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# Streptococcus pyogenes phage 5005.3

>M5005_Spy0261 GTP-binding protein
MEELFCIGCGIQIQTEDKEKAGFTPAAALKKGMETGELYCQRCFRLRHYN
EITDVHITDDEFLRLLHEVGDSDALVVNVIDIFDFNGSIIPGLSRFISGN
DVLLVGNKKDILPKSVKDGKVTQWLTERAHEEGLRPLDVMLTSAQNKYAI
KDLIGRINELRNGRDVYVVGVTNVGKSTLINAIIQEITGNKDVITTSRFP
GTTLDKIEIPLDDGTFIFDTPGIIHRHQMAHYLSPKELKIVSPKKEIKPK
TYQLNPEQTLFLGGLARFDFINGERQGFTAFFDNQLELHRTKLAGADAFY
DKHVGTLLTPPDKKELTAFPKLVRHEFTIDQKMDIVFSGLGWIRVNGQKD
SKAIVAAWAPEGVAVIVRKAII
>M5005_Spy0788 acetyltransferase
MTTEFDKMTRGEWYDANFDSELIQKRMMAQDLCFDLNQLKPSREEERSAV
LNQLFGQSFEGLVLLSPFICDYGKNITFGKNCFINSNCYFMDGAKIALGD
NVFVGPSTGFYTANHPLDYKRRNEGLEKALPITIGDNVWFGANVNVMPGV
TIGSGCVIASGSVVTHDIPVNSLAAGVPCQVVRKIEQE
>M5005_Spy1824 phosphohydrolase
MKDLLKQYQAKPLGEEKRYAVFLPLILVNDDWHVLYEVRSQHISQPGEVS
FPGGQVENQETLQEAAIRETVEELTVDASQIQLWGEIDYLVQSSRTIHCF
VGQLVVDDWKSIQPNEEVDKVFIVPLRQLLFTDPVYYRLEVTPIETTDFP
FDRIRNGKYYQFSQEYRSIPFYENLEETIWGMTAQFTKCLTDILNDESIA
KKNPSDIEKSKGR
>M5005_Spy0601 hypothetical cytosolic protein
MSDTPKYTQDQVIAIKNRILEALETVIDPELGIDVVNLGLIYEIRFNDNG
YTEIDMTLTTMGCPLADLLTDYIHDALQDVPEVTKTEVKLVWYPAWTVDK
MSRYARIALGIR
>M5005_Spy1261 radical SAM family enzyme
MKPSIYSLTRDELIAWAVERGQKQFRATQIWDWLYKKRVQSFEEMTNISK
DFVSILNDSFCVNPLKQRVVQESADGTVKYLFELPDGMLIETVLMRQHYG
HSVCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMLVQKYFDDRKQ
GERVSHVVVMGIGEPFDNYKNVMCFLRVINDDNGLAIGARHITVSTSGLA
HKIRDFANEGVQVNLAVSLHAPNNDLRSSIMRVNRSFPLEKLFSAIEYYI
EKTNRRVTFEYIMLNEVNDSIKQAQELADLTKTIRKLSYVNLIPYNPVSE
HDQYSRSPKERVLAFYDVLKKNGVNCVVRQEHGTDIDAACGQLRSKTMKK
DREKVTATK
>M5005_Spy1387 aldo/keto reductase family
MVTTVKMTSGYEIPVLGFGTYQAADGEEAYQSTLAAIKAGYRHIDTAAIY
KNEESVGRAIKDSGVLREDLFITTKLWNDAHSYEGAKDALAASLDRLGLD
YVDLYLIHWPNPKALRNTWKEANAQAWQYMEEAVEAGLIKSIGVSNFMVH
HLEALQETAKITPAINQIRLAPGCYQKEVVDYCKANEILLEAWSPLGQGE
IFDNETMQQLANKYDKTVAQVALAWSLAEGFIPLPKSVHDERIKENMAIF
DVSLTQEDKKTIRYLSGMSAIPTPDTTSF
>M5005_Spy1248 pyridoxal-5'-phosphate family protein
MDLLTNKKKIFETIRLSTEAANRTNDSVSVIAVTKYVDSTIAGQLIEAGI
EHIAENRVDKFLEKYDALKYMPVKWHLIGTLQRRKVKEVINYVDYFHALD
SVRLALEINKRADHPVKCFLQVNISKEESKHGFNISEIDEAIGEIGKMEK
IQLVGLMTMAPANASKESIITIFRQANQLRKNLQLKKRKNMPFTELSMGM
SNDYPIAIQEGSTFIRIGRAFFH
>M5005_Spy1094 transporter, MFS superfamily
MSTLSLDTTNKRALVAAIAASGTDDLNVMFLAFSMSSIMTDLGLSGTQGG
WIATITNLGMLVGGLLFGLLADRHHKFKVFKWTILLFSVATGLIYFTQSL
PYLYLMRFIAGIGVGGEYGVAIAIMAGIVPPEKMGRMSSLNGIAGQLGSI
SSALLAGWLAPSLGWRGLFLFGLLPILLVIWMTLAIDDQKIWDHYGQEEE
ECSQPIKINELFKTKSLTAQTLALMVMTTVQIAGYFGMMNWLPTIIQTSL
NLSVKSSSLWMVATIVGMCLGMLYFGQLLDCFGPRLIYSLFLLASSICVY
LFQFANSMASMVIGGAIVGFFVNGMFAGYGAMITRLYPHHIRSTANNVIL
NVGRALGGFSSVAIGSILDASGISMVMIFLASLYVISFGAMWSIGQLKAE
RYQQLR
>M5005_Spy0593 neutral zinc metallopeptidase family
MKTDDLRESQQVEDRRGQSSGSFGGGGLGGGLLLQLLFSRGGWKTKLVIL
LLLLVMGGGGLSGVLGGKPSSTNNNAYQSSQVTRTNGDKASQEQVSFVSK
VFASTEDYWTKTFREKGLTYHKPTLVLYTGATQTACGRGQASSGPFYCPG
DQKVYLDISFYNELSTKYGAKGDFAMAYVIAHEVGHHIQNELGIMDNYAS
ARQGKSKAKANQLNVKLELQSDYYAGAWANYVQGQGLLEKGDIEEAMAAA
HAVGDDTLQEETYGRTVPDSFTHGTSKQRQRWFDRGYQYGDFEHGDTFSI
PYSKL
>M5005_Spy0737 mutator mutT protein/7,8-dihydro-8-oxoguanine-triphosphatase
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECA
RREILEETHLTVTEMAFKGIITFPEFTPGHDWYTYVFKVTGFEGDLISDE
ESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRSFFSAKFTYDQNNQL
MDKSVTFY
>M5005_Spy1727 ABC transporter ATP-binding protein
MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGKSTLMNI
IGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTA
CQNVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRV
AIARALVTNPSFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHE
PEVAALCKKTVILRDGNIEHSDIE
>M5005_Spy0301 integral membrane protein
MNDHVIYTQSDVGLNQFFAKIYSLVGMGVGLSAFVSYLMLYPFRENLISI
LVNQPMIYYGAAIIELILVFVASSAARKNTPAALPIFLIYSALNGFTLSF
IIVAYAQTTVFQAFLSSAAVFFAMSIIGVKTKRDMSGLRKAMFAALIGVV
VASLINLFIGSGMMSYVISVISVLIFSGLIASDNQMIKRVYQATNGQVGD
GWAVAMALSLYLDFINLFISLLRIFGRND
>M5005_Spy0571 endonuclease/exonuclease/phosphatase family protein
MINKKCIIPVSLLTLAITLTSVEEVTSRQNLTYANEIVTQRPKRESVISD
KSNFPVISPYLASVDFGERKTPLPTPDKGVKVTTEQSIAQVRKGPEERPY
TVTGKITSVINGWGGYGFYIQDSEGIGLYVYPQKDLGYSKGDIVQLTGTL
TRFKGDLQLQQVTAHKKLELSFPTSVKEAVISELETTTPSTLVKLSHVTV
GELSTDQYNNTSFLVRDDSGKSIVVHIDHRTGVKGADVVTKISQGDLINL
TAILSIVDGQLQLRPFSLEQLEVVKKVTSSNSDASSRNIVKIGEIQGASH
TSPLLKKAVTVEQVVVTYLDDSTHFYVQDLNGDGDLATSDGIRVFAKNAK
VQVGDVLTISGEVEEFFGRGYEERKQTDLTITQIVAKAVTKTGTAQVPSP
LVLGKDRIAPANIIDNDGLRVFDPEEDAIDYWESMEGMLVAVDDAKILGP
MKNKEIYVLPGSSTRPLNNSGGVLLPANSYNTDVIPVLFKKGKQIIKAGD
SYKGRLAGPVSYSYGNYKVFVDDSKNMPSLMDGHLKPEKTNLQKDLSKLS
IASYNIENFSANPSSTKDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPT
DDGTTDATQSAQRLIDAIKKLGGPTYRYVDIAPENNVDGGQPGGNIRTGF
LYQPERVSLSDKPKGGARDALTWVNGELNLSVGRIDPTNAAWKDVRKSLA
AEFIFQGRKVVVVANHLNSKRGDNALYGCVQPVTFKSEQRRHVLANMLAQ
FAKEGAKHQANIVMLGDFNDFEFTKTIQLIEEGDMVNLVSRHDISDRYSY
FHQGNNQTLDNILVSRHLLDHYEFDMVHVNSPFMEAHGRASDHDPLLLQL
SFSKENDKAESSKQSVKAKKTSKGKLLPKTGDSLVYVITLLGTASLLVPI
LLLTKGKKES
>M5005_Spy0266 methyltransferase
MIMEHNYEKFASVYDAVMDDSLYDLWTDFSLRHLPKSKGRNRLLELACGT
GIQSVRFAQAGFDVTGLDLSQDMLAIAKKRAQSAKKKIDFIQGNMLDLSQ
VGQFDFVTCYSDSICYMQDEVDVGDVFKEVYDVLANDGIFIFDVHSTYQT
DECFPGYSYHENADDFAMVWDTYADEAPHSVVHELTFFIQEDDGRFSRFD
EVHEERTYELLTYDILLEQAGFKSFKVYADFEDKEPTKTSKRWFFVAYK
>M5005_Spy0430 ABC transporter permease protein
MAKLRCMHAIFIKQYLKQIMEYKVDFVVGVLGVFLTQGLNLLFLSVLFQH
IPSLEGWTFEQIAFIYGFCLIPKGIDHLFFDNLWALGQRLVRKGEFDKYL
TRPISPLFHVLVETFQVDALGELLVGVILLVTTAGSIVWTLPKVLLFILV
IPFATLIYTSLKIATASISFWTKQSGAVIYIFYMFNDFSKYPMSIYHSFL
RWLISFIIPFAFTAYYPASYFLTGQHLLFNIGGLVVVSLLVLALSLKLWK
WGLDAYESADS
>M5005_Spy0533 hydroxyacylglutathione hydrolase
MKIYKTINHIAGENTYYLVNDQAVILIDPGSNGQEIIAKIKSFEKPLVAI
LLTHTHYDHIFSLDLVRDAFDHPPVYVSEKEAAWLSSPDDNLSGLGRHDD
IITVIARPAENFFKLKQPYQLNGFEFTVLPTSGHSWGGVSFVFHSDELVV
TGDALFRETIGRTDLPTSNFEDLITGIRQELFTLPNHYRVYPGHGPSTTI
CHEKNANPFFH
>M5005_Spy0267 hypothetical cytosolic protein
MTVTGIIAEFNPFHNGHKYLLETAEGLKIIAMSGNFMQRGEPALIDKWIR
SEMALKNGADIVVELPFFVSVQSADYFAQGAIDILCQLGIQQLAFGTENV
IDYQKLIKVYEKKSEQMTAYLSTLEDTFSYPQKTQKMWEIFAGVKFSGQT
PNHILGLSYAKASAGKHIQLCPIKRQGAAYHSKDKNHLLASASAIRQHLN
DWDFISHSVPNAGLLINNPHMSWDHYFSFLKYQILNHSDLTSIFQVNDEL
ASRIKKAIKVSQNIDHLVDTVATKRYTKARVRRILTYILVNAKEPTLPKG
IHILGFTSKGQAHLKKLKKSRPLITRIGAETWDEMTQKADSIYQLGHQDI
PEQSFGRIPIIIKNERLN
>M5005_Spy0514 dGTP triphosphohydrolase
MNEKVFRDPVHNYIHIDNPLIYDLINTKEFQRLRRIKQVPTTAFTFHGAE
HSRFSHCLGVYEIARRVTAIFEEKYADIWNKDESLVTMTAALLHDIGHGA
YSHTFEVLFHTDHEAFTQEIITNPETEINAILVRHAPDFPDKVASVINHT
YPNKQVVQLISSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVED
GIVFEHSGMHAVEDYIVSRFQMYMQVYFHPASRAVELILQNLLKRAQHLY
PEQQAYFQKTAPGLIPFFEKKANLADYIALDDGVMNTYFQVWMASEDHIL
SDLASRFINRKILKSVTFDQDSQGELERLRQLVESVGFDPDYYTGIHINF
DLPYDIYRPELENPRTQIEMMQKDGSLAELSQLSPIVKALTGTTYGDRRF
YFPKEMLELDDLFAPSKETFMSYISNGHFHFSQ
>M5005_Spy0242 ABC transporter ATP-binding protein
MSILEINNLHVSIEGKEILKGVNLTLKTGEVAAIMGPNGTGKSTLSAAIM
GNPNYEVTQGQILLDGVNILDLEVDERARLGLFLAMQYPSEIPGITNAEF
MRAAMNAGKADEDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGE
KKRNEILQLLMLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGKDFGAMI
ITHYQRLLNYITPDLVHVMMDGRIVLSGDAALATRLEKEGYAGIAQDLGI
EYKEES
>M5005_Spy0552 DNA gyrase related protein
MKGMNYQDYIWDLGGTLLDNYELSTQAFVQTLAFFSLPGDHDAVYQKLKE
STAIAVAMFAPNEPEFLHVYRLREADKLAQPIWCLGAKEILGKIATSGSR
NFLISHRDCQVNQLLEQAGLLIYFTEVVTASNGFARKPNPESLFYLKEKY
DINSGLVIGDRLIDKQAGQAAGFNTLLVDGRKNLLEIVT
>M5005_Spy0486 hypothetical protein
MDLVGISLMIIALAFVALVIFLIIVLKKVSETIDEAKKTISVLTSDVNVT
LHQTNDILAKANILVEDVNGKVATIDPLFVAIADLSESLSDLNSQARHFG
QKATNATGNVSKAGKLALVGKVASKVFGKKGEKHE
>M5005_Spy0209 jag protein
MVLFTGKTVEEAIETGLQELGLSRLKAHIKVISKEKKGFLGFGKKPAQVD
IEGISDKTVYKADKKATRGVPEDINRQNTPAVNSADVEPEEIKATQRLEA
EDTKVVPLMSEDSPAQTPSNLAETVTETKAQQPSIPVEESEVPQDAGNDG
FSKDIEKAAQEVSDYVTKIIYEMDIEATVETSNNRRQINLQIETPEAGRV
IGYHGKVLKSLQLLAQNFLHDRYSKNFSVSLNVHDYVEHRTETLIDFTQK
VAKRVLESGQDYTMDPMSNSERKIVHKTVSSIEGVDSYSEGNDPNRYVVV
SLQR
>M5005_Spy0692 GTP-binding protein
MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSSFINTIL
GRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGK
MIEEYLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKA
DKIPRGKWNKHESVVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV
>M5005_Spy0841 glutamine amidotransferase, class I
MTKPIIGITANQRLNMALDNLPWSYAPTGFVQAVTQSGGLPLLLPIGDEA
AAKTYVSMVDKIILIGGQNVDPKYYQEEKAAFDDDFSPERDTFELAIIKE
AITLKKPILGICRGTQLMNVALGGNLNQHIDSHWQEAPSDFLSHEMIIEP
DSILYPIYGHKTLINSFHRQSLKTVAKDLKVIARDPRDGTIEAVISTNDA
IPFLGVQWHPELLQGVRDEDLQLFRLFVNDF
>M5005_Spy0745 ABC transporter permease protein
MIISSVSQGLIWGVLGLGIYLTFRILNFPDMTTEGSFPLGGAVAVTAISL
GWNPFLSTLLGMLSGALAGFLTGLLYTKGKMPTLLAGILVMTSCNSIMLM
VMGRANLGLHDHKRIQDCLPFSIDLNSLLTGLITVVIVISVLIYFLYTNL
GQAYIATGDNKDMAKSFGINTDWMEVMGLVVSNSLIALSGALVSQQDGYA
DVSKGIGVIVIGLASIIVGEVLYSTGLTLLERLIAIVIGSILYQFLISVV
ITLGFNTSYLKLISALVLALCLMIPVVKERFFKGVRLTR
>M5005_Spy0360 NAD-dependent oxidoreductase
MSQTVKGDEQMKLAVLGTGMIVKEVLPVLQKIDGIDLVAILSTVRSLTTA
KDLAKAHHMPLATSKYEAILGNEEIDTVYIGLPNHLHFAYAKEALLAGKH
VICEKPFTMTAGELDELVVIARKRKLILLEAITNQYLSNMTFIKEHLDQL
GDIKIVECNYSQYSSRYDAFKRGDIAPAFNPKMGGGALRDLNIYNIHFVV
GLFGRPKTVQYLANVEKGIDTSGMLVMDYEQFKVVCIGAKDCTAEIKSTI
QGNKGSLAVLGATNTLPQVQLSLHGHEPQVINHNKHDHRMYEEFVAFRDM
IDQRDFEKVNQALEHSRAVMAVLERAVHS
>M5005_Spy0739 tetratricopeptide repeat family protein
MLNSEKMIASLDQQDLAHAEKYFQKALKEDDADSLIALGEYLESIGFLPH
AKRIYLQLADDYPELNINLAQIAAEDDAIEEAFLYLDKVSKDSPNYLSAL
LVMADLYDMEGLTEVAREKLLQAVGISPEPLVIFGLAEIDMSLQHFKEAI
DYYAQLDNRQILELTGISTYQRIGRAYASLGKFEAAIEFLEKAVAIEYED
ETVFELATLMYDQENYQKANLYFKQLETINPDYPGYEYGYALSLHEEHKT
SEALRLVQQGLRKNAFDSQLLLLASQLSYELHDRQNAENYLLQAKEVAVD
DEEILMRLVTLYFDAERFEEVIALNRETIDNVLTKWTIAKAYHALEQEEV
ALALYNEISADLAENPEFLQDYAYLLREFGQFHKAIQMATAYLRQVPDDV
NMQDFLDHIKHQQSE
>M5005_Spy0839 hypothetical membrane spanning protein
MKFEKKQVFYLVLTFILCYGILANWRNGTAIVTTIYKTSLPFFYGAAGAY
IVNIVMSAYEKVYVYIFKDWSHVLKVKRGICLLLAYLTFFILITWIISIV
IPDLITSISTLTKFDTITIQEVVNNLEHNKLLARTIQYIGGDGKLTETIA
NYSQQLLKQFLTVLTNILTSVTVIASAIINLFISFVFSLYVLASKEDLCR
QGNTLVDTYTGKYAKRIHYLLELLHQRFHGFFVSQTLEAMILGSLTASGM
FILRLPFAGTIGVLVAFTALIPVIGASIGAAIGFILIMTQSMSQAIIFII
FLIILQQIEGNFIYPKVVGGSIGLPAMWVLMAITIGASLKGIVGMIIAVP
LAATLYQVIKDNIQKRQAIQKKQVS
>M5005_Spy0861 4-oxalocrotonate tautomerase
MPFVTIDLFEGRSQEQKNQLAREVTEVVSRIAKAPKENIHVFINDMPEGT
YYPQGEMKQKS
>M5005_Spy1378 NADH peroxidase
MTLTTKTIHVIGASFAGLAFVDKYKDLNPDSQIILIDKESCPNYIPNGIN
QLFRGDIQDLSDAMWGRACLAAQIESNHRFIQAEVLAIEAPSNTLLLKDS
QGRVFEEGYETLVCAMGASPQSHYIETSQTNKVLVTKYYEESQASLKLIE
ASQEVLVIGAGLIGLDLAYSLSLQGKRVKLIEAAERPDFYQTDAELIAPV
MAEMSTHHVTFINNKRVTAIHEIEGKVVAHTEQGDTFQGDLAILAINFRP
NTHLLQGQVACALDKTILVNENLQTSQANIYAIGDMVSLHFGILGMDYYT
PLINQAMKTGQALALHLAGYPIPPLQTVKVLGSSHFDYYRASVGVTEEEA
ELYMDTCSYLYQNGDSKNLFWLKLIARKTDGILIGAQLLSKTNALVIANQ
LGQALALKVTDADLAFQDFLFLQGHSDLAYHLHEACLKLFEKRLRHED
>M5005_Spy0658 regulatory protein
MTTTDKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPNMAAAEF
LHIVQVFQFFTPIMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVI
QKGVATGTFQLRGIGDLINMMITASLAVLAVKYFGNKFGSLTIILLPITI
GTGVGYIGWKFLPYVSYVTTLIGQGINSFTTLQPILMSILIAVAFSLIIV
SPISTVAIGLAIGLNGMAAGAASMGIASTAAVLVWATLKVNKSGVPIAIA
LGAMKMMMPNFLKHPIMAIPMVFTAAISSLTVPLFNLVGTPASSGFGLVG
AVGPIASLAGGSSILIIILAWIIVPFAVAFAAHKVSKDILKLYKEDIFVF
EG
>M5005_Spy0080 bis(5'-nucleosyl)-tetraphosphatase(asymmetrical)
MTECIFCHQLKANQLLTQSQYFKVVFDIDPIQKGHLLLISKDHYTSLTQL
PKEGHYDLIDLQAALVAKLEQHLPISGVTSVSNDKELMDEGTHFHLHLIP
RLTNDSFWEGITINQENWDLTPFLKHL
>M5005_Spy0359 short chain dehydrogenase
MRSMTKVVLVTGCASGIGYAQARYFLKQGHHVYGVDKSDKPDLSGNFHFI
KLDLSSELAPLFKVVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINF
FATVKLTRHYLRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGF
TRQLALDYAKDQIHIFGIAPGAVKTAMTANDFEPGGLADWVARETPIGRW
TKPDEVAELTGFLASGKARSMQGEIVKIDGGWTLK
>M5005_Spy0411 multidrug resistance protein B
MNWRQNLKVAWLGNFFTGASFSLVMPFMALYVENLGTPTELVEYYAGLAV
AVTALASALFAPVWGKLADRYGRKPMMLRASFVMTFTMGGLAIIPNVFWL
LILRLLTGVFAGYVPNATALIASQAPKEESGYALGTLATGVTAGALIGPL
LGGILAELLGIRQVFLLVGVILFLCSLMTAVYVKEEFKPVRRFEMIPTKV
ILKQVKSPQIMLGLFVTSMIIQISAQSVAPILSLYIRHLGQTHNLMFTSG
LVVSAMGFSSLFSSSYLGKLGDRFGNHRLLLAALCYSFIMYFSSALAQTS
FQLGVLRFAYGFGVGALMPSINSLLTKLTPKEGISRVFAYNQMFSNLGQV
IGPFIGSNVAVVLGYRSVFYVTSLIVFVNLIWSLIIFRKYIKVKDIV
>M5005_Spy0487 hypothetical exported protein
MNKSFKNLVIGAVSGVAAAYFLSTEKGKALKNRAEKAYQAYKESPDDYHQ
FAKEKGSEYSHLARDTFYDVKDKLASGDLTKEDMLDLLKDKTTAFVQKTK
ETLAEVEAKEKQDDVIIDLNEEDIIIDYTEQDEPVSDTLDKH
>M5005_Spy1465 phage protein
MMTPETVCQEKGIDLVYFDGRGTNTPGMFNKKHNVIAIDTYLDGIYKHKV
IYHELGHREHTASYYKLNKEKAELQADRCMIHHLLKEELSYWDNMEDFNY
IQFMEKYELTSIADEVMIKEELEFLIS
>M5005_Spy0156 metal-dependent hydrolase
MTKVQDITRESWILNTFPEWGTWLNEEIEQEVVPADNFAMWWLGNCGIWI
KTPGGANVVMDLWSNRGKATKQVKDMVRGHQMANMAGARKLQPNLRAQPM
VIDPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLNHVKFVGPYECGE
VWKNWGVPKDRIMILKPGDSFEFKDIKITAVESFDRTCLVTLPIQGADAQ
DGDLAGLAITDDDMARKAVNYIFETPGGTIYHGADSHFSNYFAKHGRDYD
IDVVLNNYGENPIGIQDKMTSVDLLRMAENLRAKVVIPVHYDIWSNFMAS
TDEILELWKMRKERLQYDFHPFIWEVGGKYTYPQDQNRIEYHHPRGFDDC
FLEDSNIQFKALL
>M5005_Spy0163 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase
MKKYLNQNVYDALIERLHFLFNEFPIVYISFSGGKDSGLLLNILLDFRDK
YYPDREIGVFHQDFEAQYSLTTKYVQETFTSLEGRKKVSLYWVCLPMATR
TALSSYEMFWYPWDDKTEDIWVRPMPSQDYVINLENNSITTYRYKMNQED
LAKQFGRWYKQIHGNQKTVCILGNRASESLHRYSGFINKKYGYQKECWIT
KQFKDVWTASPLYDWSVEDIWHAYYKFSYSYNELYDLFYKAGLKPSQMRV
ASPFQDYAVDSLNLYRIIDQETWVKLLGRVQGVNFSNIYGRTKAMGYKSI
ALPKGHSWKSYTQFLLSTLPVRLRNNYVRKFNKSIDFWHKTGGGLAEETI
NELIEKGYRIARNGISNYTSFKHSRVIFLDQIPDDTDDIVTTKDIPSWKR
MCFCILKNDHICRTMGFGLTREQQKIVAFLKEKYKTSLKELESE
>M5005_Spy0623 methyltransferase
MNKLYIDSFVEKKLTAGVQLLDEKDFSNIKEKNQLVQLVTKSNRPIGTAY
ISKQNKGIGWYLGPEKIDLSISYFVSLFSVAKAKRQDFAQSDETNAYRLF
NQEGDGFGGVTIDLYKDFAVFSWYNAFVYDKKEMIMEAFQQVFPEVKGAY
EKCRFKGPDTETAHLYGELAQETFSILENGIAYQVFLNEGLMTGIFLDQH
DVRRALVDGLAMGKSLLNLFSYTAAFSVAAAMGGAIETTSVDLAKRSREL
SLAHFEHNQLNLASHHFVVMDVFEYFKYAKRKKLIFDVIVIDPPSFARNK
KQTFSVSRDYHKLITEALDILSPKGTIIASTNAANMTVSQFKKQIIKGFG
SRRPESMTLQQLPSDFTINKADERSNYLKVFTIKVRE
>M5005_Spy0866 phosphinothricin N-acetyltransferase
MLRPLSKTDCPMLQEINAKALGYLVSLDLLERQYERLIEDCHHYFLAYAD
KDTNQLLGYVHAERYETLYASDGLNLLGLAVLPAYQRRGIGSALLRALES
QARQEGIAFIRLNSASHRKEAHAFYRNLDYADDKTQLRFIKNLQGDDNDF
>M5005_Spy0535 acetoin dehydrogenase
MEQFAKDITLKRLSEPEDIANAVGFLAGDDSNYITGQTIVVDGGMVFH
>M5005_Spy0281 hypothetical cytosolic protein
MLAISEIRKHPDGLSFDRLCDVKSMLLERDQQIIDIKAVKAVGNVRYDKG
LYLLDYQLSYEVILPSSRSMVPVCLSEVQHIQELFIEATDLADKKELVED
NLVLVLDKDAINLEESIVDNILLAIPLQVLTEEEKKSKELPAGQNWAVLT
EEDYQCLKEEKQKENNPFASLQGLFDE
>M5005_Spy1476 ATP/GTP hydrolase
MFYSENEYTLKAYGETLGTYLSIGDVIVLSGDLGAGKTTLAKGIAKGMGI
SQMIKSPTYTIVREYEGRLPLYHLDIYRVGDDPDSIDLDDFLFGNGVTVI
EWGELLGEGLLQDYLQITITKRDKGRQLDLLAHGERSRQLLEIMSHGSAK
SRY
>M5005_Spy1779 transcriptional regulator, LuxR family
MTKGIRFQLLGSPHIFLDDKEQFFAFAKANALLYYLVVNGSVSREVAASL
LWENKNTQTAKKNLRNAIYQVNKVLQADVIICPNRNLLVLNKTLDIKTDI
NLFLADPLAHLELYQGEFLQGFYLKSGEEFDLWVSKMRMQYEQVYLKACY
QKIEEKLSLDAIEDVEEHLKQLIERDEFEEKNYQLLMRLYQQGNCPGKVI
ETYYQLANVLDKELGIQPSLQSQQIYQEVVAKDRNERKIKHFLRNSNHFL
GRIDEIKQLENYFANCLACQEVGALLLIGDTGIGKRTLARQVLANQTQTF
QIVTAKCFREEAMDSLLPWRNILDGLGDLVIQNRLLTTKAWKAALKRCFP
VATIFQEDNNQPFIKDHTSLLVSFIVDILQHLAEIKALVILIEDCHWMDE
DSLTLLQRVMNQLVHYPIAFVLTKHLGTTPELGLCLNALMSQGRLESICL
EPFNRQESLVYINSQLGSQPVTAEEMEHLYQASQGNPFFLSEYTQALLRH
EKFVPLTPAIKAKLGLKLANLSSRDDALLNYLSCCRRPIPLNTLAQLMLL
PLEEVIEMVDNLGHYYILVEESVGEEVLISFRQRIIQLYSYDRLSLSKRR
LLHGQIAKRLEDLLPILTPSPHLLDDIAYHYQESRQVIKALEYNLNYLDA
TLPFQHELFPIYSKSIGSLEKSDRDHQRLMEEQFDKIRQSIADLELTYDN
NRDFQQLLIRFSYLEGRYDIRTGRYQEGIKHIQKVIALATELKQPSFLLE
GYRQLIHYCIQVENKPEMRYYTSLSLEAAVAANHFEAIAISLRLNGLYHL
IIGELNEAERLLQQSIDFFKVTPGLQANYAIQIAAALDYLGEIAQIRYQF
EKAVAYQKQAIALTENKPAELSASIFYIGLGISYFYLADFEQAEQILSLA
KEALVNHSYPWKETQLEIYLAMIQWKKGNYQPALTLLDYRETLMSRYRNP
RDKGLVFYLMAVVKYQLIFQGATLSQQEKEMADHLLSESFEYYYEIASTN
LNPYRDCHLVSELNDLRQQLSAKS
>M5005_Spy1691 exodeoxyribonuclease III
MTKVLTLNTHSWMQANTLKKLVALAEHILAEKYDIICLQEINQLIESELA
TDLPRYQALSGTPSIHKDHFALLLIHYLQKRGQHYYWSWAYNHIGYDIYQ
EGVAILSKQPIHVSDILVSAMDDETDYHTRRSLIAKTTLDGKEVAVVNVH
LSWFDKGFLGEWEKLEKELLTLNCPLLLMGDFNNPTDQDGYQVMMGSPLD
LQDSHKGADHVFGDHSIVADIDGWQGNKEALKVDHVFTSKDFIIRSSKIT
FEGGDAPVVSDHYGLEVTLGWR
>M5005_Spy0539 ATP-binding protein
MSDKHINLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALVPKFLELIE
QTNENRRVALVVDMRSRLFFKEINSTLDSIESNPSIDFRILFLDATDGEL
VSRYKETRRSHPLAADGRVLDGIRLERELLSPLKSMSQHVVDTTKLTPRQ
LRKTISDQFSEGSNQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQ
VELREKTGLDEDVFNYVMSHPESEVFYKHLLNLIVPILPAYQKEGKSVLT
VAIGCTGGQHRSVAFAHCLAESLATDWSVNESHRDQNRRKETVNRS
>M5005_Spy1163 transcriptional regulator, biotin repressor family
MKAEDRRQKIIECLNSEQKAVSATRLGKLLGVSRQVIVGDIALLRAQQID
IISTPKGYIMSTALYSHQFCARIVCQHNVEETKKELEIILAHQGIITTVE
VEHPIYGMITAPLNIKTHSDVTNFMSKLSQSKAELLSSLTEGLHSHLISC
PSQEAFLAIKHDLELAGILYKGI
>M5005_Spy0731 para-aminobenzoate synthase component I/anthranilate synthase component I
MDSQLSNRLAQVAAYVPKGVKLLDVGSDHAYLPIFLVETNQISAAIAGEV
VRGPYESALKNVTQSGLAEHIQVRLANGLAAFEEADDVTAITICGMGGRL
IADILEAGKEKLQALNVWFYNPTIVRMIYGLGYRLTLLKLLQKPSWLKMT
NIMKSSLLSMVKRPYPRQNCVLVHTFLRKNQSFLKRSGNEKWIS
>M5005_Spy1592 ribosomal-protein-alanine acetyltransferase
MIVTTLSESNMKTVEEQAKNIYQLLEMVYGTSPWTLEQVLIDIRRDQTDY
FLLYDHDKLLGFLAIQDLAGEVEMTQIAILPSHQELGLASQLMTHLDSIE
SDIFLEVRESNHRAQGLYQKFGFKFIGKRPDYYRNPIETALLMKREGKHD
R
>M5005_Spy0942 nucleoside-binding protein
MNKKFIGLGLASVAVLSLAACGNRGASKGGASGKTDLKVAMVTDTGGVDD
KSFNQSAWEGLQSWGKEMGLQKGTGFDYFQSTSESEYATNLDTAVSGGYQ
LIYGIGFALKDAIAKAAGDNEGVKFVIIDDIIEGKDNVASVTFADHEAAY
LAGIAAAKTTKTKTVGFVGGMEGTVITRFEKGFEAGVKSVDDTIQVKVDY
AGSFGDAAKGKTIAAAQYAAGADVIYQAAGGTGAGVFNEAKAINEKRSEA
DKVWVIGVDRDQKDEGKYTSKDGKEANFVLASSIKEVGKAVQLINKQVAD
KKFPGGKTTVYGLKDGGVEIATTNVSKEAVKAIKEAKAKIKSGDIKVPEK
>M5005_Spy1517 lantibiotic transport permease protein
MISYLKADLFRIRQERLALFSCMLLVVIAVGVAYSFRKTPNQVIMIQIIN
IITDFVTLFFLTPARIFFSDDYNYRTINNVVVKQQNRTLIIIYKLLVSFG
LSLLFISLTYLLSALAFHLFTGQAYYGIVIDRMIKQLPFYIAIIALCQFL
FNILRKTYQSITAYILYVLLFDKVSATLANHFFKLDISPVLMFKHLSLSL
GDKHLSSTSILVAFGLTLCYLLGNVFLFSKRELK
>M5005_Spy1150 methyltransferase
MIKAILKEGERIDQLFSSDVGIIQNKDVFSYSIDSVLLSRFPKMPSKGLI
VDLCSGNGAVGLFASTRTKAAIVEVELQERLADMGQRSIQLNQLEDQVTM
ICDDLKNLLNHVPRSGVDLMLCNPPYFKSHESSKKNVSEHYLLARHEVTT
NLEEICQVARHALKSNGRLAMVHRPDRFLEIIDSLRANGLAPKRVQFVYP
KLGKSANMLLIEAIKDGSIEGMTILPPLVVHKENGEYTDHIFEIYFGAAS
KGKPNHDH
>M5005_Spy1274 acetyltransferase
MADKFDANDETRTVYAVVYDNDQPVSTGQFLAETKIEARLTRIVTLADYC
GCGYGAKVTEALETYTRREGFYQLTIHSELTAQTFYENLGYQSYGPKCLE
DGEYCQSLAKTILKWEKNMDIAMLIAIVGGLLGCYLYLTKNN
>M5005_Spy0939 nucleoside transport system permease protein
MSLVTIFALLMSSMLIYATPLIFTSIGGTFSERSGVVNVGLEGIMVMGAF
SGIVFNLEFAETFGKATPWIAVLVGGIVGLIFSLIHAVATINFRADHIVS
GTVLNLLAPSFAVFLVKAMYGKGQTDNIQQSFGKFDFPGLSQIPVIGDIF
FKNTSLIGYFAIAFSFFAWFLLYKTRFGLRLRSVGEHPQAADTLGINVYL
MKYYGVMISGFLGGIGGAVYAQSISVNFAVTTILGPGFIALAAMIFGKWN
PVGAMLSSLFFGLSQSLAVIGAQLPLLEKIPTVYLQIAPYMVTIIILAAF
FGQAVAPKADGINYIKSK
>M5005_Spy0743 ABC transporter substrate-binding protein
MKNKSLIATLLVLTVIVIGSLLSKGVSKENRDLANQQNITIGILQFVTHE
ALDDIKRGIEDQLKKQMPQKQNVVIKVMNAEGDQSKIQTMSRQLVQSGSD
IVIGIATPAAQGLAATSKDIPVVMSAVSDPVGSRLVMQLDQPEANVTGLS
NKVPVKQTIDLMKKLTPHVKTVGILYASNEDNSLSQVKEFRRLARKKGYQ
VISYAVPSTNEVPATMSVMLGKVDAVFIPQDNTIASAFSSVMTTSKAAKI
PVYTSVDRMVEKGGLAAISQNQYDLGVQTANQVLKLIKGKRVVDVPVKVV
DIGQPLINKNVAAELGIAIKKEDFPSASFIEN
>M5005_Spy0547 phosphoesterase, DHH family protein
MITTFETILDKIKAHQTIIIHRHQNPDPDALGSQAGLKEIIAQNFPDKKV
LMTGFDEPSLAWISQMDQVTDKDYKEALVIITDTANRPRIDDERYTLGKC
LIKIDHHPNDDVYGDFYYVDTSASSASEIIADFAFSQNLTLSDKAAKLLY
TGIVGDTGRFLYASTTSKTLSIASQLRHFEFDFAAISRQMDSFPLKIAKL
QSYVFEHLTIDESGAAYVLVSQETLKHFDVTLAESSAIVCAPGKIDNVQA
WAIFVELTDGNYRVRMRSKEKIINGIAKRHGGGGHPLASGANSANLEENQ
AIFRELIAVCQEI
>M5005_Spy0738 hypothetical membrane spanning protein
MPLIPEKSRTDSLFYKWFLNNQATMALVITLLAFLTIFVFTKISFLFMPV
ISFFAVIMLPLVISTILYYLTKPLVDLINHLGPNRTTSIFIVFGLITLLF
VWAISGFVPMVQTQLTSFIEDLPKYVGKVNEEANKLLENEWLVSYKPQLQ
DMLTHTSQKALDYAQSFSKNAIDWAGNFAGAIARITVAIIISPFILFYFL
RDSSHMKNGLVNVLPLKLRVPMVRVLGDINKQLSGYVQGQVTVAIVVGFM
FSIMFSLVGLKYAITFGIIAGFLNMIPYLGSFLAMIPVVIMAMVQGPFML
VKVLVIFMIEQTIEGRFVAPLVLGNKLSIHPITIMFLLLTAGSMFGVWGV
FLVIPIYASVKVVIKELFDWYKKVSGLYDEEVLVIEEVKDHVK
>M5005_Spy0101 tRNA binding domain protein
MIFAYNKEQVGDVLMVILQDTKDIKRQVERKGKVARVFAEESGKTLAWNI
FEASSLITIEGNGQIFLTDENLARLNAELAKEGFSERLEPIVGPVFVVGQ
IVEMVAHPDSDHLNICQVAIGEDQTVQIVAGAPNAALGLKTIVALPGAIM
PNGSLIFPGKLRGEESYGMMCSPRELALPNAPQKRGIIEFDESAVVGEAF
DPAKHWKG
>M5005_Spy0512 hydrolase, HAD superfamily
MSIKLVAVDIDGTLLTDDRRITDDVFQAVQEAKAQGVHVVIATGRPIAGV
ISLLEQLELNHKGNHVITFNGGLVQDAETGEEIVKELMTYDDYLETEFLS
RKLGVHMHAITKEGIYTANRNIGKYTVHESTLVNMPIFYRTPEEMTNKEI
IKMMMIDEPDLLDAAIKQIPQHFFDKYTIVKSTPFYLEFMPKTVSKGNAI
KHLAKKLGLDMSQTMAIGDAENDRAMLEVVANPVVMENGVPELKKIAKYI
TKSNNDSGVAHAIRKWVLN
>M5005_Spy1440 terminase large subunit
MTIKQRPKINIVIKYPSKVFNKHIYDKLYNYSNFTEVHYGGASSGKSHGV
FQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGILDKC
KINMSAFRITLPNGSEFIFKGMDNPEKIKSIKGISDVVMEEASEFTLDDY
TQLTLRLRDKKHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQTTYK
DNRFLDDVTRENIEELADRNEAYYKIYALGQFATLDKLIFPKYDKQILNK
DKLSHLSSFFGLDYGFINDPSAFLHVKIDDANKKLYVIEEYVRKNLTNDK
IANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIPRMIDVTKGPGTVMQGI
QYLLQYDWVVDERCVKTIEELENYTWKKDKKTNEYINEPVDSYNHCIDAI
RYAVQDRIYQSADRSKRMKNAKYYF
>M5005_Spy0160 CoA binding protein
MIYSFQNPSEDILKAYLESAKTIAVVGLSDRKDTAAYGVAKFMQAMDYRI
IPVNPKLAGQLILGEKVYASIKAIPFEVDIVDVFRRSEFLPEVARDFLAG
QAKVFWAQLGLENQEVQTILRSAGKEAIVMNRCLKIDYLQLVAKPECITN
L
>M5005_Spy1477 guanine-hypoxanthine permease
MEKFFKLSENGTTVSTEIMAGLTTFFAMSYILFVNPSILGAAGMPSNAVF
LATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFALGFSWQEAL
AMVFICGLFNIFITVTKFRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNA
NIITFSISAENIVMVNGVEPAKASAKTFADGLLFVDANGGVVPTISSFTD
SGVLLAIFGLLLTTALVIRNFRGAILIGIVATTLVGIPLGIVDVSNLNFG
ISHIGEAWTELGTTFLAAFDGLSSLFSDSSRLPLVFMTIFAFSLSDTFDT
IGTFIGTGRRTGIFSQDDENALENSIGFSSKMDRALFADAIGTSIGALVG
TSNTTTYVESAAGIAEGGRTGLTAVSTAVCFLLSILLLPLVGIVPAAATA
PALIIVGVMMVSSFLDVNWSKFADALPAFFAAFFMALCYSISYGIAAAFI
FYCLVKVVEGKTKDIHPIIWGATFLFIVNFIILTIL
>M5005_Spy0471 hydrolase, HAD superfamily
MNIRILALDLDGTLYNTEKIVTDANKKALAAAREKGVKVVITTGRPLKAI
GNLLEELDLLDHDDYSITFNGGLVQRNTGEVLDKSSLSFDQVCQIQQALE
AVGLPTDIISGGDVYSIPSKDGRHSQYHLANPLLTFIEVTSVAELPKDIT
YNKIVTVTDPDFLDQQIIKLSPSLFEDFEAFKSRDIIFEIMPKGIDKAFG
LNLLCQHLGLDARHVMAMGDEANDFAMLEWAGLGVAMANGVSGAKADADA
VTTLTNDESGVAEAVKTFILEEES
>M5005_Spy1515 hydrolase, HAD superfamily
MVGLATGRGPGFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSMI
YKVIRYANEKKREISLGTASGLAGSRIIDMGTSPFGQVISSFVPKSWART
VEGSFKHLIRRIKPQSFRNLVTIMREPIYQVVLVASQAETKKIQEKFPHI
KITRSSPYSLDLISVDQSKIKGIERLGEMFGFDLSEVMAFGDSDNDLEML
SGVGIGIAMGNAETVVKDGAHFTTDSNNNDGISKALAHYGLIHFDIEKSF
KSRDENFNKVKDFHRLMDSDTIETPRSYTISEAGYRSGFKVEEIVEFLYA
ASKGDQQQFTQAIFDLHGAVDQAANKVQAKKHVETPLIGQVDALADLLYF
TYGSFVLMGVDPQPIFEAVHEANMAKIFPDGKAHFDPVTHKIQKPDYWQE
RHAPEVAIKKELDKQLQKSLQRFDK
>M5005_Spy0889 regulatory protein (pfoS/R)
MIGQGIASLLGLQPILMSLLIAMIFCFLIVSPITTVGIALAINLSGIGSG
AASFGLCLAGWAVNSKGTSLAHVLRSPKISMANVLSKPKIMLPMLCSAAV
LGVIGAIFNIQGTPASAGFGISGLIGPINALNLAKGGWCPVNILLIIIIF
VGAPIVLNMIFNYLFIKVLKVIDPMDYKLDI
>M5005_Spy1475 acetyltransferase
MVQQSLVIEEGVPQDAKAVLSLVTAAAKETDFITGVETILEATPQELSDF
LSRSQTSFIDFCLLARLDEKVVGLLNLSGEVLSQGQAEADVFMLVAKTYR
GYGIGQLLLEIALDWAEENPYIESLKLDVQVRNTKAIYLYKKYGFRIESM
RKNDIKSKNGDDLDVYHMRKSVSQ
>M5005_Spy0291 acetyltransferase, GNAT family
MLIRQVQGSDLEVIATIESDNFSPQEATTRAVLEEHIRLIPDTFLVALID
QEIVGYIEGPVVTTPILEDSLFHGVTKNPKTGGYIAITSLSIAKHFQQQG
VGTALLAALKDLVVAQQRTGLILTCHDYLISYYEMNGFINQGISESQHGG
TLWYQMIWKL
>M5005_Spy0473 multidrug resistance protein B
MSHHQQTVSKQTIMAIIAIALIGFSGILSETSMNVTFPTLMSVYQLPLNS
LQWMTTIYLLAVAIMMTTSATLKKNVRERPLFFMATGLFTFGTILAVLTQ
SFAIMLLARIFQGIGTGLVMPQMFNIILERVPMHKVGLFMGFAGLIISLA
PAFGPTYGGFMISHFSWQWIFICILPVPLIAGILAYYYLEDSPVSEKVPF
DWLAFIALSISLTSALLAITSLENGSVNLYYLGLFILSFILFLYKNLTAK
QPFLDIRILKIPSLTFGLIPFFVFQLINLGINFLTPNFIVMEKIANSSQA
GMVLLPGTLLGALLAPAFGKLYDQKGARLSLYLGNALFSLSLIIMTLQTR
HFMLLPFTLLYILFTFGRNMGFNNSLATAIRELPAEKNADATAIFQMMQQ
FAGALGTAMASLIANSQAEFTSGVQSVYLLFTIFALLDFIFFFAMFYHLG
KKGLA
>M5005_Spy0028 autolysin
MKKFHRFLVSGVILLGFNGLVPTMPSTLISQQENLVHAAVLGDNYPSKWK
KGNGIDSWNMYIRQCTSFAAFRLSSANGFQLPKGYGNACTWGHIAKNQGY
PVNKTPSIGAIAWFDKNAYQSNAAYGHVAWVADIRGDTVTIEEYNYNAGQ
GPERYHKRQIPKSQVSGYIHFKDLSSQTSHSYPRQLKHISQASFDPSGTY
HFTTRLPVKGQTSIDSPDLAYYEAGQSVYYDKVVTAGGYTWLSYLSFSGN
RRYIPIKEPAQSVVQNDNTKPSIKVGDTVTFPGVFRVDQLVNNLIVNKEL
AGGDPTPLNWIDPTPLDETDNQGKVLGDQILRVGEYFIVTGSYKVLKIDQ
PSNGIYVQIGSRGTWVNADKANKL
>M5005_Spy1790 acetyltransferase
MEIRRPTLKDKDAVLSMINEFLEQKSATDGLWHFNVNDFNYETWLEDSLR
QEMGLSSQGVPAIQYVAFDERSQAIGFLNLRLRLNERLLEKGGHIGYSVR
PSQRGKGYAKEMLKQAVSYAISKNITTILVTCDETNIASRAVIVANGGIL
EDSRGGTERYWIEEQRGDK
>M5005_Spy1129 CAAX amino terminal protease family
MKGFINYLKIAVLIILAMVFNVLPMILLQKQHDIPMVLNWGIGIFYLVIV
GSVLIVLWRLYQAKQDTSIKQQKMRLVDWGYLALFWLIIRVIAIVGTLVN
QLWSGQQVSANDAAIHTLARLIKGGFPLYTALFVLVIAFIAPIMEELVFR
GFPMIDLFKGKSLKVAGLVTSLVFALPHATNSVEFIMYSCMGIFLFVAYQ
RRGNLKDAILLHIFNNLIEVILLMSIGLGVI
>M5005_Spy1342 hydrolase, HAD superfamily
MVNIILLIVSALIGLILGYALISIRLKSAKEAAELTLLNAEQEAVDIRGK
AEVDAEHIKKTAKRESKANRKELLLEAKEEARKYREEIEQEFKSERQELK
QLETRLAERSLTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQLQVEK
LEEEKKAELEKVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDR
TVKTAKDLLAQAMQRLAGEYVTEQTITSVHLPDDNMKGRIIGREGRNIRT
LESLTGIDVIIDDTPEVVILSGFDPIRREIARMTLESLIADGRIHPARIE
ELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPDLIKIMGRLQFRTSFGQN
VLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDREVEGSHVEI
GMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGARN
ESMENYIKRLRDLEEIATSFDGVQNSFALQAGREIRIMVQPEKISDDQVV
ILSHKVREKIENNLDYPGNIKVTVIREMRAVDYAK
>M5005_Spy0930 ATPase associated with chromosome architecture/replication
MPSSFDLLGEMIGLLQTEQLTSSWACPLPNALTKRQDLWRALINQRPALP
LSKDYLNLEDAYLDDWRASFVPVSVKDCQKTNYTSLFLYHGDIRYLAVDA
IVNAANSELLGCFSPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIG
QAKLTSAYHLPASYIIHTVGPRITKGHHVSPIRADLLARCYRSSLDLAVK
AGLTSLAFCSISTGEFGFPKKEAAQIAIKTVLKWQAEHPESKTLTTIFNT
FTSEDKALYDTYLQKENNCE
>M5005_Spy1861 ABC transporter ATP-binding protein
MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFLKILAGD
IEPSTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYNIMKEKD
AIYMKADFSEEDGVRAAELEGIFAELGGWEAESEASQLLQNLNIPEDLHY
QNMSELANGDKVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLID
FENTVIVVSHDRHFLNKVCTHMADLDFGKIKLFVGNYDFWKQSSELAARL
QADRNAKAEEKIKELQEFVARFSANASKSKQATSRKKMLDKIELEEIVPS
SRKYPFINFKAEREMGNDFLTVENLSVTIDGEKIIDNISFILRPGDKAAI
IGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSKDFATEESI
LEWLRQFASKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
KLMLLKSNVLILDDPTNHLDLESISSLNDGIKDFKESVIFASHDHEFIQT
IANHIVVISKNGVIDRIDETYDEFLDNPEVQARVAELWK
>M5005_Spy0260 putative lipase
MLFQKKYDKIESTNYFGDDMSIDDYRPTYMVEAIYDLRANDLLRHGITAV
LVDLDNTLIAWNNPDGTPEVRAWLDEMTIADISVVVVSNNKHSRVERAVS
RFGVDFISRALKPFAYGIEKAIARYGFDRNEVIMVGDQLMTDIRASHRAG
IKSVLVKPLVASDAWNTKINRWRERRVMAKLEEKYGKLSYQKGI
>M5005_Spy1791 virulence factor
MLNIGIVGLGAISQKAYLPYMRQLSDITWHLSTRNAAVRQQVGQLFGHAI
LYSDVKELSKTNLDGVFIHAATSAHAELASLFLNQGIPVFMDKPIADNYL
MTKNLYDLAKENQTFLMAGFNRRFTPRVKKLSSLSTKRKVAVEKNDLNRP
GDMTFKLFDFFIHPLDTALFLTEGTLLKGHFQYHLEAGLLSQVMVTLMTE
SMTTTASMNLQSGSRREVMEVQRAEETYHLENLDELSIYKGTEKRVLGFA
SWDTTLHKRGFETMIDAFLEAISTGVNPVSPESSLLSHWICQQIADSQLS
YGELTVELPKD
>M5005_Spy1839 phosphohydrolase
MIVRNGKNFLTRDADDQYYTIGGTSLVGEKTHETVLRETLEEVGIRAKVN
QLAFMVENHFDIDDVFWHNIEFHYLVSPLEDPKLEMIENASDRFVNGFQS
INWIK
>M5005_Spy0355 hypothetical protein
MKKTLLLSTAVLTLAGTVALLTHSVDASTYSYYSTSHFLRQDGRETLREA
KYAAELQIRNLLSQYHINGKEYNNYFRYYYRQAMQARNIDEVNKIIEDLE
KNLQAQ
>M5005_Spy0750 ABC transporter ATP-binding protein
MIILQGNKLERSFSGDVLFQNISLQVDERDRIALVGPNGAGKSTLLKLLV
GEETPTSGEVNTKKDLTLSYLAQNSRFESDQTIYEEMLKVFEALRQDEKR
LRQMEMDMATVSGQVLTRLMTDYDLLTEHFRQQGGFTYESDIKAILNGFK
FDESMWQMTIAELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAW
LENYLANYQGALIIVSHDRYFLDKVATVTLDLTPNGLDRYSGNYSRFMAL
KAEKLVAEEKQFDKQQKEIAKLEDFVQKNIVRASTTKRAQARRKQLEKIE
RLDKPTGGRKSAHMTFHAEKPSGNVVLRVEEAAIGYGDQVLSEPINVDIN
KLDAIAVVGPNGIGKSTLIKSIIGQLPLLKGQLKYGANVETGYYDQTQSH
LTSSNTVLEELWQDFSTTPEVDIRNRLGAFLFSGDDVKKSVAMLSGGEKA
RLLLAKLSMENNNFLVLDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDR
YFINRLATKVLEITENGSTLYLGDYDYYLEKKAELEELARLAAGETVEET
KEASATDYQLQKANQKERRRLTRRYEEIEARLETIEERIGAIQEDMHASN
DTAQLIAWQKEWDQLDQEQEALMEEWETIAEQIES
>M5005_Spy0478 hypothetical membrane spanning protein
MSLFSNLPPSVLQWFAIFMSIIIEALPFVLLGTILSGCIEVFVTPELVQK
YLPKQKCLRILFGTFVGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLAT
APIINPIVLFATYSAFGNSLRFLILRLVGAALVAITLGVMLAFIVDDNIL
KDNAQPVHFHDYSHESLPKRIYLALVHAIDEFFDTGRYLVFGTLIASAMQ
IYVPTRVLTTIGHNPLTAILIMMLMAFILSLCSEADAFIGASLLSTFGVA
PVLAFLLIGPMVDIKNLMMMVKAFKGRFIVQFIGVSVLMIAVYCLLVGVL
>M5005_Spy0649 RNA binding protein
MDTIENLIIAIVKPLISQPDNLTIKIEDTPDFLEYHLDLDAQDIGRVIGK
KGRTITAIRSIVYSVPTLGKKVRLVIDEK
>M5005_Spy0306 CBS domain containing protein
MIAKEFETFLMSHLDNYLIPEQDLAIFIDTHNADHVMLLLVSNGFSRVPV
ITREKKYVGTISISDIMMYQSKRQLTDWEMSQTDIGEMVNTKIETISITS
SLTEIMHKLIDFPFLPVVDRANRFVGIITRKSILKAVNSLLHDFTDDYTI
IKK
>M5005_Spy1562 colicin V production protein
MLSLLIVLILTWNFYIGYSRGIILQSFYVLGALLSLLVANRFYIGLAHKL
TLWIPYSNPVEGTSVFFFKSVDIFVLDKVYYAGLAFFIIFLLGYALSRFL
GIFVHFLLLNYFDNQWTKCLSGGLAFLVSLLFLNMLLSIFATVPMPFLQH
YLHSSFLTRLVIEHLPPLTIIIQKLWIQAII
>M5005_Spy0305 putative phosphoesterase
MASKTIIVMSDSHGDRDIVQAIKDKYLGQVDAIFHNGDSELNSSDPIWAG
IYVVGGNCDYDTGYPDRLVTQLGTVTIAQTHGHLYHINFTWDKLDYFAQE
VVADICLYGHLHRPAAWQVGQTLFMNPGSVTQPRGEINEKLYARVELTDT
QIKVDYFTRDHKLYPSLSKEFKR
>M5005_Spy1137 putative competence protein/transcription factor
MTKILTALDDKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTIRRPHFA
HVQLAHCQFQAENESEEHLTLKAKLYTSLVRTEAVCIEKYLPELQQIADL
WVNDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTA
LQKQFLYFSSSLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLD
HNIMEMFRLPYQQEILYSYQKKMTVNLSKRIQRALLARHPKWLRRQEKAY
LSGYNLLMLTTDAFYPQWRPVQSSSGFCQIKGNLRPYYESFKVYYKKEKD
KKVQTLFSPKYYVKMDSNRK
>M5005_Spy1302 SAM-dependent methyltransferase
MVTKEVGHDFLARLGKKRLRPGGVEATNWLIEQGQFSQDCHVLEVACNRC
TTAIELAKTFGCQIDAVDLNPKVVKEAQERVAVEGLTRHITVSQASALSL
PFPDNHFDIVINEAMLTMLNAQAKEKALNEYWRVLKPGGRLLTHDVAYED
PKTRQVLDELRQTIHVNVAPLSLTGWQALYQEHGFSQVTYHHGKMSLMTP
RGMIKDEGLMNTLNIMRRGLKKENRQQFLKMRRFFTRTGKNLCYIAVKSV
K
>M5005_Spy0178 metal-dependent hydrolase
MKLTTLGSWGAYPYQDAGTTSYLVTGHDGFQLLMDAGSRALNELEKEISP
LDLDAVIISHYHPDHVADLGVLRHYFQLYPKHLWQPKVLPIYGHDEDRNE
FAKLSIPDVSEGRAYDVTGVEQIGSFDITFLKTVHPVVCYAFRIVERATG
QVLVFTGDSGYFEGLADFAKEADLFLADVYLYEGNENHMAHLTSKEAGLM
ASQAGVKKLVLTHMPPVPPDGINSKNHLEVLRQETQAYAGNIPVDLALPH
KSWNLGSLS
>M5005_Spy1023 terminase large subunit
MVVDLADIIPIGFKPVVQATWNPQILNIACKGGRGSGKSSNIAFIISRLI
IQYPVNAVCIRKTDNTLEQSVYEQIKWAISEQGLERYFKFNKSPLRITYI
PRGNYIVFRGAQNPERIKSLKDSRFPFAIGWIEELAEFKTEDEVKTITNS
LLRGELGDGLFYKFFYTYNPPKRKQSWVNKKYESQFQPSNTFVHASTYKD
NPFIAKEFIAEAEATRERSERRYRWEYLGEAIGSGVVPFDNLRFERITDE
QVADFDNIRNGIDYGYATDPLAFVRWHYDKKKNGIYAIDEYYGQKISNRQ
LAKWLTTKGYQSDEMFAESAEPKSNAELKNEFGIKRIKGVKKGPDSVEFG
ERWLDDLDFICIDPKRTPNIAREFENIDYQVDRDGNPKPRLEDKDNHAID
ATRYAMSDDMRATKTIVKTFKGGI
>M5005_Spy0501 integral membrane protein
MSAKLMSRIAIMSALCVVLRMVFSSLPNVQPVTAFLLSYLLYFGLAEAVL
VMMLCLFLSAFLLGFGPWVFWQVTCFVLVLLLWRFVLYPLSQQFPKYQLG
CQAFLVALCGLLYGVLIDTCFAYLYSMPWWSYVLAGMPFNIAHALSTLVF
FPVVMMLFRRLIGEQKI
>M5005_Spy0717 rhodanese-related sulfurtransferases
MSEKIRVLLYYKYVSIENAQEYAAKHLEFCKSIGLKGRILIADEGINGTV
SGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLG
LEDNNFDSDINPLETTGEYLNPKQFKEALLDEDTVVLDTRNDYEYDLGHF
RGAIRPDIRNFRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWMVRE
GFKDVGQLHGGIATYGKDPEVQGELWDGAMYVFDDRISVPINHVNPTVIS
KDYFDGTPCERYVNCANPFCNKQIFASEENETKYVRGCSPECRAHERNRY
VQENGLSRQEWAERLEAIGESLPEFVGA
>M5005_Spy0410 ATPase
MTTMTIAKGNQPIALQLGMLNRHGLIAGATGTGKTVTLKVLAEQLSLAGV
PVFLADIKGDLSNLTKAGEVTDKLAARLATIGVSDYQPQAFPVRMWDVFG
QNGQPLRTTISELGPMMLSRLLNLNDTQTGVLNIVFKIADEKGWLLIDLK
DLQAILKEVGDHASDYSSHYGNIAKQSIGAIQRSLLTLEQEGAHQFFGEP
ALDVADLMQLDVASGYGAINILSATKLFQSPTLYTTFLLWLLSELYKLLP
EVGDLDKPKMVFFFDEAHLLFKDAPKVFLEKVEQIVRLIRSKGVGIFFVT
QNPLDLPETVLAQLGNRIQHAFRAYTPKEQKAVRVAADTFRQNPDLDVAR
VITELEVGEALISVLNDKGQPSIVERAYIMPPKSSFAVLSEIESQQLVQS
SPFASKYSQSIDRESAYEKLAAKVLEDNRLAQEAIATAQREKEAKEAIKA
QAATKKANRRSVGRSHKTVVEKATDAFISTTVRTIGRELVRGLLGSLRKR
>M5005_Spy0391 phosphohydrolase
MRKNTNIVKRDHMPQDYISYIRSKVGHDKIILNFAGGILTNDDGKVLMQL
RGDKKTWTIPGGTMELGESSLETCKREFLEETGIEVEAVRLLNVYTHFEE
VYPNGDAVQTIVFIYELTAVSDMAIDNFHNEETLKLQFFSHEEIAELESV
SAKHRLMLEEYFSDSFAMGH
>M5005_Spy0747 Zn-dependent hydrolase
MTDIKMIALGGVREYGKNFYLVEINDSMFILDAGLKYPENEQLGVDLVIP
NLDYVIENKGKVQGIFLSHGHADAIGALPYLLAEVSAPVFGSELTIELAK
LFVKSNNSTKKFNNFHVVDSDTEIEFKDGLVSFFRTTHSIPESMGIVIGT
DKGNIIYTGDFKFDQAAREGYQTDLLRLAEIGKEGVLALLSDSVNATSND
QIASESEVGEEMDSVISDADGRVIVAAVASNLVRIQQVFDSATAHGRRVV
LTGTDAENIVRTALRLEKLMITDERLLIKPKDMSKFEDHELIILEAGRMG
EPINSLQKMAAGRHRYVQIKEGDLVYIVTTPSTAKEAMVARVENLIYKAG
GSVKLITQNLRVSGHANGRDLQLLMNLLKPQYLFPVQGEYRDLAAHAKLA
EEVGIFPENIHILKRGDIMVLNDEGFLHEGGVPASDVMIDGNAIGDVGNI
VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSHDILRE
SAELVNTTVGNYLKKDTFDWGELKGNVRDDLSKFLFEQTKRRPAILPVVM
EVR
>M5005_Spy0470 hydrolase, HAD superfamily
MIKLIATDMDGTFLAEDGTYNQEQLAALLPKLAEKGILFAVSSGRSLLAI
DQLFEPFLDQIAVIAENGSVVQYRGEILFADMMTKEQYTEVAKKILANPH
YVETGMVFSGQKAAYILKGASEEYIQKTKHYYANVKVINGFEDMENDAIF
KVSTNFTGHTVLEGSDWLNQALPYATAVTTGFDSIDIILKEVNKGFGMEH
LCQALGIKKAETIAFGDNFNDYQMLEFAGRAIATENARPEIKVISDQVIG
HCNDGAVLTYLKGLV
>M5005_Spy0853 short chain dehydrogenase
MKAIYQGAHAIQPQNIASTVSWVIHQPPHVNVNRIELMPVSQSYGPQPVT
RD
>M5005_Spy0941 nucleoside transport ATP-binding protein
MKGNDPMTQHVIEMREITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
STLMNMLAGLLEPTSGEIVINDKPVQIDSPSKSAKLGIGMVHQHFMLVEA
FTVAENIILGNEVVKNGCLDLNQASKDIKVLSEKYGLAINPSAKVSDISV
GAQQRVEILKTLYRGADILIFDEPTAVLTPAEIKELMTIMKNLVKEGKSI
ILITHKLDEIRAVADRVTVIRRGKSIETVDVAGATSQDLAEMMVGRSVSF
TTSKKAAEPKDVVLSIKNLEVDENRGVPAVKGLSLDVRAGEIVGIAGIDG
NGQSELIQAITGLRKVKSGSIMIKNNEVTHLSSRKITELSVGHVPEDRHR
DGLILDLSLAENTALQTYYKQPLSQNGILNYTKINDYARQLMKEFDVRGA
NELVPARGFSGGNQQKAIIAREVDRDPDLLIVSQPTRGLDVGAIEYIHKR
LIKERDKGKAVLVVSFELDEILNLSDRIAVIHDGKIQGIVSPENTNKQEL
GILMAGGSIHKEEGHV
>M5005_Spy1608 alpha/beta hydrolase
MKTIRIAKYLGILFLLITLISVGASFYFFHVAQIREEKSFINNKKRSTNN
PLYPAEQSFDALPYEKRQLTNRGLKQVGWYLPAAQKTKKTAIVVHGFTND
KEDMKPYAMLFHDLGYNVLMPDNEAHGESEGNLIGYGWNDRLNVMAWTDQ
LIKENPESQITLFGLSMGAATVMMASGERLPAQVTSLIEDCGYASVWDEL
KFQAKAMYNLPAFPLLYEVSALSKIRAGFSYGEASSVKQLAKNKRPTLFI
HGDKDDFVPTKMVYDNYKATKGPKEILIVKGAKHAKSFETNPEQYQKKIA
AFLKKVEK
>M5005_Spy0940 nucleoside transport system permease protein
MSKNAQKIAVPLISVLLGFLLGAIIMVIFGYDPIWGYEGLFQIAFGSVKN
IGEIFRSMGPLILIALGFTVASRAGFFNVGLSGQALAGWISAGWFALLNP
DMPRPLLILMTALIGMIAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILY
VGNAIVQRGYPESVKQSIDSTIQVSDNASYQTHWLSALTNNSRINIGIFF
AIIAIALIWFLLNKTTLGFEIRSVGLNPHASEYAGMSSKRTIILSMIISG
ALAGLGGVVEGLGTFENVFVQGSSLAVGFDGMAVSLLAANSPLGIFFSSF
LFGVLNIGAPGMNIAGIPPELVKVVTASIIFFVGSHYLIERYIIRPKKLV
KGGK
>M5005_Spy1670 oxidoreductase
MKHILFIVGSLREGSFNHQLAAQAQKALEHQAVVSYLNWKDVPVLNQDIE
ANAPLPVVDARQAVQSADAIWIFTPVYNFSIPGSVKNLLDWLSRALDLSD
PTGPSAIGGKVVTVSSVANGGHDQVFDQFKALLPFIRTSVAGEFTKATVN
PDAWGTGRLEISKETKANLLSQAEALLAAI
>M5005_Spy0316 SAM-dependent methyltransferase
MLKRPIHLSHDFLAEVVDKSSVVVDATMGNGNDTAFLAQLAKKVYAFDVQ
EQAIRKTSERLAQLGLSNAELILAGHEAVDQYVTEPVRAAIFNLGYLPSA
DKSIITLPNTTLQALSKLLTLLMVGGRIAIMVYYGHDGGSLEKDALLDFV
KQLDQRKVSAMLYQPLNQVNTPPFLIMLEKLADF
>M5005_Spy1700 acetyltransferase
MKIIEYKGNYRDDLIFMVLEAKNALRRIPSINPDLLTIETSYLEKEDCFW
LAVNEESRVIGSIAYSSIPKTNEVFLHRLFIKPSLKHQGIGSQLLAFAED
YLRKIGKSHVRIHLGQPKEQWFESYRFYPKHGYQFYDDTHLIKKLI
>M5005_Spy1135 oxalate/formate antiporter
MEKTKRYIIATAGILLHLMLGSTYAWSVYRNPILQETGWDQAPVAFAFSL
AIFCLGLSAAFMGNLVEQYGPRLTGTVSAILYASGNMLTGLAIDRKEIWL
LYIGYGVIGGLGLGAGYITPISTIIKWFPDKRGMATGFAIMGFGFASLLT
SPIAQWLIETEGLVATFYLLGLIYLIVMLFASQLIIKPTAAEIAILDKKR
LQNNSYLIEGMTAKEALKTKSFYCLWVILFINITCGLGLISVVAPMAQDL
TGMSPEMSAIVVGAMGIFNGFGRLVWASLSDYIGRRVTVILLFLVSIIMT
ISLIFAHSSLIFMISIATLMTCYGAGFSLIPPYLSDLFGAKELATLHGYI
LTAWAIAALTGPMLLSITVEWTHNYLLTLCVFIVLYILGLMVALRLKK
>M5005_Spy0388 hypothetical metal-binding protein
MPNIPNEVGSPSLTINLMYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGK
EEKEMSVTFVTNERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDLA
ADPSLAEMMAEFDAYIGELFISIDKAREQSQEYGHSFEREMGFLAVHGFL
HINGYDHYTLEEEKEMFTLQEEILTAYGLTRQ
>M5005_Spy0879 hypothetical protein
MKTVRIFYNPNSGKKESQLARQVKDYFCQHGFSEDSVKVITPKDADQAFQ
LAKQAAKDKIDLVIPLGGDGTLNKIIGGIYEGGAHCLIGLVPSGTVNNFA
KAMHIPLQITEALDTILTGQIKQVDICKANQQYMISSLTLGLLADIAADV
TAEEKRRFGPLAFLKDSIRILKRNRSYAISLISHNHRIHLKTKFLLITMT
NTIAGFPSFSPGAQADDGYFQVYTMKKVSFFKFLWHINDFKQGDFSKAEE
ISHFQANTLSLLPQAKKQAILPRTRIDGDKSDYLPIQLDIIPKAVSIIVP
TED
>M5005_Spy1468 tRNA (m(7)G46) methyltransferase
MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIEVGSGKG
GFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSL
TNYFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIH
FKTDNRGLFEYSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNK
GQVIYRVEANF
>M5005_Spy0363 phosphohydrolase
MKFEEKTLKRQTVFDGHIFKVVVDDVELPNNLGQSKRELIFHRGAVAVLA
ITPERKIVLVKQYRKAIERVSYEIPAGKLEIGEEGSKLKAAARELEEETA
YTGTLTFLYEFYTAIGFCNEKITLFLATDLIQVANPKPQDDDEVIEVLEL
TYQECMDLVAQGKLADAKTLIALQYYALHFGGEQ
>M5005_Spy0746 ABC transporter ATP-binding protein
MTKIIELINATVDVDNGFEDAKTILDNVTLTIYEHDFLTILGGNGAGKST
LFNVIAGTLSLTRGQIRILGQDVTHWPAEKRALYLSRVFQDSKMGTAPRM
TVAENLLIARQRGEKRSLASRKITEHLASFEDLVKRTGNGLEKHLETPAG
LLSGGQRQALSLLMATLKKPALLLLDEHTAALDPKTSQSLMQLTDEFVTK
DGLTALMITHHMEDALTYGNRLIVMKDGNIIKDLNQMEKEQLTITDYYQL
FD
>M5005_Spy0534 (R,R)-butanediol dehydrogenase/acetoin dehydrogenase
MSKVAIVTGAGQGIGFAIAKRLHADGFKIGILDYNEETAQAAVDKLSPED
AVAVVADVSKRDQVFDAFQKVVDTFGDLNVVVNNAGVAPTTPLDTITEEQ
FEKAFAINVGGTIWGSQAAQKHFRELGHGGKIINATSQAGCEGNPNLTVY
GGTKFAVRGITQTLAKDLASEGITVNAYAPGIVKTPMMFAIAHEVGKNAG
KDDE
>M5005_Spy0496 hydrolase, HAD superfamily
MITAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSVMNQAYIRFRHYSDVG
FPRVMAGEWTTEYFRFWRCKETLLEFGYREIDEAAGVHFQEVYEHELENI
TMLDEMRMTLDFLKSKNVPMGIITNGPTEHQLKKVRKLGLYDYIDPKRVI
VSQATGFQKPEKEIFNLAAEQFDMNPQTTLYVGDSYDNDIMGAFNGGWHS
MWFNHRGRQLKPGTKPVYDVAIDNFEQLFGAVKVLFDLPDNKFIFDVNDK
KNPILQMGINNGLMMAAERLLESNMSIDKVVILLRLTKQQEKVLRLKYAR
>M5005_Spy1449 DNA primase
MKQEKLIVKSSPLQELHIATGSSRTAKTWKNITLTWQELVERLEKPTVTQ
ETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADS
PSKDFLDRLDLLADYAFVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPV
ARYLANQLGMSNFDDTTYQSVRLMFWPSHSRDADFTFKYNDEAFLSVDEV
LDTYPDWHDSSFWPESPTHAVKRQREAKKQGDPLSKKGLIGAFCRNYDIR
QAIATFLSEVYEEGTTPDRYTYTDGSTANGLVIYDDVFAYSHHGTDPVGD
TLVNAYDLVRIHKFGEQDSEAKDNTPTNKLPSSKAMNAFVSDLPEIKDHL
MAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIKEVPIYWDG
LEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETVVAIKAQA
FSSEVFTESDLNKIVLANGVYDLRDNNFKTKFDPELHARSSHPVVYDPEA
TCETFEGFLRETVGAENIDFIFEWFGYNFYREYTIQKMLFIYGSGGTGKS
TLINILREMIGADNYSAVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLA
DGAALKMLTGEDTIHADRKNKEPINFYNYAKLSFAMNELPPMRDFSGGLK
RRMMILEMDKVLTQEVKAKYPLDKIMSEVPGIFNRAMEGLRKALSKRDFS
ISASMRSSVEKWEKGNDVVAMFLEDECELGEDFKVPVRDVYPAYKFYCQD
SGYKPLAKNAFNHRLRELNYENKNVKSDGKQAKNWVGFRLKSEF
>M5005_Spy0574 diacylglycerol kinase family
MKKQLRARLIYNPTSGQELMRKSVPEVLDILEGFGYETSAFQTTAQKNSA
LNEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLKKRPKMAIIPTGTTND
FARALKVPRGNPSQAAKLIGKNQTIQMDIGRAKKDTYFINIAAAGSLTEL
TYSVPSQLKTMFGYLAYLAKGVELLPRVSNVPVKITHDKGVFEGQVSMIF
AAITNSVGGFEMIAPDAKLDDGMFTLILIKTANLFEIVHLLRLILDGGKH
ITDRRVEYIKTSKIVIEPQCGKRMMINLDGEYGGDAPITLENLKNHITFF
ADTDLISDDALVLDQDELEIEEIVKKFAHEVEDLGQELEE
>M5005_Spy0852 short chain dehydrogenase
MGNIALVTGASAGFGRAIVEHLIADGIKVIGASRRLEKLKALETSFGSDN
FYPLQMDVTDTKAIDDALTSLPNQWQDITILVNNAGLALGLDKAYEADFE
NWMTMINTNIVGLIYLTRQLLPHMVSKDDGIIINLGSTAGTIPYPGANIY
GASKAFVKQFSLNLRADLAGSHIRVTNIEPGLCEGTEFSKGQNFQRSALM
VMRNG
>M5005_Spy0726 short chain dehydrogenase
MAQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQHIDNKE
CLELDITNPVAIEKMVAQIYQRYGRIDVLINNAGYGAFKGFEEFSAQEIA
DMFQVNTLASIHFACLIGQKMAEQGQGHLINIVSMAGLIASAKSSIYSAT
KFALIGFSNALRLELADKGVYVTTVNPGPIATKFFDQADPSGHYLESVGK
FTLQPNQVAKRLVSIIGKNKRELNLPFSLAVTHQFYTLFPKLSDYLARKV
FNYK
>M5005_Spy0488 hypothetical protein
MPAPLKKHNSVEQDDSYQESQSKFRDFQEFNGQSAKLKELVFFARIASFS
LITVLFAFVLLVMNLAPMFAFLFASIISLGITSLFAKVIKSLLM
>M5005_Spy1347 D-beta-hydroxybutyrate dehydrogenase
MTHTKEVAFITGAASGIGKQIGETLLKEGKTVVFSDINQEKLDQVVADYT
KEGYDAFSVVCDVTKEEAINAAIDTVVEKYGRIDILVNNAGLQHVAMIED
FPTEKFEFMIKIMLTAPFIAIKRAFPTMKAQKHGRIINMASINGVIGFAG
KSAYNSAKHGLIGLTKVTALEAADSGITVNAICPGYVDTPLVRGQFEDLS
KTRGIPLENVLEEVLYPLVPQKRLIDVQEIADYVSFLASDKAKGVTGQAC
ILDGGYTAQ
>M5005_Spy0292 aminodeoxychorismate lyase family
MTDFKDKDQQDQQRSFKEQILAELEKANQIRKEKEEELFQKELEAKEAAR
RTAQLYAEYKRQDAFQKESIAHNNKTAKHFQAIKGAVMTSEALKPTLLSE
KENSSLKTTNKRVVQANELQETASKESQVPLTIEKGHSVRRKLSKRQQTE
RAAKKISTVLISSIIITLLAVTLAGAGYVYSALNPVDKNSDAFVQVEIPS
GSGNKLIGQILQKKGLIKNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEE
IASALQEGGTAEPTKPSLGKILIPEGYTIKQIAKAVEHNSKGKTKKAKTP
FNEKDFLDLVTDEAFIQDMVKRYPKLLATIPTKEKAIYRLEGYLFPATYN
YYKETTMRELVEDMLAAMDATLVPYYDKIAASGKTVNEVLTLASLVEKEG
STDDDRRQIASVFYNRLNSGMALQSNIAILYAMGKLGEKTTLAEDATIDT
TINSPYNIYTNTGLMPGPVASSGVSAIEATLNPASTDYLYFVANVHTGEV
YYAKTFEEHSANVEKYVNSQIQ
>M5005_Spy0326 export protein for polysaccharides and teichoic acids
MSTEKKQLTQEELMVQGAAWSTAGNFISRLLGVLYIIPWYIWMGQYAIQA
NALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQTEHSYQLIRSTL
KLMLGLGLIFSAIMYLGSPLFASLSGGDDTLVPIMHSLSLAVFIFPVMSV
IRGIFQGHNNIKPYAVSQIAEQLIRVIWMLLTTFFIMKLGSGDYASAVTQ
STFAAFIGMVASMGVLGYYLWKQGLLAAIFSKPDHTVSIDIKGLLLETLK
ESIPFIVTGSAIQAFQLIDQWTFVNTMTLFTDYSRSQLLVLFGYFNANPA
KITMVLIAVAASIGGVGIALLTENYVKKDMKAAARLIINNIEMLVMFLLP
ALTGAIILARPLYSVFYGASEERAIHLFVAVLFQTLLLALYTLFSPMLQA
LFENRKAIYYFAYGILIKLVLQIPLIYLLHAYGPLLATTIALVVPIYLMY
RRLYQVTHFNRKLLQKRLLLTLIETLLMGLVVFVANWLLGYAFKPTGRLT
SLLYLLIIGGLGMTVYTALTLLTHQLDKLIGSKASRLRQKLGWH
>M5005_Spy1331 peptidyl-prolyl cis-trans isomerase
MDAKLKYKAKKIKMVFFDIDDTLRVKDTGYMPESIQRVFKALKAKGILVG
IASGRARYGVPQEVQDLHADYCVKLNGAYVKDDAKTIIFQAPIPADVVVA
YKKWADDMGIFYGMAGRHEAVLSARNDMISNAIDNVYAQLEVCPDYNEYH
DVYQMWTFEDKGDGLQLPAELAEHLRLVRWHDNSSDVVLKGTSKALGVSK
VVDHLGLKPENILVFGDELNDLELFDYAGISIAMGVSHPLLQEKADFITK
KVEEDGILYALEELGLIDKELQFPQLDLPNHKGPKATIKTNHGDMTLVLF
PDHAPKTVANFLGLAKEGYYDGIIFHRIIPEFMIQGGDPTGTGMCGQSIY
GESFEDEFSDELYNLRGALSMANAGPNTNGSQFFIVQNSKIPYAKKELER
GGWPAPIAASYAANGGTPHLDRRHTVFGQLVDETSFQVLDLIAGVETGAQ
DKPKEDVIIETIEVFD
>M5005_Spy0921 ABC transporter ATP-binding protein
MSILEVKQLSHGFGDRAIFENVSFRLLKGEHIGLVGANGEGKSTFMSIVT
GHLQPDEGKVEWSKYVTAGYLDQHTVLESGQTVRDVLRTAFDELFKTENR
INEIYASMADDKADIAVLMEEVGELQDRLESRDFYTLDAKIDEVARALGV
MDFGMESDVTSLSGGQRTKVLLAKLLLEKPDILLLDEPTNHLDAEHIEWL
KRYLQHYENAFVLISHDISFLNDVINIVYHVENQSLVRYTGDYYQFQAVY
EMKQSQLEAAYERQQKEIANLQDFVNRNKARVATRNMAMSRQKKLDKMDI
IELQAEKPKPNFEFKQARTPSRFIFQTKNLVIGYDYPLTKEPLNITFERN
QKIAIVGANGIGKSTLLKSLLGVIEPLEGHIVTGDFLEVGYFEQEVTGVN
RQTPLEVVWDAFPALNQAEVRAALARCGLTSKHIESQIQVLSGGEQAKVR
FCLLMNRENNVLILDEPTNHLDIDAKNELKRALKAYKGSILMVCHEPDFY
NGWVTDTWDFSKLT
>M5005_Spy0674 ABC transporter ATP-binding protein uup
MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTTLLDVLS
GRLGFDGDHSPFSKANDYKIAYLTQDPEFNDAASVLDTVLSADVKAIQLI
RQYELLMANYTEDKQESLESLMSEMDRLDAWSIESDVKTVLSKLGITDLE
QKVGDLSGGMRRRVQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKT
AKKTVLFITHDRYFLDHVATRIFELDKAGLTEYQGNYQDYVRLKAEQDER
DAANLHKKKQLYKQELAWMRTQPQARATKQQARINRFSDLKKEVHQDSSA
DKLEMTFETSRIGKKVIHFEDLSFAYGDRQLIKDFNLIIQNKDRIGIVGD
NGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMDETKRVINY
LQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLK
LLIEKPNVLLLDEPTNDLDIATLKVLENFLANFAGPVITVSHDRYFLDKV
ATKILAFEEGDIRVFYGNYSDYLDEKVFEKETVEADLAKTTVTEEVPLPQ
KEERKRMSYLEKQEWAQIEDKIATIEANIEEIENQMLTVVSDYGQLAQLQ
KELDQRNNDLLLAYERFEYLSGLDI
>M5005_Spy1602 predicted kinase related to hydroxyacetone kinase
MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNMSMTMDN
GAKEVADKPASTVGEVGQMLSKGLLMGARGNSGVITSQLFRGFGQSIKGK
DELTGKDLAQAFQVGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTD
DAVEVMQAALDGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSA
LNGDYVTSADFKATPANMSEMINAEHHKSVVGHVATEDITYGYCTEIMVA
LKQGPTYVKEFNYDEFQGYLSGLGDSLLVVNDDEIVKVHVHTEDPGLVMQ
EGLKYGSLIKIKVDNMRNQHEAQVQKTDVEKNKAEVKDFGLIAVVAGEGL
SEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILPNNKNIFMA
AQSAAEVVDIPAAVVATRTVPQGFTSLLAFDPSKSLEDNVADMSTSLSDV
VSGSVTLAVRDTTIDGLEIHENDFLGMVDGKIIVSNPDMEATLKAAFEKM
IDEDSEIVTIFVGEEGDQDLAEELAGYLGETYEDVEVEIHQGDQPVYPYL
MSVE
>M5005_Spy0315 Fe-S oxidoreductase
MKKRYQTLNEHYRQLFGAKMFKVPIDAGFDCPNRDGTVAHGGCTFCTVSG
SGDAIVAPDAPIKEQFYKEIDFMHRKWPDVNRYLVYFQNFTNTHDTVDVI
RDRYEQAINEPGVVGINIGTRPDCLPDDTIAYLAELSERMHVTVELGLQT
TYEETSRLINRAHSYDLYKETVRRLRHYPNINIVSHLINGLPKETHDMML
ENVRRCVTDNDIQGIKLHLLHLMTNTRMQRDYHEGRLKLLSQKDYVSIIC
DQLEIIPKHIVIHRITGDAPRDMLIGPMWSLNKWEVLNAIDKEMERRGSF
QGCKVD
>M5005_Spy0300 hydrolase, HAD superfamily
MHYTEDKEYMEHVGHLIAHPRFQKLSHIVQHQHSTRLEHSINVSYSSYKL
AKRFGWDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLT
ELNKKEEDIILKHMWGATIAFPRYKESYIVTMVDKYWAVKEAVTPLRQKW
SNRRFLRRKTLQSHNR
>M5005_Spy0835 class B acid phosphatase
MKKEFTSILFTVSFCGIIALPVEASGPKVPYTQEGITAISNQATVKLISI
ADIASSLEGQKPITVSFDIDDTLLFTSQYFQYGKEYITPGSFDFLHKQNF
GTWSLNGEIRILFQKSMQSN
>M5005_Spy0836 class B acid phosphatase
MVAKRGDQDSIPKEYAKQLIAMHQKRGDKIVFITGRTRGSMYKKGEIDKT
AKSLAKDFKLDKPIAINYTGDKAVKPYQYDKTYYIKKNGSQIHYGDSDED
INAAKEAGARPIRILRAPNSTNLPLPKAGGYGEEVLENSAY
>M5005_Spy0137 nucleoside-binding protein
MNKKVMSLGLVSTALFTLGGCTNNSSKQTTDNSLKIAMITNQTGIDDKSF
NQSAWEGLQAWGKENKLEKGKGYDYFQSANESEFTTNLESAVTNGYNLVF
GIGFPLHDAVEKVAANNPDNHFAIVDDVIKGQKNVASITFSDHEAAYLAG
VAAAKTTKTKQVGFVGGMEGDVVKRFEKGFEAGVKSVDDTIKVRVAYAGS
FADAAKGKTIAAAQYAEGADVIYHAAGGTGAGVFSEAKSINEKRKEEDKV
WVIGVDRDQSEDGKYTTKDGKSANFVLTSSIKEVGKALVKVAVKTSEGQF
PGGQITTFGLKEGGVSLTTDALTQDTKKAIETAKKAIIEGTITVPEN
>M5005_Spy1134 O-methyltransferase
MVKSYSKTANHNMRRPVVKEELVHYMRTRQKQTTGFLAELEQFARQENIP
IIQPEVVAYFRFLLQSLQPKHILEIGTAIGFSALLMAENAPDATIVTIDR
NREMIDFAKANFAKYDSRQQIRLLEGDAADILSTLEGNFDFVFMDSAKSK
YIVFLPEILRLLKVGGVVILDDVFQGGDITKPIEDIRRGQRTIYRGLQSL
FDATLTHPNLTTSLVPLSDGLLMIRKNQADIVLPD
>M5005_Spy0223 GTPase
MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVDFSAEDN
SEGYILAIHPRKNSLVRPPIVNIDQAVVIMSAKEPEFNSNLLDRFLILLE
HKAIHPVVYISKMDLLDSPEEIKAIGRQYQAIGYDFVTSLEELLPLLADK
ITVFMGQTGVGKSTLLNRIAPELALEIGEISDSLGRGRHTTRAVSFYNTH
GGKIADTPGFSSLDYDIANAEDLNEAFPELRRLSHECKFRSCTHTHEPKC
AVKAALETGELWPVRYEHYLQFLSEIENRRETYKKVIKRK
>M5005_Spy0880 conserved membrane protein
MNQTFKQSLPLSFSEEVANSVTHAIGAFAMLILLPISASYAYQTYDLKAA
IGISIFVISLFLMFLSSTIYHSMAYGSVHKYILRIIDHSMIYIAIAGSYT
PVALSLVSGWLGYIIIVLQWGITLFGILYKIFAKRINEKFSLMLYIVMGW
LVVFILPVIIQKTSLAFGLLMLFGGLSYTIGAVFYAKKRPYFHMIWHLFI
LLASALQFIAITFFML
>M5005_Spy1490 3-oxoacyl-[acyl-carrier protein] reductase
MEIKGKNIFITGSTRGIGLAMAHQFASLGANIVLNGRSAISEELVASFTD
YGVTVVTISGDVSEASEAKRMVNEAIESLGSIDVLVNNAGITNDKLMLKM
TEEDFERVLKINLTGAFNMTQSVLKPMIKARQGAIINVSSVVGLTGNIGQ
ANYAASKAGMIGFTKSVAREVAARNICVNAIAPGFIESDMTGVLPEKMQE
QILSQIPMKRIGKAQEVAHLASFLVEQDYITGQVIAIDGGMTMQ
>M5005_Spy0724 cystathionine beta-lyase/cystathionine gamma-lyase
MNNYIDLAKTYGGFTSLDTNYLNHLLASLTDQQKLAFITPPPSVINAYFA
EIYQKQSPQAATDYYFNLSKALGLFTDQPSFEEEKPFVRLNLSGKAYGFA
YQNDQEVALVFSEKAEPKKPELFFELTQIFPQYMVYEDKGQLKMQAKQFE
QGECEDITPDDTLLSKIYRLANGITMLKGFNVEELWALSQTFSGQKYYDF
AQREFMIYITQ
>M5005_Spy1787 glyoxalase family protein
MIYPYNSTISLGTVSLNVTDLAKMTTFYTSIIGLQVLSQDTTSRQLTTDG
KTVILELRQTPLPGDKAYGLYHTAFLVPDRHSLGLVLNHFLTRSISLEGA
ADHGHSEAIYLSDPEGNGIEIYHDKAVEHWDIRDNGQIIGVTEPTDTKSI
LEQLTDIPKHFLLAQDTRIRHVHLSVKNALASSLLYQKVFDLGDKMTIPS
ASWIASGNYYHHLAFNHWSAPYLKKHQEGAPGLAFLTIHIETPLLFSATL
KKARLHGLAILQEDSSSFTTEDEEGIRVNVILGQD
>M5005_Spy0842 redox-sensitive transcriptional regulator Rex
MVIDKSIPKATAKRLSLYYRIFKRFHADQVEKASSKQIADAMGIDSATVR
RDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTNVILVGCGNIGRALL
HYRFHDRNKMQIAMGFDTDDNALVGTKTADNIPVHGISSVKERIANTDIE
TAILTVPSIHAQEVTDQLIEAGIKGILSFAPVHLQVPKGVIVQSVDLTSE
LQTLLYFMNQNHLD
>M5005_Spy0789 hydrolase, HAD superfamily
MHYNFLFFDLDHTLLDFDAAEEVALTKLLEEYQVIDIKAYKDYYKPMNQN
LWKQLEGGDISKADLVNSRFALLFAHFGVTVDGRQLAEGYQKHLKDQGQV
YAGAKELLADLTAQGYNLYAATNGIATIQQGRLQASGLAPYFKAIFISEQ
SGSQKPKKAFYDWMTQQVSNYQPDQALMIGDSLSADVQGGINAGMDTLWY
NPKHLLNNSPVHPTYEVSDYQALLNCIAE
>M5005_Spy1595 Zn-dependent hydrolase
MTNISLKPNEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFPEDDLL
GIDYVIPDYSYIVDNLDRVKALVITHGHEDHIGGIPFLLKQANIPIYAGP
LALALIRGKLEEHGLWREATVYEINHNTELTFKNMSVTFFKTTHSIPEPV
GIVIHTPQGKIICTGDFKFDFTPVGDPADLQRMAALGEEGVLCLLSDSTN
AEIPTFTNSEKVVGQSILKIIEGIHGRIIFASFASNIYRLQQAAEAAVKT
GRKIAVFGRSMEKAIVNGIELGYIKVPKGTFIEPSELKNLHASEVLIMCT
GSQGESMAALARIANGTHRQVTLQPGDTVIFSSSPIPGNTTSVNKLINTI
QEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVHGEYRMQKV
HAGLAMDIGIPKENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
DIGAAVLRDRRDLSEDGVVLAVATVDFNTQMILAGPDILSRGFIYMRESG
DLIRESQRVLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPII
IPMVLTPDKH
>M5005_Spy1291 ATP-dependent RNA helicase
MILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFLIGLYHDLG
KADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFN
EMVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKG
YALKLEKKLCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWDYYQSCM
VRLYLSLLKNADILDTVNAYGLKISPMDKTERSFLKHSYLAAIEQKYASF
GQPNNQLNTIRTEIAERVKERGKRDSKGIYRLDLPTGAGKTNLSMRYAFH
QLVHHDKSRFFYITPFLSVLEQNASEIRKVTGDLGVLEHHSNVVKQANED
DDDKDSLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANLRRFSSLINSV
VILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIVLCTATQPAYDSSEIDHR
ICYGGNLGELAEIVELTIEEKQIFSRTELRKFDDSDQKVHLTDVINLILG
EENSVLAIFNTKKTVHNCYTMLKDMTDRPVYQLSTNMCAQHRLDLIAKIK
TELQNNIPIICISTQLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNREGK
RDKGQVTLVNLTNEEENISRLTEIKTKKEATESILHKIGSPIDISTLNRD
FFEYYYANNQGLMDYPLEDNLSIYDYLSLNIYQTANKKFKGKLKQAFKTA
GAKMNLINNDMIGILVPYGEAEKKLAYLEELGVSHFLSAKDYQTIKSLLK
ELQPFTVNVRENDPLFETTKSYLNGQILVLTSEYYDTERGVKYDSASFYF
>M5005_Spy1478 hydrolase, HAD superfamily
MTKKLIAIDLDGTLLHHDNTISTYTQKTIKAVQDKGHHVIISTGRPYRMA
LGYYLQLNLKTPIITFNGALTHMPEQKWAYEHNVTLDKGYLLRLLKYQDD
FQMDFIASEYRKNVYITMTNPESIDPQLFGVDEITQDMALEITKITRNPN
ALLMQTHHEDKYALAKNMRACFKDEIEIDSWGGPLNILEISSKNVNKAYA
LNYLLGIYNMDKKDLIAFGDEHNDTEMLAFAGTGYAMKNASPVLLPYADQ
QLNFSNEEDGVAKKLEELFL
>M5005_Spy0335 corrin/porphyrin methyltransferase
MQVQKSFKDKKTSGTLYLVPTPIGNLQDMTFRAVATLKEVDFICAEDTRN
TGLLLKHFDIATKQISFHEHNAYEKIPDLIDLLISGRSLAQVSDAGMPSI
SDPGHDLVKAAIDSDIAVVALPGASAGITALIASGLAPQPHVFYGFLPRK
AGQQKAFFEDKHHYPETQMFYESPYRIKDTLTNMLACYGDRQVVLVRELT
KLFEEYQRGSISEILSYLEETPLKGECLLIVAGAQADSEVELTADVDLVS
LVQKEIQAGAKPNQAIKTIAKAYQVNRQELYQQFHDL
>M5005_Spy0652 hypothetical cytosolic protein
MITQEMKDLINNQLAMVATVDAKGQPNIGPKRSMRLWDDKTFIYNENTDG
QTRINIEDNGKIEIAFVDRERLLGYRFVGTAEIQTEGAYYEAAKKWAQGR
MGVPKAVGIIHVERIFNLQSGANAGKEINSESN
>M5005_Spy1849 zinc protease
MTKLVKINYPNIDEDLYYVKLENGLTVYFIKKIGFLEKTAMLTVGFGSLD
NKLTVDDESRDAPAGIAHFLEHKLFEDESGGDISLKFTQLGAETNAFTTF
NQTSFFFSTASKFQENLELLQYFVLSANITDESVSREKKIIGQEIDMYQD
DADYRAYSGILQNLFPKTSLANDIAGSKASIQKITKILLETHHTYFYQPT
NMSLFIVGDIDIDETFLAIQRFQTTLSYPDRKRVTVDPLHYYPVIKSSSV
DMDVTTAKLVVGFRGYLTLTQHSLLTYRIALKLFLSMLIGWTSKIYHTLY
EDGKIDDSFDVDVEIHHNFQFVLISLDTPEPIAMSNYIRQKLATIKISKE
FTNEHLNLLKKEMYGDFIQSLDSIEHLTHQFSLYLSDSDKETYFDIPKII
ERLTLKDVVTIGKAFFEKADASDFTVFPK
>M5005_Spy0177 bioY protein
MFTTKELVKVAMMTTLIIILGFIPAIPLGFIPVPIVLQNLGVMLAGLMLG
GKKGTLSVFLFLVIGLFLPVFSGSRTTIPVLMGPSAGYVIAYLLVPIVFS
LLYRNWFSKSTPLAFLALLISGVVLVDVLGAIWLSAYTGMSLVTSLLSNL
VFIPGDTIKAIIATIIAVKYKDSFLNTKQ
>M5005_Spy0429 daunorubicin resistance transmembrane protein
MWSFWKRYRPFLSAGIQELITYRVNFFLYRIGDVMGAFVAYYLWKAVFDS
SKQSLINGFTLSDMTFYIIMSFVTTLLTKSDSSFMIGEEVKDGSIIMRLL
RPVHFAASYLFMEIGFRWIVLMSVGFPFLMVLSGIKVMAGLSILQVLASS
CLYLVSLLLAFLINFYFNICFGSSAFVFKNLWGSNLLKNALVAFMSGSLI
PLAFFPKMVSIVLSFLPFSSLVYTPVMIVIGKYSLSQIMVALSLQIFWLL
VMVVLSQVIWKKVQYHLTIQGG
>M5005_Spy0191 integral membrane protein (rhomboid family)
MTQLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGAQAIYQVGGMFGLLV
KAMPDQLWRLVTPIFIHIGFGHFFVNGLTLYFVGQIVEDLWGSRRFLLLY
VLSGVMGNAFTFWLTPETVAAGASTSLFGLFAAIVVLSFLGKNQALKDLG
KSYQTLIVVNLLMNLFMPNVSMAGHIGGVVGGALLSIVFPTKMRVITVKK
TKRMLALVSYGIILVGVLVLGFL
>M5005_Spy0787 hypothetical protein
MPPKTIDIEKYHQLAWQRQAEHRKFLATLKKKPPKHLDKIVQDIHQEVFQ
EIDCTSCANCCKDLGPDLTETDIVKIAKLFRMKLATFEKTYLRVDEDDDK
VFRFMPCPFLGGDNL
>M5005_Spy1374 hypothetical protein
MEKKRQRLYDVIRQAYDYPENRENVALSQLLLAASNRLIKHSNPLLVAYQ
LNQDVDNYLLDNDILLPKSLCRFKQSLEKYILEEASLV
>M5005_Spy0759 hypothetical membrane associated protein
MTYTSLKSPENQDYIYDLTIAHLYGNLMNTYGDNGNILMLKYVAEKLGAR
VTVDIVSINDTFEQDDYDIVFFGGGQDYEQSIVAKDLPSKKAALADYIAN
NKVVLAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKI
HNDEFNETYYGFENHQGRTFLSGDEKPLGRVVYGNGNNKEDQTEGVHYKN
VYGSYFHGPILSRNVNLAYRLVTTALKKKYGSAISLPSYDDILKQEITEE
YADLKSKASFNKV
>M5005_Spy1584 NAD(FAD)-utilizing dehydrogenases
MTQYDTIIIGGGPAGMMAAISSSYYGYKTLLIEKNRRLGKKLAGTGGGRC
NVTNSGNLDVLMAGIPGNGRFLYSVFSQFDNHDIIAFFEENGVKLKEEDH
GRMFPTTDKSRTIIDALEKKIKALGGQVLTSTEVVSVKKQDDLFYLKSAD
QTFTCQKLIVTTGGKSYPSTGSTGFGHDIARHFKLTVTDLEAAESPLLTD
FPHKVLQGISLDDVTLSYDKHVITHDLLFTHFGLSGPAALRLSSFVKGGE
IAELDFLPHLSTDDLTAYLSDQRDKNIKNALKGLLPERVADFLSEDYPEK
VKQLSPKQEKELLDKLKHLQIPITGKMSLAKSFVTKGGVDLKEINPKTLE
SKKVPGLYFAGEVLDINAHTGGFNITSALCSGWIAGKSS
>M5005_Spy1207 phage protein
MTKQHRETLIWYRASHQERERLLDFGLVDKSQYMTLLRQLRKKYAI
>M5005_Spy1850 zinc protease
MKIVQGVQLHLIKTKQFKTNHITFRFSGDLNQKTVAKRVLVAQMLATANE
CYPTVRQFREKLARLYGASLSTNVLTKGLVHIVDIDITFIQDRYACNGEK
ILDEMIQFLKDILFSPLLSIAQYQPKVFETEKNNLINYIESDREDSFYYS
SLKVKELFYCNKNLQMSEYGSPELIAKETAYTSYQEFHKMLNEDQIDIFI
LGDFDDYRVVQLIHQFPLDNRNKNLNFFHLQNSVNIIKESIEKRAVHQSI
LQLAYHFPSVFGQRDYYALVLLNGLLGSFAHSRLFIKIREEEGLAYSIGC
RFDSYTGLFEIYTGIDSQHRTKTLQLIIQELNAIKMGRFSEQLIKKTRSM
LLNNALLSEDYNKNIIERIYRSSYIDSSYSIKNWIKGVNEVNKADIIKVA
NLLKLQTVYFLEGI
>M5005_Spy0444 hypothetical protein
MSRNQDCKNILIIGFGKIGKIKAYKWLSRGYEVYVKDLKFSSMKYLNTNS
DVLDDLSRQYFTIEICTPTNHHLTLLKTVITRYVYSYISIEKPLCNRLED
LEEMKSLVESHPHLAKKIFASEQYFFSKILEKLLQVDCFSLDKIKEITVD
FSKDRIEDNENGRFLDKEILGYGIEIPHIIAVISYLGISLEEFKKGIFVN
AIYIKDLEKHDYSIEILSCINQTVIKIISNLGSFAIREGKIEGGDAKTVR
RVTIDDKTILFDPHPKLERYKSELVTGTNTFQIHDDMMDTYISLLEGNAI
PEDCYINNAIEITKLLINLYSECEKIYL
>M5005_Spy1651 hypothetical cytosolic protein
MKKRILLVDGYNMIAFWQSTRQLFKTNQLDQARNTLLTKLNHYAHFENIN
IICVFDAQYVPGLRQRYDQYYISVVFTEEDETADSYIERMAAELNTAIHM
VEVATSDLNEQWTIFSQGALRVTARELEQRVHTVKADLDKMSRDIDLKTP
KLRPFDQGQLIQLKDFMSQLDR
>M5005_Spy0882 GTP-binding protein
MAMIQWFPGHMSKARRQVQENVKHVDFVTILVDARLPLSSQNPMLTKIVG
DKPKLMILNKADLADATRTKEWKAYYESQGIKTLAINSKEQSTVKKVTEA
AKELMADKIQRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIAVVG
NKPGVTKGQQWLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQL
LPMDEVTIFGLNYFREYYPNRLTKRFKNIPLEEEAPEIIMTLTRQLGFKD
DYDRFYTLFVKEVRDGKLGQYTLDQVGDMDAD
>M5005_Spy0834 Zn-dependent alcohol dehydrogenases and related dehydrogenases
MNWLITSQPYKKLNMKAATYLSTGNLQLIDKPKPVIIKPTDAIVQLVKTT
ICGTDLHILGGDVPACKEGTILGHEGIGIVKEVGDAVTNFKIGDKVIISC
VTSCHTCYYCKRGLSSHCQDGGWILGHLINGTQAEYVHIPHADGSLYHAP
DTIDDEALVMLSDILPTSYEIGVLPSHVKPGDNVCIVGAGPVGLAALLTV
QFFSPANIIMVDLSQNRLEAAKTFGATHTICSGSSEEVKAIIDDITNGRG
VDISMECVGYPATFDICQKIISVGGHIANVGVHGKPVDFNLDELWIKNIT
LNTGLVNANTTEMLLNVLKTGKIDATRLITHHFKLSEVEKAYETFKHAGA
NNALKVIIDNDIS
>M5005_Spy1393 hydrolase, HAD superfamily
MIQLIAIDLDGTLLNQDKQIPKENITAIQEAAQSGLKIVLCTGRPQSGTR
PYFDQLGLTQEEFLIINNGCSTYSSPDWQLRHSKMLKVSDIELLEELSQS
FPDIYLTLTEENDYLVLEEEVPDLVQEDGDLVFTIVKPVSLAELSDTPRL
IFQAMYLGEKAALDAFERAVRNQLSQSFHVVRSQDNILEILPQGVSKASA
LKELVEDLGLTADQVMAIGDAPNDIEMLTYAGLGVAMENASAAIKPLADK
VTLTNDMAGVAQAIRQFALVAQKD
>M5005_Spy0528 beta-phosphoglucomutase/glucose-1-phosphatephosp hodismutase
MIKGIIFDMDGVLFDTEPFYLRRREDFFKTKGIPIDHLNSKDFIGGNLQE
LWKELLGKNRDDAIVKAITTDYDAYKQAHKPPYQKLLITEVNSCLEQLEK
QGIKLAVASNSKRQDVLLALETTQIKDYFEIILAREDVSRGKPYPDIYNK
AVQKLGLQKKQLLVVEDSQKGIAAAKAANLTVFAITDYRYGIDQSQADHK
IDHLGQLCVKIGCFGS
>M5005_Spy0040 adhA, alcohol dehydrogenase
MYNLFVTDYKKVIIRWRTDMKAVVVNQASTGVEVVEHDLPNIGHGEALVK
VEYCGVCHTDLHVAHGDFGQVPGRILGHEGIGIVEEIGEGVTSLKVGDRV
SIAWFFEGCGHCEYCTTGRETLCRSVKNAGYSVDGGMSEYAVVTADYAVK
VPEGLDPAQASSITCAGVTTYKAIKEAGAAPGQWIVIFGAGGLGNLAVQY
AKKVFNAHVVAVDINNDKLELAKEVGADILVNGKEIEDVPGYIQEKTGGA
HGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVLDGIKV
VGSLVGTRKDLEEAFAFGAEGLVAPVVEKVPVDTAPEVFDEMERGLIQGR
KVLDFIS
>M5005_Spy0612 amrA, transcriptional activator
MINPSKQNQTIFLWNMLGSLSTAVISVILLMVVTRLLTSADSDIYAFAYS
FANMMVVVGLFQVRNYQATDINEKYSFSQYLVARLMTCLLMLAITVIYLT
LTKTDSYKSTIVFLVCFYRSTDAFSDLYQGMFQQHERLDIAGKSLAYRNT
LIFMVYTAIILYSKNLTLALVAVCIVSLVFIMYYDIGHSKKFQKLMFSEL
LSNISFQNSLKLLKESFPLFLNGFLIIYIYTQPKYAIELMTTLGEVALGS
QTIFNILFMPAFVMNLLILFFRPHITQMAIALIRGQIKEFNKIQVQLFAY
LGVFSLIALVGSGLFGIPFLSILYGTNLTDYWVDFMLIMLGGSIGSFATV
IDNILTAMRKQQLLLIPYTGGFLISLLITNLFVMKYHILGAALSFLITML
VWLGLSIMIYLFIMNRFKKGRVNATIYD
>M5005_Spy0227 cbf, CMP-binding factor
MKINQMKKDQLFEGFYLIKSAEVRKTRAGKDFISLTFQDDTGEISGNLWD
AQPYNVEEFTAGKVVFMKGRREVYNGTPQVNQITLRNVRPGEPNDPKDFK
EKAPVSVTEVRDYLEQMLFKIENATWQRIVRALYRKYDKEFYTYPAAKTN
HHAFESGLAYHTATMVRLADSIGDIYPDLNKSLLFAGIMLHDLAKVIELT
GPDNTEYTVRGNLIGHISLINEEITKVISELQIDDTKEEVIVLRHVILSH
HGQLEYGSPVRPRIMEAEIIHMIDNIDANMMMMTTALSRVSEGEMTNRIF
AMDNRSFYKPNY
>M5005_Spy1800 cinA, colligrin
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLL
SVITTASQRSNLVILCGGLGPTKDDLTKQTLAKYLRKDLVYDEQACQKLD
DFFAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVL
PGPPSELKPMVNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIE
NQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQLLSRKTLEGQ
PLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPG
ASQVFNGGFVTYSMEEKAKMLGLPLEELKSHGVVSAYTAEGMAEQARLLT
GADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRLDV
RYIATLHAFNMVRKTLLKLENLL
>M5005_Spy1147 comEC, COME operon protein 3
MTFSWTKLVPLSKIQFAFLILVFFYQIHSPSWLTFLLSLSLICLLVKRLS
KKEFLGVFAILSFCALFLLYQKQQLVQKLEIQPVQITSVALVPDSIRING
DQLAVLGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVMHAKVTLEKAEEV
RNFKGFNYQTFLTYQGIYRIGKVEQIEQLEVISPESICDYLSSLRRRAIV
HCQQHFPRPMSHYLTGLLFGYLDKSFGEMTDYYSQLGIIHLFALSGMQVG
FFLTCFRRVLLLLAVPLEWIKWIELPFACFYAALTGYSISVIRSLVQSQL
RHLGIKGLDNLACTFLLVFLWDAHFLMTVGGVLTFSYAFLLTVVTVEELS
GAKRQLVQVLTISLGILPFLLFYFSSFNPMSMVLTGLLSYLFDLFILPLL
CLVFCLSPLVTVSICNHLFILLEKVIQFLGNTFNSSLVFGSPTSWHLLIL
VISFAIFYDYRQVRQRVITCGLVIALTLLSVKYPLTNEVTFIDIGQGDSI
LVREWTGKNLLIDVGGRPFFSSKEHWRRGHHVANAQKTLIPYLKSRGIHT
IDQLLVTHADTDHMGDIEVVAKAIRIKEILTSQGSLSHPSFVRRLRRLKC
HVRVLAAGDQLPIMGSVLQVLYPWQLGDGKNNDSLVLYGRLLNRTFLFTG
DLEKEGENEIIKRYPQLRVDYLKAGHHGSNTSSSAAFLDHIQPKVAFISA
GKNNRYQHPHRETLARLEDRQITYYRTDTQGAIRLTGRTSWHLETVR
>M5005_Spy1326 comFC, COMF operon protein 3
MICLLCQQISQTPISITEIIFLRRISSPICQQCQKSFQKIGKSVCATCCA
NSDIIACRDCLKWENKGYNVNHRSLYCYNAAMKAYFSQYKFQGDYLLRKV
FAVELADVITKYYKGYIPVPVPVSPGCFRERQFNQVSAILEAANVSYLSL
FEKLDNTHQSSRTKKERLLVEKSYRLLKVSNIPDKILIVDDIYTTGSTII
ALRKQLAKVANSDIKSLSIAR
>M5005_Spy0890 ddh, D-lactate dehydrogenase
MKLKLYNVRGEEAVLAKKWADDNGIEISLTESPLTPETVKEAEGFDGIAN
AQIGPLDDAIYPLLKEMGIKQIAQHSASVDMYNLDLATENDIIITNVPSY
SPESIAEFTVTIVLNLIRHVELIRENVKKQNFTWGLPIRGRVLGDMTVAI
IGTGRIGLATAKIFKGFGCKVVGYDIYQSDAAKAVLDYKESVEEAIKDAD
LVSLHMPPTAENTHLFNSDLFKSFKKGAILMNMARGAVIETQDLLDALDA
GLLSGAGIDTYEFEGPYIPKNFEGQEITDSLFKALINHPKVIYTPHAAYY
TDEAVKNLVEGALNATVEIIKTGTTTTRVN
>M5005_Spy0428 drrA, daunorubicin resistance ATP-binding protein
MVMIEVSHLQKNFSKTIKEPGLKGALKSFVHPQREIFEAVKDLSFEVPKG
QILGFIGANGAGKSTTIKMLTGILKPTSGYCRINGKIPQDNRQYYVRDIG
AVFGQRTQLWWDLALQETYVVLKEIYDVPEKAFRKRMDFLNEVLDLNEFI
KDPVRTLSLGQRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAIT
QINQEEETTILLTTHDLSDIEQLCDRIIMIDKGQEIFDGTVTQLKQSFGK
MKSLSFELKPGQEQVVSQFMGLPDITVERHEFSLDIQYDSSRYQTADIIQ
KTMADFAVRDVKMTDVDIEDIVRRFYRKEL
>M5005_Spy0725 elaC, metal-dependent hydrolase
MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQRQILETT
IKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKT
YVLTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFEVYAERLAHTIFCM
GYRVVQKDLEGTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKD
YISAPKKGKIITIIGDTRKTSASVKLAKDADVLVHESTYGKGDERIARNH
GHSTNMQAAQIAHEAGAKRLLLNHVSARFLGRDCRQMEKDAATIFENVKM
VQDLEEVII
>M5005_Spy0390 era, GTP-binding protein homolog
MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMGIYTTE
TEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKG
DDMIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFHSQMDFKEVVPIS
ALEGNNVPTLIKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHL
TQQEVPHSVAVVVESMKRDEETDKVHIRATIMVERDSQKGIIIGKQGAML
KKIGKMARRDIELMLGDKVYLETWVKVKKNWRDKKLDLADFGYNEKEY
>M5005_Spy0748 estA, acetyl esterase
MASIAIEYHSVVLGMERKVNVIYPDQSEIPKKDQGDKDIPVLYLLHGMGG
NENSWQKRTAIERLLRHTNLIVVMPSTDLGWYTDTAYGLNYYRALSQELP
QVLAAFFPNMTQKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALD
FSPETLLEGKLGELAYWQGVFGQFDDPDLDKHYLKNMVAESDGKTKFYAW
CGYEDFLFATNEKAIADFQAQGLDIDYHKGHGKHEWYYWNQQLEVLLEWL
PINYQKEERLS
>M5005_Spy1492 fabK, enoyl-[acyl-carrier protein] reductase (NADH)
MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGGNAPKEV
VKANIDRVKAITDRPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPG
KYMERLHQAGIIVVPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTT
MSLVRQVVEAVSIPVIAAGGIADGHGAAAAFMLGAEAVQIGTRFVVAKES
NAHQNFKDKILAAKDIDTVISAQVVGHPVRSIKNKLTSAYAKAEKAFLIG
QKTATDIEEMGAGSLRHAVIEGDVVNGSVMAGQIAGLVRKEESCETILKD
IYYGAARVIQNEAKRWQSVSIEK
>M5005_Spy1857 guaB, inosine-5'-monophosphate dehydrogenase
MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTLNIPIIT
AAMDTVTGSKMAIAIARAGGLGVIHKNMSITEQAEEVRKVKRSENGVIID
PFFLTPEHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISD
YNAPISEHMTSEHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGL
ITIKDIEKVIEFPHAAKDEFGRLLVAAAVGVTSDTFERAEALFEAGADAI
VIDTAHGHSAGVLRKIAEIRAHFPNRTLIAGNIATAEGARALYDAGVDVV
KVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAREYGKTIIADGGIKYSG
DIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRGMGSIAAMK
KGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
VGAGDIQELHENAQFVEMSGAGLIESHPHDVQITNEAPNYSVH
>M5005_Spy0723 hflX, GTP-binding protein
MIETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMASFSQKR
ERYDSKTFIGSGKLDEIKAIVEADEIDAVIVNNRLTARQNANLEAVLEVK
VIDRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGIMLSRQAGG
IGSRGPGESQLELNRRSIRHQIADIERQLTQVEKNRQTIRDRRVGSDTFK
IGLIGYTNAGKSTIMNLLTDDSHYEANELFATLDATTKQLYLENQFQATL
TDTVGFIQDLPTELVAAFKSTLEESKYVDLLLHVIDASDPNHSEQEKVVL
NLLKELDMLNIPRLAIYNKVDIAEQFTATAFPNIRISARSKDSKILLRRL
IIDQIRDQFVPFRIKVHQDKAYKLYDLNRVALLDHYTFDQEIEDISGYIS
PKQQWRLDDFYE
>M5005_Spy1472 hit, bis(5'-nucleosyl)-tetraphosphatase(asymmetrical)
MENCIFCSIIQGDIPSSKVYEDEQVLAFLDISQTTKGHTLVIPKQHVRNL
LEMTAETASHLFARIPKIARAIQSATGATAMNIINNNEALAGQTVFHAHV
HLVPRYNEEDGISIQYTTHEPDFPVLEKLARQINQEVSS
>M5005_Spy0317 hlyX, putative hemolysin
MEDPVSQPLVIQFLLLVVLTLLNAFFSASEMALVSLNRSRVEQKAADGDK
KYARLLRVLEEPNHFLSTIQVGITFISLLSGASLSASLGKVISGWLGNSA
TARTAGTIISLVFLTYVSIVLGELYPKRIAMNLKDKLAIVSAPIIIGLGR
LVSPFVWLLSASTNLLSRLTPMTFDDADEQMTRDEIEYMLSKSEATLDAE
EIEMLQGVFSLDEMMAREVMVPRTDAFMIDINDDPLENIQEILKQSFSRI
PVYDVDKDKIIGLIHTKRLLESGFRQGFDQINMRKMLQEPLFVPETIFVD
DLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLEEIVGEIDDETDKAEQF
VHEIGDNTYIVVGTMTLNEFNDYFDTELESDDVDTIAGFYLTGIGTIPSQ
EQKEAYEIDNKDKHLVLINDKVKDGRITKLKLILSNIEQIIEED
>M5005_Spy0524 idnO, gluconate 5-dehydrogenase
MENMFSLQGKIALITGASYGIGFEIAKAYAQAGATIVFNDIKQELVDKGL
AAYRELGIEAHGYVCDVTDEAGIQQMVSQIEDEVGAIDILVNNAGIIRRT
PMLEMAAEDFRQVIDIDLNAPFIVSKAVLPSMIAKGHGKIINICSMMSEL
GRETVSAYAAAKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLR
ERQADGSRHPFDQFIIAKTPAARWGTTEDLAGPAVFLASDASNFVNGHIL
YVDGGILAYIGKQP
>M5005_Spy1723 isp, immunogenic secreted protein
MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNSTSSTDQPTTADTDTDDE
SETPKKDKKSKETASQHDTQKDHKPSHTHPTPPSNDTKQTDQASSEATDK
PNKDKNDTKQPDSSDQSTPSPKDQSSQKESQNKDGRPTPSPDQQKDQTPD
KTPEKGPEKATDKTPEPNRDAPKPIQPPLAAAPVFIPWRESDKDLSKLKP
SSRSSAAYVRHWTGDSAYTHNLLSRRYGITAEQLDGFLNSLGIHYDKERL
NGKRLLEWEKLTGLDVRAIVAIAMAESSLGTQGVAKEKGANMFGYGAFDF
NPNNAKKYSDEVAIRHMVEDTIIANKNQTFERQDLKAKKWSLGQLDTLID
GGVYFTDTSGSGQRRADIMTKLDQWIDDHGSTPEIPEHLKITSGTQFSEV
PVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVDRYMGNGGDW
QRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILISE
SNVMGLGTISYRTFTAEQASLLTYVVGDKLPRP
>M5005_Spy1531 isp2, immunogenic secreted protein
MNKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSDSSSKEE
NNKNAAPTTSDKTDQGPLDASAETNSNSLVNADDKKRSDSSQSAIGSSDN
KAEAENQVDDKSTDHSKSTDHSKPTDQPKPSPSKVDTAPASSLSKQLPEA
RTPIQSLSPYVSDLDLSEIDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYG
IKADQIDSYLKSTGIAYDSTRINGEKLLQWEKKSGLDVRAIVAIAMSESS
LGTQGIATLLGANMFGYAAFDLDPTQASKFNDDSAIVKMTQDTIIKNKNS
NFALQDLKAAKFSRGQLNFASDGGVYFTDTTGSGKRRAQIMEDLDKWIDD
HGGTPAIPAELKVQSSASFASVPAGYKLSKSYDVLGYQASSYAWGQCTWY
VYNRAKELGYQFDPFMGNGGDWKYKVGYALSKTPKVGYAISFAPGQAGAD
GTYGHVSIVEDVRKDGSILISESNCIGLGKISYRTFTAQQAEQLTYVIGK
SKN
>M5005_Spy1803 lmrP, multidrug resistance protein B
MQEFLNLPKQIQLRQLVRFVTITLGSSIFPFMAMYYTTYFGTFWTGLLMM
ITSLMGFVGTLYGGHLSDALGRKKVIMIGSVGTTLGWFLTILANLPNAAI
PWLTFAGILLVEIASSFYGPAYEAMLIDLTDESNRRFVYTINYWFINIAV
MFGAGLSGLFYDHHFLALLVALLLVNVLCFGVAYYCFDETRPETHAFDHG
KGLLASFQNYRQVFHDRAFVLFTLGAIFSGSIWMQMDNYVPVHLKLYFQP
TAVLGFQVTSSKMLSLMVLTNTLLIVLFMTVVNKLTEKWKLLPQLVVGSL
LFTLGMLLSFTFTQFYAIWLSVVLLTFGEMINVSASQVLRADMMDHSQIG
SYTGFVSMAQPLGAILASLLVSVSHFTGPLGVQCLFAVIALLGIYFTVVS
AKMKKV
>M5005_Spy1600 lppC, acid phosphatase
MKSKKVVSVISLTLSLFLVTGCAKVDNNKSVNLKPATKQTYNSYSDDQLR
SRENTMSVLWYQRAAETQALYLQGYQLATDRLKEQLNKPTDKPYSIVLDI
DETVLDNSPYQAKNVLEGTGFTPESWDYWVQKKEAKPVAGAKDFLQFADQ
NGVQIYYISDRSTTQVDATMENLQKEGIPVQGRDHLLFLEKGVKSKESRR
QKVKETTNVTMLFGDNLLDFADFSKKSQEDRTALLSDLQEEFGRRFIIFP
NPMYGSWEGAIYKGEKLDVLKQLEERRKSLKSFK
>M5005_Spy0450 mefE, macrolide-efflux protein
MNNRKKNIQYLVYSKVIYRIGDVMFDFANNTFLAGLNPASLSLVAVYQSL
ESVIGVLFNLFGGVIADSFKRKKIIITTNILCGTACLVLSFLTKEQWLVY
AIVLTNVILAFMSAFSSPSYKAFTKEIVKKDSISQLNSLLETTSTVIKVT
VPMVAIFLYKLLGIHGVLLLDGLSFLIAALLISFILPVNDEVVIKEKVTI
REIFNDLKIGFKYVYSHKSIFIITVLSALVNFFLAAYNLLLPYSNQMFGE
ISTGLYGTFLTAEAIGGFIGAILSGFVNKELSSMRLILFLSLSGLMLMLA
PPFYIMFHNAIILALSPALFSLFLSIFNIQFFSLVQKDVDNDFLGRVFGI
IFTITILFMPIGTGFFSVALNPNNSFNLFIIGSCITTLSLVFRILFKKYN
IR
>M5005_Spy0345 metS, methionyl-tRNA synthetase
MKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGHEVFYLTGLD
EHGQKIQTKAKEAGITPQTYVDNMAKDVKALWQLLDISYDTFIRTTDDYH
EEVVAAVFEKLLAQDDIYLGEYSGWYSVSDEEFFTESQLKEVFRDEDGQV
IGGIAPSGHEVEWVSEESYFLRLSKYDDRLVAFFKERPDFIQPDGRMNEM
VKNFIEPGLEDLAVSRTTFTWGVPVPSDPKHVVYVWIDALLNYATALGYR
QANHANFDKFWNGTVFHMVGKDILRFHSIYWPILLMMLDLPMPDRLIAHG
WFVMKDGKMSKSKGNVVYPEMLVERFGLDPLRYYLMRSLPVGSDGTFTPE
DYVGRINYELANDLGNLLNRTVAMINKYFDGTVPAYVDNGTAFDADLSQL
IDAQLADYHKHMEAVDYPRALEAVWTIIARTNKYIDETAPWVLAKEDGDK
AQLASVMAHLAASLRLVAHVIQPFMMETSAAIMAQLGLEPVSDLSTLALA
DFPANTKVVAKGTPIFPRLDMEAEIDYIKAQMGDSSAISQEKEWVPEEVA
LKSEKDVITFETFDAVEIRVAEVKEVSKVEGSEKLLRFRVDAGDGQDRQI
LSGIAKFYPNEQELVGKKLQIVANLKPRKMMKKYISQGMILSAEHGDQLT
VLTVDSSVPNGSIIG
>M5005_Spy1241 mutT, mutator protein (7,8-dihydro-8-oxoguanine-triphosphatase)
MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWFLPGGEI
EAGEGQLQALERELIEELGFSATIGSYYGQADEYFYSRHRDTHFYHPAYL
YEVTAFQAVSKPLEDFNNLGWFSPIEAIAKLKRESHQWGVKEWQKKHHST
N
>M5005_Spy1575 norA, quinolone resistance protein
MEEKLFNKHFVAITVINFIVYMVYYLFTVIIAFVATRELGAQTSQAGLAT
GIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFYMPTISMM
YLVRFLNGFGYGVVSTATNTIVTAYIPARKRGEGINFYGLSTSLAAAIGP
FVGTFMLDNLHIDFRMIIVLCSVLIGCVVVGAFAFPVKNMSLNAEQLAKT
KSWTVDSFIEKKALFITAIAFLMGIAYASVLGFQKLYTSEIHLTTVGAYF
FVVYALIITITRPAMGRLMDAKGDKWVLYPSYLFLAMGLFLLGSVSSGGS
YLLSGALIGFGYGTFMSCGQAASIQGVDEHRFNTAMSTYMIGLDLGLGAG
PYLLGLIKDLALGSGVASFRHLFWLAAVIPLICTLLYLLKTKTRQVVS
>M5005_Spy0872 nox, NADH oxidase H2O-forming
METYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSAD
VIAKLENKDIKRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYY
DRDLTDLMAKNMEEHGIQLAFGETVKEVAGNGKVEKIITDKNEYDVDMVI
LAVGFRPNTTLGNGKIDLFRNGAFLVNKRQETSIPGVYAIGDCATIYDNA
TRDTNYIALASNAVRTGIVAAHNACGTDLEGIGVQGSNGISIYGLHMVST
GLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYDKDSRRILG
AQMAAREDVSMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
ALGAKD
>M5005_Spy1088 obg, GTP-binding protein OBG family
MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGGSVIFRV
DEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGAEDLIVFVPQGTTVRDA
ETGKVITDLVEHGQEVVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEE
RQLELELKILADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLG
MVRTKSGDSFAMADLPGLIEGASQGVGLGTQFLRHIERTRVILHVIDMSA
SEGRDPYEDYVSINNELETYNLRLMERPQIIVANKMDIPEAQENLKAFKK
KLAAQYDEFDDLPMIFPISSLAHQGLENLLEATAELLAKTDEFLLYDESD
LVDEEAYYGFAETEKDFEITRDDDATWVLSGEKLERLFVMTNMERDESIM
KFARQLRGMGVDEALRERGAKDGDPVRIGKFEFEFVD
>M5005_Spy0287 pgdA, GTP-binding protein
MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLN
RQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDAD
EYVSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGI
GTGDVLDAIVENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRV
IASPVAGTTRDAIDTHFTDADGQEFTMIDTAGMRKSGKIYENTEKYSVMR
AMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTID
KDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQRLNKLPDLIKRISESQ
NKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKPPTFVVFVN
EEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK
>M5005_Spy0588 pheT, phenylalanyl-tRNA synthetase beta chain
MGTKIMLVSYKWLKELVDIDVTPAALAEKMSTTGIEVEGIEVPADGLSKL
VVGHVLSCEDVPETHLHLCQVDTGDETPRQIVCGAPNVKAGIKVIVAVPG
ARIADNYKIKKGKIRGMESLGMICSLQELGLSDSIIPKEFSDGIQILPEE
AVPGDAIFKYLDLDDHIIELSITPNRADALSMRGVAHEVAAIYGKSVSFP
QKNLQESDKATSEAIEVAIASDNVLTYASRVVENVKVKPSPQWLQNLLMN
AGIRPINNVVDVTNYVLLYFGQPMHAFDYDKFEDHKIVARAARQGESLVT
LDGEKRDLTTEDLVITVADKPVALAGVMGGQATEIDANSQTVVLEAAVFD
GKSIRKTSGRLNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEGQVL
SGHVQAGQLPTEPVEVSTSLDYVNVRLGTELTFADIQRIFDQLGFGLTGD
ETSFTVAVPRRRWDVSIPADLVEEIARIYGYDKLPTTLPEAGGTAAELTP
TQALRRKVRGLAEGLGLTEIISYALTTPEKAVEFAVAPSHLTELMWPMSV
ERSALRQNMVSGMLDTVAYNVARKQSNLALYEIGKIFEQEANPKEDLPNE
VNHFAFAICGLVAQKDFQTQAQAVDFYHAKGNLDTLFANLNLKVQYVPTK
DLANMHPGRTALILLDEQVIGFVGQVHPGTAKAYSIPETYVAELDMAALE
AALPSDQTFAEITKFPAMTRDVALLLDREVSHQAIVTAIESAGVKRLTSI
KLFDVYEGATIQAGKKSMAYSLTFQNPNDNLTDEEVAKYMEKITKALTEQ
VGAEVR
>M5005_Spy1354 recU, recombination protein
MVNYPHNLIRQKVSSVQKQNKVDFANRGMSFEAAINATNDYYLSRQIAVI
HKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYCGVYKGHYVDFEAKE
TRQKTAMPMKNFHLHQIEHMACVLHQKGICFVLLHFSTLKETYYLPAQAL
ISFYQIDNGSKSMPIDYIRKNGFKVAFGAFPQVPYLNIIEQNFLGGDYN
>M5005_Spy1320 recX, regulatory protein
MKITKIEKKKRLYLIELDNDESLYVTEDTIVRFMLSKDKVLDNDQLEDMK
HFAQLSYGKNLALYFLSFQQRSNKQVADYLRKHEIEEHIIADIITQLQEE
QWIDDTKLADTYIRQNQLNGDKGPQVLKQKLLQKGIASHDIDPILSQTDF
SQLAQKVSQKLFDKYQEKLPPKALKDKITQALLTKGFSYDLAKHSLNHLN
FDQDNQEIEDLLDKELDKQYRKLSRKYDGYTLKQKLYQALYRKGYNSDDI
NCKLRNYL
>M5005_Spy0566 sagE, streptolysin S putative self-immunity protein
MPLSIQCLNLCFLLVTFCPSIPMQAIFGKEDSGYAFNLIGFLRATLIYDI
LALVSIYVLSPQITLSLESIDSKTFFMGLVFCVLIVLIELVFLHGLRCWQ
KKQWLPATFSFVGTTNDWSKIGYPLLLALFEETIYRFLWFNILAFQWHLP
TIIVLIVTSFCYALNHLLMGKSIFYAKLVTGIIYGSIYMLTSQLWLVVIM
HVGGNLLVECLSHLQTKKKKEVT
>M5005_Spy0017 sibA, secreted protein
MKKRILSAVLVSGVTLGAATTVGAEDLSTKIAKQDSIISNLTTEQKAAQN
QVSALQAQVSSLQSEQDKLTARNTELEALSKRFEQEIKALTSQIVARNEK
LKNQARSAYKNNETSGYINALLNSKSISDVVNRLVAINRAVSANAKLLEQ
QKADKVSLEEKQAANQTAINTIAANMAMAEENQNTLRTQQANLVAATANL
ALQLASATEDKANLVAQKEAAEKAAAEALAQEQAAKVKAQEQAAQQAASV
EAAKSAITPAPQATPAAQSSNAIEPAALTAPAAPSAGPQTSYDSSNTYPV
GQCTWGAKSLAPWAGNNWGNGGQWAYSAQAAGYRTGSTPMVGAIAVWNDG
GYGHVAVVVEVQSASSIRVMESNYSGRQYIADHRGWFNPTGVTFIYPH
>M5005_Spy0794 thdF, tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase
MSITKEFDTITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKNLEQVAS
HTINYGHIINPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNE
ILQLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMTI
AVKQLDGSLSQLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREK
TQEFQSLLESLLRTAKRGKILREGLSTAIIGRPNVGKSSLLNNLLREDKA
IVTDIAGTTRDVIEEYVNIKGVPLKLVDTAGIRETDDLVEQIGVERSKKA
LQEADLVLLVLNASEKLTDQDRALLNLSQDSNRIILLNKTDLEQKIELEQ
LPDDYIPISVLTNQNINLIEDRINQLFFDNAGLVEQDATYLSNARHISLI
EKAVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQL
FSQFCLGK
>M5005_Spy0437 vicX, Zn-dependent hydrolase
MNESGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLLAEIDRK
PEDLDAILITHEHSDHIKGVGVMARKYHLDIYANEKTWQLMDECNMLGKL
DASQKHIFQRDKVLTFGDVDIESFGVSHDAIDPQFYRIMKDNKSFVMLTD
TGYVSDRMTGIIENADGYLIESNHDIEILRSGSYPWSLKQRILSDLGHLS
NEDGAGAMIRSLGYNTKKIYLGHLSKENNIKELAHMTMVNQLAMADLAVG
TDFTVHDTSPDTACPLTDI
>M5005_Spy0162 vlg, trans-acting positive regulator Mry
MFLTWENLFLTNQSRRRLKLLVVERSYNNVGNFLKEYFGGFFEIINFDDL
RLTMVDMVSLSSEYDVIVTDMILEQTMDSEILFFNQMAPSVVANRLTDM