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# Brucella melitensis biovar Abortus, 2308

>BAB2_0149 Flagellar basal body rod protein:Flagellar basal-body rod protein FlgC
MSSDALQSTLKIAASGLSAQSTRLRIVSENIANAQSTARTADTDPYRRKT
VSFRTELEQGTGAAEVRVAEVGKDTSPFIEQYDPSHPAADARGYVKYPNV
NMVVEMADMREANRSYEANLQVVRQARELISMTIDLLRST
>BAB1_0260 Flagellar protein FlgJ:Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase
MTPIGNRNFQNFSKLLPIVSAQPFVWGGDGSKKTPEQLDRERRLAQAMID
RGIDFSPVGHWTQGAARMMSALAGNIKQARADNAEKAGIEGAAKKFAGLD
LGSLLSGGAAYPSAVAGGASPTSGAATGTTPTTGATVDLSGDKQKFIDTL
LPAAIEHGQRIGVDPRIIVAQAAQETGWGRSAPGNNFFGIKSHGQGGGQN
LTTHEVINGQRVKINDSFRTFASPQDSVAGYADFIASNKRYRPMREAQGL
DAQLQALGASGYATDPNYARSVGAIARSINLPQQAQPQGVQVASLDPSIG
MAQAYAPEPQPQTAAAAINQIAPQQPVPEAKISDALLRQNDMALGGALAP
QGQAPQQVADTSGYFPAAPSADSAPIMGSYAAPRQGGVNIQRLLEAASDP
WMNDAQRSVIGMALQQQMQQNDPMRALQAQKLQLEMDALRAKPQTEYGFT
TLPDGTVLRTDKRSGNAEPIYSAGQKPTSDMQEYNFAVSQGFKGSFADYQ
QAMKKAGASSTNVSVGEGDKFYEALDKKNADTFAALSDAGIQARSKLAQI
ERLGGLMQASPTGATAVLKLAAGEYGIKTDGLDDLQAAQALINELVPQQR
QPGSGPMSDADLALFKQSLPRIINTPDGNQLILDTMRGITQYQIQMGDIA
DQVANREISAAEGRNRIKNLKNPLEGFRTSTKDKTPGKSGVSGNRLRFNP
QTGDFE
>BAB1_1043 
MASKSKAQELDLEVEKALEQALDIDFGDDIDIDMDLGAFDEGFSIDDLEE
QISRAAEELVAEQQAKAAEPVGNEPVVKAASVITTASVIATPAAPPVPPV
VKAASSAPAIAANTEHKPANVVAEPVSAQETAAKPAAAVATATPVATPVR
TPANDDSRSDKAIAAAPRRITEHSSKLYWTTTAISVLWAAGGVAISKAIN
PEVFSSLQATKDFFTAPAGLGVVAGVALPIAMFWGFAQLVKRAQEMQDAA
RSMTDAALKLLQPEAVAGDRVSTLGQAVRREVAAMNEGIERTLARAVELE
TLVQSEVNQLERAYSDNEVRIRSLVSDLGNEREAVVSHAERVRSSISGAH
EQLREELSSASNIIRDNVLSASQQLSALLGDSGERLISNINESGGAIADA
IEKRTGDIGNRITTSGEAFANLLDTRIATLDEQSRTISGKLTQALDERTT
GIANVLGSATQTMVSEFDTRLANLENTLSDRGRSLLAEFEARAHALDNST
EKLNAALETRSRQINENLIARTREIAETFSGGRNSLGAMVDDIKVKIGDD
LTSISESVGNVLIDKAAAFEGKLAESRDLLAATLEGETERVSSVIRGHAD
TLAARTGDIQNAIDASASALNEVTDKHAAILTERTSALQQAMSSNVSLLD
ASFADHARSLEERTASLHNVIAGNQAMLAQLMDERAAAMRENFNENREVL
ARTFDERIGSLQSLIAENQSALERILDERARNMAESLGAGRDAFETALGE
HVRTVEERTSGLQAVLNNHNDALAHVLDGHEQTIETRAAEIRSTLTDSTA
SLSQTLQDHGEILEQRTTSLQNAIANSSAAISSAFEGQTGIIEERTETME
KALSIGVDNVRRALEQSAGVVAGKLREKIGEAASTLAAEAAKAGEALDGF
GESFSARLIDNLSGTEARLGERADAIAGRLGDIESRLTDELGTIEARIAD
TAAKTSETLASHSESFSASVADNLAGTETRLVERADAIATRLGDIGSRIT
MELGSVEARIAQVTDTTAVTLEERTRELNAVLAARSQEITKILNDTAEPL
VQRLADSGRGLAQQLEEATHAATDRLRSENAALVNALASRTAETIAAVQQ
AKVGLSDNVSELIDRLAASNGELGKLIDAATRNLADIDGRLVDSTTSFVE
NTNRAAQMFQASTGLIDSNLGTLRTLSDNTLSQIADIADRFDEHGKVLSS
ASDMINSAQNGLVSTLEERHQALDKLASGLVEKSEGVEKLMQSFEALVAS
AFQRAEGQTRVSAEKMRESVSDIVEQAAQKFSAATDEIRRTASEIRAELD
TTRGELKRGVLDMPAEAKETTTAMRKAVSEQINALKELAEIVNKSGRLVD
VGEGRADRPVSRPAASRPAPVRAPIAPLAQTDVAVRSRPVEAPNQKPAPA
ASAEKPRGWVSDLLARASREEEEAAQPKVQPAATPRSPSHVVESLNSLSV
DIARAIDHEASVELWDRYRRGERNVFTRRLYTLKGQQTFDDIKRKYQTDG
EFRRAVDRYMNDFQRLLEDVARNDRDNMVTQTYLTSDTGKVYTMLAHASG
RLR
>BAB2_1101 Flagellar hook-length control protein
MLLTASGRLASLARNSSTQARVAGDEQDGGSDPATLFGALLEKPHGKVDA
SGKDEAEAKSDEKEAGDGSGQKPVAVFGLPQNLLSLASALPGQQHGEGGF
SVEEKAGNPACAAVSEPGMVDVVDPAGIDKAAAEFAGDDEKRPLRELPRV
KAAQTNGDPAIRAGQASGEAALDISGDISGNKLAEGAAADVAGIKAPKPA
TDHKPAKGMDVRADLLPQQAAAKSTVPAEAKAAAGMPEAARIADIEVVSE
RSFGTVKTLQIRLDPVELGAVTARIRVAGDSVEVHLVADKSHAAEMLAAD
RSMIEKALKVAGVGDDTKISVTVADRNAQGAAQHVAAAQNAGQQQASAQQ
QGHQLAFNMQQQGSQGRGGEAQAQFMSGRSGGEGGRNGGSGQAGREHANS
QAKPENGRGAPHIGGRGLVV
>BAB2_0058 Bacterial type II secretion system protein E:ATP/GTP-binding site motif A (P-loop):Sigma-54 factor interaction domain
MMSNRSDFIVPDEAAVKRAASVNFHLEPLRPWLDDPQITEVCVNRPGEVF
CERASAWEYYAVPNLDYEHLISLGTATARFVDQDISDSRPVLSAILPMGE
RIQIVRPPACEHGTISVTIRKPSFTRRTLEDYAQQGFFKHVRPMSKSLTP
FEQELLALKEAGDYMSFLRRAVQLERVIVVAGETGSGKTTLMKALMQEIP
FDQRLITIEDVPELFLPDHPNHVHLFYPSEAKEEENAPVTAATLLRSCLR
MKPTRILLAELRGGETYDFINVAASGHGGSITSCHAGSCELTFERLALMV
LQNRQGRQLPYEIIRRLLYLVVDVVVHVHNGVHDGTGRHISEVWYDPNTK
RALSLQHSEKTQ
>BAB1_1725 conserved hypothetical protein
MSDMRESLVRERLDEGRDYDPYRLSSPRVVILSMLIFLIIVAFLAAILMR
QIHTFFVTNPGLNGLILGVLLVGILLAFGQVLRLLPEIRWVNSFRDGDRE
GTARPPVLLAPMRALIGRRQSMALSTSSMRSILDSIATRLDESRDISRYL
IGLLVFLGLLGTFWGLLETVGSIGRTIQTLDPNSGSTGDVLDALKAGLQA
PLSGMGTAFSSSLFGLSGSLILGFLDLQAGRAQNRFYTELENWLSSVTDL
GSDLSGDHHGSTDEIRVLADRLHNLHGDDASTQRTTAALANLAEGIQGLV
KSMRNEQQMMRDWVEKQADEQKAIRHSLDRLSKAMGERQHRPERTDKPE
>BAB2_1098 Flagellar basal body rod protein:Trypsin inhibitor Kunitz
MSLYGMMRTGVSGMNAQANRLSTVADNIANASTVGYKRAETQFSSLVLPS
TAGQYNSGSVLTDVRYGISDQGGIRSTSSTTDLAIDGNGYFVVQGPGGST
YLTRAGSFVPDKNGDLVNSAGYYLLGAGADEAAGGLTVAGLNVVNVNAAA
LPAEGSTAGDFTVNLPSTDQAPAAGGYNHKTSLISYNDKGEKITLDVYFT
KTGADEWNVSVKNAADGVEIGTTVLNFDPTTGDLVSGGNVAVNLGAYGGQ
TLNLNLGGSTQRAGDYTISQAVINGQAPSSIKGVDVGNDGAVVAVYENGT
QKVLYRIPLANVASPDRMTVVSGNIFLPSAESGDVRLGFPQGDGMGKIMS
GTLEESNADIAQELTDMIEAQRSYTANSKVFQTGFELMDVLVNLKR
>BAB2_1106 Flagellin, C-terminal:Flagellin, N-terminal
MASILTNSSALTALQTLASTNKSLESTQNRISTGLRISEASDNASYWSIA
TSMKSDNKANSAVQDALGLGAGKVDTAYSAINKIRESVDDIKTKLVSAMG
ASTEDKGKIETEIKSIVANINSALSNANYAGSNLLNGPTTDLNVVASYNR
SGNAVTVDKITVKATDTDAKTMVKDIVDAGFFTSASDDTAIGTALNTVET
ALASLATGAATLGAAKSQIDSQKSFLSGLQDSIEKGVGTLVDADMNKESA
RLSALQVQQQLGVQALSIANSSNQSILSLFRG
>BAB2_1093 ATP/GTP-binding site motif A (P-loop):Flagellar hook capping protein
MTTTSPVGSNTTNSASTASNSTSAANKASVDYDSFLKLLVTQMQNQDPTQ
PMDPTQYVSQLATFSNVEQSVQMNSKLETLIANTSLTQAEGWIGRTLTNA
DGSISGVVKSVTIQSSGMLAELEDGKTLTIGEGVRIS
>BAB1_1726 OmpA/MotB domain
MALARNRRTQRHIDYWPGFVDALTTLLLAIMFLLTVFVLAQFLLSREVNN
KDSVLARLNSQIQELTQLLSLERSNSQDMQDTIANLQASLSTVESERSRL
QSLLNEGSGAGAAAEKRAGELAQSLDAEKQVSARALNQVELLNQQIAALR
RQIAALEDALNASESRDRESNAKIADLGRRLNVALAQRVQELNRYRSDFF
GRLREILSDKENIRIVGDRFVFQSEVLFPTGSAEINPKGQVEMKKLADAI
IQLNREIPDDINWVLRVDGHTDNVPLAGTGRFRDNWELSSARATAVVKFL
IANGVPANRLVAAGFGEYQPLDTANTADARARNRRIELKLTER
>BAB2_1088 Bacterial export protein, family 1:Flagellar biosynthesis protein FliR
MPVTQLPLNEIILAAVLAFCRIGACLMLMPGISSARIPLQVCLFIALACS
FAVLPLVLQRIVTAVDAGQPWTLFRLMVGEMFIGALIGILAHIYFWALQF
MANMMAMAVGYSGSPADSITENEPQATLATIVTFSALFLFFVTDMHLEIF
RALLNSYVAIPVDGRFRPDAAMIDFTDALSAAFLATLRIAAPFIVFAILV
NFAIGLVNKLTPAIPVYFISMPFVLGGGLLVVYFILPELLRFFTHETATQ
LRELF
>BAB2_1103 OmpA/MotB domain
MNIEPETKREIIIVRRGGHDDHEAHHGGVWKIAYADFMTAMMAFFLVLWL
INAANEETKAAVASYFNPVKLMDRHSSPKGVQNVDQRDGKVRFESDQQVE
SSTKVVNDTTVRPASDQEERQLFREPYAMLAELAHETGVLQNQSAKGDGG
TAQSGSASGADGGEAYRDPFSPDYWSSKAVGDLTPPAPQTVPQTAPLPQA
QPKKAETQEELIADLKKAATGEPAPNAGKAAKPEPMPDVTVVPVEGGVMS
QLTDKVDYGMFTIGSAKPDARVVQMLERIAQVIARQPGEVIISGHTDARP
FKSATYDNRRLSSARAQMAYYMLVRGGLDEKRVLRVEGYADRHPKNPNDP
NAAENRRIDIFIKSKP
>BAB2_1097 flagellar hook-associated protein FlgK, putative KO: K02396 flagellar hook-associated protein 1 FlgK
MSLSSALLTAKSSLAATSKQTSVVSRNISGAKDADYSRRTASLVSGPYGS
LYVGISRSADEAMFNRYIQSNSAASASSTLADGLDRLSALYSADNYSGSP
SGLIGDLRDALQTYVASPSNSALGDSVVSVAQSLANALNDGTRQVQSLRN
DADREIADSVANINDLLAKFEKANQDVVGGTRMGRDVSDYLDQRDALLKQ
LLGEIGITTMMRGDNDMVIFAENGVTLFETTARKVTFEQSAVLTPGVAGK
AVTVDGVPLSHDTFDQPFGTGRLSGLLQLRDQIAPQYQMQLDEIARGLVT
VFAESDQTGSSPDQTGLFSWSGSPAIPGAGLSAGIAGTIEVSVPFIASEG
GSALLLRDGGANGANYKYNVQGAAGFSDRLRALNEAFSEPMVFDAAAGIS
SSSSLIGYSASSLGWLEGKRQKANSEFTYNGTVASQADFALSNATGVDID
TEMALLLDLEHSYQASSWVLTTVSAMLDDLLNAV
>BAB2_0152 Flageller protein FlgA
MDRVKAIFQTARLALAGGFLLAAMAGAGAADRIAFVVPSATVYPGQIVSD
TALLEKQFFINAPAATQYVLSLDQAVGKVARKTLLPGKPILVSALGEPSL
VTRGIPAPLVFTAGTLTITAMGTPLESGVAGDFIKVRNVDSGIIVSGTVL
ANGRIQVGMQ
>BAB1_1885 
MAKSGTPRHSKPARNPVTINLDPSEVRRVDEPAAAKATPAAEPVGGFSGK
AEAKPAAQAAPASSTGPDKAPFTAGVKPEAESPRETANAAPSAATPPADG
RSGGGASHLLAGVAGGVIALGGMFALQWGNVIPSPGARVTAGQLAHMEQQ
IADLRSNPAPAPLDDAGKAEFARLQKNVEAAEIKAEAVAGTLSELQKQIE
ALPTTSENGTAAGDIASLSERLDALETKLSETRSQADEASAGVSGNSGTI
SSLESKLTSLQEKMSETARQPDAAVLIAANALKTAIDRGGSFKAELDTYV
SVAPQDASVEGLRAYADKGVPTIADLNAWFGAVANRIVATENKLPADASL
WDQLLASARGLVSVRPVAGNVSGTGVGPTTARMEAALQAGDLDRAIGEWE
QLPADAKAVSEEFASQMKARRDADALVQRLVADSLKPKAPVTGASDNTTG
EAPASSGQ
>BAB2_0120 Type III secretion exporter:Flagellar biosynthetic protein FlhB
MADDADKESKTEEATEQKIRDAQDKGNMPFSREAPILAGIASFLVIAVFV
AAPAATRLAVFLRELIDRPEDWLLNSAEDATRLFSVLALAVGAALVPVFI
IIPLAGIAASAFQNAPRFVGERIRPQASRISPLKGWQRIFGRAGQVEFLK
SLAKLLAASVIVFLVFFKGDSLFTDAVATDPGALPEFLRKNVVRLLVANV
LAIAAIAGFDLAWSRIHWRQELRMTRQEVKDELKQSEGDPLVKSRLRSLG
RDRARRRMINAVPTATLIVANPTHFSVALRYKPNEDAAPVVVAKGQDLIA
LKIREIAASHSIPVFEDVQLARALYKQVNVDQMIAPEFYKAVAELIRIIN
TRRAIS
>BAB2_1096 flagellar hook-associated protein FlgL, putative KO: K02397 flagellar hook-associated protein 3 FlgL
MKAQSISTYGATSALRALVAKNKAEMVKAQQEATTGTVFDVGLSLGSRTG
QTVSLRKEYDRLSVLTDMNKLVQQRMTATQTAAGKIIENTQNFLGDLAGA
NNSGETAKTVAKSARSMLDSVTGLLNTSFNGEYIFAGVNTDVKPISDYAD
GSTAQNAVRQAFQDHFGFAMDDPQVANISGDEMKAFLEGDFAEQFNDANW
AANWSDASDTRIKSRISPTETADTSISANADGFRKTVMSAVMVTEFADIG
LNASAFDALTTQALQITTQAVTETTSEQTTLGLAQSRTEAATTRIAAQQK
ILNQSVLNLEEVDPYDAATRVNALKTQIETSYSLTVQLQNMSLLNYLR
>BAB2_0126 Flagellar motor protein MotA
MGIIVGLVITLGCMLGGFIAMGGHVSVLIQPWEFIIILGAALGTFFVANP
FSLVKDTGRACMEAFTDAVPKQRDYLDVLGVLYSLMRELRAKSRNEVEVH
IDNPKESPIFLAYPSVLKKEDLTNFICDYCRLIIVGNVRSYEIEALMDEE
IRTIARDKLKPYQAMITISEALPALGIVAAVLSVIKAMGALDQSPEVLGH
LIGAALVGTFAGIFFSYGVIGPIANKIKSTREKNNRLYIVVKQTLLAYMN
GSLPQIAVEYGRKTISAYERPTIDVVEQETMASVPTQQAA
>BAB2_0122 Flagellar motor switch FliN protein:Surface presentation of antigens (SPOA) protein
MQQELNEAIEELREEKPRSAQKSASKPNLDLIMGIPVDVQVVLGGTTMPV
SSLMKLGRGAVITLDKQIGDPVDIVVNGRVIARGEVIVLEDDSSRFGVSL
TEIIGK
>BAB2_0148 flgB, Flagellar basal-body rod protein FlgB
MSSIHLFDLAARQAQWLSVRQATVAGNVANADTPDFRARDVQPFADVLDK
TQLTMTATSPLHLEAEADGIAATRLRPDDVTEQTHSGNTVDVEQEMMKAG
EIAREYSLNTSIVKAFHRMMLSVAKG
>BAB2_0128 flgF, Flagellar basal body rod protein
MQNNSIYVGLSSLITLERRMDAIAHNVANASTVGFRGEGTKFDTIVSDKA
SDDVSFATAGKSYIRTEAGPLIKTDNPLDVAVKGDAWMSFSTPQGQVYSR
DGRMKMLSTGDPVSVTGNAILDVGGAPIVLNPGGGAPRISSDGAIYQNGV
QVGAIGLYTIPADADLAYAGTSGVIPSKPAQPVVDDNSVGVVQGMIEGSN
VDAMTEMTRLISISRAFEQVNNLLSQQEATVSEAIKTLGSKNG
>BAB2_0151 flgG, Flagellar basal body rod protein
MKALTIAATGMNAQQLNLEVIANNIANINTTGFKRARAEFTDLLYQSERT
AGVPNQANQAIVPEGALVGLGVQTAAVRNLHIQGSFNQTGNPYDVALTGR
GWFQIQSPTGETLYTRAGAFNKNADGQLVTLDGNPVEPAITIPPDAIEVT
ITDTGQVFAKLQDQINQVDLGQLTLANFTNEAGLEPLGGNLYRETEASGG
PLVGVPGDPGYGSIKQGYLEASNVDPVKEITDLITAQRAYEMNSKVIQAA
DEMAATVSKNLR
>BAB2_0156 flgH, Flagellar L-ring protein
MKNSMNKAILAVAMVLLLAGCATKPEEIGRAPDLSPVAAHLGMQNNPQFN
GYPARPGKASYSLWDQRSTNFFKDPRAATPGDVLTVIISINDRANLDNKT
DRERVSKGIYGGGGSFATSSITGAAAGGDMDASVNTHSDSKSKGKGTIER
SEDIRLQIAAIVTDTLPNGNLIIRGSQEVRVNNELRVLNVAGVVRPRDIS
GNNTISYDKIAEARISYGGRGRLSEIQQPPYGQQILDQFSPF
>BAB2_0150 fliE, Flagellar hook-basal body complex protein FliE
MYDSIMSVSARNALSRLSETVAEKGVGSASAPQAVPAAPGASFGEVLSQM
TGSVSQKLQAAEATSIQGIKGDAPVRDVVSSVMEAEQSLQTAIAIRDKIV
QAYLEISRMPI
>BAB2_1105 fliF, Flagellar FliF M-ring protein:Type III secretion system outer membrane K protein:Secretory protein YscJ/FliF
MAVVWMQQNFQQLIEQLKGTLGKLGARKLIALGLVGAALMGAILYTSIYL
GRPSYETLYVGLSRDDVNRMGLALGEAGIPFDVKSDGSSILVPIGKAENA
RMYLAEKGLPTSNNAGYELFDNMGSLGLTSFMQEITRVRALEGEIARTIQ
AIRGVKAARVHIVLAEKGSFRRGDQKPSASVVIRAEGGFSAESAQSIRQL
VAAAVPSLDASSVTVLDTNGHLLASAGEGANGAALMTASLEQQVASHVDD
SIRKALAPYLGLGHFQTSVQAALDTDRRQTKETTYDPESRVERSVRVVRE
SGDSRNNRNDNATGVEQNIPQEQIQNRNGESSTEKTDRREELTNYEVNSK
TVSTVSDGYSIKRLSIAVVIDQARLLQTAGTTPPPANFVDQQITKIRDLV
ATAAGLNTNRGDVINVTAVNFLDPAGADMEPVSAPWTDTLLRQSGSYANA
LAILAAVGLLIWFGLRPLLRDQNVKPAGTEVAIREAGEVATPNFIGGAES
VGEGVQAVIGGPAAYADQMKTSLSDLRQRMRMPAKLRLEQMIEMDEERVA
AVLKQWIHETASGREADPAKASAMPELKAA
>BAB2_0129 fliI, H+-transporting two-sector ATPase, alpha/beta subunit, central region:Disease resistance protein:ATP/GTP-binding site motif A...
MTPDLPLTRLAAFVRQQTIAPEPLTGIGGTVSDVSRSSIAVRGLSRDARL
GDTVAIRAGEGAPSLAEIIRVADLQVLVKPFDDRIMPSLGAAVFEEGPLR
IRPAPEWRGRVINALGNAIDGKGALKPGTRPMAAESLAPAALRRARVDRG
LRTGVNVIDIFTPLCFGQRIGIFAGSGVGKSTLLAMMTRAADFDTVVLAL
TGERGREVREMLEETMAGHLGKTITVVATGDESPMMRRLAPNTATAIAEY
FRDLGQNVLLIVDSVTRFAHAAREVAIAAEEPPVARGYPPSVFSQLPRLL
ERAGPGSAEAGGSITGIYSVLVDGDDHNDPVSDTIRGTLDGHIVLDRAIA
AQGRFPAVDIPASVSRLAKHNWTPEQRKLVMQLRSMVARFEETRDLRAIG
AYQKSHDGLLDQAVDFVPRIYEALQQSPETGLSDDPYNDLAAALRGDRQA
QNA
>BAB2_0158 fliP, Flagellar transport protein FliP:Type III secretion system inner membrane P protein
MKHSLGLGVILTLALTVSAQAQQALPLDKLLPAGSGAASGQIVQLFGLLT
VLSIAPGLLIMVTSFTRFAIAFSLLRSGLGLQTAPASMVMISLALFMTFY
VMAPAFDRAWNNGVQPLMRNEITQEAAFGEISQPFREFMMAQVRDKDLCL
FEDLADPSFRTSDDGIVDFRVLVPAFMISELRRGFEIGFLIVLPFLVIDL
VVATLTMSMGMMMLPPTVISLPFKILFFVLIDGWNILVGSLIRSFS
>BAB2_1092 fliQ, Bacterial export protein FliQ, family 3:Flagellar biosynthesis protein FliQ
MNEADALDIVNSAIWTVLTASGPAVLAAMLAGIGIALFQALTQIQEMTLT
FVPKIIVIFVVLALTAPFVGAQINAFTLLAYSRIEKGF