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# Streptococcus pyogenes phage 6180.4

>M28_Spy1770 transcriptional regulator, MarR family
MRFGQLKSSIGLVSQKVLTAQLRAMEADGLVHREVYAEVPPRVEYSLTET
GLSLAPVIEAMSDWGQTYQEKHADLFEEG
>M28_Spy1567 transcriptional regulator
MSAKKTFFASNLKYLRLKKNMEQLELANLLGRKSSSSISEWEKGKYTPKS
GLLSDIAAIFDVSLTALMEEDLTLESKGVSYQLPQRELAMISEQLSENNY
TKWVDFAQILLEQQAKEDRELDNH
>M28_Spy1253 phage protein
MVILPDYQGVGLGTRFLKSVAEIYSCQGFDFRIVTSAKNLINALNRNTNW
KLKSYDKGNTPTGNSSIKQLAKTTRKNVKIASFLFIRKN
>M28_Spy1330 transcriptional regulator, Cro/CI family
MSIDFFQKNIILKGTTMLPEKLKTLRTEAGLTQKELAKIIQTSQQNIAYW
EKGSRNPKHKSIEKLANVFNVSTDYLLGNTDLKNPNDLDIEKVKESLKKS
LGYNGTSDIPEDELESMAQAFIEHFKNQ
>M28_Spy1863 phage protein
MENRLQKIRKEQTNLNQKDFFDQVVNKKLNLDISFRTYQNWENPKNTIKP
DKAQILADYFGVWLPYLLGNSNIRTEEQANFLAEMNKRINSEGDSFSFDM
TATESDEHDLLYNYRQLETPYKNQVRKFTRDMWELQKESKNFSPKSP
>M28_Spy1792 phage transcriptional regulator, Cro/CI family
MTQITLKAARINAGYTLKQVAGAVGKNPQTISKYEKDSSDISLGLLQKLS
SLYGVTIDNLFLGKKVRK
>M28_Spy0886 phage transcriptional repressor
MFSGHQLKTARLSKGITQSELGRLLHVNKMTISNWEKGKNIPNEKHLNAL
LHLFNVTSDYFDPNYRLLTPYNQLTISNKEKVIGYSERLLNHQIDKKSKD
LIDKPSQLYAYRVYESLSAGTGYSYFGDGNFDVVFYDEQLEYDFASWVFG
DSMEPTYLNGEVVLIKQNSFDYDGAIYAVEWDGQTYIKKVFREDEGLRLV
SLNKKYSDKFAPYSEEPRIIGKIIANFRPLEI
>M28_Spy1735 transcriptional regulator, DeoR family
MMNRLERIIQLVSQKKKIDVNSLSEQLEVSKVTIRKDLDKLESKGLLRRE
HGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCAL
LAEVLCQTKRNIKIITNSCFIANYIRQYSSCQIILLGGYYQPNSEVTVGP
LLKEMISLFHVNRVFVGTDGFNKDLGFMGKDMMRSEGVRYMADAAEEVVI
LTDSSKFSKTSLVHQLSLADVNRVITDQALDKQTQELLSSGGLVLDFVS
>M28_Spy1484 transcriptional regulator, MarR family
MLGGVYLEYDKINQYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
GKYDQVTPSDIARELMVTLGTVTTSLNKLEAKGYIARTRSRSDRRVVYLS
LTKRGRLLDRLHAKFHKNMVGHVIADMSDEEMQALVRGLGNLHQFLEDLV
>M28_Spy0840 phosphinothricin N-acetyltransferase
MLRPLSKTDCPMLQEINAKALGYLVSLDLLERQYERLIEDCHHYFLAYAD
KDTNQLLGYVHAERYETLYASDGLNLLGLAVLPAYQRRGIGSALLRALES
QARQEGIAFIRLNSASHRKEAHAFYRNLDYADDKTQLRFIKNLQGDDNDF
>M28_Spy1212 acetyltransferase
MTDKFDANDETRTVYAVVYDNDQPVSTGQFLAETKIEARLTRIVTLADYC
GCGYGAKVTEALETYTRREGFYQLTIHSELTAQTFYENLGYQSYGPKCLE
DGEYCQSLAKTILKWEKNMDIAMLIAIVGGLLGCYLYLTKNN
>M28_Spy0439 transcriptional regulator
MRFSYNKLWKLLIDKGWTKTKLRQEAGISSSTIAKLGKGENITTDILLEI
CIALDCKIEDIVEIVDNNI
>M28_Spy0298 hypothetical cytosolic protein
MTYLSQIEALLFVAGEEGLSLRHLASMLSLTPTALQQQLEKLSQKYEKDQ
HSSLCLIETANTYRLVTKEGFAELLRAYAKTPMNQSLSRASLEVLSIVAY
KQPITRIEIDDIRGVNSSGALSKLLAFDLIREAGKKDVVGRPHLYATTDY
FLDYMGINHLDELIEVSAVEPADEEIALFRTQD
>M28_Spy1091 transcriptional regulator, LytR family
MTKYPMGGLSHHEELRYFYLLRNLSYLSENEKKEFAFLKSKLEIGRAYAP
SKQHYRKSKRQEPYFEDDYYNDYSPNDLLEDDDVNHDSSFVPYGLPIYPK
EDRYLNKKTKLTARRPIDTPQPIDEDDAFLTESVARCALPRSQKRKHKKK
GCMKWFFNILGLLLMTVLMGLGLMFAKGVFDISTNKANYKPAVSQAFDGQ
ETQDGTNILVLGSDQRVTQGSTDARTDTIMVVNVGNHAKKIKMVSFMRDT
LINIPGYSYNDNSYDLKLNSAFNLGEQEDHHGAEYVRRALKHNFDIDIKY
YVMVDFETFAEAIDTLFPNGVKIDAKFATVGGVAVDSVEVPDDLRMKNGV
VPNQTIEVGEQRMDGRTLLNYARFRKDDEGDFGRTVRQQQVMSAVMSQIK
DPTKLFTGSAAIGKIYALTSTNVSFPFVVKNGVSVLGSGKNGVEHVTIPE
NGDWVDEYDMYGGQALYIDFDKYQKTLAKLGLR
>M28_Spy0464 stress-responsive transcriptional regulator PspC
METKFYKQRKNRLVAGVIAGLADKYGWDLALARVLAALLIYGTGFGVLLY
ILLAIFLPYKEDLLEERYGRGPRRRKDADVLNEEEDGWFW
>M28_Spy1569 transcriptional regulator, MerR family
MEMSQFYSTGELANLAGVSIRTVQYYDQRGILIPTALTEGGRRLYTDSDL
EQLRMICFLRDLGFSIEQIRKVLAEENAAQVLELLLVDHIATAKEDLAAK
EQQVDIAVKILDRLRKQDPQSLDFLMDISLSMKNQKAWKKRFITLIVCLT
VETLLFVGGAYFLQLTVWKYLLIPVFLLVLLGTLYWYYQNICYLCPSCHQ
TFEAKWTEFALAGHTPRTRKLTCSHCHQKSYCLELAKEDTVSRG
>M28_Spy1746 transcriptional regulator, MutR family
MMNHFGEIFKTFRESKGLRLKDVAKAGISTSQLSRFEKGETDLTISTFML
ILDESNMSIDEFMYAVHDFHRDDLNELLSKSEGFRNNSR
>M28_Spy0461 transcription accessory protein
MENNNNHNIAEALSVSLHQIEQVLALTAQGNTIPFIARYRKEVTGNLDEV
VIKSIIDMDKSLTTLNERKATILAKIEEQGKLTDQLRTSIEATEKLADLE
ELYLPYKEKRRTKATIAREAGLFPLARLILQNAQNLETAAEPFVTEGFAS
PQEALAGAVDILVEAMSEDAKLRSWTYNEIWQYSRLVSTLKDEQLDEKKV
FQIYYDFSDQVSNMQGYRTLALNRGEKLGILKVSFEHNLEKMQRFFSVRF
KETNPYIEEVINQTIKKKIVPAMERRVRSELSDAAEDGAIHLFSENLRHL
LLVSPLKGKMVLGFDPAFRTGAKLAIVDQTGKLLTTQVIYPVAPASQTKI
QAAKETLTQLIETYQIDIIAIGNGTASRESEAFVADVLKDFPNTSYVIVN
ESGASVYSASELARHEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIG
VGQYQHDVSQKKLSENLGFVVDTVVNQVGVNVNTASPSLLAHVSGLNKTI
SENIVKYREENGALTSRADIKKVPRLGAKAFEQAAGFLRIPGAKNILDNT
GVHPESYPAVKELFKVLGIQDLDDAAKATLAAVQVPQMAETLAIGQETLK
DIIADLLKPGRDLRDDFEAPILRQDILDLKDLEIGQKLEGTVRNVVDFGA
FVDIGVHEDGLIHISEMSKTFVNHPSQVVSVGDLVTVWVSKIDLDRHKVN
LSLLPPRDTH
>M28_Spy1589 transcriptional regulator, MerR family
MKEKELRRSMAVFPIGTVMTLTDLSARQIRYYEDQGLIKPERTQGNRRMF
SLNDMDRLLEIKDFLSEGLNIAAIKREYVERQGKLMQKQKALTDADVRRI
LHDEMLTQSGFSTPSQHIGNFRI
>M28_Spy0901 SIR2 family protein
MSNWTTYPQKNLTQAEQLAQLIKEADALVVGIGAGMSAADGFTYIGPRFE
TAFPDFIAKYQFLDMLQASLFDFEDWQEYWAFQSRFVALNYLDQPVGQSY
LDLKEILETKDYHIITTNADNAFWVAGYDPHNIFHIQGEYGLWQCSQHCH
QQTYKDDTVIRQMIAEQKNMKVPGQLIPHCPECEAPFEINKRNEEKGMVE
DADFHAQKARYEAFLSEHKEGKVLYLEIGVGHTTPQFIKHPFWKRVSENP
NALFVTLNHKHYRIPLSIRRQSLELTEHIAQLISATKTIYQKS
>M28_Spy1839 transcriptional regulator, TetR family
MVNRKENTKQAILKAMVMLLKTESFDDITTVKLSKRAGISRSSFYTHYKD
KYEMIDYYQQTFFHKLEYIFEKKYQNKEQAFLEVFEFLQREQLLSSLLSA
NGTKEIQAFIINKVRLLITTDLQDKFSTEELSQTEKEYQSIYLAHAFFGV
CQSWIAKGKKESPQEMTQFVLKMLTST
>M28_Spy1281 phage protein
MPDNAIAIEKIKKYLLDNNLKQVDLAVTYGKEPQDVANILAGRKKDPASN
RFVLKVISDLKIR
>M28_Spy0896 transcriptional regulator, GntR family
MTTKYQTIISNIEQDIQKQRLKKGDKLPSIRVLSKVYHCSKDTVQRALLE
LKYRHLIYAVPKSGYYVLGNVSMPDNVLNLSLEDYNNMAYEDFRLCLNEA
LSAKDKYLFHYYHKTEGLEELREALLLYLAENSVYSNKDQLLITSGTQQA
LYILSQMPFPNAGKTILLEKPTYHRMEAIVAQLGLPYQTISRHFNGLDLE
LLESLFQTGDIKFFYTISRFSHPLGLSYNTKEKEAIVRLAQRYQVYILED
DYLGDFVKLKEPPIHYYDTHHRIIYLKSFSMSVFPALRIGALVLPSGLKP
YFLTQKSLIDLDTNLLMQKALALYLENGMFQKNLRFIKRYLKQRERQLAL
FLKQNCPDIHYQLTPTHLVIDYTTSDSYRNFTLDKSDRIIITGKKRYLSI
AINQQIQSKLNSLIKNTCGKSN
>M28_Spy0283 acetyltransferase GNAT family
MLIRQVQGSDLEVIATIESDNFSPQEATTRAVLEERIRLIPDTFLVALID
QEIVGYIEGPVVTTPILEDSLFHGVTKNPKTGGYIAITSLSIAKHFQQQG
VGTALLAALKDLVVAQQRTGLILTCHDYLISYYEMNGFINQGISESQHGG
TLWYQMIWKL
>M28_Spy1828 hypothetical protein
MIIGGLYMKFFEENYSQEIPTRIKNLRKKHNITQSELGNAGQVSQVESGK
RPITSSMLVYLNALTASSYTYIVFGELDEFIENLFHYFFSSILYRDLEAV
DENLYSFMSDDLISIQSSCLSIAKTFANFNIQRKRFMISTETEMDTFHKK
DDIDVWVGGKSYNPARSFRNNPINELTVIDFEEMADILLLMLRDNLIRSF
EINVCNTLFELDKNGEPTTFNLDKIDSIINKWWSENVSTEIIPNLIKKLR
ENPLFNIGFMVNDILERMYKEDIPKSYLTSVPLVISKKARSTLSIKSNGS
QKIDKSKFAQILSL
>M28_Spy1464 acetyltransferase
MIQQSLVIEEGVPQDAKAVLSLVAAAAKETDFITGVETILEATPHELSDF
LSRSQTSFIDFCLLARLDEKVVGLLNLSGEVLSQGQVEADVFMLVAKTYR
GYGIGQLLLEIALDWAEENPYIESLKLDVQVRNTKAIYLYKKYGFRIESM
RKNDIKSKNGDDLDVYHMRKSVSQ
>M28_Spy1435 transcriptional regulator, TetR family
MMTDKALSKRSLQNLTQFNKETRRIARESMEIALLNLLETKPLGDITISE
LVTKAGVSRNAFYRNYTSKEAIIEQLLVGVIRRIFRGLKQFDIKTQAYQA
WLYLFTEAKKEAQLLKMIFKHHLHHLLTRLVTKRLKAYQKLKDKKQSHYK
RLFWSNAIVSVLTNWISDDMIVPAEEMAAMGLPLLT
>M28_Spy0034 transcriptional regulator
MLEHFGGKVKVLRLEKRISREDLCGDESELSVRQLARIELGQSIPSLSKV
IFIAKALNVSVGYLTDGADLELPKRYKELKYLILRTPTYMDDGKLQVREE
QFDEIFEDYYDKLPEEEKIIIDCLQATLDTLLSENTNFGIDLLQEYFNQI
KTKVRFRQNDLILLELYLAYLDIEGMDGQYSDKIFYDSLLDNLSEQFEQF
ELDELFIVNKIIIDISSLSLKNNRLDNLEKAIEMSQKIMAKIQDWNRMPI
LKLIEWKYFLIKQKDIIKAEQSFMKACLFAQMTADQYLENKLIQEWEKDV
KSY
>M28_Spy1085 transcriptional regulator, MarR family
MNKSIGKLITYLSRCIQQELKNVVVPFDISVGEEPYYMALTKQDGLTQDE
LTKLVKVDKAATTRMVKSLEQKGYITRETDPKDKRNKKIYLTERGRLKYE
PLSRALKEFNQKLTSEWTDEQYKIVYQSLEMLQKKFEIDNK
>M28_Spy0940 transcriptional regulator, TetR family
MTKRHTETKAYVKTALTTLLTEQSFETLTVSDLTKKAGINRGTFYLHYTD
KFDMMNHFKNDTLDDLYRLLNQAEIYTDTRQVLNQTLSYLIEHREFITAL
ATISYLKFPQLIKDFCYQFLTTITGFQDIVTNQYHIPYPYALEVYLASIE
SIISYWIANGYQETTEEVADIILKAVTLDN
>M28_Spy1203 ribose operon repressor
MRLKNPHKLILQGGKAMVTIKQVAEEAGVSRSTVSRYISQKGYVSDDARH
KIKAAIAKLHYTPNVLAQSLKTKKNQLVGLLLPDISNPFFPRLARGAEEY
LKEKGYRVMLGNISDSEALEEEYVHVLLQSNAAGIITTHDFTKRYPTLAI
PVVVVDCVDQETQYGVFSDNRAGGLLAAQTVWQAGAKEVLLIRGPLDNAE
NINERFEASFSYLQKQDVTMYVCDSQNFDFESIQLEASYNLKCYPTIDSI
IAPSDIHAIAYIHELHSQGKKIPQDVQIIGYDDILMSQFIYPSLSTIHQS
SYLMGRYAAELVYTIASQLTVKANRIKLPVHYVERETIRKR
>M28_Spy1255 ParB-like protein
MGFVDKKLSEITPYKNNPRNNDEAVGPVAESIKEFGFKVPIVVDKNGEII
NGHTRYKAAQKLGLETVPVIVADDLSEEQIKAFRLADNKVGEIAVWDLDL
LNEELNDILDLDMSAFGFELEIDDENQENLDADFEEIEDDSVLIVEAESE
EELEKLYDEFVERGFKCRVSIL
>M28_Spy1454 hypothetical cytosolic protein
MMSKVKKIPLRKSLVSGEIIAKRDLLRIVKTKDGQVFIDPTGKQNGRGAY
IKLDNQEALMAKKKQVFNRSFSMDIPESFYDDLIAYVDHKIKRRELGLD
>M28_Spy1734 sorbitol operon regulator
MKEERRRLLAKVAYLHYVQGKSQTLISKEMNIYRTTVCRMLAKAKEEGIV
RIEIADYDADLFALEEYVRKQYGLEKLDLVPNQVEDTPMDTLTNVAKTAA
EVFRHVVKDGDKIGLSWGATLSCLMDELNPKAMKDVFIYPLAGGPSHINA
KYHVNTLVYRLARIFHGNSAFMNAMVIQEDKHLAKGILQSKYFNDILTSW
DQLDLALVGIGGEPNSLEQSQWRDLLTSSDHDQLKYEKAVGEVCCRFFDQ
AGQPVYTGLQDRTIGISLEQLRRVPKTMAVATGKHKAKAILAALKAGFIN
YLVTDKETMLAVLALDEDIDLNNVLL
>M28_Spy1125 transcriptional regulator, Cro/CI family
MKEMAMEVILKNRLKELRARDGINQTEMAKLAGVSRQTISLIERNEYTPS
VIIAMKIAKVFQEPVEEVFRLVEVEE
>M28_Spy0213 transcriptional regulator, RpiR family
MPKNHRLITKIEASLEHMTSLEKGIAHFFITTDLTPQELTASEIVKRLHI
SQAALTRFAKKCGFTGYRAFAFDYLHSLQESQETFQSIHLELTKRVLMDY
DALINKTYELVNEEKLLNLAKLIDASERVYFFGKGSSGLVAREMKLRFMR
LGLICDAYSDTDGFTWANSLVNENCLVFGFSLSGKTNSVITALHQASQRG
AKTVLLTTDNQTEFDDSLDIIPVSSTHQLHYGNRVSPQFPLLIMMDIIYA
YVLAIDKPHKEKIFKNTIIDKENNGL
>M28_Spy1282 phage transcriptional regulator, Cro/CI family
MTMFEVYSRIEALAKKRGVSLQKVATDIGLSENYIYNLKSKKTANTDPIE
KIANYFNVSTDYLLGRTDNPKMAQDGHTSVAIDLKKDAEETFFFDGHELN
DEDIDLITSILETRIKNRK
>M28_Spy1812 phage protein
MSKKNAIRKLKEFHRWQRIANSLDLTYTELYQFDIEYHPTRRKHLEISRE
CALEELDAIRYAINQLSKVEYRQILIECYLISEEKTQQDIMEELNRSQSW
YYESKKRALLEFVEFYRDGALKNNVRL
>M28_Spy0212 N-acetylmannosamine kinase
MKHYLAIDIGGTAIKYGLISETGDLLEKEEMATEAYKGGPSILEKVKGLV
KTYQDQMDLAGVAISSAGMVNPDKGEIFYAGPQIPNYAGTQFKKEIEETF
GLPCEVENDVNCAGLAEAISGSAKDYPVALCLTIGTGIGGCLLFNSQVFH
GSSHSACEVGYLHLSDGQFQDLASTTALVQEVALAYGDDISQWDGRRIFE
QAKAGDAICIAAISKQVDYLGQGIANICYVVNPNVVVLGGGIMVQKDYLA
DKLKTALDSYLVSSLAKKTQLKFASHGNNAGILGAYYHFKQKNERSCSFI
TLEKIENNLASS
>M28_Spy0963 transcriptional regulator, GntR family
MKNGIKLDIPFFFLYHLISTNIYITQKGDHMSWKFDEKSPIYAQIAQHVM
MQIISQEIKSGDQLPTVREYAEIAGVNPNTMQRAFTELEREGMVYSQRTA
GRFVTDDQKLIARKRRELAISELESFITNMTKMGFSHTEIIPVLTSFLKE
DSQ
>M28_Spy0276 putative regulatory protein
MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERVEELPLL
VIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENVISRIEQEVRTTYE
NEVSSTAIGNLVMDELAELDEITYVRFASVYKSFKDVDEIEELLQQITNR
VRGKKKRLNNDETN
>M28_Spy1659 transcriptional regulator, MarR family
MTYRIKRGNQMSHLDKNTALKAMVVFRKAQRTLDAFGADIFKKADLTATQ
FSVLEVLYTKGCMRINHLIDSLLATSGNMTVVLNNMERNGWISKCKDKTD
KRAYVVTLTDKGTRLIEAVLPKHVARVEEAFAVLTEKEQLCLIELLKKFK
QL
>M28_Spy1769 trehalose operon transcriptional repressor
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLL
TKAGLILKKQGRGTQVIKHHQIMFPISELTSYQELVSYSNLDSKTNVIAI
DKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIM
TREIAEHSIYQYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVV
SVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRPK
>M28_Spy1831 transcriptional regulator
MMLSKSLQVPLEQLIAEDIPKMTLIIKDEEIKQCDRNTHIMLFGTLLIAI
SIYPIMSWLGWWGYGPVAILWLIIMRIALRIERFKKTYDVQTYR
>M28_Spy1352 glucokinase
MRHDRLFYYNKGEHLMSLLCIDIGGTSLKFALCHNGQLSQQSSFPTPSSL
EKFYQLLDQEVARYSAYHFSGIAISSPGAINKEKGVIEGASAIPYIHHFK
IQEALEERLHYPISIENDANCAALAEATLGAGKGASSLAMLVLGTGVGGS
LVIDGKIYHGAHLFGGEFGFMIMNDRYQTFSQLGTVVNMAKRYSAIVNNG
KDYTGKAVLALAEQGDHLALKERQVFLQSLAIGIFNIQHAFDPQLILIGG
GVSQADFLLSAIEAELDKLYQAVEISDLRPQLAICHFKNEANLLGAAIDF
YQEHKEA
>M28_Spy1420 trans-acting positive regulator
MIWLIIFMKLVSNYLKRGSAMKIEDLMDKERKAQYRLLVTLYHAKETLRL
KDLMRLSNLSKVTLLKYIDNLNHLCREQGLACQLLLEKDSLSLKENGQFH
WEDLVALLLKESVAYQILTYMYCHEHFNITNLSVELMVSEATLNRQLAHL
NQLLSEFDLALSQGRQLGSELQWRYFYLELFRHTLTRQGIDALVNQLDAS
HLATLIERLIGQSLSAEALEQLLIWLAISQARMSFQKGYNDHFLRDSDFM
TSNIFFKRLESMLLHYLRRYALEFDAFEAKSLFVFLHAYPLLPIASMKYS
LGFGGPIADHISEALWLLKKAHVIIHQTKEEIIYGLGIFFSKAYFFKGAI
LSQPTNSQYLYQLVGEDKRALLRVIINHLVLQMGQETDFSQQLSDDILAL
LVFSIERHHEPLLVGLALGQNKVEAAIAELAIRRHLGHRRDFQLMPYDHQ
KVYDCLITYQTVYLPRQDLPYYRLKQYSSPYELTALEAFLKDLFQQKNTR
EEELSLSPAAKSSFAHKTV
>M28_Spy1042 transcriptional regulator, LacI family
MMTSKITIKDIAREAGVSVATVSYVLNQRNDQKISEETRNKVLHISNLLN
YTPNQAARALVTQQSNSVVLYYKYADSILARAEQLHTISFLSRLLHEQDY
QLVCLNEDSIEKFDWADLILTLDVDNDTFYKIGKLNFKPLIAIDSFVNDP
LFFQINTDYAALKDQANQFFKDEPYTLLSLPITNRERYEHVSAFFPSLHI
VNDLRELTYFEKENLLLIDESLDQFFVNSSQKLYCPRFSPKKGQVILEAI
EWAKKRQPDKKHNLLV
>M28_Spy1843 phage protein
MNAKEQLKELKPLFALMTLFEEQRDKDIKLMNAFRNPELLNGIEKGTAKQ
LLYLAKERDKRLAMIATLQDERQIAVIKARYVDDLSWDEIPDKLGYSRNT
VFKLHREALEVLDEP
>M28_Spy1096 cytosolic protein containing multiple CBS domains
MIIIMSKHQDILDYLEKLAIGKKVSVRSISNHLKVSDGTAYRAIKEAENR
GIVETKPRSGTVRIEKKGRVRIDRLTYSEIARISDSEVLAGHAGLGHEFS
RFSIGAMTQQNIRRYLVKGGLLIVGDRETIQLLALENHNAILVTGGFPVS
KRVIEMANNQRIPVMVTHYDTFTVATMINHALSNIRIKTDLKTVEQVMIP
ITDYGYLCENSSVEEFNTLIKKTRQVRFPVLDYKRKVIGVVSMRDVVDQL
PTTKLTKVMSKNPITARPNTSLANISQKMIFEDLNMIPVTDEENNLLGMI
TRRQAMENLPNHQPNNPYTYSEQILSNLEETVDYYQVVVEPTMIDSAGNM
SNGVISEFLKEISIRALTKKHQKNIIIEQMMVYFLHAIQIEDELKIYPKI
ITENRRSSTIDIEIFVDDQVIAKAIITTKIN
>M28_Spy0635 transcriptional regulator, TetR family
MSDMTKDRQIKKTKTAIYSAFLALLQKKEYSKITVRDMITLANVGRSTFY
AHYESKEMLLKELCEELFHHLFRQKRNVTFEDYLVHILKHFEQNKDSIAT
LLLSNDPYFLLRFKNELEHDVYPNLRCKYIDKTTIPEVFLKQFVLSSFIE
TLKWWLHQRQRMSANELLKYYLELIK
>M28_Spy1329 transcriptional regulator, Cro/CI family
MIDVSKKLKQLRIDRGIAKSRLITYLSITLRTYDRYEDGSRTPDLVTLMK
LSDFYQCSLDELVKGNTNDTLVDRALIVSYRDLKDKGLNDKLAHGLVKQV
YDTYEFEKIPQISDANRIKFIYKEDLVTLLESIVSKIQEEKKCD
>M28_Spy1384 transcriptional regulator, LysR family
MIRQGESYLDIKQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEK
RENVKLFKRKRGRIIGLTYLGDNYYKDAQKVLSLYDDMFLKLHDHSKGLK
GSISIGIPPLILSVVFSEVMPKLILENPGIQFNVKEIGAYQLKNELLVGN
VDVAVLLSPTGIADNLVETYEIQRSELSVCLSPRHRLASKKVIQWEDLTD
EQLALFDPSFMVHHLVLEACERHQVRPNIILTSSSWDFMLNSTKINHNVL
TICPKPITELYQFKDIKCILMERPISWRVVLTRLRKKSYSEIEAYIMDDL
LQSFFK
>M28_Spy1685 acetyltransferase
MIPIKALKIKVETVMKIIEYKGNYRDDLIFMVLEAKNALRRIPSINPDLL
TIETSYLEKGDCFWLAVNEESRVIGSIAYSSIPKTNEVFLHRLFIKPSLK
HQGIGSQLLTFAEDYLRKIGKSHVRIHLGQPKEQWFESYRFYPKHGYQFY
DDTHLIKKLI
>M28_Spy1846 phage protein
MIFIEHGLTPKQEKFMVAMVTSKTITEAAERAGITRGTAHRYLKDITFKK
ACRRYRSELMQQTTSLLQSASIEAVEVLRNIMLDDSISPYARQQSAQTIL
STAYKAHELDDIVEMVEELEARFEDEQ
>M28_Spy0860 transcriptional regulator, LysR family
MSQGKIDIGLLSFLSIQKDITIELLQTSTKGYKVSIVLLKQHPLAQHPQL
KLKDLKGYKIASLNDHYMLGEMLPRKCRALGYEPDIVFKHNDWEVLIHSL
HDLNTLTILPSDFESLNQVDNLVWIPLQDKNNFYPIGIAYRDDASFSPVI
EEFLSLLKTN
>M28_Spy1861 phage protein
MNRQVSIFEEVNDQGGAFQVVTTMTFHDRLLDIYGNIQEPLFRARDVAEM
IDHSKTRNGYYDVQSMLRKVDDDEKVKGVPLEGATKNFRSGQKVWFLTEH
GLYEVLMRSSKPKAKEFRKAVKNILKEIRLNGYYMQGELVQNSQPTPDID
DLSYIKQKLTDLQDVDSLQDLRWKMAKLYHVIETLDEY
>M28_Spy1791 phage transcriptional repressor
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKG
RSLPTAGNVQKLADFFGVLKSDIDPRFDSNNIETNSNIIPSTLQKVTSTL
SQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYL
NDVQVETIELPVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDI
GVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSDFRIIGEVIGS
FTSKS
>M28_Spy0428 transcriptional regulator
MLGKWENMKSKLGATLRKVRKGKQISLCFVADEHLSKSQISRFERGESEI
SCIRLINILDKLHITLDEFLILHDEDYTNSETFANLVQYIRKQYSSQNIN
NIACLLSDTSDYTLNSFEKTMVKSILHTMDSSIIPSDDELLQLTDYLFKV
EKWGYYEILLLGNCVRTINYNSYFLLTKEMLNNYIYSSRNKTNKRIVTQL
AINCFILSINKEEFSNCSYLIDEIKSLLDNELNFYEQTVFLYATGYFEFK
RQLETGVEKMKQAIQVLDILNEDKLKLHYADHFDKLVNKD
>M28_Spy1835 transcriptional regulator, PadR family
MYFPVSATLIEFLILAIVEKNDSYGYDISQTIKLVANIKESTLYPILKKL
EKAGFLTTYSQEHQGRKRKYYAVTSSGRAQLIFLKKEWQSYKFALDGIIE
GSLRHDKD
>M28_Spy1636 transcriptional regulator, Cro/CI family
MKNLKLKAARAGKDLSQQALADLVGVSRQTIAAVEKGDYNPTINLCIAIC
RVLDKTLDDLFWEVDDSH
>M28_Spy1381 DNA-directed RNA polymerase omega chain
MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGATPTQEFKSVKSTLQA
LEEIESGNVVIHPDPSAKREAVRAKIEAERLAKEEEERKIKEQIAKEKEE
EGEKI
>M28_Spy1021 phage protein
MLCLGGIMWGKIEALLIEKKMTKYELSQKAGLNQNCLIDLKKGRKKSLKF
DDVVKIADVLGVSLDEFR
>M28_Spy1014 phage DNA/RNA helicase
MMIVSPPGSGKSVVISDIAKSATQKNGHVLFLVHRKELIDQITNSFKFHG
IDMNKVDLMTVGKAKNRLDKLTKPTLIITDEGHHGKASTYQIIYEYFSDV
PRIGFTATPWRLSGDGFTDTYDVMVLGKTVEWLINNNKLAPYDYYSVLSI
DTAKLKVQNGDYSNKSIDESFGKKIFGDVVQEYIKKANGQKAILYAHSVE
ASQAFAKEFQSMGINAIHADAKTPKAKRDKIMKDFRDGKIQVICNVDLIS
EGFDVPDCTVTILCRPTKSLVLFLQQSMRSMRYQPNKKAIILDHVGNWNI
HGLPDTPHHWENYFRGGWKKKSNKTNTVHAKECSVCSALWPLSQQLCELC
NHDFGLKEKQEKERIEAELELIKRERFRIKQLANKKFGKDLKTNWEIAQA
RVKDAGKGKPLYKLIYFYLKTDWVETNVNELAEVTGKSEKEIYSAYNWLK
KKLRG
>M28_Spy1356 transcriptional regulator, GntR family
MTKLLYKKIYHFIKEQIASGRLQIGDRLPTEKELSEQFSVSRITSKRALV
ELEQEGLITRSRGKGSFVAEKQVTSPEANKDLLLILPFTSDYELGDYAKG
IMTSIAETGYRLMVQLASTVRLDTLSDYAGIIYYPEDVNHSIDFLFYCDH
HHIPLVLLDKSLDLFQFPSVVADNKGGACQLTQHLIEQGCDQISFVATGS
FGEVSSVRDRYLGYLAAMAESSLKSHYFPKTETETTDAYLDRLVKTLSET
TATKRGLVVENDWLAIQLIQKITQVGLYIPDQVAIVGFDNSQASRLLSPK
LSTAAQDFYQMGQEAAKVLLQIIHEPDQAVVSCQLPVQVFIRESSH
>M28_Spy0189 transcriptional regulator, MarR family
MSQVIGDLRELIHQIEQISDEIAKKYDVEHLAGPQGYVLVFLAKHQNQEI
FVKDIEKQLRISKSVASHLVKRMVKNGFINVMPSQVDKRYKQVVLAQVGR
DKLPLLRECRKDIEHYFLKEITKEELLTAKKVIEQLKQNMLTYKGDNDA
>M28_Spy1545 transcriptional regulator
MIFMEIGQQIIRYRKQQALSQEKLAEKVYVSRQSISNWENDKTYPDIHSL
LLLSQIFQVSLDQLIKGDIEKMKYTITQVDKKNFKRDTKVMVTLMILLMI
SSYPLSLFLRVARTWHFCFIIDNYYDLC
>M28_Spy1018 phage protein
MKTKIEIMRDFFKENPESTQRQASEKLGFTENTVKQYIWRDAKRGYCIKD
EEGRVTYLNIEDELSLINEWKSEIRRELIEQLLSANRHETSSEQIRMNAK
TINQILGEI
>M28_Spy0153 transcription antiterminator, BglG family
MMILDKKSYDLLSYLLKLETPETVMAISHALNQSRRKVYYQLDKINKALP
KGVDQIISYPRLGILLTADQKAACRLLLEEVTDYNYVMKSDERRRLSSIY
IAVSTERVTIDKLMQINDVSRNTILNDLTELREELEDKQYKIQLHATKAR
GYYFGCHPMALIQYLYKLLVDVYQGGNTSFIDIFNRKLSEIQGLSVYFSK
DILTYFHEYLFLSQASLGKTINTQDSQFMLQILPFMLLSYRNMRLDSETK
SALKQEFHLIWKRKEYHIAQDLARELYHNFKLHLDDIEVSMVAMLMLSFR
KDQDHHVESQDYDDMRATISHFIDQLESRYQLHFTHKQDLLKQLTTHCKA
LVYRKAYGIFLVNPLTDHIKEKYEELFAMTQSCATILEQDWTISLTDDDI
AYLTIHLGGELRHNNTEQEKTKLVIVSDDGIGIQKLLFKQCQRYLANGQI
EAVFTTEQYQSVYDLLAVDMIVATTDTLKTKIPMLIVNPILSDDDIIKLI
RFSKQGRLSEHSRFSTELTKAIEAVVKDESDRYALVSKIEKLIHRELL
>M28_Spy0116 transcriptional regulator, LysR family
MNISSLAYFIEIVNCDFNLTKAAQKSHISQPALSSYIKTIEKEEGVVLFQ
RQKGRLVGLTSVGERFFENAKVVIASHEQLMADLRSESKKYKGEISIGIP
QLISGIVFSELIPKLIEENPEAKFHIVETGAYELQKKLFLKEVDFAILLT
PTTLDATIADIDILLRDQLCLYMSHKTFQETFDSNPNISIKALHRQNLVT
FDKTFMINHQLTTLFEEANSLPVVKCYSASWDFLLNCTRYSSYLTILPRP
ITHFAHMDGLVEVQLTEHPKWEVVLASLKHNKTSHLKHYIKHTILDYFMN
QRF
>M28_Spy1793 phage transcriptional repressor
MTVGDKIKTIRLNLGETMEEFGKRFGTSKGTVNNWEKGRNLPNRNSLLRI
AQLANQTVSDFLAITD
>M28_Spy1030 phage transcriptional repressor
MNILGNSIKEIRKSKKMTQKELAKLTGFKQNTISNHENGNRQLDEVDIRK
YAKALKIEPQQLFDYSSSPTNPQVELIPSTLQKINSTSSQLEHSRQIIVL
DTAETLLEQQKEIKNNEDTIAELFSYNYYDHAASAGTGQYLNDVQVEKIE
LPVDYDADFVIPVYGDSMEPKYHSGDYVFVKLSVELTDGDIGVFEYYGDA
YIKQLLINAEGAFLHSLNQCGDYPDIPIDRDSDFRIIGEVMGSYRER
>M28_Spy1319 transcriptional regulator, Cro/CI family
MEKLGDRLRKQRQLNKLTQQELADRIGINRGAYSNWENGKREPSFQN
>M28_Spy0522 transcriptional regulator, GntR family
MNKMPKEQPLYLQIVDDLEVKIKKSMTENDKLLSERELSDLYGVSRITIR
LALKELELRDLIYKKQGKGTYVSGIKEPVTDLSSTYSFTEQMKKVGKTPK
TEILSFEQYQVTPYLSGLLEFDLDTEVFELERLRIADDMPLMFERSYIPA
QPFQGLSIADLKRKALYDIFAKDYQETIRLAEEEFYASIALDYEADLLGI
KKGDPVLHIIRKTYNDKNILIEFTFSIARADQFRYRVQHHPNG
>M28_Spy0660 two-component response regulator
MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNAYDIMIL
DIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLT
KPFSLKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLA
SKEGKLMAFLMLNQGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKL
LAIQANVIIAGDKDTSYCLLEK
>M28_Spy0788 phage associated transcriptional regulator
MYPRIRNLREDNDFTQKFVANLLSFSHANYAKIERGEVALMADVLVQFSK
LYNVSIDYLLGQTDYPYRFHNK
>M28_Spy0889 transcriptional regulator, GntR family
MNNRLEECGMLPAYIKIHDAIKKDIDLGIWPIGSRLPSERHLAEHFTVSR
MTLRQAITLLVEEGILERRIGSGTYVASHRVQEKMRGTTSFTEIIRSQGR
QPSSKLLSYQKQLASDTEVKELNLDKTDLVIRMERIRYADSVPLVYEIAS
IPEKFIKTVKRADITEHFFHSLIANGYEIGKSKQTIYAKLASERVASYLE
VAKGHAILALTQVSYFTDGKPFEYVRSQYIGDRFEFYLENN
>M28_Spy0162 ParB-like nuclease
MSNFISPVYEIKSIPIEKISPNDYNPNSVAPPEMKLLYDSIKSDGYTMPI
VCYYDKEEDRYSIVDGFHRYRIMLDYSDIYERESGRLPVSVIDKSLDYRM
ASTIRHNRARGSHDVDLMSQIVKDLHECGRSDNWIAKHLGMDKDEILRLK
QITGLASLFKDHEFNQSWEPEELLNE
>M28_Spy1862 phage protein
MLITENIAVKVRKKRAVKQLGKVELSKKLGITPPTLSKIEAGNYKAPKRI
YASVMEWLAEDY
>M28_Spy1571 hypothetical cytosolic protein
MVLFLIRIFSDSDKEENMGIEKTVSELADILGVSRQAVNNRVKSLPEEDL
DKNEKGVTVVKRSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKN
TEITRLYEQLKAKDAQLASKDEQMRVKDVQIAEKDKQLDQQQQLTAKAMA
DKETLKLELEEAKAEANQARLQVEEVQAEVGPKKGFLTRLFAK
>M28_Spy1566 transcriptional regulator, Cro/CI family
MTKSTLKELRTTKKMTQQELSHLTGISVRTIARYEKDTKKLRRAKYEKLK
GIAQALAVSVDDIFLGIDSEFMN
>M28_Spy0402 exoribonuclease II
MMKERIMTYLKEHGKSNVNDLAAALEMAGAKHFPSLIKTISKMESQSLLR
FSDDGSLALRKEREKKKEPTVQGVFRANKAGFGFLHVDENEDDMFIGRND
VGYAIDGDTVEVVVKKPADRLKGTAAEAKVVAIVDRSLKTAVGTFILDDD
KPKYAGYIRSKNQKIQQKIYIKKEPVVLKGTEIIKVDIDKYPTRGHDYFV
ASVRDIVGHQGDVGIDVLEVLESMDIVSEFPAEVLAEANAISEAPTAKDL
IGRVDLRQETTITIDGADAKDLDDAIHIKLLDNGNYELGVHIADVSYYVT
EGSALDKEAIARGTSVYVTDRVVPMLPERLSNGICSLNPNVDRLTQSALM
EINSQGHVVNYQICQSVIKTTYRMTYSTVNDMIAGDEEALQEFASIADDV
TLMVALHRILEAMRSKRGALNFDTQEAKVIVNDKGMPVDVVLRQRGIAER
MIESFMLAANECVAEHFAKAKLPFIYRIHEEPKAEKLQQFIDYASTFGIH
IQGTANKISQEALQAFMAKVEGQPGAEVLNMMLLRSMQQARYSEHNHGHY
GLAAEYYTHFTSPIRRYPDLLVHRMVREYSQPSQEKRDHFTQIIPELATS
SSQLERRAIDAERVVEAMKKAEYMAEYVGEEFDGIVASVVKFGFFVELPN
TIEGLVHITSLPEYYHFNERTLSLQGEKSGKVFKVGQPIRVKLVKADKET
GDIDFEYLPSDFDVVEKIKMSDKASRRDRRKSSKSSKGTKKKEPKEVAKA
KTKGKTKKGSKKPFYKEQAKKKSRKRS
>M28_Spy1406 ATP-dependent RNA helicase
MSFKDYHFKQYVQQALEEIGFVNPTEVQKRLIPIVNSGRDLVGESKTGSG
KTHTFLLPIFEKLDEAKAEVQVVITAPSRELATQIFDACKQIAKHFQEEI
RLANYVGGTDKLRQIEKLKGSQPHIVIGTPGRIYDLVKSGDLAIHKATTF
VVDEADMTMDMGFLDTVDKIAASLPKSVQILVFSATIPQKLQPFLKKYLT
NPVIEQIKTKTVIADTIDNWLVSTKGRDKNGQLLEILKTMQPYMAMLFVN
TKERADDLHAFLTANGLKVAKIHGGIPPRERKRIMNQVKKLDFEYIVATD
LAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTGRNGMAGTAITLYQPSD
DSDIKELEKMGIAFTPKVLKNGEFQDTYDRDRRQNREKAYQKLDTEMIGL
VKKKKKKVKPGYKKKIQWAVDEKRRKERRAENRAKGRAERNAKKQHF
>M28_Spy0616 transcriptional regulator, LysR family
MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSIKDLEAELGFQIFNR
TTSGTVLTSQGLVFYEKALEVVKSFDSFEKTFSQADLDQNEFSIASQHYD
FLPPLITAFSQQYDGHRVFRIFESTTIQILDEVAQGNSEIGIIYLNVDNQ
KGLFQRMDKLGLEYVSLIPFTTHIYLSKTHPLANREALYLSDIQGLPAVR
FTQERDEYLYYSENFVDTSECPRIYNVSDRATLNGILERTNAFATGSGFL
DHRSVNGIKVIPLADHIDNQMIYVKRKDKNLSVAGATFVTILKDYFDKRR
KALT
>M28_Spy0426 acpA, ribonuclease III
MKQLEELLSTSFDIQFNDLTLLETAFTHTSYANEHRLLNVSHNERLEFLG
DAVLQLIISEYLFAKYPKKTEGDMSKLRSMIVREESLAGFSRFCSFDAYI
KLGKGEEKSGGRRRDTILGDLFEAFLGALLLDKGIDAVRRFLKQVMIPQV
EKGNFERVRDYKTCLQEFLQTKGDVAIDYQVISEKGPAHAKQFEVSIVVN
GAVLSKGLGKSKKLAEQDAAKNALAQLSEV
>M28_Spy0075 adcR, transcriptional regulator, MarR family
MGTLEKKLDNLVNTILLKAENQHELLFGACQSDVKLTNTQEHILMLLSQQ
RLTNTDLAKALNISQAAVTKAIKSLVKQDMLAGTKDTVDARVTYFELTEL
AKPIASEHTHHHDETLNVYNRLLQKFSAKELEIVDKFVTVFAEELEG
>M28_Spy1215 ahrC.2, arginine repressor
MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSRDMKELN
LVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLP
GLAQSFGSILDAMQIPEIVATICGDDTCLIVCEDNEQAKACYETLSHYTP
PFFFSNK
>M28_Spy1168 argR1, arginine repressor
MLPRHIRSLRNMKKSERLELIKKMVLTHPIETQHDLLRLLAEHGLELTQA
TISRDMNEIGIVKIPSGSGRYIYGLSQDSGKKIVQGPRSIKSTILAVSDK
TKGLEQHLYLKVVPGNSKLIKRYLLADFSKAIFSLIADDDSLLLIAKSPS
EADMIRQEILLWMQGIT
>M28_Spy1816 argR2, arginine repressor
MNKMERQQQIKRIIQAEHIGTQEDIKNHLQKEGIVVTQATLSRDLREIGL
LKLRDEQGKLYYSLSEPVATPFSPEVRFYVLKVDRAGFMLVLHTNLGEAD
VLANLIDNDAIEDILGTIAGADTLLVICRDEEIAKRFEKDLAAGL
>M28_Spy1827 cadC, cadmium efflux system accessory protein
MGCVRLGEKIMKKDSICQVGVINQQNVTTATNYLEKEKVQKSLRILSKFT
DNKQINIIFYLLAVEELCVCDIACLLNLSMASASHHLRKLANQNILDTRR
EGKIIYYFIKDEEIRDFFNQLG
>M28_Spy0412 ccpA, catabolite control protein A
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDY
RPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLA
SSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAG
TVDLDHQLPSVNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRL
AGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSGATAAYVAEDE
LAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGA
VSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK
>M28_Spy0920 ciaR, transcriptional regulatory protein
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGIYDLILL
DLMLPEKNGFQVLKELREKDIKIPVLIMTAKEGLDDKGHGFELGADDYLT
KPFYLEELKMRIQALLKRTGKFADKNISFGNLVVDLARKEVKVEGKVVEL
LGKEFDLLVYLLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKIRKK
LKGTRFVNRLQTLRSVGYILKNNE
>M28_Spy0872 citG, transcriptional regulator, GntR family
MNPIIEAVKQNLDLSRNIPLKIAFYNALKTTIILRQIPVGSRINEKEFSI
ALNISRTPIRYALGLLSEEHLVEHIPKKGIIAKGVSIKDACEIFEIRKAL
ETLATVQAMHLMTEEDFKVMHNLLEDCETFIAEDDTNRILDNFNAFNNLI
YSYSQMVRLKEIVTELQAYLVYFRKISISSVERRKRALSEHWMIYRGMKN
KDHEQITLITHEHLNSSLEFILKEMRPEQND
>M28_Spy1501 codY, transcription pleiotropic repressor
MQKRVSFVIMKAQIIQRKRKKMPNLLEKTRKITSILQRSVDSLETELPYN
TMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTY
VKAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGS
LIIWRNDNEFSDDDLILVEISSTVVGIQLLNLQTENLEDTIRKQTAVNMA
INTLSYSEMKAVAAILGELDGNEGRLTASIIADRIGITRSVIVNALRKLE
SAGIIESRSLGMKGTYLKVINEGIFAKLKEF
>M28_Spy1449 copY, copAB ATPases metal-fist type repressor
MMNQNISAAEWEVMRVVWASGDIKSSDIITILRKKYQWSDSTIKTLIGRL
VEKKALGTYRQGRAYIYQALLDETLLQKEALATVLDGICQRQHTHLLLER
LYDLPMTLEEIEAFQELLEVKKENAVLEVSCNCLPGQCHCQKKETY
>M28_Spy0274 covR, response regulator
MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALEKEFDLI
LLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYI
VKPFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGD
DEISLTKREYDLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIR
YLRGKIDIPGKESYIQTVRGMGYVIREK
>M28_Spy0681 cpsY, transcriptional regulator, LysR family
MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMGITIFNR
NPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYA
FVVNAFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYN
RDVLTKLFDDNHLTASPLFKAQPHIFVSKSNPLATKSLLNMDDLRDFPYL
SYDQGIHNSFYFSEEMMSQMPHSKSIVVSDRATLFNLMIGLDGYTVASGI
LNSNLNGDQIVAIPLDVPDEIDIVFIKHEKANLSKMGERFIEYLLEEVTF
D
>M28_Spy1581 crgR, transcriptional regulator, GntR family
MSTNDLTKKLKKLKHVQVYNTIFQLIQDGTYSPGMQLPSEPELARQLNVS
RMTLRKSLALLQEDHLIKNIRGKGNFILKTPETKYHQGFEYLQHPIYASL
SSDITKVELEYRIEVPTVAITASLKQETPVVIIVDRWYHSQNKAIAYSLS
FIPIEVISKYAINLNQEEPLLTFLEEKIYESGKASHSCNQIGYTKTGNYT
ATKYTLSENSAFILIQETLYNGKDILVSTKHYVPADLFDLKVQSQSCQSD
TH
>M28_Spy1751 csp, cold shock protein
MYMAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQTNGFKTLEEGQKVA
FDVEEGQRGPQAVNITKLA
>M28_Spy1750 ctsR, transcriptional regulator
MPTKNTSDSIEEYIKELLAKSGIAEIKRSMLADSFQVVPSQINYVIKTRF
TESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGNLMATIEDCISEQVFTD
SIQLLFDEHLLTEREGNIILAVASDDVLGTDGSTIRARMLYRLLQRIDRK
GSN
>M28_Spy1148 deaD, ATP-dependent RNA helicase
MKFTEFNLSQDIQSAVVTAGFEKASPIQEMTIPLALEGKDVIGQAQTGTG
KTAAFGLPTLNKIRTNENIIQALVIAPTRELAVQSQEELFRFGREKGVKV
RSVYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALILDHVETLILD
EADEMLNMGFLEDIEAIISRVPADRQTLLFSATMPAPIKQIGVKFMKDPE
HVQIKNKELTNVNVDQYYVRVKEQEKFDTMTRLMDVNQPELSIVFGRTKR
RVDEITRGLKLRGFRAEGIHGDLDQNKRLRVIRDFKNDQIDILVATDVAA
RGLDISGVTHVYNYDITQDPESYVHRIGRTGRAGKSGESITFVSPNEMGY
LSMIENLTKKQMKPLRPATAEEAFQAKKKVALKKIERDFADETIRSNFDK
FKGDAVQLAAEFTPEELALYILSLTVQDPDSLPEVEIAREKPLPFKYVGG
GHGNKNGKGGRGRDNRNRGDRRGGYRGDRNRDERDGDRRRQKRDKRDGHD
GSGNRDFKRKSKRNSKDFFNKEKKSSAKNTGFVIRHKGE
>M28_Spy1110 deaD2, ATP-dependent RNA helicase
MNIETIVKGRRMITKFPPQWQEKLDQVAFTHLTPIQEQAFQPIVDGKNFL
GISPTGTGKTLAYVFPSLLALTPKKSQQLLILAPNTELAGQIFEVTKDWA
QPLGLTAQLFISGTSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMS
VNTIVLDEYDELLGDSQYDFVQKISHYVPRDHQMVYMSATNKVDQTSLAP
NTFCIDLSEQTNDAIQHFYLMVDKRERTDLLRKFANIPHFRALVFFNSLS
DLGATEERLQYNGAAAVSLASDINVKFRKTILEKFKSHQLSLLLATDLVA
RGIDIDNLDYVIHFDVARDKENYTHRAGRTGRMGKSGIVITFVSHPEDLK
KLKKFAKVSEISLKNQQLHFIN
>M28_Spy0514 dinG, ATP-dependent helicase
MFCFIDIACYNRLTMTQKKLRKYAVVDLEATGAGPNASIIQVGIVIIQGN
KIIDSYETDVNPHESLDEHIVHLTGITDKQLAKAPDFGQVAHHIYQLIED
CIFVAHNVKFDANLLAEALFLEGYELTIPRVDTVELAQLFFPRFEKYNLS
HLSRQLNIDLAEAHTAIADARATAILFLRLLQKIESLPIECLESLLAYSD
SLLFETAMVIQEGLAKAKPYDPNKYIKIRQILLPKGSKALKPYQISKSFP
INMALLGLEERPKQTQFAQLIDEDYHQGVASFIEAQTGIGKTYGYLLPLL
AKEDQNQIIVSVPTKLLQDQLMAGEVAAIQEQFHIACHSLKGPANYLKLD
SFADSLDQNDQNRLVNRYKMQLLVWLLETKTGDLDEIKQKQRFAAYFEQL
KHDGDIKQSSEFYDYDFWRVSYEKAKTARLLITNHAYFLHRVQDDKDFTR
NKVLVFDEAQKLMLQLDQLSRHQLNLTVFLQTIQAKLSNPLPLLEKRLLE
SLSFELGQVSSDYYQNKEHQLAHDWSRIAGYAKELTGADYQELQAFFATS
DGDYWLSSEKQEEKRVTYLNSASKAFIHFQQLLPETVKTYFVSATLTISS
EVTLADLLGFEEYLYHVIEKDKKQDQLVLVDQEAPIVTEVSDQIYVEAIA
KRIESLKQEGYPILVLFNSKKHLLLVSDYLDQWQVPHLAQEKNGTAYNIK
KRFDQGEQTILLGLGSFWEGVDFIQADRMITLIARLPFDNPEDFFVKKMS
HYLLEKGKNPFRDYFLPMTILRLKQAIGRTMRRQDQKSVVIILDRRLLTK
SYGQVILEGLGQEFLISQQNFHDCLVETDCFLI
>M28_Spy0807 dpiA, transcriptional regulatory protein
MNVLIIEDDPMVDFIHRNYLEKLNLFDRIISSDSMKAVQSILTDYAIDLI
LLDIHITDGNGIQFLEKWRAQHIPCEVIIISAANDGNIIRDGFHLGIIDY
LIKPFTFERFQESIQQFVTHREHLANQQLEQAQIDQLKCLTSKKDTKNKQ
LLEKGLSESTFQWIIENIKAFDQPFTIQELASACHLSHVSVRKYIAYLEE
NKQLNSQQIFTKVGRPYRVYW
>M28_Spy0200 fasA, response regulator
MMNIFILEDDFIQQTRIESIVVGILKETRIPCNQLEVFSTPQKLFESIQE
RGDHQLYFLDIEIGEYTRCGLELAAAIRQKDPNAVIVFVTTHSEFAPISF
KYKVSALDFIDKAGGQKQFKEQIEECIRYTYDMMSSRESKDMFLFETPQT
RLKLPYKDILYFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCH
RSYLVNLDKVVRIDKSKQLLYFENGDSCMVSRLKMKCLFERWEALR
>M28_Spy0720 fbp, fibronectin-binding protein
MWYNEEIRIQKGETMSFDGFFLHHLTNELKENLLYGRIQKVNQPFERELV
LTIRNHRKNYKLLLSAHPVFGRVQITQADFQNPQVPNTFTMIMRKYLQGA
VIEQLEQIDNDRIIEIKVSNKNEIGDAIQATLIIEIMGKHSNIILVDRAE
NKIIESIKHVGFSQNSYRTILPGSTYIEPPKTAAVNPFTITDVPLFEILQ
TQELTVKSLQQHFQGLGRDTAKELAELLTTDKLKRFREFFARPTQANLTT
ASFAPVLFSDSHATFETLSEMLDHFYQDKAERDRINQQASDLIHRVQTEL
DKNRNKLSKQEAELLATENAELFRQKGELLTTYLSLVPNNQDSVILDNYY
TGEKIEIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTKQSITYF
ESVDYNLSQASIDDIEDIREELYQAGFLKSRQRDKRHKRKKPEQYLASDG
KTILMVGRNNLQNEELTFKMAKKGELWFHAKDIPGSHVIIKDNLDPSDEV
KTDAAELAAYYSKARLSNLVQVDMIEAKKLHKPSGAKPGFVTYTGQKTLR
VTPDQAKILSMKLS
>M28_Spy0641 fruR, fructose repressor
MAKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHGGAELFH
SLQEELSNQEKSVKNSHIKKTIAQRASQFIYDNDVIFIDAGTTTEFLLPF
LQAKNLTVVTNSIHHAARLVELSIETIIVGGYVKQTTDASIGNVALEQIR
QMNFDKAFLGMNGIDDSYLTTPDMEEAVIKKAVLSNAKLAYILVDGTKIG
QVSFVKVAPINDVTIITLGGSASILKQIKEKAKVIEL
>M28_Spy1196 glcK, glucokinase
MSQKLLGIDLGGTTIKFGILTAAGEVQEKWAIETNILEGGKHIVPDIIAS
IKHRLDLYGLSSADFVGIGMGSPGAVDRDTNTVTGAFNLNWKETQEVGSV
VEKELGIPFAIDNDANVAALGERWVGAGENNPDVVFMTLGTGVGGGIIAD
GNLIHGVAGAGGEIGHMIVEPENGFACTCGSHGCLETVASATGVVKVARL
LAEAYEGDSAIKAAIDNGEGVTSKDIFMAAEAGDSFADSVVEKVGYYLGL
ASANISNILNPDSVVIGGGVSAAGEFLRSRIEKYFVTFTFPQVRYSTKIK
IAELGNDAGIIGAASLARQFITK
>M28_Spy0285 greA, transcription elongation factor
MFVFLIRSKKKREKTIMAEKTYPMTLTEKEQLEKELEELKLVRRPEIVER
IKIARSYGDLSENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAK
DEVAIGKTVIVQEVGTTDKDTYHIVGAAGADIFSGKISNESPIAQALIGK
KTGDKVRIESPAATYDVEIISVEKTN
>M28_Spy1489 hrcA, heat-inducible transcription repressor
MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDMAKLEKL
GLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKTFDFEAFK
LEDMLQKASHILAEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMT
LDESKPVTVQFAIPRNFLTRDLIAFKAIVEERLLDSSVIDIHYKLRTEIP
QIVQKYFVTTDNVLQLFDYVFSELFLETVFVAGKVNSLTYSDLSTYQFLD
NEQQVAISLRQSLKEGEMASVQVADSQEAALADVSVLTHKFLIPYRGFGL
LSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYRYLNSNHYEVH
>M28_Spy1709 irr, two-component response regulator
MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTTSYDLII
LDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVT
KPFSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTK
KEYDIIDYLAKRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTG
IPLKTITGMGYLLGERE
>M28_Spy1445 lacR.1, lactose phosphotransferase system repressor
MLKRERLLKITEIVNEQGIVTVNDIIQTLNVSDMTVRRDLDELEKAGKLI
RIHGGAQSITMPNKKERSNIEKQTVQTKEKWELASYATQLVNDGETIFIG
PGTTLECFAEQLKNRQIRIVTNSLPVFNILQDSETIDLILIGGEYRSITG
AFVGSLASQNISSLKFAKAFISCNGIYKNDIATYSETEGEIQKLAFNNSI
EKYLLVDNQKFNAYDFFIFYHLNNIDAVVTDSQITEDVIERYSQFTQLLV
AHENKE
>M28_Spy1629 lacR.2, lactose phosphotransferase system repressor
MKKKERHEKILDILKVDGFIKVKDIIDEMNISDMTARRDLDTLADKGLLI
RTHGGAQYLDYSSAKDEGHEKTHTEKKVLQTTEKKQIAQRAKNIIKDGET
VFIGPGTTLEHLAVELKNRNIRVITNSLPVFLILHPSTTIDLILIGGECR
EITGAFVGAIAINNLESLTFSKAFVSANAVYNNSIATYSDLEGEVQRVAL
NNAVEKILLVDSTKFESYDFYNFYQLDQVDLIVTDKNVTTDIIEKYKKFS
KIIIADK
>M28_Spy0455 licT, transcription antiterminator, BglG family
MLIKRVLNHNAAISTNHQGLDILLMGKGIAFGKKVGDSIELNAIETSFVL
KNSDNMNRFTELFITVPQEVVACSERIINLGKIKLGKTLDEILYINLTDH
IHSAIERHEQGMLIHNPLRWEIQRYYPDEYSLGVKALELIERNLGVTLAI
DEAAFIAMHFVNASLDTPFKEPHRLTEIVSYIEQKIKTDFKTELDDTSID
YYRFMTHIKLFAQRVLSEMSYDDDDAELLLVVKTKYPKEYRCVLDISEEI
KKRYNYHLNSSELLYLTVHVKRLVKHLKET
>M28_Spy1463 lytR, transcriptional regulator, LytR family
MKIGKKIVLMFTAIVLTTVLALGVYLTSAYTFSTGELSKTFKDFSTSSKK
SDAIKQTRAFSILLMGVDTGSSERASKWEGNSDSMILVTVNPKTKKTTMT
SLERDTLTTLSGPKNNEMNGVEAKLNAAYAAGGAQMAIMTVQDLLNITID
NYVQINMQGLIDLVNAVGGITVTNEFDFPISIAENEPEYQATVAPGTHKI
NGEQALVYARMRYDDPEGDYGRQKRQREVIQKVLKKILALDSISSYRKIL
SAVSSNMQTNIEISSRTIPSLLGYRDALRTIKTYQLKGEDATLSDGGSYQ
IVTSNHLLEIQNRIRTELGLHKVSQLKTNATVYENLYGSTKSQTVNNNYD
SSGQAPSYSDSHSSYANYSSGVDTGSSYQSASTDQDSTASSHTPTTPSSS
SDALAADESSSSGSGSLVPPANINPQT
>M28_Spy1038 malR, transcriptional regulator, LacI family
MYNGNEIHDKPMIRFIFGKYSNEVNMVTIKDVAQKAGVNPSTVSRVLKDN
RSISMKTKEKVRKAMADLGYVPNVAAQILASGLTHNIGLVFPPITTSDRL
SEPFFMEILSTITNEAKESHFTVSIATGISLDDLIEQVKLMHLQKRVDGF
IILYSDQDDPVKKYLMTNNLPFVIVGAPQGDTNKTTYIDNDNQLMAKTAV
EHLYQKGHHNILFITDDLLSEVTSERYLGYLKGCFKRSLKTKPMLLFDRK
DPVSVEILMETISSFKATALVVVGDVLAIRMVQLLSFYDIKVPDDMSIIT
FNNSNYAKLIHPYLTTFDINVENLGKMSFKQLLDIINSNEQNLSQTIFVP
FSLKQRESVRDISH
>M28_Spy0395 mutR, transcriptional regulator
MKVGKMEKELGKTLRRLRKGKQVSISFLADEYLSKSQISRFERGESEITC
SRLLNLLDKLNITIDEFVSAHSKTHTHFFTLLSQARKCYAEKNVVKLTKL
LKDYAHKDYERTMIKAILFSIDSSIAPSQEELTRLTDYLFKVEQWGYYEI
ILLGNCSRFMNYNTLFLLTKEMVASFAYSEQNKTNKMLVTQLSINCLIIS
IDHSCFEHSRYLINKIDLLLRDELNFYEKTVFLYVHGYYKLKQEEMSGEE
DMRQALQIFKYLGEDSLYYSYKEHYRQIVLGGKGDEDWSEADL
>M28_Spy1455 nusA, N utilization substance protein A
MPSFTSKVDNIMSKEMLEAFRILEEEKHIDKADIIDAVTESLKSAYKRRY
GQSESCVIEFNEKTADFQVFTVREVVEEVFDSRLEISLKDALAISSAYEL
GDKIRFEESVNEFGRVAAQSAKQTIMEKMRRQMREVMFNEYKEHEGEIMT
GTVERFDQRFIYVNLGSLEAQLSHQDQIPGETFKSHDRIDVYVYKVENNP
KGVNVFVSRSHPEFIKRIMEQEIPEVFDGTVEIMSVSREAGDRTKVAVRS
HNPNVDAIGTIVGRGGSNIKKVISKFHPKRVDAKTGLEIPVEENIDVIQW
VDDPAEFIYNAIAPAEVDMVLFDDEDLKRATVVVPDSKLSLAIGRRGQNV
RLAAHLTGYRIDIKSASEYDRLEAEKEAATVVEEPVVDDVMTAEEV
>M28_Spy1532 nusB, N utilization substance protein B
MMRISWMTNSFQNSRRDLRERAFQALFNIEMGAELLAASQFAYGYDKVTG
EDAQVLELPIFLLSLVTGVNNHKEELDNLISTHLKKGWSLERLTLTDKTL
LRLGLFEIKYFDETPDRVALNEIIEVAKKYSDETSAKFINGLLSQYVSEA
PSANKS
>M28_Spy0136 nusG, transcription antitermination protein
MKGNIMLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
TQTVNVEKNGQTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGS
HGNRSKPTPLLEEEIRAILLSMGQTIDVFDTNIKEGDVVQIIDGAFMGQE
GRVVEIENNKVKLMLNMFGSETVAEVELYQIAEL
>M28_Spy1899 parB, chromosome partitioning protein
MFLILSRNSLMTKELLIDLPIEDIVTNPYQPRIQFNQRELQDLATSIKSN
GLIQPIIVRKSDIFGYELVAGERRLKASKMAGLKKVPAIIKKISTLESMQ
QAIVENLQRSNLNAIEEAKAYQLLVEKKHMTHDEIAKYMGKSRPYISNTL
RLLQLPAPIIKAIEEGKISAGHARALLTLSDDKQQLYLTHKIQNEGLSVR
QIEQLVTSTPSSKLSKKTKNIFATSLEKQLAKSLGLSVNMKLTANHSGYL
QISFSNDDELNRIINKLL
>M28_Spy1509 recG, ATP-dependent DNA helicase
MILTAPMSNLKGFGPKSAEKFQKLDIYTVEDLLLYYPFRYEDFKSKSVFD
LVDGEKAVITGLVVTPANVQYYGFKRNRLSFKLRQGEAVLNVSFFNQPYL
ADKIELGQEVAVFGKWDATKSAITGMKVLAQVEDDMQPVYRVAQGISQST
LIKAIKSAFEIDAHLELKENLPATLLEKYRLMGRSQACLAMHFPKDITEY
KQALRRIKFEELFYFQMNLQVLKAENRSETNGLPILYSKHAMETKISSLP
FILTNAQKRSLDDILSDMSSGAHMNRLLQGDVGSGKTVIAGLSMYAAYTA
GFQSALMVPTEILAEQHYISLQELFPDLSIAILTSGMKAAVKRTVLAAIA
NGSVDMIVGTHALIQDSVQYHKLGLVITDEQHRFGVKQRRIFREKGENPD
VLMMTATPIPRTLAITAFGEMDVSIIDELPAGRKPIMTRWVKHEQLGTVL
EWVKGELQKDAQVYVISPLIEESEALDLKNAVALHAELSTYFEGIAKVAL
VHGRMKNDEKDAIMQDFKDKKSHILVSTTVIEVGVNVPNATIMIIMDADR
FGLSQLHQLRGRVGRGYKQSYAVLVANPKTDSGKKRMTIMTETTDGFVLA
ESDLKMRGSGEIFGTRQSGIPEFQVADIVEDYPILEEARKVSAAIVSDPN
WIYEKQWQLVAQNIRKKEVYD
>M28_Spy0496 regR, transcriptional regulator, LacI family
MTNHYYFKGVYAMQRKVTIKDIAELAKTSKTTVSFYLNGRFDKMSEETKN
RIKSTIEATNYKPSIAARSLNAKSTKLIGVVIGDITNSFSNQIVKGIESK
AQEFGYQIIIGNSNYDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRII
DIKKKKVVFFDSQLYEHRTNWVKTNNYDAVYDTIQQCIDKGYEHFIMITG
NPNLLSTRIERASGFIDVLEANHLTHQEMIIDENQTSSEAIAQFLQGSLT
KKSLVFVPNCWALPKVFTAMKSLKFNIPEIGLVGFDNIEWTKFSSPTLTT
IIQPAYEEGEQATKILIDDIEGHSQEAKQQIFDCQVNWQESTF
>M28_Spy1674 relA, GTP pyrophosphokinase
MRNEMAKIMNVTGEEVIALAATYMTKTDVAFVAKALAYATAAHFYQVRKS
GEPYIVHPIQVAGILADLHLDAVTVACGFLHDVVEDTDITLDEIEADFGQ
DARDIVDGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRL
HNMRTLKHLRKDKQERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLN
ETEFYKISHMMKEKRREREALVEAIVSKVKTYTTQQGLFGDVYGRPKHIY
SIYRKMRDKKKRFDQIFDLIAIRCVMETQSDVYAMVGYIHELWRPMPGRF
KDYIAAPKANGYQSIHTTVYGPKGPIEIQIRTKDMHQVAEYGVAAHWAYK
KGVRGKVNQAEQAVGMNWIKELVELQDASNGDAVDFVDSVKEDIFSERIY
VFTPTGAVQELPKESGPIDFAYAIHTQIGEKATGAKVNGRMVPLTAKLKT
GDVVEIITNANSFGPSRDWVKLVKTNKARNKIRQFFKNQDKELSVNKGRD
LLVSYFQEQGYVANKYLDKKRIEAILPKVSVKSEESLYAAVGFGDISPIS
VFNKLTEKERREEERAKAKAEAEELVKGGEVKHENKDVLKVRSENGVIIQ
GASGLLMRIAKCCNPVPGDPIDGYITKGRGIAIHRSDCHNIKSQDGYQER
LIEVEWDLDNSSKDYQAEIDIYGLNRSGLLNDVLQILSNSTKSISTVNAQ
PTKDMKFANIHVSFGIPNLMHLTTVVEKIKAVPDVYSVKRTNG
>M28_Spy1724 rgg, transcriptional regulator
MEIGETVEFIKHSKNISIKQVCGDYLTRQTYYRFIKNNLDISSKKLLYIL
DNLNVNVDEFLFISNNFKQYKEFIDMDTAKHYFECRNIEGLNHILDSYKD
SKSTKEKNLFALVKVLLATLTEEDCLTERTYLSNYLINIETWSHYETVLF
NNCMFIFESCFIEMVFSKVILNLDKYNTLRYYGNESIRMFVNMLILFIQR
QEYDKASEILAKIEDYQLNDDCLYERCCVSFFDGIIGLINGKEGAEQKCV
QILEIFQLLNCKTIHHMFQTYLEAIKHKLS
>M28_Spy0069 rpoA, DNA-directed RNA polymerase alpha chain
MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLSSLPGAA
VTSIKIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELEVE
GPAEVTAGDILTDSDIELVNPDHYLFTIAEGHSLRATMTVAKKRGYVPAE
GNKKDDAPVGTLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNG
TIIPEDALGLSARVLIEHLNLFTDLTEVAKATEVMKETEKVNDEKVLDRT
IEELDLSVRSYNCLKRAGINTVFDLTEKSEPEMMKVRNLGRKSLEEVKVK
LADLGLGLKNDK
>M28_Spy0081 rpoB, DNA-directed RNA polymerase beta chain
MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSGLKEVFE
DVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVN
KETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKV
DKNGKVGYGSTVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALG
FSGDDEIVDIFGESDLVRNTIEKDIHKNPSDSRTDEALKEIYERLRPGEP
KTADSSRSLLIARFFDARRYDLAAVGRYKVNKKLNIKTRLLNQIIAENLV
DAETGEILVEAGTEMTRSVIESIEEHLDGDLNKFVYTPNDYAVVTEPVVL
QKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYFLNLAEGLG
KVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTR
DRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTP
YRKVDRATGRVTNEIVWLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRH
QGNNQEFSASVVDFVDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQ
AVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQHNGKVVFSDAEKVEIRRQD
GSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIADGPSMENGEMA
LGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDTKL
GPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDL
SAEERLLHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSG
VNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVD
IMLNPLGVPSRMNIGQVMELHLGMAARNLGIHIATPVFDGASSEDLWDTV
REAGMDSDAKTVLYDGRTGEPFDNRVSVGVMYMIKLHHMVDDKLHARSVG
PYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDVT
GRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDNEVEL
RDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK
>M28_Spy0082 rpoC, DNA-directed RNA polymerase beta' chain
MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEV
IFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAP
VSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLL
TEREYREKLQEYGHGSFVAKMGAEAIQDLLKRVDLAAEIAELKEELKSAS
GQKRIKAVRRLDVLDAFNKSGNKPEWMVLNILPVIPPDLRPMVQLDGGRF
AASDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNG
RRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPT
LKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVERGDERIWD
ILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGN
YYLTMEDAGREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPW
KDSQRHKIMVTTVGKILFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPG
QDIQEVIDRLDINVPFKKKNLGNIIAETFKRFRTTETSAFLDRLKDLGYY
HSTLAGLTVGIADIPVIDNKAEIIDAAHHRVEEINKAFRRGLMTDDDRYV
AVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNISNFSQLAGMRG
LMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGY
LTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTR
KSVKHPETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVC
RHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTD
ITQGLPRIQEIFEARNPKGEAVITEVKGNVVEIEEDASTRTKKVYVQGKT
GMGEYVVPFTARMKVEVGDEVNRGAALTEGSIQPKRLLEVRDTLSVETYL
LAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGDTDLLPGTLMDIS
DFTDANKDIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETTRVLT
DAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAMNEIEVIDHT
EVSAEAVFTAEAE
>M28_Spy0579 rpoD, RNA polymerase sigma factor
MTKQKEITTFNVQVAEFIRHHKKEGTAIDDDVTEKLVIPFALDADQIDDL
LERLTDGGISITDKEGNPSSKYIVEEPKPEELTDEELIGSNSAKVNDPVR
MYLKEIGVVPLLTSEEEKELAVAVAKGDLMAKQRLAEANLRLVVSIAKRY
VGRGMQFLDLIQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIA
DQARTIRIPVHMVETINKLVREQRNLLQELGQDPTPEQIAERMEMTPDKV
REILKIAQEPVSLETPIGEEDDSHLGDFIEDEVIENPVDYTTRVVLREQL
DEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGKVFNVTRERIRQIEAKA
LRKLRHPSRSKQLRDFIED
>M28_Spy1600 rpoE, DNA-directed RNA polymerase delta chain
MVENDKIRRTALKLDVFAGQEKSELSMIEVARAILEERGRDNEMYFSDLV
NEIQNYLGKSDAGIRHALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEI
DEEIITLEEDEDGAQKRKKKRVNAFMDGDEDAIDYRDDDPEDEDFTEESA
EVEYDEEDPDDEKSEVESYDSELNEIIPEDDFEEVDINEEDEEDEEDEEP
VL
>M28_Spy1615 salR, transcriptional regulatory protein
MKILLIDDHRLFAKSIQLLFQQYDEVDVIDTITSHFNDVTIDLSKYDITL
LDINLTNISKENGLEIAKELIQSTPHLKVVMLTGYVKSIYRERAKKVGAY
GFVDKNIDPKQLISILKKVDSGKKYFEQIESQDYVESLTDQEIAILNLSK
KGFSIKEIEETLQISRRTVFNHLTHIYSKLLVNNKQEAIYKAEQLGYFMD
F
>M28_Spy0356 scaR, iron-dependent repressor
MTPNKEDYLKCIYEIGEQEPKITNKMVAEKMHVSAPAVSEMIKKMISQGW
IVKDKAKGYLLKDKGYALVANLYRKHRLIEVFLIHQLGYNTQEVHQEAEV
LEHTVSDTFIDRLDKILDFPDFCPHGGTIPRYGQPLVEMNTTTLNTITEL
GRFRLSRIHDHFDLIQYLEAHHLSINTELTLTQIDTFAKTYTICYGDKEL
VIPENIAKQLYVTAL
>M28_Spy1526 scrK, fructokinase
MRHGCLDKSLCHHKDKKEQEKGENMGKLYGSIEAGGTKFVCAVGDEEFTV
VDKTQFLTTTPEETIARTIAYFKAFEADLAGMAIGSFGPIDIDPSSETYG
HITTTPKSGWANVDLLGQLSAAFKIPFDVTTDVNSSAYGEVLARPGVESL
VYYTIGTGIGAGAIQHGHFIGGLGHTEAGHTYVMPHPDDMAKGFLGVCPF
HKGCLEGMAAGPSIEARTGVRGERLDQEADVWDIQAFYIAQAALQATMLY
RPQVIVFGGGVMTQEHMVLRVHDKFTTLLSGYLPVPDLTDYIVTPAVADN
GSATLGNFALAKLAAQGK
>M28_Spy1531 scrR, sucrose operon repressor
MVAKLTDVAALAGVSPTTVSRVINQKGYLSQKTVNKVNKAMRELGYKPNN
LARSLQGKSTQLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEH
NPVKEREYLEMLAANQVDGIISSSHNLGIEDYERVEAPIVAFDRNLAPNI
PVISSDNFEGGKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQL
KRSAEIIKLPNNLSPVRREMEIKSILATRKPDGLFVSDDLTAILIMKVAK
QLHITIPEDMKVIGYDGTTFIQQYVPQLATIRQPIDEIAKLSVEILIKKI
KKEKTSKDYILPITLLPGASI
>M28_Spy0280 snf, phage-related DNA helicase
MMARLIPGRVRNEGIKLYEQGLVSFQDDNKGILQIEVETYQVQYGADDED
ITCQCDTFHMKHYCKHIAAVEYFLKNDQKGKLFLKQLTNQTKIKETTKKM
TSFGSLFLDSLAMNEDDSVKYRLSALGSRSPFSSDYWWSLKINRLPDDRS
YVIRDIKGFLQLIKKEGFYQIGKNYFEQLSWLQFDPSSQDLIEFLWRLAS
NTDKGDNENIFPNHARHLRLPSGFFEEGIHYLTSLYDFTFEGPSQTYHHL
FVRSLEAEAGLYEFKVEVHRKSIELQIAEKNVQYLFDNDYLLYQDTFYHL
TLKQRKMVQAIRSLPIEADLAKHIHFDLDDHAKLAASLSDFKQIGLVEAP
KSFAIRDFEVTFQFDLLNRDEISCQLMFDYGNYQVSDKASLEALPFASHL
KKEEKINRSLLAFGFSPQFYSKKRLTSAKELYTFFEETVPCFERLGNVAL
STAIQALQVKEMPKIAIRRNQGLLDISFDFSTIIENDIDQAVTALFQNNP
YFVSQTGQLVVFDDETQKVSKSLQELRARQLKNGHLQLDGIRALQVSKLF
EGMTSVHFSKELEELAYHLQHPETFSIKPLPVKAQMRDYQRNGVQWLSML
NHYGFGGILADDMGLGKTLQTLAFLASHLKSDSKVLILSPSSLIYNWFDE
CQKFTPQLDVVVSYGLKQIRDQIIEEGHQITITSYSSFRQDFETYQAFHY
DYLILDEAQVIKNAQTKISHCLRAFNTANCFALSGTPIENKMLEIWSIFQ
IVLPGLLPTKKEFLKLTAEQVSRYIKPFVMRRKKEDVLPELPDLIETNYS
NEMTDEQKAIYLAQLRQMKDQIRNSSDVDISRQKIEILSGITRLRQICDT
PSLFMDYQGKSGKLDSLRILLTQIKENGHRALIFSQFRGMLDLAKQEMTA
LGLTSYQMTGSTPANERQEMTRAFNNGSKDAFLISLKAGGVGINLTGADT
VILIDLWWNPAVEMQAISRAYRIGQKENVEVYRLITRGTIEEKILELQES
KRNLVTTVLDGNENRASMSIEEIKEILGLNTH
>M28_Spy0779 srtR, two-component response regulator
MYKILAIDDDKEILKLMKTALEIENYHVITCQEIELPIVFDDFKGYDLIL
LDIMMPNISGTEFCYKIREEVHSPIIFVSALDGDNEIVQALNIGGDDFIV
KPFSLKQFVAKVNSHLKREERAKIKNEAEERVKRSFPPIEIYLEERMLYI
DKQPLFLTYREYEILELLSRHPYKVFTKEEIYEQVYSDEASALFHSISEY
IYQIRMKFSSFGINPIKTIRGIGYKWDV
>M28_Spy0006 trcF, transcription-repair coupling factor
MNILELFSQNKKVQSWHSGLTTLGRQLVMGLSGSSKALAIASAYLDDQKK
IVVVTSTQNEVEKLASDLSSLLDEELVFQFFADDVAAAEFIFASMDKALS
RIETLQFLGNPKSQGVLIVSLSGLRTLLPNPDVFTKSQIQLTVGEDYDSD
TLTKQLMTIGYQKVSQVISPGEFSRRGDILDIYEITQELPYRLEFFGDDI
DSIRQFHPETQKSFEQLEGVFINPASDLIFEASDFQRGIEQLEKALQTAQ
DDKKSYLEDVLAVSKNGFKHKDIRKFQSLFYEKEWSLLDYIPKGTPIFFD
DFQKLVDKNARFDLEIANLLTEDLQQGKALSNLNYFADNYRELRHYKPAT
FFSNFHKGLGNIKFDQMHQLTQYAMQEFFNQFPLLIDEIKRYQKNQTTVI
VQVESQYAYKRLEKSFQDYQFRLPLVSANQIVSRESQIVIGAISSGFYFA
DEKLALITEREIYHKKIKRRARRSNISNAERLKDYNELAVGDYVVHNVHG
IGRFLGIETIQIQGIHRDYVTIQYQNSDRISLPIDQIGSLSKYVSADGKE
PKINKLNDGRFQKTKQKVARQVEDIADDLLKLYAERSQQKGFSFSPDDDL
QRAFDDDFAFVETEDQLRSIKEIKADMESMQPMDRLLVGDVGFGKTEVAM
RAAFKAVNDHKQVAVLVPTTVLAQQHYENFKARFENYPVEVDVLSRFRSK
KEQAETLERVRKGQIDIIIGTHRLLSKDVVFSDLGLIVIDEEQRFGVKHK
ETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQTY
VLENNPGLVREAIIREMDRGGQIFYVYNKVDTIEKKVSELQELVPEASIG
FVHGQMSEIQLENTLIDFINGDYDVLVATTIIETGVDISNVNTLFIENAD
HMGLSTLYQLRGRVGRSNRIAYAYLMYRPDKVLTEVSEKRLEAIKGFTEL
GSGFKIAMRDLSIRGAGNILGASQSGFIDSVGFEMYSQLLEQAIASKQGK
TTVRQKGNTEINLQIDAYLPDDYISDERQKIDIYKRIREIQSREDYLNLQ
DELIDRFGEYPDQVAYLLEIALLKHYMDNAFAELVERKNNQVIVRFEVTS
LTYFLTQDYFEALSKTHLKAKISEHQGKIDIVFDVRHQKDYRILEELMLF
GERLSEIKIRKNNSVFK
>M28_Spy0423 vicR, two-component response regulator
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLII
LDLMLPELDGLEVAKEIRKTSHVPIIMLSAKDSEFDKVIGLEIGADDYVT
KPFSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAF
VAKKHGQEVELTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRT
VDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD
>M28_Spy1373 yvqC, two-component response regulator
MTMSKIKVILVDDHEMVRMGLKSFLNLQADIDVVGEASNGREGVDLALAL
KPDVLVMDLVMPELGGVEATLEVLKKWKEAKVLVLTSYLDNEKIYPVIDA
GAKGYMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEEL
TAREYDILHLLAKGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQA
VVYAFRHHLVPQDDN