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# Streptococcus pyogenes phage 6180.4

>M28_Spy1833 phosphohydrolase
MKDLLKQYQAKPLGEEKRYAVFLPLILVNDDWHVLYEVRSQHISQPGEVS
FPGGQVENQETLQEAAIRETVEELTVDASQIQLWGEIDYLVQSSRTIHCF
VGQLVVDDWKSIQPNEEVDKVFIVPLRQLLFTDPVYYRLEATPIETTDFP
FDRIRNGKYYQFSQEYRSIPFYENLEETIWGMTAQFTKCLTDILNDESIA
KKNPSDIENSKGR
>M28_Spy1464 acetyltransferase
MIQQSLVIEEGVPQDAKAVLSLVAAAAKETDFITGVETILEATPHELSDF
LSRSQTSFIDFCLLARLDEKVVGLLNLSGEVLSQGQVEADVFMLVAKTYR
GYGIGQLLLEIALDWAEENPYIESLKLDVQVRNTKAIYLYKKYGFRIESM
RKNDIKSKNGDDLDVYHMRKSVSQ
>M28_Spy0491 hydrolase (HAD superfamily)
MSIKLVAVDIDGTLLTDDRRITDDVFQAVQEAKAQGVHMVIATGRPIAGV
ISLLEQLELNHKGNHVITFNGGLVQDAETGEEIVKELMTYDDYLETEFLS
RKLGVHMHAITKEGIYTANRNIGKYTVHESTLVNMPIFYRTPEEMTNKEI
IKMMMIDEPDLLDAAIKQIPQHFFDKYTIVKSTPFYLEFMPKTVSKGNAI
KHLAKKLGLDMSQTMAIGDAENDRAMLEVVANPVVMENGVPELKKIAKYI
TKSNNDSGVAHAIRKWVLN
>M28_Spy0493 dGTP triphosphohydrolase
MNEKVFRDPVHNYIHIDNPLIYDLINTKEFQRLRRIKQVPTTAFTFHGAE
HSRFSHCLGVYEIARRVTAIFEEKYADIWNKDESLVTMTAALLHDIGHGA
YSHTFEVLFHTDHEAFTQEIITNPETEINAILVRHALDFPDKVASVINHT
YPNKQVVQLISSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVED
GIVFEHSGMHAVEDYIVSRFQMYMQVYFHPASRAVELILQNLLKRAQHLY
PEQQAYFQKTAPGLIPFFEKKANLADYIALDDGVMNTYFQVWMASEDHIL
SDLASRFINRKILKSVTFDQDSRGELERLRQLVESVGFDPDYYTGIHINF
DLPYDIYRPELENPRTQIEMIQKDGSLAELSQLSPIVKALTGTTYGDRRF
YFPKEMLELDDLFAPSKETFMSYISNGHFHFSQ
>M28_Spy0719 tetratricopeptide repeat family protein
MRRLRTMLNSEKMIASLDQQDLAHAEKYFQKALKEDDADSLIALGEYLES
IGFLPHAKRIYLQLADDYPELNINLAQIAAEDDAIEEAFLYLDKVSKDSP
NYLSALLVMADLYDMEGLTEVAREKLLQAVSISPEPLVIFGLAEIDMSLQ
YFKEAIDYYAQLDNRQILELTGISTYQRIGRAYASLGKFEAAIEFLEKAV
AIEYEDETVFELATLLYDQENYQKANLYFKQLETINPDYPGYEYGYALSL
HEEHKTSEALRLVQQGLRKNAFDSQLLLLASQLSYELHDRQNAENYLLQA
KEVAVDDEEILMRLVTLYFDAERFEEVIALNRETIDNVLTKWTIAKAYHA
LEQEEVALALYNEISADLAENPEFLQDYAYLLREFGQFHKAIQMATAYLR
QVPDDVNMQDFLDHIKHQQSE
>M28_Spy0893 ABC transporter ATP-binding protein
MTAFLMTVKEETMSILEVKQLSHGFGDRAIFENVSFRLLKGEHIGLVGAN
GEGKSTFMSIVTGHLQPDEGKVEWSKYVTAGYLDQHTVLESGQTVRDVLR
TAFDELFKTENRINEIYASMADDKADIAVLMEEVGELQDRLESRDFYTLD
AKIDEVARALGVMDFGMESDVTSLSGGQRTKVLLAKLLLEKPDILLLDEP
TNHLDAEHIEWLKRYLQHYENAFVLISHDISFLNDVINIVYHVENQSLVR
YTGDYYQFQAVYEMKQSQLEAAYERQQKEIANLQDFVNRNKARVATRNMA
MSRQKKLDKMDIIELQAEKPKPNFEFKQARTPSRFIFQTKNLVIGYDYPL
TKEPLNITFERNQKIAIVGANGIGKSTLLKSLLGVIEPLEGHIVTGDFLE
VGYFEQEVTGVNRQTPLEVVWDAFPALNQAEVRAALARCGLTSKHIESQI
QVLSGGEQAKVRFCLLMNRENNVLILDEPTNHLDIDAKNELKRALKAYKG
SILMVCHEPDFYNGWVTDTWDFSKLT
>M28_Spy0028 autolysin
MKKFHRFLVSGVILLGFNGLVPTMPSTLISQQENLVHAAVLGDNYPSKWK
KGNGIDSWNMYIRQCTSFAAFRLSSANGFQLPKGYGNACTWGHIAKNQGY
PVNKTPSIGAIAWFDKNAYQSNAAYGHVAWVADIRGDTVTIEEYNYNAGQ
GPERYHKRQIPKSQVSGYIHFKDLSSQTSHSYPRQLKHISQASFDPSGTY
HFTTRLPVKGQTSIDSPDLAYYEAGQSVYYDKVVTAGGYTWLSYLSFSGN
RRYIPIKEPAQSVVQNDNTKPSIKVGDTVTFPGVFRVDQLVNNLIVNKEL
AGGDPTPLNWIDPTPLDETDNQGKVLGDQILRVGEYFTVTGSYKVLKIDQ
PSNGIYVQIGSRGTWVNADKANKL
>M28_Spy1187 pyridoxal-5'-phosphate family protein
MDLLTNKKKIFETIRLSTEAANRTNDSVSVIAVTKYVDSTIAGQLIEAGI
EHIAENRVDKFLEKYDALKYMPVKWHLIGTLQRRKVKEVINYVDYFHALD
SVRLALEINKRADHPVKCFLQVNISKEESKHGFNISEIDEAIEEIGKMEK
IQLVGLMTMAPANASKESIITIFRQANQLRKNLQLKKRKNMPFTELSMGM
SNDYPIAIQEGSTFIRIGRAFFH
>M28_Spy0965 ABC transporter permease protein
MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSDGLFGVL
TNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVN
SHQIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKM
DYFINMLTVLAYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILV
ILISVAATYVHSHIFNINTSADSFPFTEQKTIYLLILEQFIEMIMFYLAT
NFIIKNKLNLQ
>M28_Spy0295 CBS domain containing protein
MIAKEFETFLMSHLDNYLIPEQDLAIFIDTHNADHVMLLLVSNGFSRVPV
ITREKKYVGTISISDIMMYQSKRQLTDWEMSQTDIGEMVNTKIETISITS
SLTEIMHKLIDFPFLPVVDRANRFVGIITRKSILKAVNSLLHDFTDDYTI
IKK
>M28_Spy1774 acetyltransferase
MEIRRPTLKDKDAVLSMINEFLEQKSATDGLWHFNVNDFNYETWLEDSLR
QEMGLSSQGVPAIQYVAFDERSQAIGFLNLRLRLNERLLEKGGHIGYSVR
PSQRGKGYAKEMLKQAVSYAISKNITTILVTCDETNVASRAVIVANGGVL
EDSRGGTERYWIEEQRGDK
>M28_Spy0348 short chain dehydrogenase
MTKVVLVTGCASGIGYAQARYFLRQGYHVYGVDKSDKPDLSGNFHFIKLD
LSSELSPLFKVVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINFFAT
VKLTRHYLRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQ
LALDYAKDQIHIFGIAPGAVKTAMTASDFEPGGLAEWVARETPIGRWTEP
DEVAELTGFLASGKARSMQGEIVKIDGGWTLK
>M28_Spy0467 hypothetical protein
MDLVGISLMIIALAFVALVIFLIIVLKKVSETIDEAKKTISVLTSDVNVT
LHQTNDILAKANILVEDVNGKVATIDPLFVAIADLSESLSDLNSQARHFG
QKATNATGNVSKAGKLALVGKVASKVFGKKGEKHE
>M28_Spy1771 glyoxalase family protein
MTYPYNSTISLGTVSLNVTDLAKMTTFYTSIIGLQVLSQDTTSRQLTTDG
KTVILELRQTPLPANKAYGLYHTSFLVPDRHSLGLVLNHFLTRGISLEGS
ADHGYSEAIYLSGPEGNGIEIYHDKAVEHWDIRDNGQIIGVTEPTDTKSI
LEQLTDIPKRFLLAQDTRIGHVHLSVKNALASSLLYQKVFDLGDKMTIPS
ASWIASGNYHHHLAFNHWSAPYLKKHQEGAPGLAFLTIHIETPLLFSATL
KKARLHGLAILQEDSSSFTTEDEEGICVNVILGQD
>M28_Spy1254 hypothetical ABC transporter ATP-binding protein
MPSFNIVKKNDLNSSFKVSKVMADFDVGAEHVREHFIGKIDYPDKWQIGL
IVGGSGTGKSTIAKELYNEALEDDFVYPDKPVIDCIPCHNVEELQKMFYA
VGFGSVPSWLKPYHVLSNGEKMRVDLARRILTKEFIVFDEFTSVVDRQVA
KIICIALKKALKRYPDKKFIAVGCHHDVIEFLQPDWCFNTDDMQQVFRFP
HEANKNSQSEDAQLPSGENLDVIII
>M28_Spy0856 GTP-binding protein
MATIQWFPGHMSKARRQVQENVKHVDFVTILVDARLPLSSQNPMLTKIVG
DKPKLMILNKADLADATRTKEWKAYYESQGIKTLAINSKEQSTVKKVTEA
AKELMADKIQRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIAVVG
NKPGVTKGQQWLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQL
LPMDEVTIFGLNYFKTHYPSRLTKRFKNIPLEEEAPEIIMTLTRQLGFKD
DYDRFYTLFVKEVRDGKLGQYTLDQVGDMDVD
>M28_Spy0913 nucleoside transport ATP-binding protein
MKGNDPMTQHVIEMREITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
STLMNMLAGLLEPTSGEIVINDKPVQIDSPSKSAKLGIGMVHQHFMLVEA
FTVAENIILGNEVVKNGCLDLNQASKDIKVLSEKYGLAINPSAKVSDISV
GAQQRVEILKTLYRGADILIFDEPTAVLTPAEIKELMTIMKNLVKEGKSI
ILITHKLDEIRAVAERVTVIRRGKSIETVDVAGATSQDLAEMMVGRSVSF
TTSKKAAEPKDVVLSIKNLEVDENRGIPAVKGLSLDVRAGEIVGIAGIDG
NGQSELIQAITGLRKVKSGSIMIKNKEVTHLSSRKITELSVGHVPEDRHR
DGLILDLSLAENTALQTYYKQPLSQNGILNYTKINDYARQLMKEFDVRGA
NELVPARGFSGGNQQKAIIAREVDRDPDLLIVSQPTRGLDVGAIEYIHKR
LIKERDKGKAVLVVSFELDEILNLSDRIAVVHDGKIQGIVLPENTNKQEL
GILMAGGSIHKEEGHV
>M28_Spy1658 oxidoreductase
MKHILFIVGSLREGSFNHQLAAQAQKALEHQAVVSYLNWKDVPVLNQDIE
ANVPLPVVDARQAVQSADAIWIFTPVYNFSIPGSVKNLLDWLSRALDLSD
PTGPSAIGGKVVTVSSVANGGHDQVFDQFKALLPFIRTSVAGEFTKATVN
PDAWGTGRLEISKETKANLLSQAEALLAAI
>M28_Spy1467 hydrolase (HAD superfamily)
MTKKLIAIDLDGTLLHHDNTISTYTQKIIKAVQDKGHHVIISTGRPYRMA
LDYYLQLNLKTPIITFNGALTHMPEQKWAYEHNVTLDKGYLLRLLKYQDD
FQMDFIASEYRKNVYITMTNPESIDPQLFGVDEITQDMALEITKITRNPN
ALLMQTHHEDKYALAKNMRAFFKDEIEIDSWGGPLNILEISSKNVNKAYA
LNYLLGIYNMDKKDLIAFGDEHNDTEMLAFAGTGYAMKNASPVLLPYADQ
QLNFSNEEDGVAKKLEELFL
>M28_Spy1131 putative competence protein/transcription factor
MTKILTALDGKNQLISLVTQPISTKPPFCCPACKSPVRLRQGTIRRPHFA
HVQLAHCQFQAENESEEHLTLKAKLYTSLVRTEAVCIEKYLPELQQIADL
WVNDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTA
LQKQFLYFSSSLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLD
HNIMEMFRLPYQQEILYSYQKKMTVNLSKRIQRALLARHPKWLRRQEKAY
LSGYNLLMLTTDAFYPQWRPVQSSSGFCQIKGNLRPYYESFKVYYKKEKD
KKVQTLFSPKYYVKMDSNRK
>M28_Spy0323 corrin/porphyrin methyltransferase
MQVQKSFKDKKTSGTLYLVPTPIGNLQDMTFRAVATLKEVDFICAEDTRN
TGLLLKHFDIATKQISFHEHNAYEKIPDLIDLLISGRSLAQVSDAGMPSI
SDPGHDLVKAAIDSDIAVVALPGASAGITALIASGLAPQPHVFYGFLPRK
AGQQKAFFEDKHHYPETQMFYESPYRIKDTLTNMLACYGDRQVVLVRELT
KLFEEYQRGSISEILSYLEETPLKGECLLIVAGAQVDSEVELTADVDLVS
LVQKEIQAGAKPNQAIKTIAKAYQVNRQELYQQFHDL
>M28_Spy1639 hypothetical cytosolic protein
MKKRILLVDGYNMIAFWQSTRQLFKINQLDQARNTLLTKLNHYAHFENIN
IICVFDAQYVPGLRQRYDQYYISVVFTEEDETADSYIERMAAELNTAIHM
VEVATSDLNEQWTIFSQGALRVTARELEQRVHTVKADLDKMSRDIDLKTP
KLRPFDQGQLIQLKDFMSQLDR
>M28_Spy1430 aldo/keto reductase family
MMVTTVKMTSGYEIPVLGFGTYQAADGEEAYQSTLAAIKAGYRHIDTAAI
YKNEESVGRAIKDSGVLREDLFITTKLWNDAHSYEGAKDALAASLDRLGL
DYVDLYLIHWPNPKALRNTWKEANAQAWQYMEEAVEAGLIKSIGVSNFMV
HHLEALQETAKITPAINQIRLAPGCYQKEVVDYCKANEILLEAWSPLGQG
EIFDNETMQQLANKYDKTVAQVALAWSLAEGFIPLPKSVHDERIKENMAI
FDVSLTQEDKKTIRYLSGMSAIPNPDTTSF
>M28_Spy0252 putative lipase
MLFQKKYDKIESTNYFGDDMSIDDYRPTYMVEAIYDLRANDLLRHGITAV
LVDLDNTLIAWNNPDGTPEVRAWLDEMTIADISVVVVSNNKHSRVERAVS
RFGVDFISRALKPFAYGIEKAIARYGFDRNEVIMVGDQLMTDIRASHRAG
IKSVLVKPLVASDAWNTKINRWRERRVMAKLEEKYGKLSYQKGI
>M28_Spy0284 aminodeoxychorismate lyase family
MALTDFKDKDQQDQQRSFKEQILAELEKANQIRKEKEEELFQKELEAKEA
ARRTAQLYAEYKRQDAFQKESIAHNNKTAKHFQAIKGAVMTSEALKPTLL
SEKENSSLKTTNKRVVQANELQETASKESQVPLTIEKGHSVRRKLSKRQQ
TERAAKKISTVLISSIIITLLAVTLAGAGYVYSALNPVDKNSDAFVQVEI
PSGSGNKLIGQILQKKGLIKNSTVFSFYTKFKNFTNFQSGYYNLQKSMSL
EEIASALQEGGTAEPTKPSLGKILIPEGYTIKQIAKAVEHNSKGKTKKAK
TPFNEKDFLDLVTDEAFIQDMVKRYPKLLATIPTKEKAIYRLEGYLFPAT
YNYYKETTMRELVEDMLAAMDATLVPYYDKIAASGKTVNEVLTLASLVEK
EGSTDDDRRQIASVFYNRLNSGMALQSNIAILYAMGKLGEKTTLAEDATI
DTTINSPYNIYTNTGLMPGPVASSGVSAIEATLNPASTDYLYFVANVHTG
EVYYAKTFEEHSANVEKYVNSQIQ
>M28_Spy0717 mutator protein T
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECA
RREILEETHLTVTEMAFKGIITFPEFTPGHDWYTYVFKVTGFEGDLISDE
ESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQL
MDKSVTFY
>M28_Spy0993 phage protein
MNRESKPGMESVKIGGLTYSVEKASDLQGKDGNWGLIHYKTQQIKLDDSL
TEQLEDQTLIHEIVHGILVEAGYTNHEEDQANRIGLILYQVLQDNDFSWL
YKGE
>M28_Spy1598 alpha/beta hydrolase
MKTIRIAKYLGILFLLITLISVGASFYFFHVAQIREEKSFINNKKRSTNN
PLYPAEQSFDALPYEKRQLTNRGLKQVGWYLPAAQKTKKTAIVVHGFTND
KEDMKPYAMLFHDLGYNVLMPDNEAHGESEGNLIGYGWNDRLNVMAWTDQ
LIKENPESQITLFGLSMGAATVMMASGERLPAQVTSLIEDCGYTSVWDEL
KFQAKAMYNLPAFPLLYEVSALSKIRAGFSYGEASSVKQLAKNKRPTLFI
HGDKDDFVPTKMVYDNYKATKGPKEILIVKGAKHAKSFETNPEQYQKKIA
AFLKKVEK
>M28_Spy0738 hypothetical membrane associated protein
MTYTSLKSPENTDYLYDLNIAHLYGNLMNTYGDNGNVLMLKYVAEKLGAR
VTVDIVSINDTFEQDDYDIVFFGGGQDYEQSIVAKDLPSKKAALADYIAN
NKVVLAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKI
HNDEFNETYYGFENHQGRTFLSGDEKPLGRVVYGNGNNKEDQTEGVHYKN
VYGSYFHGPILSRNVNLAYRLVTTSLKKKYGSAISLPSYDDILKQEITEE
YADLKSKASFNKV
>M28_Spy1812 phage protein
MSKKNAIRKLKEFHRWQRIANSLDLTYTELYQFDIEYHPTRRKHLEISRE
CALEELDAIRYAINQLSKVEYRQILIECYLISEEKTQQDIMEELNRSQSW
YYESKKRALLEFVEFYRDGALKNNVRL
>M28_Spy0711 para-aminobenzoate synthase component I
MDSQLSNRLAQVAAYVPKGVKLLDVGSDHAYLPIFLVETNQISAAIAGEV
VRGPYESALKNVTQSGLAEHIQVRLANGLAAFEEADDVTAITICGMGGRL
ITDILEAGKEKLQGIERLVLQPNNREDDLRAWLSVNAFKIVAETIMAEND
KYYEIIVAEHGEKALSATELRFGPYLSQEKSVVFKEKWQREMDKLAYALS
CIPEEKTQERQLLLTKIQQIKEVIVHES
>M28_Spy0417 putative transmembrane protein
MRILFVVSTERSFKMWSFWKRYRPFLSAGIQELITYRVNFFLYRIGDVMG
AFVAYYLWKAVFDSSKQSLINGFTLSDMTFYIIMSFVTTLLTKSDSSFMI
GEEVKDGSIIMRLLRPVHFAASYLFMEIGFRWIVLMSVGFPFLMVLSGIK
VMAGLSTLQVLASSCLYLVSLLLAFLINFYFNICFGFSAFVFKNLWGSNL
LKNALVAFMSGSLIPLAFFPKVVYIVLSFLPFSSLVYTPVMIVIGKYSLS
QIMVALSLQIFWLLVMVVLSQVIWKKVQYHLTIQGG
>M28_Spy0580 hypothetical cytosolic protein
MSDTPKYTQDQVIAIKNRILEALETVIDPELGIDVVNLGLIYEIRFNDNG
YTEIDMTLTTMGCPLADLLTDYIHDALQDVPEVTKTEVKLVWYPAWTVDK
MSRYARIALGIR
>M28_Spy0349 NAD-dependent oxidoreductase
MMSQTVKGDEQMKLAVLGTGMIVKEVLPVLQKIDGIDLVAILSTVRSLKT
AKDLAKAYHMPLATSEYEAVLGNEEIDTVYIGLPNHLHFAYAKEALLAGK
HVICEKPFTMTAGELDELVVIAKKRKLILLEAITNQYLNNMTFIKEHLDQ
LGDIKIVECNYSQYSSRYDVFKRGDIAPAFNPKMGGGALRDLNIYNIHFV
VGLFGRPKTVQYLANVEKGIDTSGMLVMDYEQFKVVCIGAKDCTAEIKTT
IQGNKGSLAVLGATNTLPQVQLSLHGHEAQVVNHNKYDHRMYEEFVAFRD
MIDQRDFEKVNQALEHSRAVMAVLERAVHS
>M28_Spy0416 putative ABC transporter
MVMIEVSHLQKNFSKTIKEPGLKGALKSFVHPQREIFEAVKDLSFEVPKG
QILGFIGANGAGKSTTIKMLTGILKPTSGYCRINGKIPQDNRQDYVRDIG
AVFGQRTQLWWDLALQETYVVLKEIYDVPEKAFRKRMDFLNEVLDLNEFI
KDPVRTLSLGQRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAIT
QINQEEKTTILLTTHDLSDIEQLCDRIIMIDKGQEIFDGTVTQLKQSFGK
MKSLSFELKPGQEQVVSQFMGLPDITVERHELSLDIQYDSSRYQTADIIQ
KTMADFAVRDLKMTDVDIEDIVRRFYRKEL
>M28_Spy0480 integral membrane protein
MSAKFMSRIAIMSALCVVLRMVFSSLPNVQPVTAFLLSYLLYFGLAEAVL
VMMLCLFLSAFLLGFGPWVFWQVTCFVLVLLLWRFALYPLSQQFPKYQLG
YQAFLAALCGLLYGVLIDTCFAYLYSMPWWSYVLAGMPFNIAHALSTLVF
FPVVMMLFRRLIGEQKI
>M28_Spy0531 DNA gyrase related protein
MKGMNYQDYIWDLGGTLLDNYELSTQAFVQTLAFFSLPGDHDAVYQKLKE
STAIAVAMFAPNEPEFLHVYRLREADKLAQPIWCLGAKEILEKIATSGSR
NFLISHRDCQVNQLLEQAGLLIYFTEVVTASNGFARKPNPESLFYLKEKY
DINSGLVIGDRLIDKQAGQAAGFNTLLVDGRKNLLEIVT
>M28_Spy1295 ATP-dependent RNA helicase
MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFLIGLYHD
LGKADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMT
FNEMVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDI
KGYALKLEKKLCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWDYYQS
CMVRLYLSLLKNADILDTVNAYGLKISPMDKTERSFLKHSYLAAIEQKYA
SFGQPNNQLNTIRTEIAERVKERGKRDSKGIYRLDLPTGAGKTNLSMRYA
FHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTGDLGVLEHHSNVVKQAN
EDDDDKDSLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANLRRFSSLIN
SVVILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIVLCTATQPAYDSSEID
HRICYGGNLGELAEIVELTIEEKQIFSRTELRKFDDSDQKVHLTDVINLI
LGEENSVLAIFNTKKTVHNCYTMLKDITDRPVYQLSTNMCAQHRLDLIAK
IKTELQNNIPIICISTQLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNRE
GKRDKGQVTLVNLTNEEENISRLTEIKAKKEATESILHKIGSPIDISTLN
RDFFEYYYANNQGLMDYPLEDNLSIYDYLSLNIYQTANKKFKGKLKQAFK
TAGAKMNLINNDMIGILVPYGEAEKKLAYLEELGMSHFLSAEDYQTIKSL
LKELQPFTVNVRENDPLFETTKSYLNGQILVLTSEYYDTERGVKYDSASF
YF
>M28_Spy0161 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase
MKKYLNQNVYDALIERLHFLFNEFPIVYISFSGGKDSGLLLNILLDFRDK
YYPDREIGVFHQDFEAQYSLTTKYVQETFTSLEGRKKVSLYWVCLPMATR
TALSSYEMFWYPWDDKTEDIWVRPMPSQDYVINLENNSITTYRYKMNQED
LAKQFGRWYKQIHGNQKTVCILGNRASESLHRYSGFINKKYGYQKECWIT
KQFKDVWTASPLYDWSVEDIWHAYYKFSYSYNELYDLFYKAGLKPSQMRV
ASPFQDYAVDSLNLYRIIDQETWVKLLGRVQGVNFSNIYGRTKAMGYKSI
ALPKGHSWKSYTQFLLSTLPVRLRNNYVRKFNKSIDFWHKTGGGLAEETI
NELIEKGYRIARNGISNYTSFKHSRVIFLDQIPDDTDDIVTTKDIPSWKR
MCFCILKNDHICRTMGFGLTREQQKIVAFLKEKYKTSLKELESE
>M28_Spy1677 exodeoxyribonuclease III
MSYKGGLMTKVLTLNTHSWMQANTLKKLVALAEHILAEKYDIICLQEINQ
LIESELATDLPRYQALSGTPNIHKDHFALLLIHYLQKRGQHYYWSWAYNH
IGYDIYQEGVAILSKQPIHVSDILVSAMADETDYHTRRSLIAKTTLDGKE
VAVVNVHLSWFDKGFLGEWEKLEKELLTLNCPLLLMGDFNNPTDQDGYQV
MMGSPLDLQDSHKVADHVFGDHSIVADIDGWQGNKEALKVDHVFTSKDFI
IRSSKITFEGGDAPVVSDHYGLEVTLGWR
>M28_Spy0722 ABC transporter substrate-binding protein
MKNKSLIATLLVLTVIVIGSLLSKGVSKENRDLANRQNITIGILQFVTHE
ALDDIKRGIEDQLKKQMPQKQNVVIKVMNAEGDQSKIQTMSRQLVQSGSD
IVIGIATPAAQGLAAASKDIPVVMSAVSDPVGSRLVMQLDQPEANVTGLS
NKVPVKQTIDLMKNLTPHVKTVGILYASNEDNSLSQVKEFRRLARKKGYQ
VISYAVPSTNEVPATMSVMLGKVDAVFIPQDNTIASAFSSVMTTSKAAKI
PVYTSVDRMVEKGGLAAISQNQYDLGVQTANQVLKLIKGKRVVDVPVKVV
DIGQPLINKNVAAELGIAINREDFPSASFIEN
>M28_Spy0512 hydroxyacylglutathione hydrolase
MPFIFRHSFFNKALIFWYTILMKIYKTINHIAGENTYYLVNDQAVILIDP
GSNGQEIIAKIKSFEKPLVAILLTHTHYDHIFSLDLVRDAFDHPPVYVSE
KEAAWLSSPDDNLSGLGRHDDIITVIARPAENFFKLKQPYQLNGFEFTVL
PTPGHSWGGVSFVFHSDELVVTGDALFRETIGRTDLPTSNFEDLITGIRQ
ELFTLPNHYRVYPGHGPSTTICHEKNANPFFH
>M28_Spy0862 regulatory protein
MIGQGIASLLGLQPILMSLLIAMIFCFLIVSPITTVGIALAINLSGIGSG
AASFGLCLAGWAVNSKGTSLAHVLRSPKISMANVLSKPKIMLPMLCSAAV
LGVIGAIFNIQGTPASAGFGISGLIGPINALNLAKGGWSPVNILLIIIIF
VGAPIVLNMIFNYLFIKVLKVIDPMDYKLNI
>M28_Spy1372 peptidyl-prolyl cis-trans isomerase
MEESMDAKLKYKAKKIKMVFFDIDDTLRVKDTGYMPESIQRVFKALKAKG
ILVGIASGRARYGVPQEVQDLHADYCVKLNGAYVKDDAKTIIFQAPIPAD
VVVAYKKWADDMGIFYGMAGRHEAVLSARNDMISNAIDNVYAQLEVCPDY
NEYHDVYQMWTFEDKGDGLQLPAELAEHLRLVRWHDNSSDVVLKGTSKAL
GVSKVVDHLGLKPENILVFGDELNDLELFDYAGISIAMGVSHPLLQEKAD
FITKKVKEDGILYALEELGLIDKELQFPQLDLPNHKGPKATIKTNHGDMT
LVLFPDHAPKTVANFLGLAKEGYYDGIIFHRIIPEFMIQGGDPTGTGMGG
QSIYGESFEDEFSDELYNLRGALSMANAGPNTNGSQFFIVQNSKIPYAKK
ELERGGWPAPIAASYAAIGGTPHLDRRHTVFGQLVDETSFQVLDLIAGVE
TGAQDKPKEDVIIETIEVFD
>M28_Spy0175 BioY
MFTTKELVKVAMMTTLIIILGFIPAIPLGFIPVPIVLQNLGVMLAGLMLG
GKKGTLSVFLFLVIGLFLPVFSGSRTTIPVLMGPSAGYVIAYLLVPIVFS
LLYRNWFSKSTPLAFLALLISGVVLVDVLGAIWLAAYTGMSLVTSLLSNL
VFIPGDTIKAIIATIIAVKYKDSFLNTK
>M28_Spy0468 hypothetical exported protein
MEKKEKSMNKSFKNLVIGAVSGVAAAYFLSTEKGKALKNRAEKAYQAYKE
SPDDYHQFAKEKGSEYSHLARDTFYDVKDKLASGDLTKEDMLDLLKDKTT
AFVQKTKETLAEVEAKEKQDDVIIDLNEEDIIIDYTEQDEPVSDTLDKH
>M28_Spy0459 hypothetical membrane spanning protein
MSLFSNLPPSVLQWFAIFMSIIIEALPFVLLGTILSGCIEVFVTPELVQK
YLPKQKCLRILFGTFVGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLAT
APIINPIVLFATYSAFGNSLRFLILRLVGAALVAITLGVMLAFIVDDNIL
KDNAQPVHFHDYSHESLPKRIYLALVHAIDEFFDTGRYLVFGTLIASAMQ
IYVPTRVLTTIGHNPLTAILIMMLMAFILSLCSEADAFIGASLLSTFGVA
PVLAFLLIGPMVDIKNLMMMVKTFKGRFIVQFIGVSVLMIAVYCLLVGVL
>M28_Spy0399 multidrug resistance protein B
MNWRQNLKVAWLGNFFTGASFSLVMPFMALYVENLGTPKELVEYYAGLAV
AVTALASALFAPVWGKLADRYGRKPMMLRASFVMTFTMGGLAIIPNVFWL
LILRLLTGVFAGYVPNATALIASQAPKEESGYALGTLATGVTAGALIGPL
LGGILAELLGIRQVFLLVGVILFLCSLMTAVYVKEEFKPIRRFEMIPTKV
ILKQVKSPQIMLGLFVTSMIIQISAQSVAPILSLYIRHLGQTHNLMFTSG
LVVSAMGFSSLFSSSYLGKLGDRFGNHRLLLAALCYSFIMYFSSALAQTS
FQLGVLRFAYGFGVGALMPSINSLLTKLTPKEGISRVFAYNQMFSNLGQV
IGPFIGSNVAVVLGYRSVFYVTSLIVFVNLIWSLIIFRKYIKVKDIV
>M28_Spy1584 ribosomal-protein-alanine acetyltransferase
MIVTTLSESNMKTVEEQAKNIYQLLEMVYGTSPWTLEQVLIDIRRDQTDY
FLLYDHDKLLGFLAIQDLAGEVEMTQIAILPSHQGLGLASQLMTHLDSIE
SDIFLEVRESNHRAQGLYQKFGFKFIGKRPDYYRNPIETALLMKREGKHD
R
>M28_Spy1157 transcriptional regulator, biotin repressor family
MKAEDRRQKIIECLNSEQKAVSATRLGKLLGVSRQVIVGDIALLRAQQID
IISTPKGYIMSTALYSHQFCARIVCQHNVEETKKELEIILAHQGIITTVE
VEHPIYGMITAPLNIKTHSDVTNFMSKLSQSKAELLSSLTEGLHSHLISC
PSQEAFLAIKHDLELAGILYKGI
>M28_Spy0418 ABC transporter permease protein
MAKLRRMHAIFIKQYLKQIMEYKVDFVVGVLGVFLTQGLNLLFLSVLFQH
IPSLEGWTFEQIAFIYGFSLIPKGIDHLFFDNLWALGQRLVRKGEFDKYL
TRPISPLFHVLVETFQVDALGELLVGVILLVTTAGSIVWTLPKVLLFILV
IPFATLIYTSLKIATASISFWTKQSGAVIYIFYMFNDFSKYPMSIYHSFL
RWLISFVIPFAFTAYYPASYFLTGQHLLFNIGGLVVVSLLVLALSLKLWK
WGLDAYESAGS
>M28_Spy0203 Jag protein
MVLFTGKTVEEAIETGLQELGLSRLKAHIKVISKEKKGFLGFGKKPAQVD
IEGISDKTVYKADKKATRGVPEDINQKNAPAVNSADVEPEEIKATQKLEA
EDTKVVPLMSEDSPAQTLSNLAETVTETKAQQPSIPVEESEVPQDPGNDG
FSKDIEKAAQEVSDYVTKIIYEMDIEATVETSNNRRQINLQIETPEAGRV
IGYHGKVLKSLQLLAQNFLHDRYSKNFSVSLNVHDYVEHRTETLIDFTQK
VAKRVLESGQDYTMDPMSNSERKIVHKTVSSIEGVDSYSEGNDPNRYVVV
SLQR
>M28_Spy0902 ATPase associated with chromosome architecture/replication
MPSSFDLLGEMIDLLQTEQLTSSWACPLPNALTKRQDLWRALINQRPALP
LSKDYLNLEDAYLDDWRASFVPVSVKDCQKTNYTSLFLYHGDIRYLAVDA
IVNAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIG
QAKLTSAYHLPASYIIHTVGPRITKGRHVSPIRADLLARCYRSSLDLAVK
AGLTSLAFCSISTGEFGFPKKEAAQIAIKTVLKWQAEHPESKTLTIIFNT
FTSEDKALYDTYLQKENNCE
>M28_Spy0853 hypothetical protein
MKTVRIFYNPNSGKKENQLARQVKDYFCQHGFSEDSVEVITPKDADQAFQ
LAKQAAKDKIDLVIPLGGDGTLNKIIGGIYEGGAHCLIGLVPSGTVNNFA
KAMHIPLQITEALDTILTGQIMQVDICKANQQYMISSLTLGLLADIAADV
TAEEKRRFGPLAFLKDSIRILKRNRSYAISLISHNHRIHLKTKFLLITMT
NTIAGFPSFSPGAQADDGYFQVYTMKKVSFFKFLWHINDFKQGEFSKAEE
ISHFQANTLSLLPQAKKQAILPRTRIDGDKSDYLPIQLDIIPKAISIIVP
TED
>M28_Spy0726 Zn-dependent hydrolase
MTDIKMIALGGVREYGKNFYLVEINDSMFILDAGLKYPENEQLGVDLVIP
NLDYVIENKGKVQGIFLSHGHADAIGALPYLLAEVSAPVFGSELTIELAK
LFVKSNNSTKKFNNFHVVDSDTEIEFKDGLVSFFRTTHSIPESMGIVIGT
DKGNIVYTGDFKFDQAAREGYQTDLLRLAEIGKEGVLALLSDSVNATSND
QIASESEVGEEMDSVISDADGRVIVAAVASNLVRIQQVFDSATAHGRRVV
LTGTDAENIVRTALRLEKLMITDERLLIKPKDMSKFEDHELIILEAGRMG
EPINSLQKMAAGRHRYVQIKEGDLVYIVTTPSTAKEAMVARVENLIYKAG
GSVKLITQNLRVSGHANGRDLQLLMNLLKPQYLFPVQGEYRDLAAHAKLA
EEVGIFPENIHILKRGDIMVLNDEGFLHEGGVPASDVMIDGNAIGDVGNI
VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSHDILRE
SAELVNTTVGNYLKKDTFDWGELKGNVRDDLSKFLFEQTKRRPAILPVVM
EVR
>M28_Spy0672 GTP-binding protein
MAEEQVLNTHNASILLSAANKSHYPKDDLPEIALAGRSNVGKSSFINTIL
GRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGK
MIEEYLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKA
DKIPRGKWNKHESVVKKALNFDNSDTFIVFSSVERIGIDDSWDAILEQV
>M28_Spy1238 phage protein
MSGIVVDLKRTGFPVKIGQVELWFDTSQERLIEFFDIETEVNRRLNEYEK
QVIEANLDNEIEGKGVTKDVAQSALDLEAKYLEINYDLLFGEGTFAQLYA
EYPDKEALENTLEIVCREIEVKLKELAIEREKIVKQKTKKYKKE
>M28_Spy0572 neutral zinc metallopeptidase family
MKTDDLRESQQVEDRRGQSSGSFGGGGLGGGLLLQLLFSRGGWKTKLVIL
LLLLVMGGGGLSSVLGGKPSSTNNNAYQSSQVTRTNGDKASQEQVSFVSK
VFASTEDYWTKTFREKGLTYHKPTLVLYTGATQTACGRGQASSGPFYCPG
DQKVYLDISFYNELSTKYGAKGDFAMAYVIAHEVGHHIQNELGIMDNYAS
ARQGKSKAKANQLNVKLELQADYYAGAWANYVQGQGLLEKGDIEEAMAAA
HAVGDDTLQEETYGRTVPDSFTHGTSKQRQRWFDRGYQYGDFEHGDTFSI
PYSKL
>M28_Spy0911 nucleoside transport system permease protein
MVNKMSLVTIFALLVSSMLIYATPLIFTSIGGTFSERSGVVNVGLEGIMV
MGAFSGIVFNLEFAETFGKATPWIAVLVGGIVGLIFSLIHAVATINFRAD
HIVSGTVLNLLAPSFAVFLVKAMYGKGQTDNIQQSFGKFDFPGLSQIPVI
GDIFFKNTSLIGYFAIAFSFFAWFLLYKTRFGLRLRSVGEHPQAADTLGI
NVYLMKYYGVMISGFLGGIGGAVYAQSISVNFAVTTILGPGFIALAAMIF
GKWNPVGAMLSSLFFGLSQSLAVIGAQLPLLEKIPTVYLQIAPYMVTIII
LAAFFGQAVAPKADGINYIKSK
>M28_Spy1881 metalloprotease
MTKLVKINYPNIDEDLYYVKLENGLTVYFIKKIGFLEKTAMLTVGFGSLD
NKLTVDDESRDAPAGIAHFLEHKLFEDESGGDISLKFTQLGAETNAFTTF
NQTSFFFSTASKFQENLELLQYFVLSANITDESVSREKKIIGQEIDMYQD
DADYRAYSGILQNLFPKTSLANDIAGSKASIQKITKILLETHHTYFYQPT
NMSLFIVGDIDIDETFLAIQRFQTTLSYPDRKRVTVDPLHYYPVIKSSSV
DMDVTIAKLVVGFRGYLTLTQHSLLTYRIALKLFLSMLIGWTSKIYHTLY
EDGKIDDSFDVDVEIHHHFQFVLISLDTPEPIAMSNYIRQKLATIKISKE
FTNEHLNLLKKEMYGDFIQSLDSIEHLTHQFSLYLSDSDKETYFDIPKII
ERLTLKDVVTIGKAFFEKADASDFTVFPK
>M28_Spy1479 3-oxoacyl-[acyl-carrier protein] reductase
MEIKGKNIFITGSTRGIGLAMAHQFASLGANIVLNGRSAISEELVASFTD
YGVTVVTISGDVSEASEAKRMVNEAIESLGSIDVLVNNAGITNDKLMLKM
TEEDFERVLKINLTGAFNMTQSVLKPMIKARQGAIINVSSVVGLTGNIGQ
ANYAASKAGMIGFTKSVAREVAARNICVNAIAPGFIESDMTGVLPEKMQE
QILSQIPMKRIGKAQEVAHLASFLVEQDYITGQVIAIDGGMTMQ
>M28_Spy1763 transcriptional regulator, LuxR family
MTKGIRFQLLGSPHIFLDDKEQFFAFAKANALLYYLVVNGSVSREVAASL
LWENKNTQTAKKNLRNAIYQVNKVLQADVIICPNRNLLVLKKTLDIKTDI
NLFLADPLAHLELYQGEFLQGFYLKSGEEFDLWVSKMRMQYEQVYLKACY
QKIEEKLSLDAIEDVEEHLKQLIERDEFEEKNYQLLMRLYQQGNCPGKVI
ETYYQLANVLDKELGIQPSLQSQQIYQEVVAKDRNERKIKHFLRNSNHFL
GRIDEIKQLENYFANCLACQEVGALLLIGDTGIGKRTLARQVLANQTQTF
QIVTAKCFREEAMDSLLPWRNILDGLGDLVIQNRLLTTKAWKAALKRCFP
VATIFQEDNNQPFIKDHTSLLVSFIVDILQHLAEIKALVILIEDCHWMDE
DSLTLLQRVMNQLVHYPIAFVLTKHLGTTPELGLCLNALMSQGRLESICL
EPFNRQESLAYINSQLGSQPVTEEEMEHLYQASQGNPFFLSEYTQTLLRH
EKFVPLTPAIKAKLGLKLANLSSRDDALLNYLSCCRRPIPLNTLAQLMLL
PLEEVIEMVDNLGHYYILVEESVGEEVLISFRQRIIQLYSYDRLSLSKRR
LLHGQIAKRLEDLLPILTPSPHLLDDIAYHYQESRQVIKALEYNLNYLDA
TLPFQHELFPIYSKSIGSLEKSDRDHQRLMEEQFDRIRQSIADLELTYDN
NRDFQQLLIRFSYLEGRYDIRTGRYQEGIKNIQKVIALATELKQPSFLLE
GYRQLIHYCIQVENKPEMRYYTSLSLEAAVAANHFEAIAISLRLNGLYHL
IIGELNEAERLLQQSIDFFKVTPGLQANYAIQIAAALDYLGEIAQIRYQF
EKAVAYQKQAIALTENKPAELSVSIFYIGLGISYFYLADFEQAEQILSLA
KEALVNHSYPWKETQLQIYLAMIQWKKGNYQPALTLLDYRETLMSRYRNP
RDKGLVFYLMAVVKYQLIFQGATLSQQEKEMADYLLSESFEYYYEIASTN
LNPYRDCHLVSELNDLRQQLSAKS
>M28_Spy0186 integral membrane protein
MTRLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGAQAIYQVGGMFGLLV
KAMPDQLWRLVTPIFIHIGFGHFFVNGLTLYFVGQIVEDLWGSRRFLLLY
VLSGVMGNAFTFWLSPETVAAGASTSLFGLFAAIVVLSFLGKNQALKDLG
KSYQTLIVVNLLMNLFMPNVSMAGHIGGVVGGVLLSIVFPTKMRVITVKK
TKRMLALVSYGIILVGVLVLGFL
>M28_Spy1212 acetyltransferase
MTDKFDANDETRTVYAVVYDNDQPVSTGQFLAETKIEARLTRIVTLADYC
GCGYGAKVTEALETYTRREGFYQLTIHSELTAQTFYENLGYQSYGPKCLE
DGEYCQSLAKTILKWEKNMDIAMLIAIVGGLLGCYLYLTKNN
>M28_Spy1075 transporter, MFS superfamily
MSTLSLDTTNKRALVAAIAASGTDDLNVMFLAFSMSSIMTDLSLSGTQGG
WIATITNLGMLVGGLLFGLLADRHHKFKVFKWTILLFSVATGLIYFTQSL
PYLYLMRFIAGIGVGGEYGVAIAIMAGIVPPEKMGRMSSLNGIAGQLGSI
SSALLAGWLAPSLGWRGLFLFGLLPILLVIWMTLAIDDQKIWDHYGQEEE
ECSQPIKINELFKTKSLTAQTLALMVMTTVQIAGYFGMMNWLPTIIQTSL
NLSVKSSSLWMVATIVGMCLGMLCFGQLLDCFGPRLIYSLFLLASSICVY
LFQFANSMASMVIGGAIVGFFVNGMFAGYGAMITRLYPHHIRSTANNVIL
NVGRALGGFSSVAIGSILDASGISMVMIFLASLYVISFGAMWSIGQLKAE
RYQQLR
>M28_Spy0912 nucleoside transport system permease protein
MVQFIRRKVMSKNAQKIAVPLISVLLGFLLGAIIMVIFGYDPIWGYEGLF
QIAFGSVKNIGEIFRSMGPLILIALGFTVASRAGFFNVGLSGQALAGWIS
AGWFALLNPDMPRPLLILMTALIGMIAGGIAGAIPGILRAYLGTSEVIVT
IMMNYIILYVGNAIVQRGYPESVKQSIDSTIQVSDNASYQTHWLSALTNN
SRINIGIFFAIIAIALIWFLLNKTTLGFEIRSVGLNPHASEYAGMSSKRT
IILSMIISGALAGLGGVVEGLGTFENVFVQGSSLAVGFDGMAVSLLAANS
PLGIFFSSFLFGVLNIGAPGMNIAGIPPELVKVVTASIIFFVGSHYLIER
YIIRPKKLVKGGK
>M28_Spy0217 GTPase
MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVDFSAEDN
SEGYILAIHPRKNSLVRPPIVNIDQAVVIMSAKEPEFNSNLLDRFLILLE
HKAIHPVVYISKMDLLDSPEEIKAIGRQYQAIGYDFVTSLEELLPLLADK
ITVFMGQTGVGKSTLLNRIAPELALETGEISDSLGRGRHTTRAVSFYNTH
GGKIADTPGFSSLDYDIANAEDLNEAFPELRRLSHECKFRSCTHTHEPKC
AVKAALETGELWPVRYEHYLQFLSEIENRRETYKKVIKRK
>M28_Spy0304 Fe-S oxidoreductase
MCYNRNMKKRYQTLNEHYRQLFGAKMFKVPIDAGFDCPNRDGTVAHGGCT
FCTVSGSGDAIVAPDAPIKEQFYKEIDFMHRKWPDVNRYLVYFQNFTNTH
DTVDVIRDRYEQAINEPGVVGINIGTRPDCLPDDTIAYLAELSERMHVTV
ELGLQTTYEETSRLINRAHSYDLYKETVRRLRHYPNINIVSHLINGLPKE
THDMMLENVRRCVTDNDIQGIKLHLLHLMTNTRMQRDYHEGRLKLLSQKD
YVSIICDQLEIIPKHIVIHRITGDAPRDMLIGPMWSLNKWEVLNAIDKEM
ERRGSFQGCKVD
>M28_Spy1253 phage protein
MVILPDYQGVGLGTRFLKSVAEIYSCQGFDFRIVTSAKNLINALNRNTNW
KLKSYDKGNTPTGNSSIKQLAKTTRKNVKIASFLFIRKN
>M28_Spy0451 hydrolase (HAD superfamily)
MIKLIATDMDGTFLAEDGTYNQEQLAALLPKLAEKGILFAVSSGRSLLAI
DQLFEPFLDQIAVIAENGSVVQYHGEILFADMMTKEQYTEVAKKVLANPH
YVETGMVFSGQKAAYILKGASEEYIQKTKHYYANVKVINGFEDMENDAIF
KVSTNFTGHTVLEGSDWLNQALPYATAVTTGFDSIDIILKEVNKGFGMEH
LCQALGIKKAETIAFGDNFNDYQMLEFAGRAIATENARPEIKVISDQVIG
HCNDGAVLTYLKGLV
>M28_Spy0704 cystathionine beta-lyase
MTIFMNNYIDLAKTYGGFTSLDTNYLNHLLASLTDQQKLAFITPPPSVIN
AYFAEIYQKQSPQAATDYYFNLSKALGLFTDQPSFEEEKPFVRLNLSGKA
YGFAYQNDQEVALVFSEKAEPKKPELFFELTQIFPQYMVYEDKGQLKMQA
KQFEQGECEDITPDDTLLSKIYRLANGITMLKGFNVEELWALSQTFSGQK
YYDFAQREFMIYITQ
>M28_Spy1383 hydrolase (HAD superfamily)
MVNIILLIVSALIGLILGYALISIRLKSAKEAAELTLLNAEQEAVDIRGK
AEVDAEHIKKTAKRESKANRKELLLEAKEEARKYREEIEQEFKSERQELK
QLETRLAERSLTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQLQVEK
LEEEKKAELEKVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDR
TVKTAKDLLAQAMQRLAGEYVTEQTITSVHLPDDNMKGRIIGREGRNIRT
LESLTGIDVIIDDTPEVVILSGFDPIRREIARMTLESLIADGRIHPARIE
ELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPDLIKIMGRLQFRTSFGQN
VLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDREVEGSHVEI
GMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGARN
ESMENYIKRLRDLEEIATSFDGVQNSFALQAGREIRIMVQPEKISDDQVV
ILSHKVREKIENNLDYPGNIKVTVIREMRAVDYAK
>M28_Spy1466 guanine-hypoxanthine permease
MEKFFKLSENGTTVSTEIMAGLTTFFAMSYILFVNPSILGAAGMPSNAVF
LATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFALGFSWQEAL
AMVFICGLFNIFITVTKFRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNA
NIITFSISAENIVMVNGVEPAKASAKTFADGLLFVDANGGVVPTISSFTD
SSVLLAIFGLLLTTALVIRNFRGAILIGIVATTLVGIPLGIVDVSNLNFG
ISHIGEAWTELGTTFLAAFDGLSSLFSDSSRLPLVFMTIFAFSLSDTFDT
IGTFIGTGRRTGIFSQDDENALENSIGFSSKMDRALFADAIGTSIGALVG
TSNTTTYVESAAGIAEGGRTGLTAVSTAVCFLLSILLLPLVGIVPAAATA
PALIVVGVMMVSSFLDVNWSKFADALPAFFAAFFMALCYSISYGIAAAFI
FYCLVKVVEGKTKDIHPIIWGATFLFIVNFIILTIL
>M28_Spy0283 acetyltransferase GNAT family
MLIRQVQGSDLEVIATIESDNFSPQEATTRAVLEERIRLIPDTFLVALID
QEIVGYIEGPVVTTPILEDSLFHGVTKNPKTGGYIAITSLSIAKHFQQQG
VGTALLAALKDLVVAQQRTGLILTCHDYLISYYEMNGFINQGISESQHGG
TLWYQMIWKL
>M28_Spy0724 ABC transporter permease protein
MRKNMIISSVSQGLIWGVLGLGIYLTFRILNFPDMTTEGSFPLGGAVAVT
AISLGWNPFLSTLLGMLSGALAGFLTGLLYTKGKMPTLLAGILVMTSCNS
IMLMVMGRANLGLHDHKRIQDCLPFSIDLNSLLTGLITVVIVISVLIYFL
YTNLGQAYIATGDNKDMAKSFGINTDWMEVMGLVVSNSLIALSGALVSQQ
DGYADVSKGIGVIVIGLASIIVGEVLYSTGLTLLERLIAIVIGSILYQFL
ISVVITLGFNTSYLKLISALVLALCLMIPVVKERYFKGVRLTR
>M28_Spy0135 nucleoside-binding protein
MNKKVMSLGLVSTALFTLGGCTNNSAKQITDNSLKIAMITNQTGIDDKSF
NQSAWEGLQAWGKENKLEKGKGYDYFQSANESEFTTNLESAVTNGYNLVF
GIGFPLHDAVEKVAANNPDNHFAIVDDVIKGQKNVASITFSDHEAAYLAG
VAAAKTTKTKQVGFVGGMEGDVVKRFEKGFEAGVKSVDDTIKVRVAYAGS
FADAAKGKTIAAAQYAEGADVIYHAAGGTGAGVFSEAKSINEKRKEEDKV
WVIGVDRDQSEDGKYTTKDGKSANFVLTSSIKEVGKALVKVAVKTSEGQF
PGGQITTFGLKEGGVSLTTDALTQDTKKAIEAAKKAIIEGTITVPEN
>M28_Spy0817 glutamine amidotransferase, class I
MTKPIIGITANQRLNMALDNLPWSYAPTGFVQAVTQSGGLPLLLPIGDEA
AAKTYVSMVDKIILIGGQNVDPKYYQEEKAAFDDDFSPERDTFELAIIKE
AITLKKPILGICRGTQLMNVALGGNLNQHIDSHWQEAPSDFLSHEMIIEP
DSILYPIYGHKTLINSFHRQSLKTIAKDLKVIARDPRDGTIEAVISTNDA
IPFLGVQWHPELLQGVRDEDLQLFRLFVNDF
>M28_Spy1504 hydrolase (HAD superfamily)
MTVKAVFFDIDGTLLNDRKNIQKTTQKAIQQLKKQGIMVGLATGRGPGFV
QPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSMIYKVIRYANEKKRE
ISLGTASGLAGSRIIDMGTSPFGQVISSFVPKSWARTVEGSFKHLIRRIK
PQSFRNLVTIMREPIYQVVLVASQAETKKIQEKFPHIKITRSSPYSLDLI
SVDQSKIKGIERLGEMFGFDLSEVMAFGDSDNDLEMLSGVGIGIAMGNAE
TVVKDGAHFTTDSNNNDGISKALAHYGLIHFDIEKSFKSRDENFNKVKDF
HRLMDSDTIETPRSYTISEAGYRSGFKVEEIVEFLYAASKGDQQQFTQAI
FDLHGAVDQAANKVQAKKHVETPLIGQVDALADLLYFTYGSFVLMGVDPQ
PIFEAVHEANMAKIFPDGKAHFDPVTHKIQKPDYWQERHAPEVAIKKELD
KQLQKSLQRFDK
>M28_Spy1637 hypothetical membrane spanning protein
MSYKDLKEKRIMFDSKQNLAKSQWGFIVITAVMDLVVIVATLLAKTSFQR
YLVGGVAVILTSFLILLVWGLKTAKKLQTRLDSKEVLDSKVRDDQKLPRY
DERQKQILLKGYTIGFWFMIVAVWLSIFLHRFSERLVSASFLFTLALWGG
LAVQTTYCNLNGVSPFVDRRFGKQGILVGMIATGMSLITIGLAVREMMAG
QLKMGSFFKAGGSGSLMVLGITLLSMGASIFYRHYLDAKEADE
>M28_Spy0315 polysaccharides and teichoic acids export protein
MSTEKKQLTQEELMVQGAAWSTAGNFISRLLGVLYIIPWYIWMGQYAIQA
NALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQTEHSYQLIRSTL
KLMLGLGLIFSAIMYLGSPLFASLSGGDDTLVPIMHSLSLAVFIFPVMSV
IRGIFQGHNNIKPYAISQIAEQLIRVIWMLLTTFLIMKLGSGDYASAVTQ
STFAAFIGMVASMGVLGYYLWKQGLLAAIFSKPDHTVSIDIKGLLLETLK
ESIPFIVTGSAIQAFQLIDQWTFVNTMTLFTDYSRSQLLVLFGYFNANPA
KITMVLIAVAASIGGVGIALLTENYVKKDMKAAARLIINNIEMLVMFLLP
ALTGAIILARPLYSVFYGASEDRAIHLFVAVLFQTLLMALYTLFSPMLQA
LFENRKAIYYFAYGILIKLVLQIPLIYLLHAYGPLLATTIALVVPIYLMY
RRLYQVTHFNRKLLQKRLLLTLIETLLMGLVVFVANWLLGYVFKPTGRLT
SLLYLLIIGGLGMTVYTALTLLTHQLDKLIGSKASRLRQKLGWH
>M28_Spy1388 D-beta-hydroxybutyrate dehydrogenase
MTHTKEVAFITGAASGIGKQIGETFLKEGKTVVFSDINQEKLDQVVADYT
KEGYDAFSVVCDVTKEEAINAAIDTVVEKYGRIDILVNNAGLQHVAMIED
FPTEKFEFMIKIMLTAPFIAIKRAFPTMKAQKHGRIINMASINGVIGFAG
KSAYNSAKHGLIGLTKVTALEAADSGITVNAICPGYVDTPLVRGQFEDLS
KTRGIPLENVLEEVLYPLVPQKRLIDVQEIADYVSFLASDKAKGVTGQAC
ILDGGYTAQ
>M28_Spy1020 phage protein
MAIEIFGPEFRKKLLEDLIALNMEAIKIAQTKNAKSIEWITMKRLEKETG
WGRTKLTQWREQGKFNFKRSSENGKVLYDLADVNRFLRTSGYEKGETT
>M28_Spy0398 ATPase
MTTMTIAKGSQPIALQLGMLNRHGLIAGATGTGKTVTLKVLAEQLSLAGV
PVFLADIKGDLSNLTKAGEVTDKLAARLATIGVSDYQPQAFPVRMWDVFG
QNGQPLRTTISEMGPMMLSRLLNLNDTQTGVLNIVFKIADEKGWLLIDLK
DLQAILKEVGDHASDYSSHYGNIAKQSIGAIQRSLLTLEQEGAHQFFGEP
ALDVADLMQLDVASGYGAINILSATKLFQSPTLYTTFLLWLLSELYELLP
EVGDLDKPKMVFFFDEAHLLFKDAPKVFLEKVEQIVRLIRSKGVGIFFVT
QNPLDLPETVLAQLGNRIQHALRAYTPKEQKAVRVAADTFRQNPDLDVAR
VITELEVGEALISVLNDKGQPSIVERAYIMPPKSSFAVLSEIESQQLVQS
SPFASKYSQSIDRESAYEKLAAKVLEDNRLAQEAIATAKREKEAKEAIKA
QAATKKASRRSVGRPRKTVVEKATDAFISTTVRTIGRELVRGLLGSLRKR
>M28_Spy0633 hypothetical cytosolic protein
MITQEMKDLINNQLAMVATVDAKGQPNIGPKRSMRLWDDKTFIYNENTDG
QTRINIEDNGKIEIAFVDRERLLGYRFVGTAEIQTEGAYYEAAKKWAQGR
MGVPKAVGIIHVERIFNLQSGANAGKEINSESN
>M28_Spy1129 oxalate/formate antiporter
MEKTKRYIIATAGILLHLMLGSTYAWSVYRNPILQETGWDQAPVAFAFSL
AIFCLGLSAAFMGNLVEQYGPRLTGTVSAILYASGNMLTGLAIDRKEIWL
LYIGYGVIGGLGLGAGYITPISTIIKWFPDKRGMATGFAIMGFGFASLLT
SPIAQWLIETEGLVATFYLLGLIYLIVMLFASQLIIKPTAAEIAILDKKR
LQNNSYLIEGMTAKEALKTKSFYCLWVILFINITCGLGLISVVAPMAQDL
TGMSPEMSAIVVGAMGIFNGFGRLVWASLSDYIGRRVTVILLFLVSIIMT
ISLIFAHSSLIFMISIATLMTCYGAGFSLIPPYLSDLFGAKELATLHGYI
LTAWAIAALTGPMLLSITVEWTHNYLLTLCVFIVLYILGLMVALRLKK
>M28_Spy1343 SAM-dependent methyltransferase
MVTKEVGHDFLARLGKKRLRPGGVEATNWLIEQGQFSQDCHVLEVACNRC
TTAIELAKTFGCQIDAVDLNPKVVKEAQERVTVEGLTRHITVSQANALSL
PFPDNHFDIVINEAMLTMLNAKAKEKALNEYWRVLKPGGRLLTHDVAYED
PKTRQVLDELRQTIHVNVAPLSLTGWQALYQEHGFSQVTYHHGKMSLMTP
RGMIKDEGLMNTLNIMRRGLKKENRQQFLKMRRFFTRTGKNLCYIAVKSV
K
>M28_Spy0305 SAM-dependent methyltransferase
MTDLDRRKVMLKRPIHLSHDFLAEVVDKSSVVVDATMGNGNDTAFLAQLA
KKVYAFDVQEQAIRKTSERLAQLGLSNAELILAGHEAVDQYVTEPVRAAI
FNLGYLPSADKSIITLPNTTLQALSKLLTLLMVGGRIAIMVYYGHDGGSL
EKDALLDFVKQLDQRKVSAMLYQPLNQVNTPPFLIMLEKLADV
>M28_Spy1123 CaaX amino terminal protease family
MKGFINYLKIAVLIILAMVFNVLPMILLQKQHDIPMVLNWGIGIFYLVIV
GSVLIVLWRLYQAKQDTPIKQQKMRLVDWGYLALFWLIIRVIAIAGTLVN
QLWSGQQVSANDAAIHTLARLIKGGFPLYTALFVLVIAFIAPIMEELVFR
GFPMIDLFKGKSLKVAGLVTSLVFALPHATNSVEFIMYSCMGIFLFVAYQ
RRGNLKDAILLHIFNNLIEVILLMSIGLGVI
>M28_Spy1711 ABC transporter ATP-binding protein
MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGKSTLMNI
IGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTA
CQNVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRV
AIARALVTNPSFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHE
PEVAALCKKTVILRDGNIEHSDIE
>M28_Spy0253 GTP-binding protein
MEELFCIGCGIQIQTEDKEKAGFTPAAALKKGMETGELYCQRCFRLRHYN
EITDVHITDDEFLRLLHEVGDSDALVVNVIDIFDFNGSIIPGLSRFISGN
DVLLVGNKKDILPKSVKDGKVTQWLTERAHEEGLRPLDVMLTSAQNKYAI
KDLIERINELRNGRDVYVVGVTNVGKSTLINAIIQEITGDKDVITTSRFP
GTTLDKIEIPLDDGSFIFDTPGIIHRHQMAHYLSPKELKIVSPKKEIKPK
TYQLNPEQTLFLGGLSRFDFINGERQGFTAFFDNQLELHRTKLAGADAFY
DKHVGTLLTPPGKKELTAFPKLVRHEFTIDQKMDIVFSGLGWIRVNGQKD
SKAIVAAWAPEGVAVIVRKAII
>M28_Spy0289 hydrolase (HAD superfamily)
MHYTEDKEYMEHVGHLIAHPRFQKLSHIVQHQHSTRLEHSINVSYSSYKL
AKRFGWDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLT
ELNKKEEDIILKHMWGATIAFPRYKESYIVTMVDKYWAVKEAVTPLRQKW
SNRRFLRRKTLQSHNR
>M28_Spy0454 multidrug resistance protein B
MSHHQQTVSKQTIMAIIAIALIGFSGILSETSMNVTFPTLMSVYQLPLNS
LQWMTTIYLLAVAIMMTTSATLKKNVRERPLFFMATGLFTFGTILAVLTQ
SFAIMLLARIFQGIGTGLVMPQMFNIILERVPMHKVGLFMGFAGLIISLA
PAFGPTYGGFMISHFSWQWIFICILPVPLIAGILAYYYLEDSPVSEKVPF
DWLAFIALSISLTSALLAITSLENGSVNLYYLGLFILSFVLFLYKNLTAK
QPFLDIRILKIPSLTFGLIPFFVFQLINLGINFLTPNFIVMEKIANSSQA
GMVLLPGTLLGALLAPAFGKLYDQKGAKLSLYLGNALFSLSLIIMTLQTR
HFMLLPFTLLYILFTFGRNMGFNNSLATAIRELPAEKNADATAIFQMMQQ
FAGALGTAMASLIANSQPEFTSGVQSVYLLFTIFALLDFIFFFAMFYHLG
KKGLA
>M28_Spy0718 hypothetical membrane spanning protein
MPLIPDKSRTDSLFYKWFLNNQATMALVITLLAFLTIFVFTKISFLFMPV
ISFFAVIMLPLVISTILYYLTKPLVDLINHLGPNRTTSIFIVFGLITLLF
VWAISGFVPMVQTQLTSFIEDLPKYVGKVNEEANKLLENEWLVSYKPQLQ
DMLTHTSQKALDYAQSFSKNAIDWAGNFAGAIARITVAIIISPFILFYFL
RDSSHMKNGLVNVLPLKLRVPMVRVLGDINKQLSGYVQGQVTVAIVVGFM
FSIMFSLVGLKYAITFGIIAGFLNMIPYLGSFLAMIPVVIMAMVQGPFML
VKVLVIFMIEQTIEGRFVAPLVLGNKLSIHPITIMFLLLTAGSMFGVWGV
FLVIPIYASVKVVIKELFDWYKKVSGLYDEEVLVIEEVKDHVK
>M28_Spy1015 phage protein
MKITKATEITKTHNWRILIYGKPGNGKTYLTNYLKGKTLILDMDHSSKTI
AGNENIDIIQFDRTHPSDFMTEFLTELPELIKEYDNLVIDNITSWQSDWF
IEQGRKSKNGITNELQQYNMWTNYYLRVLTTIYSQPTNIFVTAWESTQDL
TLESGQIITQYVPDIRKQVLSQTLGLTDVVGRIQVNPKTGGHGILLQGSD
GLYAKNRLDNRTVCKAEELFNFEGSDA
>M28_Spy0914 nucleoside-binding protein
MNKKFIGLGLASVAVLSLAACGNRGASKGGASGKTDLKVAMVTDTGGVDD
KSFNQSAWEGLQSWGKEMGLQKGTGFDYFQSTSESEYATNLDTAVSGGYQ
LIYGIGFALKDAIAKAAGDNEGVKFVIIDDIIEGKDNVASVTFADHEAAY
LAGIAAAKTTKTKTVGFVGGMEGTVITRFEKGFEAGVKSVDDTIQVKVDY
AGSFGDAAKGKTIAAAQYAAGADVIYQAAGGTGAGVFNEAKAINEKRSEA
DKVWVIGVDRDQKDEGKYTSKDGKEANFVLASSIKEVGKAVQLINKQVAD
KKFPGGKTTVYGLKDGGVEIATTNVSKEAVKAIKEAKAKIKSGDIKVPEK
>M28_Spy1421 NADH peroxidase
MAIIGQLLCFFFIGLGKTLSYLKNNCYNNTIMTLTTKTIHVIGASFAGLA
FVDKYKDLNPDSQIILIDKESCPNYIPNGINQLFRGDIQDLSDAMWGRAC
LAAQIESNHRFIQAEVLAIEAPSNTLLLKDSQGRVFEEGYETLVCAMGAS
PQSHYIETSQTNKVLVTKYYEESQASLKLIEASQEVLVIGAGLIGLDLAY
SLSLQGKRVKLIEAAERPDFYQTDAELIAPVMAEMSTHHVTFINNKRVTA
IHEIEGKVVAHTEQGDTFQGDLAILAINFRPNTHLLQGQVACALDKTILV
NENLQTSQANIYAIGDMVSLYFGILGMDYYTPLINQAMKTGQALALHLAG
YPIPPLQTVKVLGSSHFGYYRASVGVTEEEAELYMDTCSYLYQNGDSKNL
FWLKLIARKTDGILIGAQLLSKTNALVIANQLGQALALKVTDGDLAFQDF
LFLQGHSDLAYHLHEACLKLFEKRLRHED
>M28_Spy1144 methyltransferase
MKADFSKVKITLQTFTSSLFYVKITGMIKAILKEGERIDQLFSSDVGIIQ
NKDVFSYSIDSVLLSRFPKMPSKGLIVDLCSGNGAVGLFASTRTKAAIVE
VELQERLADMGQRSIQLNQLEDQVTMICDDLKNLLNHVPRSGVDLMLCNP
PYFKSHESSKKNVSEHYLLARHEVTTNLEEICQVARHALKSNGRLAMVHR
PDRFLEIIDSLRANGLAPKRVQFVYPKLGKSANMLLIEAIKDGSIEGMTI
LPPLVVHKENGEYTDHIFEIYFGAASKGKPNHDH
>M28_Spy1805 phage protein
MKDYQNKLSQATQPAFAPAFRTRKGRGDKEYVISSPYNVGKVFEFYENIY
TGIKYNEFEKTIEITKAVPWSKEKGLWTNEQTSLCIAFIDEKYRFTPRKE
HIEVAITALAKKNTYHPIKQRIESQKWDGKARGERYFIDLLGCADNSYNR
EIAKVWLTGLMARIYLRKVKFEVVPILIDKRQGTGKSTVTKRLLPSYHTD
SEIKFGKNDSDYQKIQANAIIELGELKGMSKAEIETVKSFISSDSDTYRE
PYERKATPHPRHCVFIGTANKKSFLKDSGTERRFFPIECGINDVKKHPME
VEEDYFLQVLAEAKVWFNNYEPLTPSKELMNQLADIQEDYKVEDVDKEII
DQLLNEFQIVEGWDSLSQYEQRQYILKQLGEPLDNAQSYSDYPSAQTDCL
LQVTSPNHIAYLGFNQKPTQGGKALISQKIRDYLDNDDGWKKGENPARKR
LFKGGTPVPYYERV
>M28_Spy0507 beta-phosphoglucomutase
MLMIKGIIFDMDGVLFDTEPFYLRRREDFFKTKGIPIDHLNSKDFIGGNL
QELWKELLGKNRDDAIVKAITTDYDAYKQAHKPPYQKLLITEVNSCLEQL
KKQGIKLAVASNSKRQDVLLALETTQIKDYFEIILAREDVSRGKPYPDIY
NKAVQKLGLQKKQLLVVEDSEKGIAAAKAANLTVFAITDYRYGIDQSQAD
HKIDHLGQLCVKIGCFGS
>M28_Spy0835 4-oxalocrotonate tautomerase
MPFVTIDLFEGRSQEQKNQLAREVTEVVSRIAKAPKENIHVFINDMPEGT
YYPQGEMKQKS
>M28_Spy0827 short chain dehydrogenase
MKVRKCMGNIALVTGASAGFGRAIVEQLIADGIKVIGASRRLEKLKALET
SFGSDNFYPLQMDVTDTKAIDDALTSLPNQWQDITILVNNAGLALGLDKA
YEADFENWMTMINTNIVGLIYLTRQLLPHMVSKDDGIIINLGSTAGTIPY
PGANIYGASKAFVKQFSLNLRADLAGTHIRVTNIEPGLCDGTEFSKVRFN
GDEARVKAIYQGAHAIQPQDIASTVSWVIHQPPHVNVNRIELMPVSQSYG
PQPVSRD
>M28_Spy1894 ABC transporter ATP-binding protein
MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFLKILAGD
IEPSTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYNIMKEKD
AIYMKADFSEEDGVRAAELEGIFAELGGWEAESEASQLLQNLNIPEDLHY
QNMSELANGDKVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLID
FENTVIVVSHDRHFLNKVCTHMADLDFGKIKLFVGNYDFWKQSSELAARL
QADRNAKAEEKIKELQEFVARFSANASKSKQATSRKKMLDKIELEEIVPS
SRKYPFINFKAEREMGNDFLTVENLSVTIDGEKIIDNISFILRPGDKAAI
IGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSKDFATEESI
LEWLRQFASKGEDDDTFLRGFLGRMLFSGDEVKKSVIVLSGGEKVRVMLS
KLMLLKSNVLILDDPTNHLDLESISSLNDGIKDFKESVIFASHDHEFIQT
IANHIVVISKNGVIDRIDETYDEFLDNPEVQARVAELWK
>M28_Spy1465 ATP/GTP hydrolase
MFYSENEYTLKAYGETLGTYLSIGDVIVLSGDLGAGKTTLAKGIAKGMGI
SQMIKSPTYTIVREYEGRLPLYHLDIYRVGDDPDSIDLDDFLFGNGVTVI
EWGELLGEGLLQDYLQITITKRDKGRQLDLLAHGERSRQLLEIMSHDSAK
SRY
>M28_Spy0294 putative phosphoesterase
MASKTIIVMSDSHGDRDIVQAIKDKYLGQVDAIFHNGDSELNSSDPIWAG
IYVVGGNCDYDTGYPDRLVTQLGTVTIAQTHGHLYHINFTWDKLDYFAQE
VAADICLYGHLHRPAAWQVGQTLFMNPGSVTQPRGEINEKLYARVELTDT
QIKVDYFTRDHKLYPSLSKEFKR
>M28_Spy1871 phosphohydrolase
MIVRNGKNFLTRDAADQYYTIGGTSLVGEKTHETVLRETLEEVGIRTKVN
QLAFVVENHFDIDDVFWHNIEFHYLVSPLEDPKLEMIENASDRFVNGFQS
INWIK
>M28_Spy1587 Zn-dependent hydrolase
MTNISLKPNEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFPEDDLL
GIDYVIPDYSYIVDNLDRVKALVITHGHEDHIGGIPFLLKQANIPIYAGP
LALALIRGKLEEHGLWREATVYEINHNTELTFKNMSVTFFKTTHSIPEPV
GIVIHTPQGKIICTGDFKFDFTPVGDPADLQRMAALGEEGVLCLLSDSTN
AEIPTFTNSEKVVGQSILKIIEGIHGRIIFASFASNIYRLQQAAEAAVKT
GRKIAVFGRSMEKAIVNGIELGYIKVPNGTFIEPSELKNLHASEVLIMCT
GSQGESMAALARIANGTHRQVTLQPGDTVIFSSSPIPGNTTSVNKLINTI
QEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVHGEYRMQKV
HAGLAMDIGIPKENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
DIGAAVLRDRRDLSEDGVVLAVATVDFNTQMILAGPDILSRGFIYMRESG
DLIRESQRVLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPII
IPMVLTPDKH
>M28_Spy0154 metal-dependent hydrolase
MTKVQDITRESWILNTFPEWGTWLNEEIEQEVVPADNFAMWWLGNCGIWI
KTPGGANVVMDLWSNRGKATKQVKDMVRGHQMANMAGARKLQPNLRAQPM
VIDPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLNHVKFVGPYECGE
VWKNWGVPKDRIMILKPGDSFEFKDIKITAVESFDRTCLVTLPIQGADAQ
DGDLAGLAITDDDMARKAVNYIFETPGGTIYHGADSHFSNYFAKHGRDYD
IDVVLNNYGENPIGIQDKMTSVDLLRMAENLRAKVVIPVHYDIWSNFMAS
TDEILELWKMRKERLQYDFHPFIWEVGGKYTYPQDQNRIEYHHPRGFDDC
FLEDSNIQFKALL
>M28_Spy0729 ABC transporter ATP-binding protein
MIILQGNKLERSFSGDVLFQNISLQVDERDRIALVGPNGAGKSTLLKLLV
GEETPTSGEVNTKKDLTLSYLAQNSRFESDKTIYEEMLKVFEALRQDEKR
LRQMEMDMATVSGQDLTRLMMDYDLLAERFRQQGGFTYEAEIKAILNGFK
FDESMWQMTIAELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAW
LENYLANYQGALIIVSHDRYFLDKVATVTLDLTPHGLDRYVGNYSRFMTL
KAEKLVAEEKQFDKQQKEIAKLEDFVQKNIVRASTTKRAQARRKQLEKIE
RLDKPTSARKSAHMTFQADKPSGNVVLTVEKAAIGYNQHVLSEPINLDVH
KLDAIAIVGPNGIGKSTLIKSVIGQIPFIKGEVKYGANVEIGYYDQTQSH
LTSSNTVLEELWQDFSTTPEVDIRNRLGAFLFSGDDVKKSVAMLSGGEKA
RLLLAKLSMENNNFLVLDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDR
YFINRLATKVLEITENGSTLYLGDYDYYLEKKAELEELARLAAGETVEET
KEASATDYQLQKANQKERRRLTRRYEEIEARLETIEERIGAIQEDMHASN
DTAQLIAWQKEWDQLDQEQETLMEEWETIAEQIES
>M28_Spy1230 phage protein
MQLTIKNKDLNTLYCVLDKIKVTNMRANRGRAKLLAKVVDKFKEYAKDEG
DLIDLYAQKDKDGKFVIDEHKNIKLADPTKLDEFSGLLNELADEEIVIKG
GEYSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGE
>M28_Spy0697 rhodanese-related sulfurtransferases
MSEKIRVLLYYKYVSIENAQEYAAKHLEFCKSIGLKGRILIADEGINGTV
SGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLG
LEDNNFDSDINPLETTGEYLNPKQFKEALLDEDTVVLDTRNDYEYDLGHF
RGAIRPDIRNFRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWMVRE
GFKDVGQLHGGIATYGKDPEVQGELWDGAMYVFDDRISVPINHVNPTVIS
KDYFDGTPCERYVNCANPFCNKQIFASEENETKYVRGCSPECRAHERNRY
VQENGLSRQGWAERLEAIGESLPEFVGA
>M28_Spy0725 ABC transporter ATP-binding protein
MTKIIELINATVDVDNGFEDAKTILDNVTLTIYEHDFLTILGGNGAGKST
LFNVIAGTLSLTRGQIRILGQDVTHWPAEKRALYLSRVFQDPKMGTAPRM
TVAENLLIARQRGEKRSLASRKITEHLASFEDLVKRTGNGLEKHLETPAG
LLSGGQRQALSLLMATLKKPALLLLDEHTAALDPKTSQSLMQLTDEFVTK
DGLTALMITHHMEDALTYGNRLIVMKDGNIIKDLNQMEKEQLTITDYYQL
FD
>M28_Spy0475 hydrolase (HAD superfamily)
MITAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSVMNQAYIRFRHYSDVG
FPRVMAGEWTTEYFRFWRCKETLLEFGYREIDEAAGVHFQEVYEHELENI
TMLDEMRMTLDFLKSKNVPMGIITNGPTEHQLKKVRKLGLYDYIDPKRVI
VSQATGFQKPEKEIFNLAAEQFDMNPQTTLYVGDSYDNDIMGAFNGGWHS
MWFNHRGRQLKPGTKPVYDVAIDNFEQLFGAVKVLFDLPDNKFIFDVNDK
KNPILQMGINNGLMMAAERLLESNMSIDKVVILLRLTKQQEKVLRLKYAR
>M28_Spy0630 RNA binding protein
MDTIENLIIAIVKPLISQPDNLTIKIEDTPDFLEYHLDLDAQDIGRVIGK
KGRTITAIRSIVYSVPTLGKKVRLVIDEK
>M28_Spy0840 phosphinothricin N-acetyltransferase
MLRPLSKTDCPMLQEINAKALGYLVSLDLLERQYERLIEDCHHYFLAYAD
KDTNQLLGYVHAERYETLYASDGLNLLGLAVLPAYQRRGIGSALLRALES
QARQEGIAFIRLNSASHRKEAHAFYRNLDYADDKTQLRFIKNLQGDDNDF
>M28_Spy0176 metal-dependent hydrolase
MKLTTLGSWGAYPYQDAGTTSYLVTGHDGFQLLMDAGSRALNELEKEISP
LDLDAVIISHYHPDHVADLGVLRHYFQLYPKHLWQPKVLPIYGHDEDRHE
FAKLSIPDVSEGRAYDVTGVEQIGPFDITFLKTVHPVVCYAFRIVERATG
QVLVFTGDSGYFEGLADFAKEADLFLADVYLYEGNENHMAHLTSKEAGLM
ASQAGVKKLVLTHMPPVPPEGIDPDNHLEVLRQETQAYAGNIPVDLALPH
KSWNLGSLS
>M28_Spy0258 methyltransferase
MLQRDLVNTTGFLRMIMKHNYEKFASVYDAVMDDSLYDLWTDFSLRHLPK
SKGRNRLLELACGTGIQSVRFAQAGFDVTGLDLSQDMLAIAKKRAQSAKK
KIDFIQGNMLDLSQVGQFDFVTCYSDSICYMQDEVDVGDVFKEVYDVLAN
DGIFIFDVHSTYQTDECFPGYSYHENADDFAMVWDTYADEAPHSVVHELT
FFIQEDDGRFSRFDEVHEERTYELLTYDILLEQAGFKSFKVYADFEDKEP
TKTSKRWFFVAYK
>M28_Spy0078 bis(5'-nucleosyl)-tetraphosphatase(asymmetrical)
MTECIFCHQLKANQLLTQSQYFKVVFDIDPIQKGHLLLISKDHYTSLTQL
PKEVRYDLIDLQAALVAKLEQHLPISGVTSVSNDKELMDEGTHFHLHLIP
RLTNDSFWESITINQENWDLTPFLKHL
>M28_Spy0432 hypothetical protein
MSRNQDCKNILIIGFGKIGKIKAYKWLSRGYEVYVKDLKFSSMKYLNTNS
DVLDDLSRQYFTIEICTPTNHHLTLLKTVITRYVYSYISIEKPLCNRLED
LEEMKSLVESHPHLAKKMFASEQYFFSKILEKLLQVDCFSLDKIKEITVN
FSKDRIEDNENGRFLDKEILGYGIEIPHIIAVISYLGISLEEFKKGIFVN
AIYIKDLEKHDYSIEILSCINQTVIKIISNLGSFAIREGKIEGGDAKTVR
RVTIDDKTILFDPHPKLERYKSELVTGTNTFQIHDDMMDTYISLLEGNAI
PEDCYINNAIEITKLLINLYSECEKIYL
>M28_Spy0352 phosphohydrolase
MKFEEKTLKRQTVFDGHIFKVVVDDVELPNNLGQSKRELIFHRGAVAVLA
ITPERKILLVKQYRKAIERVSYEIPAGKLEIGEEGSKLKAAARELEEETA
YTGTLTFLYEFYTAIGFCNEKITLFLATDLTQVANPKPQDDDEVIEVLEL
TYQECMDLVAQGKLADAKTLIALQYYALHFGGEQ
>M28_Spy0654 ABC transporter ATP-binding protein uup
MSHFLVKKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTTLLDVLS
GRLGFDGDHSPFSKANDYKIAYLTQDPEFNDASSVLDTVLSSDVKAIQLI
RQYELLMANYTEDKQETLESLMSEMDRLDAWSIESDVKTVLSKLGITDLE
QKVGDLSGGMRRRVQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKT
AKKTVLFITHDRYFLDHVATRIFELDKAGLTEYQGNYQDYVRLKAEQDER
DATNLHKKKQLYKQELAWMRTQPQARATKQQARINRFTDLKKEVHQDSSA
DKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKDFNLIIQNKDRIGIVGD
NGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMDETKRVINY
LQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLK
LLIEKPNVLLLDEPTNDLDIATLTVLENFLANFAGPVITVSHDRYFLDKV
ATKILAFEEGDIRIFYGSYSDYLDEKAFEKETVEADLAKAIVTEEVPLPP
KEEKKRMSYLEKQEWAQIEDKIATIEANIEEIENQMLTVVSDYGQLAQLQ
KELDQRNNDLLLAYERFEYLSGLDI
>M28_Spy1775 putative oxidoreductase
MSMLNIGIVGLGAISQKAYLPYMRQLSDITWHLSTRNAAVRQQVGQLFGH
AILYSDVKELSKASLDGVFIHAATSAHAELASLFLNQGIPVFMDKPIADN
YLMTKNLYDLAKENQTFLMAGFNRRFTPRVKKLSSLSTKRKVAVEKNDLN
RPGDMTFKLFDFFIHPLDTALFLSEGTLLKGHFQYHLEAGLLSQVMVTLM
TESMTTTASMNLQSGSRREVMEVQRAEETYHLENLDELSIYKGTEKRVLG
FASWDTTLHKRGFETMIDAFLEAISTGVNPVSPESSLLSHWICQQIADSQ
LSYGELTVELPKD
>M28_Spy0377 phosphohydrolase
MAIMRKNTNIVKRDHMPQDYISYIRSKVGHDKIILNFAGGILTNDDGKVL
MQLRGDKKTWAIPGGTMELGESSLETCKREFLEETGIEVEAVRLLNVYTH
FEEVYPNGDAVQTIVFIYELTAVSDMAIDNFHNEETLKLQFFSHEEIAEL
ESVSAKHRLMLEEYFSDSFAMGH
>M28_Spy1685 acetyltransferase
MIPIKALKIKVETVMKIIEYKGNYRDDLIFMVLEAKNALRRIPSINPDLL
TIETSYLEKGDCFWLAVNEESRVIGSIAYSSIPKTNEVFLHRLFIKPSLK
HQGIGSQLLTFAEDYLRKIGKSHVRIHLGQPKEQWFESYRFYPKHGYQFY
DDTHLIKKLI
>M28_Spy1128 O-methyltransferase
MVKSYSKTANHNMRRPVVKEELVHYMRTRQKQITGFLAELEQFARQENIP
IIQPEVVAYFRFLLQSLQPKHILEIGTAIGFSALLMAENAPDATIVTIDR
NREMIDFAKANFAKYDSRQQIRLLEGDAADILSTLEGNFDFVFMDSAKSK
YIVFLPEILRLLKVGGVVILDDVFQGGDITKPIEDIRRGQRTIYRGLQSL
FDATLTHPNLTTSLVPLSDGLLMIRKNQADILLPD
>M28_Spy0469 hypothetical protein
MPAPLKKHNSVEQDDSYQESQSKFRDFQEFNGQSAKLKELVFFARIASFS
LITVLFAFVLLVMNLAPMFAFLFASIISLGITSLFAKVIKSLLM
>M28_Spy0997 terminase large subunit
MSMKTTYQTKPKLEIKVDLPKTIGIGYGAFWRSKNFYRVVKGSRGSKKSK
TTALNFIVRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNQLKVTHLFK
FNESLPEITVKATGQKILFRGLDDELKITSITVDVGLLCWAWFEEAYQIE
TEDKFSTVVESIRGSLDAPDFFKQITVTFNPWSERHWLKRVFFDEETKRA
DTFSGTTTFRVNEWLDDVDKRRYEDLYKTNPRRARIVCDGEWGVAEGLVF
DNFEVVDFDVEKTIQRVKETSAGMDFGFTQDPTTLICVAVDLVNKELWLY
NEHYQKAMLTDHIVKMIRDKNMHKSYIAADSAEKRLIAEIKSKGVSGIVA
SLKGKGSIMQGVQFMQGFKIYIHPSCEHTIEEFNTYTFKQDKEGNWLNEP
IDKNNHVIDAIRYALEKYHIRSNESNQFEVLRAGFGY
>M28_Spy1506 hypothetical protein
MISYLKADLFRIRQERLALFSCMLLVVIAVGVAYSFRKTPNQVIMIQIIN
IITDFVTLFFLTPARIFFSDDYNYRTINNVVVKQQNRTLIIIYKLLVSFG
LSLLFISLTYLLSALAFHLFTGQAYYGIVIDRMIKQLPFYIAIIALCQFL
FNILRKTYQSITAYILYVLLFDKVSATLANHFFKLDISPVLMFKHLSLSL
GDKHLSSTSILVAFGLTLCYLLGNVFLFSKRELK
>M28_Spy0273 hypothetical cytosolic protein
MMLAISEIRKHPDGLSFDRLCDVKSMLLERDQQIIDIKAVKAVGNVRYDK
GLYLLDYQLSYEVILPSSRSMVPVCLSEVQHIQELFIEATDLADKKELVE
DNLVLVLDKDAINLEESIVDNILLAIPLQVLTEEEKKSKELPAGQNWAVL
TEEDYQCLKEEKQKENNPFASLQGLFDE
>M28_Spy0290 integral membrane protein
MNDHVIYTQSDVGLNQFFAKIYSLVGMGVGLSAFVSYLMLYPFRENLISI
LVNQPMIYYGAAIIELILVFVASGAARKNTPAALPIFLIYSALNGFTLSF
IIVAYAQTTVFQAFLSSAAVFFAMSIIGVKTKRDMSGLRKAMFAALIGVV
VASLINLFIGSGMMSYVISVISVLIFSGLIASDNQMIKRVYQATNGQVGD
GWAVAMALSLYLDFINLFISLLRIFGRND
>M28_Spy0811 Zn-dependent alcohol dehydrogenases and related dehydrogenases
MNWLITSQPYKELNMKAATYLSTGNLQLIDKPKPVIIKPTYRPVGKNHSI
CGTDLHILGGDVPACKEGTILGPEGIGIVKEIGDAVTNFKIGDKVIISCV
TSCHTCYYCKRGLSSHCEDGGWILGHLINGTQAEYVHIPHADGSLYHAPD
TIDDEALVMLSDILPTSYEIGVLPSHVKPGDNVCIVGAGPVGLAALLTVQ
LFSPANIIMVDLSQNRLEAAKTFGATHTICSGSSEEVKAIIDDITNGRGV
DISMECVGYPATFDICQKIISVGGHIANVGVHGKPVDFNLDELWIKNITL
NTGLVNANTTEMLLNVLKVIIDNDIS
>M28_Spy0818 redox-sensitive transcriptional regulator Rex
MVIDKSIPKATAKRLSLYYRIFKRFHADQVEKASSKQIADAMGIDSATVR
RDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTNVILVGCGNIGRALL
HYRFHDRNKMQIAMGFDTDDNALVGTKTADNIPVHGISSVKERIANTDIE
TAILTVPSIHAQEVTDQLIEAGIKGILSFAPVHLQVPKGVIVQSVDLTSE
LQTLLYFMNQNHLD
>M28_Spy0452 hydrolase (HAD superfamily)
MNIRILALDLDGTLYNTEKIVTDANKKALAAAREKGVKVVITTGRPLKAI
GNLLEELDLLDHDDYSITFNGGLVQRNTGEVLDKSSLSFDQVCQIQQALE
AVGLPTDIISGGDVYSIPSKDGRHSQYHLANPLLTFIEVTSVAELPKDIT
YNKIVTVTDPDFLDQQIIKLSPSLFEDFEAFKSRDIIFEIMPKGIDKAFG
LNLLCQHLGLDARHVMAMGDEANDFAMLEWAGLGVAMANGVSGAKAVADA
VTTLTNDESGVAEAVKTFILEEES
>M28_Spy1272 phage protein
MTKQHRETLIWYRASHQERERLLDFGLVDKSQYVTLLRQLRKKYAI
>M28_Spy0602 methyltransferase
MNKLYIDSFVEKKLTAGVQLLDEKDFSNIKEKNQLVQLVTKSNRPIGTAY
ISKQNKGIGWYLGPEKIDLSISYFVSLFSVAKAKRQDFAQSDETNAYRLF
NQEGDGFGGVTIDLYKDFAVFSWYNAFVYDKKEMIMEAFQQVFPEVKGAY
EKCRFKGPDTETAHLYGELAQETFSILENGIAYQVFLNEGLMTGVFLDQH
DVRRALVDGLAMGKSLLNLFSYTAAFSVAAAMGGAIETTSVDLAKRSREL
SLAHFEHNQLNLASHHFVVMDVFEYFKYAKRKKLIFDVIVIDPPSFARNK
KQTFSVSRDYHKLITEALDILSPKGTIIASTNAANMTVSQFKKQIIKGFG
SRRPESMTLQQLPSDFTINKADERSNYLKVFTIKVRE
>M28_Spy0815 hypothetical membrane spanning protein
MIIKGVTMKFEKKQVFYLVLTFILCYGILANWRNGTAIVTTIYKTSLPFF
YGAAGAYIVNIVMSAYEKVYVYIFKDWSHVLKVKRGICLLLAYLTFFILI
TWIISIVIPDLITSISTLTKFDTITIQEVVNNLEHNKLLARTIQYIGGDG
KLTETIANYSQQLLKQFLTVLTNILTSVTVIASAIINLFISFVFSLYVLA
SKEDLCRQGNTLVDTYTGKYAKRIHYLLELLHQRFHGFFVSQTLEAMILG
SLTASGMFILRLPFAGTIGVLVAFTALIPVIGASIGAAIGFILIMTQSMS
QAIIFIIFLIILQQIEGNFIYPKVVGGSIGLPAMWVLMAITIGASLKGIV
GMIIAVPLAATLYQVIKDNIQKRQAIQKKQVS
>M28_Spy0445 ParE-domain protein
MKEYQVTMSDDAKADLLSIYHYVRDELCAPQAADNLLERLSQEMLSLSIF
PERCAIIEDLIGKGYTFRQLIVKKYRIVYHVLEDEVIIVAVVYGSRHMNN
W
>M28_Spy1550 colicin V production protein
MLSLLIVLVLTWNFYIGYSRGIILQSFYVLGALLSLLVANRFYIGLAHKL
TLWIPYSNPVEGTSVFFFKSVDIFVLDKVYYAGLAFFIIFLLGYALSRFL
GIFVHFLLLDYFDNQWTKCLSGGLALLVSLLFLNMLLSIFATVPMPFLQH
YLHSSFLARLVIEHLPPLTIIIQKLWIQAII
>M28_Spy0854 conserved membrane protein
MNQTFKQSLPLSFSEEVANSVTHAIGAFAMLILLPISASYAYQTYDLKAA
IGISIFVISLFLMFLSSTIYHSMAYGSVHKYILRIIDHSMIYIAIAGSYT
PVALSLVSGWLGYIIIVLQWGITLFGILYKIFAKRINEKFSLMLYIVMGW
LVVFILPVIIQKTSLAFGLLMLFGGLSYTIGAVFYAKKRPYFHMIWHLFI
LLASALQFIAITFFML
>M28_Spy0812 class B acid phosphatase
MKKEFTSILFTVSFCGIIALPVEASGPKVPYTQEGITAISNQATVKLISI
ADIASSLEGQKPITVSFDIDDTLLFTSQYFQYGKEYITPGSFDFLHKQKF
WDLVAKRGDQDSIPKEYAKQLIAMHQKRGDKIVFITGRTRGSMYKKGEID
KTAKSLAKDFKLDKPIAINYTGDKAVKPYQYDKTYYIKKNGSQIHYGDSD
EDINAAKEAGARPIRILRAPNSTNLPLPKAGGYGEEVLENSAY
>M28_Spy0552 diacylglycerol kinase family
MKKQLRARLIYNPTSGQELMRKSVPEVLDILEGFGYETSAFQTTAQKNSA
LNEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLKKRPKMAIIPTGTTND
FARALKVPRGNPSQAAKLIGKNQTIQMDIGRAKKDTYFINIAAAGSLTEL
TYSVPSQLKTMFGYLAYLAKGVELLPRVSNVPVKITHDKGVFEGQVSMIF
AAITNSVGGFEMIAPDAKLDDGMFTLILIKTANLFEIVHLLRLILDGGKH
ITDRRVEYIKTSKIVIEPQCGKRMMINLDGEYGGDAPITLENLKNHITFF
ADTDLISDDALVLDQDELEIEEIVKKFAHEVEDLEQELEE
>M28_Spy1283 phage protein
MMTPETVCQEKGIDLVYFDGRGTNIPGMFNKKHNVIAIDTYLDGIYKHKV
IYHELGHREHTASYYKLNKEKAELQADRCMIHHLLKEELSYWDNMEDFNY
IQFMEKYELTSIADEVMVKEEFKNLI
>M28_Spy0549 endonuclease/exonuclease/phosphatase family protein
MINKKYIIPVSLLTLAITLTSVEEVTSRQNLTYANEIVTQRPKRESVISD
KSNFPVISPYLASVDFGERKTSLPTPDKGVKVTTEQSIAQVRKGPEERTY
TVTGKITSVINGWGGYGFYIQDSEGIGLYVYPQKDLGYSKGDIVQLTGTL
TRFKGDLQLQQVTAHKKLELSFPTSVKEAVISELETTTPSTLVKLSHVTV
GELSTDQYNNTSFLVRDDSGKSIVVHIDHRTGVKGADVVTKISQGDLINL
TAILSIVDGQLQLRPFSLEQLEVVKKVTSSNSDASSRNIVKIGEIQGASH
TSPLLKKAVTVEQVVVTYLDDSTHFYVQDLNGDGDLATSDGIRVFAKNAK
VQVGDVLTISGEVEEFFGRGYEERKQTDLTITQIVAKAVIKTGTAQVPSP
LVLGKDRIAPANIIDNDGLRVFDPEEDAIDYWESMEGMLVAVDDAKILGP
MKNKEIYVLPGSSTRPLNNSGGVLLPANSYNTDVIPVLFKKGKQIIKAGD
SYKGRLAGPVSYSYGNYKVFVDDSKNMPCLMDGHLKPEKTNLQKDLSKLS
IASYNIENFSANPSSTKDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPT
DDGTTDATQSAQRLIDAIKKLGGPTYRYVDIAPENNVDGGQPGGNIRTGF
LYQPERVSLSDKPKGGARDALTWVNGELNLSVGRIDPTNAAWKDVRKSLA
AEFIFQGRKVVVVANHLNSKRGDNALYGRVQPVTFKSEQRRHVLANMLAQ
FAKEGAKHQANIVMLGDFNDFEFTKTIQLIEEGDMVNLVNRHDISDRYSY
FHQGNNQTLDNILVSRHLLDHYEFDMVHVNSPFMEAHGRASDHDPLLLQL
SFSKENDKAESSKQSVKAKKTSKGKLLPKTGDSLVYVITLLGTASLLVPI
LLLTKGKKES
>M28_Spy1594 predicted kinase
MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNMSMTMDN
GAKEVADKPASTVGEVGQMLSKGLLMGARGNSGVITSQLFRGFGQSIKGK
DELTGKDLAQAFQVGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTD
DAVEVMQAALDGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSA
LNGDYVTSADFKATPANMSEMINAEHHKSVVGHVATEDITYGYCTEIMVA
LKQGPTYVKEFNYDEFQGYLSGLGDSLLVVNDDEIVKVHVHTEDPGLVMQ
EGLKYGSLIKIKVDNMRNQHEAQVQKTDVEKNKAEVKEFGLIAVVAGEGL
SEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILPNNKNIFMA
AQSAAEVVDIPAAVVATRTVPQGFTSLLAFDPSKSLEDNVADMSTSLSDV
VSGSVTLAVRDTTIDGLEIHENDFLGMVDGKIIVSNPDMEATLKAAFEKM
IDEDSEIVTIFVGEEGDQDLAEELAGYLGETYEDVEVEIHQGDQPVYPYL
MSVE
>M28_Spy1200 radical SAM family enzyme
MKPSIYSLTRDELIAWAVERGQKQFRATQIWDWLYKKRVQSFEEMTNISK
DFVSILNDSFCVNPLKQRVVQESADGTVKYLFELPDGMLIETVLMRQHYG
HSVCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMLVQKYFDDRKQ
GERVSHVVVMGIGEPFDNYKNVMCFLRVINDDNGLAIGARHITVSTSGLA
HKIRDFANEGVQVNLAVSLHAPNNDLRSSIMRVNRSFPLEKLFSAIEYYI
EKTNRRVTFEYIMLNEVNDSIKQAQELADLTKTIRKLSYVNLIPYNPVSE
HDQYSRSPKERVLAFYDVLKKNGVNCVVRQEHGTDIDAACGQLRSKTMKK
DREKVTATK
>M28_Spy1577 NAD(FAD)-utilizing dehydrogenases
MTQYDTIIIGGGPAGMMAAISSSYYGYKTLLIEKNRRLGKKLAGTGGGRC
NVTNSGNLDDLMAGIPGNGRFLYSVFSQFDNHDIIAFFEENGVKLKEEDH
GRMFPTTDKSRTIIDALEKKIKALGGQVLTSTEVVSVKKQDDLFYLKSTD
QTFTCQKLIVTTGGKSYPSTGSTGFGHDIARHFKLTVTDLEAAESPLLTD
FPHKVLQGISLDDVTLSYDKHVITHDLLFTHFGLSGPAALRLSSFVKGGE
IAELDFLPHLSTDDLTAYLSDQRDKNIKNALKGLLPERVADFLSEDYPEK
VKQLSPKQEKELLDKLKHLQIPITGKMSLAKSFVTKGGVDLKEINPKTLE
SKKVPGLYFAGEVLDINAHTGGFNITSALCSGWIAGKSS
>M28_Spy1457 tRNA (m(7)G46) methyltransferase
MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIEVGSGKG
GFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSL
TNYFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIH
FKTDNRGLFEYSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNK
GQVIYRVEANF
>M28_Spy1882 metalloprotease
MKIVQGVQLHLIKTKQFKTNHITFRFSGDLNQKTVAKRVLVAQMLATANE
CYPTVRQFREKLARLYGASLSTNVLTKGLVHIVDIDITFIQDRYACNGEK
ILDEMIQFLKDILFSPLLSIAQYQPKVFETEKNNLINYIESDREDSFYYS
SLKVKELFYCNKNLQMSEYGSPELIAKETAYTSYQEFHKMLNEDQIDIFI
LGDFDDYRVVQLIHQFPLDNRNKNLNFFHLQNSVNIIKESIEKRAVHQSI
LQLAYHFPSVFGQRDYYALVLLNGLLGSFAHSRLFIKIREEEGLAYSIGC
RFDSYTGLFEIYTGIDSQHRTKTLQLIIQELNAIKMGRFSEQLIKKTRSM
LLNNALLSEDYNKNIIERIYTSSYIDSSYSIKNWIKGVNEVNKADIIKVA
NLLKLQTVYFLEGI
>M28_Spy0513 acetoin dehydrogenase
MTKKYEVEDMSKVAIVTGAGQGIGFAIAKRLHADGFKIGILDYNEETAQA
AVDKLSPEDTVAVVADVSKRDQVFDAFQKVVDTFGDLNVVVNNAGVAPTT
PLDTITEEQFEKAFAINVGGTIWGSQAAQKHFRELGHGGKIINATSQAGC
EGNPNLTVYGGTKFAVRGITQTLAKDLASEGITVNAYAPGIVKTPMMFDI
AHEVGKNAGKDDEWGMEQFAKDITLKRLSEPEDVANAVGFLVGDDSNYIT
GQTIVVDGGMVFH
>M28_Spy0706 short chain dehydrogenase
MAQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQHIDNKE
CLELDITNPVAIEKMVAQIYQRYGRIDVLINNAGYGAFKGFEEFSAQEIA
DMFQVNTLASIHFACLIGQKMAEQGQGHLINIVSMAGLIASAKSSIYSAT
KFALIGFSNALRLELADKGVYVTTVNPGPIATKFFDQADPSGHYLESVGT
FTLQPNQVAKRLVSIIGKNKRELNLPFSLAVTHQFYTLFPKLSDYLARKV
FNYK
>M28_Spy0525 phosphoesterase, DHH family protein
MITTFETILDKIKAHQTIIIHRHQNPDPDALGSQAGLKEIIAQNFPDKKV
LMTGFDEPSLTWISQMDQVTDKDYKEALVIITDTANRPRIDDERYTLGQC
LIKIDHHPNDDVYGDFYYVDTSASSASEIIADFAFSQNLTLSDKAAKLLY
TGIVGDTGRFLYASTTSKTLSIASQLRHFEFDFAAISRQMDSFPLKIAKL
QSYVFEHLTIDESGAAYVLVSQETLKHFDVTLAESSAIVCAPGKIDNVQA
WAIFVELTDGNYRVRMRSKEKIINGIAKRHGGGGHPLASGANSANLEENQ
AIFRELIAVCQEI
>M28_Spy0639 regulatory protein
MTTTDKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPNMAAAEF
LHIVQVFQFFTPIMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVI
QKGVATGTFQLRGIGDLINMMITASLAVLAVKYFGNKFGSLTIILLPITI
GTGVGYIGWKFLPYVSYVTTLIGQGINSFTTLQPILMSILIAVAFSLIIV
SPISTVAIGLAIGLNGMAAGAASMGIASTAAVLVWATLKVNKSGVPIAIA
LGAMKMMMPNFLKHPIMAIPMVFTAAISSLTVPLFNLVGTPASSGFGLVG
AVGPIASLAGGSSILIIILAWIIVPFAVAFAAHKVSKDILKLYKEDIFVF
EG
>M28_Spy0517 ATP-binding protein
MSDKHINLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALVPKFLELIE
QTNENRRVALVVDMRSRLFFKEINSTLDSIESNPSIDFRILFLDATDGEL
VSRYKETRRSHPLAADGRVLDGIRLERELLSPLKSMSQHVVDTTKLTPRQ
LRKTISDQFSEGSNQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYK
VELREKTGLDEDVFNYVMSHPESEVFYKHLLNLIVPILPAYQKEGKSVLT
VAIGCTGGQHRSVAFAHCLAESLATDWSVNESHRDQNRRKETVNRS
>M28_Spy0259 hypothetical cytosolic protein
MTVTGIIAEFNPFHNGHKYLLETAEGLKIIAMSGNFMQRGEPALIDKWIR
SEMALKNGADIVVELPFFVSVQSADYFAQGAIDILCQLGIQQLAFGTEDV
IDYQKLIKVYEKKSKQMTAYLSTLEDTLSYPQKTQKMWEIFAGVKFSGQT
PNHILGLSYAKASAGKHIQLCPIKRQGAAYHSKDKNHLLASASAIRQHLN
DWDFISHSVPNAGLLINNPHMSWDHYFSFLKYQILNHSDLTSIFQVNDEL
ASRIKKAIKVSQNIDHLVDTVATKRYTKARVRRILTYILVNAKEPTLPKG
IHILGFTSKGQAHLKKLKKSRPLITRIGAETWDEMTQKADSIYQLGHQDI
PEQSFGRIPIIIKNERLN
>M28_Spy0099 tRNA binding domain protein
MIFAYNKEQVGDVLMVILQDTKDIKRQVERKGKVARVFAEESGKTLAWNI
FEVSSLITIEGNGQIFLTDEDLARLNAELAKEGFSERLEPTVGPVFVVGQ
IVEMVAHPDSDHLNICQVAIGEDQTVQIVAGAPNAALGLKTIVALPGAIM
PNGSLIFPGKLRGEESYGMMCSPRELVLPNAPQKRGIIELDESAVVGEAF
DPAKHWKG
>M28_Spy0374 hypothetical metal-binding protein
MPNIPNEVGSPSLTINLMYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGK
EEKEMSVTFVTNERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDFA
ADPSLAEMMAEFDAYIGELFISIDKAREQSQEYGHSFEREMGFLAVHGFL
HINGYDHYTLEEEKEMFTLQEEILTAYGLTRQ
>M28_Spy0158 CoA binding protein
MIYSFQNPSEDILKAYLESAKTIAVVGLSDRKDTAAYGVAKFMQAMDYRI
IPVNPKLAGQLILGEKVYASIKAIPFEVDIVDVFRRSEFLPEVARDFLAG
QAKVFWAQLGLENQEVQTILRSAGKEAIVMNRCLKIDYLQLVAKPECITN
L
>M28_Spy1436 hydrolase (HAD superfamily)
MATVKNGTSLKSNGKRKDRMIQLIAIDLDGTLLNQDKQIPKENITAIQEA
AQSGLKIVLCTGRPQSGTRPYFDQLGLTQEEFLIINNGCSTYSSPDWQLR
HSKMLKVSDIELLEELSQSFPDIYLTLTEENDYLVLEEEVPDLVQEDGDL
VFTIVKPVSLAELSDTPRLIFQAMYLGEKAALDAFERAVRNQLSQSFHVV
RSQDNILEILPQGVSKASALKELVEDLGLTADQVMAIGDAPNDIEMLTYA
GLGVAMENASAAIKPLADKVTLTNDMAGVAQAIRQFALAAQKD
>M28_Spy0040 adhA, alcohol dehydrogenase
MKAVVVNQASTGVEVVEHDLPNVGHGEALVKVEYCGVCHTDLHVAHGDFG
QVPGRILGHEGIGIVEEIGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGR
ETLCRSVKNAGYSVDGGMSEYAVVTADYAVKVPEGLDPAQASSITCAGVT
TYKAIKEAGAAPGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKL
ELAKEVGADILVNGKEIEDVPGYIQEKTGGAHGVVVTAVSKVAFNQAIDS
VRAGGTVVAVGLPSEYMELSIVKTVLDGIKVVGSLVGTRKDLEEAFAFGA
EGLVAPVVEKVPVDTAPEVFDEMERGLIQGRKVLDFIS
>M28_Spy0591 amrA, transcriptional activator
MINPSKQNQTIFLWNMLGSLSTAVISVILLMVVTRLLTSADSDIYAFAYS
FANMMVVVGLFQVRNYQATDINEKYSFSQYLVARLMTCLLMLAITVIYLT
LTKTDSYKSTIVFLVCFYRSTDAFSDLYQGMFQQHERLDIAGKSLAYRNT
LIFMVYTAIILYSKNLTLALVAVCIVSLVFIMYYDIGHSKKFQKLMFSEL
LSNISFQNSLKLLKESFPLFLNGFLIIYIYTQPKYAIELMTTLGEVALGS
QTIFNILFMPAFVMNLLILFFRPHITQMAIALIRGQIKEFNKIQVQLFAY
LGVFSLIALVGSGLFGIPFLSILYGTNLTDYWVDFMLIMLGGSIGSFATV
IDNILTAMRKQQLLLIPYTGGFLISLLITNLFVMKYHILGAALSFLITML
VWLGLSIMIYLFIMNRFKKGRVNATIYD
>M28_Spy0221 cbf, CMP-binding factor
MKINQMKKDQLFEGFYLIKSAEVRKTRAGKDFISLTFQDDTGEISGNLWD
AQPYNVEEFTAGKVVFMKGRREVYNGTPQVNQITLRNVRPGEPNDPKDFK
EKAPVSVTEVRDYLEQMLFKIENATWQRIVRALYRKYDKEFYTYPAAKTN
HHAFESGLAYHTATMVRLADSIGDIYPDLNKSLLFAGIMLHDLAKVIELT
GPDNTEYTVRGNLIGHISLINEEITKVISELQIDDTKEEVIVLRHVILSH
HGQLEYGSPVRPRIMEAEIIHMIDNIDANMMMMTTALSRVSEGEMTNRIF
AMDNRSFYKPNY
>M28_Spy1784 cinA, colligrin
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLL
SVITTASQRSDLVILCGGLGPTKDDLTKQTLAKYLRKDLVYDEQACQKLD
DFFAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVL
PGPPSELKPMVNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIE
NQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQLLSRKTLEGQ
PLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPG
ASQVFNGGFVTYSMEEKAKMLGLPLEELKSHGVVSAYTAEGMAEQARLLT
GADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRLDV
RYIATLHAFNMVRKTLLKLENLL
>M28_Spy1141 comEC.1, ComE operon protein 3
MKSQAEAQLFKKEHRWLVMHAKVTLEKAEEVRNFKGFNYQTFLAYQGIYR
IGKVEQIEQLEVISPESICDYLSSLRRRAIVHCQQHFPRPMSHYLTGLLF
GYLDKSFGEMTDYYSQLGIIHLFALSGMQVGFFLTCFRRVLLLLAVPLEW
IKWIELPFACFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACTFLLVF
LWDAHFLMTVGGVLTFSYAFLLTVVTVEELSGAKRQLVQVLTISLGILPF
LLFYFSSFNPMSMVLTGLLSYLFDLFILPLLCLVFCLSPLVTVSICNHLF
ILLEKVIQFLGNTFNSSLVFGSPTSWHLLILVISFAIFYDYRQVRQRVIT
CGLVIALTLLSVKYPLTNEVTFIDIGQGDSILVREWTGKNLLIDVGGRPF
FSSKEHWRRGHHVANAQKTLIPYLKSRGIHTIDQLLVTHADTDHMGDIEV
VAKAIRIKEILTSQGSLSHPSFVRRLRRLKCHVRVLAAGDQLPIMGSVLQ
VLYPWQLGDGKNNDSLVLYGRLLNRTFLFTGDLEKEGENEIIKRYPQLRV
DYLKAGHHGSNTSSSAAFLDHIQPKVAFISAGKNNRYQHPHRETLARLED
RQITYYRTDTQGAIRLTGWTSWHLETVR
>M28_Spy1367 comFC, ComF operon protein 3
MICLLCQQISQTPISITEIIFLRRISSPICQQCQKSFQKIGKSVCATCCA
NSDIIACRDCLKWENKGYNVNHRSLYCYNAAMKAYFSQYKFQGDYLLRKV
FAVELADVITKYYKGYIPVPVPVSPGCFRERQFNQVSAILEAANVSYLSL
FEKLDNTHQSSRTKKERLLVEKSYRLLKVSNIPDKILIVDDIYTTGSTII
ALRKQLAKVANSDIKSLSIAR
>M28_Spy0863 ddh, D-lactate dehydrogenase
MMKLKLYNVRGEEAVLAKKWADDNGIEISLTESPLTPETVKEAEGFDGIA
NAQIGPLDDAIYPLLREMGIKQIAQRSAGVDMYNLDLATENDIIITNVPS
YSPESIAEFTVTIALNLIRHVELIRENVKKQNFTWGLPIRGRVLGDMTVA
IIGTGRIGLATAKIFKGFGCKVVGYDIYQSDAAKAVLDYKESVEEAIKDA
DFVSLHMPPTAENTHLFNADLFKSFKKGAILMNMARGALIETQDLLDALD
AGLLSGAGIDTYEFEGPYIPKNFEGQEITDSLFKALINHPKVIYTPHAAY
YTDEAVKNLVEGALNATVEIIKTGTTTTRVN
>M28_Spy0705 elaC, metal-dependent hydrolase
MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQRQILETT
IKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKT
YVLTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFVVYAERLAHTIFCM
GYRVVQKDLEGTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKD
YISAPKKGKIITIIGDTRKTSASVKLAKDADVLVHESTYGKGDERIARNH
GHSTNMQAAQIAHEAGAKRLLLNHVSARFLGRDCRQMEKDAATIFENVKM
VQDLEEVII
>M28_Spy0376 era, putative GTP-binding protein
MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMGIYTTE
TEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKG
DDMIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPIS
ALEGNNVPTLIKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHL
TQQEVPHSVAVVVESMKRDEETDKVHIRATIMVERDSQKGIIIGKQGAML
KKIGKMARRDIELMLGDKVYLETWVKVKKNWRDKKLDLADFGYNEKEY
>M28_Spy0727 estA, acetyl esterase
MASIAIEYHSVVLGMERKVNVIYPDQSEIPKKDQGDKDIPVLYLLHGMGG
NENSWQKRTAIERLLRHTNLIVVMPSTDLGWYTDTAYGLNYYRALSQELP
QVLAAFFPNMTQKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALD
FSPETLLEGNLGELAYWQGVFGQFDDPDLDKHYLKNMVAESDGKTKFYAW
CGYEDFLFATNEKAIADFQAQGLDIDYHKGHGKHEWYYWNQQLEVLLEWL
PINYQKEERLS
>M28_Spy1481 fabK, enoyl-[acyl-carrier protein] reductase (NADH)
MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGGNAPKEV
VKANIDRVKAITDRPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPG
KYMERLHQAGIIVVPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTT
MSLVRQVVEAVSIPVIAAGGIADGHGAAAAFMLGAEAVQIGTRFVVAKES
NAHQNFKDKILAAKDIDTVISAQVVGHPVRSIKNKLTSAYAKAEKAFLIG
QKTATDIEEMGAGSLRHAVIEGDVVNGSVMAGQIAGLVRKEESCETILKD
IYYGAARVIQNEAKRWQSVSIEK
>M28_Spy1890 guaB, inosine-5'-monophosphate dehydrogenase
MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTLNIPIIT
AAMDTVTGSKMAIAIARAGGLGVIHKNMSITEQAEEVRKVKRSENGVIID
PFFLTPEHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISD
YNAPISEHMTSEHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGL
ITIKDIEKVIEFPHAAKDEFGRLLVAAAVGVTSDTFERAEALFEAGADAI
VIDTAHGHSAGVLRKIAEIRAHFPNRTLIAGNIATAEGARALYDAGVDVV
KVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAREYGKTIIADGGIKYSG
DIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRGMGSIAAMK
KGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
VGAGDIQELHENAQFVEMSGAGLIESHPHDVQITNEAPNYSVH
>M28_Spy0703 hflX, GTP-binding protein
MVKVMIETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMASF
SQKRERYDSKTFIGSGKLDEIKAIVEADEIDAVIVNNRLTARQNANLEAV
LEVKVIDRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGIMLSR
QAGGIGSRGPGESQLELNRRSIRHQIADIERQLTQVEKNRQTIRDRRVGS
DTFKIGLIGYTNAGKSTIMNLLTDDSHYEANELFATLDATTKQLYLENQF
QATLTDTVGFIQDLPTELVAAFKSTLEESKYVDLLLHVIDASDPNHSEQE
KVVLNLLKELDMLNIPRLAIYNKVDIAEQFTATAFPNIRISARSKDSKIL
LRRLIIDQIRDQFVPFRIKVHQDKAYKLYDLNRVALLDHYTFDQEIEDIS
GYISPKQQWRLDDFYE
>M28_Spy1461 hit, bis(5'-nucleosyl)-tetraphosphatase(asymmetrical)
MENCIFCSIIQGDIPSSKVYEDEQVLAFLDISQTTKGHTLVIPKQHVRNL
LEMTAETASHLFARIPKIARAIQLATGATAMNIINNNEALAGQTVFHAHV
HLVPRYNEKDGISIQYTTHEPNFPVLEKLARQINQEVSS
>M28_Spy0306 hlyX, putative hemolysin
MKSLYYFFRSYINMEDPVSQPLVIQFLLLVVLTLLNAFFSASEMALVSLN
RSRVEQKAADGDKKYARLLRVLEEPNHFLSTIQVGITFISLLSGASLSAS
LGKVISGWLGNSATARTAGTIISLVFLTYVSIVLGELYPKRIAMNLKDKL
AIVSAPIIIGLGRLVSPFVWLLSASTNLLSRLTPMTFDDADEQMTRDEIE
YMLSKSEATLDAEEIEMLQGVFSLDEMMAREVMVPRTDAFMIDINDDPLE
NIQEILKQSFSRIPVYDVDKDKIIGLIHTKRLLESGFRQGFDQINMRKML
QEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLEEIV
GEIDDETDKAEQFVHEIGDNTYIVVGTMTLNEFNDYFDTELESDDVDTIA
GFYLTGIGTIPSQEQKEAYEIDNKDKHLVLINDKVKDGRITKLKLILSNI
EQIIEED
>M28_Spy0503 idnO, gluconate 5-dehydrogenase
MENMFSLQGKIALITGASYGIGFEIAKAYAQAGATIVFNDIKQELVDKGV
AAYRELGIEAHGYVCDVTDEAGIQQMVSQIEDEVGVIDILVNNAGIIRRT
PMLEMAAEDFRQVIDIDLNAPFIVSKAVLPSMIAKGHGKIINICSMMSEL
GRETVSAYAAAKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLR
ERQADGSRHPFDQFIIAKTPAARWGTTEDLAGPAVFLASDASNFVNGHIL
YVDGGILAYIGKQP
>M28_Spy1521 isp2, immunogenic secreted protein
MNKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSDSSSKEE
NNKNAAPTTSDKTDQGPLDASAETNSNSLVNADDKKRSDSSQSAVGSSNN
KAEAENQVDDKSTDHSKPTDQPKPTDQPKPSPSKVDTAPASSLSRQLPEA
RTPIQSLSPYVSDLDLSEIDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYG
IKADQIDSYLKSTGIAYDSTRINGEKLLQWEKKSGLDVRAIVAIAMSESS
LGTQGIATLLGANMFGYAAFDLDPTQASKFNDDSAIVKMTQDTIIKNKNS
NFALQDLKAAKFSRGQLNFASDGGVYFTDTTGSGKRRAQIMEDLDKWIDD
HGGTPAIPAELKVQSSASFASVPAGYKLSKSYDVLGYQASSYAWGQCTWY
VYNRAKELGYQFDPFMGNGGDWKYKAGYALSKTPKVGYAISFAPGQAGAD
GTYGHVSIVEDVRKDGSILISESNCIGLGKISYRTFTAQQAEQLTYVIGK
SKN
>M28_Spy1787 lmrP, multidrug resistance protein B
MQEFLNLPKQIQLRQLVRFVTITLGSSIFPFMAMYYTTYFGTFWTGLLMM
ITSLMGFVGTLYGGHLSDALGRKKVIMIGSVGTTLGWFLTILANLPNAAI
PWLTFVGILLVEIASNFYGPAYEAMLIDLTDESNRRFVYTINYWFINIAV
MFGAGLSGLFYDHHFLALLVALLLVNVLCFGVAYYYFDETRPETHAFDHG
KGLLASFQNYRQVFHDRAFVLFTLGAIFSGSIWMQMDNYVPVHLKLYFQP
TAVLGFQVTSSKMLSLMVLTNTLLIVLFMTVVNKLTEKWKLLPQLVVGSL
LFTLGMLLAFTFTQFYAIWLSVVLLTFGEMINVPASQVLRADMMDHSQIG
SYTGFVSMAQPLGAILASLLVSVSHFTGPLGVQCLFVVIALLGIYFTVVS
AKMKKV
>M28_Spy1592 lppC, acid phosphatase
MKSKKVVSVISLTLSLFLVIGCAKVDNNKSVNCKPATKQTYNSYSDDQLR
SRENTMSVLWYQRAAETQALYLQGYQLATDRLKEQLNKPTDKPYSIVLDI
DETVLDNSPYQAKNVLEGTGFTPESWDYWVQKKEAKPVAGAKDFLQFADQ
NGVQIYYISDRSTTQVDATMENLQKEGIPVQGRDHLLFLEKGVKSKESRR
QKVKETTNVTMLFGDNLLDFADFSKKSQEDRTALLSDLQEEFGRRFIIFP
NPMYGSWEGAIYKGEKLDVLKQLEERRKSLKSFK
>M28_Spy0438 mefE, macrolide-efflux protein
MYSKVIYRIGDVMFDFANNTFLAGLNPASLSLVAVYQSLESVIGVLFNLF
GGVIADSFKRKKIIITTNILCGTACLVLSFLTKEQWLVYAIVLTNVILAF
MSAFSSPSYKAFTKEIVKKDSISQLNSLLETTSTVIKVTVPMVAIFLYKL
LGIHGVLLLDGLSFLIAALLISFILPVNDEVVIKEKVTIREIFNDLKIGF
KYVYSHKSIFIITVLSALVNFFLAAYNLLLPYSNQMFGEISTGLYGTFLT
AEAIGGFIGAILSGFVNKELSSMRLILFLSLSGLMLMLAPPFYIMFHNAI
ILALSPALFSLFLSIFNIQFFSLVQKDVDNDFLGRVFGIIFTITILFMPI
GTGFFSVALNPNNSFNLFIIGSCITILSLVFRILFKKYNIR
>M28_Spy0332 metS, methionyl-tRNA synthetase
MMKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGHEVFYLTGL
DEHGQKIQTKAKEAGITPQTYVDNMAKDVKALWQLLDISYDTFIRTTDDY
HEEVVAAVFEKLLAQDDIYLGEYSGWYSVSDEEFFTESQLEEVFRDEDGK
VIGGIAPSGHQVEWVSEESYFLRLSKYADRLVAFFKERPDFIQPDGRMNE
MVKNFIEPGLEDLAVSRTTFTWGVPVPSDPKHVVYVWIDALLNYATALGY
GQANHANFDKFWNGTVFHMVGKDILRFHSIYWPILLMMLDLPMPDRLIAH
GWFVMKDGKMSKSKGNVVYPEMLVERFGLDPLRYYLMRSLPVGSDGTFTP
EDYVGRINYELANDLGNLLNRTVAMINKYFDGTVPAYVDNGTAFDADFSQ
LIDAQLADYHKHMEAVDYPRALEAIWTIIARTNKYIDETAPWVLAKEDGD
KAQLASVMAHLAASLRVVAHVIQPFMMETSAAIMAQLGLAPVSDLSTLAL
ADFPANTKVVAKGTPIFPRLDMEAEIDYIKAQMGDSSAISQEKEWVPEEV
ALKSEKDVITFETFDAVEIRVAEVKEVSKVEGSEKLLRFRVDAGDGQDRQ
ILSGIAKCYPNEQELVGKKLQIVANLKPRKMMKQYISQGMILSAEHGDQL
TVLTVDSSVPNGSIIG
>M28_Spy1180 mutT, mutator protein (7,8-dihydro-8-oxoguanine-triphosphatase)
MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWFLPGGEI
EAGEGQLQALERELIEELGFSATIGSYYGQADEYFYSRHRDTHFYHPAYL
YEVTAFQAVSKPLEDFNNLSWFSPIEAIAKLKRESHQWGVKEWQKKHHST
N
>M28_Spy1563 norA, quinolone resistance norA protein
MLMPFDSNTYIIPLKYIIFCFFCKMFMKIERSSFSMEEKLFNKHFVAITV
INFIVYMVYYLFTVIIAFVATRELGAQTSQAGLATGIYILGTLLARLIFG
KQLEVFGRRLVLRGGAIFYLLTTLAYFYMPTISMMYLVRFLNGFGYGVVS
TATNTIVTAYIPARKRGEGINFYGLSTSLAAAIGPFVGTFMLDNLHIDFR
MVIVLCSVLIGCVVVGAFAFPVKNMSLNAEQLAKTKSWTVDSFIEKKALF
ITAIAFLMGIAYASVLGFQKLYTSEIHLTTVGAYFFVVYALIITITRPAM
GRLMDAKGDKWVLYPSYLFLAMGLFLLGSVSSGGSYLLSGALIGFGYGTF
MSCGQAASIQGVDEHRFNTAMSTYMIGLDLGLGAGPYLLGLIKDLALGSG
VASFRHLFWLAAVIPLICTLLYLLKTKTRQVLS
>M28_Spy0846 nox, NADH oxidase H2O-forming
MSKIVVVGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGCGMALWI
GEQIAGPEGLFYSDKEELESLGAKVYMESPVQSIDYDTKTVTALVDGKNH
VETYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSAD
VIAKLENKDIKRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYY
DRDLTDLMAKNMEEHGIQLAFGETVKEVAGNGKVEKIITDKNEYDVDMVI
LAVGFRPNTTLGNGKIDLFRNGAFLVNKRQETSIPGVYAIGDCATIYDNA
TRDTNYIALASNAVRTGIVAAHNACGTDLEGIGVQGSNGISIYGLHMVST
GLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYDKDSRRILG
AQMAAREDMSMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
ALGAKD
>M28_Spy1069 obg, GTP-binding protein OBG family
MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGGSVIFRV
NEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGAEDLIVFVPQGTTVRDA
ETGKVITDLVEHGQEVVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEE
RQLELELKILADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLG
MVRTKSGDSFAMADLPGLIEGASQGVGLGTQFLRHIERTRVILHVIDMSA
SEGRDPYEDYVSINNELETYNLRLMERPQIIVANKMDMPEAQENLKAFKK
KLAAQYDEFDDLPMIFPISSLAHQGLENLLEATAELLAKTDEFLLYDESD
LVDEEAYYGFAEAEKEFEITRDDDATWVLSGEKLERLFVMTNMERDESIM
KFARQLRGMGVDEALRERGAKDGDLVRIGKFEFEFVD
>M28_Spy0279 pgdA, GTP-binding protein
MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLN
RQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDAD
EYVSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGI
GTGDVLDEIVENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRV
IASPVAGTTRDAIDTHFTDADGQEFTMIDTAGMRKSGKIYENTEKYSVMR
AMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTID
KDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQRLNKLPDLIKRISESQ
NKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKPPTFVVFVN
EEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK
>M28_Spy0567 pheT, phenylalanyl-tRNA synthetase beta chain
MGTKIMLVSYKWLKELVDIDVTPAALAEKMSATSIEVEGIEVPADGLSKL
VVGHVLSCEDVPETHLHLCQVDTGDETPRQIVCGAPNVKAGIKVIVAVPG
ARIADNYKIKKGKIRGMESLGMICSLQELGLSDSIIPKEFSDGIQILPEE
AVPGDAIFKYLDLDDHIIELSITPNRADALSMRGVAHEVAAIYGKSVSFP
QKNLQESDKATSEAIEVAIASDNVLTYASRVVENVKVKPSPQWLQNLLMN
AGIRPINNVVDVTNYVLLYFGQPMHAFDYDKFEDHKIVARAARQGESLVT
LDGEKRDLTTEDLVITVADKPVALAGVMGGQATEIDANSQTVVLEVAVFD
GKSIRKTSGRLNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEGQVL
SGHVQAGQLPTEPVEVSTSLDYVNVRLGTELTFADIQRIFDQLGFGLTGD
ETSFTVAVPRRRWDVSIPADLVEEIARIYGYDKLPTTLPEAGGTAAELTP
TQALRRKVRGLAEGLGLTEIISYALTTPEKAVEFAVAPSHLTELMWPMSV
ERSALRQNMVSGMLDTVAYNVARKQSNLALYEIGKIFEQEANPKEDLPNE
LNHFAFAICGLVAQKDFQTQAQAVDFYHAKGILDTLFANLNLKVQYVPTK
DLASMHPGRTALILLDEQVIGFVGQVHPGTAKAYSIPETYVAELDMAALE
AALPSDQTFAEITKFPAMTRDVALLLDREVSHQAIVTAIESAGVKRLTKI
KLFDVYEGVTIQAGKKSMAYSLTFQNPNDNLTDEEVAKYMEKITKALTEQ
VGAEVR
>M28_Spy1395 recU, recombination protein
MVNYPHNLIRQKVSSVQKQTKQNKVDFANRGMSFEAAINATNDYYLSRQI
AVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYCGVYKGHYVDFE
AKETRQKTAMPMKNFHLHQIEHMACVLHQKGICFVLLHFSTLKETYYLPA
QALISFYQIDNGSKSMPIDYIRKNGFKVAFGAFPQVPYLNIIEQNFLGGD
YN
>M28_Spy1361 recX, regulatory protein
MKITKIEKKKRLYLIELDNDDSLYVTEDTIVRFMLSKDKVLDNDQLEDMK
HFAQLSYGKNLALYFLSFQQRSNKQVADYLRKHEIEEHIIADIITQLQEE
QWIDDTKLADTYIRQNQLNGDKGPQVLKQKLLQKGIASHDIDPILSQTDF
SQLAQKVSQKLFDKYQEKLPPKALKDKITQALLTKGFSYDLAKHSLNHLN
FDQDNQEIEDLLDKELDKQYRKLSRKYDGYTLKQKLYQALYRKGYNSDDI
NCKLRNYL
>M28_Spy0544 sagE, streptolysin S putative self-immunity protein
MPLSIQCLNLCFLLVTFCPSIPMQAIFGKEDSGYAFNLIGFLRATLIYDI
LALVSIYVLSPQITLSLESIDSKTFFMGLVFCVLIVLIELVFLHGLRCWQ
KKQWLPATFSFVGTTNDWSKIGYPLLLALFEETIYRFLWFNILAFQWHLP
TIIVLIVTSFCYALNHLLMGKSIFYAKLVTGIIYGSIYMLTSQLWLVVIM
HVGGNLLVECLSHLQTKKKKGVT
>M28_Spy0017 sibA, secreted protein
MKKRILSAVLVSGVTLGAATTVGAEDLSTKIAKQDSIISNLTTEQKAAQN
QVSALQAQVSSLQSEQDKLTARNTELEALSKRFEQEIKALTSQIVARNEK
LKNQARSAYKNNETSGYINALLNSKSISDVVNRLVAINRAVSANAKLLEQ
QKADKVSLEEKQAANQTAINTIAANMAMAEENQNTLRTQQANLVAATANL
ALQLASATEDKANLVAQKEAAEKAAAEALAQEQAAKVKAQEQAAQQAASV
EAAKSAITPAPQATPAAQSSNAIEPAALTAPAAPSAGPQTSYDSSNTYPV
GQCTWGAKSLAPWAGNNWGNGGQWAYSAQAAGYRTGSTPMVGAIAVWNDG
GYGHVAVVVEVQSASSIRVMESNYSGRQYIADHRGWFNPTGVTFIYPH
>M28_Spy0768 thdF, tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase
MSITKEFDTITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKNLEQVAS
HTINYGHIIDPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNE
ILQLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMTI
AVKQLDGSLSQLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREK
TQEFQSLLENLLRTAKRGKILREGLSTAIIGRPNVGKSSLLNNLLREDKA
IVTDIAGTTRDVIEEYVNIKGVPLKLVDTAGIRETDDLVEQIGVERSKKA
LQEADLVLLVLNASEKLTDQDRALLNLSQGSNRIILLNKTDLEQKIELEQ
LPADLISISVLTNQNINLIEDRINQLFFDNAGLVEQDATYLSNARHISLI
EKAVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQL
FSQFCLGK
>M28_Spy0425 vicX, Zn-dependent hydrolase (beta-lactamase superfamily)
MNESGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLLAEIDRK
PEDLDAILITHEHSDHIKGVGVMARKYHLDIYANEKTWQLMDECNMLGKL
DASQKHIFQRDKVLTFGDVDIESFGVSHDAIDPQFYRIMKDNKSFVMLTD
TGYVSDRMTGIIENADGYLIESNHDIEILRSGSYPWSLKQRILSDLGHLS
NEDGAGAMIRSLGYNTKKIYLGHLSKENNIKELAHMTMVNQLAMADLAVG
TDFTVHDTSPDTACPLTDI
>M28_Spy0160 vlg, Mry
MFLTWENLFLTNQSRRRLKLLVVERSYNNVGNFLKEYFGGFFEIINFDDL
RLTMVDMVSLSSEYDVIVTDMILEQTMDSEILFFNQMAPSVVANRLTDM