLMDVNMPEMDGLKASQIICQTWSPRSRPYIIAMTANAMRGDREACL
AAGMDHYISKPLQLEELAKALGKCHPSTSSTEKALEKTSSQNQTFTDISD
LKFATIDTKILQALRDMLGGDKVAFAELINCYLTESPKLIENLNVAINTE
DTQGIWKTAHKFKSSSGSVGAVFLAQLCKLLEAKGRNNNLEGCIELGSQL
CQEYELVKTALYREVNKETP
>Ava_0301 Two Component Transcriptional Regulator, LuxR family
MSAQLLLVDDEPGLREAVKDYLQESGFSVQVASNAREGWDLMQQSTPDLV
ISDVMMPQVDGYQFLKQLREDPRFQSLPVVFLTAKGMTSDRIQGYQAGVD
AYLPKPFDPDELVAIIENLLTRRNSKPPKTTEEGETPDIAELANQIAQIK
ALLTQRNAISQSPAPFKIDLTPREQSVLNLVAEGLMNKEIARRLETSVRN
VEKYVSRLFSKTGTNSRTELVRFALEHGLAK
>Ava_0740 extracellular solute-binding protein, family 3
MFMNKLVIILGASLIFTTTACGGDSAPTTDASTNSGGTLVANRWNTIKNR
GQLICGVSGEVPGFSFVGTNGEYSGIDVDVCRAIAAALFDNPDAVEFRNL
SAKERFTALQTGEVDILSRNTTWTLSRATSVGLEFAPVVFYDGQAIMVRK
NSAIKSLADLKDKAICVQTGTTTEQNLADQMRKRNITYKPVVFEDVNVTF
ATYAEGRCDAITADRSALVSRRTTLPKPEDNVVLDEVISSEPLAPAVAKG
DAKWSDTVNWVVYALIKGEELGINSQNLGQFTTSNDPDVKRFLGTEGDLG
QGLGLTNDFAARIIKHVGNYGELYDRNLGPKTKLNLARGQNQLWSKGGLL
YSPPFR
>Ava_4504 Serine/Threonine protein kinase and Signal Transduction Histidine Kinase (STHK) with GAF sensor
MSATVDTTVLLSGYQLIEQLYHGSKTLVYRGIRRKESVAQPVVIKLLQRD
YPSFSELLQFRNQYTITKNLNIPGVVRPSSLEPYGNSYALVMEDFGGVSL
GTYSQTHSLSLVDVLAIAIQLANILHDLYQNRVIHKDIKPANLLIHPDTK
KIQLIDFSIASLLPKETEAVKHPKVLEGTLPYLAPEQTGRMNRGIDYRSD
FYAFGVTLFEMLTGQLPFISDDPLELVHCHIAKPAPSVCALRPEIPSVIG
EIIGKLMAKNAEDRYQSALGLQYDLQNCLEQLQNTGKIEAFEIATRDICD
RFLIPEKLYGREEEVATLLTAFERVSNGNSELMLVAGFSGIGKTAVVNEV
HKPIVEKRGYFIKGKFDQFNRSTPFSAFVQAFRDLIGQLLSESDEQLQTW
KTQLLQALGENGQVIIEVIPELERIIGEQPPARELSGNAAQNRFKLLFQN
FIHVFTKPEHPLVIFLDDLQWADSASLNLMQGLIAESKIGYLLLLGAYRD
HEVYPAHPLMLTLEAIEKTGATINTITLQPLSLTSLNQLITDTLNCTATL
AQPLTKLVNQKTQGNPFFATQFLKALYQDELIYFDLVTGYWQCDLVQVKA
AALTDDVVEFMALQLQKLPPVTQDILKLAACIGNQFDLNTLAIVSEISPA
ETSTILWKALQEELILPLSETYKFFQSSPHQTTGDCQITISYKFFHDRVQ
QAAYSLIPQEQKTATHLRIGQLLLTHTPETELENRIFDIVNQLNVGVAYL
TDQPEKQRLLELNLMAGRKAKVATAYVVAVDYLNTAIKLLEEDSWQNQYE
LTLSLYDLVAETEYLNTNFPTSELLVREILVNAKHTLDKIKAYEIQIQAY
TAQNKLIEAINIGREVLGLLGIDLPEDGNIETIITEHGRLKSLFGERLIE
DLVNLPELTDLQQGAALRILCGLFAPIYLAKPMLLPLKIFTMVKICIQYG
NSPQSAIAYSLYGLFLCASEEIADGYQFGQLAMTVLDKFNAQELRSKVYL
TFALFIKHWQDSINSTLNIFLEGLKSGLDTGDLEYVGYCANCYAQFLFWT
GQNLEIAEAEANKYCALMQDLKQDVSLIWGNTWRQTVMNLQAKVDNPQML
VGECFDETVTLPALISSRNTNGICYVYLAKLFLAYLLGADEQAIKYASLF
EEYEQGAAGLLIVPLKNFYQSLSILSLYPKLDTEQQSRHLEKITNNQQKM
QNWADHAPLNYQHKFYLVAAEKHRVLDEKTAAIELYDQAIALAKTNGYIQ
EAALANELAAKFYLDWGKEKVAAAYMQEAYYCYAHWGSLAKTNDLESRYP
QLLRPILQQVIHPLSILETFASLTSSVHSTRHQSSSSTSINHMLDFAALL
QVSQAISSTIQLDKLLQTMTETVLENSGADYCALILCQEGEWQVKVIANS
QQTSLQSTPLENNPTVPVKLIQYVKNTLETVVIHDLKTEIPGVMSNYLDQ
HHPKSVLCLPLVNQGNLSAILYLENQVTSDVFTSDRLLVLKFLSSQAVIA
LENARLYHQVQKTLEDLQQAQVQIVQSEKMSALGNLVAGVAHEINNPVGC
IVGNIGAAQEYINDLLGVIDLYGEKFPQPGTEIEDELQAIDLEYLREDLP
KLIRAMKDGSDRIKAISESLRTFSRADSDQKQPFNLHDGLESTLLILRHR
LKANQYRPAIEVITEYGNLPLVKCFPGQLNQVFMNILANAIDALDESNPG
YSFTEIEANPNRIIIRTTVAGEQIKIAISDNGHGIPEEVKAKIFDHLFTT
KGVGKGTGLGLAIAHQIIVEKHGGAIAVNSQPGIGTEFLLTLPIS
>Ava_1558 Two Component Transcriptional Regulator, LuxR family
MSEISIILIEDHDLTRMGLRAALQANTGIKVIGEAANATQGLKLLETAKP
DVAVVDIGLPDMDGIELTRKFRRYQAESGQTHTKILILTMDHTEDAVLAA
FAAGADSYYMKETSISRLTEAIQATFGGNSWIDPAIANVVLQKMRQGIPG
ESQSSDKPKTVKIEALPSEYEQVLETYPLTQRELEILELIVAGCSNGQIA
EKLYITVGTVKTHVRNILNKLCADDRTQAAVRALRSGLVA
>Ava_4782 CheB methylesterase
MSYKIVVIGTSLGGLSALQTVLGNLPADFQLPVAIVQHRHKDSDGTLRGM
IQESILLPVREVEDKDEILPGQVYLAPADYHLLVEPGYFALSTDEPVSYA
RPSIDVLFESAADIYGEQVIGVILTGANQDGMQGLKKIKAKGGITVVQEP
STAASAIMPTAAISAVTVDWIVSLAEISPLLVNLGYSTRK
>Ava_1279 Anti-Sigma-factor antagonist (STAS) domain protein
MQAVLKCPKIQVIRPYGCLNATNALEFEQDLTKTLAKEDISSLWVDLADV
ESLDSSGLMALVSALKIAQNLGKGFQLYSVSPATRIIFELTQLNEIFEIF
EHEAELVVGQLY
>Ava_3207 Histidine Kinase
MSQEFCPLVSPPTVSRGSDRDLGLDSTIQELPMYTFQVEISLTGVEVAKY
FDKYPLLPGVILLEQGKFTGMISRRRLIEFLMRPYGQDLFAKEPLDVLYR
YARLAVLVLADTTPILTAMQQILRRSPEFLAEPLVVQTADNSYRLLDPHE
LNIAAWQIRGIETQVRYERSQAQMIQNDKMARLGRLVDGVAHEILDPVGF
IWGNLTYISNYSQDLLKLIAAYDECLPSGCEVINDIKEEIEFDYLEKDLS
KALTSARSGAERLKKLVTSLQNFCHIDAVYPKPVDLHASIDSIVILIKSR
LKGEITIIKNYGKIPPVSCFIGQLNQVLMNIFSHAVDSLLDETVRRQLQP
DCGQNVKQATIEITTEVISQAATKPNEFDSRWVSICVADNGTGMSEELQQ
QIRENFSIEKRTEKETSLAVSYRIITARHGGKLNFSSKLGIGTKFEILLP
LL
>Ava_0774 extracellular solute-binding protein, family 3
MTMYKNLAIALFSLTLTTVIPDAAFGETVMQKVARTGVLTAGTSRDAMPF
AYTNAQGQLTGYSVDMLSVIKQQLEKELGKKIQLKLVALTPAQRIPKIVN
QQVDIVCDASSFTWERDKKVDFSVSYGATGTQLLVKSGSNLGSPESLIGK
RIGVLAQTTNEQAIKRVQPQAKLVYLKSRSEGYTALQEGKIDAFSSDSIL
LESWLQKAKNPDDFAIVPDRPYSREGIACMVPENNSKFLDAVNYSLVKFM
QGFVNGDTRYVTTFDRWFGAKGVVLLNRDLRDLMKETMQLFIEFREEIPQ
QEL
>Ava_4870 Transcriptional regulator/antitoxin, MazE
MTAVVAKWGNSLAVRIPKSIAEQAHITEGTDINFSVEGNSIVITPKRRKK
YTLDELLEGMTPDNFHPEFETGDAVGNEAW
>Ava_1030 Putative diguanylate cyclase (GGDEF domain)
MKNTVPESPSLILIVDDEPFIRAQLRLSLQCEGYRTAEAEDGRKALTIFQ
ELQPDIVLLDAIMPDLDGFECCTRLQLLEDGKYTPVLMITGLEDQESVDR
AFEVGAIDYVTKPIHWPVLRQRVKRLIQQSHLQQKLEAANRELQRLVTID
ELTQVANRRRFEEYCAQEWQRMARDQLPLSLILCDVDFFKAYNDTYGHRA
GDRCLQLVAKAIENCVNRPADVVARYGGEEFAVILPRTYPEGAIHLANAI
CSAVRELQIPHLTSQANTCVTISAGVATEIPVPNSDFQEIIDAADRALYQ
AKMAGRDRCQQYIKQSSSPVYFLNAHHRLA
>Ava_3187 Transcriptional Regulator, Crp/Fnr family
MTVTERILEVKQFLQKTPIFRDLLDEQLQALANIAIVQTYKKGEIIFWEG
DEGTGFFIVKSGRVKIFKVANGGKEQIFHIFGAEEYFAEVPAFDGGNYPA
SAAALENSQVVFIPRSSFLTVLQQHPTLALAILGTLARHLRKLTHLVDTL
SFQEVPQRLANYLLNLSKRLGNADVVELDLPKGQLAALLGTIPETLSRAL
YKLAQEKIIEMEGTTVRLCDRDRLINLQNKK
>Ava_0059 Response regulator receiver domain protein (CheY)
MSITLVGKILIVEDSPSELELMSRYLQESGYDVIKAAGAKEAIEKALLEK
PDVIVTDVVMPGMSGFELCRSLKKHPLTEKLPIVICSSKNQEIDRLWAMK
QGADAYITKPYTRENLLRTIKSVVL
>Ava_1021 Histidine Kinase
MIPQSLMSMLQYPLDEFLANVTSCLETSTLAMVLEVFEQQQCDRLPPAFG
DRLVIVNEQQCPVGLLHSGQLARKLLAATGNELFLNLQQPLSTFSQALIE
PIQILPASHSVEQLGVFWRYHQAHNWEYVLVDEEGKFLGILDSVRLLAAL
AKEQTANHSHAPNSTYAPNSTYIDGVEADLRGSPMESGTPTLHSLQDVAR
SLRDTSPASRGDQLQPLVQLLERLPWPLMLQTSAGEVLTRNLAWWQQLGA
LKDPEGVRQQVEAILAATRIKQPEYVGQRSTTGTNHIQGYEQVGEELAQI
PATGLLPLSPYEPTTSAKTSSSRCFLDSQMGTCTCVVEVQNGQERVWQFA
KILLDNTDLKLPNTDDLWLVLATDVTEQQQLCKELAAKNADLIQLNRLKD
EFLACISHELKTPLTAVLGLSRLLVDQQLGELNERQARYAGLIHQSGRHL
MSVVNDILDLTRMETGQMELTPVPVSIRAVCDRALSEAKAIHNQTSKGST
TEATRQSTPEFTLSIELDLDQIVADELRLRQMLVHLLSNAFKFTEISGEI
GLRVSHWEGWIAFTVWDTGIGIPEHQQHLIFQKFQQLENPLTRQFEGTGL
GLVLTRALARLHGGDVSFLSREGKGSQFTLLLPPSPPSSGFSESEVEVED
MPTSNTRNRVTNTGQNHPVSCQRLVLVVEAVARYIEDLTDQLKTLGYRVV
IARSGTEAVEKARRLQPKAIFLNPLLPLLSGWDVLTLLKSDSATRHIPVV
VTATGAEKEIAFANRADGFLSLPVEQQSLTPLLDKLCGKSTVQSLGLGIN
ERNQSKKTLRILRLVDVELESINPHPSLQEHRVIEVDDLDQAELLARVWQ
FDVILLDVETSLAKAYLQQLTQHPRLAALPLVTCDVETTLAASQIPGLSV
FPCLTPRVKDQDSELRKGKVDPLLSVLQIASGICYPPSIFVVDLTMLEDL
PQARRKPVKGSGTERRTVSRGEVAERGTEWFQALIQYLQTAGLKATMARC
WAEVLQQIGHNSVDLLLICLGESAIHPEAVNALKALQDLPCNLPPILVID
QQLSRTQVTSRSRLTHHKKQESESITDVAKAIATQIVPRSISMEDLLTQI
HQTLTLNER
>Ava_3382 Protein serine/threonine phosphatases
MKLNFTGHTDPGLIRSNNQDDYYIDPEGRFFIVADGMGGHAGGEEASRIA
TREIKAYLTSNWDVSKPSPELLEQALWQANEAILQDQQNHPERADMGTTA
VVVIFRNEEQWCAHVGDSRLYRLRETQLEQVTEDHTWVARAIKIGDITAE
EARVHPFRHVLSRCLGREDLHQVDVQPLDTKIGDRLLLCSDGLTEELPDQ
KIAHNLQINSLLDQSALSLVEDAKDQGGHDNITVVIIALE
>Ava_3712 Protein tyrosine phosphatase
MKKVMFVCKHNSRRSQMAEGFTKILGKDNIAVTSAGLAVSQIDPFTVEVM
SEIGIDISSQTSKPLENFHPEEYDAVISLCGCGVNLPEAWILRDIFEDWQ
LDDPQGKSIEAFRRVRDEIKERVVKLIALLN
>Ava_2684 Serine/Threonine protein kinase
MSLCINPVCPNPNHPHNDKNRFCQSCGSQLELLGRYRVTQLLSDTTGFAT
VYEAYEENTAKILKILKANLSRDPKAVELFRQEAVVLGQLNHSGIPKVDS
YFQHQTRNGVILHCIVMDKITGTNLEEWLQQQQNQPISQAQAITWLIQLA
EILDSVHGKLYLHLDIKPSNILLQPDGKLVLIHFGTAKNYANGTTTPTLL
SGYSAPEQMNGEATPQSDFFSLGRTFVFLLTGQHPLDMYDVHQNLLRWRN
YTKQISPLLLNFIDWLIAPESKNRPTNTQGILQRLRDIQQQVNWNEIPQS
EQQTQLKSHLPLQSPTKSFNKVPLIAFCAALIVSVGLLSLVAFMIGYPRF
TLLPPPGQSPQRKGKIAYFPYETGKDSQGRVAKFNIAVLSIEHKWLSGSN
FQIRNNDRVISLDVLKLRLEQEGIQEIMENPEEIISVGTASCEGSLSVAQ
RKAFERSQQIQNLVKKIFQNSPSVKNYRLLNLGEFQGSVCQSNRDLTAYQ
RSVIIIGLKRQSKAVVIDEALRNRLENKPFGDFQLDDYSLGSVDKFKTIP
SQL
>Ava_4401 Multi-sensor Signal Transduction Histidine Kinase
MRPSNNQVAKLPVHQTKAPLQIGESGKKYFNFKVSLETENNLYQVIENFH
KIIIVFTSDGHVCYTSPNVTETLGYEVIELEGKSFASFVHNDDVRLFTDY
LSTVAKSGNKHQPLEYRIKAKDGSWRWQEISTSVFKDENGNVVYFVGITH
DITDRKLTEAALAERILLANFRTAIDNVFSQNHTLQQLMRGCTETMVTHL
NAAFARIWTLNKQNNILELQVSSGMYTHIDGPHRFVPVGKFKIGLIAEEA
KPHLTNSVQTDPRVGNKEWAKQEGMIAFAGYPLIVEGEILGVIAMFSRQV
LSESTFEALRITAHEVAIGIKRKQIEEELRKSEAKYREIAQASQEKAQKL
EAALWELQQTQAQLIQTEKMSSLGQLVAGVAHEINNPVNFIYGNITHTRE
YIEDLLYLVKLYQSHYNPVAPEILDHIYGMDLEFISQDLPKVLNSMHMGA
ERIRQIVLSLRNFSRLDEDGMKAVDIHEGIDNTLLLLQNRLKAKPGCSEI
QVIKEYGNLPNILCHAGQLNQVFMNLLTNAIDALEESVASSQLSVVNSKT
TNNPRILIRTELTTENQVMICIADNGMGMAEKVRSQLFDPFFTTKPIGKG
TGMGLSISYQIVVKNHQGQLQCISAPGKGAEFIITIPTGDG
>Ava_1138 Transcriptional Regulator, AraC family
MVFDSCISEQHTYQVTQQLEKELRLTHLLMDCVTDAVFWVKPNARILYVN
DAACSLVGYSREELLCMSIQYLNLEFLMEVWLQHWETIKQKGSLYFESLY
KTQGGLSLPVQTTVTYMEEDGREYGCISIREIKKRQPESFQLQQNPTLDI
VETRKPSEPCKSIFPSGSQLNQVFKFIESNYNQSIGLRDVAQAVGYSPAY
LTDLVRRHTGETVNHWIIKRRMVAARTLLLETDQCVNQIAEAVGYQHEGH
FFRQFRQYHDTTPHAWRKMQRQVATS
>Ava_0239 Response regulator receiver domain protein (CheY)
MTNLTMNNKRILVVDNEQYIQEVAKICLETVAGWEVVTASSGQEGINKAE
TYQPDAILLDVMMPDMDGIATFEKLQANSVTQKIPVILLTAKIQASDRRR
YSQLGMVSAIAKPFNPLELAGQVATALGWNLA
>Ava_4716 Serine/Threonine protein kinase and Signal Transduction Histidine Kinase (STHK) with GAF sensor
MVISHNIQVSGYRILELAHSGANTNIYRATKVDGNTPTILKVLIDNYFSL
EAIVRFKHEYSISANLDHPNIVKVISLETHHKRLVIVFEDFGGISLKHYL
YNHQPSLQLTLQVAIAITRALVYIHDNKIIHKDIKPGNIIIKNLGTRLQQ
TPEVLSNLIIKLTDFSIASRLKKETPQLINPNQLEGTLAYMSPEQTGRMN
RNLDYRSDFYSLGITLYEMLTGQLPFNSSEPLELVHAHIAKEPTPIQQLA
ANVPNAVVGIVHKLMAKNAEDRYYSAQGLLVDLEQCLEQLNHTGAIADFT
PGRLDVFSQLIIPQKLYGRETQVEQLLLSFARVSRGNSELILVSGYSGIG
KTSVINEVNKPITQVKGYFISGKFDQFKRDIPYLSLVQAFSSLMRQLLTE
STERLEMWRSNILQAVGSNGKVIIDVIPEVELIIGKQPEVSQLSPHESQN
RFNQIFQSFIQVFCCCGHPLVIFLDDLQWADSATLNLMESLICDQTIKYL
LIIGAYRDNEVSKLHPLISTIEEIKKSGIIINNIELQPLDLANVVHFVQD
TLHDNTTRCYPLATLVFNKTAGNPFFINQLLKALHQESLLVFDFNIQQWQ
WEIEKIITVGLSDKSVVELVCSRIQLLPEKTQKILQLAACIGDNFNLYVL
SLVNEKSVFDTAHELDDALQCGLILPLSETYRIPLLFDAQDDILFDSKQI
LYKFLHDRVQQAAYSLIPENQKKYTHLKIGRLLLNNIQEKDIENHVFDIV
NQLNKSVDLVIDDSEKNRLIELNFIAGHKSQQATAYEPALSYFMMAIKLI
GESSWLTNYKTILNLYQEATEAAYLCGQFDKMQGLANVVINNAHNLQEKT
KVYNLKILTAIAQKQLQEALSLGLNLLNQLGINFPEEPTDDFVNQVLLET
NSLIPRNNIQSLLHLPEMTDVNSLAAMDILDTISTAAYSASPKLMLLINL
SRVKLSLTYGNSASSPIAYAAYALILCGVINDSELGYELGKVALDLTADL
SPFIKGKILFYVSNFIFHWKTHLRETLHFSKMGAKYSLEGGDLEYTAWFY
QFGCCSLYWQGEELSNLKQKIENANCAIRQTKQEQPLSHQYMLYQVVVNL
MDNSQDACCLIGENYNEQESLTQYEIVNDYLGIYYFHLYKTILNYLFGQH
EQARIHAGIAAQNISGATAQFVVPIFYFYDSLTQLAIYTNEAESGQQRIL
TQVQNNQEKMRKWAESAPMNFLHKFYLVEAEIYKIQGKNYQAMDYYDRAI
TLAQEQGYIQEMAIANELAAIFYSQLGRTKLAKSYMDEAHYNYISWGAIA
KAKDLEKRYSNLLTRTGTLTQSHITLTKGSTTSTRNLSLDISTVVKASQA
LSSEIVLEKLLEKLMFLAKENAGAQKVFFIAKKDEKLVIEGSLMEEGIIK
TLQAIPITNSQALPASVINYVKRTQAPLVLDDVTHAEDFNKDPYIINYRP
KSILVSPIISQGKLTGILYLENNLTSHAFTEDRLEVLQVLSAQAAISLEN
TRLYLTLETRVQQRTQELEDKNHQLQTILGELQRTQAQLIHNEKMSSLGQ
LVAGVAHEINNPINFIYGNVTHIKDYSKSLLDIIDFYQAEYPDSQETILE
IADEYDIDFIKDDMPKLLTSMKNGAERIRDIVISLRNFSRLDESAIKEVD
IHEGIDNTLMILQQRLPDIQIIKEYGDLPKITCDASQINQVFLHLLTNSI
DALLERKNKCKSYHGQEISFSPTIWISSIVDDTKQAVIRVTDNGIGIDGN
IISKIFDPFFTTKPVGKGTGLGLSISYQIVEKHQGSLECLPSLTDGTTFI
VKLPISLK
>Ava_3976 Response Regulator Receiver Signal Transduction Histidine Kinase
MRATVPNQNYFSDRTPIKGIILAVDDNPNNLQVLSSFLDNSSFEVWAARS
GEKALQRLENDLLPDLILLDVMMPGMDGFETCQRLKSDQRFCDIPVVFMT
ALSETEDKVKGFQLGAVDYITKPFQHEEVLVRIEHQLKLRHLTASLIAKN
AELQKTQTQLIQTEKIASLGQMAAGIAHEVNNPINFIAGNLTFVQKYVQE
VVDLLYLYQQHFPNLPAEIENAINRTDLTYLLDDLSNVIKSMRVGTDRVQ
EIVSSLNKFSRHRETGKKLANLHEAIENTLLILGHRLKANSERPAIEIVK
KYGNLPLIECYPGEISQVFMNLIANAIDAIEETQKNQNYCEIAENPGVIH
ITTELIGEQVICKIADNGAGISEEIQSQIFNAFYTTKPIGKGTGLGLSIA
YQIVTVNHHGKISCHSQPGAGLEFIIELPIN
>Ava_1134 Cyclic nucleotide-binding domain (cNMP-BD) protein
MTEILLKELTKSDIDWMITTGNQQELAAGTILIQERGSTEFFHILLDGTF
SVTLSQPENNPLTRAFAAIEGEEISGREIGRLSRGEIVGESPLIGTRPPA
TTITSVEKSLVISIPIRELAAKLQQDVGFAARFYRAIAIIISNRIENTID
QLGRRNLAQSQPLRDVLFILGELHDSDIDWMMASGTPQKIPANTILIHEQ
GTVDALYILLDGKMSLSISLDERNPLVRAFAAIEGNEISGREIAKLSKGE
IIGETPFIDGSLPPTTVKAIEHSVVLSIPRQQLAAKLQQDIGFASRFYRV
IASLLDQRLQPMVSQLGYGRRVYSRGESLHEGLEYDDELDINTLDRMAIA
GKRFDWMLERLKVS
>Ava_3402 Response regulator receiver domain protein (CheY)
MNNQSLARGKVLIADDDEDSRMMLSFVLQEEGWEVYEACNGKEALEKVIE
EKPDLLILDNRMPELSGVEVYQYLQAEGIHIAVVLATAYGYLDELASSLG
VEHFIHKPYEIPALLKMVESAYAHSRN
>Ava_0620 conserved hypothetical protein
MNKWAILSGIEGNLAAYEAVMADIKRQGDEIQALYILGDLVGPRPEVEKV
VERVRNPRNGELEPLVCKGWWEEQCCILHGLGPTGEADDLLAQYGGETVK
LLWDSVSRQTVQWLRTLDFGFFELDCLLIHGTTVSIDEALTPDTSPIQML
DRLARMQASNLFCGRSGLAFQYHLQAGSVTTGITTLDNPKSPETMTISPR
QIIGVGNVGRTPGVATYTLYTPATNYVEFKTIRYGVGQGFQHNSVKAISS
>Ava_0278 Serine phosphatase
MPVPQFSSQPTDNNNSAATDVTPVVALKELVSRLHREQNKIQDLLSSLGF
ALRSFNNLNQFLELIPLMATRVTDADGSALFLYKPNGQVRLEQLHWQDSR
QRKNIRKALETASSQITLLPNTAPLANATGMLDDQMHRYLGPDVQIFGTA
ILVKHTERGWLYVLSRDPEYSWTETRQKLVRLVADQTAVAIENDELAVEL
RKKERLDQELEIGAEIQRRLLPRQCPHIPGVSLAARCRPANRVGGDYYDF
IPTNQSQIHPYTKLGQDSGRWGLVIGDVMGKGVPAGLIMTMMRGMLRGEV
LHGNSPAGILQNLNRVMYADLENSHRFITLFYSEYNPHKRILSYSNAAHN
PPLWWHAATKSVTRLDTLGMLIGLDANSQYEDGHAQLEPGDTVIYYTDGL
TDAAAASGDRFDEENFVTAFSTACRYCNGPEEIVDYLFDRVQQFIGADRQ
NNDDMTLVVLQIE
>Ava_1153 Serine/Threonine protein kinase
MQVIGTLTYKKIQQIGVGQGCNSQVFLIDEEQLGGLLVAKEVDKRRFHSS
QTYFQEAKIIFASQNPNVVPINYACETPNTITLVMPYFSKGSLADRIQQN
PLSLTEVIRMAQGVLNGLHHIHIKNYLHLDIKPSNIFFSNTDQPMIADFG
QSDSLDQNGIVHSPQMYFHTLPPESFPPNATATVESDIYLMGVTLYRAIN
GDQIFNSQKIPINSQLDFIILQDAIQRGKLPDQNYFLPHVTQSLRKVIRK
ALNVDPKKRYKSAIELADALGKIEIPLDWNTQISSNGDILWIASQGKGKP
YLGVELVKNLHDLWNVNVFTDNQGTRRKKLQYCRESLTFSDAETHLEKTF
ATLA
>Ava_3867 Serine/Threonine protein kinase with WD40 repeats
MTILNLLQNRYRLINLMSRGGFCQTYFAVDEGISPPVYCVVQKFSGNGKI
SDIFGQKAKYIKNLGQNPQLPTLLAYFQDQDNYYLVQEFIAGASLAQVVQ
EEGAFPETQIWQLLTNLLPILKWMSDRQLIHGNVKPANIIRRPTPTSTNL
VLVDFGHVQIVSRTDQVSDLQGVGSAEYAAPEQIKGKAVFASDLYSLGVT
CIHLLTMVSPFDLFDIPNDCWVWQQYLTTKISDRLSKILNKLIQKSVDQR
FQSADAVMQVMGIEGKILHYPPPLSPWQCLNTLTGDYCTNSLAISPDGNT
LASGGDDKIIRLWELNTQKLVASFSGHSQAVTSVTFSPQGEILATASDDK
TVKLWHLPTSREVFTLNGHTKPVKSVSFSPNGQILASGSWDKQVKLWDVT
TGKEISALKAHQLQVSAVAFSPQEEILASASFDRTIRLWQITQNHPRYTL
LKTLSGHTRAVLAIAFSPDGKILATGSDDNTIKLWDINTGQLIDTLLVHS
WSVVAVTFTADNKTLISASWDKTIKLWKVSTTEEIVTLASHLDSVCAIAV
NPVAQMIASSSRDKTIKLWQLVIQQN
>Ava_4863 Serine/Threonine protein kinase
MVNPKTEPDVYIGKFLNNRYLIIDLIGKGGMGRVYLAEDAAKGGKKVALK
ILMLNLVNQHISQRFAREIFIGAQLGRKSKNIVRVLSYGVTDEKTPFYVM
EYLQGKNLKQILKLKPLTIEKFLDICYQICVGLKCAHQGIILKGEIYPIV
HRDIKPENIFITENNKQNENVKILDFGIAKFLTERSGMTLTDSFIGSLPY
CSPEHMEGRKLLDVRSDIYSLGVLMFEMLTAKHPFQTQSNSFGNWYQAHR
FQAPPTLVEVNDQVKIPEELQDLVMCCLAKEVGDRPQNIEEIIQVLELVK
QQNTSSNSISNDIWETLPTVQLVPVTSITEKECLQKTWPKNKPVDLIGFP
HLLHTTQGLIPTFWAMLPKQEIAQFLSKNNSIKFINKMNVYPMILWVTLL
YDVQLSLIRWLSYFIDLQENRGQKIVKALAETGYYHLLFFAIEEPTNCAQ
VVTLILTAQQRQQLTDWLTFKQNIKSNELVPAEQARKILKTEYEKIKLEI
LESLAVNKPQEQMEIKSWLTKLIDKVLQIFKYQS
>Ava_3066 Transcriptional Regulator, Crp/Fnr family
MEDRYSLQSPANPWMISAPFFQGLPETAVELALNHLVTRTHPANQVILLE
NDWGGSVYFIVEGWVKIRTYNLEGKEVTLNILGTGELFGEMAALDEVPRS
TDVITLTTTMIGSMPSQDFVKLLHTEPLAGVRLSQLMARRLRQVNRRLRL
RESDSQSRVADTLLFLAEGQGKRGQTGTELPNLPHRELSSLSGLARETVT
RVLTRLEKKGLIKRDQDTICIPDLSALEKMLI
>Ava_1564 Multi-sensor Hybrid Histidine Kinase
MKAQLPDNEVQRIAALLEYKILDTQSEAAFDDITRLASYICGTPIALISL
IDQNRQWFKSKVGLERRETPRDEAFCTYTILESDVFIVPDATTDERFATN
PLVISDPKIRFYAGVPLTNPEGYSLGTLCVIDYIPRNLSPEQIEALQILG
RQVIKQLELRRNLANLVLVNNQHKQAQKIRHPFFKKIAGGFGLASVILVL
LGLASYQSEIELIHSSNQVQITQESINNLEKLLSQIKDAETGQRGYILTG
KDLYLQPYQTALTNIDQKFAELKNTTVDQVQQQRLVILKPLITAKITELK
QTIKLRQNQGFQTALQVIQSDKGQTLMDDIRKVMREMETEEKVRLQQQLQ
AVKASGQKVIVILAIAIVSGLIILAVVYYLIYCEVIARQSMENILNEERN
FISAVLDTVSALVIVLDSQGRIVRFNQACEVITGYSFDEVRGRHFWNLFL
LPEDVESSKASFAKFPTDSRVSGIQESENYWVTKDGSRRLIAWSRTILQN
HEGSVEYIIGTGIDITERKRADKHLTIQYAITRVLAESTTITEATPQILQ
AICETLKWDVCEIWMVNQQGNFLSFFDLWDQTSLEMQEFKTQSQPITFAS
GIGLPGQIWASGQPIWLTDIADDASFLRNQLAAQVGLRGAFGFPIRSGQK
ILGVITCFSHQVQPHDPDLAKIMDSIGEQVGQFIHRKQAEEELQRQNLRS
QLFTEITLKIRQSLQIEEILQITVKEVQKILQTDRVLIYQLLPDGSGSLI
IEAVVAGWAAIKGQNITDFYLQTEYQQQYCLQQYRLRHLEAIANLDLAEI
QQSHLELLRKFGVKANLVIPILVKDELCGLLIVHQCANSRQWTSFETHLL
RQIADQVGIAVAQAQLLEVETRQRQELEVARSQAELASHAKSAFLANMSH
EIRTPMNAVLGMTGLMLETLLNQEQRDFMETIRISGDALLTLINEILDLS
KLEAGEMALENLNFNLSTCVEEVLDLLAPQAHSKGLEIAALIYRHVPIQL
QGDASRLRQILMNLIGNAIKFTSFGEVVMRVELRSETPTTAIIHFAVTDS
GLGITLEDQHKLFTPFTQVDASTTRKYGGTGLGLAICKQLVTLMGGEIGV
ESQLGKGSKFWFEIPFAKQLQPVSFVEDCGLLNNRRLLVVDDHATNRKII
YHQVSRWGMQVDQADRAVAALGMIVEACQQNKPYDVILIDMQMPEMDGMA
LGKQIKANSAIPPTPLIMLTSTNQRDEVQQAIKIGFAAYLVKPVKSSRLL
DTIMSVLKTPSQLEAEKLEVKSQELEKNNLDHSRNRNFTATQAQNSVSTK
TRILLAEDNLVNQKVALKQLQSLGYTADVAANGKEVLQLLKQIPYDLILM
DCQMPILDGLETTKEIHRWAESSFASGRRPVIIAMTANAMKEDKQMCLDV
GMDDYLSKPVMKEQLATALEYWCQLILNARQAVEFDIHSLPIDWEHLHQL
SENDTEFELHLLQIFVEDVRARLELAKEAIANTDFQKMAQQVHQLKGAST
NLGATAMYLAAERLEQLANNQERRGSMELITEIEESVNQIQAFLTRSQVV
>Ava_2440 Two component Transcriptional regulator, Winged helix family
MNRILIAEDEPRIAAFIEKGLRSQGFTTAVATDAYSATNMALSSGFDLMI
LDLGLPGKDGLDVLEELRGQGENVPVIILTARDDIQDKVAGFEAGADDYL
TKPFRFEELLVRVKARLRQSGGSQVMEEMVIKSGHIVLDLRSRKVKIGQD
TIELPAREFTLAETFFRHPGQVLSREQLLDRVWGYDYDPGSNIVDVYVGY
LRKKLGNDLIETVRGMGYRLRT
>Ava_3166 Response regulator receiver domain protein (CheY)
MFSCESSTLKVLVVDDHELTRLTLQLAFSSQENIQVVGLASNGQEAIEMV
RDSHPDVIVLDLQMPVMDGWSASCHIKAISPNTQILAYSSVEDIRFLDTK
TTSNFDDVCKKDVPTKELIALVRELGRRGANSSISQ
>Ava_2990 Serine/Threonine protein kinase
MPWIAGQQLQGGKYVIEKVLGQGGFGITYKALQVELNRPVVIKIPNEFLS
HDPEYEKYVERFIKEGRILARLSQEPHPHIVGVIDLFQEGNTHCLVMEFV
EGENLFEAIKHRGALPESEIVRCISQIGEALVKVHQAGLVHRDAHPGNIM
LRKNGKAVLIDFGIAKELLPQTLSSTGNIGNRGFAPYEQMTRGSREPTVD
VYCLAATLYYAVTGQPPTNSLARKLENVPLKPPKQITPNISNQLNKAILK
GMALEAQDRPQSMQAWLAILEAPKPTPPYSVVPVHKKEAVSPKPKIKLQA
SPRKAVTKSHSIIPWGCLIGILFSSLFIGYLFAMSNAPFWAWAVTVAGTL
TWAVAVSGVVVGGAVAVAVVGAATVALVGAATVAGAGIWAWFWALAVAAF
WGGAGEKLQNYFSQFHTFLILVTTSFFGLGLGLLVHRVFNVL
>Ava_0538 Response regulator receiver domain protein (CheY)
MSDRPLKLLLVDQDPIFRLGLRVALEAMPNIEVVSEAPTDTAALQILAEL
AQINPNQVDLVILELGNSRSVDSQQQGLQLCQQLKATYPTLPTLLLSAIP
DAGLIMAARAAGVRGYCPKGTPISQLVTVIEAVAAGNSYWLTETVNPEIT
PSIAAVAPRLPLAKWRQNLHISSVNYIDHALQEVTAQLQIPGLPILDRAV
LAGKRRELLASRWLLNQVLILPQEKQQLPLTSSVAKSLPIVPPAIPTISA
SNSQQTSPSPPLLSPRALQTNLFASCINKLQFPLNNVSDSVLEIDIFRED
KKRELLYLILQKLAQQLDALRNAQITVNQLGELQPIILHDLWQAVITEFF
GKFSRVQVGKRNLEIVTVLLQNPEVVQTAILNKIPLGLELFSYLLLQTDL
RIDHHTYPAGSSEANSHAEILLENLIIQVANAVVQPLLNYLADIEEIKQN
FYVKSLMSTRELERFRNDLSWKYRLNNYVTEAKAIFESRYELLVFAPRGI
AQISIYAPRNDELAQLSGVPLVVTLGLEFRDAIAPRLQSLLSVLGSGIVF
VLTQIIGRGLGLIGRGILQGIGSVSFDKNFKRDSERPK
>Ava_4305 Periplasmic Sensor Signal Transduction Histidine Kinase
MKISTKLLTGSTISVGLVVAILIGNTVVVQQIRQNVREKSYQTTQTIKAV
LETNNTLKSEIIVLKDIVLFKTKSTSTEILHAEFLDSLNQVEQLMPNSPE
IALIRRRHQLLDNMAVQLTQRSASPTYLEDSQQYFRAINSFNQDIQLFLE
QIIQRAYQERILLEQDLQNLYQVQRIISIVVVAIILMLLIGKFILIWQPT
IKSIQNLQLGTAEIAAGNFDYRLNIHTGDEIEDLAQSFNDMAGKLSQSRE
TLMKNTELTNMNQRLELEIAERKQAELELQKALQELQQTQAQLIQTEKMS
SLGQLVAGVAHEINNPVSFIYGNIIHANEYTEKLLELIHLYQQELSNPSA
VIQEKIAEIDLEFLQEDLPKILSSMKMGSQRIQQIVLSLRNFSRLDEAEM
KEVDIHEGIESTLLILQNRFKAKSQSYNIKIIREYGQLPLVECHAGQLNQ
VFMNIINNAVDALEGSVVSGQWSIVNGKTTNNERLTTNGPQITIRTEINH
NNRVVIRIADNGPGITQQVMPKLFDPFFTTKPVGQGTGLGLSISYQIVVE
KHSGVLRCESEIGKGTEFWIEIPLRQVQPEKLEHGFSAMLTREV
>Ava_2923 Response regulator receiver domain protein (CheY)
MKTLPITRYRFFQKIQPLSLLKKITGKTITGCLQVFSTSGTWSIYVEEGK
LIYACYSERMFEPLYRHLGNLSPQIATLPKEINEQLRAIFETGIENQAIP
NPDYLAICWLVNQKYISSSQAAVLIEQLALEVVESFLMLEEGSYEFIPES
FLDDLPKFCYLNVRLLVEQCQQRGRVPEAFRREASSQEISSSTESNQIPV
NSKRSTKFTPPPHTQPKPKPEPSLPQINTNKSIEYSKRYVSQSNTINHGY
SQISPTSADKKIYTIFCIDDDPTVLNKIKNFLDDQIFAVIGVTDSLKALM
EILCTKPDIILINVDMPDLDGYELCSLLRKHSYFKNTPVIMVTAKAGLVN
RARAKIVRASGHLTKPFNQGDLLKVIFKHIT
>Ava_B0019 conserved hypothetical protein
MLNLKKASPGKKEPLQLLSYNKYVTTRVGIISLAGFSMAALSLLLQFLNY
GAISVLNRKQLALVQLSSGDTIAARAVDPKERSDEVIKKFISDTFIKMFN
WDGLVQTFNEKGEPITKQDTGIEVGRIDNKSNSRVVAKAYDTAFALSENG
GFRAAFLKKLASITPNGVFNGESQVSLIPRFISQPRQIREGKWEIDFIGT
LVTFDRADNSGRGIAFNKTITVSSIDNPEYIPANTSELAKKIYAARGAGV
EITEIVDLDLGKRK
>Ava_0144 Cyclic nucleotide-binding domain (cNMP-BD) protein
MQTEVFSDIFPLLSTATPQTLEWLLNIAIDHEYPTGRAVLMEDAWGNAVY
FVVSGWVKVRRTCGDDSVALAILGRGDFFGEMAILDESPRSTDVIALSPV
KLLSISRERFIQILFKDPQLHHRMLQLMVRRLRQINQRLQIRSSPPAVKL
AHTLVSLGESYGQESEQGREIFNIPFKDLAEVTEIGVEETSKIMDKLHDK
GWIKIDSANNIIYLINFKQLLNLAGKV
>Ava_0065 Response regulator receiver domain protein (CheY)
MTKILVIEDQEEIRSIIVEMLTAENFYVMDAENGQVGITLLQTEIPDLII
CDIAMPKIDGYEVVTWSRENPETEAIPFIFLTAKASQNDIRQGIELGADD
YLVKPFTRAELLGAITARLEKQEIINRQTQQRLHKSYIYLTSTIRNEVNN
PLNYITSISEKLINDYEFMNREEILKKIKEIYNLSKNFQDGNLNKL
>Ava_2884 conserved hypothetical protein
MKKTILFTLGLLGLLIAPATAQLGKVWTEFQFYSTDLQNYLKYNLSETLK
PLESSSQNALNGATGDLNIPNPIAAGEQVRKDIIFFNSIPDKFESNQAIR
SNSVTNEINRYLTRSSVEGTLGKNGQRRMKAKLEDTEASVTKIEEYSALT
DQIQSGLASILQAAVNTAAAAANPALNAAQSQADLQVQSIKIQTEQSKII
SENLYQTVLANQSLQYSNLNLANISQQMEEANRARRVDTSTEAARLLRTT
SQIDLFGRKNEN
>Ava_0314 Signal Transduction Histidine Kinase (STHK) with CheB and CheR activity
MNSSPAKKSQSNTPDEEQQGNENELFPIVGMGASAGGLEAFTELLNNLPS
DTGMGFVLIQHLVPDQKSLLSEILSQTTQMPVVEVQNGMVVAPNHVYVIP
PNTMMTISQGTLYLSPRKKTRGQVMSIDTFFFSLAEDRGNKAIAVVLSGG
DGDGTRGLEAIKAAGGITFAECQESARVSSMPNTAVASGSVDFILTPQAI
AQELANISRHPYIKPTTPEKSTEVIPETGDALHTIFSLLKAATGVDFNYY
KQTTLKRRIFRRMILYKLERLEDYVRYLQENLAEVKALYQDVLITVTNFF
RDPEVFEALKTTVFPQIISREQTPDKPIRVWVAGCSTGEEAYSIAICLLE
YLSNQSINTTIQIFATDINEVAIEKARIGIYKPSQVLDVSPARLQRFFVP
VEGGYQISKPVRELCVFARQNLISEPPFSRLDLISCRNVLIYLGATVQKK
LIPMFHYGLKSTGFLLLGTSETVGEFSDLFALVDRKHKIYSRKMAPARLG
MDLLASHYPTEPAKPQPPVNEDGWNDLQMQKEADRIVLSQYAPVGVIIDN
DLEIVQFRGQTSAYLQSPPGRPSFNLLKMAKAELRLELRTAIHQAKKRGI
AVKKEGLLIKDNEQVKLIKFDVVPFKAPGRAERYFLVMFAEMPTAATSML
GVAGDETRQQKQTNNAQEINQLKQELASTKEYLQSIIEEQQATNQDLRAA
NEEILSSNEELQSTNEELETAKEEIQATNEELNTINDELQRRNIESTQVS
NDLQNLLSSINIPILMLGGDLRIRRFTPTAERIYNLIPTDIGRPLSDINH
NLNISDLEQQIQEVIGTLTFKVQEVQDNEGHWYDLRIRPYRTMDNKIDGA
VVVLVDIDALKRSAEQLRASRDYAEAIVDTMRESLVVLDLNLRVVRANRS
FYETFQIQPTETEQRLIFDIGNGRWNIPQLRSLLEEIPPNITPFQDIEVG
HNFEQLGYKTLRLNARKMPQIDDTQLILLLIEDITQQKQLEAERTQLLAQ
EHSAREAAETANRAKDEFLSILSHELRNPLNTILGWASLLSTHQLEADTV
NQGLEAIERSAQAQAHLISDLLDVSRISSGRLRMDAQPIELIPIIEAAIA
VVRLAAEAKNIHIETQLDPTQKTIVGDPIRLQQVIWNLLSNAIKFTPVRG
RIDITLEYTDFHAQIQISDTGQGISPDFLPFIFERFRQADGSRTRSNTGL
GLGLSIVRHLVELHGGTVAAQSPGEGLGATFTIRLPLQTTEGGTSVLNTS
DSLASTNKTELSTENIASLAGLRVLVVDDEPDIRLLFKLVLEEYGVEVAT
VGSASAALSTLTGNPNGYDILLSDIGLPGEDGYALIRNVRALSPELGGQI
PAAALTAYAGYAEYAQALAAGFQMHLAKPVEPYQLVSLVASLAVGVRGV
>Ava_3204 possible Sensor with GAF domain
MQIHSHAEFDPSSNQPTEQGLQRVLQRLVQTMQRDALVRQTTNRLRESLQ
IDRVVLYYFYWQWHGQVTFEALSSEEFSILGSTGADECFNDEYAELYLAG
RTKAIADIESASITPCHRDFLRTLQVRANLVVPVLVPKGLWGLLVAHHCQ
GTRFWTESDIELMQTGAKTLATSPYILES
>Ava_3452 Periplasmic Sensor Signal Transduction Histidine Kinase
MKLPSFRLRIALLSAALAGTTLVGFSAVSWLQIYDAKLSRLDAELLNQLM
RAAPNLLPPREPPTFFTRENFRPPMPEPWQRYEELLSSAFGGNAKTPIVL
LVLDAEGNQLYESPQTSPDSDLRRLLLQNLQLAPQPQPPRPLPNLPLRPP
RPPQFVTQKTTSGSWRIGATKFPRSQVAIAVSLQTVNQEMAAIRNIYLVS
IPIALLLVTSGAWLVSGSALRPIRQLTAVIQQVSAKGLDQRIPIGTTDVE
FVELIQVFNQMLERLESSFTQASRFSADAAHELKTPLTILQGELERTLQQ
VEPGSEVQQRLSNLLDEVRRLSGIMRKLLLLSLADAGQMSLYLVEVDMSE
LLMEMVEDVELLAPHLSVHIEIPEKLRVKGDRDLLIQVLQNLLSNAIKYN
LPQGWIKIHAHQTPTTIHITISNSSPDIPPSDRDRLFERFYRGDPARTRK
VEGIGLGLSLSREIARAHRGNLTLDAENSGQTRLTLTLLR
>Ava_4518 Two Component Transcriptional Regulator, LuxR family
MDYGLLTIDKKMSPNTGYFLNLPSNAPRLRILIVEDDPMMQLGLEQSLMA
HPQLEIVGQAEDGYLGVQAALALKPDLVVMDIGLPRLDGIATTQQIKAAL
PETHVVMLTSHKTETEIIAALSSGADAYCIKGASIERLLNAIAAAVDGAA
YLDPQIARQVIDHLKPPSAKGNTANLSGRELEVLKLMVEGLSNPEIAEKL
YLSPNTVKTHVRGIMNKLAVDDRVQAAVVALRSGLV
>Ava_C0162 Response regulator receiver domain protein
MSSYTNRCILVIDDEPDLCSIVKFTLERLKSWKILTAESAQAGLMQAETQ
QPDVILLDLSLCGQYRLTMLQSLKTNPTTQSIPVILFTATDPSDDSLGFD
PSEFAGVILKPFNVLQLGEQIIEQLGW
>Ava_C0037 conserved hypothetical protein
MKPKFKFTKKGVIIGSIIGLVTLLGTAPSYAFSIDDFFKVLGKFNNYFEE
TKKELTSGTNKWGGMKGEAKTAIQTGSMDMPDPVNSAEKLKEQLKSKGNW
NESNTVEAAVSAANELERETTRATIASVLGEVGQERTKNEIEATQQTVAE
AKELAESAQPMDASQNILKVIAAQNSQIVSMLGQSRIDGLQTRHDAQQTN
LMLSQLAEQGASDRRRQNLMMDGISAQYIEISGFSSLKTTAGE
>Ava_4781 MCP methyltransferase, CheR-type
MILPKPSLEDIEIKLLLEGVYQYYGHDFRNYAVSSLKRRIHSFMRLEGVD
NISALQQQLLHDRACLERFLLSLTVNVTSMFRDPSFYLAFRNQVVPILRT
YPFIRIWHAGCSSGEEVYSMAILLQEENLYHRCRIYATDTNEKVLQNAKS
GIFSLKMMQEYTQLYLKAGGKRSFSEYYTAAYDHAIFRASLRENIIFAQH
NLATDSSFNEFNVIFCRNVLIYFNQILQKRVHTLFYNSLCSFGILGLGKQ
ESIRFTPYEQYYEEIAKGEKLYRRLN
>Ava_1990 Metallophosphoesterase
MTSQKYQSKTLKIAVVGDIHDQWEVEDGMALKHLGVDLVLFVGDFGNESV
EVVRAIASLNIPKAAVMGNHDAWYTATEWGRKKCPYDRTKEDWVQEQLDL
LGSAHVGYGKLDFPEWNLTVVGGRPFSWGGHEWRFADICKDRYGVTTLEE
SAQRIFASVKSAACETIIFLGHNGPSGLGDRPEDPCGKDWHPIGGDFGDP
DLAEAISLTMTTGKQIALVTFGHMHHSLRHTKKELRKPIFKSPEGIVYLN
AASVPRIVEGESGKLRNFSLVSLEAGEVTQASLIWVGEDFQVAKEEIFYE
RSTSVVPSV
>Ava_3722 Anti-Sigma-factor antagonist (STAS) domain protein
MLLYNIGKFSTSFYSKLVKNTMNQQVQVIKLSGIINTANSQELREEITHL
LNSGTKIVLVDCQDVIFMDSSALGALVLAFKTLRAAGTKLFLCSINEQVR
ILFELTGMDKVFEIFNNQDEFNQIILANS
>Ava_3616 Response Regulator Receiver Signal Transduction Histidine Kinase
MSLPTAQSGKILVVDDSPDNVFLIKTILEEEGYTVSTAENGISALAELQA
SPCDLVLLDLMMPGMDGYEVTRRVRGEMKLQQYIPILLITAHDAPNVAHG
LDLGADDFIRKPVTVDELLARVRSLLRLKHSMDERDEIARQREDFVSRLT
HDLRTPLVAADRMLALFQQGALGNLSPQMQEVITIMARSNINLLSMVNTL
LEVYRFEAGRKTLAFQPVNLSQLLNEVIAELTPLAQEKNLAINSDFGDTS
TPNKLGDGIPPTVGDRLELHRLFTNLIGNAIKFTASGSVTIRLKGIILNA
KQDFSDPSLLSSNIDYVQVEIADTGAGIPLEEHATLFERFRQGSHKISGS
GLGLYLSRRIVEAHHGKIVVNSELGKGSVFVVSLPIQIVGKAD
>Ava_3310 Serine/Threonine protein kinase
MEQLLDNRYRVIKTLGSGGFGETFLAEDSQMPSNRRCVVKQLRPIHNNPQ
IYQLVQERFQREAAILEDLGSYSGQIPTLYAYFQSNTQFYVVQEWVEGDT
LTAKLKQQGVLSESAVRDILINLLPVLEYVHSKRIIHRDIKPDNIILRHR
DGKPVLIDFGAVRESMGTVVNSQGNPTSSIVIGTPGYMPSEQAAGRPVYS
SDLYSLGLTAIYLLTGKQPQELETDPHSGEIIWHKYALNISPTLAAVIDR
AIAYHPRERFITAREMLDALQLGVVSPPTVPYQQPQSSPTIPYQQPPVVT
TPPFATQTNTVAVSPGTTPTPQPINHNNSNRGILMGSLIAGGLIGASVVI
GFALTRPNQPVTQTTSLPSETTISNNATPTVEPSPTATPETPINQNVTQN
TTPQASVRFPTNSRPFTTPIDSQPRNNTEPNTSVPQETTPPEPQITTPPE
QTDRPSPEEAVQNYYETINEGEYSTAWNLLAPSFQNNRRLHPRGYDSYLD
WWGGQVESVDVQQVNLVEANADTATVNAQLRYFMKSGRQSSSSVRFSLVW
DADNTRWVVSGAR
>Ava_4096 Two Component Transcriptional Regulator, LuxR family
MNKIRVVLIEDHDLTRIGLRATLQKLDGIEVIGDARDAASGLKLLKSTQP
DIAIVDVGLPDMSGIELTQHFFNSMDTQQTPQTKILIMTMQDSEDTVLAA
FAAGADSYCMKDASTDKLVEALHLTVNGNSWIDPVIARIVLQQTQKATTA
ANARPDTVAINGLSPEYSHIVETYPLTRRELDVLKLIVDGCSNAVIAEKL
YVSVGTVKTHVRNILNKLCVSDRTQIAVRALRAGLVA
>Ava_0590 BolA-like protein
MITPQQVEAMIKAELPDAQVQVQDLTGGGDHYQVTVVSSQFAGKRLVQQH
QLVYGALRQAMSTEAIHALALKTYTPETSQ
>Ava_0058 Response regulator receiver domain protein (CheY)
MSTTPINNYRLNHKLHPLSLLAQLTSRHATGCLRVFTDTTSWTINLEAGK
LTYASYSDKLFERLDNQLRRLSQKIPTLNSATRVQMRLMFEPKSEGQSIL
YVDYQAICWLVDQNHINPKQAAILIEELAKEVIETFLVIKEGSYEFFPDI
TWEEMPKFCYLDLRVLVEYCQKQLRQRQPKPPSVNTGGGSQVLPSTRPAS
SPSSPQNHPENSENSQPINPPSLVRKTLYTIACIDDSQTVLNSIRSFLDE
NVFTVVTINDPVKALMQVLRSKPDLILLDVTMPNLDGYELCSLLRRHSAF
KNTPIIMVTGRTGFVDRAKAKMVRSSGYLTKPFDQSELLKMVFKHIT
>Ava_0091 Adenylate/Guanylate Cyclase
MTLPNPGSVLASLTELTQVNRTHALLRRVKDLSVNEFVCLLDFITAEFQQ
FLRAIELINNEALENMLEKVLEAITLKIGQILQAEHTAIFLVDYDKCQLW
SKVPQDNGQKFLEIRTPITVGIPGHVASTGQYLNISETSTHPLFSPELEK
QMGYKINNILCMPVLSSKDQIVAVVQLANKTGNIPFNRDDEESFRDFAAS
IGIILETCQSFYVAARNQRGVTALLRATQTLGQSLDLEATLQIVMEQARI
LMQADRSTLFLYRKEMGELWTKVAVAADTTQLIEIRIPSNRGIAGYVAST
GDALNIADAYKDPRFDPTTDRKTGYLTRNILCLPVFNSANELIGVTQLIN
KQQGSFTASDEEFMRAFNIQAGVALENARLFENVLLEKQYQKDILQSLSD
AVISTDMAGRIVTINDAALELLGCPLADAHHKSNKLLWEQNLIGRVVWEI
VPIENLQMRLEDSLKSGAKHYVPEQSLTVGIYQLQMSESRVLHETQDYSI
LTVRDRTNPDIFLPWNLPQTPQSQFITPEKLQILERSINLTVNPLTNPEG
GVRGGLVVLEDISQEKRLKTTMYRYLTPHVAEQVMALGEDALMVGERKEV
TVLFSDIRGYTTLTENLGAAEVVSLLNQYFETMVEAVFNYEGTLDKFIGD
ALMAVFGAPLPLTENHAWQAVQSALDMRQRLKEFNQRRIIQAQPQIKIGI
GISSGEVVSGNIGSHKRMDYTVIGDGVNLSSRLEAVTKEYGCDIILSEFT
YQLCSDRIWVRQLDKIRVKGKHQAVNIYELISDRSTPLDDNTQEFLFHYH
NGRTAYLSRDFTQAIACFNLAKHIRPTDQAVNIHLERAYNYQHTPPPPQW
DGVWTIFTK
>Ava_0789 TspO and MBR related proteins
MIKSWMVIGGVAILVALAANVMTPSDRKWFNRLQRPRWLTFEAAIPVIWT
VIFICGAWSAYIVWEKNPGTNTTWIIMGLYLLLEIVTIAYTPVMSKLRSL
RVGTIVGGTGLVVSIILTLVVLNISGWAALLLVPYLLWSPIGTYTTWQMA
HLNPQDA
>Ava_0791 Response regulator receiver domain protein (CheY)
MPHVLLVDDEVALCESLAYTLQKEGYTVTTVADGQSAIKQFHKQVPDVIL
LDLMLPEVSGMEVCWRIRAFSDVPIVMLTAKDQDIDKIWGLEAGADDYVT
KPFNTRELLARIKAVLRRRAGEQPA
>Ava_4783 PAS/PAC Sensor Hybrid Histidine Kinase
MQPEPKVNILLVDDKVENLLALEAILERLGANLVRATSGEEALRCLLHQD
FAVILLDVQMPGMDGFETATLIRNRGRSRQTPIIFLTAFSTSDQMLFKGY
ALGAVDYLLKPIDANILTSKVTVFVELFKKTQAIQRQAAQLAAINAELRQ
SEERFRSLSTCSPIGIFETDTAGCCKYTNPRYQAICGLDATESLDKRWLE
SVHPEDQERAIASWSTYIDQGGDYSDEFRFQTVDGSLRWVQVRSSPMLSG
NGELLGHVGTLEDITARKQSEEIRAQVIREQTARQEAEAANRMKDEFLAV
LSHELRTPLTSMLGWSKILRAKKLDEKATARALEAIERNANSQVQLIEDI
LDVSRIIRGQLRLNLSPVNLTTVVEAALEAVRPLADTKSMTINTALDYTL
SPVSGDSARLQQIVWNLLTNAIKFTPKEGKVEIRLEGISGGLSDDLTHAQ
IQVIDTGIGIEREFLPKVFERFRQADSTTTRSHNGLGLGLAIVRHLVELH
KGTILAESPGVGKGATFTVRFPLIQENREPRPAPTENFSGDGANSSPLAG
LKVLIVDDETDTRNFLGFLFEEYGAISSTSASVETALAVIDQLKPDILIS
DIGMAEQDGYTLIRKLRSLPPEQGGEIPAIALTAYSREEDRQQIIEAGFQ
YHLCKPIDPNQLISVVASIFRLSPALSKLG
>Ava_2944 Multi-sensor Signal Transduction Histidine Kinase
MQVVVVKDITASQANQEGMRITESVRRKQNQTLVQLARSKTFQQGPLNAV
LQEITEAAAQTLLVARVSVWLYNQDGSAIECIDLYDVSQQIHSSGQSLLK
ESYPIYFQTLEEERSIAVYDAINDKRTQELSATYLSVAGVVSLLDAPIWV
GGRLVGVVFHEHCGELRQWTVDEENFAGSIADFVSLAMETRERNIAQEAL
RKSEAQFRAIFELSSIGIGLVDMKAQIVDANPALCQMLGYQREELCGKRF
TDYISQQRGDVERYKQLMTEICIDAQQHHEKPHLEIERAFLHRDGRLVWT
RLSVSVIPGSYGEPEYFLAIIDDITDRKQTEMKLRASQAAAEAGSRAKSE
FLATMSHELRTPLNAIMGLSQLLQQEIVGSLNEKQQEYISCIYSSGEHLL
ALINDILDLSKVEAGKEELFLIPLLVIDVCNDVLLTVRDRAISKGLKLTQ
EIDPEASICIADDRRIKQMLLNLLTNAIKFTSVGEVSLTVKRVPEGINFI
ISDTGIGIDSNQFPLLFEPFKQLDSRLNRQYEGTGLGLALTRKLARLHGG
DVTVTSTVGVGSQFTLFLPDQEI
>Ava_3004 Signal Transduction Histidine Kinase
MQLIINYSSNKAIMLFTDSESLRLEALYQYCILDTPPEEVFDDLVNIAAD
SCNTPIALISILDSQREWFKSKVGISELEIPRDICLGIHTIGQNDILIIP
DTWQDERFVENPLVRQKPSAFRFYGGVPLINSEGFALGCLAVIDFTPRNL
SLKEQQILQRLARQIIRQLELHKKRINHESSFNAHLLFTNNPRPMWICEM
QSLQILDVNQAAITQYGYSKTEFLQMQFAQVFVPEFISDLIRDIEQEYSQ
LPFLMECQHRLRGGQVIDVELAINYIEYSGYQACLVDTINITEHIQIERN
LQKSEARVRTILEAIPVPLVISRVDDGLILYTNSEFLQTFQLSGNDLINH
YAADLYENSEDRQQILEALSQHGSLQNYDIQFKKSDGTSFWAIASIQYLN
FNNEYAILTVLYDITERKNIEAKLQEQNALLQSIFAGIPLMIALISPEGQ
VQWINQELERLLGWSLRDYQTLDIFAELYPQPEYRQSVIKFMQSGECIWG
DFRTQTRYGQVLDTSWINIKLADGRIIGIGQEITERKQTERALKGQIERE
QLMRAVAQRIRQSLNLQNILNATVKEIKDLLGVDRVVVYQFAPDMSGKIV
AESVKPGWKIALGADIQDNCFQSGAGADYCQGHKRAIANIYTAGLTDCHL
HLLEQFQVKANLVVPILLEVSEGNTVPQLWGLLIAHQCSTPRDWEAHELD
LLDQLSVPIAIAIQQSSILQQAQNELAERQKVEVRLRSALAEKEVLLKEV
HHRVKNNLQIVSGLLLLHSQTLKDPELIRTLQESQNRIESISMIHKNLYT
SPNIGQLDVVDYVNNLATSILISYQLEPGRISLETHIHPVDLNLDQAIAC
GLIINELISNSLKHAFPQNTTGAIKIDLQKVDDKIEMTIQDNGIGLPDNL
DWRYTDSLGLSLVHDLVTEQLEGTVSIERQPGTTFKIQFSH
>Ava_4862 Serine/Threonine protein kinase
MNQSAFTSPHNTGLLANRYQLQKLIGIGGMGEVFLATDVLLGGAPVAIKF
LTQTVSDPKIQKDFAREALMSAALSQKSLHIVRAYDYGVSDTGKPFYVME
YLNGKSLKDLIPLPLNQFVHLTRQICLGLQCAHQGIQIEGKVYPLVHRDI
KPANILVIPDPILGQLVKILDFGIAKFLNHTVTLSTNRGFHGTLPYCSPE
QLDGEKLDGRSDIYSLGVIMFEMLTGAKPWQPETDLFGAWYKAHNFEKPR
TIADVKPQLKIPQQLNDLIMACLEKKASDRPQNVGEILRTIDGLEQSDCA
GLPTNISPPSYPKLISASDVIKALEQQCKELTWPQDKPKKEIVFPLPLNT
HQKNLSTLWLMLPKKEIQQRANSKIYNRFIFVTSPHPMLLWVTLLYNQEQ
EPKWLPCYLDMQHPLNRTLVLSLADNETYPLICFTLEPPHRCIQVLSSNI
ETSQRQKLKIWVEQSQKLPPTSQPLASKNLLRQQYKQIQAHMLQHLSSTR
RLEKLAKG
>Ava_4698 Adenylate/Guanylate Cyclase
MIWAKLKPLFWQWRGVIFAVPNMTILVIGLRLTGLLQLLELAALDQFFLL
RSPEPPDTRIVIVEINEADVRKQTQWPMSDAAMATVLDTIKQQQPRAIGL
DIYRDLPVNPGHEILVKLFASTPNLIGVQKLSDTRDSSAVNASPILKENN
QVGSNDLPLDGDGKIRRGLLYVDVNEDEVLESFALKLALLYLKPEKITEK
PAANNPDYLQLNRGVFPIFEANDGGYIRADARSYQILLNYRGRIQQFTTV
TLTQVQQKQIPPDLMRGKVVLIGATAESLKDIFYTPYSSNLFTPPERMAG
VTIHANLVSQILSAALDSRPQIQTLPETGEWLLILAWSIIGASLCWQQRS
SKRQKIVVAVGVPLMSGAVIAGSFLAFVAGWWIPVVPSLLAFGGSAIAVT
LYIAQSAGEMRKNLGRYLTDEVLANILETPSGLKLGGERRKVTLLFSDLR
GFSAMSEQLSPEQVVQILNLYLGVMTDVINQYKGTINEFIGDGIFIMFGA
PICRPDDSQRAIACAIAMQQAMQQVNAQTRQMNLPQLEMGIGINTGEVVA
GNIGSQKRAQYTVIGSHVNLAARIETYTVGGQILISANTRQDAKTDLQIA
GQMQIEPKGIKEPITIYEISGIGGAYNLSLPEDKDVMVKLKSPVPVEYQV
LQGKQAVGEVFRGELVSVSEKKALLHSPHPVEKLANLKLKLLHEPELATA
DIYAKVMKQSDADLFIIRFTNIPPQAIASLNSLHQ
>Ava_3362 Periplasmic Sensor Signal Transduction Histidine Kinase
MQTQQPIPVDSSSDSKEVSLEEPSTSTDELPTIEFPSRGKLKASSWRIHQ
KIGYGYFVAIGIGFFGSLTGLVIANYYRGKEIREFNQAQEQRQLLTDYKN
AVIGAQLHSSNIVAFLEDPQRLPMKKADFLRDVKKAEAGEQKIAKFIEGR
PKDLAATSVNLKALLQDYAFYLDAYVQQIDAVVAEIQQPVPPKQAAQVRA
KLLEIMRGETAMQLEQLSRKLSNILQTAESKERQRQRDVEEAKSVERLIV
MVSMLVSVAIAAIVAWRTSRAIAEPVITVTQVAEQVARKPNFDLRAPVTT
EDEIGLLAKSLNRLIERVSERTKELEQAKELAEAASKAKSIFLANVSHEL
RTPLNAVIGLSQLLKDDAADLSLSGEFTSDLETINSAGRHLLELINDILD
LSKIEAGKMTLYPEIFDVVTLINNVVLTVKPTIEKNNNILEIYCDEHLGT
MYADQTRMRQVLLNLLSNAAKFTTNGSIKLTVRREKEDFLAEMPFGAISF
TVSDTGIGMSPSQQLQLFQPFTQGDTSTTKKYGGTGLGLAISRHFCQMMG
GEIIVKSQPGLGSTFTVYLPLQEQS
>Ava_4354 PhoH-like protein
MADAFIIQLPNIPSAIALAGDREENLKILSRQTGATLVLRGQELHIYGTE
TQRDLATKLVRSLESIWIQGNTISSADILTARQAVDNHREHELQELQRDV
LARTRRGEEVRAKTFRQRQYIEAIRKRDLTFCIGPAGTGKTYLAVVLAVQ
ALLANQVEKLILTRPAVEAGERLGFLPGDLQQKINPYLRPLYDAIYEFID
QEKVPNLIERGIIEVAPLAYMRGRTLNHAFVIVDEAQNTTPAQMKMVLTR
LGFRSRMVITGDITQTDLPINQQSGLTVALQVLKHVEGIAVCEFTQKDVV
RHPLVQRIVSAYEQYEK
>Ava_0501 Histidine Kinase
MYEWILPSLSEVLAEGQGTVAECSPTKAEQQWRMSLAATEHLLINSLVAV
VPEALQGLVLAAPAPLFSQPILTQNLQTITFTARPFNPLALMPFQMPSAI
ASTESETTLCEPVLPLLPADPLASEQFCLIFTDKFRLVLVLATHKNGKKA
FSFSFEPEIVQQAWRSLGARVMLTNPDLFTELDSLVQQYPAIAPDYRTVL
QFSQFLLQELPEEETRDWGLGRTRGGEEQGNRIEEIPYPQCPIPNVQCPI
PNPPSIKPDVELLQAFAHEVRTPLTTIRTMTRLLLKRRDLPANVINRLEI
IDHECTEQIDRMELLFKAAELETSTSGKSANTHLTAMSLDQVLQQSIPRW
QQAAERRNLTLDVVLPQQLPTVVSNPNMLDRVLTGLMENFTRSLPAGSHI
QVQVIPAGDQLKLQLSPHTHCKDSNKASAPVTPPIRKALGQLLMFQPETG
TISLNIAATKHLFQAIGGKLIVRQRPHYGEVLTIFLPLEVSNKQNLTIKR
>Ava_0904 TspO and MBR related proteins
MNKSQNSGILEQLVNTIMGVKTGNQQQSPNTSIAATQELDIKAVVVYKLG
TILQIGAMILALMGMEQLIILIDNNSSFPNWFSTLLTALFFILLSIRSRI
FSLLDNTRSRQTYDQVIRPRWSPPPLAFPIVWMIIAVLRVISSVLVWQQM
NHQFLVTPFILFVVHLALGDTWNTIFTVERRLGAAVPVVILGPWLSALVV
TAIYWQTSPVAGMILSFSCVWLTVAAVLVLRIWQLNGSEPLYPVKLTPVE
E
>Ava_4682 WD-40 repeat
MLIDFGLARQFISGTVQQHTQSFTPGYAPPEQYAPIEERGEYIDVYALAA
TLYSLLTGQLPMPAPARLQNFTLQPPKDLNPSVSDRVNEAIMKGMALNYK
FRPQSVQEWLDLLGAGIVVPTQPVISSSNTYLSAKISPTQPITSVSQISS
SWECIHVIPAVSGKIAFSPKENILASVSSGGWDSNIKLWEALTGREIYSL
TGHSWSVYAITFSNDGQILASGGGDGNIKLWEVVSGQEIRTLTGHSWAIY
AVTFSSNRVVLASGSGDKTIKLWDLATGQEISTLTGHAESINSLAFSNNE
LTLASGSVDKTIKLWDLETGKEIYTLTGHSGTVNSICLSNDGQILASGSV
DKTIKLWDLETGKEICTLIGHLESIESVTISSDGQILASASVDKTVKIWE
MATGKEVFTLSHSSSVNSIAFSPDGNLLAAGDSGGNIKIWRRS
>Ava_1210 Multi-sensor Signal Transduction Histidine Kinase
MENSSTVKPIQTNSGPESQPDMKTALSGVISRIRQSLDIETIFQITVTEV
RQLLNADRVGVFRFYPELRWEGKFIYEDVGSEWISVLTSEFSDGLPPTLS
YHCFAEEFAQPYQQGTIKVIDNIYQAGISDYHIQRLEKLQVRAKVAAPLI
KGKELWGLLCVHQCSTPRQWEASEIEFVQLIAEHLGVALQQADYLEQVKA
QSAQLAQAKARETAAEWQRCMAIAIEKIRQSLDLESIFRTSTIEIRKLVN
ADRVAIYRFNPDWSGEFVFESFADGWISLIDEQEKKPELRKNVSECSAKD
LASTPTVDTYLQETRGGSFTKCEIYRVCNDIYNAGFSDCYIKILETYQAR
AYVIIAIYHGQKLWGLLAIYQNAGVRDWQDDEVYLLTQISTQLGVALQQA
EYLQQMQTQASEIAKAAERQRALANTVEKIRRSLDLDTIFKTTTQEVLSL
LGVERVAIYRFYPDWSGEFVADSIVDGWTPIVKPQPVTERLLLQEIQAGK
YARNEVFVPISQGDKLWGLLVAYQNSQPRYWQDEEINLLAQVGVQLGVAL
QQAETLQQLKVQAVQLAQAAARERKAAEREKALAATVEKIRRSLDLDTIF
ATSTEEVRRLLEVDRVIIYRFQPDWSGEFVAESLGNGWTPVNKLLTVITD
DCLQKSQGEYFVNGKILVVKDIYSQDYSRYHLALIEAMEARAYIVVPIFQ
GEKLWGLLAAYQNTQPRDWQEEEVDLLVQIANQLGVGLQQAELLEQTHRQ
KEEITQTLKELQATQSQLIQSEKMAGLGQLVAGIAHEINNPISFIYGNIT
YVTEHIENVFQLLHLYQKNYPKPKAEIQENITALDLDFITDDVPKILSSI
KFGAERISQLVLSLRIFARLNEAEMKMVNLHEGIDSTLLILQHRLQANTN
ILEIEVIKEYGDLPEIFCYAAQMNQVFMNIINNAIDALEKSILIGGIVDK
PQIKISTKFIKNNAVVICIADNGCGIPEAMRSRIFEPFFTTKEPGQGTGL
GLSISYQIVVEKHGGQIKCISELGKGSEFSIEIPIK
>Ava_1922 Two component Transcriptional regulator, Winged helix family
MIATHSPCVLVIETDDSLANQLSFDLQEAGYDAILASDATTGLQYCRDRQ
PALVVLDRMLAGESGLSLCKNLRNTGVRSPVLVLMARDTVDDRVACLEAG
ADDYILKPYRPEDFLRLIRLYLKPDVDTTEQLRFGDLILDLANRRAVYSG
RNVELTMKEFELLKYLMEHPREVLTREQILENVWGYDFMGESNVIEVYIR
YLRLKIEDEGQKRLIQTVRGVGYVLRES
>Ava_3471 Transcriptional Regulator, LuxR family
MMTFAKTSEQIEVSSKETKANFLQEVMERLEDGILIVTNAGEIVHANASA
YDLCCQLSQGSLDSNLIPPMIWKLCQLLLNTHNLYPEKNIILSDEIMLDK
SNTLRVRVRLIKLEQFITSCLLVTIENQYESLKSAALAEIRKYDLTPREA
EIWRLYRSHNSYKEIATQLYITINTVKKHMKNIHAKRQAFLAVHQ
>Ava_0362 Multi-sensor Hybrid Histidine Kinase
MKRDTTGKFVSNWDSEPKHRYSVSLTSTAWRSLDEEAHKQGISRSELIEH
FARHLGSEQNLTDEVISVNAGNAEQQPILATVFNQDINNHQQLQLVTSPE
TECQVTTILESITDAFVAFDENWHYTYVNQAAVKILHKTPVELIGKHVWD
EVFPELVGGVAYQELHRAVAEQVAVSWEEFGESVQCCLEANAYPFAQGVA
VYFRDITERKKAEAERERLLHELETERTRFEAVLRQMPAGVMIADADSGK
LVLTNEQAKQILRYNFEDSLELEEYVPVTPFAAFRCDGQPYTPYEYPLPR
SLLTGEVISQEEMLLRWEDNSHIFISVNSAPILNSQGQIVAAAIVFQDIT
ERKRLESELQQREQEFKMVAENAPDIISRVDREFRHLYVSPAVEAATGIP
PEVFIGKTNTELGMPEEICTFWHENLQRAFDTGQKQVVEFSFPTPTGLRW
YQSHLAPEFASDGSATTLVNIARDVTDYKRIEQALLDNEERLRLALTVAQ
AAQRQLATIFETSPVGIALLDSQQRFVAINQALAQINGLTRQEHLGRSIT
ELFGESDPQVVQVFHDIYTTGEPFISPSFAVNLPGRSDRQPGYYNVYYLP
TTNSNHQVEDVLVYVLDVTEQVRLERGLRFLSETSKVLASSLDYQTTLER
LAQLAVPELADWCTVHMVAENGSVEEIAVAHVDPAKLAWAEEIRRKYPLN
LNDPRGAALTLRTGQSDLLIDIPDELLVQAARDPEHLEILRQVGFKSAMT
VPLRTQTRTLGVISFICAESGHKYDQSSMQLAEELAYRASLAIDNAHLYR
LAQSDRTKAEAANRIKDEFLAVLSHELRSPLNPILGWSRILRTKQLSPTK
VDQALETIERNAKLQAQLIEDLLDVSRILQGKMTLNVAPVNLAATITAAL
ETVQLAAEAKNIHIQTTLKPIAGNVVGDQNRLQQVIWNLLSNAVKFTPSG
GQIEVQLAQVNLYAQIQVKDSGKGIAREFLPYVFEYFRQEDGATTRKFGG
LGLGLAIVRHFTELHGGTVHVSSLGQDLGATFTVRLPLNLVEQELPADDE
QLKKVTDLTGTHILVVDDDADMRELAEFILIQFGAQVTTAASAVEALNIF
SHFIPDLLLCDIGMPEMDGYSLMRQIRQWLPHEGGTIPAIALTAYAGEIN
QQQALAAGFHQHISKPVEPEELVQTIFQLLHPVQ
>Ava_1175 Histidine Kinase
MNANITENLFAALNIVVLERINDGLFKIISNLPSWFREFCQHKYSLGMEI
SILQEEFYFLQNFLFDAEEFWSNSNCKNLTSGIWIQIDPQGKEYQFEARA
TFVEDKKILLIEVLEESYRHRQNIIQEARQRQLNYQKLIKNNQKQEILIH
CLIHDIAGQLNAMNGCLSLLEFENLTPQGRNYLEVCQQQSFNQENLMRKV
LDTFSAEMMALENFVVDSEEAPNILSCVNDVVETLKPSFTLNNINLILAD
AIDPLADWKVQGDKSRLDRVIFNILENAVRYSPPESTVIIRLQSKENYVY
VSVDDEGSGVPLETVNTLFQKFSQGKDKSSGKSGLGLYFCRITVERWGGS
IGYVPRSEGGSCFWFCLPRFLS
>Ava_2070 Anti-Sigma-factor antagonist (STAS) domain protein
MSFLAFVELAIYLVKFMTLTQEPQVVLFKPQGSIDLQGGLALTEQMTQAG
SQPHQLWVLDLAEVDFMDSSGLVSLVKGLTSARQLGCRLILCNVQTPVRL
ILELTQLDSVFEIFDSYEEILTLVNDSSFALVS
>Ava_3584 Serine/Threonine protein kinase
MLQLLDRYVPLQTLGAGGFAQIYTVWDEKTQTEKVLKVLIEDSPKALELF
TQEAEVLVRLRHPGVPKVEADGHFQVNLSNPKPRQLPCLVMEKINGPTLE
EMLNKYPQGCPENLVLNWLTQGIKILQELHKHQIIHRDIKPSNLMLRTPS
PSVISQGGTGWEQLVLIDFGGAKQFNTGRQRQESSSTRLFSSGYSPPEQV
TGGHIGPSVDFYALGRTMIELLTGKYPPELEDPQTGVLHWRNRVTIRPEL
ADLLDEMVHEDVRSRPANAAMIQKRLTKINQPASGQNNFQQWLTQLANQL
ALLNQSTEQVFSNLGQTLGKILRWIAQTIVKIITACFSTIWAMLLTGLGA
SVGTIAGFILAYRTNLGDRLIEFIASQLPELIPNPESGFGAEIIVFAAAG
LGTAWGLTASGCFAQRRRFLVASFMGIISYAFGWLLWQIITSTADSGEGL
VGATSIAVFLLALSMSFRSHHIVYAMIGSFGTAIVVAILIVLGFPTTVLQ
FSNRHLWSELSLPIIFFSSIGILMSFWLGVSYYLIVPGLRFLGWR
>Ava_1945 Periplasmic Sensor Signal Transduction Histidine Kinase
MINKGWRWTKSLPLASRLFVSHLVVMIVGLISLVIISRVSSPRFFVLHLE
RLESEGVNLINVRADLVQGFEIAWRSSTIWSVLVGSTAAGGLSYWVSKRI
MQRLTEMEQITQQFAAGHLQARLPLSDIPELNRLGTSFNRMAASLEGVEA
RRRELIGDMTHELRTPLTVVRGYLEELADGEIEPSPEVYRRLAKETKRLE
RLVNDLQELSKAEAGYLPIRIQSVNLYPLLESLVERFSDQLLEDGPVLLA
EFTPQIPLVLADIDRTEQILVNLLGNAIRYTVKGSITIRTWAENRQLWIA
VIDTGIGIASEDIPHVFERFWRADQSRDRHSGGTGIGLTITKHLVELQGG
EIHLDSELGIGSTFRFCLPLA
>Ava_0304 Protein serine/threonine phosphatases
MENDAATLYCPNELCQAANPLTHKFCQRCSTPLPKRYLWVVGDSLSIGST
GEILADRYLIINQSVVLDTKPGLLPQAPDLENTHPIRPYLRLIPYRLNIP
QVYGVLPATDGCVQSQVLLLEKSPLFADNLAQQVHLCSEFTDAWRYATSM
RQLHWLWQIANLWQPFKSEGVVSSLLNPYLLRVEGPLVRLLELHSDPTTA
LELPQLGEFWQQLHQEAKPAIAEFVQQISYLLIQGEIKSSEVLVAVLDRG
LAELSKSQTPTIQIATKTDTGPSRQRNEDACYPPSGTLLSKPPQPTALAI
VCDGIGGHEGGNVASNLAIETVHKQVQQLINVPPDHIEPSLLIADLERAA
AVANDKISQRNDSENRQGRKRMGTTLVMALPIAHEMYITHVGDSRAYWIT
RHGCYQVTLDDDVASREVRLGYAVYREAVQQGGSGSLVQALGMSPSSSLH
PTAQRFILDEDGVFLLTSDGLSDFDRVEDYWETEILPILTGEENNIVNVV
ERLVDIANTKNGHDNVTIALVNCQVKYTEPQITLKAVVPDSTHIKTVNLT
SKALQPTLLEAKPEQKTQVVPSNLPNRISKLPLNLIVPLILVATAGVLGY
WVMLLRSQYAIPTVTPTRTLPSATQSPKVQQRSLNNLAPGWIIKTNSEIT
FNQQQVPPESFLEVIDKKFNPQPAPGIYEVYLRLCNPQPASANNLATEPP
PPSDQPIKTELAQLKRFAVTVLQPSQDSPCNSVSLPADIPPSAANTPNNP
GAAESNNR
>Ava_0828 Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with Phytochrome (GAF) sensor
MSKKSPRAKACSCHNITCCPAKEAGKLFLWFPIPHTLKKVTDYLQKLAIK
FELMGERPGLGLGCRAGQAQEIAHSVAQILTSRELKETQVLFIRGAIQPQ
LQDFSDISSLQRFVKFSQSDWLVEMLAQERFTSHFQPIVSMKNTSEIYGY
EALLRGLDEQGNLIPPQPIVELATEAGLLPQLDRIARLSTIAQFSSHQVS
GQIFINFAPTAVYDPASCLKSTVEAIDQAGISHERVVFEVVESDSPQDLD
HLKAVLKYYRDAGFSIALDDLGSGYSSLNLLHQLRPDFIKLDMELIRDVH
QDLYKASITEKLLEIAQKLNIRTVAEGIECIEELNWVQERGATFAQGYLI
AKPDIVPVTTTPHFDTNTSTLVLHCSKQVEQFVQHQSESERIVAAVTQRI
RQSLKLEEILQTTADEVRQLFEVDRVLIYRFEPDWSGLVAVESLTEGSMS
ILGFHILDTCFQSTHAAYYQQGNTRAMEDIENAGLSPCHLQLLQSLQIRA
NLIVPILQKERLWGLLIAHQCTSTRQWQQSEINLFNQLASQAAIAIQQSE
LYLQLQQANLELQRLACSDGLTQVANRRCFDNTIALVWEHLAREQGSLSL
ILCDVDCFKLYNDTLGHLAGDDVLRHVAGAISRSVKGPSDLVARYGGEEF
AVILPNTDAEGAIAVAKEIQSNVSILQLPHPSSQVSELISLSLGLATTIP
DSQSSPAILIAAADQGLYQAKAQGRNCLVQVERI
>Ava_B0029 Two Component Transcriptional Regulator, LuxR family
MIRVVFIEDNDIIRLGITTAINQQPDIEMVGVGHTGNEGVELVKSLSPDV
ALVDIGLPDISGIEVIKQIKKSKSNTKVVVISCNSCQEVITAAISSGADS
YILKKNNTSLIVEAIKSTYNNKSLFDSEIIQRGLLKIFPTQKAKGKIFDD
HLTQREISVLALIAAGFSNKQIGEKLFIGENTVKNHARNIYSKLGVDSRI
NAILKGSELGYISNTATQVI
>Ava_2044 TspO and MBR related proteins
MKARWIITAVSAALFFGGSLFTSLRDPWFQNLQRPDWLTFEFLIPFIWTF
IWACTTISAIIVWEKRTRQGFRPWYLMAIYAAIAISTSAYSPIVVELRSL
TGGIFMGGLATLLVYILAFLVKPISPKASWLFLPYALWGPFGTYLTWLLL
QLNPGVAN
>Ava_3009 Histidine Kinase
MQQYSSLPEHNSSIDTTPTLLAKSQQLCAELWLERSLNQLQTRLLNCLES
AFNSVPTRTTEADIFQTVVNELDIALNNSNVGFPLCAVGIALLQPQAAVG
KVYYISRPLSLGCQPPLLEEISKDGKKLRLQLQEAIKITDLQKLEKQQPP
QAWQLRDDADGVIGWLLLATDNSKPHENAFTAPHPQLNTQLMERSAEQCV
KALAHLKKIQSLQQKSQNLGISNQELERTNQLKNQFLANTSHEIRTPLSS
IIGFTHLLLAQGYDPTRERHHEYLNIIQSSGKHLLALINDILDLSKIEAN
QLEVQWEKVNVPELCQNVLTLIKEKAANKGVKLSLELDPHIKTFVADPLR
LKQMLLNLLFNALKFTNQGTVGLKVTQRESFIHFTVWDTGSGISPENLAL
LFQPYFQIPNSSVAQHEGTGLGLVVTRKLAEIHNGSVEVESQVDHGSRFT
IILPLQQNGQVLVGEDMEDEETTSPASLTPNSSKDILLVEDDLPNGELMQ
THLSKLGYNVTWVKNAHEMWAKLDQQQAAVILMDIRLPDGDGLDLVKQLR
EKSQYQQIPIIAQTAMAMKGDRSICLSAGVNDYISKPIDLNLLASLVAKY
SQL
>Ava_0063 conserved hypothetical protein
MNKSLPTHFQESIYQELLPSLQIESVNPRNLIQVTYVPQPWLLLGKGNYA
AVVYHPDYPEFVVKIYAPRRPGYEEEVEVYHRLGSHPAFSECLYAQDGFL
VLKRLYGTTLYDCMHLGLPIPKQVIRDIDEALEYAQSRGLYPHDVHGRNV
IMHEGRGLVVDISDFLHQEPCSKWHNLKKAYYWLYLPVLRPLRLPVPYSA
LDWIRKCYRLGTLCKQLCRQLAPKLNCFQYLRRY
>Ava_1263 Two component Transcriptional regulator, Winged helix family
MGSVCIEIVEGNPHLRSLLGWHLQQLEYRVHQAASIYQAREAFLSHQPTL
VILDADLPDGDGIEFCRWLHRQQQPLILMLSARTNEADIVAGLKAGADDY
LSKPFGMQEFLARVEALIRRKRTPTAPAYLDYGTLQIDLVQRRVRFQGEF
IDLTPQEFSLLYVLAQAGGVPLSRSELLRRAWPDAIDNPRTIDTHVLSLR
KKVELDPRQPSLIQTIRNVGYRFNMEILNANPPQTQAKLTKERFSNQRST
LSGQRV
>Ava_1102 Response regulator receiver domain protein (CheY)
MNYHGTFTALSPQGLLRHLSSCFDTTCLKAFSNSVTWSIYLEDGTITYAT
HSVEPFDRLERHLRRLSQQFPQVTNEIRVQLRLLFEAEGQNSSDTIQPPD
YQAVHWLVEQEYLDTAQATMLIQELVKDVIESFLLIKNGNYELSNSLEKV
SGICRLDAAKVMERCQIRLQNWQSYLPKITSPYQRPYLLINSKNSPELQP
KLTYWMKGFSLRHLAIIMNQDEIQLAQNLYPYILTGEIILHEPDPPFDQL
PKILAESTLTPKYTTAFLSRKLVDTVVELSSNATPITPILAVDNLAPVVR
LPQGYTPAKASHQELTLSNTTNSIPERVTPATRTTRQVYKIVSVDDSPTI
LKEISYFLESENFTVITINDPLKAAMSIIRHKPDLILLDLNMAGIDGYEL
CKIIRNNSMFKNTPIIFVTSYKGLVDKVRARLAGASGYLTKPFTRAELLK
IVFMHLA
>Ava_0083 Serine/Threonine protein kinase and Signal Transduction Histidine Kinase (STHK) with GAF sensor
MITLPNYKILELIDEGVKTNVYHAISIPDGKLVVIKILKKEYPELKDIAA
LKHEYELIKNLDIPGVVKAHSFEKYNNYFAIVLEDFDGTCLYKVIQEKKI
GLLDFCKIGIQITQALGELHQNYIIHKDIKPQNIIVNLETNQVKIIDFSI
SSLLFQEKAKLNNPDLLEGTIAYISPEQTGRMNRSIDYRTDFYSLGVTFY
EMLTGQLPFVVTDPMELVHCHIARQPTKINELIPEIPEVVSDIIMKLLSK
TAEERYQSAFGIKADLEKCLNQLIESNSITTFIIGQHDYSSQLQIPEKLY
GRKTEIDILMTAFENVNQGNKELILVAGYSGIGKSALVNEIHKPVIKSRG
YFIAGKFEQFQRNIPYASVIQAFQELIQQLLTESEQQLANWREKILEALI
PNAQIIIDVIPELELIIGKQPEVPQLGSAEAQNRFNLVMQKFINVFAQKE
HPLVVFLDDLQWADLASLKLIQLLAINSDIQYLFLIGAYRDNEVDDSHHL
MLVLQEIEQKCIPINIIYCQNLKITDVCQLVSDTLKSGLEESKELAKLIF
HKTAGNPFFVNQLLKFIHQENLLVFNFITGQWQWYIQYIQMLDITDNVVD
LMIGKIQKLKDNTQNIIKIAACIGNRFNLNTLSCINEKSHNATALDIWEA
LQAGLIIPLSDNYKLPQLLDDVDVFVIDYKFLHDRVQQAAYALIPDEHKK
GIHLNIGRLLLKNINKSLLEEKIFDIANQLNMGAELITVPEERYKLASLN
LMAGRKAKDSNAYESAVSFLKQGLTLLDIDCWQNYYELTLDLHVETVESE
YLNTNFEEAEPLLATVIANSKNILDTVKVYEKKIQFYVGQNRMREALDLD
LQVLEMLGVSLSQTPPTELKIEELINLPEMIDPSKLAAMRILMTAMPPAY
LADPALLPLIAFTMIELCLQYGNSSFAAYAYGFYGLILCGPLKNIESGYR
FGKLSLQILNQFNAKEIKSKVYALFNIFVRHWKEHIQTTIEPLQEGVKSG
LDTGDIEYVGYNGLLVCWHPFWSGENLETVEQRLDKYINLAQKIQQEHFT
FCLLILKQLITELKQGLKNEVYLDGDDFNDSIMQRMAGNITAIFYAYLAK
SMLSYFFKDYSQAVKNAELAQQYEVAVGGTFYLIEYKFYYSLGLLALCLN
TTSDADIKSALEKVSENQQQLKEWADHAPANNQHKYELVEAEKARVLGQV
LIAMEYYECAIQGAHKFGYIHEEALAYECAAEFYFSLKRNEFACLYITKA
HYGYRHWGAIAKARNLESKYPELTAKISNQYPAGFINTNITTSTASEKSG
GLDLITVIKASQTLSEVILLDNLLEKLMTILIENAGAQTGILLLEKAGNL
LIEAKASVDKDDITVGQSIPFEDSQQLPISVINFVRRTRKDVVLSDASNE
GSFTLDPYIVKHNIKSIICTSILNQGKLIGILYLENNLIVGAFTADRIQI
LKLLSSQAAISLENAQLYANLEEKIEERTRELNENNLRLRQTLHELKLTQ
TQLIQTEKMSSLGQMVAGIAHEINNPVSFIHGNLSHIDNYANDLLTLIDI
YQTIYPEATPEIEEFLENIDVDFIKEDMPKTLSSMKIGTQRIREIVLTLR
NFSRLDEAEMKAVNIHEGIESTLLILQSRLQAKPGKPAIEIIKNYAELPK
VECYTGQLNQVFMNILNNAIDSLEKLNQEHNLEEIKTDPSAIAIRTEVVN
PDLVAISIKDNGLGMSDSVRKRIFDPFFTTKPIGQGTGLGLSISYQIVVD
KHRGTIECISTPGQGAEFIIQIPCRQKQVI
>Ava_0638 Putative diguanylate cyclase (GGDEF domain) with PAS/PAC and Chase2 sensors
MSKQLGNPIVRLILGLKQWLSRGRRELITASVVLVCVLILRSIGLLQSVE
LSALDQFFRLRPNEQPDNRITIVAIDEASLHKGFPIPDGIIANLLKKLQA
NQPRVIGLDIYRDLPTKDGHENLVDTYKTIPNLVGTQLLSNDKSYKVAPP
PQLNSQQIGFNNLLYDPDGKVRRILLYWHIGENYYESFALKLALLYLKSE
KVFPRKAANNPEYLQLGKSVFPRFEQNDGAYVRADDKGTQILSNFPKPGC
RNSSLDSCGFQKVSMLDVLDDKVPRSWIEDRIVLIGSTAPSLQDFVFIPY
SSRWMRAAKPVAGIELQAYFISQLISAALEGRPVLKVWSDFWEYLWIFAW
SYLGAVAAWRIRGKIPNIVAIFVACCLLFLSAYLAFLSGWWIPLVPALLT
LVGSVIWMINYLAHMQEELKRSKEFLQQVIDTIADPIFVKNEQHQWIVLN
KAYCRFIGYPESFLVEKSDVDFFPKHEADVFRQQDELVFDTQKPQENEEE
FTDAYGKTHLIATKRSLHKDAAGNLFLVGVIRDITQRKLMEEELKRTAAE
LFRSNNELKLKEDHLRYLAYHDALTGLPNRKYFAEQLYESINWAKDNNFS
LGLLFIDLDGFKQVNDSLGHEMGDRLLVVIAQRLSNSLRASDTVARLGGD
EFTVILQAIPNVQVAAKVAEKILANITEPIVLNGCTTKVSVSIGISIYPE
TSLDPDTLLKKADAAMYRAKHLGKNRFELADRGNTES
>Ava_4580 Anti-Sigma-factor antagonist (STAS) domain protein
MIQIEQNSYTTQDGNTVIVLKPTGRLDITTAWQFRLKLQECISKLSHHVV
VNLGQVNFIDSSGLTSLVAGMRDADKVNGSFRICNVHPEAKLVFEVTMMD
TVFEIFETEEEALEGVPRSMAS
>Ava_3779 CheA Signal Transduction Histidine Kinases (STHK)
MMTDTEIREQGYIYFLAEAPDLIQTIEQELFSLAENHSVARVHNLMRATH
TIKGGAATVGLKTIQMIAHSLEDVFKALYSPKVVIDAELQTYLFQSYECL
QLALTSELTGSIINEEELLQRATDIFAKLQEKLGDNFGDDSHIPTSEELG
FDIVQSIFEVGVQQRLGSIIEALNNIEDDTELIDFFSSQLEVFVGLAESL
NLPGFGEIAQTALTALQANPSQVRQITEIAHADLEQAQRNILAGDRTHGG
TPSAALQQLTSVVTNQASGEVNSEFLIRQEEFYQFLTTLNNNKSECLQPV
TAQLYLKVVHYIFGWFNHEREIPESALKWDLLITNNEFSSSIEYIESWLG
KFLEFVQQEVDSKGLCLYRQGIILIILLAIVKFQYSVKKTADSILLIQAI
QTKIALVAQEYKQYPPITAQEKNWTDHPKLQQLLVFKDISTSSSNINDGL
LEAIWGGEANEDDTQVEPQIEVNDISESTTSLAVAEKLSTEITETALDVV
NESTIDKVKNHQGKKVHKSSSVRVEVEGLERINYLASELLINQKRRTLND
EQVQEIIEQLLQRLNKHQETLNQLRDLPLQRQSLATQHTQSFASVNFDPL
EMDAYTEFHLTLHEAIEETSQLQEATESIDFLFKQATQISHKKQNLAFSL
IDNLVEARMLPLENILSRFPHMVKNLSTVYHKRVDLKFTGTNVLVDKAIA
EKLYDPLLHLVRNAFDHGIESPEVRRERGKPEQGVIEIWAYHQGSQTIIE
VRDDGQGLKLDSIRKKAIELNFISNKDQSKGHLSQINDSELLEFMFAPGF
TTAEKVSELSGRGMGLDIVRSQLQALNGSISVQTLPNQGTKFILKIPFSM
TTDQLMLVQAGGVVYALLLDSIEKIVIPSAQQIQEFEGKRVLHWDSGNED
TMLSLHQLSELMYYNGGCFNNLNTSNLLPEHNTEEINHPVLLLRRNQGIF
ALQVDQIIGEQELVIRPLGNAIAPPKYVYGSSSLANGNLMLVIDGALLLE
SVEMQATLDTLALPADEYANQKALSISPSTIPSLPLLSATVETHHKLSKV
ILVVDDAISLRQTLSLTLQKSGYQVIQAQNGAEALEQLQRHPEIQLVVSD
LEMPRMNGFEFLSHMQHNPKYTKLPVIILTSRSAEKHRQLAQELGAKAYL
SKPYLEHELINTIESLINSAKDNLNRLLTV
>Ava_1004 Response regulator receiver domain protein (CheY)
MIGSNTQPLLVIEDSDEDFEALQRVMQREVVLNPVFRCTDGEDALDFLYH
TGAYLDPATAPCPSIILLDLNLPGTDGREILAQIKQDHNLKHIPVIVLTT
SCNPKDIEICYQYCAASYILKPIDINRLVKTIQSFLTYWLDIVILPDAVS
N
>Ava_4696 GAF Sensor Hybrid Histidine Kinase
MATEHLTRESDELDLKQLLKTLTAVKKGDFSARMPIDQTGIAGKIADTLN
DIIDQNERMAAELKRISTVVGKEGKITERASLGNVRGSWSDSVNSVNTLI
TDLVQPTAETTRVIRAVANGDLSQTIATEIDGRPLKGEFRQTANIVNTMV
TRLSSFAGEVTRVAREVGTEGKLGVQAEVQGVAGTWKDLTDNVNLMAGNL
TGQVRNIAEVATAIANGDLSKKITVDVKGEILELKNTVNTMVDQLNSFAS
EVTRVAREVGTEGKLGVQAEVRGVAGTWKDLTDNVNLMAGNLTAQVRNIA
EVTTAVANGDLSKKITVNVKGEILELKNTVNIMVDQLNSFASEVTRVARE
VGAEGKLGGQAEVRGVAGTWKDLTDSVNFMAGSLTAQVRNIAEVTTAVAT
GDLSKKITVDVKGEILELKNTINTMVDQLNSFASEVTRVAREVGTEGKLG
VQAEVRGVAGTWKDLTDNVNLMAGNLTGQVRNIAEVATAIANGDLSKKIT
VDVRGEILELKNTINIMVDQLSSFASEVTRVAREVGSEGKLGVQADVRGV
AGTWKDLTDSVNFMAGSLTAQVRNIAEVTTAVATGDLSKKITVDVKGEIL
ELKNTVNTMVDQLNSFASEVTRVAREVGTEGKLGVQAEVKGVAGTWKDLT
DSVNFMAGSLTAQVRNIAEVTTAVANGDLSKKITVDVKGEILELKNTINT
MVDQLNSFASEVTRVAREVGSEGKLGVQAYVRGVGGTWKDLTDNVNSMAG
NLTAQVRNIAEVTKAVANGDLSKKITVDVKGEILDLKNTINTMVDQLSSF
ASEVTRVAREVGTEGKLGGQAVVQGVAGTWKDLTDNVNSMAGNLTAQVRG
IARVVTAVANGDLKRKLMLDAKGEIETLAETINEMIDTLATFANQVTTVA
REVGIEGKLGGQAKVPGAAGTWKDLTDNVNELAATLTTQLRAIAEVATAV
TKGDLTRSIAVEAQGEVAILKDNINQMIANLRETTQKNTEQDWLKTNLAK
FTRMLQGQRDLETVSKLILSELAPLVGAQHGVFYLMEGAENQSYLQLLST
YAYRERKHLANRFQLGEGLVGQCALEKERILLTEVPSDYVKISSGLGEAN
PLNAVVLPVLFEGQVTAVIELASFRRFSEIHLTFFDQLTESIAIVLNTIA
ASMRTEELLKQSQSLAEELQTQQSELRETNKRLEQQAQSLKASEDLLRGQ
QEELQQTNAELEEKAELLAIQKKEVERKNREIEQARRSLEEKAEQLALSS
RYKSEFLANMSHELRTPLNSLLILAKLLTDNVDGNLTAKQVEYSQTIYSA
GNELLALINDILDLAKIESGTMSIHATPIPLSELAEQIERGFGQVAQNKG
LTFAVELAPELPTTVNTDIKRLQQVLKNLLSNAFKFTERGEVRLKIEVAK
PGWNSNQQPLNSAQNVIAFAVSDTGIGIAADKQKIIFEAFQQADGTTSRK
YGGTGLGLSISREIAHLLGGEIKLTSYPGQGSTFTFYLPQFSAESTLTQA
DAINRVSTKYDSILVDDRTNITNSSADNNILLIIEDDVNFARILVDMARQ
HGFQVLSAQTGTAGLKLAKDFQPMAILLDIRLPEMDGWTVLDRLKHDPTT
RHIPVHIMTVEEGRQRGLQLGAIAYLQKPVTSEAISEALDKIRGFVERRV
KNLLVVEDDELQRQSIVELIGNSDVATVAVGTGAAALEAIRTQQFDCLVL
DLGLPDMTGFELMEQIKREANGATLPIIVYTGREISKTQETELRRIAETI
IVKDVRSPERLLDETALFLHRVQANLPTPKREILEQLHSQDYSLVGKKVL
IVDDDVRNIFALTSMLERYQMQVIYAENGREGISLLENTQDIDVVLMDVM
MPEMDGYETMQLIRKKEQFRALPIIALTAKAMQGDRDQCIAAGASDYIAK
PVDTEQLLSLLRVWLYR
>Ava_3369 Two component Transcriptional regulator, Winged helix family
MYTSESIKYSARTEIGQTSRILVVEDEELIQEMLAVALEEEGYGVVTAAD
GRSAVEYLKSFEPNGGDFPFDLVILDLMLPQINGLDICRLLRHQGNPVPI
LMLSAKGSETDRVLGLEVGADDYLTKPFSMRELVARCRALLRRQRLITLP
QLPVLKFKDVTLNPQECRVLVRGQEVNLSPKEFRLLELFMSYARRVWSRE
QLLDQVWGPDFVGDSKTVDVHIRWLREKLEQDPSHPEYIVTVRGFGYRFG
>Ava_2771 Multi-sensor Hybrid Histidine Kinase
MPNIPISALLRFGIVIFSVALACALMLLLDPWLGMTSTPFLLFFSAVMFS
AWYGGFWSGVLGTFLSVILSNYFFFHPRYTLSIDTDNVVIIGLFAVQGWF
FSFICEILRNTKKQDAVNLQKLRQSEERFRLALSNSDIVVFQQDRDLRYR
WIHNYQGVASAEEIIGKSDNELFPASVAEKLTAIKQKVLEKDVSVHEEVS
VIFHGKVVYYDLLAEPLTIDGQIQGITCAAVDITERKRSELEKAKLQSKL
QKAIEQQDEYLALLNAWLASSPVALAFLDTKLRYVYTNEALAAINGVPQS
QHIGRTLREVLPEWATQLEPILQQVMATKQPLVNQEVCGVTYPSGVHRCS
LVNYYPVCLPDGKLLGVGVTALDITERKQAEDALRYIAQTSNTLSSSLDY
EQTLAQIAKISVPQLADWCSIDIINQDGSIRRLPIAHVDPTKAELARLFQ
EYAPQLGSGSLVANVLQTGEQLLVADLPDSPLPADQNEENLELLRQIGIK
SLMLLPLIAHEQVLGCITFVSAESGRSYNQSDLSLAKDIAYRAALAMENA
QLYRDVQQALKHYAESLALLDALLAGAPVAVCFLDKELRYLRINQVLADL
NGLSIEEHLGRKFQDVLPKMAEQFEEQLQQVLETGQPLLNLEVSGEALGR
PEINSYWLGNYYPVYDGMGKTVGIGIILADVTATKQVEIALRESEERFRA
MFDQAAVGITLVTLDGQFLQNNPALCDITGYSSEELSQMKFPEITHPDDV
EADWAYAKQVLAKEINGYSLEKRYLRKDGTTVWVNLTASAVWNEQGEPKY
ALGIIEDINERKQAEAAQNFLVEASTILAASLDYEVALNNVAHLAVPTIA
DWCAVDILQADWSIKRVAIACVNPAKLEIIEEIRRSYPTRTEGKHPFRDK
LLKGASAFYPELPNSILVEIAQDEQHLQLLQSLEMRSLMVVPLYSREQIF
GVISFVTGSSGRQLKQTDLALAEDIARRAATAIDNARLYQETQQAKQAAE
LAMSRMLRLQSITAALSEALTPQQVADVVVNQGLAALGASAGSVVLLTEG
GTTLKIIQAIGYPESVQDAWETFPLTATVPIAETARTGEAIFLANVTEFA
AKYPQIANVPSLTGNCAFACIPLIVEQQTIGVMALSFATAQKFNEEQQKF
MLTLGQQCAQAIARSQLYEAEKNARAVAESTNRIKDEFLAVLSHELRTPL
NPIMGWAKLLRTRTYKEETIKQGLETIERNAKLQTQLIDDLLDVSRILRG
KLNLNVCLVDLRNTVQAGLETVRLAAEAKSIAIHTILSDEPVQVMGDGDR
LQQVIWNLVSNAVKFTPSEGRVEVRLEQVGRDAQIQVIDTGKGITPEFLP
YVFEYFRQADAKTTRVFGGLGLGLAIVHHLVELHGGTVVAQSAGEDQGAT
FTVKLPLHKSADYQVQSAKSAVTELENQDSLLAGVQILLVDDQEDVREFF
SFALEQCGATVTAVASAIEALEALARSKADVLLSDIGMPQIDGYMLLRQI
RKWSPEQGGQIPAIALTAYAGEIDQKQAIAAGFQKHIAKPADPVELAEAI
TQLIGRK
>Ava_2519 Serine/Threonine protein kinase
MIGYILRRRYKIIKQLGSGGFGETYLAEYPQDLPVSPQYKCVVKRLTRPQ
TPDLDTEERFKREAAILFRLGKEHNQIPELYDFFEENREFYLVQEYIDGH
DLSYEMEQGKPWSEADVIQLLQEILEVLDFVHQNNVIHRDIKPLNLMRRY
SDNKIVLIDFGIVKEISALGVNAQGKISSTVPIGTRGYMPSEQFHGHPKL
CSDIYAVGMTAIQALTGLPPQELHIDPDKLEVIWREKAQVSNILADILTK
MVRYHSKLRYTDASAVLEALKQTQFSLQTSANSPKLKVSNQSQLLLLLLK
PIQIADKYGYIDQSGQVIIQPQFNEAHNFAEELACVQFDNKKYGYIDLSG
RVVIEAQFHEAWSFSEGLAVVQIGDKYGYIDKNGTLVIQAQFDYAHDFRN
GRAMVEIGKQKYHINKMGNFIKIIGMLFQNQMK
>Ava_0615 Two component Transcriptional regulator, Winged helix family
MTAHILLVEDEVKLARFVELELSSEGYKVSVAHDGITGLTLARESTPDLA
VLDWMLPGLSGLEICRRLRATGNSIPVILLTARDEVSDRVAGLDAGADDY
VVKPFSIEELLARIRAHLRRTQETDEDLLQFEDLSLNRRTREVFRGNRAI
ELTAKEFDLLEYLLSHPRQVFTRDQILEKVWGYDFMGDSNIIEVYIRYLR
LKLEEHNEKRLIHTVRGVGYALREYPNK
>Ava_3886 Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine
MSKRVFGRWCLVLSLICLLLTGCSGNLSQEKTLRIATEPAFPPFEFTGQG
GNLQGFSIDLMNAIASAANLRVSFQSLPFDGIIPALQSRTVDAAISSITI
TAERAKTVAFSRPYFKAGLAIAIRSSDEDITGFDSLKNKKIAVQIGTTGA
EKAKSIPGAQIRSFDSAPLALQELLNSNVDAVINDAPVTLYAINTGNLQG
IKVVEKLLTEEYYGIATAQNSPYLALINDGLNRVLTNGTYSQIYQKWFKA
EPPSLPDKSLYENQNNTRKSSSIKLILQFLPTLLQGALVTIQLTILSTLL
GLICGTLIALIRLSQFTPARLLARAYVDFFRGTPLLVQIFMIYFGIPALA
QQLGFTFNFDRWVAGVIALSVNAAAYIAEIVRAGIQSIEIGQTEAAKSLG
LNPWLTMRLVIFPQAFRRMLPPLGNEFISLLKDTSLVAVIGFEELFRKGQ
LIVADNYRAFEIYAAVAIVYLCLTLLASQVLSRLEMWMNPTMKAQQRKAK
R
>Ava_2150 Response Regulator Receiver Signal Transduction Histidine Kinase
MLDTSTETSFILVVDDTLTNLEIISEALIGAGFEVATAVDGKKALEQIQS
RVPDLILLDVMMPVMDGFETCKNLKIQPETHDIPVIFMTAITDTNSKVEA
LSLGAVDYITKPFHKAEVLARISAHLQLRSLNKNLEKRVIERTAELNQAL
KDLQEYQLQLVQQEKMSVLGQLVAGLAHEINNPVSCIYGNLGHALTYFEN
MDKLINLYQSYYPQPVQEIQNEISEMDLAYVRSDLPNLIFSMKEGIQRIR
DISRSLRIFSRSDTEKKIQFDIHEGIDSTILILKHRLKGSENHPDIEIKR
DYGVIPQVNCFPGQLNQVFMNILANAIDALEESFSNNYYSVIDSEITVNQ
EMMAETPQIIIQTILSEDESYALIKIKDNGIGMPQQIKERIFDNLFTTKP
VGKGTGLGLSIARQIIIQKHGGKLEVNSEPGRGSEFIINIPIE
>Ava_C0185 conserved hypothetical protein
MTIQAKHFDTRLNQWIHTDGNTNNPDSLLKEELNNTLLEYFFPGVNFSFG
HMDEKSTVEQLTNHPEGNKLLLSSKTRLLYGPEECLDTIRQLCPDNKDRG
AYGSIFLGSCRNAVNKELNILIVDDNNGENGGIISNDQAYRLTGDCYGQI
SKELYHELTKHQKGDKYRVIQHRFGWTDRDGDDQKYRFGKGTLRPANLEQ
ILNYQDSNNSTKIDLILPLSAFKGTDKDNPNSPTKPQIQPGLYRQNIWLG
EKSQSELGKTAISQLLASFPNGLKDFTEQLELEAKKLKEAQDDPRQLAQL
YCEKYEKRKAFLEEQATTLEEQAAEDPTVAEELETLRDRIATDSFIYKLI
KADLQGERQLLETEKVQRELARFVQNEWKEIAIGKTLTFERAMVIPSKDL
QNGEISIPHYQDGEEVLNFRSPFLNSNGLCVSTNKIVEDILGPDGQPLAG
AIAVSDETSDRIYNRLNEQIKSILPEAQGKNIQLAGIENYLDQSISKLET
RDKIEFTNKFNQYILELKSAGYELEILPQESEQERQARDYDGDCIGFERA
SKYPNLTIEAKERNLPENAYAPTVKLKKQSFYQEDGSQAEFEEIAIHMSD
GISVGVINNHLTAIEALESEITILKNFGSEKDSIEYVQQVAKHYEDLFKT
EVWAKSKGIEGKEIPTKYRSYMEEFIKTVRQEPTNTLVAMNINTQMYREM
IAEAAFQNQIAVDLFKSAKKPEIEIIRNNSRILHREVNYIKDKKKDVYID
NTIQPTGYSPVELLIAQTNQYFEKARLESREIVQFQALFKGVEFSHEQRL
RATLIKKEFDKSFNRASELSKQKETEKGPSANITLANGNQVSITNLLQYD
NEFIWKANTITIKVSEISEDKRNNNRPHKYLVYAQINDGTENGKPKFRKL
GTLAREQENKLEEIGITLGQEVKSNKILFQPELSEGQIKLLYQKAYQIAE
EFYNSISEDQKLTMAAATWAVSTTRESSNDKSSDRQNKVSNFAFAAFPQE
IVSQLDILKFTEFSITGFDRNSEFFNENQPQSIRFNLAEDGKSVIEIQNQ
EGSYKTFGNIEQSNARLPIGTIAIGSVEKGEVYTTSVTTKVPGLPELTFK
VGEVNKFGNSQRFNNEPVMLTIEKVDLIREDYTIYLQNGNKPEKLGNIDK
ESIKEGIAQGWLAEKPGNGQKLHLKIQTIITGQNAYAIAETSQSNLLRIN
ITNPKYKKQEINNQAFQETLVRAFDKKHVYIAKIGDQSLGIIGQHNERLE
ADLNKGNIQKQWQRKESSTVQKLIDTGIIRQNQQRTTIPVQITSNESTCK
IIINPETVQYPDKWVKRSQLISNEKPVRDEQQEERNQILGKINERPTIMF
QDKEQKLVGLLGLAVDENIAEKTKKYLEKVGVSYEQLPISQARLEAKKGM
TVFVLDETTISSELRQTFINRAGGHIKSADTPSQPTPIIPQQTVYFYNPN
QQYTFPDGAQAETQEAFGLVVPAQDAIAVATWLESKSTENDYFIESNTAT
FIFNKNEISEKITEELNTLLGEAINIGEVDGFDRYEQLSAELNQKVATEG
SLLKLNQIPETSEYQKALQALPNRPRELNQEDSPVPIIPAKALPEKNTTN
IQSNTNATVGGISQVYQNAVEIQVLTDIQAEAKNQPILLPNSRQADPTKA
IEILGKISEKKVEQLRSHLETHFKPILENDKSNYAPLRQVAWVGAKWDLK
DKDFKPGVQDDKLMELVKQVYPDADIVLVTYSENPGAGINYHRDDSYAAT
EARSINIGNSDWGYRAAKERMAWTSEENQDAPYQEFKLESGTVTRFNCKN
EHAALNTEVGRWSINIWSIKNDLGRENSVRQKFENFLTSNQPPRAVVQSN
NNLTIKANEWTPGGEIKVERSYTSLREVAQNIPSHPSNQLTVEEIIAIGN
STAARAANSQIPYNPTISGKPIPMVYSLHLHGEAATIPVDTTIDAMRGHG
RIHTTRGVDYQKTYGINEGDIAIAQGKNGEQVAFRVGKQYKITTQMIQDP
SYQQAWARWEKHSPKELTQTQASKSQVYGLFMEPLGDYVNDKIVPFPTIQ
KQPATPVNISPDSKDGLGVALSLATALAKEQGKLQNDYQVSVNNDPEAPA
GQYGLETHVQKPQGVAYASAEHAFNHQKQLYPSVDEYQLMVEVLQAKLEQ
HPRLTEAIAKRGGVNWLENCTNITNAQDQQWQGKGKESAFIQALSEAYIY
VVAKSQQTTVQTQQDKSQQTALRPTNPLSQLEPINAAVAEHMKKDIAMAQ
IATQFIGKSAAPPGTASSTRNYEQAWGERANTGNYSKEDIIMVSGSGPWR
GVTSKQIAQTFENHYKPLLDKAIAVKSSFLVGNAQGTDQLVQNYLQEKGY
KVEQTSQGYAVFNPVENSKVSSDIISTNTQVLHNSLIAKDKSIFSPQQSQ
QPNIDQALASPAQPKMQQVGAMDSIIERMKANTVQNLQDWYMAAEKLGKS
DTYLNRIQEVTNLYIQENISLENAFKAMEQDIKELEKVNEMTSLAQRVVK
TIGQEDINGIMTVQTEKYQIATQTQNQTYLVKDKKDNILLYVKQGKTQVS
NISDETLQDFQVMSDRINNALKDVKKNLVER
>Ava_4923 Serine/Threonine protein kinase
MSYCINPTCPNPENVAYSQRCEACGSRLLLRDRYRVLKPLGQGGFGATFL
AHDQILPGEPSCVIKQLRPSGTAPHVLQMARELFEREAKTLGTIGNHPQV
PRLLDYFEEQEQFYLVQEYISGSTLQQEVKLNGTLSEAGVKQFLSEILPL
LQYIHEHKVIHRDIKPANLIRRSQDARMVLIDFGAVKNQVSQAITNQSAN
TALTAYAIGTPGFAPPEQMAMRPVYASDIYALGVTCVYLLTGKTPKDLDY
NPTTGEVMWEHLVQVSDHLIGVLRKMLEVSVRSRYQSATDVLKALEIEPY
LESLAQGLLVKSEKEQTSQRPENSAVLSSSSPVAATSVGGVAQVAAAIRA
RRAKDAAAKLAILPNSNSNGNGLPTQQSKAGRRLDSQTLIKAYLKGRRDF
ALHNLNFLNLQGVDLSETNFHSAQLQSTNLQGANLHNSDFGRASLTRANL
KDANLSKAYFNHADLEGADLRGADLSHAYLSNANLRGTNLCGANLTGAKI
TDEQLALAKTNWMTIRPNGKRGLL
>Ava_0402 Protein serine/threonine phosphatases
MLSIERIIYCINKNCDNPINFAGERVCASCQTPLVHRYLWATGSLATEIP
LGTKVSDRYEVIERQVWLDTRPGLLPEVPQELPPDVIPYLRLYPERSHLP
QVYGFVTSSPEGADNTLLLENVPIDEEGNIYPTIIDAWEKAKPVRQVYWL
WQILQLWTPLLELGLAHNLLRADNLRVQGWCVRLLDLNAKTPTEQPNLKD
LSDSWQPLLELTTTSVTSKLQNIIQQMANSEVELETIATQLNALLLAVAG
ELPLTLTIAGATDAGPQLKQNEDTCYPNTAVDSHELLVPNLAIVCDGIGG
HQGGEVASQLAVQSLKLQIRALFTEVAAQPEIVPPTLLQEQLEASLRVAN
NLINSRNDEQKRQGRERMATTLVMAVQVPQRVLTTSEWQSDNGHELYLAN
VGDSRAYWITCEYCQQLTVDDDIVTREVRSARSLYRQALQRQDANALTQA
LGNRDAESLRLAIKRFIIDEDGILLLCSDGLSDNNWVENSWQDYAVPVLT
GQMTVEDAAHHWINLANEKNGHDNTSVVLTLCRVSKEYLVPITPTPPLVE
IPEPEIAELERYPEESILTESSQALLDLELPDEPSPAPIKQPNRRQPLLL
VGGLLALLIGGTGIGLFAWWQLSPQSFQQMCQKLPPSLQQYCSPRGR
>Ava_C0194 Two Component Transcriptional Regulator, LuxR family
MKPINVVIIENENISRVGAATILSETGKIQVCGLAKTGKQGIELVDQQKP
DIVVINIDLPDINGTDVISLIKCKHTSIKIVVMTANSSRDTINAAISNGA
DCYYCKNNAREEVGERFIEAVMAAYNNESWIDPTINRILIDNLRSNDTAD
RDSLDLLSDFSNKEITVLKLAAGGMKNNEIANVMYVSEGTVRSYLHNSFI
KLGVKDRLNAIREAIRLGILSFADMKIEEEVTQATHTRVKTNQNSQKDTA
KTSNKGYKGWVA
>Ava_4135 Periplasmic Sensor Hybrid Histidine Kinase
MRSSAKTIIGYIHKVCFQDWRSIFMTAPVVAICVMTGGMAGLFQLLEWNM
MEQYYALRPVESIDKRILIVTIDEQDITQIGKWPIPDLILAKLIVKLKAQ
KPATIGLDIYRDLPVEPGHQELVGVIKSTPNLIGIKKLVGDQVAPSPTLS
ELGQIALADLVADTDGKVRRGLLSAGDSEEKIFLGLAPRLSLMYLQSKGI
ALEELNPTGTSLRLGKAVFTPLTGEEFSYRGTDVGGYQIMLNYRGFQGNF
DTVKMRDILNDSISSELIRDRIILIGTTAKSINDFVNVGYSHNVQDDEKR
MAGVVVHANLVSQILSAALDGRPLLRVCSEQAEWLLIFFWSFINSVVTWY
GLQVNSQRKQSLPGWPILVILLSTSIIFGSSYTAFMIGWWIPVMSPLLTT
FLSIIVTTNLYKQLQLEKANQQLQDYSRTLEEKVRDRTQELETAKIAADV
ANQAKSEFLASMSHELRTPLNGILGYAQILERSENIAPTVLEGINIIHQC
GSHLLTLINDILDLSKIEAGKLELHNTDFDFSYFLTGVVEMCRIRALQKG
ISFHYLPDPHLPQAINADEKRLRQIIINLLGNAIKFTETGGVNFTIQVLE
VGANFHKIRFQVEDTGVGMTPEQLTKIFLPFEQVGDKSKQVEGTGLGLAI
SCKMAELMGGQIQVDSILGTGSKFWLDLNLNIISHWLQTSSIFHKKKIIG
IQGKQPRILVVDDKWENRSIICNFLRSIGFECLEATNGQEGLNIAVTNQP
DLIITDLAMPVIDGFEMIQTLRSLPQTSNVTILVSSASVFESDRKKSLQI
GGNEFLPKPLEIDKLLQYLQDYLQLDWIYIEDSKQTKVSENQPSQFNKHQ
LIVTPPISALDKLLDLSMRGNIKGIQIILNEIEELDATGNLTGFVTQVRQ
LCDSFQIKQIRELIKYLKTGTS
>Ava_0153 Serine/Threonine protein kinase
MLGQLLDGRYKITQVLGAGGFGKTYIAEDIKLYNNLCVVKQLQPTANDPI
TLQVARRLFASEAELLHKLGTHDQIPQLLAHFEEHQEFFLVQQFIDGHPL
SDELTPGKRLSEAYTIALLKNILQPLAFVHQNNVIHRDIKPPNLIRRKSD
GKVVLIDFGAVKQIGTQVVNGEGVTKMTVSIGTAGYMPSEQSRGSPRLSS
DVYAVGMIGIQALTGLMPHQLQEDIQTAEIIWRELVQVSPNLADVLDRMV
RYDFRQRYQSAVEALAAVQNLGNAYAPTQTSPSPGSKPTLPVKNHVNTPP
VAEPPLYSPPPAVPAQYRQEVPKNLIAPPPPTTAKSSKVGISFYLQWVLV
NIVGLVGGGIVGAIAYEIFEPLGIIISSQAVAATMGLTIGFIQALVLRRQ
IPVSEKQWVLGTTLGVCISVLVCGDYPEYSLLWIGPIVGSIQWFILKPYV
KQAVWWILVNTLFGWIGGIISGAVLVFLLKNLKDF
>Ava_1539 Dual specificity protein phosphatase
MYKFAPACEQETIVFGAARPGYSDQEVYNWIEFMRQQNIKRVCCLLSNEQ
LAGYSHLLSTYQQEFGNQQVCWAAIADFHLADLATLTEKILPFLIEADKL
KERVVVHCSGGIGRTGHVLAAWLVCGRGFANQDAIAAVKCTGRNPHEAVI
AAVFQGKNPLTVAKELDFLLNNCRILT
>Ava_0413 PAS/PAC Sensor Signal Transduction Histidine Kinase
MYNETLKQQINLLQQQNAELKQQLAATTQESSAIIARLEQELSESKNWWL
FFDLSVDILCITDFNGYFQRVNQAGENILGYSQAELLSLPFMELVHPEDR
AATLAEMSKLTEEIRVFRFENRYRCKDGSYCWLSWTSVAHDNYIFAMARD
VTDSVELRLCKQTEAMLRQQEAQYRGIFETVNDGINVFDLDTGEMVAVNP
ALCEMHGYSQTEFLSLRPTDYIHTESYDQFKDFIKTVKSGQKYHTQAVGI
RKDGTSFEIEVTGKLFDYDGRPHAISVVRDISERIQSEQEQQRLLAILEA
TPDIVGIADVYGTNCYLNKAGQRMLGISSTDQFPISEAVGLSIFEKFQTE
IIPLVMQQGIWSGEALMRSRNGEEFPVSQVIIAHKNEQGEVEFLSTIARD
IRDRQQIEARLRQQAQDLEATVQELQRTQTQMIQAEKMSSLGQLVAGVAH
EINNPVNFIHGNLNYLEEHTQDLLRIIEVYQQKNTNYEPGLQDLHEEIDL
EYIQQDLPKILNSMKVGTQRIRQIVLSLRTFSRMDEAEFKAVDIHAGIDS
TLMILQHRLKEQPERPAIQVIKEYGVLPSVECYAGQLNQVFMNILANAID
ALEESVVSGQWSVVNAEVTDKGQQTNDIPTIRISTSVIGSNWIKMAIADN
GMGMSEKTQQQIFNPFFTTKPVGKGTGMGMSISYQIITEKHGGKLLCNSH
LGKGTEFIIEIPIQQ