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# Streptococcus pyogenes phage 6180.4

>M28_Spy1336 R28 protein
MFRRSKNNSYDTSQTKQRFSIKKFKFGAASVLIGLSFLGGVTQGNLNIFE
ESIVAASTIPGSAATLNTSITKNIQNGNAYIDLYDVKNGLIDPQNLIVLN
PSSYSANYYIKQGAKYYSNPSEITTTGSATITFNILDETGNPHKKADGQI
DIVSVNLTIYDSTALRNRIDEVINNANDPKWSDGSRDEVLTGLEKIKKDI
DNNPKTQIDIDNKINEVNEIEKLLVVSLPDKIKYSPEAKHRTVEQHAELD
AKDSIANTDELPSNSTYNWKNGHKPDTSTSGEKDGIVEVHYPDGTVDDVN
VKVTVTSKKTDNTAPTLTVTPEQQTVKVDEDITFTVTVEDENEVELGLDD
LKAKYENDIIGARVKIKYLTKEPNKKVMEVTIMKATLADKGAITFTAKDK
AGNQAEPKTVTINVLPLKDSNEPKGKDQTVKVGETPKAEDSIGNLSDLPK
GTTVAFEAPVDTATPGDKPAKVVVTYPDGSKDTVDVTVKVVDPRTDADKN
DPAGKDQTVKVGETPKAEDSIGNLSDLPKGTTVAFEAPVDTATPGDKPAK
VVVTYPDGSKDTVDVTVKVVDPRTDADKNDPAGKDQTVKVGETPKAEDSI
GNLSDLPKGTTVAFEAPVDTATPGDKPAKVVVTYPDGSKDTVDVTVKVVD
PRTDADKNDPAGKDQTVKVGETPKAEDSIGNLSDLPKGTTVAFEAPVDTA
TPGDKPAKVVVTYPDGSKDTVDVTVKVVDPRTDADKNDPAGKDQTVKVGE
TPKAEDSIGNLSDLPKGTTVAFEAPVDTATPGDKPAKVVVTYPDGSKDTV
DVTVKVVDPRTDADKNDPAGKDQTVKVGETPKAEDSIGNLSDLPKGTTVA
FEAPVDTATPGDKPAKVVVTYPDGSKDTVDVTVKVVDPRTDADKNDPAGK
DQTVKVGETPKAEDSIGNLSDLPKGTTVAFEAPVDTATPGDKPAKVVVTY
PDGSKDTVDVTVKVVDPRTDADKNDPAGKDQTVKVGETPKAEDSIGNLSD
LPKGTTVAFEAPVDTATPGDKPAKVVVTYPDGSKDTVDVTVKVVDPRTDA
DKNDPAGKDQTVKVGETPKAEDSIGNLSDLPKGTTVAFEAPVDTATPGDK
PAKVVVTYPDGSKDTVDVTVKVVDPRTDADKNDPAGKDQTVKVGETPKAE
DSIGNLSDLPKGTTVAFEAPVDTATPGDKPAKVVVTYPDGSKDTVDVTVK
VVDPRTDADKNDPAGKDQTVKVGETPKAEDSIGNLSDLPKGTTVAFEAPV
DTATPGDKPAKVVVTYPDGSKDTVDVTVKVVDPRTDADKNDPAGKDQTVK
VGETPKAEDSIGNLSDLPKGTTVAFEAPVDTATPGDKPAKVVVTYPDGSK
DTVDVTVKVVDPRTDADKNDPAGKDQTVKVGETPKAEDSIGNLSDLPKGT
TVAFETPVDTATPGDKPAKVVVTYPDGSKDTVDVTVKVVDPRTDADKNDP
AGKNQQVKGKGNKLPATGENATPFFNVAALTIISSVGLLSVSKKKED
>M28_Spy1199 prepilin peptidase family
MIAFFSICSGILLTHLFYCLLLYFPDNGQEQLSKQTVIVCDQLTFAKRVF
RQLQNHFITSQKIFFSLEISLIIILWASMVHWVSASYCYLLLFSLLFSLF
DWRSQEYPFILWLFSFVSLLLFYSINYLSLILLLLGLLAHLRPFSIGAGD
FFYLASLALVLDLTSLIWLIQLASLAGITACLLLGIKRIPFIPYLSFGLF
WIVLLEHF
>M28_Spy0992 phage protein
MNKRIKKKRKLETAVVMLVAENAIQAKALRNQNKQIAELRAIIQQNVQAI
NREFVTAKNTILDNQLAIKLIGDDVGHIKQNYKRKWRK
>M28_Spy1226 phage-associated cell wall hydrolase
MTFLDDIKQGCLDGWTKYKILPSLTAAQAILESGWGKHAPHNALFGIKAD
ASWTGKSFDTKTQEEYQPGIVTDIVDRFRAYDSWTDSIIDHGKFLNDNPR
YKAVIGETDYKKACYAIKAAGYATASSYVELLIQLIEENDLQSWDREALK
NNKEETMTTANEIVQYCVNLANSGMGVDKDGAHGTQCCDLPCFVAKNWFG
VDLWGNAIDLLDSASAQGWEVHRMPTEANPKAGATFVQSVPYHQFGHTGI
VIEDSDGYTMRTVEQNIDGNADALYVGAPARFNTRDFTGVVGWFYPPYQG
DTVTQPVSTEPQTSDTIVETAKTGTFTLDVAEINIRRWPSLASEVVGIYK
QGDTVSFDSEGYANGYYWISYVGGLGMRDYLAIGQTDKDGNRISIWGKLN
>M28_Spy1299 hypothetical cytosolic protein
MAKQKNRKKALKLEMKRNGLLKKAGQVFDKAVESVETAVDKTISAGKNLV
EKGSQTVENLTASKERLTLDEFAGQPVVAGIRSDLVETLYAEGIHSAQAF
KEWTEKDLLALKGIGPATVKKLVENGASFKK
>M28_Spy0088 hypothetical protein
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEK
LNLALMAVQTRTKEITLNGCHITILRTDRYISIHDDEGEVMKIE
>M28_Spy1490 N-acetylmuramoyl-L-alanine amidase
MRKRLKFPYFLTLLACFLLLIVCPLLSSQRIASADKEVRVNYSQKQFITK
MGKEVKPLAKYYGIRPSILIAQILLETHDGKTLLASKYHNLFSKKATPGQ
AAITLKSPKQTNQNVRYAIYKDDASAIRDYLRMLRQGKEVDKRLYRNLAT
EKGYKAPAKSLQKYLHYTDKTYARRLIQVIESNDLTNYD
>M28_Spy0338 hypothetical protein
MKWSDFMKTKSKRFLNLATLCLALLGTTLLMTRPVKAEVSEIGHDHVTIS
SNGQTDEGAAYGRGHDDGSKFGYEAGLQSSWNESEPPSSDKIPEPSVNPY
ESSNEQDREDYKEGFRDGYPGGYVAGWRKTHPIEATLQYLWYTVSSWFES
LFNNSK
>M28_Spy0087 ComG operon protein 4
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHF
EHLYRHQQKLAILQQKQRVLDISSTKIVTEGNSLTVPKSITVNHPYRLVI
DQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP
>M28_Spy0852 hypothetical protein
MLKKCLTIVKHRLKESRSTMTKKNHGVFWGLLLGSAAASIAYLSLSSSKK
DQLLKDSAKKIDDLNAYLQDKSKQVLDAVSEKVQESKDAVEVYGGIAAET
VEEKWQDTKDAVEVYGGIATETVEESLGQVKEKVEGIGEATSQTIQSKME
KLTSDKTDADDEK
>M28_Spy0953 cfa, cAMP factor
MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTILMNNNQANLQRDA
LVQKLDEGHQQLEAIKHEAKGTDIEATVNKAIDAVDHMKSSIRFNTETIY
DFSSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIID
PFASVDAIKAQVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTR
LERDKKVLGIKSFDVYNRLNKAITHAVGVQLNPTTTVQQVDDEVIAVQNA
LETALKS
>M28_Spy0084 comYA, ComG operon protein 1
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDR
MAPLISHFKFVAGMIVGEKRRCQVGSCDYKLSKDKQLSLRLSSVGDYRGQ
ESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMY
QLISSYHQEAQVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHR
PDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGVYVRLLELGVT
KAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGH
LNPKQAKLEKII
>M28_Spy0085 comYB, ComG operon protein 2
MTLLKTNLNIIPHRTGINKLISFLRQDISIPSKLSLKKLSSKHQHKFIQL
LANLLSTGFSFAEVIAFLKRSQLLQLDYVLKMEESLLKGQDLADMLSGLG
FSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRRKTVEVITYPLILL
LFLFVMMLGLRRYLVPQLETQNQITYFLNHFPAFFIGFCSGLILLFGMVW
LRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWGTLIGQGLDLMTI
LDIMAIEKSSLMKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYG
EIKSKLGAELEIYAQESWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAA
ILLPIYQNMGGIF
>M28_Spy0753 lepA, GTP-binding protein
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLL
DSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRS
LAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPE
RVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPL
QALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFT
PKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQM
NPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCG
FLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFP
DPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVN
VIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGD
KVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARS
DIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLS
VLSMDDDAKK
>M28_Spy0234 mecA, negative regulator of genetic competence
MRMEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDEL
DLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEINKDINLEDLAEFGDMSQM
TPEDFFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPS
TNHESEPLDYVHYVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTI
LLDVQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQLMLDGAVEQLQ
KIELG
>M28_Spy0644 mur1.1, autolysin
MKVKKRRRRAKSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYADHETLT
FVRKISHAAQSVAQKKQLYSSVMMAQAILESNNGKSQLSQKPYYNFFGIK
GSYKERSVIFPTLEDDGQGNLYQIDAAFRSYGSLTACFLDYARVLNDPLY
DKTHKKFWSHYQDATATLTGTYATDTTYNTKLNELIEWYQLTNFDGLMK
>M28_Spy0645 mur1.2, autolysin
MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSSTRHFID
EIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAY
NGSSVTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGA
RKSNTLSYQDATAALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQE
TGLATSGYVWNEYRRNYTDAETLAVDEAWAKRMTY
>M28_Spy1737 secE, protein translocase subunit
MGFISGTFKVLKDTTWPNRKQRWKDFISVLEYTAFFTVIIYIFDQLLAKS
VLALINLF