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# Tropheryma whipplei str. Twist, twist

>TWT312 glycosyltransferase
MVHGKSLRVLIGTETFPPEVNGAAKFSGRLASCLIERGHIVRVVAPSRTR
GRGGEYLEEIEGNAVLVYRLPSVKWPGHSWFRFASPLFVSRFCSKIIDDF
QPDVIHYQSHFMIGLSLSKKGRARGVRLVGTNHFMPDNVIHYCEFLPTFL
HKFLWKANWHYASRCFARADVVTSPTQSAANFLERYTTIENVVPISCGID
LSGYTPSFERGSVLLYVGRITREKQLDVLIRAFAKLNNKDITLKLVGIGE
EVEPLRALAYSLGVSDRVVFCGYLEEGDLRKTYSEASVFVMPSTAELQSI
ATMEAMASGLPVVGADSMALPHLVRDGENGYLFSPGDPDDLASKLTAVIA
LDDADFAAMQRRSLEIVAEHEIDRTIDAFERLYAGSQVSCN
>TWT289 NPL/P60 family secreted protein
MARLHYLLIRKGVCVLHLNPLLPTHPFAAHIPFFLCQACCITCFVLRSYC
FACSLALSRFLGGYLTAVSIRSSFPSRDDRYSRYVPSVGARRRGLLRRSE
GRSAPMASLAVVFISIAVSTVTMPVYAVDTYSVASNPYEVQAVQVGGAHT
LPALNGDAYSVVRRGVSSYRPAVFGLSAALVPVPYTPSSVLDVASEYVGV
PYRFGGADPSYGFDCSGLVKYVFARFGIALPHSVSGQAAAGRIVPRSQAR
PGDLVFMPGHNGFYVGPGLILHAPDYGRSVRVARIWTDNYYIVRVGG
>TWT035 ABC transporter permease protein
MWRPMPENLIRARLLSKPLKPVGETGMSSLKGMWQRRALLSLLIQREIKI
RYKGTAFGVLWSMARPIVQLLVYYFAIGKILGAERGIDQFAIFIFVGFAT
WSLFAEIASTAVVCMTNNGGLIKKIYLPRELFVVTALGNALFTFSIYILI
LMVAAPVLGQMPIDPTKWQGFVGIGIAIVYATALGLVLAPLNVYMRDAQH
FLDVALSILFWLTPIVYSFQRVNGAVHSNIAEQLYLLNPMAIAVMGMQKT
FWTAGSSVHWPADIDARLIIVFLVGLLLLFLAHRIFVKMQANLAQEL
>TWT034 ABC transporter ATP-binding protein
MKNKMSVVNSNAVKLAKSKHYTGVTNDNAILRVSNVSKKFVIQHNRSIKE
RLLNFRVSRANREPFWALKNITFELPIGSSVGLVGHNGSGKSTLLKLIGG
IVRATEGEILSRGRISALIELGAGFHPDLTGRENIYLNGSILGLTKAEIR
RNFDSIVDFSGIEKFIDTQVKFYSSGMYMRLAFSVSVHTDPDLLLIDEIL
AVGDAPFQKKCLNKVTQFKNEGRSIVMVSHVAEQIETVCDKVMVLKNGRL
IYYGTTKVGLDLLRENYQ
>TWT450 unknown
MKKLHVLLPGRAIRPVIRLLIILCASGILAGNSVYSLPSTASINTQFVNF
DDDYIDQIKKIITSIVDLNKKNWKWPVSSSKKVIRGFKPPRNKKEKYLSG
FHRGIDIAAKENESVYAPADGVIKFSGFLANRYVISITHANGLVSSFEPV
KASVIKGQRVTRGQQLGQVQTGLHTNIILGSVKKGLREALNTAVQLLGEY
AGSVAAGPVGAKIGKELAKFVVSSVTKNSALGDGIHIGVRKNGIYINPLL
FFGKIKPSVLLPNN
>TWT765 glycosyltransferase
MHDLSRHPVIIIPTYNERESLPRIVADIRSVLPDINIVVVDDNSPDRTGV
LADRLAESDDRMSVVHRSKKAGLGAAYLHAFSRVIESGARVIVQMDADGS
HSPRDLKRLLSHSQDYDVVIGSRWITGGVVVNWSMRRKLLSKMGSFYSRI
LLRIRVRDVTSGFKVWKAEALRKMDFSSLNSRGYCFQIDLLREAIRSGAS
VKEVPIRFADRERGASKMTGWVILEALLRVTAWGLLDAVKCLFGWLRIDP
RNDTRPACKRRPTKRAK
>TWT088 membrane-associated Zn-dependent protease-like protein
MMFFLGVLIILVFVYIAVALHELGHMLPAKYFGVPVQKYAIGFGPSLFSF
KKRETSYSFNLLPLGGYVQLEGMLPPSENPRRWFKKLMKFAESDSPRAFW
RLPAWKKIIVMFSGPFVNLILATLGYVFVLSVLGLPVIKPVIHEVIANTP
AASAGILPGDEIIAINDTAISSPGQIRGLIQDKDLVTLSLLKDGGTRIVS
LRPLNGSIGVKFSTVNERQSIFDALSSMVKDTVGVTKSLIALPYNLFTGL
ADTLHQRKDGVVGLIGAARISGDIVSAPSISLYDKLRSMIWIFASLNLAL
FVFNMIPLLPFDGGYIAAAVFEGARSRVLLAFRKNDYAPVNISYLLPVTL
LVTAAIIVMSIMLAWIDIVNPLRLG
>TWT564 unknown
MGMIAKHTKRGVKFPRGEQAKPASGWSRIVMIFGELSMTAGVLVGIFYTW
VLYIDSPLTAWEQGNSANLTASQFMRHRSDATETMPVTDRVKDYEDIAVL
FVPRFGNKYKRVIRETTDVTRVLNSKTAGVGHYPHTALPGTSGNFAVAAH
EVGWGAAFGKLSELRLGDKIYVLTPKGWYIYAYRSSEYVKPDGVNVLRPL
PQSFAVPDETYIMTMTTCNPPFSVAERLIAYAVLEKWQADVPHEIVNIVN
S
>TWT495 alanine racemase-like protein
MCQSMISRLATITLESIKNNALLCLEADGDITVDLRADAFGHGLVKIAYT
LYSTGVRKCFVRKAHEKIFLEEIGFTVDVSDAPIKPFSHDIYGLGDNTEC
KAALHLESCVVTCKKLPAGAGVSYCHTYRTQSEENVALIGIGYADGLPFQ
AQGSVEIKKRKYPIIGRIAMDYMVAKVTPDSYKHGTRVTVWGESGAKTWG
LSAGIDPLCLTAGLAYRVEKRWLT
>TWT188 putative UDP-N-acetylglucosamine pyrophosphorylase
MSSESTDTDGVKSDLAIVILAAGRGTRMRSSTPKVLHNIAGLPMVAHVLR
GAQLLKPCKTIVVFRDVRVEQYIRNTFPDVLTVAQSDALYGTGFGVFSAI
PWIRSESYGNTYPNTRHESHAEYELDACDLDTCNPASDRLNDQESLKGGR
HIHTKSGDVTNNKPFPSRVLILYADVPLVPFQLLEELVRKPLKQAVGAIV
TTHLDNPKGYGRVMRDNLGSIAKIIEDSNILPEQSINEVNTGVGIFDTEY
LQDALNKLLKCHIAHSPNQDCVTNQDCVTNQDCVTNQDCVTNQDCVPAAH
TEAHVLSPKVIVTEQIHKKAESEHQHAGQWMCRQDTVGAQNTKEEMRLTD
IVEYFYNNGLRVNSITTSDSELLLGVNNRVQLAKTEKILNDQIIKRWQLY
GVTIKSPETTWIDSTVQLSEDVLILPGCILSGRTRIEEGAVIGPFATISD
SFIGKNTIVKRAEIIDARIEEGAVIGPFAFIRPGTVIGKDSKVGTFVEIK
QSNIGPESKVPHLSYIGDANIGSHVNIGAGNIFANYDGKLKHETCIDDGV
KTGAGNVFVAPVKVGRGAYTGAGSVIRDDIEEGALSLTELKQKTIPKWAE
NRGDG
>TWT149 NPL/P60 family secreted protein
MGRCVRRCFIVALVSVLCSSMLFQTSVAADPTGEPVPPGYPNWNDVERAR
RNQDAKRREVENITGLVMALQDRVNQAVRAAAISAERYQEAKIKLEDASR
RSKSFAELAKNSSLKADLSKKEAGRMIANLYKRGSSNMSLFFSRSEDPEN
LLEMLTLIDRFGGHFDEVYTRAIRDANDSSALRKQADAAHIDFEKLADES
QRAYDAAQHARQAAASAVDEQKARSKVLLAQLAVLQNTTQEVQKRYLAGV
RERRERAEAARRRAALRDKGNHAAATALLSNNPPRSSAVAKVLNFARRAI
NLPYVFGGTGNPGYDCSGLTLMAYRAAGINIGSHSVNSQYYTARAKGQLV
SYENRQPGDLLFWGSGPGSFYHNGIYVGNGMMIAAPDFGDVVKLQPVWGI
PWLQVARPAQ
>TWT797 unknown
MTLRIAMVSMHSHPLAQPGTSNAGGMNVYITEVAKRLAELECMVDLFTLS
NEDYSQDIFRGVRLIGIKPSGRIGPQMVDMLNHVPGFAQKILEHEPYDIF
HSHYWLSGMASDIVSSQLDTPHILNMHTIGAVKNTLLAEGDDPEPPIRLE
SEKRLARKVSKVITSTLTEASAVSRYYGIRFENIAVVSPGVDTTVFYPKG
NCTQENEGGNHLWAPVATNPAGFLAVLSRIQPLKGQDLAIRTLASLRKIM
FDKCPSLIIAGDQSEKYNNYAASLRRMALDLQVEDLVHFTGVISRKQVAM
VMRNAQLLLVPSHSETFGLVTLEAAASGTPVVASLTDGLIDAIVPNITGI
LIAERNPDIWAKNIANLLMNKNRHKSLSRSSVRHAQDHDWTKTAAQILSL
YHQFV
>TWT038 glycosyltransferase
MTNRVLVVVPAHNEALSLPGTLQEIKENLPGFSVLVIDDGSTDATSDAAE
AHSIKVIRIPFNAGVGGAMRLGFRFALRKGFNVVVQVDADGQHNPKYVSE
LINRLNNRHDKPDIVIGARFAGCGNYKLRGPRRWAIFALSKLMSRFAKTN
LTDVTSGFRASGTRAIKLFAEKYPTEYLGDTVESVAIALKEGLVVRQVPV
AMRERKAGTPSHGPCRATLLLLRVVVAALVAPLKSGKSKGCR
>TWT220 unknown
MNGHLPVMLGEVCQLIEPVLGIGDVFIDATLGAGGHSEAILMSSQGALLY
GIDRDAYALALARKRLSGFADRCKFVHDTFDKFDKYLSNLHPKVFLFDLG
MSSMQIDNPDRGFSYMKSGPLDMRMNESDKITAKEILNGYSETALIRIFR
DYGQERYAKRIARQICKARSVSELVTTCQVSQLIRDVCPPHIRKGHPAKR
VFQALRIEVNSELLFLRTALEKALDLLQVGGRIVVLSYHSLEDRIVKHLF
RSVSVSQLPKGFYINKDPEYKLIGKDLKNPKETEIANNPRASSAHLRAVE
RVHSHSQAEAQIVEPRA
>TWT498 UDP-N-acetylmuramyl tripeptide synthase-like protein
MRGCLAIFFGRALLVALRVLRSGGSVLPGVLAEFISPGILIRLIGNSEII
FVTGSNGKTSTTRMAVSILRAHGHEVFTNSSGANMKYGIIASLLAVPKRT
RKGIALLEVDEGHIETLADLLKPSTALFLNLQVDQLNRFHDPGTVLVKLK
NSLAFVKDVLIFNLNEPCFSELLESSLASQKLSVYGFSSSSDILNSIPPT
GLLPHLRGQFSPPGRIESLCHIEHYSARTAHFSIQGVDRLQEIQLRTEGV
HHAQNAAAAFALCMKILGDEFDPNKASSAVSLSTPAFGRDQVISLAGQPV
RILLMKNPRSMQVNLESIAAGSRVMIGIDGGTPDPSWLYDVNLSAIKRAV
VTGSMAWQVALALSYAGVVIDLVEPNLFRATNYFLRHSSSDKFQSFYNKK
SEVLRKSNFDNNQCVTATHLDADFNRDQFGAKDDSAMVMILNYEMSMRLL
RHYRYLDSSCY
>TWT036 glycosyltransferase
MGVSVVMATYNGGPFLAEQLMSILSQTVLPDEIVIADDGSTDDTERIIFR
FRGKFPNLLYIPSEGTRLGPGKNFERAIKRSSQEFIVFSDQDDIWQPDRI
EIQQSALKSNPGAVLLHSNARLVDQDGNMLGDLFSALGITKTILTRINNG
EAFNILLRRNVVTGATVMTRREFALSTLPFPDAWLHDEWLAICGGNRVRV
LDHCLIQYRQHDKNHIGARRLSVREKFLKLFEDTDVRNARLLARTEALTN
FAEEKSGNIFFNTREIGLIRKKLTHERFRSTLGKSRLLRIWPVLKRVSRY
RQFSNFSADILRDLLSSRQHDKP
>TWT309 putative prolipoprotein diacylglyceryl transferase
MHFYIPPPPISGFWLGPLYVHMYSVFMLAGALVLFELTNRRFIVLTGNRE
FTAFAVTSLLIPVILGARLWHVVSHTQMYEHQPFYKVFAIWEGGLGFIGG
VFSGLICFFVIAKIKKVPPFTFLDALAPGILAALCFARLGNYFNGEVFGT
ETTLPWGLKLSHEGFKDLNVEKYFHPIFLYEIILNVFIIVILLVLEKRVF
VKTVFPKGSVFAAFLVLYGLGRFALEPMRYNLQQNSFGLDLNYVGAAAMI
IVGVLIACRHTIASGKLRNSGD
>TWT496 alr, alanine racemase
MTQRTALSNSHAQAFISLGTLKKNLLWLQNEVAPAKVFMVIKANANGHGT
MRVAEVAKMSGIRNFAVLLPKEALLIKRALSPGVRVFTWHITPDCEDLPS
LIENNIEIGIGAEWQLRYIASCVKKTMTCEVLSGYKPALIHLKLDTGLSR
GGCGVKDWQNLVCLAQDFQEMGLIKITGFWSHLSNTSPEEDRRSLKIFTE
NVTPYLASYSRRARPIMHIAASVAALGLPESRLDYVRLGLSCFGYYEKEE
LKGVMTLVAPIIKFLPEQGRAIIACGFADGISPLAVRNNVPLTGRSNRAR
LIEVGPETSVIEICQDIDRRQDNLQNSYDHVPQDPFLNALRVSQNHVILF
GSGGLSELTARQWAESCGTTIDDVLSRVKAELIYLE
>TWT327 dacB, serine-type D-Ala-D-Ala carboxypeptidase
MRLYRPLFYACLLLSFLFFILSDRYGMERTQSPHTVDISQRYFADSSLSL
LPHLLDPDIKHIALDVDGHPELKLRKGNKGKHPIASISKVILALMLIERY
SLSELNDGPNITYDTEDVSFFRNSVKDGDSYAPVYAGLTLTLKQSLIPLM
LPSANNYATSLVKHLYGKSYPKFAREWLDKNGLYNTDIYEASGLDDRNVS
TADNLIVLAKKAYSNPVLRGIMRLKEASIPNIGLVRNTNKALGINGIDGI
KTGSSPAAKSNLLFTAAIKTKNGLIRIYGVFKTEKSYASLYGKLDTLLKR
VRAYFHQRNLLTD
>TWT505 ddlA, D-alanine--D-alanine ligase
MRRLLLLFGGRSQEHSVSYASARALLEHICDEWTVIPVGITKHGDFVYCS
TVSEQDYGEVIDNGNRVVWPSRAGCKKIEVVQARGKSFFVEFDLVFPLLH
GVFGEDGTIQGMLDLLDIPYVGSGVFASAAAMDKHYTKILCSHAGIPVLP
WYLIKGHAWHKNRDSFLKQISDRFTFPLFVKPVDAGSSFGCTFVDFFEQL
PVAIEHALQHGKSAIVEPALDAPEVFCSLIENNGVLQCSELVFVKHSGSK
FYDYSAKYLNPVEFVIPAQFDNTDGYAEIASKVFFELGCRHYARIDFFVT
ESGLVLNEINTSPGLTQKSIFPSSFKSMQYSQVIETILASAYCQVKR
>TWT230 ftsQ, cell division protein FtsQ
MTVIDNAYQNFLYCRKQRKDYERVCKIRTKIIRRFILLACAVFLLFCMLS
AYSPVMSLRSIRVAGNMQVKTDDIVAALRGEFNKPLAFVDPETVRKKLAK
FKLLKEVTVEAKPPGAILVRVSERVPLAFLERPDGFHVLDEDGVSLKVTQ
SPPLGMVRIDVKDGNQEQLVASLGWVIANIPDALKKRVDLISAETPSGIN
LKLDNSTKTVFWGSFQNSKLKAKVLEKLLSIPGHYSSFNVSAPEAPAVS
>TWT606 glmS, glucosamine--fructose-6-phosphateaminotransferas e
MCGIIGYSGPRPAAEVLLKGLERLEYRGYDSAGIAVVTDKAYIESVKKSG
KLNVLKTCLERRTTPIVGSTGIGHTRWATHGEPSDRNAHPHMDTEQSLAI
VHNGIIENSDVLKRELLASGKSFTSETDTEVVAHLLSDAFKKTQDLVQAF
VEVTQRLEGAFAVVAIHKDQPNTIVAAKNNSPLLLGFGQGENFLASDIAA
FAEYTQRVANIDQERIVALSGDSVYITDFAGHPVDYEVHTVSWHPASVDS
SGWSSFMLKEIFEEPQAVENTLKGRTEDGTVILPECDHIRDDLLAIDRVV
LVGCGTAAYAAMTASYSIEAWAGLPVSVELSHEFRYREPVLNSKTLAVFI
SQSGETMDSLMAVRYARQAGVKTISVCNVMDSSIPKESHAVIYTKAGPEV
AVASTKSFVCQIVVLYLLALYLGQLRGFRSIFPRQKAVCELNRLPVKLKQ
VLEIYESVRQLAHWMSDSRSILFLGRHAGYPIALEAALKLKELAYIHAEG
FAAGELKHGPIALIEPGQPVFVIVPSPVGSPILHAKVISNIREIKSRGAR
IIAIAAEGDSAVLPHTDSVLRIPLTRYSFEPLLSIVPLQIFALELAADKG
FDVDRPRNLAKSVTVE
>TWT642 ispH1, IspH protein 1
MHHTGLGSGVAKRVLLASPRGYCAGVDRAVIAVEKALERHGPPVYVRKQI
VHNVHVVGSLEKRGAIFVDQVDQIPPGAVTIFSAHGVSPAVVHSANERGL
QVIDATCPLVTKVHREVIRFSKAGYFILLIGHSGHEEVEGTSGHAPDRVL
IVNSPDEADTIDVPHTDKLVWLSQTTLSVDETLETVKRLRLRFPHIQDPP
SDDICYATQNRQAAVKKIAPLSDLVIVVGSANSSNSVRLVEVALENGAKA
AVRLDYADELDPALLDKVDVVGVTSGASVPEILVRDLLEVLARAGYTKVE
SVQTAVEDLVFSLPKGLRESRK
>TWT278 lepA, GTP-binding protein LepA
MTDRVLPEQIRNFGIIAHVDHGKSTLADRILQLTGAVSDRDMREQYLDRL
YIERERGITIKSQAVTLQWDCDATQYVLNMVDTPGHVDFTYEVSRSLAAC
EAAVILVDATQGVEAQTLANLHLAIENNLLIIPVLSKVDLPSADVEGATL
ELSEVLECRVEDVMHVSGKTGYGVKELLDLIVRKAPPPKGDVTSAPRALI
FDSIYDSYRGVVTYVKMCDGTIRVGDKIRMMSTGAEHTLLEVGVSNPEPQ
SRHSLSVGEVGYFITGVKDVRKSRVGDTITTDTHTATVPLPGYSNPKPMV
FSGIYPLNGNEYSALREGLDRLKLSDASIVYTPETSAALGFGFRCGFLGL
LHMEIVSERLNREFGLATISTAPSVAYEITPDGEKTLVVMNPSDFPSGKI
KEIKEPTVKVSILSPKEYIGSIMELCQARRGVMQGIEYFGSVRAELIYVM
PLAEIVFDFFDSLKSRTKGYASFDYNPEGSQPADLVKVDILLQGNKVDAF
SAIVHSSKAYSYGSSISKRLSELIPRQQFEVPIQAAIGSRVVARETIRAV
RKDVVAKCYGGDITRKRKLLEKQKQGKARMKLIGRVEVPQEVFVATLSSY
K
>TWT512 lpsA, lipoprotein signal peptidase
MTTRTLRFYALVGFLVFLDQVTKYLAHAYLARDFIVIPNLFRLTLAKNSG
AAFSFGTGFSWLFFLLGIIALIFIGWFLPRTTGSIVFLALLQGGIAGNVF
DRLFKPPYFGNGEVVDFLNTPLLSGVVFNIADLFILAGVFGTFLFLKGSK
>TWT356 manC, Mannose-1-phosphate guanylyltransferase
MDCSELYSVIPAGGIGSRLWPLSRAASPKFLHKLTGTETSLLRDTWDRLV
PISGVDRIMVVIGSDHFDAVTSQLPELKGHNVILEPEPKDSTAAICLAAA
ILNTREPDVIIGSFPADHVIKTSPLFQQSVAQAVVAANEGYVVTIAITPT
EPATQFGYILCGDSAGIKGAPQVLSVKRFVEKPSQKDADRYLSSGKYLWN
AGMFIAKACVLLEQLEKARPDIHSLIIDIANSPDLDSALKKNWPKMPRIA
IEYSVAEPCAAEGRMVTVPAKFEWNDAGDFSSIARLNSRGGSDLVILGET
SRVLSDSATGIVVSQTDRIISVIGTKDIVVVDTPDSLLVTTKDDAKKVKQ
IVEALRLSGRDDVL
>TWT737 menC, O-succinylbenzoate-CoA synthase
MYGRHTISIILREIFRLMDYPSIDTLLESAHIVTLPMKYPFMGLSERQAV
LFEGPNSWAEYSPFMGCNDTRMWLASAIEYGWGNTNVLSVPNLDLDNTNF
ASRSKYGYIANPQTSNKDHSDNKRFYTQTKNHREIPVNAILPDIPASKMS
EILGKDLQGCKCVKIKVGKHFQDRDIHRIRAVLDFMGADTMLRLDANCKW
NVSETLNNLDVLEDNDLLENVSYIEQPCRTTRELITLKQKMDTRGYVTKI
AIDESLRDLLLHWQKNRKWSNNSGITYTTELRETLSACDMLVLKLQPMGG
MRAVADLLESIKNNIKVNVGYTVSSSLETSLGIEMGLALALNLPNITLPV
GLATAGLLDADITDDPLLPNKGYITPRKIEVNKKLLNRYAADKRHVVWWH
RRIRAAHRALFQDLSD
>TWT661 mscL, large-conductance mechanosensitive channel
MGACMFAGFRDFIARRNVVDLSAAVVIGAASTAVINAIVDDIFSPLISAA
LSSSKIENSLVLTIPTLSHGHVQLKFGTVLLALIKFVLVSAVVYFVIILP
LNHLKDIRRTLGNSLPGPLGALSAIISGGKNTKDEDPDKDELADGQSSAE
TKVGNDGTGSEELSDTRPSGSLEGDTVTKLLMEIRDLLLLMGEMDNKKSK
DHSERGL
>TWT508 murA, UDP-N-acetylglucosamine1-carboxyvinyltransferase
MKLDSTPDRFVITGGSPLRGEIAVKGAKNLVTKAMVASMLGNSQSVLTNV
PNISDVLIVRRLMEAYNVSVRATQNDTLVIDPILLGQCSRGDIDVYAGSS
RVPILFCGPLLHKTGQAFITGLGGCRIGERPIDFHLQALRKFGASHEKLP
GGILLSTKKRLKGASVHFPYPSVGATEQVLLTAVLADGVTELRGAAIEPE
IMDLIAILQKMGAIITCARDRVIFIEGVDSLSGYTHHAISDRNEAASWAC
AALATRGDIFVRNAEQAHLLAFLSVYRKVGGVFEIKDDGIRFFHPGGNLN
PVVVETDVHPGFSTDWQQPLVVALTQASGRSVVHETVYESRFGFTEALNR
MGADISVHENGFQGTLRRVPHRAIEQAAVINGPTPLTGQDIDVPDLRGGF
SHFIAAFAAEGKSIITNAGIISRGYENFVHKLERLKVDFEA
>TWT718 murB, UDP-N-acetylmuramate dehydrogenase
MVSFSEITTLGVGGSIACFIECSPDEFVERAPGLFRPGHHVLVVGGGSNL
VASDCPFPGTVVRLKSRDTIVSDDGDYTRFSISAGTSWDDLVSYSLDLGF
DQLSPMSGIPGTFGGALAQNISAYGAAVRDVLGSVEVYDACTSEVVTFGL
EDMRYGYRTSALKNVRNKVILGGTLLLKPGPTPVLHRQLANALKVDLGTY
CSGKQVRDQVLRIRAEKGMLPRYLVPKGFDVCNTSSVGSFFVNPIVSKEH
LSRLRRLVPQGALNSSVIQTDEMGGVKVSAAFLLEQSGFEKGFCISGSQA
AISTQHSLAIVNRGGATAAEVIELAGLITRTVSRKFDIHLIPEPVFVGLE
L
>TWT229 murC, UDP-N-acetylmuramate--alanine ligase
MGIYAKDVPLPESINRAHFCGIGGSGMSAVARLFLQLGISVSGTDRSDSI
TLSELSQAGAIVKVGHDPAMLEGVDTFVYSGAIDSSNPEYAYAERARINL
LHRSLALKWITRGKRLISIAGSHGKTSTTAMIATALHVLGNKCGVANGSY
MNFFSANALLGLNDLFVIEADESDGSFLFYDTDISVVNNISMDHVDYYGS
QSALEGSFFDFSLRSSDAAVISLDDAACIKIASKLLQSSGSRGPSKRVIT
FGKNRSADVCLYEMGCMNPARFTVLYEGRFYNAGFKGLFGEHHAVNTCAA
LSVLLCLGYGISESLEAILSFSGTRRRLELHFDSGGKDGIKIFDDYAHHP
REIRTALTAIRSVQHTRLIALFQPHLYSRTAALHREFASVLENCADFTII
LPVYAARESPIPGVDAKIIFDAYRDKRNVVMLEGFDHTLSFFRQFLRDGD
LVITLGCGDVYKIIPSIVEQLRSAR
>TWT226 murD, UDP-N-acetylmuramoylalanine--D-glutamateligase
MILLDPMTPFYALVLAMILILMSSGRKFRILSEMKCAGDLKDLRRGLEMS
RVEGLTSWYSDWQGLSAAILGIGVSGFAAADSLRELGVDVTVYAPEKHTR
YNKLLDAIGARYVCAYLDELCEVDVDFIVVSPGISPDNPVIKRLRDRQIP
ILSEIELAWRVRDKVNTCPWILITGTNGKTTTALLTGSMLAKDGARVAVC
GNIGTPVLDAVRNPKGFDYLVVELSSFQLSLLPMHGNGAVKGFSSACVNL
DEDHLEWHGAKELYYCAKSRVYHGTTGFCVYNLDDEETKKMVEQACVARN
VRAIGFGLCVPDVGQVGIVDGILCDRAFLSARKDSALEITSVEKLEKNKL
SMRHIISDVLCAVALARSVETNPLSISRALDEFCLSPHRTEVVAKEMGVM
WVNDSKATNPHAVIASLSNFSRVILIFGGLMKGVDVSGIFDRFYETIKAV
VVIGKNQSFVGNIKCKKIVCIPDSNDPMSEAVAAADLLATPGDTVLLSPG
GSSFDQFESYEHRGNCFINAVKDLVKRK
>TWT225 murE, UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase
MDNCRFIHCPWYWFILCGLAIFVTLQGKPYRLSDLIKQTGVRLTDCSNQF
SDRFVSGITQIAQSVERDDIFVAFQGKTRHGVEFLDQVQSCAAVLTDNKG
RHIMQSDCLPTRSTPILVTDSPRSDLIVLAKRVYPIDDIRIFGITGTNGK
TSTMHIAAKLLEMMGISCGISTTIGSSASESDSCLTTPELCQLYARIFTA
KQARADFFALEASSHAINRGRLGDIVLEVAAFTNLTPEHMEEHKNMEAYY
QAKKALFLNKRSNSAVINIDTPYGIRLFKETGCSASVISENTKYGLDHKL
FWQASVRRVGLSFGFTLISPSGYRVESSISLLGKAFALNTCMAIVILCNL
GIDIERIDSVLRKAGGLKMVLPGRMEVFQTGNSPRVIVDHGHTVDAVETA
LVAAKSITRGRLITIINADGQRDPSKRKHLGQLCGAYSDKLFITDGHSRF
ENPAEIRRMILDGVEGPRRQVEQIPSMTQAVLAAIDIARSDDTVLCSGFG
DDPYLDVLGKKIPYSLRDEVRRGLERFAQGT
>TWT223 murF, UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanine ligase
MLIRRADIQRVTGGILHNTSLSESLLPINGRLKIDSRNISQGDIFVAHTG
TKFDGHEFLYQAKQSGASLAIVTRVQEIDLPQLLVGNVTEAMHAIAGFKL
CLSRDTITVIGITGSNGKTTTKSVLAYVLSKFGNTVATHGNQNNEIGFPI
TVSRIEPLTKYLVLEYGAFKPGDIDCLKKIAVPDIAVLLSAGHAHVEKSG
SLESVCSMKAELARDLPEGSKVLLNYDDPRIARLSVGNRYYFGTDKRAHF
RASHVETNIIKTRFIVTYQKGSVEVETKLIGKHQVSNVLAALSTLVLLGF
DAEVCARYISEVNPIDGRMQYIPLGDFSIIHDAYNASFESVKCALDSLVV
LGSLAKRRIAVLGRIHDMGELAQDVYRQLVKQFLDTDINLLVIVSEKQMY
LIAKELAKGVPNKEIVWFEDLETAKHEIFDLFSPGDIVLFKASNAENFSS
LVESVKHKAGKFAG
>TWT228 murG, UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
MSRILLAGGGTAGHVNPLLALADVLKVSGHATFALGTSEGIESRLVPNSG
IDFFTIPKLPFPRRTSRHILCFPFKFFSSVKLVRSILIEHKIQVVVGFGG
YVAAPAYAAAISLNIPYVVHESNARPGLANLLAAHFAKCVGISVIGALPC
GKLVGTPIRRDLTAAASFDPVLAKEKLGLDPVRKLLLVFGGSQGSAKINM
HMRAALPRVLKLCDEKNYLWQVLHITGYGDSIDVNMPHYSSVRYMDSMGY
ALSAADLVVSRAGSSTVAELCTFGIPAIYIPYPFGNGEQRRNVSHMESAA
RIIQENDLSQIRLEDELLELMTDDERREAMSIAAKRFAICNAAQNTASLI
ELALSS
>TWT224 murX, phospho-N-acetylmuramoyl-pentapeptide-transferase
MIAILLAVAFGITFTLFTTPFFIRLFRKIGWGQFIRLDGPRQHAIKRGTP
TMGGLVIVVASIISYFLANFFLGLSVEPSGLLVIFMFVGMSLVGFLDDIL
KVRKQHSGGLGPFYKVVLQSFIAVPFALLTFLVKDARGIPHSSMSISFAR
DTGINFSALFSLGIIGVFSAWILYLLWINLIAVSSVNAVNITDGLDGLAA
GAMIFTMLAYVVIGFWQSGQNCARKSLPLENISKCYSVNGPLDMSILAAA
ILGSLLGFLWWNTNPSKIMMGDTGALALGGAAAALSILTHTQLLFLVLGG
LFVIEAGSVILQIAFYKKYRRRIFLMSPLHHHFELKGWAEITVVVRFWII
AGLFTALGIGLFYADWLYS
>TWT776 pbpA, penicillin-binding protein
MSNMLSVKHVDKKNRDGRAIDPALRVISYIVVAMFLMIMLSASGIQGLFA
DNFLKDPRNSRVLYAAERVYRGPIFVGNERVAYSEKRGKSYKRFYAHPEL
YSAITGYFNNVHGRSGLEKYLNSELSGANPVGLSRMFEGAENGRSVLLTI
NEKLQKIAWRALEGFRGSAVIIEPSSGKILALVSRPGFDANKLSNDTNVE
ESYKKLLKDPAKPLINRAASLYHPGSVFKIITMATALETGRYDLDKEVTD
SNLLTFPGRRFFIENSGACSGRNKINLEQALAFSCNATFGKIATDLGGEL
ISKMAERFGFGKKITIPIPFQASEYPVTGDSAQLAQSGFGQWEIWATPLQ
IAMISAAIANNGKLMKPNIVQRVKGPDANTIKEFTPEMLGRVATQETVKK
LSKAMESVVEYGTARRGKIRGIQIAGKTGTAEDGTGRNTLWFTGFAPVDR
PFLAVSIVLEEQKGDAGTIAVPIAKKLIEEALNER
>TWT222 pbpB, penicillin-binding protein 2
MKRSSSRGIATLFVVALLSSVFMARLVDIQIIRAKELGRDSYLQRSKTHV
IPGVRGNIVDAYNRTLAESLTQYRLVLSPSRVSDYWANGKKVIPSAAYQK
ISDVVPITPAEISDKVTNALRKNKNSQYLVIFDAIGVDKKGILEKENIPW
LYFERVYKRIYPFGGVAGNLLGFLNIDQVPQAGLELSYDNCLSGHDGKED
YLASPDGVPIPGSNRVVQPAKHGGQLALTIDSDLQWYTQQILKQYSELES
ARWGMVAIVSVKTGKVLALADYPTVDPNNVGDTDAINRGARTFSDPYEPG
SIFKPVTASILLDAGGLTPSSRFRVPYNFRAPGDVDISDDERHADMDMTL
TGILVASSNSGMSIASRSVDLAERYRYLRNFGFGASTGLRFPAQSEGLLG
NYKLWDQQTRYASSFGQGISATILQLASAYQTIANGGVRRPLSMVTSCGD
KPTESKKGTSGVFGRVVSQKSASATSNMLEMVYRHSWLHNLWRIPGYRIC
AKTGTAQVAAGNGKYGKSYIVSVAGYAPAEDPEFVVITSMYKTKQNTAAA
VAPVFQKVMSHVLKKYRVLPSTTLPTELALR
>TWT432 rfe, undecaprenyl-phosphatealpha-N-acetylglucosaminyltransferase
MIVYLSVALFAALVTATSVYCLLKIAPKFWALREVRPRDVHTVPTLRIGG
IPMFVAFLFSIALARFIPYFSDVFRTADPVLTSLVIAVSVITLLGFLDDL
FELHWLIKLLGQIFSAAIVSVMSRGIFHSFTGGDLSWLLTIASIVLIVTT
MNAINFIDGLDGLAAGVCLIGNGVFFVYIYFFTREISPSNYFNLVGLLAA
ILFGICAGFIPFNWRPAKLFMGDSGALLLGLVMSVAATTAVAQASAVTFV
RRAHYVPAFIPILLPFAVLGLPILDLLFAIMRRLLSFKSPFNPDKKHLHH
RMLHMGHSSVATVVIFYAWSGVVSVGMLLFLFTSTIFAVLFLLFGVLVCL
IFTFLPIVRKRSWNRN
>TWT032 rmlA, glucose-1-phosphate thymidylyltransferase
MKGIILAGGTGSRLWPITKCISKQLMPVYDKPMIYYPLSTLMMADIREIL
VITTTQDYDQFRRLLGDGGQWGIKLSYAQQLSPGGLAQAFLIGESFIASE
SIALVLGDNIFHGSGLGTSLRQHRSIQGALIFAYHVSNPKDYGVVTFDAD
GKAVSIEEKPESPKSNFAVPGLYFYDNQVVDIAKQIPLSARGELEISSVN
NFYLEKDQLRVYPLARGTSWLDTGTFDSLVQASEYVRVIEQRQGFKVGCV
EEIAWRAGWIDDDQLAKLANGLMKSGYGKYLHYLLSGKHGFS
>TWT030 rmlB, dTDP-glucose 4,6-dehydratase
MTHILVTGGAGFIGSNFVRRAIENKYPEIRDCTVTVLDALTYSGNINNLS
PVRSSSRLRFIHGDIRDEDLLSEIMPNVNYVVHFAAETHVDRSIKNASAF
VETNVLGTGRLLEAAARNNIDRFIHISTDEVYGSIESGSWDENQPLLPNS
PYSASKAASDLLVRSYHKTYDLPVCITRCSNNYGPYQFPEKVIPLFVTNL
IEDKEVPLYGDGTNVRDWLHVDDHCRGIYIVLTKGRSGEIYNIGGGLELS
NADLSQIILEVMEKSWSMVKRVKDRPGHDKRYSVSINKISTLGYRPEVSF
EQGLAETINWYKDNSSWWKPLKARAAL
>TWT031 rmlC, dTDP-4-dehydrorhamnose 3,5-epimerase
MELRNLKVNGCLEVTPEVHVDSRGSFSEVYRFDVLEKEIGYPLRVAQVNR
SFSKKAVLRGLHYSLAPHSQAKYVMCANGAVLDFVFDLRLGSPSFGVWDA
VLLDSVGCRAVYIPEGVGHAFIALSKTATVNYLCSATYDPEREKSINPLD
KNLNLEYPFTTPEIVLSERDAAAPTLPEAQKGGFLPKWDECRWDECRATP
ETHGNIR
>TWT029 rmlD, dTDP-4-dehydrorhamnose reductase
MSLKCLITGGGGMLGRDIRSVFPESVALTHDELDITDEYAVLDAARNKDL
LINCAAYTQVDAAESNAAKAYAVNEAGARAVAKAAARRSIRVVHISTDYV
FSGTAIRPYPEDHPHSPLSVYGKSKAAGEKAVLEEYSKGSFIIRTAWLYG
QYGNNFVKSILKACRTQDIVTVVNDQYGQPTWSLDLAKQIKLLAESDAPC
GVYHGTNSGKTTWFDFAGKVAALGGYDPKRIIPISSAQFVRPARRPGYSC
LGHDAWTAVGLEPMRPWEDALNDAWAAGVFAECIAGQ