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# Streptococcus pyogenes MGAS10394, MGAS10394

>M6_Spy0988 Phage-associated cell wall hydrolase
MAFLDNIKQGCLDGWVKYKILPSLTAAQAILESGWGKHAPHNALFGIKAD
SSWTGKSFDTKTQEEYQPGVVTDIVDRFRAYGSWDESILDHGKFLNDNPR
YKAVVGETDYKKACHAIKEAGYATASGYAELLIQIIKENGLQFWDAEVLK
SNKEETMTTANEIVKYCVDLANSGMGVDKDGAYGT
>M6_Spy1281 Prepilin peptidase family
MIAFFSICSGILLTHLFYCLLLYFPDNGQEQLSKQTIIVCDQLTFAKRVF
RQFQNHFITSQKIFFSLEISLIIILWASMVHWVSASYCYLLLFSLLFSLF
DWRSQEYPFILWLFSFVSLLLFYSINYLSLILLLLGLLAHLRPFSIGAGD
FFYLASLALVLDLTSLIWLIQLASLAGITACLLLGIKRIPFIPYLSFGLF
WIVLLEHF
>M6_Spy0261 Surface exclusion protein
MEKGERMDLEQTKPNQVKQKIALTSTIALLSASVGVSHQVKADDRASGET
KASNTHDDSLPKPETIQEAKATIDAVEKTLSQQKAELTELATALTKTTAE
INHLKEQQDNEQKALTSAQEIYTNTLASSEETLLAQGAEHQRELTATETE
LHNAQVDQHSKETALSEQKASISAETTRAQDLVEQVKTSEQNIAKLNAMI
SNPDAITKAAQTANDNTKALSSELEKAKADLENQKAKVKKQLTEELAAQK
AALAEKEAELSRLKSSAPSTQDSIVGNNTMKAPQGYPLEELKKLEASGYI
GSASYNNYYKEHADQIIAKASPGNQLNQYQDIPADRNRFVDPDNLTPEVQ
NELAQFAAHMINSVRRQLGLPPVTVTAGSQEFARLLSTSYKKTHGNTRPS
FVYGQPGVSGHYGVGPHDKTIIEDSAGASGLIRNDDNMYENIGAFNDVHT
VNGIKRGIYDSIKYMLFTDHLHGNTYGHAINFLRVDKRNPNAPVYLGFST
SNVGSLNEHFVMFPESNIANHQRFNKTPIKAVGSTKDYAQRVGTVSDTIA
AIKGKVSSLENRLSAIHQEADIMAAQAKVSQLEGKLASTLKQSDSLNLQV
RQLNDTKGSLRTELLAAKAKQAQLEATRDQSLAKLASLKAALHQTEALAE
QAAARVTALVAKKAHLQYLRDFKLNPNRLQVIRERIDNTKQDLAKTTSSL
LNAQEALAALQAKQSSLEATIATTEHQLTLLKTLANEKEYRHLDEDIATV
PDLQVAPPLTGVKPLSYSKIDTTPLVQEMVKETKQLLEASARLAAENTSL
VAEALVGQTSEMVASNAIVSKITSSITQPSSKTSYGSGSSTTSNLISDVD
ESTQRALKAGVVMLAAVGLTGFRFRKESR
>M6_Spy0874 Hypothetical protein
MTKKNHGVFWGLLLGSAAASITYLSLSSSKKDQLLKDSAKKIDDLNAYLQ
DKSKQVLDAVSEKVQESKDAVEVYSGIAAETVEEKWQDTKDAVEVYGGIA
TETVEESLGQVKEKVEGIGEATSQTIQSKMEKLTSDKTDADDEK
>M6_Spy0138 ComG operon protein 5
MIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMT
LNGCHITILRTDTYISIHDDEGEVMKIE
>M6_Spy0683 Autolysin
MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSSTRHFID
EIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAY
NGSSVTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGA
RKSNTLSYQDATAALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQE
TGLATSGYVWNEYRRNYTDAETLAVDEAWAKRMTY
>M6_Spy0682 Autolysin
MKVKKRRRRAKSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYADHETLT
FVRKISHAAQSVAQKKQLYSSVMMAQAILESNNGKSQLSQKPYYNFFGIK
GSYKERSVIFPTLEDDGQGNLYQIDAAFRSYGSLTACFLDYARVLNDPLY
DKTHKKFWSHYQDATATLTGTYATDTTYHTKLNELIEWYQLTNFDGLMK
>M6_Spy0135 ComG operon protein 2
MISFLRQDISIPSKLSLKKLSSKHQHKFIQLLANLLSTGFSFAEVIAFLK
RSQLLQLDYVLKMEESLLKGQGLADMLSGLGFSDAILTQISLADRHGNIE
TTLVAIQHYLNQMARIRRKTVEVITYPLILLLFLFVMMLGLRRYLVPQLE
TQNQITYFLNHFPAFFIGFCSGLILLFGMVWLRWRSQSRLKLYSRLSRYP
FLGRLLKQYLTSYYAREWGTLIGQGLDLMTILDIMAIEKSSLMKELAEDI
RMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELEIYAQESWE
QFFSQLYQVTQLIQPAIFLVVAVTIVMIYAAILLPIYQNMGGIF
>M6_Spy1342 N-acetylmuramoyl-L-alanine amidase
MAFLDKIKSAVIAEWHTHKILPSLTAAQAILESGWGKYAPHNALFGIKAD
SSWTGKSFNTKTQEEYQPGIVTDIVDRFRAYDSWEDSIADHGQFLADNPR
YKAVIGEADYKKACHAIKDAGYATASGYADLLIQLIEENNLQEWDAEAIK
NKEEQMISSQCREVIEFFINLANAGVGVDKDSFAGWQCADVPCYAAKHWF
GVDLWGNAIDLLDSAAAVGWEVHRMPTDANPRTGAFFVQSVPCHQFGHTG
IVIEDSDGYTMRTVEQNIDGNPDALYVGAPARFNTRDFTGVLGWFYPPYQ
GDIVTQPVSTEPQNSDTIVETPKTGTFTLDVAEINIRRWPSLASEVVGSY
KQGDTVSFDSEGYANGYYWISYVGGLGMRNYLAIGQTDKDGNRISIWGKL
N
>M6_Spy1202 Phage infection protein
MSRDPTYTINEHDLSFADGRFYVTFKADKSSETVRLNSSCLGNTIIKKLQ
VEDDNTMHDFVKPKVTTQQAFGLAQQVKELDLQLKDPKSDLWGKIKFNNK
AMLVEYANKEMSSAIAQSAEQILLQVKSIDDERYSKFEQTLNGIKQTVKS
ESVESARTQLASMFDSRISGLDGKYSRLSQTIDSLSSRLDDGVGNYSTLS
QKVSGIDLRVSNAANDVSRLSQTAQGLQSQITNANQNYSSLSQTVQGLQT
TVRDNQSNATSRINQLSDLISTKVSKGDVETTIAQSYDKIAFAIRDKLPA
SKMSGSEIISAINLDRSGVKITGKNITLDGNSYISNAVIKDAHIANMDAG
KINTGYLNANRIATEAITGEKIKMDYAFFNKLTANEGYFRTLFAKDIFAT
SVQSVTLSASKITGGVLAATNGASQWDLNNANMTFNRDATINFNSKNNAL
VRKDGTHTAFVHFSNATPKGYRGSALYASIGITSSGDGIDSASSGRFCGV
RFFRYAEGLQHTAKVDQAEIYGDDIVFSDDFNIDRGFKMRPSLMPKMVDL
NKMYQAILALGRCWLHANNTAWSWNFDTRSAIIAEYNAHINNL
>M6_Spy1170 Hypothetical Protein
MFFLKAKDVSIVDGPIAEAVIHVQKITSEQIEFHFGWITSVSGIGGNEYF
GGMTYLVATIIYIILNDSSLKNRMIRISLDMQSEAREVAINRKIDVYHKF
FKTPKNISDVSEFSFHRVATFSPENRKHDLEYFKGIIEEKEKSILSVLDS
YR
>M6_Spy0137 ComG operon protein 4
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHF
EHLYRHQQKLAILQQKQRVLDISSTKIVTEGNNLTVPKSITVNHPYRLVI
DQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP
>M6_Spy1751 Protein translocase subunit secE
MGFISGTFKVLKDTTWPNRKQRWKDFISVLEYTAFFTVIIYIFDQLLAKS
VLALINLF
>M6_Spy0065 Phage-associated cell wall hydrolase
MTFLDKIKQGCLDGWTKYKILPSLTAAQAILESGWGKHAPHNALFGIKAD
ASWTGKSFDTKTQEEYQPGIVTDIVDRFRAYDSWTDSIIDHGKFLNDNPR
YKAVIGETDYKKACYAIKAAGYATASSYVELLIQLIEENDLQSWDREALK
NNKEETMTTANEIVQYCVNLANSGMGVDKDGAHGTQCCDLPCFVAKNWFG
VDLWGNAIDLLDSASAQGWEVHRMPTEANPKAGATFVQSVPYHQFGHTGI
VIEDSDGYTMRTVEQNIDGNADALYVGAPARFNTRDFTGVVGWFYPPYQG
DTVTQPVSTEPQTSDTIVETAKTGTFTLDVAEINIRRWPSLASEVVGIYK
QGDTVSFDSEGYANGYYWISYVGGLGMRDYLAIGQTDKDGNRISIWGKLN
>M6_Spy1219 unknown phage protein
MNKRIKKKRKLETAIMLLIAENALQAEAIKNQNKEIMELKSIVQRNALAT
NEELATVKAATLDNQSVIKAIGDTVDYIKKNYKRKWGK
>M6_Spy0271 Negative regulator of genetic competence
MRMEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDEL
DLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEINKDINLEDLAEFGDMSQM
TPEDFFKSLEQSMREKGDVKAHEKLEQIEEIMEDVVEATLANQSEAADPS
TNHESEPLDYVHYVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTI
LLDVQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQLMLDGAVEQLQ
KIELG
>M6_Spy1495 N-acetylmuramoyl-L-alanine amidase
MRKRLKFPYFLTLLACFLLLIVCPLMSSQRIASADKEVRVNYSQKQFITK
MGKEVKPLAKYYGIRPSILIAQILLETHDGKTLLASKYHNLFSKKATPGQ
AAITLKSPKQTNQNVRYAIYKDDASAIRDYLRMLRQGKEVDKRLYRNLAT
EKGYKAPAKSLQKYLHYTDKTYARRLIQVIESNDLTNYD
>M6_Spy0046 unknown phage protein
MNKRIKKKRKLETAVVMLVAENAMQAEAIKNQNKQIMELKSIVQRNALAT
NEELAAVKAATLDNQSVIKAIGDTVDYIKKNYKRKWGK
>M6_Spy1361 unknown phage protein
MNKRIKKKRKLETAVVMLVAENAMQVEAIKNQNKQIMELKSIVQRNALAT
NEELATVKAATLDNQSVIKAIGDTVDYIKKNYKRKWGK
>M6_Spy1718 C5A peptidase precursor
MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPATEQAVETPQP
TAVSEEAPSSKETKTPQTPDDAEETVADKANDLAPQAPAKTTDTPATSKA
TIRDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARY
QSKEDLEKAKKEHGITYGEWVNDKIAYYHDYSKDGKTAVDQEHGTHVSGI
LSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLADYARNYAQAIRDAV
NLGAKVINMSFGNAALAYANLPDETKKAFDYAKSKGVSIVTSAGNDSSFG
GKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETATVKTADQQD
KEMPVLSTNRFEPNKAYDYAYANRGMKEDDFKDVKGKIALIERGDIDFKD
KIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKENP
QKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSV
ANNKYAKLSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLM
SSATALYDEDEKAYFSPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLN
NVSDTFEVTVTVHNKSDKPQELYYQATVQTDKVDGKHFALAPKALYETSW
QKITIPANSSKQVTVPIDASRFSKDLLAQMKNGYFLEGFVRFKQDLTKEE
LMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSDAKDQLDGDGLQ
FYALKNNFTALTTESNPWMIIKAVKEGVENIEDIESSEITETIFAGTFAK
QDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVL
DKEGNVVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVAN
GTYTYRVRYTPISSGAKEQHTDFDVIVDNTTPEVATSATFSTEDRRLTLA
SKPKTSQPVYRERIAYTYMDEDLPTTEYISPNEDGTFTLPEEAETMEGGT
VPLKMSDFTYVVEDMAGNITYTPVTKLLEGHSNKPEQDGSDQVPDKKPET
KPEQDGSGQAPDKKPETKPEQDGSGQAPDKKPEAKPEQDGSGQTPDKKPE
TKPEKDSSGQTPGKTPQKGQPSRTLEKRSSKRALATKASARDQLPTTNDK
DTNRLHLLKLVMTTFFFGLVAHIFKTKRQKETKK
>M6_Spy0134 ComG operon protein 1
MVQVLAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDR
MAPLISHFKFVAGMIVGEKRRCQVGSCDYKLSKDKQLSLRLSSVGDYRGQ
ESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMY
QLISNYHQEAQVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHR
PDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGVYARLLELGVT
KAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGH
LNPKQAKLEKII