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# Streptococcus pyogenes phage 5005.3

>M5005_Spy1728 periplasmic component of efflux system
MFQLRKKMTRKQLALLSAGVLTCVVGGSYLIMNHQQQEIVSSVNKVKALT
IKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKEVFVKKGDVVKVG
QPLFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEIN
TLKSRYNTAPDESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKAN
ATATTEKGKLEYDTVKSDTAGTIVSLNTDLPNQSKSKKENETFMEIIDKS
KMLVKGNISEFDRDKLKIGQKVEVIDRKDNSKKWTGKVTQVGNLKAEEKG
QGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLIGSHTYVNVLNNVPEAG
KIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVEVTSGLTMQ
DKIAQPLPGMKDGMEVGSIVKP
>M5005_Spy0247 D-alanyl-D-alanine carboxypeptidase
MTKRIILTIFTFICFSVMPLVHAEDVMDITRQAGYTVSEVNRPKSSIVVD
ANSSDILWQDNIDIPRDPASMSKMFTLYILFEELAKGKITMDTTITATPT
DQAIANIYEISNNNIVAGVAYPIRDLITMTAVPSSNAATVMIANYLSNND
ASAFIDRVNATAKQLGMTNTHFSNASGAAAQAFQGYYNPTKYDLSASNIT
TARDLSKLLYAFLKKYPEIISFTNKSVVHTMVGTPYEEEFHTYNHSLPDN
QFGMKGVDGLKTGSSPSAAFNAMITAKRGKTRLITIVMGVGDWSDQNGEF
YIHPFVNALTEKGFKDSKTLSKKARQKLEKLVPQTKKETSSKQQHFKATK
KQSYLERVEDFMNHNHTFLLICLAIFIITILLLSLVVFAMGRQ
>M5005_Spy0447 glycosyltransferase involved in cell wall biogenesis
MFVIGIPTLNEADNISRLVKQIDEYAVNLGKEIIIINSDSKSTDGTPQIF
LETKTYNTKVSIVSEAKGKGYNVRNIFEYAINHVPNFSGLILIDGDVVSM
KKMWLEKMFIAIESGNDLIIPNYARKSFEGNATNHFIYPMLVKIFKRDMP
YQCISGDFGFSRGLIKDLTLKCNWHKYTLGYGIDIFLTLTAILKSYKIKE
IDLQSKIHKKSFEKIEKIFLEVSQSFFETINDNSLNQDKLRLNINFESHS
RQFIKSSDILSSNDIENLKLRALFLLQEEKQYLHGLSEVEWDGILSNTIN
NIYRYSSEEHSLYLLPLYLLRVYNYLKYN
>M5005_Spy0425 glycosyltransferase
MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQHFTTNPRETYDLVHLN
TYGLKSWLLMIKAQKAGKKVIMHGHSTEEDFRNSFIFSNLLSPWFKKYLC
HFYNKADAIITPTLYSKSLIESYGVKSPIFAVSNGIDLEQYGADPKKEAA
FRRYFDIKEGEKVVMGAGLFFLRKGIDDFVKVAQAMPDVRFIWFGETNKW
VIPAQVRQMVNGNHPKNLIFPGYIKGDVYEGAMTGADAFFFPSREETEGI
VVLEALASRQHLVLRDIPVYYGWVDQSSAELATDIPGFIEALKKVFSGAS
NKVEAGYKVAQSRRLETVGHALVDVYKKVMEL
>M5005_Spy1435 phage scaffold protein
MAEENVTTETTEQVDTQKEAVEHPKQEHERTFTRADISKMMAAERTKWES
EQSEAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRI
ETHSLLVEKGLPLDFIDIVLTTTAEEVKANIDNLQTIFDKAVEKRVNDRL
TQKPPRTGNGSVGMTKADIMAIEDDDERMRLIAENRNLF
>M5005_Spy0622 phosphoglycerol transferase
MKKFKTLITGFINTRLGFIITLLFCYWIKTLWAYHTDFSLDLGNIYQVFL
TIINPIPLAFLLLGVALYVKNTRAFYICSWVVYIILNILLISNSIYYREF
SDFITVSAMLASSKVSAGLGDSALNLLRIWDIIYILDFIILISLSIAKKI
KNDQRPFNKRAAFAITALSSLLLSINLFLAEIDRPELLTRGFSNTYIVRA
LGLPAFTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHYAAPDPQYFGI
GKGKNIIVLHLESFQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPN
FFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYGGENTQFATPSILAQKG
GYTSAVFHGNVGTFWNRNNAYKQWGYNYFFDSSYFSKQNSKNSFQYGLND
KYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGESSEEGFPLAKTDD
ETINGYFATANYLDAALKSFFDYLKATGLYDNSIFVLYGDHYGISNSRNS
SLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKETFGGEIDALP
TLLHILGIDTSQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLY
NTQTGLEITNPDEMTIAKTKEIRSAVAQQLAASDAIQTGDLLRFDTQNGL
KAIDPNQFIYTKQLKQLKDISAKLGSESTSLYSKNGHKSTQKLFKAPSYL
ELNPVEADAATSELKEDNPKNKE
>M5005_Spy1530 putative Fe3+-siderophore transport protein
MKKISKCAFVAISALVLIQATQTVKSQEPLVQSQLVTTVALTQDNRLLVE
EIGPYASQSAGKEYYKHIEKIIVDNDVYEKSLEGERTFDINYQGIKINAD
LIKDGKHELTIVNKKDGDILITFIKKGDKVTFISAQKLGTTDHQDSLKKD
VLSDKTVPQNQGTQKVVKSGKNTANLSLITKLSQEDGAILFPEIDRYSDN
KQIKALTQQITKVTVNGTVYKDLISDSVKDTNGWVSNMTGLHLGTKAFKD
GENTIVISSKGFEDVTITVTKKDGQIHFVSAKQKQHVTAEDRQSTKLDVT
TLEKAIKEADAIIAKESNKDAVKDLAEKLQVIKDSYKEIKDSKLLADTHR
LLKDTIESYQAGEVSINNLTEGTYTLNFKANKENSEESSMLQGAFDKRAK
LVVKADGTMEISMLNTALGQFLIDFSIESKGTYPAAVRKQVGQKDINGSY
IRSEFTMPIDDLDKLHKGAVLVSAMGGQESDLNHYDKYTKLDMTFSKTVT
KGWSGYQVETDDKEKGVGTERLEKVLVKLGKDLDGDGKLSKTELEQIRGE
LRLDHYELTDISLLKHAKNITELHLDGNQITEIPKELFSQMKQLRFLNLR
SNHLTYLDKDTFKSNAQLRELYLSSNFIHSLEGGLFQSLHHLEQLDLSKN
RIGRLCDNPFEGLSRLTSLGFAENSLEEIPEKALEPLTSLNFIDLSQNNL
ALLPKTIEKLRALSTIVASRNHITRIDNISFKNLPKLSVLDLSTNEISNL
PNGIFKQNNQLTKLDFFNNLLTQVEESVFPDVETLNLDVKFNQIKSVSPK
VRALIGQHKLTPQKHIAKLEASLDGEKIKYHQAFSLLDLYYWEQKTNSAI
DKELVSVEEYQQLLQEKGSDTVSLLNDMQVDWSIVIQLQKKASNGQYVTV
DEKLLSNDPKDDLTGEFSLKDPGTYRIRKALITKKFATQKEHIYLTSNDI
LVAKGPHSHQKDLVENGLRALNQKQLRDGIYYLNASMLKTDLASESMSNK
AINHRVTLVVKKGVSYLEVEFRGIKVGKMLGYLGELSYFVDGYQRDLAGK
PVGRTKKAEVVSYFTDVTGLPLADRYGKNYPKVLRMKLIEQAKKDGLVPL
QVFVPIMDAISKGSGLQTVFMRLDWASLTTEKAKVVKETNNPQENSHLTS
TDQLKGPQNRQQEKTPTSPPSAATGIANLTDLLAKKATGQSTQETSKTDD
TDKAEKLKQLVRDHQTSIEGKTAKDTKTKKSDKKHRSNQQSNGEESSSRY
HLIAGLSSFMIVALGFIIGRKTLFK
>M5005_Spy1613 mechanosensitive ion channel
MTFILHYLEQSHIENIGLTIFKKLVSLIILLLFFAILKRVTNYLFEKTIN
KSFAYSRQSEARKKTLSKLTHNILNYLLYFLLIYWILSLFGIPVSSLLAG
AGIAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDNVTISDIEGSVFGVG
IRTTQIRGFDGTLHFIPNRSITVVSNKSRGNMRALIEIPLYSTVNLSQVT
RIIDEVNQKELPNHPQIVGKPNILGPQNNSNGQFTFRIAIFTENGEQFKI
YHTFYRLYQEALLKEGIQLPTAISYSITSKS
>M5005_Spy1072 protein DltB
MMMFFSHIPYMEPYGNPIYFVYLILAFLPVIIGIFKQKRLSTYETLVSLV
FILFMFGGDHYQQLVAFLFYLLWQIISVFAYQKYRENANSAGVFYLAIAM
ALFPLIWVKVAPLTGPSSQTLFSFLGISYLTFKSIGMIIEMRDGTLQEVR
LPDFIRFMIFFPTFSSGPIDRFRHFQEDYHKLPERDDYFAMLNKAVMYLM
LGFLYKHIISYCLGGILLPLLENKALMVGGYFNKETILVMYVYGLNLFFD
FAGYSMFAIGISYLLGIRTPENFNMPFLSASLKDFWNRWHMSLSFWFRDY
VFMRLVHLLIKHKTFKNRNVTSGVAYLVNMLVMGFWHGLTWYYIAYGLFH
GIGLIINDAWIRKKKEINRHRKKKGLSPLFQSRAFHVLCIVVTFHVVMFS
LLLFSGFLNDLWFNRPLH
>M5005_Spy0426 1,2-diacylglycerol 3-glucosyltransferase
MRIGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRDVKRFED
PTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKHYNLDIIHTQTEFSLGLL
GKMIGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLD
GVICPSRIVLNLLEGYEVTIPKRVIPTGIPLEKYIRDDITAEEVTNLKAE
LGIAGDETMLLSLSRISYEKNIQAIINQMPAILAENAKIKLIIVGNGPYL
QDLKHLAMQLEVDKHVTFTGMVPHDKVALYYKACDFFISASTSETQGLTY
IESLASGTPIIAHGNPYLDDVVTDKMFGTLYYAETDLTDAIIDAILKTPV
MDKRLLAKKRYEISAQHFGKSIYTFYLDTLIARNSKEAQKLSLYLNHSGK
SSSLKLVQGAIHLPKRAAKVTAITSVKVVKAPIKLVHAIKDFLD
>M5005_Spy1365 phospho-N-acetylmuramoyl-pentapeptide-transferase
MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHLAKAGTP
TMGGTVFLLVATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDD
FLKIFKQINEGLTAKQKLALQLVGGLMFYFLHVSPSGISSINVFGYQLPL
GIFYLFFVLFWVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQSQF
DVLLLIGAMIGALLGFFCFNHKPAKVFMGDVGSLALGAMLAAISIALRQE
WTLLIIGIVYVLETSSVMLQVSYFKYTKKKYGEGRRIFRMTPFHHHLELG
GLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILYVF
>M5005_Spy1674 pheromone-processing membrane metalloprotease
MLGIITFIIIFGILVIVHEFGHFYFAKKSGILVREFAIGMGPKIFSHVDQ
GGTLYTLRMLPLGGYVRMAGWGDDKTEIKTGTPTSLTLNEQGFVKRINLS
QSKLDPTSLPMHVTGYDLEDQLSITGLVLEETKTYKVAHDATIVEEDGTE
IRIAPLDVQYQNASIGGRLITNFAGPMNNFILGIVVFILLVFLQGGMPDF
SSNHVRVQENGAAAKAGLRDNDQIVAINGYKVTSWNDLTEAVDLATRDLG
PSQTIKVTYKSHQRLKTVAVKPQKHAKTYTIGVKASLKTGFKDKLLGGLE
LAWSRAFTILNALKGLITGFSLNKLGGPVAMYDMSNQAAQNGLESVLSLM
AMLSINLGIFNLIPIPALDGGKILMNIIEAIRRKPIKQETEAYITLAGVA
IMVVLMIAVTWNDIMRVFF
>M5005_Spy1019 phage scaffold protein
MENEEILEQSGAQEEAKEQTFDDILSDPKKQAEFDKRVAKAIDTARNKWV
AETEEKENEAKRLAKMNAEQKAQHEKAKLEARIAELEAERTLSEMKSAAR
TMLSEANINISDALLSQLVSTDADKTKNAVEAFSEAFSEAIEKEVKERLK
SPTPKKSNGNTGLTKEQILAVKDTAERQKLIAENIGLFQ
>M5005_Spy1556 hypothetical protein
MFQKLKNLIDRYSWFVFIMMILVLFLNYIYPFDPSLSGLQLEWLIMTQVF
PGLGIVCAMVAIIFKKFNLFVLALILYFALWLKLFLAFSFFTYFLGV
>M5005_Spy0644 periplasmic component of efflux system
MWKQQRNTLTADIAKEPYSTVSVTEGSIASSTLLSGTVKALSEEYIYFDA
NKGNDATVTVKVGDQVTQGQQLVQYNTTTAQSAYDTAVRSLNKIGRQINH
LKTYGVPAVSTETNRDEATGEETTTTVQPSAQQNANYKQQLQDLNDAYAD
AQAEVNKAQIALNDTVVISSVSGTVVEVNNDIDPSSKNSQTLVHVATEGQ
LQVKGTLTEYDLANVKVGQSVKIKSKVYSNQEWTGKISYVSNYPTESNAG
STTPAGSTGAGSSTGATYDYKIDIISPLNQLKQGFTVSVEVVNEAKQALV
PLTAVIKKDKKHYVWTYDDATGKAKKVEVTLGNADAQQQEIHKGVAVGDI
VIANPDKNIKPDKKLEGVISIGTNTKPEKDSQSKNKKSGVDK
>M5005_Spy1160 penicillin-binding protein
MANPNGSVTIHAKIGTVETCITDNSDQTLVTYNLNVVAYNTNNEDNIAVA
VMYPHITNISAKM
>M5005_Spy0420 glucosyltransferase
MTLLSIIVPCFNEEANILPYFEEMHQLETSMTNQLAFEYIFIDDGSKDNT
LGILRELAARFPNVHYLSFSRHFGKEAGLLAGLKEAKGNYITVMDVDLQD
PPELLPIMYAKLKEGYDIVGTRRQNRQGEPLIRSMCSNLFYGLIKHLSDT
EMVNGVRDYRLMTRQVVDSILELGEVNRFSKGIFSWVGYRITYLSFENQK
RKYGKSRWHFWELLRYSLDGFINFSEMPLTIATWTGTFSFLISIFAILFI
IIRKILFGDPVSGWASTVSIILFMGGIQLFCMGIIGKYISKIFLETKKRP
LYIIKEKH
>M5005_Spy1469 phosphotransferase enzyme family
MTTTEQELTLTPLRGKSGKAYKGTYPNGECVFIKLNTTPILPALAKEQIA
PQLLWAKRMGNGDMMSAQEWLNGRTLTKEDMNSKQIIHILLRLHKSKKLV
NQLLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFKS
EVATIVHGDIKHSNWVITTSGMIFLVDWDSVRLTDRMYDVAYLLSHYIPR
SRWSEWLSYYGYKNNDKVMQKIIWYGQFSHLTQILKCFDKRDMEHVNQEI
YALRKFREIFRKK
>M5005_Spy0384 surface antigen
MIITKKSLFVTSVALSLVPLATAQAQEWTPRSVTEIKSELVLVDNVFTYT
VKYGDTLSTIAEAMGIDVHVLGDINHIANIDLIFPDTILTANYNQHGQAT
NLTVQAPASSPASVSHVPSSEPLPQASATSQPTVPMAPPATPSDVPTTPF
ASAKPDSSVTASSELTSSTNDVSTELSSESQKQPEVPQEAVPTPKAAETT
EVEPKTDISEAPTSANRPVPNESASEEVSSAAPAQAPAEKEETSAPAAQK
AVADTTSVATSNGLSYAPNHAYNPMNAGLQPQTAAFKEEVASAFGITSFS
GYRPGDPGDHGKGLAIDFMVPENSALGDQVAQYAIDHMAERGISYVIWKQ
RFYAPFASIYGPAYTWNPMPDRGSITENHYDHVHVSFNA
>M5005_Spy0875 sortase
MVKKQKRRKIKSMSWARKLLIAVLLILGLALLFNKPIRNTLIARNSNKYQ
VTKVSKKQIKKNKEAKSTFDFQAVEPVSTESVLQAQMAAQQLPVIGGIAI
PELGINLPIFKGLGNTELIYGAGTMKEEQVMGGENNYSLASHHIFGITGS
SQMLFSPLERAQNGMSIYLTDKEKIYEYIIKDVFTVAPERVDVIDDTAGL
KEVTLVTCTDIEATERIIVKGELKTEYDFDKAPADVLKAFNHSYNQVST
>M5005_Spy0500 N-acetylmuramoyl-L-alanine amidase
MRRKIKPIVVLVFFILLAMVLIIGKRQANHAKQKEVEDAKSHIPIATSNP
GKAKTSTSETEDFILNPIVDVSGWQLPEEIDYDTLSRHISGAIVRVYGGS
QITAHNNAAFTTGIDKSFKTHIKEFQKRNVPVAVYSYALGRSTKEMKEEA
RAFYKNAAPYNPTYYWIDVEEATMKDMNKGVTAFREELKKLGAENVGLYI
GTYFMAEQDISTKGFDSVWIPTYGSDSGYYEAAPNTTLDYDLHQYTSQGY
LSGFNNALDLNQIAVTKDTKKTFEKLFGNSNN
>M5005_Spy0760 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase
MKMKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACDKDILKDLSKDYDI
VVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKG
KSERQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQM
IVDGARNAPKATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNT
EGILCPKCEHILQYRLNTYANLGDFVCLNCQFQRPTLDYQLTELTAITHQ
SSEFVIDGQNYKINVGGLYNIYNALAAVSVAEFFGVSPEKIKAGFNKSKA
VFGRQETFTVGDKSCTLILIKNPVGASQALEMIQLADYPFSLSVLLNANY
ADGIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVTGFDDTKIK
QAEKLEQIIETIEKQEAKHAYILATYTAMLEFRSLLADRHVVEKEMI
>M5005_Spy0240 undecaprenyl-phosphatealpha-N-acetylglucosaminephosphotransferase
MPTSGGLAIFMSFLVASLGLIPIASKGAMFFGQTYFSYILPVVIGATVIT
LTGFLDDLYELSPKLKMFGILIGAVIVWAFTDFKFDSFKIPFGGPLLVFG
PFLTLFLTVLWIVSITNAINLIDGLDGLVSGVSIISLVTMAIVSYFFLPQ
KDFFLTLTILVLISAIAGFFPYNYHPAMIYLGDTGALFIGFMIGVLSLQG
LKNSTAVAVVTPVIILGVPIMDTIVAIIRRSLSGQKFYEPDKMHLHHRLL
SMGFTHRGAVLVVYGITMLFSLISLLLNVSSRIGGVLLMLGLLFGLEVFI
EGLEIWGEKRTPLFNLLKFIGNSDYRQAMLLKWKEKKDLKH
>M5005_Spy0449 UDP-glucose 6-dehydrogenase
MKITVVGIGYVGLSIGLLLAKEHDVTFFDIDNKKIDLINKRQSPLKEAAI
NKLLCKAKNINATSSEELAYKDATFIILSLPTNLKFNKLDTSIIEISVSN
ILKINKKATIVIKSTVPIGFTEYLRNRFHYNDIIFSPEFLREGSTIHDQL
YPSRTIVGNESRNSQLFLDILTDISVEKDSPSLLVGSSEAEAIKLFSNAY
LAQKIAFFNELDTFAEMQNLDSKKIIEAMGYDQRIGNSHNNPSFGFGGYC
LPKDIKQLEYHFKEIPAPIITSISESNLLRKIHIAKMILNSSAKTIGIYR
INSKKDSDNCRESSTIDVAKLLKSSGKDVIIFEPLINQKKFLGCPLINDF
NEFIKYSDIIVANRIDDALRKCNSKVFTRDIFQYD
>M5005_Spy1502 D-alanyl-D-alanine carboxypeptidase
MKYNSLNYLVQLLIVIVFLGGLYLFIKPEESVTPTQLNKKEIQQKDIKKT
DRLRALPKVSVEDWELVLVNRDHITKEMSPELADINGISVDKRIEQATSD
FLAAAQAIDLQEHLISGYRSVDYQTELYQSYIKKEMANDPTLTQEAAEAL
VQTYSQPPGASEHHTGLAIDMSTVDTLNASDPSVAKAVQKIAPDYGFVLR
FPEGKKTSTGVDYEDWHYRYVGKASARYMAQHNLTLEEYIAALKEKR
>M5005_Spy0856 glycine betaine transport system permease protein
MPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALLSRSKRW
SDIMLQVTGVFQTIPSLALLGLFIPLMGIGTLPAVTALVIYAIFPILQNT
ITGLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVMII
GTATLASLIGAGGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLLQY
LEKASLRRIMISFGITLLALLASYTPMALSQFSKGKDTVVIAGKLGAEPD
ILINLYKELIEDQSDISVELKSNFGKTSFLYEALKSGDIDMYPEFTGTIT
SSLLRDKPPLSNDPKQVYEDAKKGIAKQDKLTLLKPFAYQNTYAVAMPEK
LAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGMQSQYGLQLSVAT
MEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPL
MKTSLLTKHPELKGILNQLAGKITEKEMQDMNYEVSVKGADANKVARDYL
LKTGLIQK
>M5005_Spy0609 phosphoglycerol transferase
MIKDTFLKTNWLNISHHIILLVFGFYFSFYSLAKELVSSTAQPVNYYAHL
LNVSFVGYIISLIGLSYYLSRQVSRQLFLKTSFIVISYLIVSYWVQITQH
LNDKRFDIWSLTKNQFYQFQALPSLLIILVMATLIKILVAYFAIEKDRFG
LLGYQGNTFSVALILAVVPINDIHLLKLISSRFSELVTAGNSQIALLKIS
GLLIVLLVIFATIIYVVLNALKHLKSNKPSFSVAATTSLFLALVFNYTFQ
YGVKGDEALLGYYVFPGATLFQIVAITLVALLAYVITNRYWPTTFFLLIL
GTIISVVNDLKESMRSEPLLVTDFVWLQELGLVTSFVKKSVIVEMVVGLA
ICIVVAWYLHGRVLAGKLFMSPVKRASAVLGLFIVSCSMLIPFSYEKEGK
ILSGLPIISALNNDNDINWLGFSTNARYKSLAYVWTRQVTKKIMEKPTNY
SQETIASIAQKYQKLAEDINKDRKNNIADQTVIYLLSESLSDPDRVSNVT
VSHDVLPNIKAIKNSTTAGLMQSDSYGGGTANMEFQTLTSLPFYNFSSSV
SVLYSEVFPKMAKPHTISEFYQGKNRIAMHPASANNFNRKTVYSNLGFSK
FLALSGSKDKFKNIENVGLLTSDKTVYNNILSLINPSESQFFSVITMQNH
IPWSSDYPEEIVAEGKNFTEEENHNLTSYARLLSFTDKETRAFLEKLTQI
NKPITVVFYGDHLPGLYPDSAFNKHIENKYLTDYFIWSNGTNEKKNHPLI
NSSDFTAALFEHTDSKVSPYYALLTEVLNKASVDKSPDSPEVKAIQNDLK
NIQYDVTIGKGYLLKHKTFFKISR
>M5005_Spy0869 antigen
MFRLLKRACSFLLLFVIYQSFVIHHNVQRVLAYKPMVEKTLAENDTKANV
DLVLAMIYTETKGGEADVMQSSESSSGQKNSITDSQASIEHGVNLLSHNL
ALAEEAGVDSWTAVQAYNFGTAYIDYIAEHGGQNTVDLATTYSKTVVAPS
LGNTSGQTYFYYHPLALISGGKLYKNGGNIYYSREVHFNLYLIELMSLF
>M5005_Spy1448 phage-related protein
MRTEKDIENYLKKKTKGLCLKFTSPGTIGVPDRIVVMNTGTFFVEVKAPG
KKPRPSQVAMHKKIKEAGQHVWVVDSYESVDMALKEMENWV
>M5005_Spy0610 glycosyltransferase
MKKLIIIPAYNESSNIVNTIRTIESDAPDFDYIIIDDCSTDNTLAICQKQ
GFNVISLPINLGIGGAVQTGYRYAQRCGYDVAVQVDGDGQHNPCYLEKMV
EVLVQSSVNMVIGSRFITKEGFQSSFARRIGIKYFTWLIALLTGKKITDA
TSGLRLIDRSLIERFANHYPDDYPEPETVVDVLVSHFKVKEIPVVMNERQ
GGVSSISLTKSVYYMIKVTLAILVVRLKGNR
>M5005_Spy1366 division specific D,D-transpeptidase/cell division protein ftsI
MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIINFMIIIG
TDQKFGVSLSEGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAI
LDKSFVSASDEKLYVQPSQYETVADILKKHLGMKKTDVIKQLKRKGLFQV
SFGPSGSGISYSTMSTIQKAMEDAKIKGIAFTTSPGRMYPNGTFASEFIG
LASLTEDKKTGVKSLVGKTGLEASFDKILSGQDGVITYQKDRNGTTLLGT
GKTVKKAIDGKDIYTTLSEPIQTFLETQMDVFQAKSNGQLASATLVNAKT
GEILATTQRPTYNADTLKGLENTNYKWYSALHQGNFEPGSTMKVMTLAAA
IDDKVFNPNETFSNANGLTIADATIQDWSINEGISTGQYMNYAQGFAFSS
NVGMTKLEQKMGNAKWMNYLTKFRFGFPTRFGLKDEDAGIFPSDNIVTQA
MSAFGQGISVTQIQMLRAFTAISNNGEMLEPQFISQIYDPNTASFRTANK
EIVGKPVSKKAASETRQYMIGVGTDPEFGTLYSKTFGPIIKVGDLPVAVK
SGTAQIGSEDGSGYQDGGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHFG
PLFWQDVVNPVLEEAYLMQDTLTKPVVSDANRQTTYKLPNFVGKNPGETS
SELRRNLVQPVVLGTGSKIKKVSHQPGQTLTENQQVLILSDRFVEVPDMY
GWTKSNVKTFAKWTGIDISFKGTDSGRVMKQSVDVGKSLKKIKKMTITLG
D
>M5005_Spy0114 sortase
MECYRDRQLLSTYHKQVTQKKPSEMEEVWQKAKAYNARLGIQPVPDAFSF
RDGIHDKNYESLLQIENNDIMGYVEVPSIKVTLPIYHYTTDEVLTKGAGH
LFGSALPVGGDGTHTVISAHRGLPSAEMFTNLNLVKKGDTFYFRVLNKVL
AYKVDQILTVEPDQVTSLSGVMGKDYATLVTCTPYGVNTKRLLVRGHRIA
YHYKKYQQAKKAMKLVDKSRMWAEVVCAAFGVVIAIILVFMYSRVSAKKS
K
>M5005_Spy1532 acpS, alanine racemase
MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAYGHGAVQ
VSKALLPQVDGYCVSNLDEALQLRQAGIDKEILILGVLLPNELELAVANA
ITVTIASLDWIALARLEKKECQGLKVHVKVDSGMGRIGLRSSKEVNLLID
SLKELGADVEGIFTHFATADEADDTKFNQQLQFFKKLIAGLEDKPRLVHA
SNSATSIWHSDTIFNAVRLGIVSYGLNPSGSDLSLPFPLQEALSLESSLV
HVKMISAGDTVGYGATYTAKKSEYVGTVPIGYADGWTRNMQGFSVLVDGQ
FCEIIGRVSMDQLTIRLPKAYPLGTKVTLIGSNQQKNISTTDIANYRNTI
NYEVLCLLSDRIPRIY
>M5005_Spy0545 agaS, galactosamine-6-phosphate deaminase (isomerizing)
MFTKTQEALEALGAAITTKEIKQEPRLWQETMTFFEETRDSLDSFLKRVC
NSANRNNVHVIFTGAGTSEYIGNTICPYLKKVGNRQRYLFESVASTDLVA
APDYYLVEEETVLLVSFARSGNSPESVAAVNLVNQLVPNSYHLTITCAKD
GELAKKAQQDERSYLYLMPEDANDAGFAMTGSFTCMMLAALLIFDDANSI
AQKEAYVTDMILAGQAVIDQERRLQELADLGFERLVYLGSAGLAKLTQEA
QLKMLELTAGQVATLYESSMGFRHGPKSFINDRTLVIGFVNNDAYVRQYD
LDMLEEIQADGIALKILALLQGGDINFSEDQFRLDTRHLLPDAYLAFPMI
LVAQTLALLTAVTLGNSPDTPSATGTVNRVVKGVTIHPYPTSSRQCNKA
>M5005_Spy0632 capA, capsule biosynthesis protein
MILLKSLYKGFFAAMKEENFEARCYNREKGGCVLIKTMQYKKTMATVVAL
IVALLLFGLIYDLLGVQKNELAAQKSAQPKVKTARVVANGDILIHDILYM
SARKADDTYDFTPYFEYVKDWISGADLAIGDYEGTISPDYPLAGYPLFNA
PEEIAGALKNTGYDVVDLAHNHILDSQLDGALNTKKVFHQLGIDSIGIYD
KDRSKESFLIKNVNGIKIAILGYSYGYNGMEATLSQEDYEKHMSDLDEAK
IKKELQLAEKKADVTIVMPQMGTEYALEPTAEQKELYHKMIDWGADVVLG
GHPHVIEPSETVIKGRQKKFIIYSMGNFISNQRLETVDDIWTERGLLMDL
TFEKKDNKTKIKTVEAHPTMVLAKGKGIVGKEGFELYNYRTMVLEDFIKG
GKYHDKIDEETKAKVALAYQEINDLVNLKW
>M5005_Spy0734 cpsFO, glucose-1-phosphate thymidylyltransferase
MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLAGIKDVL
IISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDD
RVALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDE
NMNAISIEEKPEVPKSHFAVTGLYFYDNDVVEIAKNIKPSARGELEITDV
NKAYLERGDLSVELMGRGFAWLDTGTHESLLEAAQYIETVQRLQNAQVAN
LEEIAYRMGYISKEDVHKLAQSLKKNEYGQYLLRLIGEA
>M5005_Spy0735 cpsFP, dTDP-4-dehydrorhamnose 3,5-epimerase
MTETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEKMLPIGF
PERFFEEGKLQNNVSFSRQHVLRGLHAEPWDKYISVADDGKVLGAWVDLR
EGETFGNVYQTVIDASKGMFVPRGVANGFQVLSETVSYSYLVNDYWALDL
KPKYAFVNYADPSLGITWENLAAAEVSEADKNHPLLSDVKPLKPKDL
>M5005_Spy0736 cpsFQ, dTDP-glucose 4,6-dehydratase
MYKNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNRANIEAIL
GDRVELVVGDIADAELVDKLAAKTDVIVHYAAESHNDNSLEDPSPFIHTN
FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGQGEGPGEKFTAE
TKYNPSSPYSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFI
PRQITNILAGIKPKLYGEGKNVRDWIHTNDHSTGVWAILTKGRIGETYLI
GADGEKNNKEVLELILEKMGQPKDAYDHVTDRAGHDLRYAIDSTKLREEL
GWEPQFTNFSEGLEETIKWYTENETWWKAEKDAVEAKYAKTQEVIK
>M5005_Spy0817 dacA1, D-alanyl-D-alanine carboxypeptidase
MSLFKLLKVCATILPSKFLRIFVIIVTMKDIMIKRWVILFFMVLTCSGFG
KTVLAADFQVGAEHAIVVEADSGRVLYEKDAKTPDAIASLTKLVTAYLVL
DKVKSGQLQLSDQVNLSDYAFELTKDRSLSNVPFDKKTYSVQDLLTATLV
ASSNSAAIALAEKVAGSELHFVNQMREQLSHWGITSGKILNASGLPNEVL
KDHRYPGSALEEENMLSAQDVAIVTMHLLEDFPEILEITKQTEVDFAGNS
IKSFNQLLPGMAKGRAGVDGLKTGTTDLAGHCLVVTSIENGMRLITVILN
ADGSDKNQNTRFEQANRLLDYVARTYCRRKILKKGSLVSERSLPIQDGQV
KELPISVAEDVTIILQQGEQVPKPKQFMISETSLLAPITKGEVVAYLTSP
RITDQSVRYLKEPKRIPLKASQSLKKASDLQLWWRDFLEKRR
>M5005_Spy0248 dacA2, D-alanyl-D-alanine carboxypeptidase
MIKRLISLVVIALFFAASTVSGEEYSVTAKHAIAVDLESGKVLYEKDAKE
VVPVASVSKLLTTYLVYKEVSKGKLNWDSPVTISNYPYELTTNYTISNVP
LDKRKYTVKELLSALVVNNANSPAIALAEKIGGTEPKFVDKMKKQLRQWG
ISDAKVVNSTGLTNHFLGANTYPNTEPDDENCFCATDLAIIARHLLLEFP
EVLKLSSKSSTIFAGQTIYSYNYMLKGMPCYREGVDGLFVGYSKKAGASF
VATSVENQMRVITVVLNADQSHEDDLAIFKTTNQLLQYLLINFQKVQLIE
NNKPVKTLYVLDSPKKTVKLVAQNSLFFIKPIHTKTKNTVHITKKSSTMI
APLSKGQVLGRATLQDKHLIGQGYLDTPPSINLILQKNISKSFFLKVWWN
RFVRYVNTSL
>M5005_Spy1158 ddlA, D-alanine--D-alanine ligase
MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFITQMGQFI
KTQQFSEKPSESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGED
GSIQGFLEVLRMPYIGTNVMSSSIAMDKITTKRVLESIGIPQVAYTVYID
GQDLEACLVETLARLTFPIFVKPANMGSSVGISKAQTKVELRKAIQLALT
YDSRVLIEQGVVAREIEVGLLGNDKVKSTLPGEVIKDVDFYDYQAKYVDN
KITMAIPADVDQSIVTEMRSYAEVAFKALGGCGLSRCDFFLTQDGQVYLN
ELNTMPGFTQWSMYPLLWENMGLAYPDLIEELVTLAQEMFDQRESHLI
>M5005_Spy0389 dgk, diacylglycerol kinase
MALHDNNTTKRKWKNRTITSSLEFALTGVFTAFKEERNLRSHLLSACLAC
VAGLFFSISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAK
NAKDMAAGAVLMISGYAVLTGLIIFIPKIWNIFVH
>M5005_Spy1251 divIB, cell division protein
MAKDKEKQSDDKLVLTEWQKRNIEFLKKKKQQAEEEKKLKEKLLSDKKAQ
QQAQNASEAVELKTDEKTDSQEIESETTSKPKKTKKVRQPKEKSATQIAF
QKSLPVLLGALLLMAVSIFMITPYSKKKEFSVRGNHQTNLDELIKASKVK
ASDYWLTLLTSPGQYERPILRTIPWVKSVHLSYQFPNHFLFNVIEFEIIA
YAQVENGFQPILENGKRVDKVRASELPKSFLILNLKDEKAIQQLVKQLTT
LPKKLVKNIKSVSLANSKTTADLLLIEMHDGNVVRVPQSQLTLKLPYYQK
LKKNLENDSIVDMEVGIYTTTQEIENQPEVPLTPEQNAADKEGDKPGEHQ
EQTDNDSETPANQSSPQQTPPSPETVLEQAHG
>M5005_Spy1070 dltD, protein precursor
MLKRLWLILGPLLIAFVLVVITIFSFPTQLDHSIAQEKANAVAITDSSFK
NGLIKRQALSDETCRFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIG
KRGSASLSHYYGMQQITNEMQKKKAIFVVSPQWFTAQGINPSAVQMYLSN
TQVIEFLLKARTDKESQFAAKRLLELNPGVSKSNLLKKVSKGKSLSRLDR
AILKCQHQVALREESLFSFLGKSTNYEKRILPRVKGLPKVFSYKQLNALA
TKRGQLATTNNRFGIKNTFYRKRIAPKYNLYKNFQVNYSYLASPEYNDFQ
LLLSEFAKRKTDVLFVITPVNKAWADYTGLNQDKYQAAVRKIKFQLKSQG
FHRIADFSKDGGESYFMQDTIHLGWNGWLAFDKKVQPFLETKQPVPNYKM
NPYFYSKIWANRKDLQ
>M5005_Spy0362 gcaD, glucosamine-1-phosphateacetyltransferase/UDP-N-a cetylglucosaminepyrophosphorylase
MTNYAIILAAGKGTRMTSDLPKVLHKVSGLTMLEHVFRSVKAISPEKSVT
VIGHKSEMVRAVLADQSAFVHQTEQLGTGHAVMMAETQLEGLEGHTLVIA
GDTPLITGESLKSLIDFHVNHKNVATILTATAQDPFGYGRIVRNKDGEVI
KIVEQKDANEYEQQLKEINTGTYVFDNKRLFEALKCITTNNAQGEYYLTD
VVAIFRANKEKVGAYILRDFNESLGVNDRVALAIAETVMRQRITQKHMVN
GVTFQNPETVYIESDVEIAPDVLIEGNVTLKGRTHIGSGTVLTNGTYIVD
SEIGDNCVVTNSMIESSVLAAGVTVGPYAHLRPGTTLDREVHIGNFVEVK
GSHIGEKTKAGHLTYIGNAQVGSSVNVGAGTITVNYDGQNKYETVIGDHA
FIGSNSTLIAPLEVGDHALTAAGSTISKTVPIDSIAIGRSRQVTKEGYAK
RLAHHPSRSK
>M5005_Spy0278 gidB, glucose inhibited division protein B
MTPQDFYRTLEEDGFSLSSKQKEQFDTYFKSLVEWNTKINLTAITEENEV
YLKHFYDSIAPILQGFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTII
DSLNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDVVTARAV
ARMQVLSELTIPFLKIGGKLIALKAQAADQELEEAKNALCLLFGKVIKNH
SYQLPNGDSRFITIVEKKKETPNKYPRKAGLPNKKPL
>M5005_Spy0986 glmS, glucosamine--fructose-6-phosphate aminotransferase (isomerizing)
MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNLIKSVGR
IADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNG
VIENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKSL
SIIEGSYAFALMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRE
TSEFMEIHDKELVILTKDKVTVTDYDGKELIRDSYTAELDLSDIGKGTYP
FYMLKEIDEQPTVMRQLISTYADETGNVQVDPAIITSIQEADRLYILAAG
TSYHAGFATKNMLEQLTDTPVELGVASEWGYHMPLLSKKPMFILLSQSGE
TADSRQVLVKANAMGIPSLTVTNVPGSTLSREATYTMLIHAGPEIAVAST
KAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKD
LAAEKVQALLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGE
LKHGTISLIEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEG
LDREGDDIIVNKVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKA
VTVE
>M5005_Spy0303 glr, glutamate racemase
MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGPRPKKQI
KEYTWELVNFLLTQNVKMIVFACNTATAVAWEEVKAALDIPVLGVVLPGA
SAAIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSIQVRSLACPKFVPI
VESNEMCSSIAKKIVYDSLAPLVGKIDTLVLGCTHYPLLRPIIQNVMGPS
VKLIDSGAECVRDISVLLNYFDINGNYHQKAVEHRFFTTANPEIFQEIAS
IWLKQKINVEHVTL
>M5005_Spy1851 hasA, hyaluronan synthase
MPIFKKTLIILSFIFLISILIYLNMYLFGTSTVGIYGVILITYLVIKLGL
SFLYEPFKGKPHDYKVAAVIPSYNEDAESLLETLKSVLAQTYPLSEIYIV
DDGSSNTDAIQLIEEYVNREVDICRNVIVHRSLVNKGKRHAQAWAFERSD
ADVFLTVDSDTYIYPNALEELLKSFNDETVYAATGHLNARNRQTNLLTRL
TDIRYDNAFGVERAAQSLTGNILVCSGPLSIYRREVIIPNLERYKNQTFL
GLPVSIGDDRCLTNYAIDLGRTVYQSTARCDTDVPFQLKSYLKQQNRWNK
SFFRESIISVKKILSNPIVALWTIFEVVMFMMLIVAIGNLLFNQAIQLDL
IKLFAFLSIIFIVALCRNVHYMIKHPASFLLSPLYGILHLFVLQPLKLYS
LCTIKNTEWGTRKKVTIFK
>M5005_Spy1852 hasB, UDP-glucose 6-dehydrogenase
MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSPIQDEYI
EYYLKSKQLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETV
IKEVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALY
DNLYPSRIIVSCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEA
EAVKLFANTYLALRVAYFNELDTYAESRKLNSHMIIQGISYDDRIGMHYN
NPSFGYGGYCLPKDTKQLLANYNNIPQTLIEAIVSSNNVRKSYIAKQIIN
VLEERESPVKVVGVYRLIMKSNSDNFRESAIKDVIDILKSKDIKIIIYEP
MLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNKVYSRDIFN
RD
>M5005_Spy1853 hasC, UTP--glucose-1-phosphate uridylyltransferase
MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGI
EEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKNELLKLVDETTAINLHF
IRQSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLME
DYDKTHASTIAVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPED
APSDLAIIGRYLLTPEIFGILERQTPGAGNEVQLTDAIDTLNKTQRVFAR
EFKGNRYDVGDKFGFMKTSIDYALEHPQVKEDLKNYIIKLGKALEKSKVP
THSK
>M5005_Spy0192 hasC.2, UTP--glucose-1-phosphate uridylyltransferase
MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGI
EEILIVTGKSKRSIEDHFDSNFELEYNLQAKGKIELLKLVDETTSINLHF
IRQSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQLID
DYEETHAATIAVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQPQD
APSDLAIIGRYLLTPEIFSILEKQEPGAGNEVQLTDAIDTLNKTQRVFAR
EFKGKRYDVGDKFGFMKTSLDYALKHPQVKDDLKAYIIQLGKALEKTKP
>M5005_Spy0776 lepA, GTP-binding protein
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLL
DSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRS
LAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPE
RVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPL
QALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFT
PKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQM
NPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCG
FLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFP
DPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVN
VIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGD
KVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARS
DIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLS
VLSMDDDTKK
>M5005_Spy0485 lgt, prolipoprotein diacylglyceryl transferase
MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSDAIFDFI
LIAFPLAIVGARIYYVIFEWSYYVKHLDEIIAIWNGGIAIYGGLITGALV
LLAYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNY
LPSFIQKQMFIEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIF
AFYLIWYGSGRLVIEGMRTDSLMFLGIRISQYVSALLIIIGLIFVIKRRR
QKGISYYQE
>M5005_Spy0637 lsp, lipoprotein signal peptidase
MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLTYLQNNG
AAFSILQDQQWFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGI
GNFIDRLRLAYVIDMIHLDFVDFAIFNVADSYLTVGVILLLICLWKEEDY
GN
>M5005_Spy1368 mraW, S-adenosyl-methyltransferase
MKSFSLTFSFLNLLKYGTIKVMTKEFHHVTVLLHETVDMLDIKPDGIYVD
ATLGGSGHSAYLLSKLGEEGHLYCFDQDQKAIDNAQVTLKSYIDKGQVTF
IKDNFRHLKARLTALGVDEIDGILYDLGVSSPQLDERERGFSYKQDAPLD
MRMDRQSLLTAYEVVNTYPFNDLVKIFFKYGEDKFSKQIARKIEQARAIK
PIETTTELAELIKAAKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESI
QDAMELLALDGRISVITFHSLEDRLTKQLFKEASTVDVPKGLPLIPEDMK
PKFELVSRKPILPSHSELTANKRAHSAKLRVAKKIRK
>M5005_Spy0598 mscL, large-conductance mechanosensitive channel
MVKELKAFLFRGNIIELAVAVIIGGAFGAIVTSFVNDIITPLILNPALKA
ANVENITQLSWNGVKYGSFLGAVINFLIIGTSLFFVVKAAEKAMPKKEKE
AAAPTQEELLTEIRDLLAQK
>M5005_Spy0584 murA, UDP-N-acetylglucosamine1-carboxyvinyltransferase
MNNVVRGLDIRVDFNEAANEITVDASGHILDEAPYEYVSQMRASIVVLGP
ILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITAQADR
LQGAMIYMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLAQFLNK
MGARIRGAGTETLTITGVTHLRGVEHDVVQDRIEAGTFMVAAAMTSGNVL
IRDAVWEHNRPLISKLMEMGVSVTEEEYGIRVQANTPKLKPVTVKTLPHP
GFPTDMQAQFTALMAVVNGESTMVETVFENRFQHLEEMRRMGLQSEILRE
TAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTIVNNLVHLDRGYY
QFHEKLAKLGATISRSSEV
>M5005_Spy0825 murB, UDP-N-acetylenolpyruvoylglucosamine reductase
MITELHGIDIRENEPLKHYTYTKVGGPADFLAFPRNHYELSRIVAYANKE
NMPWLVLGNASNLIVRDGGIRGFVIMFDKLNAVHLNGYTLEAEAGANLIE
TTKIAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEISHIFLSAKVLTP
SGEIKTISARDMAFGYRHSAIQETGDIVISAKFALKPGNYDTISQEMNRL
NHLRQLKQPLEFPSCGSVFKRPPGHFAGQLIMEANLKGHRIGGVEVSEKH
TGFMINVADGTAKDYEDLIAYVIETVENHSGVRLEPEVRIIGENL
>M5005_Spy0290 murC, UDP-N-acetylmuramate--alanine ligase
MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGLEQAGIT
ILPFSEDNITPDMELIVGNAFRENNKEVAYALRHQIPFKRYHDFLGDFMK
SFISFAVAGAHGKTSTTGLLSHVLKNITDTSYLIGDGTGRGSANAQYFVF
ESDEYERHFMPYHPEYSIITNIDFDHPDYFTGIADVRNAFNDYAKQVKKA
LFVYGEDDELKKIEAPAPIYYYGFEEGNDFIAYDITRTTNGSDFKVKHQG
EVIGQFHVPAYGKHNILNATAVIANLFVAGIDMALVADHLKTFSGVKRRF
TEKIINDTIIIDDFAHHPTEIVATIDAARQKYPSKEIVAIFQPHTFTRTI
ALLEDFACALNEADSVYLAQIYGSAREVDKGEVKVEDLAAKIIKPSQVVT
VENVSPLLDHDNAVYVFMGAGDIQLYEHSFEELLANLTKNNQ
>M5005_Spy1253 murD, UDP-N-acetylmuramoylalanine--D-glutamateligase
MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFDQNPAAQ
ALLEEGIKVICGSHPVELLDENFEYMVKNPGIPYDNPMVKRALAKEIPIL
TEVELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYP
ASKVVQKAIAGDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSF
EDYVAAKWMIQAQMTESDYLILNANQEISATLAKTTKATVIPFSTQKVVD
GAYLKDGILYFKEQAIIAATDLGVPGSHNIENALATIAVAKLSGIADDII
AQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNILATQKALSGFDNSRLI
LIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKAEVSYLEAR
NVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRG
DA
>M5005_Spy0325 murE, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--lysineligase
MITIEQLLDILKKDHNFREVLDADGYHYHYQGFSFERLSYDSRQVDGKTL
FFAKGATFKADYLKEAITNGLQLYISEVDYELGIPVVLVTDIKKAMSLIA
MAFYGNPQEKLKLLAFTGTKGKTTAAYFAYHMLKESYKPAMFSTMNTTLD
GKTFFKSQLTTPESLDLFAMMAECVTNGMTHLIMEVSSQAYLVDRVYGLT
FDVGVFLNISPDHIGPIEHPTFEDYFYHKRLLMENSRAVVINSGMDHFSF
LADQVADQEHVFYGPLSDNQITTSQAFSFEAKGQLAGHYDIQLIGHFNQE
NAMAAGLACLRLGASLADIQKGIAKTRVPGRMEVLTMTNHAKVFVDYAHN
GDSLEKLLSVVEEHQTGKLMLILGAPGNKGESRRADFGRVIHQHPNLTVI
LTADDPNFEDPEDISKEIASHIARPVEIISDREQAIQKAMSLCQGAKDAV
IIAGKGADAYQIVKGQQVAYAGDLAIAKHYL
>M5005_Spy1157 murF, UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-- D- alanyl-D-alanine ligase
MKLTLHEVAKIVDAQNNVSDLDDVPLHHIEFDSRKITKGDLFLPLKGQRD
GHEFIDLAFQNGAVATFSEKELPGKPHLLVEDCLKAFQKLAHYYIDKMRV
DVIAVTGSNGKTSTKDMIGAVLSTTYKTYKTQGNYNNEIGLPYTVLHMPD
DTEKIVLEMGQDHMGDIRLLSEIARPRIAVLTLVGEAHLEYFGSRDKIAQ
GKMQIVDGMNSDGILIAPGDPIIDPYLPENQMVIRFGNQQEIDVTGIQED
KDSLTFTTNVLATPVSLPLPGKYNATNAMVAAYVGKLLAVTDEDIIAALQ
TVTLTGNRTEWKKAANGADILSDVYNANPTAMRLILETFANIAKNPGGKK
IAVLADMKELGKDSVILHSQLIDSLTSGNIDQLVFYGDHIKELARLASQV
YPAEQVHYFLKTEQEDQFEAMAQYVQNILNPFDQILLKGSHSMSLEKLVD
RLVTDKNCDSYQP
>M5005_Spy1252 murG, UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
MPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEHTEIEKS
GLDVTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKLRPQALFS
KGGFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQE
DQLSKVKHLGAVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAG
AHVFNQFISDHPELKQRYNIINITGDPHLNELSSHLYRVDYVTDLYQPLM
AMADLVVTRGGSNTLFELLAMAKLHLIVPLGKEASRGDQLENATYFEKRG
YAKQLQEPDLTLHNFDQAMADLFEHQADYEATMLATKEIQSPDFFYDLLR
ADISSAIKEK
>M5005_Spy1107 murZ, UDP-N-acetylglucosamine 1-carboxyvinyl transferase
MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDV
DSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGS
LLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNG
QKIHGAHIYMDTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLL
NNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTYIALAAAIGKG
VKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPY
PGFATDLQQPLTPLLLKADGRGTIIDTIYEKRINHVPELMRMGADISVIG
GQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITNIEFILRGY
ASIIAKLTALGADIQLIED
>M5005_Spy0217 nanH, N-acetylneuraminate lyase
MTDLTKYQGIIPAFYACYDDQGNISPERVRALTQYYIDKGVQGLYINGSS
GECIYQSVFDRQLVLENVMAVAKGKLTIINHVACNNTKDSIELAAHSERL
GVDAIAAIPPIYFRLPEYAVADYWNAISSAAPHTDFIIYNIPQLAGVALT
PSLYKTMLANKRVIGVKNSSMPVQDIQTFCAIGGDDHIVFNGPDEQFLGG
RLMGAAAGIGGTYGAMPELFLRLNQLIADKDLEKAKALQYTINEIIGVLV
SAHGNMYGVIKEVLRINEGLDIGSVRSPLAELVEEDRVICQRAAALINQA
KETF
>M5005_Spy1355 pbp1A, multimodular transpeptidase-transglycosylase
MITIKNPKILKWLKYVLSAILSLIILVIIIGGLLFTFYISSAPKLSEAQL
KSTNSSLVYDGNNNLIADLGSEKRENVTADSIPINLVNAITSIEDKRFFN
HRGVDLYRIFGAAFHNLTSQTTQGGSTLDQQLIKLAYFSTNESDQTLKRK
AQEVWLALQMERKYTKQEILTFYINKVYMGNGNYGMLTAAKSYYGKDLKD
LSYAQLALLAGIPQAPSQYDPYLHPEAAQNRRNVVLQQMYMEKHLTKAEY
ETAIATPVAEGLQSLQQRSTYPKYMDNYLKQVIEEVKKETNKDIFTAGLK
VYTNIIPDAQQTLYNIYHSGDYVYYPDQDFQVASTIVDVTNGHVIAQLGG
RNQDENVSFGTNQAVLTDRDWGSTMKPITAYAPAIESGVYTSTAQSTNDS
VYYWPGTTTQLFNWDLRYNGWMTIQAAIMLSRNVPAVRALEAAGLDYARS
FLSSLGINYPEMHYSNAISSNNSSSDKKYGASSEKMAAAYAAFANGGIYH
KPRYVNKVEFSDGTSKTFDEKGKRAMKETTAYMMTDMLKTVLTYGTGTAA
AIPGVAQAGKTGTSNYTDEELAKIGEKYGLYPDYVGTLAPDENFVGFTKR
YAMAVWTGYKNRLTPVYGSSLEIASDVYRSMMTYLTNGYSEDWTMPNGLY
RSGGFLYLSGTYASNTDYTNSVYNNLYSNNTTTASSQTTSDDTSSSNDTS
NSTNTDNNGSHPSTDDKKTTH
>M5005_Spy0082 pbp1b, multimodular transpeptidase-transglycosylase PBP 1B
MRYFMVKWNTKQKRISHQRLGLLDLGPVLLRTLRLLSNFFYIVIFLFGMM
GFGMAFGYLASQIESVKVPSKESLVKQVESLTMISQMNYSDNSLISTLDT
DLLRTPVANDAISENIKKAIVSTEDEHFQEHKGIVPKAVFRATLASVLGF
GEASGGSTLTQQLVKQQVLGDDPTFKRKSKEIVYALALERYMSKDNILCD
YLNVSPFGRNNKGQNIAGVEEAARGIFGVSAKDLTVPQAAFLAGLPQSPI
VYSPYLSTGQLKSEKDMAYGIKRQQNVLFNMYRTGVLSKKEYEDYKAYPI
QKDFIQPGSAIVNNHDYLYYTVLADAKKAMYSYLIKRDKVSSRDLKNDET
KAAYEERALTELQQGGYTITTTINKPIYNAMQTAAAQFGGLLDDGTGTVQ
MGNVLTDNATGAVLGFVGGRDYALNQNNHAFNTVRSPGSSIKPIIAYGPA
IDQGLMGSASVLSNYPTTYSSGQKIMHADSEGTAMMPLQEALNTSWNIPA
FWTQKLLREKGVDVENYMTKMGYKIADYSIESLPLGGGIEVSVAQQTNAY
QMLSNNGLYQKQYIVDKITASDGTVVYKHENKPIRIFSAATATILQELLR
GPITSGATTTFKNRLAAINPWLANADWIGKTGTTENYTDVWLVLSTPKVT
LGGWAGHDDNTSLAPLTGYNNNSNYLAYLANAINQADPNVIGVGQRFNLD
PGVIKANVLKSTGLQPGTVNVNGHTFSVGGEMTTSLWSQKGPGAMTYRFA
IGGTDADYQKAWGNFGFRKN
>M5005_Spy1753 pbp2A, multimodular transpeptidase-transglycosylase
MRFLELLQKKFFPKAYQEKQFLMHQKTRLTPQHNQKQYSPNANHLDSSAT
KNSEQDPATALQRSRAYEGSPKSRPAWLQKLEAVLPSPQRPIRRFWRRYH
IGKLLMILIGTLVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDHKGEYA
GSLSGQKGSYVELNAISDDLENAVIATEDRTFYSNSGINLKRFLLAVVTA
GRFGGGSTITQQLAKNAYLSQDQTIKRKAREFFLALELTKKYSKKDILTM
YLNNSYFGNGVWGVEDASQKYFGTTAANLTLDEAATLAGMLKGPEIYNPY
HSLKNATHRRDTVLGAMVDAKKITQTKAQQARAVGLKNRLADTYVGKTDD
YKYPSYFDAVISEAIATYGLSEKDIVNNGYKVYTELDQNYQTGMQTTFNN
DELFPVSAYDGSSAQAASVALDPKTGGVRGLIGRVNSSENPTFRSFNYAT
QAKRSPASTIKPLVVYAPAVASGWSIEKELPNTVQDFDGYQPHNYGNYES
EDVPMYQALANSYNIPAVSTLNDIGIDKAFTYGKTFGLDMSSAKKELGVA
LGGSVTTNPLEMAQAYAAFANNGVIHPAHLINRIENARGEVLKTFTDKAK
RVVSQSVADKMTAMMLGTFSNGTAVNANVYGYTLAGKTGTTETNFNPDLA
GDQWVIGYTPDVVISQWVGFNQTDENHYLTDSSAGTASAIFSTQASYILP
YTKGSQFHVDNAYAQNGISAVYGVNETGNQSGVDTQSIIDGLRKSAQEAS
QSLSKAVDQSGLRDKAQSIWKEIVDYFR
>M5005_Spy0603 rgpAc, alpha-(1,2)-rhamnosyltransferase
MQDVFIIGSRGLPAKYGGFETFVEELISHQSSKNIRYHVACLSDTKHKVH
FDYKGADCFYLNPPKLGPARVIAYDMMAITYALSYSDQHQIQNPIFYVLG
NTVGAFIAPFVKQIHNRGGRFFINPDGLEWKRSKWSRPVQAYLKFSEKQM
TRQADLVISDNIGIDRYLKQVYPWSKTCFIAYGTQTQPSRLATADSKVRA
YFQTFDIREKDYYLILGRFVPENNYETAIKEFMASSTKRDLVIICNHEGN
AYFKQLLAETECDKDPRIKFVGTLYDKELLAYIREQAYAYIHGHEVGGTN
PGLLEALAHTNLNLVLGVDFNQSVAKSAALYWTKQKGQLAELINQVDAGF
DSDHLGKEAKAIIQEHYTWEKIVGEYEALFLNEH
>M5005_Spy0604 rgpBc, alpha-L-Rha alpha-1,3-L-rhamnosyltransferase
MNINILLSTYNGERFLAEQIQSIQRQTVNDWTLLIRDDGSTDGTQDIIRT
FVKEDKRIQWINEGQTENLGVIKNFYTLLKHQKADVYFFSDQDDIWLDNK
LEVTLLEAQKHEMTAPLLVYTDLKVVTQHLAVCHDSMIKTQSGHANTSLL
QELTENTVTGGTMMITHALAEEWTTCDGLLMHDWYLALLASAIGKLVYLD
IPTELYRQHDANVLGARTWSKRMKNWLTPHHLVNKYWWLITSSQKQAQLL
LDLPLKPNDHELVTAYVSLLDMPFTKRLATLKRYGFRKNRIFHTFIFRSL
VVTLFGYRRK
>M5005_Spy0605 rgpCc, polysaccharide export ABC transporter permease protein
MNFLTKKNRILLREMVKTDFKLRYQGSAIGYLWSILKPLMMFTIMYLVFI
RFLRLGGNVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFS
KHIIVFSAVLGALINFLINLVVVLIFALINGVTISGYAYLSLFLFIELVV
LVLGIALLLSNVFVYYRDLAQVWEVLLQAGMYATPIIYPITFVLDSHPLA
AKLLMLNPVAQMIQDFRYLLIDRANVTIWQMSTNWFYIVIPYLVPFVILF
IGIFVFKKNADRFAEII
>M5005_Spy0606 rgpDc, polysaccharide export ATP-binding protein
MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQHVLKDI
NFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVDGKMVSFIEL
GVGFNPELTGRENVYMNGAMLGFTKDEVDDMYNDIVDFAELHHFMNQKLK
NYSSGMQVRLAFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKDS
GKTTILVTHDMGAVKKYCNRAVLIEDGLVKAYGEPFDVANQYSVDNTETA
EDAMNAEKISVSDIAKDLKVSLISNPRITPNDTITFEVSYEVLKDDFTYI
AFSLTDIDRNIWVYNDNSLDYPTQGIGRKCISYQCQLSQLNDIKLKLEVT
VRDKNGQMLLFSTAEQSPQIVIQRNDIDQDDLSALDSASGLYQRNGKWVF
H
>M5005_Spy0607 rgpEc, glycosyltransferase
MYKVSIICTNYNKAPWISDALDSFLSQVTDFEVEIIVIDDASTDDSREIL
KSYQKKSSGKIKLLFNETNIGITKTWIKACLYAKGKYIARCDGDDYWTDS
FKLQKQVDVLEASKRSRWCNTDFDFVNSQGDLLYANAFSSGHTPLTDTYE
KVLALKGMTMASTWLVDADLMRQVNQKINVDTPDDTFDIQLELFQLTQLT
YIKDSTTIYRMTTDSDSRPTDTPKMIYRIQKLLDTQLNYLKKYNQVDTKE
VSELLLQQDAKQEIRIHELSCFIQELQQTIVDKTKQQETREVELQNVIEE
QKNQLSELRQQYHAIINSRQWKYTSKLIAFIRRKK
>M5005_Spy0608 rgpFc, alpha-L-Rhaalpha-1,2-L-rhamnosyltransferase/alph a-L-Rhaalpha-1,3-L-rhamnosyltransferase
MNRILLYVHFNKYNKISAHVYYQLEQMRSLFSKIVFISNSKVSHEDLKRL
KNHCLIDEFLQRKNKGFDFSAWHDGLIIMGFDKLEEFDSLTIMNDTCFGP
IWEMAPYFENFEEKETVDFWGITNNRGTKAFKEHVQSYFMTFKNQVIQNK
VFQQFWQSIIEYENVQEVIQHYETQLTSILLNEGFSYQTVFDTRKAESSF
MPHPDFSYYNPTAILKHHVPFIKVKAIDANQHIAPYLLNLIRETTNYPID
LIVSHMSQISLPDTKYLLSQKYLNCQRLAKQTCQKVAVHLHVFYVDLLDE
FLTAFENWNFHYDLFITTDSDIKRKEIKEILQRKGKTADIRVTGNRGRDI
YPMLLLKDKLSQYDYIGHFHTKKSKEADFWAGESWRKELIDMLVKPADSI
LSAFETDDIGIIIADIPSFFRFNKIVNAWNEHLIAQEMMSLWRKMDVKKQ
IDFQAMDTFVMSYGTFVWFKYDALKSLFDLELTQNDIPSEPLPQNSILHA
IERLLVYIAWGDSYDFRIVKNPYELTPFIDNKLLNLREDEGAHTYVNFNQ
MGGIKGALKYIIVGPAKAMKYIFLRLMEKLK
>M5005_Spy0602 rmlD, dTDP-4-dehydrorhamnose reductase
MILITGSNGQLGTELRYLLDERGVDYVAVDVAEMDITNEDKVEAVFAQVK
PTLVYHCAAYTAVDAAEDEGKALNEAINVTGSENIAKACGKYGATLVYIS
TDYVFDGNKPVGQEWVETDHPDPKTEYGRTKRLGELAVERYAEHFYIIRT
AWVFGNYGKNFVFTMEQLAENHSRLTVVNDQHGRPTWTRTLAEFMCYLTE
NQKAFGYYHLSNDAKEDTTWYDFAKEILKDKAVEVVPVDSSAFPAKAKRP
LNSTMNLDKAKATGFVIPTWQEALKAFYQQGLKK
>M5005_Spy1718 sic1.01, streptococcal inhibitor of complement
MNIRNKIENSKTLLFTSLVAVALLGATQPVSAETYTSRNFDWSGDDWSGD
DWPEDDWSGDGLSKYDRSGVGLSQYGWSKYGWSSDKEEWPEDWPEDDWSS
DKKDETEDKTRPPYGEALGTGYEKRDDWGGPGTVATDPYTPPYGGALGTG
YEKRDDWGGPGTVATDPYTPPYGGALGTGYEKRDDWRGPGHIPKPENEQS
PNPSHIPEPPQIEWPQWNGFDGFDGLSSGPSDWGQSEDTPRFPSEPRVTE
KPQHTPQKNPQESDFDRGFSAGLKAKNSGRGIDFEGFQYGGWSDEYKKGY
MQAFGTPYTPSAT