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# Streptococcus pyogenes MGAS10394, MGAS10394

>M6_Spy0839 Glutamine amidotransferase, class I
MTKPIIGITANQRLNMALDNLPWSYAPTGFVQAVTQSGGLPLLLPIGDEA
AAKTYVSMVDKIILIGGQNVGPKYYQEEKAAFDDDFSPERDTFELAIIKE
AITLKKPILGICRGTQLMNVALGGNLNQHIDSHWQEAPSDFLSHEMIIEP
DSILYPIYGHKTLINSFHRQSLKTVAKDLKVIARDPRDGTIEAVISTNDA
IPFLGVQWHPELLQGVRDEDLQLFRLFVNDF
>M6_Spy0832 Zn-dependent alcohol dehydrogenases and related dehydrogenases
MLLNVLKTGKIDATRFITHHFKLSEVEKAYETFKHAGANNALKVIIDNDI
S
>M6_Spy0352 Export protein for polysaccharides and teichoic acids
MSTEKKQLTQEELMVQGAAWSTAGNFISRLLGVLYIIPWYIWMGQYAIQA
NALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQTEHSYQLIRSTL
KLMLGLGLIFSAIMYLGSPLFARLSGGDDTLVPIMHSLSLAVFIFPVMSV
IRGIFQGHNNIKPYAVSQIAEQLIRVIWMLLTTFFIMKLGSGDYASAVTQ
STFAAFIGMVASMGVLGYYLWKQGLLAAIFSKPDHTVSIDIKGLLLETLK
ESIPFIVTGSAIQAFQLIDQWTFVNTMTLFTDYSRSQLLVLFGYFNANPA
KITMVLIAVAASIGGVGIALLTENYVKKDMKAAARLIINNIEMLVMFLLP
ALTGAIILARPLYSVFYGASEERAIHLFVAVLFQTLLLALYTLFSPMLQA
LFENRKAIYYFAYGILIKLVLQIPLIYLLHAYGPLLATTIALVVPIYLMY
RRLYQVTHFNRKLLQKRLLLTLIETLLMGLVVFVANWLLGYAFKPTGRLT
SLLYLLIIGGLGMTVYTALTLLTHQLDKLIGSKASRLRQKLGWH
>M6_Spy0331 putative phosphoesterase
MASKTIIVMSDSHGDRDIVQAIKDKYLGQVDAIFHNGDSELNSSDPIWAG
IYVVGGNCDYDTGYPDRLVTQLGTVTIAQTHGHLYHINFTWDKLDYFAQE
VAADICLYGHLHRPAAWQVGQILFMNPGSVTQPRGEINEKLYARVELTDT
QIKVDYFTRDHKLYPSLSKEFKR
>M6_Spy1586 NorA
MLMPFDSNTYIIPLKYIIFCFFCKMFMKIERSSFSMEEKLFNKHFVAITV
INFIVYMVYYLFTVIIAFVATRELGAQTSQAGLATGIYILGTLLARLIFG
KQLEVFGRRLVLRGGAIFYLLTTLAYFYMPTISMMYLVRFLNGFGYGVVS
TATNTIVTAYIPACKRGEGINFYGLSTSLAAAIGPFVGTFMLDNLHIDFR
MIIVLCSVLIGCVVVGAFAFPVKNMSLNAEQLAKTKSWTVDSFIEKKALF
ITAIAFLMGIAYASVLGFQKLYTSEIHLTAVGAYFFVVYALIITITRPAM
GRLMDAKGDKWVLYPSYLFLAMGLFLLGSVSSGGSYLLSGALIGFGYGTF
MSCGQAASIQGVDEHRFNTAMSTYMIGLDLGLGAGPYLLGLIKDLALGSG
VASFRHLFWLAAVIPLICTLLYLLKTKTRQVVS
>M6_Spy0343 Magnesium and cobalt efflux protein
MKSLYYFFRSYINMEDPVSQPLVIQFLLLVVLTLLNAFFSASEMALVSLN
RSRVEQKAADGDKKYARLLRVLEEPNHFLSTIQVGITFISLLSGASLSAS
LGKVISGWLGNSATARTAGTIISLVFLTYVSIVLGELYPKRIAMNLKDKL
AIVSAPIIIGLGRLVSPFVWLLSASTNLLSRLTPMTFDDADEQMTRDEIE
YMLSKSEATLDAEEIEMLQGVFSLDEMMAREVMVPRTDAFMIDINDDPLE
NIQEILKQSFSRIPVYDVDKDKIIGLIHTKRLLESGFRQGFDQINMRKML
QEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLEEIV
GEIDDETDKAEQFVHEIGDNTYIVVGTMTLNEFNDYFDTELESDDVDTIA
GFYLTGIGTIPSQDQKEAYEIDNKDKHLVLINDKVKDGRITKLKLILSNI
EQIIEED
>M6_Spy0157 Fibronectin-binding protein
MVSSYMFVRGEKMNNKIFLNKEASFLAHTKRKRRFAVTLVGVFFMLLACA
GAIGFGQVAYAADEKTVPSHSSPNPEFPWYGYDAYGKEYPGYNIWTRYHD
LRVNLNGSRSYQVYCFNIQSNYPSQKNSFIKNWFKKIEGNGKSFVDYAHT
TKLGKEELEQRLLSLLYNAYPNDANGYMKGLEHLNAITVTQYAVWHYSDN
SQYQFETLWESEAKEGKISRSQVTLMREALKKLIDPNLEATAVNKIPSGY
RLNIFESENEAYQNLLSAEYVPDDPPKPGETSEHNPKTPELDGTPIPEDP
KHPDDNLEPTLPPVMLDGEEVPEVPSESLEPALPPLMPELDGQEVPEKPS
IDLPIEVPRYEFNNKDQSPLAGESGETEYITEVYGNQQNPVDIDKKLPNE
TGFSGNMVETEDTKEPEVLMGGQSESVEFTKDTQTGMSGQTTPQVETEDT
KEPEVLMGGQSESVEFTKDTQTGMSGQTTPQIETEDTKEPEVLMGGQSES
VEFTKDTQTGMSGQTTPQIETEDTKEPEVLMGGQSESVEFTKDTQTGMSG
FSETATVVEDTRPKLVFHFDNNEPKVEENREKPTKNITPILPATGDIENV
LAFLGILILSVLSIFSLLKNKQSNKKV
>M6_Spy0497 Multidrug resistance protein B
MSHHQQTVSKQTIMAIIAIALIGFSGILSETSMNVTFPTLMSVYQLPLNS
LQWMTTIYLLAVAIMMTTSATLKKNVRERPLFFMATGLFTFGTILAVLTQ
SFAIMLLARIFQGIGTGLVMPQMFNIILERVPMHKVGLFMGFAGLIISLA
PAFGPTYGGFMISHFSWQWIFICILPVPLIAGILAYYYLEDSPVSEKVPF
DWLAFIALSISLTSALLAITSLENASVNLYYLGLFILSFVLFLYKNLTAK
QPFLDIRILKIPSLTFGLIPFFVFQLINLGINFLTPNFIVMEKIANSSQA
GMVLLPGTLLGALLAPAFGKLYDQKGARLSLYLGNALFSLSLIIMTLQTR
HFMPLPFTLLYILFTFGRNMGFNNSLATAIRELPAEKNADATAIFQMMQQ
FAGALGTTMASLIANSQPEFTSGVQSVYLLFTIFALLDFIFFFAMFYHLG
KKGLA
>M6_Spy1435 Aldo/keto reductase family
MMVTTVKMTSGYEIPVLGFGTYQAADGEEAYQSTLAAIKADYRHIDTAAI
YKNEESVGRAIKDSGVLREDLFITTKLWNDAHSYEGAKDALAASLDRLGL
DYVDLYLIHWPNPKALRNTWKEANAQAWQYMEEAVEAGLIKSIGVSNFMV
HHLEALQETAKITPAINQIRLAPGCYQKEVVDYCKANEILLEAWSPLGQG
EIFDNETMQQLANKYDKTVAQVALAWSLAEGFIPLPKSVHDERIKENMAI
FDVSLTPEDKKTIRYLSGMSAIPNPDTTSF
>M6_Spy0456 Daunorubicin resistance transmembrane protein
MGAFVAYYLWKAVFDSSKQSLINGFTLSDMTFYIIMSFVTTLLTKSDSSF
MIGEEVKDGSIIMRLLRPVHFAASYLFMEIGFRWIVLMSVGFPFLMVLSG
IKVMAGLSILQVLASSCLYLVSLLLAFLINFYFNICFGFSAFVFKNLWGS
NLLKNALVAFMSGSLIPLAFFPKMVSIVLSFLPFSSLVYTPVMIVIGKYS
LSQIMEALSLQIFWLLVMVVLSQVIWKKVQYHLTIQGG
>M6_Spy0077 Autolysin
MKKFHRFLVSGVILLGFNGLVPTMPSTLISQQENLVHAAVLGDNYPSKWK
KGNGIDSWNMYIRQCTSFAAFRLSSANGFQLPKGYGNACTWGHIAKNQGY
PVNKTPSIGAIAWFDKNAYQSNAAYGHVAWVADIRGDTVTIEEYNYNAGQ
GPERYHKRQIPKSQVSGYIHFKDLSSQTSHSYPRQLKHISQASFDPSGTY
HFTTRLPVKGQTSIDSPDLAYYEAGQSVYYDKVVAAGGYTWLSYLSFSGN
RRYIPIKEPAQSVVQNDNTKPSIEVGDTVTFPGVFRVDQLVNNLIVNKEL
AGGDPTPLNWIDPTPLDETDNQGKVLGDQILRVGEYFTVTGSYKVLKIDQ
PSNGIYVQIGSRGTWVNADKANKL
>M6_Spy0840 Redox-sensitive transcriptional regulator
MVIDKSIPKATAKRLSLYYRIFKRFHADQVEKASSKQIADAMGIDSATVR
RDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTNVILVGCGNIGRALL
HYRFHDRNKMQIAMGFDTDDNALVGTKTADNIPVHGISSVKERIANTDIE
TAILTVPSIHAQEVTDQLIEAGIKGILSFAPVHLQVPKGVIVQSVDLTSE
LQTLLYFMNQNHLD
>M6_Spy0931 Nucleoside-binding protein
MNKKFISLGLASVAVLSLAACGNRGASKGGAAGKTDLKVAMVTDTGGVDD
KSFNQSAWEGLQSWGKEMGLQKGTGFDYFQSTSESEYATNLDTAVSGGYQ
LIYGIGFALKDAIAKAAGDNEGVKFVIIDDIIEGKDNVASVTFADHEAAY
LAGIAAAKTTKTKTVGFVGGMEGTVITRFEKGFEAGVKSVDDTIQVKVDY
AGSFGDAAKGKTIAAAQYAAGADVIYQAAGGTGAGVFNEAKAINEKRSEA
DKVWVIGVDRDQKDEGKYTSKDGKEANFVLASSIKEVGKAVQLINKQVAD
KKFPGGKTTVYGLKDGGVEIATTNVSKEAVKAIKEAKAKIKSGDIKVPEK
>M6_Spy0202 Metal-dependent hydrolase
MTKVQDITRESWILNTFPEWGTWLNEEIEQEVVPADNFAMWWLGNCGIWI
KTPGGANVVMDLWSNRGKATKQVKDMVRGHQMANMAGARKLQPNLRAQPM
VIDPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLNHVKFVGPYECGE
VWKNWGVPKDRIMILKPGDSFEFKDIKITAVESFDRTCLVTLPIQGADAQ
DGDLAGLAITDDDMARKAVNYIFETPGGTIYHGADSHFSNYFAKHGRDYD
IDVVLNNYGENPIGIQDKMTSVDLLRMAENLRAKVVIPVHYDIWSNFMAS
TDEILELWKMRKERLQYDFHPFIWEVGGKYTYPQDQNRIEYHHPRGFDDC
FLEDSNIQFKALL
>M6_Spy1606 Zn-dependent hydrolase
MTNISLKPNEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFPEDDLL
GIDYVIPDYSYIVDNLDRVKALVITHGHEDHIGGIPFLLKQANIPIYAGP
LALALIRGKLEEHGLWREATVYEINHNTELTFKNMSVTFFKTTHSIPEPV
GIVIHTPQGKIICTGDFKFDFTPVGDPADLQRMAALGEEGVLCLLSDSTN
AEIPTFTNSEKVVGQSILKIIEGIHGRIIFASFASNIYRLQQAAEAAVKT
GRKIAVFGRSMEKAIVNGIELGYIKVPKGTFIEPSELKNLHASEVLIMCT
GSQGESMAALARIANGTHRQVTLQPGDTVIFSSSPIPGNTTSVNKLINTI
QEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVHGEYRMQKV
HAGLAMDIGIPKENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
DIGAAVLRDRRDLSEDGVVLAVATVDFNTQMILAGPDILSRGFIYMRESG
DLIRESQRVLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPII
IPMVLTPDKH
>M6_Spy1510 ABC transporter permease protein
MISYLKADLFRIRQERLALFSCMLLVVIAVGVAYSFRKTPNQVIMIQIIN
IITDFVTLFFLTPARIFFSDDYNYRTINNVVVKQQNRTLIIIYKLLVSFG
LSLLFISLTYLLSALAFHLFTGQAYYGIVIDRMIKQLPFYIAIIALCQFL
FNILRKTYQSITAYILYVLLFDKVSATLANHFFKLDISPVLMFKHLSLSL
GDKHLSSTSILVAFGLTLCYLLGNVFLFSKRELK
>M6_Spy0536 dGTP triphosphohydrolase
MVNCNFITLLSISKLVCLFYQFLLILSIFDIIKIMNEKVFRDPVHNYIHI
DNPLIYDLINTKEFQRLRRIKQVPTTAFTFHGAEHSRFSHCLGVYEIARR
VTAIFEEKYADIWNKDESLVTMTAALLHDIGHGAYSHTFEALFHTDHETF
TQEIITNPETEINAILVRHAPDFPDKVASVINHTYPNKQVVQLISSQIDC
DRMDYLLRDSYFSAANYGQFDLMRILRVIRPVEDGIVFEHSGMHAVEDYI
VSRFQMYMQVYFHPASRAVELILQNLLKRAQHLYPKQQAYFQKTAPGLIP
FFEKKANLADYIALDDGVMNTYFQVWMASEDHILSDLASRFINRKILKSV
TFDQDSRGELERLRQLVESVGFDPDYYTGIHINFDLPYDIYRPELENPRT
QIEMMQKDGSLAELSQLSPIVKALTGTTYGDRRFYFPKEMLELDDLFAPS
KETFMSYISNGHFHFSQ
>M6_Spy1166 Macrolide-efflux protein
MEKYNNWKLKFYTIWAGQAVSLITSAILQMAIIFYLTEKTGSAMVLSMAS
LLGFLPYAVFGPAIGVLVDRHDRKKIMIGADLIIAAAGSVLTIVAFYMEL
PVWMVMIVLFIRSIGTAFHTPALNAVTPLLVPEEQLTKCAGYSQSLQSIS
YIVSPAVAALLYSVWELNAIIAIDVLGAVIASITVAIVRIPKLGDRVQSL
DPNFIREMQEGMAVLRQNKGLFALLLVGTLYMFVYMPINALFPLISMDYF
NGTPVHISITEISFASGMLIGGLLLGLFGNYQKRILLITASIFMMGISLT
ISGLLPQSGFFIFVVCCAIMGLSVPFYSGVQTALFQEKIKPEYLGRVFSL
TGSIMSLAMPIGLILSALFADRIGVNHWFLLSGTLIICIAIVCPMINEIR
KLDLK
>M6_Spy0928 Nucleoside transport system permease protein
MVNKMSLVTIFALLVSSMLIYATPLIFTSIGGTFSERSGVVNVGLEGIMV
MGAFSGIVFNLEFAETFGKATPWIAVLVGGIVGLIFSLIHAVATINFRAD
HIVSGTVLNLLAPSFAVFLVKAMYGKGQTDNIQQSFGKFDFPGLSQIPVI
GDIFFKNTSLIGYFAIAFSFFAWFLLYKTRFGLRLRSVGEHPQAADTLGI
NVYLMKYYGVMISGFLGGIGGAVYAQSISVNFAVTTILGPGFIALAAMIF
GKWNPVGAMLSSLFFGLSQSLAVIGAQLPLLEKIPTVYLQIAPYMVTIII
LAAFFGQAVAPKADGINYIKSK
>M6_Spy0387 Phosphohydrolase (MutT/nudix family protein)
MKFEEKTLKRQTVFDGHIFKVVVDDVELPNNLGQSKRELIFHRGAVAVLA
ITPERKILLVKQYRKAIERVSYEIPAGKLEIGEEGSKLKAAARELEEETA
YTGTLTFLYEFYTAIGFCNEKITLFLATDLTQVANPKPQDDDEVIEVLEL
TYQECMDLVAQGKLADAKTLIALQYYALHFGGEQ
>M6_Spy1875 Inosine-5'-monophosphate dehydrogenase
MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTLNIPIIT
AAMDTVTGSKMAIAIARAGGLGVIHKNMSITEQAEEVRKVKRSENGVIID
PFFLTPEHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISD
YNAPISEHMTSEHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGL
ITIKDIEKVIEFPHAAKDEFGRLLVAAAVGVTSDTFERAEALFEAGADAI
VIDTAHGHSAGVLRKIAEIRAHFPNRTLIAGNIATAEGARALYDAGVDVV
KVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAREYGKTIIADGGIKYSG
DIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRGMGSIAAMK
KGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
VGAGDIQELHENAQFVEMSGAGLIESHPHDVQITNEAPNYSVH
>M6_Spy0370 Methionyl-tRNA synthetase
MMKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGHEVFYLTGL
DEHGQKIQTKAKEAGITPQTYVDNMAKDVKALWQLLDISYDTFIRTTDDY
HEEVVAAVFEKLLAQDDIYLGEYSGWYSVSDEEFFTESQLKEVFRDEDGQ
VIGGIAPSGHEVEWVSEESYFLRLSKYADRLVAFFKERPDFIQPDGRMNE
MVKNFIEPGLEDLAVSRTTFTWGVPVPSDPKHVVYVWIDALLNYATALGY
GQANHANFDKFWNGTVFHMVGKDILRFHSIYWPILLMMLDLPMPDRLIAH
GWFVMKDGKMSKSKGNVVYPEMLVERFGLDPLRYYLMRSLPVGSDGTFTP
EDYVGRINYELANDLGNLLNRTVAMINKYFDGTVPAYVDNGTAFDADLSQ
LIDAQLADYHKHMEAVDYPRALEAVWTIIARTNKYIDETAPWVLAKEDGD
KAQLASVMAHLAASLRVVAHVIQPFMMETSAAIMAQLGLAPVSDLSTLAL
ADFPANTKVVAKGTPIFPRLDMEAEIDYIKAQMGDSSAISQEKEWVPEEV
ALKSEKDVITFETFDAVEIRVAEVKEVSKVEGSEKLLRFRVDAGDGQDRQ
ILSGIAKCYPNEQELVGKKLQIVANLKPRKMMKQYISQGMILSAEHGDQL
TVLTVDPSVPNGSIIG
>M6_Spy0415 GTP-binding protein era
MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMGIYTTE
TEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKG
DDMIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPIS
ALEGNNVPTLIKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHL
TQQEVPHSVAVVVESMKRDEETDKVHIRATIMVERDSQKGIIIGKQGAML
KKIGKMARRDIELMLGDKVYLETWVKVKKNWRDKKLDLADFGYNEKEY
>M6_Spy0327 Integral membrane protein
MNDHVIYTQSDVGLNQFFAKIYSLVGMGVGLSAFVSYLMLYPFRENLISI
LVNQPMIYYGAAIIELILVFVASGAARKNTPAALPIFLIYSALNGFTLSF
IIVAYAQTTVFQAFLSSAAVFFAMSIIGVKTKRDMSGLRKAMFAALIGVV
VASLINLFIGSGMMSYVISVISVLIFSGLIASDNQMIKRVYQATNGQVGD
GWAVAMALSLYLDFINLFISLLRIFGRND
>M6_Spy0582 SagE
MPLSIQCLNLCFLLVTFCPSIPMQAIFGKEDSGYAFNLIGFLRATLIYDI
LALVSIYVLSPQITLSLESIDSKTFFMGLVFCVLIVLIELIFLHGLRCWQ
KKQWLPATFSFVGTTNDWSKIGYPLLLALFEETIYRFLWFNILAFQWHLP
TIIVLIVTSFCYALNHLLMGKSIFYAKLVTGIIYGSIYMLTSQLWLVVIM
HVGGNLLVECLSHLQTKKKKEVT
>M6_Spy0763 MutT
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECA
RREILEETHLTVTEMAFKGIITFPEFTPGHDWYTYVFKVTGFEGDLISDE
ESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQL
MDKSVTFY
>M6_Spy1471 Guanine-hypoxanthine permease
MEKFFKLSENGTTVSTEIMAGLTTFFAMSYILFVNPSILGAAGMPSNAVF
LATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFALGFSWQEAL
AMVFICGLFNIFITVTKFRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNA
NIITFSISAENIVMVNGVEPAKASAKTFADGLLFVDANGGVVPTISSFTD
SSVLLAIFGLLLTTALVIRNFRGAILIGIVATTLVGIPLGIVDVSNLNFG
ISHIGEAWTELGTTFLAAFDGLSSLFSDSSRLPLVFMTIFAFSLSDTFDT
IGTFIGTGRRTGIFSQDDENALENSIGFSSKMDRALFADAIGTSIGALVG
TSNTTTYVESAAGIAEGGRTGLTAVSTAVCFLLSILLLPLVGIVPAAATA
PALIVVGVMMVSSFLDVNWSKFADALPAFFAAFFMALCYSISYGIAAAFI
FYCLVKVVEGKTKDIHPIIWGATFLFIVNFIILTIL
>M6_Spy0416 Phosphohydrolase (MutT/nudix family protein)
MAIMRKNTNIVKRDHMPHDYISYIRSKVGHDKIILNFAGGILTNDDSKVL
MQLRGDKKTWAIPGGTMELGESSLETCKREFLEETRIEVEAVRLLNVYTH
FEEVYPNGDAVQTIVFIYELTAVSDMAIDNFHNEETLKLQFFSHEEIAEL
ESVSAKHRLMLEEYFSDSFAMGH
>M6_Spy1138 Phage Prohead Protease
MDKILELREKRAKVWDKAKNFLDSCRDEKGMISQEDSEHYDKLEQEVVDL
GKEIDRLERQERIERELSQATSAAIVSQPRTDAGGDEKTGTASTVYNQSF
WKNVRQKNFFDVNNTLNIGNDGQGGYLVPDEYENRLIKALEEENFFRRLA
TIIKTSNGERKIPVVTGHGTAAWMDENGTYPESEETFGQVTLGAYKVGTA
IKISEELIHDSVFDLESYMAEEFARRIGSKEEEAFLIGDGSGKPTGVFTT
VTEGVTSTGANITFDDVMDLYHSLKSPYRKNSVWILNDSTIKALRKLKDN
NGNYIWQPSVQAGVPDMILNRPYYTSSYAPEIASGQKVLAFGDFSHYWIS
DRQGRSFKRLNELYATSGQVGFLGSQRVDGKLVLPEAVKVLTMKG
>M6_Spy0362 Hypothetical membrane associated protein
MTEDQATILILGVYGIILAVFSLSALLCLIANWRLFKRAGYKGWHSLIPF
YAGFVKHKITFGEDNKWFYFIGWVIAIYYYYVHFCYVRAFGGPKGLAVFG
LFFPGLASLIVAFGKTYTTQECHPVPHLLN
>M6_Spy0162 Hypothetical protein
MKRCNKYLFTSLLAASMLFSSYKSVHAHDNIDEEGKVHLYWQGNYYVDNY
VDYTKKLVDNDKNIEWTVTFNSTKEQWVYPDFSVFLPKGVKAPKEITYEH
HYGNGTVHSETRSNTQWHYNWENQQTNFNQEFDKFPGYTGWSTSLDKFYK
LKNDGKFSHVLVDTYGRQSHTYFSHKMVWKFKTELEDNYKDKWNKLPFIA
GIKQNNPLAASFPSYKGEFGE
>M6_Spy0773 Acetyl esterase
MANIAIEYHSVVLGMERKVNVIYPDQSEIPKKDQGDKDIPVLYLLHGMGG
NENSWQKRTAIERLLRHTNLIVVMPSTDLGWYTDTAYGLNYYRALSQELP
QVLAAFFPNMTQKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALD
FSPETLLEGNLGELAYWQGVFGQFDDPDLDKHYLKNMVAESDGKTKFYAW
CGYEDFLFATNEKAIADFQAQGLDIDYHKGHGKHEWYYWNQQLEVLLEWL
PINYQKEERLS
>M6_Spy1462 tRNA (m(7)G46) methyltransferase
MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIEVGSGKG
GFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVSNVKLLRVDGSSL
TNYFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIH
FKTDNRGLFEYSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNK
GQVIYRVEANF
>M6_Spy1109 O-methyltransferase
MVKSYSKTANHNMRRPVVKEELVHYMRTRQKQITGFLAELEQFARQENIP
IIQPEVVAYFRFLLQSLQPKHILEIGTAIGFSALLMAENAPDATIVTIDR
NREMIDFAKANFAKYDSRQQIRLLEGDAADILSTLEGNFDFVFMDSAKSK
YIVFLPEILRLLKVGGVVILDDVFQGGDITKPIEDIRRGQRTIYRGLQSL
FDATLTHPNLTTSLVPLSDGLLMIRKNQADIVLPD
>M6_Spy1017 unknown phage protein
MVIEIFGPEFRKKLLEDLIALNMEAIKIAQTKNAKSIEWITMKRLEKETG
WGRTKLTQWREQGKFNFKRSSENGKVLYDLADVNRFLRTSGYEKGETT
>M6_Spy0989 Holin
MIINLTSLIHLFGDLVRTVEIHVFTLFVCFDIITGLTKGITNKRANSTKG
LSGIIKHFLVVLLVYTVYPYLILLGAKPLAVAFVLFFIACYGISIVENWG
QLGLPMPSFVRSFFEKLKRDTDQFDIATIKIDKTGVKVEAPQVDLKQKEE
E
>M6_Spy0784 Hypothetical membrane associated protein
MTYTSLKSPENQDYIYDLNIAHLYGNLMNTYGDNGNILMLKYVAEKLGAR
VTVDIVSINDTFEQDDYDIVFFGGGQDYEQSIVAKDLPSKKAALADYIAN
NKVALAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKI
HNDEFNETYYGFENHQGRTFLSGDEKPLGRVVYGNGNNKEDQTEGVHYKN
VYGSYFHGPILSRNVNLAYRLVTTALKKKYGSAISLPSYDDILKQEITEE
YADLKSKASFNKV
>M6_Spy0572 DNA gyrase related protein
MKGMNYQDYIWDLGGTLLDNYELSTQAFVQTLAFFSLPGDHDAVYQKLKE
STAIAVATFAPNEPEFLHVYRLREADKLAQPIWCLGAKEILEKIATSGSR
NFLISHRDCQVNQLLEQAGLLIYFTEVVTASNGFARKPNPESLFYLKEKY
DIDSGLVIGDRLIDKQAGQAAGFNTLLVDGRKNLLEIVT
>M6_Spy0629 AmrA
MINPSKQNQTIFLWNMLGSLSTAVISVILLMVVTRLLTSADSDIYAFAYS
FANMMVVVGLFQVRNYQATDINEKYSFSQYLVARLMTCLLMLAITVIYLT
LTKTDSYKSTIVFLVCFYRSTDAFSDLYQGMFQQHERLDIAGKSLAYRNT
LIFMVYTAIILYSKNLTLALVAVCIVSLVFIMYYDIGHSKKFQKLMFSEL
LSNISFQNSLKLLKESFPLFLNGFLIIYIYTQPKYAIELMTTLGEVALGS
QTIFNILFMPAFVMNLLILFFRPHITQMAIALIRGQIKEFNKIQVQLFAY
LGVFSLIVLVGSGLFGIPFLSILYGTNLTDYWVDFMLIMLGGSIGSFATV
IDNILTAMRKQQLLLIPYTGGFLISLLITNLFVMKYHILGAALSFLITML
VWLGLSIMIYLFIMNRFKKGRVNATIYD
>M6_Spy1065 Hypothetical protein
MTIYSHTYETRPNHSAKAMSSGTLNVLATPALVAFMENASYLFTQEQLDS
DFTTVGSEIAIQHLAASAIGDPVTIIITALKEEGRKYDFRLEAFVGEQLI
GKACHTRVRVNSKHFMAKVAE
>M6_Spy0383 Short chain dehydrogenase
MTKVVLVTGCASGIGYAQARYFLRQGYHVYGVDKSDKPDLNGNFHFIKLD
LSSELSPLFKVVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINFFAT
VKLTRHYLRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQ
LALDYAKDQIHIFGIAPGAVKTAMTASDFEPGGLADWVARETPIGRWTEP
DEVAELSGFLASGKARSMQGEIVKIDGGWTLK
>M6_Spy1377 Peptidyl-prolyl cis-trans isomerase
MEESMDAKLKYKAKKIKMVFFDIDDTLRVKDTGYMPESIQRVFKALKAKG
ILVGIASGRARYGVPQEVQDLHADYCVKLNGAYVKDDAKTIIFQAPIPAD
VVVAYKKWADDMGIFYGMAGRHEAVLSARNDMISNAIDNVYAQLEVCPDY
NEYHDVYQMWTFEDKGDGLQLPAELAEHLRLVRWHDNSSDVVLKGTSKAL
GVSKVVDHLGLKPENILVFGDELNDLELFDYAGISIAMGVSHPLLQEKAD
FITKKVEEDGILYALEELGLIDKELQFPQLDLENHTGPKVTIKTNHGDMT
LVLFPDHAPKTVANFLGLAKEGYYDGIIFHRIIPEFMIQGGDPTGTGMGG
QSIYGESFEDEFSDELYNLRGALSMANAGPNTNGSQFFIVQNSKIPYAKK
ELERGGWPTPIAAAYAENGGTPHLDRRHTVFGQLVDETSFQVLDLIAGVE
TGAQDKPKEDVIIETIEVFD
>M6_Spy0929 Nucleoside transport system permease protein
MVQFIRRKVMSKNAQKIAVPLISVLLGFLLGAIIMVIFGYDPIWGYEGLF
QIAFGSVKNIGEIFRSMGPLILIALGFTVASRAGFFNVGLSGQALAGWIS
AGWFALLNPDMPCPLLILMTALIGMIAGGIAGAIPGILRAYLGTSEVIVT
IMMNYIILYVGNAIVQRGYPESVKQSIDSTIQVSDNASYQTHWLSALTNN
SRINIGIFFAIIAIALIWFLLNKTTLGFEIRSVGLNPHASEYAGMSSKRT
IILSMIISGALAGLGGVVEGLGTFENVFVQGSSLAVGFDGMAVSLLAANS
PLGIFFSSFLFGVLNIGAPGMNIAGIPPELVKVVTASIIFFVGSHYLIER
YIIRPKKLVKGGK
>M6_Spy1104 CAAX amino terminal protease family
MKGFINYLKIAVLIILAMVFNVLPMILLQKQHDIPMVLNWGIGIFYLVIV
GSVLIVLWRLYQAKQDTPIKQQKMRLVDWGYLALFWLIIRVIAIVGTLVN
QLWSGQQMSANDAAIHTLARLIKGGFPLYTALFVLVIAFIAPIMEELVFR
GFPMIDLFKGKSLKVAGLVTSLVFALPHATNSVEFIMYSCMGIFLFVAYQ
RRGNLKDAILLHIFNNLIEVILLMSIGLGVI
>M6_Spy1613 Predicted kinase related to hydroxyacetone kinase
MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNMSMTMDN
GAKEVADKPASTVGEVGQMLSKGLLMGARGNSGVITSQLFRGFGQSIKGK
DELTGKDLAQAFQVGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTD
DAVEVMQAALDGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSA
LNGDYVTSADFKATPANMSEMINAEHHKSVVGHVATEDITYGYCTEIMVA
LKQGPTYVKEFNYDEFQGYLSGLGDSLLVVNDDEIVKVHVHTEDPGLVMQ
EGLKYGSLIKIKVDNMRNQHEAQVQKTDVEKNKAEVKDFGLIAVVAGEGL
SEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILPNNKNIFMA
AQSAAEVVDIPAAVVATRTVPQGFTSLLAFDPSKSLEDNVADMSTSLSDV
VSGSVTLAVRDTTIDGLEIHENDFLGMVDGKIIVSNPDMEVTLKAAFAKM
IDEDSEIVTIFVGEEGDQDLAEELAGYLGETYEDVEVEIHQGDQPVYPYL
MSVE
>M6_Spy1136 unknown phage protein
MKIAPLNQRVLFKKRVITQDDIGNETSQFTNLFSRWASVNQANSDEIFEV
GQTKRKLQLIVTLRYDSEVASLDTTNTQLIFQGKSFNILSIDHVFFEKKM
VKCRVEEEP
>M6_Spy1112 Putative competence protein/transcription factor
MTKILTALDGKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTIRRPHFA
HVQLAHCQFQAENESEEHLTLKAKLYTSLVRTEAVCIEKYLPELQQIADL
WVNDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTA
LQKQFLYFSSSLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLD
HNIMEMFRLPYQQEILYSYQKKMTVNLSKRIQRALLARHPKWLRRQEKAY
LSGYNLLMLTTDAFYPQWRPVQSSSGFCQIKGNLRPYYESFKVYYKKEKD
KKVQTLFSPKYYVKMDSNRK
>M6_Spy0559 ATP-binding protein
MSDKHINLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALVPKFLELIE
QTNENRRVALVVDMRSRLFFKEINSTLDSIESNPSIDFRILFLDATDGEL
VSRYKETRRSHPLAADGRVLDGIRLERELLSPLKSMSQHVVDTTKLTPRQ
LRKTISDQFSEGSNQASLRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQ
VELREKTGLDEDVFNYVMSHPESEVFYKHLLNLIVPILPAYQKEGKSVLT
VAIGCTGGQHRSVAFAHCLAESLATDWSVNESHRDQNRRKETVNRS
>M6_Spy0751 Metal-dependent hydrolase
MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQRQILETT
IKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKT
YVLTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFVVYAERLAHTIFCM
GYRVVQKDLEGTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKD
YISAPKKGKIITIIGDTRKTSASVKLAKDADVLVHESTYGKGDERIARNH
GHSTNMQAAQIAHEAGAKRLLLNHVSARFLGRDCRQMEKDAATIFENVKM
VQDLEEVII
>M6_Spy1790 Mvi
MSMLNIGIVGLGAISQKAYLPYMRQLSDITWHLSTRNAAVRQQVGQLFGH
AILYSDVKELSKASLDGVFIHAATSAHAELASLFLNQGIPVFMDKPIADN
YLMTKNLYDLAKENQTFLMAGFNRRFTPRVKKLSSLSTKRKVAVEKNDLN
RPGDMTFKLFDFFIHPLDTALFLSEGTLLKGHFQYHLEAGLLSQVMVTLM
TESMTTTASMNLQSGSRREVMEVQRAEETYHLENLDELSIYKGTEKRVLG
FASWDTTLHKRGFETMIDAFLEAISTGVNPVSPESSLLSHWICQQIADSQ
LSYGELTVELPKD
>M6_Spy1523 Immunogenic secreted protein
MNKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSDSSSKEE
NNKNAAPTTSDKTDQGPLDASAETNSNSLVNADDKKRSDSSQSAVGSSDN
KAEAENQVDDKSTDHSKPTDQPKPTDQPKPSPSKVDTAPASSLSRQLPEV
RTPIQSLSPYVSDLDLSEIDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYG
IKADQIDSYLKSTGIAYDSTRINGEKLLQWEKKSGLDVRAIVAIAISESS
LGTQGIATLLGANMFGYAAFDLDPTQASKFNDDSAIVKMTQDTIIKNKNS
NFALQDLKAAKFSRGQLNFASDGGVYFTDTTGSGKRRAQIMEDLDKWIDD
HGGTPVIPAELKVQSSASFASVPAGYKLSKSYDVLGYQASSYAWGQCTWY
VYNRAKELGYQFDPFMGNGGDWKYKAGYALSKTPKVGYAISFAPGQAGAD
GTYGHVSIVEDVRKDGSILISESNCIGLGKISYRTFTAQQAEQLTYVIGK
SKN
>M6_Spy0361 corrin/porphyrin methyltransferase
MQVQKSFKDKKTSGTLYLVPTPIGNLQDMTFRAVATLKEVDFICAEDTRN
TGLLLKHFDIATKQISFHEHNSYEKIPDLIDLLISGRSLAQVSDAGMPSI
SDPGHDLVKAAIDSDIAVVALPGASAGITALIASGLAPQPHVFYGFLPRK
AGQQKAFFEDKHHYTETQMFCESPYRIKDTLTNMLACYGDRQVVLVRELT
KLFEEYQRGSISEILSYLEETPLKGECLLIVAGAQVDSEIELTADVDLVS
LVQKEIQAGAKPNQAIKTIAKAYQVNRQELYQQFHDL
>M6_Spy1484 3-oxoacyl-[acyl-carrier protein] reductase
MEIKGKNIFITGSTRGIGLAMAHQFASLGANIVLNGRSAISEELVASFTD
YGVTVVTISGDVSEASEAKRMVNEAIESLGSIDVLVNNAGITNDKLMLKM
TEEDFERVLKINLTGAFNMTQSVLKPMIKARQGAIINVSSVVGLTGNIGQ
ANYAASKAGMIGFTKSVAREVAARNICVNAIAPGFIESDMTGVLPEKMQE
QILSQIPMKRIGKAQEVAHLASFLVEQDYITGQVIAIDGGMTMQ
>M6_Spy0692 ABC transporter ATP-binding protein
MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTTLLDVLS
GRLGFDGDHSPFSKANDYKIAYLTQDPEFNDAASVLDTVLSSDVKAIQLI
RQYELLMANYTEDKQETLESLMSEMDRLDAWSIESDVKTVLSKLGITDLE
QKVGDLSGGMRRRVQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKT
AKKTVLFITHDRYFLDHVATRIFELDKAGLTEYQGNYQDYVRLKAEQDER
DAANLHKKKQLYKQELAWMRTQPQARATKQQARINRFTDLKKEVHQDSSA
DKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKDFNLIIQNKDRIGIVGD
NGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMDETKRVINY
LQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLK
LLIEKPNVLLLDEPTNDLDIATLTVLENFLANFAGPVITVSHDRYFLDKV
ATKILAFEEGDIRVFYGNYSDYLDEKAFEKETVEADLAKAIVTEEVPLPP
KEEKKRMSYLEKQEWAQIEDKIATIEANIEEIENQMLTVVSDYGQLAQLQ
KELDQRNNDLLLAYERFEYLSGLDI
>M6_Spy0294 Methyltransferase
MLQRDLVNTTGFLRMIMEHNYEKFASVYDAVMDDSLYDLWTDFSLRHLPK
SKGRNRLLELACGTGIQSVRFAQAGFDVTGLDLSQDMLAIAKKRAQSAKK
KIDFIQGNMLDLSQVGQFDFVTCYSDSICYMQDEVDVGDVFKEVYDVLAN
DGIFIFDVHSTYQTDECFPGYSYHENADDFAMVWDTYADEAPHSVVHELT
FFIQEDDGRFSRFDEVHEERTYELLTYDILLEQAGFKSFKVYADFEDKEP
TKTSKRWFFVAYK
>M6_Spy0455 Daunorubicin resistance ATP-binding protein
MVMIEVSHLQKNFSKTIKEPGLKGALKSFVHPQREIFEAVKDLSFEVPKG
QILGFIGANGAGKSTTIKMLTGILKPTSGYCRINGKIPQDNRQNYVRDIG
AVFGQRTQLWWDLALQETYVVLKEIYDVPEKAFRKRMDFLNEVLDLNEFI
KDPVRTLSLGQRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAIT
QINQEEETTILLTTHDLSDIEQLCDRIIMIDKGQEIFDGTVTQLKQSFGK
MKSLSFELKPGQEQVVSQFMGLPDITVERHELSLDIQYDSSRYQTAEIIQ
KTMADFAVRDLKMTDVDIEDIVRRFYRKEL
>M6_Spy0837 Hypothetical membrane spanning protein
MIIKGVTMKFEKKQVFYLVLTFILCYGILANWRNGTAIVTTIYKTSLPFF
YGAAGAYIVNIVMSAYEKVYVYIFKDWSHVLKVKRGICLLLAYLTFFILI
TWIISIVIPDLITSISTLTKFDTITIQEVVNNLEHNKLLARTIQYIGGDG
KLTETIANYSQQLLKQFLTVLTNILTSVTVIASAIINLFISFVFSLYVLA
SKEDLCRQGNTLVDTYTGKYAKRIHYLLELLHQRFHGFFVSQTLEAMILG
SLTASGMFILRLPFAGTIGVLVAFTALIPVIGASIGAAIGFILIMTQSMS
QAIIFIIFLIILQQIEGNFIYPKVVGGSIGLPAMWVLMAITIGASLKGIV
GMITAVPLAATLYQVIKDNIQKRQAIQKKQVS
>M6_Spy0319 Acetyltransferase (GNAT) family
MLIRQVQGSDLEVIATIESDNFSPQEATTRAVLEERIRLIPDTFLVALID
QEIVGYIEGPVVTTPILEDSLFHGVTKNPKTGGYIAITSLSIAKHFQQQG
VGTALLAALKDLVVAQQRTGLILTCHDYLISYYEMNGFINQGISESQHGG
TLWYQMIWKL
>M6_Spy1596 NAD(FAD)-utilizing dehydrogenases
MTQYDTIIIGGGPAGMMAAISSSYYGYKTLLIEKNRRLGKKLAGTGGGRC
NVTNSGNLDVLMAGIPGNGRFLYSVFSQFDNHDIIAFFEENGVKLKEEDH
GRMFPTTDKSRTIIDALEKKIKALGGQVLTSTEVVSVKKQDDLFYLKSAD
QTFTCQKLIVTTGGKSYPSTGSTGFGHDIARHFKLTVTDLEAAESPLLTD
FPHKVLQGISLDDVTLSYDKHVITHDLLFTHFGLSGPAALRLSSFVKGGE
IAELDFLPHLSTDDLTAYLSDQRDKNIKNALKGLLPERVADFLSEDYPEK
VKQLSPKQEKELLDKLKHLQIPITGKMSLAKSFVTKGGVDLKEINPKTLE
SKKVPGLYFAGEVLDINAHTGGFNITSALCSGWIAGKSS
>M6_Spy0876 Conserved membrane protein
MNQTFKQSLPLSFSEEVANSVTHAIGAFAMLILLPISASYAYQTYDLKAA
IGISIFVISLFLMFLSSTIYHSMAYGSVHKYILRIIDHSMIYIAIAGSYT
PVALSLVSGWLGYIIIVLQWGITLFGILYKIFAKRINEKFSLMLYIVMGW
LVVFILPVIIQKTSLAFGLLMLFGGLSYTIGAVFYAKKRPYFHMIWHLFI
LLASALQFIAITFFML
>M6_Spy0223 Integral membrane protein (Rhomboid family)
MTRLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGAQAIYQVGGMFGLLV
KAMPDQLWRLVTPIFIHIGFGHFFVNGLTLYFVGQIVEDLWGSRRFLLLY
VLSGVMGNAFTFWLTPETVAAGASTSLFGLFAAIVVLSFLGKNQALKDLG
KSYQTLIVVNLLMNLFMPNVSMAGHIGGVVGGALLSIVFPTKMRVITMKK
TKRMLALVSYGIILVGVLVLGFL
>M6_Spy0259 CMP-binding factor
MKINQMKKDQLFEGFYLIKSAEVRKTRAGKDFISLTFQDDTGEISGNLWD
AQPYNVEEFTAGKVVSMKGRREVYNGTPQVNQITLRNVRPGEPNDPKDFK
EKAPVSVTEVRDYLEQMLFKIENATWQRIVRALYRKYDKEFYTYPAAKTN
HHAFESGLAYHTATMVRLADSIGDIYPDLNKSLLFAGIMLHDLAKVIELT
GPDNTEYTVRGNLIGHISLINEEITKVISELQIDDTKEEVIVLRHVILSH
HGQLEYGSPVRPRIMEAEIIHMIDNIDANMMMMTTALSRVSEGEMTNRIF
AMDNRSFYKPNY
>M6_Spy1469 Acetyltransferase
MIQQSLVIEEGVPQDAKAVLSLVTAAAKETDFITGVETILEATPQELSDF
LSRSQTSFIDFCLLARLDEKVVGLLNLSGEVLSQGQVEADVFMLVAKTYR
GYGIGQLLLEIALDWAEENPYIESLKLDVQARNTKAIYLYKKYGFRIESM
RKNDIKSKNGDDLDVYHMRKSVSQ
>M6_Spy0743 Rhodanese-related sulfurtransferases
MSEKIRVLLYYKYVSIENAQEYAAKHLEFCKSIGLKGRILIADEGINGTV
SGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLG
LEDNNFDSDINPLETTGKYLNPKQFKEALLDEDTVVLDTRNDYEYDLGHF
RGAIRPDIRNFRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWMVRE
GFKDVGQLHGGIATYGKDPEVQGELWDGAMYVFDDRISVPINHVNPTVIS
KDYFDGTPCERYVNCANPFCNKQIFASEENETKYVRGCSPECRAHERNRY
VQENGLSRQEWAERLEAIGESLPEFVGA
>M6_Spy1678 Oxidoreductase
MKHILFIVGSLREGSFNHQLAAQAQKALEHQAVVSYLNWKDVPVLNQDIE
ANAPLPVVDARQAVQSADAIWIFTPVYNFSIPGSVKNLLDWLSRALNLSD
PTGPSAIGGKVVTVSSVANGGHDQVFDQFKALLPFIRTSVAGEFTKATVN
PDAWGTGRLEISKEIKANLLSQAEALLAAI
>M6_Spy1426 NADH peroxidase
MAIIGQLLCFFFIGLGKTLSYLKNNCYNNTIMTLTTKTIHVIGASFAGLA
FVDKYKDLNPDSQIILIDKESCPNYIPNGINQLFRGDIQDLSDAMWGRAC
LAAQIESNHRFIQAEVLAIEAPSNTLLLKDSQGRVFEEGYETLVCAMGAS
PQSHYIETSQTNKVLVTKYYEESQASLKLIEASQEVLVIGAGLIGLDLAY
SLSLQGKRVKLIEAAERPDFYQTDAELIAPVMAEMSTHHVTFINNKRVTA
IHEIEGKVVAHTEQGDTFQGDLAILAINFRPNTHLLQGQVACALDKTILV
NENLQTSQANIYAIGDMVSLHFGILGMDYYTPLINQAMKTGQALALHLAG
YPIPPLQTVKVLGSSHFGYYRASVGVTEEEAELYMDTCSYLYQNGDSKNL
FWLKLIARKTDGILIGAQLLSKTNALVIANQLGQALALKVTDADLAFQDF
LFLQGHSDLAYHLHEACLKLFEKRLRHED
>M6_Spy1472 Hydrolase (HAD superfamily)
MTKKLIAIDLDGTLLHHDNTISTYTQKTIKAVQDKGHHVIISTGRPYRMA
LDYYLQLNLKTPIITFNGALTHMPEQKWAYEHNVTLDKGYLLRLLQYQDD
FQMDFIASEYRKNVYITMTNPESIDPQLFGVDEITQDMALEITKITRNPN
ALLMQTRHEDKYALAKNMRAFFKDEIEIDSWGGPLNILEISSKNVNKAYA
LNYLLGIYNMDKKDLIAFGDEHNDTEMLAFAGTGYAMKNASPVLLPYADQ
QLNFSNEEDGVAKKLEELFL
>M6_Spy0436 ATPase
MTTMTIAKGNQPIALQLGMLNRHGLIAGATGTGKTVTLKVLAEQLSLAGV
PVFLADIKGDLSNLTKAGEVTDKLAARLATIGVSDYQPQAFPVRM
>M6_Spy1588 Xaa-Pro dipeptidyl-peptidase
MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKLFFHYPD
SDYPLSHLIAKNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEA
DAFLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDN
DYHFFNGKSLATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPQSQ
KPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQITVEDRDFIPL
ETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFM
TSGDYAQIESFKAVIDWLNGRATAYTSHSKTHQVRADWANGLVCTTGKSY
LGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLD
VLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNY
LKNAHQIKCDVVYTHGLQDWNVKPRQVYEIFNALPSTINKHLFLHQGEHV
YMHNWQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNTCLQNWQERKV
FGTSTIKELDLGQELLLIDNHYGEDEFKAYGKDFRAFKAALFEGKANQAL
VDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKKKRLGDLPIAL
TQSSIDNGQNFSRESLKELLFREDSYRVISKGFMNLQNRNNLSSIETIPN
NKWMTVRLPLQPTIYHLEKGDTLRVILYTTDFEHTVRDNSNYALTIDLSQ
SQLIVPIASN
>M6_Spy1611 Acid phosphatase
MKSKKVVSVISLTLSLFLVTGCAKVDNNKSVNRKPATKQTYNSYSDDQLR
SRENTMSVLWYQRAAETQALYLQGYQLATDRLKEQLNKPTDKPYSIVLDI
DETVLDNSPYQAKNVLEGTGFTPESWDYWVQKKEAKPVAGAKDFLQFADQ
NGVQIYYISDRSTTQVDATMENLQKEGIPVQGRDHLLFLEKGVKSKESRR
QKVKETTNVTMLFGDNLLDFADFSKKSQEDRTALLSDLQEEFGRRFIIFP
NPMYGSWEGAIYKGEKLDVLKQLEERRKSLKSFK
>M6_Spy0437 ATPase
MGPMMLSRLLNLNDTQTGVLNIVFKIADEKGWLLIDLKDLQAILKEVGDH
ASDYSSHYGNIAKQSIGAIQRSLLTLEQEGAHQFFGEPALDVADLMQLDV
ASGYGAINILSATKLFQSPTLYTTFLLWLLSELYELLPEVGDLDKPKMVF
FFDEAHLLFKDAPKVFLEKVEQIVRLIRSKGVGIFFVTQNPLDLPETVLA
QLGNRIQHALRAYTPKEQKAVRVAADTFRQNPDLDVARVITELEVGEALI
SVLNDKGQPSIVERAYIMPPKSSFAVLSEIESQQLVQSSPFASKYSQSID
RESAYEKLAAKVLEDNRLAQEAIATAQREKEAKEAIKAQAATKKANRRSV
GRPHKTVVEKATDAFISTTVRTIGRELVRGLLGSLRKR
>M6_Spy0771 ABC transporter ATP-binding protein
MTKIIELINATVDVDNGFEDAKTILDNVTLTIYEHDFLTILGGNGAGKST
LFNVIAGTLSLTRGQIRILGQDVTHWPAEKRALYLSRVFQDPKMGTAPRM
TVAENLLIARQRGEKRSLASRKITEHLASFEDLVKRTGNGLEKHLETPAG
LLSGGQRQALSLLMATLKKPALLLLDEHTAALDPKTSQSLMQLTDEFVTK
DGLTALMITHHMEDALTYGNRLIVMKDGNIIKDLNQMEKEQLTITDYYQL
FD
>M6_Spy1151 Phage DNA polymerase
MKFTLSHSGQTGIQTTTVYPNMVTITDKAILQNVAQFDHVAGLFVQNTRS
NANFIKSDVLVMDIDNDHTENPDEWLTEEFLKDVFADYNFALVTSRSHMQ
TKAGKAPRPKFHIYFQINEVTDKDIYVAMKEELCNQYKFFDDHAKDAARF
FFGNPNAQVIWHDSWLTIDEDLFQVVSIEDEEDFDADFYTPPSGPIQQGS
RNSTMSVFAAKILKRLGVTQEARDGFDEQAQKCVPPLDKAELDTIWGSAV
RFYNRTIKTSKSYVAPDAFNRETLKPDDYSDVGEAGVLAREYANKLAYTN
ATDYLYYDGTHWRENKQLALGAVVHFTDEQLAEAIALLESADKQLQSSGI
DELTIKAGGKRLENAVETPLQLKYLKAYLAAKEFHKFVMKHRDYKNLMAV
YNTAKPILSVELSELDSDDLLLNTPEATYDLRKGINGQQEHNPEDYITKI
TAVSPSDQGMGLWQETLATFFCNDQELIDYVQEIIGMAAIGKVYQEHMII
AYGGGANGKSTFWNTIARVLGSYSGKLSADALTMSNKRNVSPELAELKGK
RLVIASEMAEGMRLNTAVVKQITSTDEIQAEKKYKDPFHFVPSHTLVLYT
NHLPKVGANDDGTWRRLVVIPFNAKITGRSDIKNFADHLYDNAAPAIMSW
IIEGAEKAIKANFKTNVPTAVSSSVKAYREANDWLGHFLGDCCQVGDQLS
EKSGELYSQYRAYCAKNMEYTRSTTDFYSALEQAGFKRKRTSKGNHILGL
KLVEDGYDFLD
>M6_Spy0413 Hypothetical Metal-Binding Protein
MPNIPNEVGSPSLTINLMYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGK
EEKEMSVTFVTNERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDLA
ADPSLAEMMAEFDAYIGELFISIDKAREQSQEYGHSFEREMGFLAVHGFL
HINGYDHYTLEEEKEMFTLQEEILTAYGLTRQ
>M6_Spy1282 Florfenicol resistance protein
MKPSIYSLTRDELIAWAVERGQKQFRATQIWDWLYKKRVQSFEEMTNISK
DFVSILNDSFCVNPLKQRVVQESADGTVKYLFELPDGMLIETVLMRQHYG
HSVCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMLVQKYFDDRKQ
GERVSHVVVMGIGEPFDNYKNVMCFLRVINDDNGLAIGARHITVSTSGLA
HKIRDFANEGVQVNLAVSLHAPNNDLRSRIMRVNRSFPLEKLFSAIEYYI
EKTNRRVTFEYIMLNEVNDSIKQAQELADLTKTIRKLSYVNLIPYNPVSE
HDQYSRSPKERVLAFYDVLKKNGVNCVVRQEHGTDIDAACGQLRSKTMKK
DREKVTATK
>M6_Spy1617 Alpha/beta hydrolase
MKTIRIAKYLGILFLLITLISVGASFYFFHVAQIREEKSFINNKKRSTNN
PLYPAEQSFDALPYEKRQLTNRGLKQVGWYLPAAQKTKKTAIVVHGFTND
KEDMKPYAMLFHDLGYNVLMPDNEAHGESEGNLIGYGWNDRLNVMAWTDQ
LIKENPESQITLFGLSMGAATVMMASGERLPAQVTSLIEDCGYTSVWDEL
KFQAKAMYNLPAFPLLYEVSALSKIRAGFSYGEASSVKQLAKNKRPTLFI
HGDKDDFVPTKMVYDNYKATKGPKEILIVKGAKHAKSFETNPEQYQKKIA
AFLKKVEK
>M6_Spy0035 virulence-associated protein E
MKQEKLIVKSSPLQELHIATGSSRTAKTWKNITLTWQELVERLEKPTVTQ
ETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADS
PSKDFLDRLDLLADYAYVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPV
ARYLANQLGMSNFDDTTYQSVRLMFWPSHSRDAEFTFKYNDEAFLSVDEV
LDTYPDWHDSSFWPESPTHAVKRQREAKKQGDPLSKKGLIGAFCRNYDIR
QAIATFLPEVYEEGATPDRYTYTEGSTANGLVIYDDVFAYSHHGTDPVGD
TLVNAYDLVRIHKFGEQDSEAKDNTPTNKLPSSKAMNAFVSDLPEIKDYL
MAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIKEVPIYWDG
LEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETIVAIKAQA
FSSEVFTESDLNKIVLANGVYDLRDNSFKTKFDPEVHARSSHPVVYDPEA
TCETFEGFLRETVGAENIDFIFEWFGYNFYREYTIQKMLFIYGSGGTGKS
TLINILREMIGADNYSAVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLA
DGATLKMLTGEDTIHADRKNKEPINFYNYAKLSFAMNELPPMRDFSGGLK
RRMMILEMDKVLTQEVKAKYPLDKIMSEVPGIFNRAMEGLRKALSKRDFS
ISASMRSSVEKWEKGNDVVAMFLEDECDLSEDFKVPVRDVYPAYKFYCQD
SGYKPLARNSFTQRMNELNFENKNAKMGGKTVRCWIGFRIKGEF
>M6_Spy0288 Putative lipase
MLFQKKYDKIESTNYFGDDMSIDDYRPTYMVEAIYDLRANDLLRHGITAV
LVDLDNTLIAWNNPDGTPEVRAWLDEMTIADISVVVVSNNKHSRVERAVS
RFGVDFISRALKPFAYGIEKAIARYGFDRNEVIMVGDQLMTDIRASHRAG
IKSVLVKPLVASDAWNTKINRWREHRVMAKLEEKYGKLSYQKGI
>M6_Spy0484 Macrolide-efflux protein
MNNRKKNIQYLVYSKVIYRIGDVMFDFANNTFLAGLNPASLSLVAVYQSL
ESVIGVLFNLFGGVIADSFKRKKIIITTNILCGTACLVLSFLTKEQWLVY
AIVLTNVILAFMSAFSSPSYKAFTKEIVKKDSISQLNSLLETTSTVIKVT
VPMVAIFLYKLLGIHGVLLLDGLSFLIAALLISFILPVNDEVVIKEKVTI
REIFNDLKIGFKYVYSHKSIFIITVLSALVNFFLAAYNLLLPYSNQMFGE
ISTGLYGTFLTAEAIGGFIGAILSGFVNKELSSMRLILFLSLSGLMLMLA
PPFYIMFHNAIILALSPALFSLFLSIFNIQFFSLVQKDVDNDFLGRVFGI
IFTITILFMPIGTGFFSVALNPNNSFNLFIIGSCITILSLVFRILFKKYN
IR
>M6_Spy0273 ABC transporter ATP-binding protein
MSILEINNLHVSIEGKEILKGVNLTLKTGEVAAIMGPNGTGKSTLSAAIM
GNPNYEVTQGQILLDGVNILDLEVDERARLGLFLAMQYPSEIPGITNAEF
MRAAMNAGKADEDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGE
KKRNEILQLLMLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGKDFGAMI
ITHYQRLLNYITPDLVHVMMDGRIVLSGDAALATRLEKEGYAGIAQDLGI
EYKEES
>M6_Spy0618 Hypothetical cytosolic protein
MSDTPKYTQDQVIAIKNRILEALETVIDPELGIDVVNLGLIYEIRFNDNG
YTEIDMTLTTMGCPLADLLTDYIHDALQDVPEVTKTEVKLVWYPAWTVDK
MSRYARIALGIR
>M6_Spy1466 Bis(5'-nucleosyl)-tetraphosphatase(asymmetrical)
MENCIFCSIIQGDIPSSKVYEDEQVLAFLDISQTTKGHTLVIPKQHVRNL
LEMTAETASHLFARIPKIARAIQSATGATAMNIINNNEALAGQTVFHAHV
HLVPRYNEEDGISIQYTTHEPDFPVLEKLARQINQEVSS
>M6_Spy0332 CBS domain containing protein
MIAKEFETFLMSHLDNYLIPEQDLAIFIDTHNADHVMLLLVSNGFSRVPV
ITREKKYVGTISISDIMMYQSKRQLTDWEMSQTDIGEMVNTKIETISITS
SLTEIMHKLIDFPFLPVVDRANRFVGIITRKSILKAVNSLLHDFTDDYTI
IKK
>M6_Spy0494 Hydrolase (HAD superfamily)
MIKLIATDMDGTFLAEDGTYNQEQLAALLPKLAEKGILFAVSSGRSLLAI
DQLFEPFLDQIAVIAENGSVVQYRGEILFADMMTKEQYTEVAKKVLANPH
YVETGMVFSGQKAAYILKGASEEYIQKTKHYYANVKVINGFEDMENDAIF
KVSTNFTGHTVLEGSDWLNQALPYATAVTTGFDSIDIILKEVNKGFGMEH
LCQALGIKKAETIAFGDNFNDYQMLEFAGRAIATENARPEIKVISDQVIG
HCNDGAVLTYLKGLV
>M6_Spy1574 CvpA family membrane protein
MLSLLIVLVLTWNFYIGYSRGIILQSFYVLGALLSLLVANRFYIGLAHKL
TLWIPYSNPVEGTSVFFFKSVDIFVLDKVYYAGLAFFIIFLLGYALSRFL
GIFVHFLLLDYFDNQWTKCLSGGLALLVSLLFLNMLLSIFATVPMPFLQH
YLHSSFLARLVIEHLPPLTIIIQKLWMQAII
>M6_Spy0910 ABC transporter ATP-binding protein
MTAFLMTVKEETMSILEVKQLSHGFGDRAIFENVSFRLLKGEHIGLVGAN
GEGKSTFMSIVTGHLQPDEGKVEWSKYVTAGYLDQHTVLESGQTVRDVLR
TAFDELFKTENRINEIYASMADDKADIAVLMEEVGELQDRLESRDFYTLD
AKIDEVARALGVMDFGMESDVTSLSGGQRTKVLLAKLLLEKPDILLLDEP
TNHLDAKHIEWLKRYLQHYENAFVLISHDISFLNDVINIVYHVENQSLVR
YTGDYYQFQAVYEMKQSQLEAAYERQQKEIANLQDFVNRNKARVATRNMA
MSRQKKLDKMDIIELQAEKPKPNFEFKQARTPSRFIFQTKNLVIGYDYPL
TKEPLNITFERNQKIAIVGANGIGKSTLLKSLLGVIEPLEGHIVTGDFLE
VGYFEQEVTGVNRQTPLEVVWDAFPALNQAEVRAALARCGLTSKHIESQI
QVLSGGEQAKVRFCLLMNRENNVLILDEPTNHLDIDAKNELKRALKAYKG
SILMVCHEPDFYNGWVTDTWDFSKLT
>M6_Spy0764 Hypothetical membrane spanning protein
MPLIPEKSRTDSLFYKWFLNNQATMALVITLLAFLTIFVFTKISFLFMPV
ISFFAVIMLPLVISTILYYLTKPLVDLINHLGPNRTTSIFIVFGLITLLF
VWAISGFVPMVQTQLTSFIEDLPKYVGKVNEEANKLLENEWLVSYKPQLQ
DMLTHTSQKALDYAQSFSKNAIDWAGNFAGAIARITVAIIISPFILFYFL
RDSSHMKNGLVNVLPLKLRVPMVRVLGDINKQLSGYVQGQVTVAIVVGFM
FSIMFSLVGLKYAITFGIIAGFLNMIPYLGSFLAMIPVVIMAMVQGPFVL
VKVLVIFMIEQTIEGRFVAPLVLGNKLSIHPITIMFLLLTAGSMFGVWGV
FLVIPIYASVKVVIKELFDWYKKVSGLYDEEVLVIEEVKDHVK
>M6_Spy1393 D-beta-hydroxybutyrate dehydrogenase
MTHTKEVAFITGAASGIGKQIGETLLKEGKTVVFSDINQEKLDQVVADYT
KEGYDAFSVVCDVTKEEAINAAIDTVVEKYGRIDILVNNAGLQHVAMIED
FPTEKFEFMIKIMLTAPFIAIKRAFPTMKAQKHGRIINMASINGVIGFAG
KSAYNSAKHGLIGLTKVTALEAADSGITVNAICPGYVDTPLVRGQFEDLS
KTRGIPLENVLEEVPYPLVPQKRLIDVQEIADYVSFLASDKAKGVTGQAC
ILDGGYTAQ
>M6_Spy0610 Neutral zinc metallopeptidase family
MKTDDLRESQQVEDRRGQSSGSFGGGGLGGGLLLQLLFSRGGWKTKLVIL
LLLLVMGGGGLSGVLGGKPSSTNNNAYQSSQVTRTNGDKASQEQVSFVSK
VFASTEDYWTKTFREKGLTYHKPTLVLYTGATQTACGRGQASSGPFYCPG
DQKVYLDISFYNELSTKYGAKGDFAMAYVIAHEVGHHIQNELGIMDNYAS
ARQGKSKAKANQLNVKLELQADYYAGAWANYVQGQGLLEKGDIEEAMAAA
HAVGDDTLQEETYGRTVPDSFTHGTSKQRQRWFDRGYQYGDFEHGDTFSI
PYSKL
>M6_Spy0342 SAM-dependent methyltransferase
MTDLDRRKVMLKRPIHLSHDFLAEVVDKSSVVVDATMGNGNDTAFLAQLA
KKVYAFDVQEQAIRKTSERLAQLGLLNAELILAGHEAVDQYVTEPVRAAI
FNLGYLPSADKSIITLPNTTLQALSKLLTLLMVGGRIAIMVYYGHDGGSL
EKDALLDFVKQLDQRKVSAMLYQPLNQVNTPPFLIMLEKLADV
>M6_Spy1122 ComE operon protein 3
MRTHTDTDHMGDIEVVAKAIRIKEILTSQGSLSQPSFVRRLRRLKCRVRV
LAAGDQLPIMGNVLQVLYPWQLGDGKNNDSLVLYGRLLNQTFLFTGDLEK
EGENEIIKRYPQLKVDYLKAGHHGSNTSSSAAFLDHIQPKVAFISAGKNN
RYQHPHRETLARLEDREISYYRTDIQGAIRLTGWLNWHIETVR
>M6_Spy0326 Hydrolase (HAD superfamily)
MHYTEDKEYMEHVGHLIAHPRFQKLSHIVQHQHSTRLEHSINVSYSSYKL
AKRFGWDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLT
ELNKKEEDIILKHMWGATIAFPRYKESYIVTMVDKYWAVKEAVTPLRQKW
SNRRFLRRKTLQSHNR
>M6_Spy0846 ATP-NAD kinase
MMTQMNYTGKVKRVAIIANGKYQSKRVASKLFSVFKDDPDFYLSKKNPDI
VISIGGDGMLLSAFHMYEKELDKVRFVGIHTGHLGFYTDYRDFEVDKLID
NLRKDKGEQISYPILKVAITLDDGRVVKARALNEATVKRIEKTMVADVII
NHVKFESFRGDGISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNN
RVFRTLGSSIIIPKKDKIELVPKRLGIYTISIDNKTYQLKNVTKVEYFID
DEKIHFVSSPSHTSFWERVKDAFIGEIDS
>M6_Spy0517 Hydrolase (HAD superfamily)
MITAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSVMNQAYIRFRHYSDVG
FPRVMAGEWTTEYFRFWRCKETLLEFGYREIDEAAGVHFQEVYEHELENI
TMLDEMRMTLDFLKSKNVPMGIITNGPTEHQLKKVRKLGLYDYIDPKRVI
VSQATGFQKPEKEIFNLAAEQFDMNPQTTLYVGDSYDNDIMGAFNGGWHS
MWFNHRDRQLKPGTKPVYDVAIDNFEQLFGAVKVLFDLPDNKFIFDINDK
KNPILQMGINNGLMMAAERLLESNMSIDKVVILLRLTKQQEKVLRLKYAR
>M6_Spy1867 Zinc protease
MKIVQGVQLHLIKTKQFKTNHITFRFSGDLNQKTVAKRVLVAQMLATANE
CYPTVRQFREKLARLYGASLSTNVLTKGLVHIVDIDITFIQDRYACNGEK
ILDEMIQFLKDILFSPLLSIAQYQPKVFETEKNNLINYIESDREDSFYYS
SLKVKELFYCNKNLQMSEYGSPELIAKETAYTSYQEFHKMLNEDQIDIFI
LGDFDDYRVVQLIHQFPLDNRNKNLNFFHLQNSVNIIKESIEKRAVHQSI
LQLAYHFPSVFGQRDYYALVLLNGLLGSFSHSRLFIKIREEEGLAYSIGC
RFDSYTGLFEIYTGIDSQHRTKTLQLIIQELNDIKMGRFSEQLIKKTRLM
LLNNALLSEDYNKNIIERIYTSSYIDSSYSIKNWIKGVNEVNKADIIKVA
NLLKLQTVYFLEGI
>M6_Spy0772 Zn-dependent hydrolase
MTDIKMIALGGVREYGKNFYLVEINDSMFILDAGLKYPENEQLGVDLVIP
NLDYVIENKGKVQGIFLSHGHADAIGALPYLLAEVSAPVFGSELTIELAK
LFVKSNNSTKKFNNFHVVDSDTEIEFKDGLVSFFRTTHSIPESMGIVIGT
DKGNIVYTGDFKFDQAAREGYQTDLLRLAEIGKEGVLALLSDSVNATSND
QIASESEVGEEMDSVISDADGRVIVAAVASNLVRIQQVFDSATAHGRRVV
LTGTDAENIVRTALRLEKLMITDERLLIKPKDMSKFEDHELIILEAGRMG
EPINSLQKMAAGRHRYVQIKEGDLVYIVTTPSTAKEAMVARVENLIYKAG
GSVKLITQNLRVSGHANGRDLQLLMNLLKPQYLFPVQGEYRDLAAHAKLA
EEVGIFPENIHILKRGDIMVLNDEGFLHEGGVPASDVMIDGNAIGDVGNI
VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSHDILRE
SAELVNTTVGNYLKKDTFDWGELKGNVRDDLSKFLFEQTKRRPAILPVVM
EVR
>M6_Spy0240 Jag
MVLFTGKTVEEAIETGLQELGLSRLKAHIKVISKEKKGFLGFGKKPAQVD
IEGISDKTVYKADKKATRGVPEDINQKHAPAVNSADVEPEEIKATQKLEA
EDTKVVPLMPEDSPAQTPSNLAETVTETKAQQPSIPVEESEVPQDAGNDG
FSKDIEKAAQEVSDYVTKIIYEMDIEATVETSNNRRQINLQIETPEAGRV
IGYHGKVLKSLQLLAQNFLHDRYSKNFSVSLNVHDYVEHRTETLIDFTQK
VAKRVLESGQDYTMDPMSNSERKIVHKTVSSIEGVDSYSEGNDPNRYVVV
SLQR
>M6_Spy1813 unknown phage protein
MTTEEYFKKLLEDSEKQPTNWLSDRVLDKNIKMLDEDIEAEWDDFPLFTK
KIFINTTQRDYNKADAVVKFLESIPIEMEYKKGLNIVIQALNELKDSLKN
QVLGVIDNQILFPNDKEDTK
>M6_Spy1199 Holin
MIIDLTSLIHLFGDLVRTVEIHVFTLFVCFDIITGLTKGITNKRANSTKG
LSGIIKHFLVVLLVYTVYPYLILLGAKPLAVAFVLFFIACYGISIVENWG
QLGLPMPSFVRSFFEKLKRDTDQFDIATIKIDKTGVKLEAPQVDLKQKEE
E
>M6_Spy0090 Alcohol dehydrogenase
MKAVVVNQASTGVEVVEHDLPNVGHGEALVKVEYCGVCHTDLHVAHGDFG
QVPGRILGHEGIGIVEEIGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGR
ETLCRSVKNAGYSVDGGMSEYAVVTADYAVKVPEGLDPAQASSITCAGVT
TYKAIKEAGAAPGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKL
ELAKEVGADILVNGKEIEDVPGYIQEKIGGAHGVVVTAVSKVAFNQAIDS
VRAGGTVVAVGLPSEYMELSIVKTVLDGIKVVGSLVGTRKDLEEAFAFGA
EGLVAPVVEKVPVDTAPEVFDEMERGLIQGRKVLDFIS
>M6_Spy0930 Nucleoside transport ATP-binding protein
MKGNDPMTQHVIEMREITKKFGDFVANDHINLNVRKGEIRALLGENGAGK
STLMNMLAGLLEPTSGEIVINDKPVQIDSPSKSAKLGIGMVHQHFMLVEA
FTVAENIILGNEVVKNGCLDLNQASKDIKVLSEKYGLAINPSAKVSDISV
GAQQRVEILKTLYRGADILIFDEPTAVLTPAEIKELMTIMKNLVKEGKSI
ILITHKLDEIRAVADRVTVIRRGKSIETVDVAGATSQDLAEMMVGRSVSF
TTSKKAAEPKDVVLSIKNLEVDENRGIPAVKGLSLDVRAGEIVGIAGIDG
NGQSELIQAITGLRKVKSGSIMIKNNEVTHLSSRKITELSVGHVPEDRHR
DGLILDLSLAENTALQTYYKQPLSQNGILNYTKINDYARQLMKEFDVRGA
NELVPARGFSGGNQQKAIIAREVDRDPDLLIVSQPTRGLDVGAIEYIHKR
LIKERDKGKAVLVVSFELDEILNLSDRIAVIHDGKIQGIVLPENTNKQEL
GILMAGGSIHKEEGHV
>M6_Spy0471 Zn-dependent hydrolase (beta-lactamase superfamily)
MNESGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLLAEIDRK
PEDLDAILITHEHSDHIKGVGVMARKYHLDIYANEKTWQLMDECNMLGKL
DASQKHIFQRDKVLTFGDVDIESFGVSHDAVDPQFYRIMKDNKSFVMLTD
TGYVSDRMTGIIENADGYLIESNHDIEILRSGSYPWSLKQRILSDLGHLS
NEDGAGAMIRSLGYNTKKIYLGHLSKENNIKELAHMTMVNQLAMADLAVG
TDFTVHDTSPDTACPLTDI
>M6_Spy1057 CgtA
MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGGSVIFRV
DEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGAEDLIVFVPQGTTVRDA
ETGKVITDLVEHGQEVVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEE
RQLELELKILADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLG
MVRTKSGDSFAMADLPGLIEGASQGVGLGTQFLRHIERTRVILHVIDMSA
SEGRDPYEDYVSINNELETYNLRLMERPQIIVANKMDMPEAQENLKAFKK
KLAAQYDEFDDLPMIFPISSLAHQGLENLLEATAELLAKTDEFLLYDEAD
LVDEEAYYGFAETEKDFEITRDDDATWVLSGEKLERLFVMTNMERDESIM
KFARQLRGMGVDEALRERGAKDGDLVRIGKFEFEFVD
>M6_Spy0545 Gluconate 5-dehydrogenase
MENMFSLQGKIALITGASYGIGFEIAKAYAQAGATIVFNDIKQELVDKGL
TAYRELGIEAHGYVCDVTDEAGIQQMVSQIEDEVGVIDILVNNAGIIRRT
PMLEMAAEDFRQVIDIDLNAPFIVSKAVLPSMIAKGHGKIINICSMMSEL
GRETVSAYAAAKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLR
ERQADGSRHPFDQFIIAKTPAARWGATEDLAGPAVFLASDASNFVNGHIL
YVDGGILAYIGKQP
>M6_Spy0438 Multidrug resistance protein B
MNWRQNLKVAWLGNFFTGASFSLVMPFMALYVENLGTPTELVEYYAGLAV
AVTALASALFAPVWGKLADRYGRKPMMLRASFVMTFTMGGLAIIPNVFWL
LILRLLTGVFAGYVPNATALIASQAPKEESGYALGTLATGVTAGALIGPL
LGGILAELLGIRQVFLLVGVILFLCSLMTAVYVKEEFKPIRRFEMIPTKV
ILKQVKSPQIMLGLFVTSMIIQISAQSVAPILSLYIRHLGQTHNLMFTSG
LVVSAMGFSSLFSSSYLGKLGDRFGNHRLLLAALCYSFIMYFSSALAQTS
FQLGVLRFAYGFGVGALMPSINSLLTKLTPKEGISRVFAYNQMFSNLGQV
IGPFIGSNVAVVLGYRSVFYVTSLIVFVNLIWSLIIFRKYIKVKDIV
>M6_Spy1127 Phage structural protein
MADYGSNNDRGYNLLLRVEETGTSTANNTSTVRVQLWLRNGQTTFGMYNC
SASVSIDGQTLSWSGRPDMYSMNSSLHLIDKTITIAHNSNGQKTIGFSAT
FSGSGGWSPGTLNTGYQSLRLRDIPRSSTASVSGNMMGSPITISITRASG
DFTHKVTWQFGSLSGVVATGATTSCSWTPEVAKLAPQIPNATSGIGTILV
QTIYGGKVIGESRIQVTLQLPSSVVPSLSSISLSDLNTIAQNAITGNTFV
SLESNPKVTFNGATGIYGSTIPASGYRAEVFKFEGNSWIQLQNVATAQNG
GVGGINHVGRAKISAFVTDSRGRQSPRKEVEISLLEYFKPILSFTSVRVG
TTMNQLNVIRKVKIAPLIVGNSQKNRATMTWDILDLSTGTKTTNVGGAAN
WSTTTEHTKENFQATLNGTYDQTKSYTIIGHLRDLFYETDFEFTVGPEKV
VYGLSPTGMGIGKAWTRGVLDVDGSQPSYFDGDIIMRNKKLIDIFYPIGT
IYESTSSESPSTFMGGKWERFGNGRVLVGVSETESEFNTVSKTGGSKTHT
LTINEMPVHSHPQYVSANSGNQATRRDYSSDGSSSLYPQGNNTGNLEEDR
LITIYNLILQFIGGDVPLRGETMKQEVLTNKLVFSGIGGVIGSIFGEIDG
FLYGLLIFMLIDYVTGIMAAIVEKNLSSSIGKKGIFKKAMIICLVAVAHM
IDLHVLKQGGAVRTAVIFFYFSNEGLSILENATRIGLPVPNRIKQVLRQL
NEDKEDENDK
>M6_Spy1262 MutT
MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWFLPGGEI
EAGEGQLQALERELIEELGFSATIGSYYGQADEYFYSRHRDTHFYHPAYL
YEVTAFQAVSKPLEDFNNLGWFSPIEAIAKLKRESHQWGVKEWQKKHHST
N
>M6_Spy0289 GTP-binding protein
MEELFCIGCGIQIQTEDKEKAGFTPAAALKKGMETGELYCQRCFRLRHYN
EITDVHITDDEFLRLLHEVGDSDALVVNVIDIFDFNGSIIPGLSRFISGN
DVLLVGNKKDILPKSVKDGKVTQWLAERAHEEGLRPLDVMLTSAQNKYAI
KDLIERINELRNGRDVYVVGVTNVGKSTLINAIIQEITGNKDVITTSRFP
GTTLDKIEIPLDDGTFIFDTPGIIHRHQMAHYLSPKELKIVSPKKEIKPK
TYQLNPEQTLFLGGLSRFDFINGERQGFTAFFDNQLELHRTKLAGANAFY
DKHVGTLLTPPGKKELTAFPKLVRHEFTIDQKMDIVFSGLGWIRVNGQKD
SKAIVAAWAPEGVAVIVRKAII
>M6_Spy0495 Hydrolase (HAD superfamily)
MNIRILALDLDGTLYNTEKIVTDANKKALAAAREKGVKVVITTGRPLKAI
GNLLEELDLLDHDDYSITFNGGLVQRNTGEVLDKSSLSFDQICQIQQALE
AVGLPTDIISGGDVYSIPSKDGRHSQYHLANPLLTFIEVTSVAELPKDIT
YNKIVTVTDPDFLDQQIIKLSPSLFEDFEAFKSRDIIFEIMPKGIDKAFG
LNLLCQHLGLEARHVMAMGDEANDFAMLEWAGLGVAMANGVSGAKAVADA
VTTLTNDESGVAEAVKTFILEEES
>M6_Spy0709 YihA
MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSSFINTIL
GRKNLARTSSKPGKTQLLNFFNIDNKLRFVDVPGYGYAKVSKSERAKWGK
MIEEYLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKA
DKIPRGKWNKHESVVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV
>M6_Spy0833 Zn-dependent alcohol dehydrogenases and related dehydrogenases
MNWLITSQPYKELNMKAATYLSTGNLQLIDKPKPVIIKPTDAIVQVVKTT
ICGTDLHILGGDVPACKEGTILGHEGIGIVKEVGDAVTNFKIGDKVIISC
VTSCHTCYYCKRGLSSHCEDGGWILGHLINGTQAEYVHIPHADGSLYHAP
DTIDDEALVMLSDILPTSYEIGVLPSHVKPGDNVCIVGAGPVGLAALLTV
QFFSPANIIMVDLSQNRLEAAKTFGATHTICSGSSEEVKAIIDDITNGRG
VDISMECVGYPATFDICQKIISVGGHIANVGVHGKPVDFNLDELWIKNIT
LNTPIQLKCY
>M6_Spy1802 Multidrug resistance protein B
MQEFLNLPKQIQLRQLVRFVTITLGSSIFPFMAMYYTTYFGTFWTGLLMM
ITSLMGFVGTLYGGHLSDALGRKKVIMIGSVGTTLGWFLTILANLPNAAI
PWLTFAGILLVEIASSFYSPAYEAMLIDLTDESNRRFVYTINYWFINIAV
MFGAGLSGLFYDHHFLALLVALLLVNVLCFGVAYYYFDETRPETHAFDHG
KGLLASFQNYRQVFHDRAFVLFTLGAIFSGSIWMQMDNYVPVHLKLYFQP
TAVLGFQVTSSKMLSLMVLTNTMLIVLFMTVVNKLTEKWKLLPQLVVGSL
LFTLGMLLAFTFTQFYAIWLSVVLLTFGEMINVPASQVLRADMMDHSQIG
SYTGFVSMAQPLGAILASLLVSVSHFTGPLGVQCLFVVIALLGIYFTVVS
AKMKKV
>M6_Spy0212 BioY
MFTTKELVKVAMMTTLIIILGFIPAIPLGFIPVPIVLQNLGVMLAGLMLG
GKKGTLSVFLFLVIGLFLPVFSGSRTTIPVLMGPSAGYVIAYLLVPIVFS
LLYRNWFSKSTPLAFLALFISGVLLVDVMGAIWLAAYTGMPLMTSLLSNL
VFIPGDTIKAIIATIIAVKYKDSFLNTKQ
>M6_Spy1817 Virulence-associated protein E
MLKQNTEKEGRTIEQEDLKNLENEITEARENEDKYFSTFKGVRGQLIKEC
QEMKDEAFKIAYDGVMADSKHLENVKAGRLTEVQHEELAKEKGQEASEKA
LPKTPLGVAIMLKHYLRFIRVKPEAQGQKAPLYFFHPDHGVWLEDNEFLQ
DLISVIFPNATEKQAFDTLYKIARQSQLKEIQREYTVIGNQLYNYKTGQF
EELTPDITVTRKIKTGYNKKAKEPTIKGWKPTAWLLELFDGDAELYNLAI
QIIKASITGQSLQKIFWLFGEGGTGKGTFQQLLINLVGMDNVASLKITEL
AKSRFTTSILLGKSIVIGDDIQKDAVIKDTSDIFSLATGDIMTIEDKGKR
PYSIRLNMTVVQSSNGLPRMNGDKSAIDRRFRILPFTKVFKGKPNKAIRN
DYINRKEVLEYLLKLAIETPITDINPKASIEILEEHHKEMNPVIDFVSKF
FTDELTSEFIPNSFVYHVWKGFLEYYDIKQIKSERGLHKEIKSNLPEGFE
AGQKVIPVGRQLHTGFYPKEDLPLFASASYANGRASPEKRKKPKNERGYY
NHWPTHKKQKKT
>M6_Spy0878 GTP-binding protein
MAMIQWFPGHMSKARRQVQENVKHVDFVTILVDARLPLSSQNPMLTKIVG
DKPKLMILNKADLADATRTKEWKAYYESQGIKTLAINSKEQSTVKKVTEA
AKELMADKIQRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIAVVG
NKPGVTKGQQWLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQL
LPMDEVTIFGLNYFKTHYPSRLTKRFKNIPLEEEAPEIIMTLTRQLGFKD
DYDRFYTLFVKEVRDGKLGQYTLDQVGDMDVD
>M6_Spy0677 Hypothetical membrane spanning protein
MTTTDKETFSSFMNKILAGTAIAIVVALIPNAILATFLKPLLPNMAATEF
LHIVQVFQFFTPIMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVI
QKGVATGTFQLRGIGDLINMMITASLAVLAVKYFGNRFGSLTIILLPITI
GTGVGYIGWKFLPYVSYVTTLIGQGINSFTTLQPILMSILIAVAFSLIIV
SPISTVAIGLAIGLNGMAAGAASMGIASTAAVLVWATLKVNKSGVPIAIA
LGAMKMMMPNFLKHPIMAIPMVFTAAISSLTVPLFNLVGTPASSGFGLVG
AVGPIASLAGGSSILIIILAWIIVPFAVAFAAHKVSKDILKLYKEDIFVF
EG
>M6_Spy0875 Hypothetical protein
MKTVRIFYNPNSGKKEDQLAGQVKDYFCQHGFSEDSVEIITPKDADQAFQ
LAKQAAKDKIDLVIPLGGDGTLNKIIGGIYEGGAHCLIGLVPSGTVNNFA
KAMHIPLQITEALDTILTGQIKQVDICKANQQYMISSLTLGLLADIAADV
TAEEKRRFGPLAFLKDSIRILKRNRSYAISLISHNHRIHLKTKFLLITMT
NTIAGFPSFSPGAQADDGYFQVYTMKKVSFFKFLWHINDFKQGDFSKAEE
ISHFQANTLSLLPQAKKQAILPRARIDGDKSDYLPIQLDIIPKAISIIVP
TED
>M6_Spy0768 ABC transporter substrate-binding protein
MKNKSLIATLLVLTVIVIGSLLSKGVSKENRDLANQQNITIGILQLVTHE
ALDDIKRGIEDQLKKQKPQKQNVVIKVMNAEGDQSKIQTMSRQLVQSGSD
IVIGIATPAAQGLAAASKDIPVVMSAVSDPVGSRLVMQLDQPEANVTGLS
NKVPVKQTIDLMKKLTPHVKTVGILYASNEDNSLSQVKEFRRLARKKGYQ
VISYAVPSTNEVPATMSVMLGKVDAVFIPQDNTIASAFSSVMTTSKAAKI
PVYTSVDRMVEKGGLAAISQNQYDLGVQTANQVLKLIKGKRVVDVPVKVV
DIGQPLINKNVAAELGIAINREDFPSASFIEN
>M6_Spy0315 GTP-binding protein
MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLN
RQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDAD
EYVSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGI
GTGDVLDAIVENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRV
IASPVAGTTRDAIDTHFTDADGQEFTMIDTAGMRKSGKIYENTEKYSVMR
AMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTID
KDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQRLNKLPDLIKRISESQ
NKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKPPTFVVFVN
EEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK
>M6_Spy1176 Methyltransferase
MKVDFSKVKITLQTFTSSLFYVKITGMIKAILKEGERIDQLFSSDVGIIQ
NKDVFSYSIDSVLLSRFPKMPSKGLIVDLCSGNGAVGLFASTRTKAAIVE
VELQKRLADMGQRSIQLNQLEDQVTMICDDLKNLLNHVPRSGVDLMLCNP
PYFKSHESSKKNVSEHYLLARHEVTTNLEEICQVARHALKSNGRLAMVHR
PDRFLEIIDSLRANGLAPKRVQFVYPKLGKSANMLLIEAIKDGSIEGMTI
LPPLVVHKENGEYTDHIFEIYFGTASKGKPNHDH
>M6_Spy0213 Metal-dependent hydrolase
MKLTTLGSWGAYPYQDAGTTSYLVTGHDGFQLLMDAGSRALNELEKEISP
LDLDAVIISHYHPDHVADLGVLRHYFQLYPKHLWQPKVLPIYGHDEDRHE
FAKLSIPDVSEGRAYDVTGVEQIGPFDITFLKTVHPVVCYAFRIVERATG
QVLVFTGDSGYFEGLADFAKEADLFLADVYLYEGNENHMAHLTSKEAGLM
ASQAGVKKLVLTHMPPVPPEGIDPDNHLEVLRQETQAYAGNIPVDLALPH
KSWNLGSLS
>M6_Spy1442 Hydrolase (HAD superfamily)
MATVKNGTSLKSNGKRKDRMIQLIAIDLDGTLLNQDKQIPKENITAIQEA
AQSGLKIVLCTGRPQSGTRPYFDQLGLTQEEFLIINNGCSTYSSPDWQLR
HSKMLKVSDIELLEELSQSFPDIYLTLTEENDYLVLEEEVPDLVQEDGDL
VFTIVKPVSLAELSDTPRLIFQAMYLGEKAALDAFERAVRNQLSQSFHVV
RSQDNILEILPQGVSKASALKELVEDLGLTADQVMAIGDAPNDIEMLTYA
GLGVAMENASAAIKPLADKVTLTNDMAGVAQAIRQFALAAQKD
>M6_Spy0567 Phosphoesterase, DHH family protein
MITTFETILDKIKAHQTIIIHRHQNPDPDALGSQAGLKEIIAQNFPDKKV
LMTGFDEPSLAWISQMDQVTDKDYKEALVIITDTANRPRIDDERYTLGQC
LIKIDHHPNDDVYGDFYYVDTSASSASEIIADFAFSQNLTLSDKAAKLLY
TGIVGDTGRFLYASTTSKTLSIASQLRHFEFDFAAISRQMDSFPLKIAKL
QSYVFEHLTIDESGAAYVLVSQETLKHFDVTLAESSAIVCAPGKIDNVQA
WAIFVELTDGNYRVRMRSKEKIINGIAKRHGGGGHPLASGANSASLEENQ
AIFRELIAVCQEI
>M6_Spy1165 Macrolide-specific ABC-type efflux carrier
MELILKAKDISVEFKGHDVLDINELEVYDYDRIGLVGANGAGKSTLFKVL
LGELIPPGCKMNHLGELAYIPQLDEVTLQEEKDFALVGKLGVEQLNIQTM
SGGEETRLKIAQALSAQVHGILADEPTSHLDREGIDFLIGQLKYFTGALL
VISHDRYFLDEIVDKIWELKDGKITEYWGNYSDYLRQKEEERKRQAAEYE
QFIAERARLERAAEEKRKQARKIEQKAKGSSKKKSTEGGGRLAHQKSIGS
KEKKMHNAAKSLENRIAALGKVEAPEGIRRIRFRQSKALELHNPYPIVGA
EINKVFGDKALFENASFQIPLGAKVALTGGNGTGKTTLIQMILNHEEGIS
ISPKAKIGYFAQNGYKYNSNQNVMEFMQKDCDYNISEIRSVLASMGFKQN
DIGKSLSVLSGGEIIKLLLAKMLMGRYNILIMDEPSNFLDIPSLEALEIL
MKEYTGTIVFITHDKRLLENVADVVYEIRDKKIKLKH
>M6_Spy0206 CoA binding protein
MIYSFQNPSEDVLKAYLESAKTIAVVGLSDRKDTAAYGVAKFMQAMDYRI
IPVNPKLAGQLILGEKVYASIKAIPFEVDIVDVFRRSEFLPEVARDFLAG
QAKVFWAQLGLENQEAQTILRSAGKEAIVMNRCLKIDYLQLVAKPECITN
H
>M6_Spy0919 ATPase associated with chromosome architecture/replication
MPSSFDLLGEMIGLLQTEQLTSSLACPLPNALTKRQDLWRALINQRPALP
LSKDYLNLEDAYLDDWRASFVPVSVKDCQKTNYTSLFLYHGDIRYLAVDA
IVNAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIG
QAKLTSAYHLPASYIIHTVGPRITKGRHVSPIRADLLARCYRSSLDLAVK
AGLTSLAFCSISTGEFGFPKKEAAQIAIKTVLKWQAEHPESKTLTVIFNT
FTSEDKALYDTYLQKENNCE
>M6_Spy0150 tRNA binding domain protein
MIFAYNKEQVGDVLMVILQDTKDIKRQVERKGKVARVFAEESGKTLAWNI
FEASSLITIEGNGQIFLTDEDLARLNAELAKEGFSERLEPTVGPVFVVGQ
IVEMVAHPDSDHLNICQVAIGEDQTVQIVAGAPNAALGLKTIVALPGAIM
PNGSLIFPGKLRGEESYGMMCSPRELALPNAPQKRGIIELDESAVVGEAF
DPAKHWKG
>M6_Spy0295 Hypothetical cytosolic protein
MTVTGIIAEFNPFHNGHKYLLETAEGLKIIAMSGNFMQRGEPALIDKWIR
SEMALKNGADIVVELPFFVSVQSADYFAQGAIDILCQLGIQQLAFGTEDV
IDYQKLIKVYEKKSKQMTAYLSTLEDTLSYPQKTQKMWEIFAGVKFSGQT
PNHILGLSYAKASAGKHIQLCPIKRQGAAYHSKDKNHLLASASAIRQHLN
DWDFISHSVPNAGLLINNPHMSWDHYFSFLKYQILNHSDLTSIFQVNDEL
ASRIKKAIKVSQNIDHLVDTVATKRYTKARVRRILTYILVNAKEPTLPKG
IHILGFTSKGQAHLKKLKKSRPLITRIGAETWDEMTQKADSIYQLGHQDI
PEQSFGRIPIIIKNERLN
>M6_Spy0042 Terminase large subunit
MSGMTTKQRPKINIVIKHPSKVFNKHIYDKLYNYSNFTEVHYGGASSGKS
HGVFQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGIL
DKCKINMSAFRITLPNGAEFIFKGMDNPEKIKSIKGISDVVMEEASEFTL
DDYTQLTLRLRDKKHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQT
TYKDNRFLDDVTRENIEELANRNEAYYKIYALGQFATLDKLIFPKYDKQI
LNKDKLSHLPSFFGLDYGFINDPSALLHVKIDDANKKLYILEEYVRKNLT
NDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIPRMIDVTKGPGTVM
QGIQYLLQYDWIVDERCVKTIEELENYTWKKDKKTNEYTNEPVDSYNHCI
DAIRYAVQDRIYQSADRSKRMKNAKYYF
>M6_Spy0770 ABC transporter permease protein
MRKNMIISSVSQGLIWGVLGLGIYLTFRILNFPDMTTEGSFPLGGAVAVT
AISLGWNPFLSTLLGMLSGALAGFLTGLLYTKGKMPTLLAGILVMTSCNS
IMLMVMGRANLGLHDHKRIQDCLPFSIDLNSLLTGLITVVIVISVLIYFL
YTNLGQAYIATGDNKDMAKSFGINTDWMEVMGLVVSNSLIALSGALVSQQ
DGYADVSKGIGVIVIGLASIIVGEVLYSTGLTLLERLIAIVIGSILYQFL
ISVVITLGFNTSYLKLISALVLALCLMIPVVKERYFKGVRLTR
>M6_Spy1799 Colligrin
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLL
SVITTASQRSDLVILCGGLGPTKDDLTKQTLAKYLRKDLVYDEQACQKLD
DFFAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVL
PGPPSELKSMVNEELVPLLSKQYSTLYSKVLRFFGVGESQLVTVLSDFIE
NQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQLLSRKTLEGQ
PLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPG
ASQVFNGGFVAYSMEEKAKMLGLPLEELKSHGVVSAYTAEGMAEQARLLT
GADIGVSLTGVAGPDMLEEQPAGTVFIGLATQTKVESIKVLISGQSRLDV
RYIATLHAFNMVRKTLLKLENLL
>M6_Spy1561 Terminase large subunit
MYKTNPRRARIVCDGEWGVAEGLVFDNFEVVDFDVEKTIQRVKETSAGMD
FGFTQDPTTLICVAVDLVNKELWLYNEHYQKAMLTDHIVKMIRDKNMHKS
YIAADSAEKRLIAEIKSKGVSGIVASLKGKGSIMQGVQFMQGFKIYIHPS
CEHTIEEFNTYTFKQDKEGNWLNEPIDKNNHVIDAIRYALEKYHIRSNES
NQFEVLRAGFGY
>M6_Spy1189 Transcriptional regulator, biotin repressor family
MKAEDRRQKIIECLNSEQKAVSATRLGKLLGVSRQIIVGDIALLRAQQID
IISTPKGYIMSTALYSHQFCARIVCQHNVEETKKELEIILAHQGIITTVE
VEHPIYGMITAPLNIKTHSDVTNFMSKLSQSKAELLSSLTEGLHSHLISC
PSQEAFLAIKHDLELAGILYKGI
>M6_Spy0849 Short chain dehydrogenase
MKVRKCMGNIALVTGASAGFGRAIVEHLIADGIKVIGASRRLEKLKVLET
SFGSDNFYPLQMDVTDTKAIDDALTSLPNQWQDITILVNNAGLALGLDKA
YEADFENWMTMINTNIVGLIYLTRQLLPHMVSKDDGIIINLGSTAGTIPY
PGANIYGASKAFVKQFSLNLRADLVGSHIRVTNIEPGLCEGTEFSKVRFN
GDEERVKAIYQGAHAIQPQDIASTVSWVIHQPPHVNVNRIELMPVSQSYG
PQPVSRD
>M6_Spy0511 Hypothetical protein
MPAPLKKHNSVEQDDSYQESQSKFRDFQEFNGQSAKLKELVFFARIASFS
LITVLFAFVLLVMNLAPMFAFLFASIISLGITSLLAKVIKSLLM
>M6_Spy0775 ABC transporter ATP-binding protein
MIILQGNKLERSFSGDVLFQNISLQVDERDRIALVGPNGAGKSTLLKLLV
GEETPTSGEVNTKKDLTLSYLAQNSRFESDQTIYEEMLKVFEALRQDEKR
LRQMEMDMATVSGQDLTRLMTDYDLLTEHFRQQGGFTYESDIKAILNGFK
FDESMWQMTIAELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAW
LENYLANYQGALIIVSHDRYFLDKVATVTLDLTPHGLDRYVGNYSRFMTL
KAEKLVAEEKQFDKQQKEIAKLEDFVQKNIVRASTTKRAQARRKQLEKIE
RLDKPTSARKSAHMTFQADKPSGNVVLTVEKAAIGYNQHVLSEPINLDVH
KLDAIAIVGPNGIGKSTLIKSVIGQIPFIKGEVKYGANVEIGYYDQTQSH
LTSSNTVLEELWQDFSTTPEVDIRNRLGAFLFSGDDVKKSVAMLSGGEKA
RLLLAKLSMENNNFLVLDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDR
YFINRLATKVLEITENGSTLYLGDYDYYLEKKAELEELARLAAGETVEET
KEASATDYQLQKANQKERRRLTRRYEEIEARLETIEERIGAIQEDMHASN
DTAQLIAWQKEWDQLDQEQETLMEEWETIAEQIES
>M6_Spy1011 Terminase large subunit
MTIEYDYSAIDDFYKDDAFYYAKMVVDEQIKSSKKVFKACLRHLNDLKKI
DGDNFKFIYLPEKAADPINFIEILPDVKTGKPYPLAMFQKFIIGNLYGWR
KKTDHSLRRFRKAMISVARKNGKTILIAGILLYEFLFGHNPSMSRQLFCT
ANDRTQAKIAWDMAKKQLSSLRAKDADVRKATKIVRDELKNLHDESYIRA
LSRDTGAVDGFEPYVGVLDEFAASKTNEMLELLESGQGQLDNPFILIIST
AGMDLNVPMHTIEYPYITKILDGEITDEGYFGYVAEQDNEEEIKDESNWI
KSNPILEVEALHDKLMDYLRTRRRVSLETGEINKVLIKNFNMWRQSSEES
YIDKTTWELARIDKPDTNKRRVWLGVDVGRVSDLFAITPVVMMDDFWYID
SFSFVATKYGLTAKEKRDGVSYSNLECQGYCEITTLESGVIDDERVLEKI
EEMVYSNDWEINGICFDPYQFGTLLTMIEKRHPEWPLIEVSQTTMVLNMP
TKQFRDDLKKGKIKHSGNPLLTMAVNNAYIKTDNNGMRIDKNKNSNKIDP
LDAALDGYAVCYLEPFDGSGYWTNEKIIGGESLF
>M6_Spy0384 NAD-dependent oxidoreductase
MKLAVLGTGMIVKEVLPVLQKIDGIDLVAILSTVRSLTTAKDLAKAYHMP
LATSKYEAVLGNEEIDTVYIGLPNHLHFAYAKKALLAGKHVICEKPFTMT
AGELDELVIIAKKRKLILLEAITNQYLSNMTFIKEHLDQLGDIKIVECNY
SQYSSRYDAFKRGDIAPAFNPKMGGGALRDLNIYNIHFVVGLFGRPKTVQ
YLANMDKGIDTSGMLVMDYEQFKVVCIGAKDCTAEIKSTIQGNKGSLAVL
GATNTLPQVQLSLHGHEPQVINHNKHGHRMYEEFVAFRDMIDQRDFEKVN
QALEHSRAVMSVLERAVHS
>M6_Spy1786 Glyoxalase family protein
MTYPYNSTISLGKVSLNVTDLAKMTTFYTSIIGLQVLSQDTTSRQLTTDG
KTVILELRQTPLPANKAYGLYHTAFLVPDRHSLGLHFLTRGISLEGAADH
GYSEAIYLSDPEGNGIEIYHDKAVEHWDIRDNGQIIGVTEPTDTKSILEQ
LTDIPKHFLLAQDTRISHVHLSVKNALDSSLLYQKVFDLGDKMTIPSASW
IASGNYHHHLAFNQWSGPYLKKHQEGTPGLAFLTIHIETPLLFSATLKKA
R
>M6_Spy1307 NAD-dependent oxidoreductase
MHGKGVRMAKVRYGIVSTAQVAPRFIEGVRLAGNGEVVAVSSRSLDKAKA
FAAAHQLPKAYGSLDDMLLDASIDAIYVASINQDHFPAAKKALLAGKHVL
VEKPFTLTAAQAEELFALAQERGLFLMEAQKAVFIPMTKRLKSLIAAGEL
GDIVSASSTTAYPNIDHVIWFRDLEKGGGTVHFMAPYALSYLPYLFDTDI
VSASGVAHFPEGQSDSQSKLVLTLSNGVLVDIFLTTHLSLPHELVIYGTK
GRLEIPHFWKTTHATLVRPDGSRSVIEATMSSDFEAEAYHVSQMILEGQL
TSPVMTKSLTLSGVGLIEKLYRSWGK
>M6_Spy0502 Hypothetical membrane spanning protein
MSLFSNLPPSVLQWFAIFMSIIIEALPFVLLGTILSGCIEVFVTPELVQK
YLPKQKCLRILFGTFVGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLAT
APIINPIVLFATYSAFGNSLRFLILRLVGAALVAITLGVMLAFIVDDNIL
KDNAQPVHFHDYSHESLPKRIYLALVHAIDEFFDTGRYLVFGTLIASAMQ
IYVPTRVLTTIGHNPLTAILIMMLMAFILSLCSEADAFIGASLLSTFGVA
PVIAFLLIGPMVDIKNLMMMVKAFKGRFIVQFIGVSVLMIAVYCLLVGVL
>M6_Spy0591 Diacylglycerol kinase family
MKKQLRARLIYNPTSGQELMRKSVPEVLDILEGFGYETSAFQTTAQKNSA
LNEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLKKRPKMAIIPTGTTND
FARALKVPRGNPSQAAKLIGKNQTIQMDIGRAKKDTYFINIAAAGSLTEL
TYSVPSQLKTMFGYLAYLAKGVELLPRVSNVPVKITHDKGVFEGQVSMIF
AAITNSVGGFEMIAPDAKLDDGMFTLILIKTANLFEIVHLLRLILDGGKH
ITDRRVEYIKTSKIVIEPQCGKRMMINLDGEYGGDAPITLENLKNHITFF
ADTDLISDDALVLDQDELEIEEIAKKFAHEVEDLEQELEE
>M6_Spy0128 Bis(5'-nucleosyl)-tetraphosphatase(asymmetrical)
MYFCHQLKANQLLTQSQYFKVVFDIDPIQKGHLLLISKDHYTSLTQLPKE
VRYDLIDLQAALVAKLEQHLPISGVTSVSNDKELMEEGTQFHLHLIPRLT
NDSFWEGITINQENWDLAPFLKHL
>M6_Spy1844 Phosphohydrolase (MutT/nudix family protein)
MTVDASQIQLWGEIDYLVQSSRTIHCFVGQLVVDDWKSIEANEEVDRLFT
VPLQQLLATEPVFYHLEASPLKTSDFPFDRIRHGKDYQFSQQYRSIPFYE
NLEETIWGMTAQFTKCLTDILNDESIAKKNPLDIEKSKGR
>M6_Spy0341 Fe-S oxidoreductase
MCYNRNMKKRYQTLNEHYRQLFGAKMFKVPIDAGFDCPNRDGTVAHGGCT
FCTVSGSGDAIVAPDAPIKEQFYKEIDFMHRKWPDVNRYLVYFQNFTNTH
DTVDVIRDRYEQAINEPGVVGINIGTRPDCLPDDTIAYLAELSERMHVTV
ELGLQTTYEETSRLINRAHSYDLYKETVRRLRHYPNINIVSHLINGLPKE
THDMMLENVRRCVTDNDIQGIKLHLLHLMTNTRMQRDYHEGRLKLLSQKD
YVSIICDQLEIIPKHIVIHRITGDAPRDMLIGPMWSLNKWEVLNAIDKEM
ERRGSFQGCKVD
>M6_Spy0749 HflX
MVKVMIETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMASF
SQKRERYDSKTFIGSGKLDEIKAIVEADEIDAVIVNNRLTARQNANLEAV
LEVKVIDRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGIMLSR
QAGGIGSRGPGESQLELNRRSIRHQIADIERQLTQVEKNRQKIRDRRVGS
DTFKIGLIGYTNAGKSTIMNLLTDDSHYEANELFATLDATTKQLYLENQF
QATLTDTVGFIQDLPTELVAAFKSTLEESKYVDLLLHVIDASDPNHSEQE
KVVLNLLKELDMLNIPRLAIYNKVDIAEQFTATAFPNIRISARSKDSKIL
LRRLIIDQIRDQFVPFRIKVHQDKAYKLYDFNRVALLDHYTFDQEIEDIS
GYISPKQQWRLDDFYE
>M6_Spy1239 unknown phage protein
MTKQHRETLIWYRASHQERERLLDFGLVDKARYVTLLRQLRKKYAI
>M6_Spy1508 Hydrolase (HAD superfamily)
MTVKAVFFDIDGTLLNDRKNIQKTTQKAIQQLKKQGIMVGLATGRGPGFV
QPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSMIYKVIRYANEKKRE
ISLGTASGLAGSRIIDMGTSPFGQVISSFVPKSWARTVEGSFKHLIRRIK
PQSFRNLVTIMREPIYQVVLVASQAETKKIQEKFPHIKITRSSPYSLDLI
SVDQSKIKGIERLGEMFGFDLSEVMAFGDSDNDLEMLSGVGIGIAMGNAE
TVVKDGAHFTTDSNNNDGISKALAHYGLIHFDIEKSFKSRDENFNKVKDF
HRLMDSDTIETPRSYTISEAGYRSGFKVEEIVEFLYAASKGDQQQFTQAI
FDLHGAVDQAANKVQAKKHVETPLIGQVDALADLLYFTYGSFVLMGVDPQ
PIFEAVHEANMAKIFPDGKAHFDPVTHKIQKPDYWQERHAPEVAIKKELD
KQLQKSLQRFDK
>M6_Spy0668 RNA binding protein
MDTIENLIIAIVKPLISQPDNLTIKIEDTPDFLEYHLDLDAQDIGRVIGK
KGRTITAIRSIVYSVPTLGKKVRLVIDEK
>M6_Spy0554 Hydroxyacylglutathione hydrolase
MPFIFRYSFFNKALIFWYTILMKIYKTINHIAGENTYYLVNDQAVILIDP
GSNGQEIISKIKSFEKPLVAILLTHTHYDHIFSLDLVRDAFDHPPVYVSE
KEAAWLSSPDDNLSGLGRHDDIINVIARPAENFFKLKQPYQLNGFEFTVL
PTPGHSWGGVSFVFHSDELVVTGDALFRETIGRTDLPTSNFEDLITGIRQ
ELFTLPNHYRVYPGHGPSTTICHEKNANPFFH
>M6_Spy1269 Pyridoxal-5'-phosphate family protein
MDLLTNKKKIFETIRLSTEAANRTNDGVSVIAVTKYVDSTIAGQLIEAGI
EHIAENRVDKFLEKYDALKYMPVKWHLIGTLQRRKVKEVINYVDYFHALD
SVRLALEINKRADHPVKCFLQVNISKEESKHGFNISEIDEAIEEIGKMEK
IQLVGLMTMAPANASKESIITIFRQANQLRKNLQLKKRKNMPFTELSMGM
SNDYPIAIQEGSTFIRIGRAFFH
>M6_Spy1603 Ribosomal-protein-alanine acetyltransferase
MIVTTLSESNMKTVEEQAKKIYQLLEMVYGTSPWTLEQVLIDIRRDQTDY
FLLYDYDKLLGFLAIQDLSGEVEMTQIAILPSHQGLGLASQLMTHLGSIE
SDIFLEVRESNHRAQGLYQKFGFKFIGKRPDYYRNPIETALLMKREGKHD
R
>M6_Spy0522 Integral membrane protein
MSAKLMSRIAIMSALCVVLRMVFSSLPNVQPVTAFLLSYLLYFGLAEAVL
VMMLCLFLSAFLLGFGPWVFWQVTCFVLVLLLWRFVLYPLSQQFPKYQLG
YQAFLAALCGLLYGVLIDTCFAYLYSMPWWSYVLAGMPFNIAHALSTLVF
FPVVMMLFRRLIGEQKI
>M6_Spy0605 Phenylalanyl-tRNA synthetase beta chain
MGTKIMLVSYKWLKELVDIDVTPAALAEKMSTTGIEVEGIEVPAEGLSKL
VVGHVLSCEDVPETHLHLCQVDTGDETPRQIVCGAPNVKAGIKVIVAVPG
ARIADNYKIKKGKIRGMESLGMICSLQELGLSDSIIPKEFSDGIQILPEE
AVPGDAIFKYLDLDDHIIELSITPNRADALSMRGVAHEVAAIYGKSVSFP
QKNLQESDKATSEAIEVAIASDKVLTYASRVVENVKVKPSPQWLQNLLMN
AGIRPINNVVDVTNYVLLYFGQPMHAFDYDKFEDHKIVARAARQGESLVT
LDGEKRDLTTEDLVITVADKPVALAGVMGGQATEIDGNSQTVVLEAAVFD
GKSIRKTSGRLNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEGQVL
SGHVQAGQLPTEPVEVSTSLDYVNVRLGTELTFADIQRIFNQLGFGLTGD
ETRFTVAVPRRRWDISIPADLVEEIARIYGYDKLPTTLPEAGGTAAELTP
TQALRRKVRGLAEGLGLTEIISYALTTPEKAIEFAVAPSHLTELMWPMSV
ERSALRQNMVSGMLDTVAYNVARKQSNLALYEIGKIFEQEVNPKEDLPNE
VNHFAFAICGLVAQKDFQTQAQAVDFYHAKGILDTLFANLNLKVQYVPTK
DLANMHPGRTALILLDEQVIGFVGQVHPGTAKAYSIPETYVAELDMAALE
AALPSDQTFVEITKFPAMTRDVALLLDREVSHQTIVTAIESAGVKRLTKI
KLFDVYEGATIQAGQKSMAYSLTFQNPNDNLTDEEVAKYMEKITKSLTEQ
VGAEVR
>M6_Spy1141 Terminase large subunit
MTYHYKPSPFMLPTSHYDEKKADRAVAFIQNLKHTKGKWAGKHFLLLPWQ
EQIIRDLFGIVKEDGNRQFLSAYVEIPKKNGKSELAAAIALYLLYADGEA
SAEVYGAACDRNQASIVFDVAKQMVGMSNPLNKRSKIMGATKRIVNYNNA
GFYQVLSAETGTKHGLNVSGLVFDEIHAQPNRHLYDVLTKGSGDAREQPL
FFIITTAGTDKNSICYEFHTKALDILSGRKKDETFYPVVYGLANDEDWQD
EENWYKANPSLGHTIQIDRVREAYRNAIDNPAEENVFKQLRLNMWTSSTV
TWIAEHVYDKGNRPIVESSLLGRECYAGLDLSSTSDITAFVLVFPPRTED
ESYIVLPYFWLPEDTLPLRCRRDHVLYDVWERQGYLKTTEGNVVHYGFIE
RFIEDLSTKFNIKEIAYDRWNATQMVQNLEDMGLTVVPFGQGYKDMSPPS
KELYKLMMEGRVTHAGHPVLKWMAQNVVMRQDPAGNIKPDKEKSVDKIDG
IVALIMGLDRCIRHKGDDGSIYDQRGILSF
>M6_Spy0811 tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase
MSITKEFDTITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKNLEQVAS
HTINYGHIIDPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNE
ILQLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMTI
AVKQLDGSLSQLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREK
TQEFQSLLENLLRTAKRGKILREGLSTAIIGRPNVGKSSLLNNLLREDKA
IVTDIAGTTRDVIEEYVNIKGVPLKLVDTAGIRETDDLVEQIGVERSKKA
LQESDLVLLVLNASEKLTDQDRALLNLSQDSNRIILLNKTDLEQKIELEQ
LPDDYIPISVLTNQNINLIEDRINQLFFDNAGLVEQDATYLSNARHISLI
EKAVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQL
FSQFCLGK
>M6_Spy1066 Transporter, MFS superfamily
MSTLSLDTTNKRALVAAIAASGTDDLNVMFLAFSMSSIMTDLGLSGTQGG
WIATITNLGMLVGGLLFGLLADRHHKFKVFKWTILLFSVATGLIYFTQSL
PYLYLMRFIAGIGVGGEYGVAIAIMAGIVPPEKMGRMSSLNGIAGQLGSI
SSALLAGWLAPSLGWRGLFLFGLLPILLVIWMTLAIDDQKIWDHYGQEEE
ECSQPIKINELFKTKSLTAQTLALMVMTTVQIAGYFGMMNWLPTIIQTSL
NLSVKSSSLWMVATIVGMCLGMLCFGQLLDCFGPRLIYSLFLLASSICVY
LFQFANSMASMVIGGAIVGFFVNGMFAGYGAMITRLYPHHIRSTANNVIL
NVGRALGGFSSVAIGSILDASGISMVMIFLASLYVISFGAMWTIGQLKAE
RYQQLR
>M6_Spy0509 Hypothetical protein
MDLVGISLMIIALAFVALVIFLIIVLKKVSETIDEAKKTISVLTSDVNVT
LHQTNDILAKANILVEDVNGKVATIDPLFVAIADLSESLSDLNSQARHFG
QKATNATGNVSKAGKLALVGKVASKVFGKKGEKHE
>M6_Spy1727 ABC transporter ATP-binding protein
MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGKSTLMNI
IGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTA
CQNVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRV
AIARALVTNPSFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHE
PEVAALCKKTVILRDGNIEHSDIE
>M6_Spy1400 Recombination protein recU
MVNYPHNLIRQKVSSVQKQTKQNKVDFANRGMSFEAAINATNDYYLSRQI
AVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYCGVYKGHYVDFE
AKETRQKTAMPMKNFHLHQIEHMACVLHQKGICFVLLHFSTLKETYYLPA
QALISFYQIDNGSKSMPIDYIRKNGFKVAFGAFPQVPYLNIIEQNFLGGD
YN
>M6_Spy1879 ABC transporter ATP-binding protein
MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFLKILAGD
IEPSTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYNIMKEKD
AIYMKADFSEEDGVRAAELEGIFAELGGWEAESEASQLLQNLNIPEDLHY
QNMSELANGDKVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLID
FENTVIVVSHDRHFLNKVCTHMADLDFGKIKLFVGNYDFWKQSSELAARL
QADRNAKAEEKIKELQEFVARFSANASKSKQATSRKKMLDKIELEEIVPS
SRKYPFINFKAEREMGNDFLTVENLSVTIDGEKIIDNISFILRPGDKAAI
IGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSKDFATEESI
LEWLRQFASKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
KLMLLKSNVLILDDPTNHLDLESISSLNDGIKDFKESVIFASHDHEFIQT
IANHIVVISKNGVIDRIDETYDEFLDNPEVQARVAELWK
>M6_Spy0868 NADH oxidase H2O-forming
MSKIVVVGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGCGMALWI
GEQIAGPEGLFYSDKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKNH
VETYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSAD
VIAKLENKDIKRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYY
DRDLTDLMAKNMEEHGIQLAFGETVKEVAGNGKVEKIITDKNEYDVDMVI
LAVGFRPNTTLGNGKIDLFRNGAFLVNKRQETSIPGVYAIGDCATIYDNA
TRDTNYIALASNAVRTGIVAAHNACGTDLEGIGVQGSNGISIYGLHMVST
GLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYDKDSRRILG
AQMAAREDMSMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
ALGAKD
>M6_Spy0765 Tetratricopeptide repeat family protein
MRRLRTMLNSEKMIASLDQQDLAHAEKYFQKALKEDDADSLIALGEYLES
IGFLPHAKRIYLQLADDYPELNINLAQIAAEDDAIEEAFLYLDKVSKDSP
NYLSALLGMADLYDMEGLTEVAREKLLQAVGISPEPLVIFGLAEIDMSLQ
YFKEAIDYYAQLDNRQILELTGISTYQRIGRAYASLGKFEAAIEFLEKAV
AIEYEDETVFELATLMYDQENYQKANLYFKQLETINPDYPGYEYGYALSL
HEEHKTSEALRLVQQGLRKNAFDSQLLLLASQLSYELHDRQNAENYLLQA
KEVAVDDEEILMRLVTLYFDAERFEEVIALNRETIDNVLTKWTIAKAYHA
LEQEEVALALYNEISADLAENPEFLQDYAYLLREFGQFHKAIQMATAYLR
QVPDDVNMQDFLDHIKHQQSE
>M6_Spy1470 ATP/GTP hydrolase
MFYSENEYTLKAYGETLGTYLSIGDVIVLSGDLGAGKTTLAKGIAKGMGI
SQMIKSPTYTIVREYEGRLPLYHLDIYRVGDDPDSIDLDDFLFGNGVTVI
EWGELLGEGLLQDYLQITITKRDKGRQLDLLAHGERSRQLLEIISHDSAK
SRY
>M6_Spy1388 Hydrolase (HAD superfamily)
MVNIILLIVSALIGLILGYALISIRLKSAKEAAELTLLNAEQEAVDIRGK
AEVDAEHIKKTAKRESKANRKELLLEAKEEARKYREEIEQEFKSERQELK
QLETRLAERSLTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQLQVEK
LEEEKKAELEKVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDR
TVKTAKDLLAQAMQRLAGEYVTEQTITSVHLPDDNMKGRIIGREGRNIRT
LESLTGIDVIIDDTPEVVILSGFDPIRREIARMTLESLIADGRIHPARIE
ELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPDLIKIMGRLQFRTSFGQN
VLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDREVEGSHVEI
GMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGARN
ESMENYIKRLRDLEEIATSFDGVQNSFALQAGREIRIMVQPEKISDDQVV
ILSHKVREKIENNLDYPGNIKVTVIREMRAVDYAK
>M6_Spy0549 Beta-phosphoglucomutase
MLMIKGIIFDMDGVLFDTEPFYLRRREDFFKTKGIPIDHLNSKDFIGGNL
QELWKELLGKNRDDAIVKAITTDYDAYKQAHKPPYQKLLITEVNSCLEQL
KKQGIKLAVASNSKRQDVLLALETTQIKDYFEIILAREDVSRGKPYPDIY
NKAVQKLGLQKKQLLVVEDSQKGIAAAKAANLTVFAITDYRYGIDQSQAD
HKIDHLGQLCVKIGCFGS
>M6_Spy0750 Cystathionine beta-lyase
MNNYIDLAKTYGGFTSLDTNYLNHLLASLTDQQKLAFITPPPSVINAYFA
EIYQKQSPQAATDYYFNLSKALGLFTDQPSFEEEKPFVRLNLSGKAYGFA
YQNDQEVALVFSEKAEPKKPELFFELTQIFPQYMVYEDKGQLKMQAKQFE
QGECEDITPDDTLLSKIYRLANGITMLKGFNVEELWALSQTFSGQKYYDF
DQREFMIYITQ
>M6_Spy0510 Hypothetical exported protein
MEKKEKSMNKSFKNLVIGAVSGVAAAYFLSTEKGKALKNRAEKAYQAYKE
SPDDYHQFAKEKGSEYSHLARDTFYDVKDKLASGDLTKEDMLDLLKDKTT
AFVQKTKETFAEVEAKEKQDDVIIDLNEDDIIIDYTEQDEPVSDTLDKH
>M6_Spy1659 Hypothetical cytosolic protein
MKKRILLVDGYNMIAFWQSTRQLFKTNQLDQARNTLLTKLNHYAHFENIN
IICVFDAQYVPGLRQRYDQYYISVVFTEEDETADSYIERMAAELNTAIHM
VEVATSDLNEQWTIFSQGALRVTARELEQRVHTVKADLDKMSRDIDLKTP
KLRPFDQGQLSQLKDFMSQLDR
>M6_Spy0255 GTPase
MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVDFSAEDN
SEGYILAIHPRKNSLVRPPIVNIDQAVVIMSAKEPEFNSNLLDRFLILLE
HKAIHPVVYISKMDLLDSPEEIKAIGRQYQAIGYNFVTSLEELLPLLADK
ITVFMGQTGVGKSTLLNRIAPELALETGEISDSLGRGRHTTRAVSFYNTH
GGKIADTPGFSSLDYDIANAEDLNEAFPELRRLSHKCKFRSCTHTHEPKC
AVKAALETGELWPVRYEHYLQFLSEIENRRETYKKVIKRK
>M6_Spy0588 Endonuclease/Exonuclease/phosphatase family protein
MINKKCIIPVSLLTLAITLTSVEEVTSRQNLTYANEIVTQRPKRESVISD
KTNFPVISPYLASVDFGERKTPLPTPDKGVKVTTEQSIAQVRKGPEERTY
TVTGKITSVINGWGGYGFYIQDSEGIGLYVYPQKDLGYSKGDIVQLTGTL
TRFKGDLQLQQVTAHKKLELSFPTSVKEAVISELETTTPSTLVKLSHVTV
GELSTDQYNNTSFLVRDDSGKSIVVHIDHRTGVKGADVVTKISQGDLINL
TAILSIVDGQLQLRPFSLEQLEVVKKVTSSNSDASSRNIVKIGEIQGASH
TSPLLKKAVTVEQVVVTYLDDSTHFYVQDLNGDGDLATSDGIRVFAKNAK
VQVGDVLTISGEVEEFFGRGYEERKQTDLTITQIVAKAVTKTGTAQVPSP
LVLGKDRIAPANIIDNDGLRVFDPEEDAIDYWESMEGMLVAVDDAKILGP
MKNKEIYVLPGSSTRPLNNSGGVLLPANSYNTDVIPVLFKKGKQIIKAGD
SYKGRLAGPVSYSYGNYKVFVDDSKNMPSLMDGHLKPEKTNLQKDLSKLS
IASYNIENFSANPSSTKDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPT
DDGTTDATQSAQRLIDAIKKLGGPTYRYVDIAPENNVDGGQPGGNIRTGF
LYQPERVSLSDKPKGGARDALTWVNGELNLSVGRIDPTNAAWKDVRKSLA
AEFIFQGRKVVVVANHLNSKRGDNALYGRVQPVTFKSEQRRHVLANMLAQ
FAKEGAKHQANIVMLGDFNDFEFTKTIQLIEEGDMVNLVSRHDISDRYSY
FHQGNNQTLDNILVSRHLLDHYEFDMVHVNSPFMEAHGRASDHDPLLLQL
SFSKENDKAESSKQSVKAKKTSKGKLLPKTGDSLVYVITLLGTASLLVPI
LLLTKGKKES
>M6_Spy0555 (R,R)-butanediol dehydrogenase
MTKKYEVEDMSKVAIVTGAGQGIGFAIAKRLHADGFKIGILDYNEETAQA
AVDKLSPEDAVAVVADVSKRDQVFDAFQKVVDTFGDLNVVVNNAGVAPTT
PLDTITEEQFEKAFAINVGGTIWGSQAAQKHFRELGHGGKIINATSQAGC
EGNPNLTVYGGTKFAVRGITQTLAKDLASEGITVNAYAPGIVKTPMMFDI
AHEVGKNAGKDDEWGMEQFAKDITLKRLSEPEDVANAVGFLAGDDSNYIT
GQTIVVDGGMVFH
>M6_Spy0857 4-oxalocrotonate tautomerase
MPFVTIDLFEGRSQEQKNQLAREVTEVVSRIAKAPKENIHVFINDMPEGT
YYPQGEMKQKS
>M6_Spy0478 Hypothetical protein
MSRNPDCKNILIIGFGKIGKIKAYKWLSRGYEVYVKDLKFSSMKYLNTNS
DVLDDLSRQYFTIEICTPTNHHLTLLKTVITRYVYSYISIEKPLCNRLED
LEEMKSLVESHPHLAKKIFASEQYFFSKILEKLLQVDCFSLDKIKEITVN
FSKDRIEDNENGRFLDKEILGYGIEIPHIIAVISYLGISLEEFKKGIFVN
AIYIKDLEKHDYSIEILSCINQTVIKIISNLGSFAIREGKIEGGDAKTVR
RVTIDDKTILFDPHPKLERYKSELVTGTNTFQIHDDMMDTYISLLEGNAI
PEDCYINNAIEITKLLINLYSECEKIYL
>M6_Spy1789 Acetyltransferase
METRRPTLKDKDAVLSMINEFLEQKSATDGLWHFNVNDFNYETWLEDSLR
QEMGLASQGVPAIQYVAFDEKNQALGFLNLRLRLNASLLEKGGHIGYSVR
PSQRGKGYAKEMLKQAVSCAISKNITTILVTCDETNVASRAVIVANGGVL
EDSRGGTERYWIEEQRGDK
>M6_Spy1320 SAM-dependent methyltransferase
MVTKEVGHDFLARLGKKRLRPGGVEATNWLIEQGQFSQDCHVLEVACNRC
TTAIELAKTFGCQIDAVDLNPKVVKEAQERVAVEGLTRHITVSQANALSL
PFPDNHFDIVINEAMLTMLNAQAKEKALNEYWRVLKPGGRLLTHDVAYED
PKTRQVLDELRQTIHVNVAPLSLTGWQALYQEHGFSQVTYHHGKMSLMTP
RGMIKDEGLMNTLNIMRRGLKKENRQQFLKMRRFFTRTGKNLCYIAVKSV
K
>M6_Spy1110 Oxalate/formate antiporter
MEKTKRYIIATAGILLHLMLGSTYAWSVYRNPILQETGWDQAPVAFAFSL
AIFCLGLSAAFMGNLVEQYGPRLTGTVSAILYASGNMLTGLAIDRKEIWL
LYIGYGVIGGLGLGAGYITPISTIIKWFPDKRGMATGFAIMGFGFASLLT
SPIAQWLIETEGLVATFYLLGLIYLIVMLFASQLIIKPTAAEIAILDKKR
LQNNSYLIEGMTAKEALKTKSFYCLWVILFINITCGLGLISVVAPMAQDL
TGMSPEMSAIVVGAMGIFNGFGRLVWASLSDYIGRRVTVILLFLVSIIMT
ISLIFAHSSLIFMISIATLMTCYGAGFSLIPPYLSDLFGAKELATLHGYI
LTAWAIAALTGPMLLSITVEWTHNYLLTLCVFIVLYILGLMVALRLKK
>M6_Spy1372 ComF operon protein 3
MICLLCQQISQTPISITEIIFLRRISSPICQQCQKSFQKIGKSVCATCCA
NSDIIACRDCLKWENKGYNVNHRSLYCYNAAMKAYFSQYKFQGDYLLRKV
FAVELADVITKYYKGYIPVPVPVSPGCFRERQFNQVSAILEAANVSYLSL
FEKLDNTHQSSRTKKERLLVEKSYRLLKVSNIPDKILIVDDIYTTGSTII
ALRKQLAKVANSDIKSLSIAR
>M6_Spy0309 Hypothetical cytosolic protein
MMLAISEIRKHPDGLSFDRLCDVKSMLLERDQQIIDIKAVKAVGNVRYDK
GLYLLDYQLSYEVILPSSRSMVPVCLSEVQHIQELFIEATDLADKKELVE
DNLVLVLDKDAINLEESIVDNILLAIPLQVLTEEEKKSKELPAGQNWAVL
TEEDYQCLKEEKQKENNPFASLQGLFDE
>M6_Spy0862 Phosphinothricin N-acetyltransferase
MLRPLSKTDCPMLQEINAKALGYLVSLDLLERQYERLIEDCHHYFLAYAD
KDTNQLLGYVHAERYETLYASDGLNLLGLAVLPAYQRRGIGSALLRALES
QAKQEGIAFIRLNSASHRKEAHAFYQNLDYADDKTQLRFIKNLQGDDNDF
>M6_Spy0640 Methyltransferase
MNKLYIDSFVEKKLTAGVQLLDEKDFSNIKEKNQLVQLVTKSNRPIGTAY
ISKQNKGIGWYLGPEKIDLSISYFVSLFSVAKAKRQDFAQSDETNAYRLF
NQEGDGFGGVTIDLYKDFAVFSWYNAFVYDKKEMIMEAFQQVFPEVKGAY
EKCRFKGPDTETAHLYGELAQETFSILENGIAYQVFLNEGLMTGIFLDQH
DVRRALVDGLAMGKSLLNLFSYTAAFSVAAAMGGAIETTSVDLAKRSREL
SLAHFEHNQLNLASHHFVVMDVFEYFKYAKRKKLIFNVIVIDPPSFARNK
KQTFSVSRDYHKLITEALDILSPKGTIIASTNAANMTVSQFKKQIIKGFG
SRRPESMTLQQLPSDFTINKADERSNYLKVFTIKVRE
>M6_Spy0457 ABC transporter permease protein
MAKLRRMHAIFIKQYLKQIMEYKVDFVVGVLGVFLTQGLNLLFLSVLFQH
IPSLEGWTFEQIAFIYGFSLIPKGIDHLFFDNLWALGQRLVRKGEFDKYL
TRPISPLFHVLVETFQVDALGELLVGVILLVTTAGSIVWTLPKVLLFILV
IPFATLIYTSLKIATASISFWTKQSGAVIYIFYMFNDFSKYPMSIYHSFL
RWLISFIIPFAFTAYYPASYFLTGQHLLFNIGGLVVVSLLVLALSLKLWK
WGLGAYESAGS
>M6_Spy0081 Hypothetical cytosolic protein
MELREFKAWLLKNHFEEDELYKESIKCYQVEAYKAAYIFSYLANHKFIAK
LAIDYSGVSSNFMSKCPDDEVRKSSWQKRVNSLKNEDEWEQTVNEKLIQA
WEDDNVFKLPFKIKEKYSLMRVLRNNAAHAKDCRISESTVLELWNEIEYI
YPYFVINGTIDAWMEDLEKLVRYSNSSIESQNQLQNKFGDFSTENKTLIV
KKIIQKYLVDSEWDETYPDIVMNFLLYIFQESNYINQIGKDLTEKEELYL
SIGTGIYHFQAEAIDIYSQFEESLSDYTFRYFCEEFSDNFWKFIDSMDSE
VNKENLTATSLEILKKNSAILVNAEFNESRFLSDNSLFFKSVLDKIKHLY
YYTMHHTGQRHHNTNTFDYSKFNSYIPYINYIFYRISSNPGLKEDEKVID
FVKRCNNLISSDYSAESWYSERQMQDVIKKINEKYTILEDSGRESD
>M6_Spy0320 Aminodeoxychorismate lyase family
MALTDFKDKDQQDQQRSFKEQILAELEKANQIRKEKEEELFQKELEAKEA
ARRTAQLYAEYKRQDAFQKESIAHNNKTAKHFQAIKDAVMTSEAIKPTLL
SEKENSSLKTTSKRVVQANELQETASKESQVPLTIEKGHSVRRKLSKRQQ
TERAAKKISTVLISSIIITLLAVTLAGAGYVYSALNPVDKNSDAFVQVEI
PSGSGNKLIGQILQKKGLIKNSTVFSFYTKFKNFTNFQSGYYNLQKSMSL
EEIASALQEGGTAEPTKPSLGKILIPEGYTIKQIAKAVEHNSKGKTKKAK
TPFNEKDFLDLVTDEAFIQDMVKRYPKLLATIPTKEKAIYRLEGYLFPAT
YNYYKETTMRELVEDMLAAMDATLVPYYDKIAASGKTVNEVLTLASLVEK
EGSTDDDRRQIASVFYNRLNSGMALQSNIAILYAMGKLGEKTTLAEDATI
DTTINSPYNIYTNTGLMPGPVASSGVSAIEATLNPASTDYLYFVANVHTG
EVYYAKTFEEHSANVEKYVNSQIQ
>M6_Spy0752 Short chain dehydrogenase
MAQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQHIDNKE
CLELDITNPVAIEKMVAQIYQRYGRIDVLINNAGYGAFKGFEEFSAQEIA
DMFQVNTLASIHFACLIGQKMAEQGQGHLINIVSMAGLIASAKSSIYSAT
KFALIGFSNALRLELADKGVYVTTVNPGPIATKFFDQADPSGHYLESVGK
FTLQPNQVAKRLVSIIGKNKRELNLPFSLAVTHQFYTLFPKLSDYLARKV
FNYK
>M6_Spy1295 Acetyltransferase
MTDKFDANDETRTVYAVVYDNDQPVSTGQFLAETKIEARLTRIVTLADYC
GCGYGAKVTEALETYTRREGFYQLTIHSELTAQTFYENLGYQTYGSKYLE
DGEYCQSLVKTILKWEKNMDIAMLIAIVGGLLGCYLYLTKNNEPKD
>M6_Spy0757 Hypothetical cytosolic protein
MDSQLSNRLAQVAAYVPKGVKLLDVGSDHAYLPIFLVETNQISAAIAGEV
VRGPYESALKNVTQSGLAEHIQVRLANGLAAFEEADDVTAITICGMGGRL
IADILEAGKEKLQGIERLVLQPNNREDDLRAWLSVNAFKIVAETIMAEND
KYYEIIVAEHGEKALSATELRFGPYLSQEKSVVFKEKWQREMDKLAYALS
CIPEEKTQERQLLLTKIQQIKEVIVHES
>M6_Spy1707 Acetyltransferase
MIPIKALKIKVETVMKIIEYKGNYRDDLIFMVLEAKNALRRIPSINPDLL
TIETSYLEKGDCFWLAVNEESRVIGSIAYSSIPKTNEVFLHRLFIKPSLK
HQGIGSQLLTFAEDYLRKIGKSHVRIHLGQPKEQWFESYRFYPKHGYQFY
DDTHLIKKLI
>M6_Spy1657 Hypothetical membrane spanning protein
MSCKDLKEKRIMFDSKQNLAKSQWMFIIIIAVMDLVVLVATLLAKTSFQR
YLVGGVAVILTSFLILLVWGLKTAKKLQTRLDSKEVLDSKVRDDQKLPKY
DERQKQILLKGYTIGFWFMIVVIWLSLFISRFTEGLVSASFLFTLALWGG
LAVQTTYCNLNGASSFVDRRFGKQGILMGMIATGMSLVTIGLAVREMMAG
QLKMGSFFKAGGSGSLMVLGITLLSMGASIFYRHYLDAKEADE
>M6_Spy0834 Class B acid phosphatase
MKKEFTSILFTVSFCGIIALPVEASGPKVPYTQEGITAISNQATVKLISI
ADIASSLEGQKPITVSFDIDDTLLFTSQYFQYGKEYITPGSFDFLHKQKF
WDLVAKRGDQDSIPKEYAKQLIAMHQKRGDKIVFITGRTRGSMYKKGEID
KTAKSLAKDFKLDKPIAINYTGDKAVKPYQYDKTYYIKKNGSQIHYGDSD
EDINAAKEAGARPIRILRAPNSTNLPLPKAGGYGEEVLENSAY
>M6_Spy1486 Enoyl-[acyl-carrier protein] reductase (NADH)
MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGGNAPKEV
VKANIDRVKAITDRPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPG
KYMERLHQAGIIVVPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTT
MSLVRQVVEAVSIPVIAAGGIADGHGAAAAFMLGAEAVQIGTRFVVAKES
NAHQNFKDKILAAKDIDTVISAQVVGHPVRSIKNKLTSAYAKAEKAFLIG
QKTATDIEEMGAGSLRHAVIEGDVVNGSVMAGQIAGLVRKEESCETILKD
IYYGAARVIQNEAKRWQSVSIEK
>M6_Spy1174 COME operon protein 3
MTFSWTKLVPLSKIQFAFLILVLFYQIHSPSWLTFLLSLSLICLLVKRLS
KKEFLGVFAILSFCALFLLYQKQQLVQKLEIQPVQITSVALVPDSIRING
DQLAVLGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVMHAKVTLEKAEEV
RNFKGFNYQTFLAYQGIYRIGKVEQIEQLEVISPKSICDYLSSLRRRAIV
HCQQHFPSPMSHYLTGLLFGYLDKSFGEMTDYYSQLGIIHLFALSGMQVG
FFLTCFKRVLLLLAVPLEWIKWIELPFACFYAALTGYSISVIRSLVQSQL
RHLGIKGLDNLACTFLLVFLWDAHFLMTVGGVLTFSYAFLLTVVTVEELS
GAKRQLVQVLTISLGILSFLLFYFSSFNPMSMVLTALLSYFFALFILPLL
CLVFCLSPLITLSGCNYLFLFLEKVIQFLGNTFNSSLVFGSPTSWHLLIL
VISFAIFYDYRQVRQRVITCGLVIALTLLSVKYPLTNEVTFIDIGQGDSI
LVREWTGKNLLIDVGGRPLKIRAL
>M6_Spy1866 Zinc protease
MTKLVKINYPNIDEDLYYVKLENGLTVYFIKKIGFLEKTAMLTVGFGSLD
NKLTVDDESRDAPAGIAHFLEHKLFEDESGGDISLKFTQLGAETNAFTTF
NQTSFFFSTASKFQENLELLQYFVLSANITDESVSREKKIIGQEIDMYQD
DADYRAYSGILQNLFPKTSLANDIAGSKESIQKITKILLETHHTYFYQPT
NMSLFIVGDIDIDETFLAIQRFQTTLSYPDRKRVTVDPLHYYPVIKSSSV
DMDVTTAKLVVGFRGYLTLTQHSLLTYRIALKLFLSMLIGWTSKIYHTLY
EDGKIDDSFDVDVEIHHNFQFVLISLDTPEPIAMSNYIRQKLATIKISKE
FTNEHLNLLKKEMYGDFIQSLDSIEHLTHQFSLYLSDSDKETYFDIPKII
ERLTLKDVVTIGKAFFEKADASDFTVFPK
>M6_Spy0671 Hypothetical cytosolic protein
MITQEMKDLINNQLAMVATVDAKGQPNIGPKRSMRLWDDKTFIYNENTDG
QTRINIEDNGKIEIAFVDRERLLGYRFVGTAEIQTEGAYYEAAKKWAQGR
MGVPKAVGIIHVERIFNLQSGANAGKEINSESN
>M6_Spy1777 Transcriptional regulator, LuxR family
MTKGIRFQLLGSPHIFLDDKEQFFAFAKANALLYYLVVNGSVSREVAASL
LWENKNTQTAKKNLRNAIYQVNKVLQADVIICPNRNLLVLNKTLDIKTDI
NLFLADPLAHLELYQGEFLQGFYLKSGEEFDLWVSKMRMQYEQVYLKACY
QKIEEKLSLDAIEDVEEHLKQLIERDEFEEKNYQLLMRLYQQGNCPGKVI
ETYYQLANVLDKELGIQPSLQSQQIYQEVVAKDRNERKIKYFLRNSNHFL
GRIDEIKQLENYFANCLACQEVGALLLIGDTGIGKRTLARQVLANQTQTF
QIVTAKCFREEAMDSLLPWRNILDGLGDLVIQNRLLTTKAWKAALKRCFP
AATIFQEDNNQPFIKDHTSLLVSFIVDILQHLAEIKALVILIEDCHWMDE
DSLTLLQRVMNQLVHYPIAFVLTKHLGTTPELGLCLNALMSQGRLESICL
EPFNRQESLAYISSQLGSQPVTEEEMEHLYQASQGNPFFLSEYTQALLRH
EKFVPLTPAIKAKLGLKLANLSSRDDALLNYLSCCRRPIPLNTLAQLMLL
PLEEVIEMVDNLGHYYILVEESVGEEVLISFRQRIIQLYSYDRLSLSKRR
LLHGQIAKRLEDLLPILTPSPHLLDDIAYHYQESRQVIKALEYNLNYLDA
TLPFQHELFPIYSKSIGSLEKSDRDHQRLMEEQFDKIRQSIADLELTYDN
NRDFQQLLIRFSYLEGRYDIRTGRYQEGIKHIQKVIALATELKQPSFLLE
GYRQLIHYCIQVENKPEMRYYTSLSLEAAVAANHFEAIAISLRLNGLYHL
IIGELNEAERLLQQSIDFFKVTPGLQANYATQIAAALDYLGEIAQIRYQF
EKAVAYQKQAIALTENKPAELSVSIFYIGLGISYFYLADFEQAEQILSLA
KEALVNHSYPWKETQLEIYLAMIQWKKGNYQPALTLLDYRETLMSRYRNP
RDKGLVFYLMAVVKYQLIFQGATLSQQEKEMADHLLSESFEYYYEIASTN
LNPYRDCHLVSELDGLRQQFSSNN
>M6_Spy0533 Hydrolase (HAD superfamily)
MSIKLVAVDIDGTLLTDDRRITDDVFQAVQEAKAQGVHVVIATGRPIAGV
ISLLEQLELNHKGNHVITFNGGLVQDAETGEEIVKELMTYDDYLETEFLS
RKLGVHMHAITKEGIYTANRNIGKYTVHESTLVNMPIFYRTPEEMTNKEI
IKMMMIDEPDLLDAAIKQIPQHFFDKYTIVKSTPFYLEFMPKTVSKGNAI
KHLAKKLGLDMSQTMAIGDAENDRAMLEVVANPVVMENGVPELKKIAKYI
TKSNNDSGVAHAIRKWVLN
>M6_Spy0184 Nucleoside-binding protein
MNKKVMSLGLVSTALFTLGGCTNNSSKQTTDNSLKIAMITNQTGIDDKSF
NQSAWEGLQAWGKENKLEKGKGYDYFQSANESEFTTNLESAVTNGYNLVF
GIGFPLHDAVEKVAANNPDNHFAIVDDVIKGQKNVASITFSDHEAAYLAG
VAAAKTTKTKQVGFVGGMEGDVVKRFEKGFEAGVKSVDDTIKVRVAYAGS
FADAAKGKTIAAAQYAEGADVIYHAAGGTGAGVFSEAKSINEKRKEEDKV
WVIGVDRDQSEDGKYTTKDGKSANFVLTSSIKEVGKALVKVAVKTSEGQF
PGGQITTFGLKEGGVSLTTDALTQDTKKAIEAAKKAIIEGTITVPEN
>M6_Spy1697 Exodeoxyribonuclease III
MIGNSHSWFRPYGSSCLIKGGLMTKVLTLNTHSWMQANTLKKLVALAEHI
LAEKYDIICLQEINQLIESELATDLPRYQALSGTPSIHKDHFALLLIHYL
QKRGQHYYWSWAYNHIGYDIYQEGVAILSKQPIHVSDILVSAMADETNYH
TRRSLIAKTTLDGKEVAVVNVHLSWFDKGFLGEWEKLEKELLTLNCPLLL
MGDFNNPTDQDGYQVMMGSPLDLQDSHKVADHVFGDHSIVADIDGWQGNK
EALKVDHVFTSKDFIIRSSKTTFEGGDAPVVSDHYGLEVTLGWR