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# Streptococcus pyogenes phage 5005.3

>M5005_Spy1061 transcriptional regulator, LacI family
MMTSKITIKDIAREAGVSVATVSYVLNQRNDQKISEETRNKVLHISNLLN
YTPNQAARSLVTQQSNSVVLYYKYADSILARAEQLHTISFLSRLLHEQDY
QLVCLNEDSTEKFDWADLILTLDVDNDTFYKIGKLNFKPLIAIDSFVNDP
LFFQINTDYAALKDQANQFFKDEPYTLLSLPITNRERYEHVSAFFPSLHI
VNDLRELTYFEKENLLLIDESLDQFFVNSSQKLCCPRFSPKKGQVILETI
EWAKKRQPDKKHNLLV
>M5005_Spy1411 hypothetical cytosolic protein
MSKVKKIPLRKSLVSGEIIAKRDLLRIVKTKDGQVFIDPTGKQNGRGAYI
KLDNQEALMAKKKQVFNRSFSMDIPESFYDDLIAYVDHKIKRRELGLD
>M5005_Spy0309 hypothetical cytosolic protein
MTYLSQIEALLFVAGEEGLSLRHLASMLSLTPTALQQQLEKLSQKYEKDQ
HSSLCLIETANTYRLVTKEGFAELLRAYAKTPMNQSLSRASLEVLSIVAY
KQPITRIEIDDIRGVNSSGALSKLLAFDLIREAGKKDVVGRPHLYATTDY
FLDYMGINHLDELIEVSAVEPADEEIALFRTQD
>M5005_Spy1274 acetyltransferase
MADKFDANDETRTVYAVVYDNDQPVSTGQFLAETKIEARLTRIVTLADYC
GCGYGAKVTEALETYTRREGFYQLTIHSELTAQTFYENLGYQSYGPKCLE
DGEYCQSLAKTILKWEKNMDIAMLIAIVGGLLGCYLYLTKNN
>M5005_Spy1104 cytosolic protein containing multiple CBS domains
MSKHQDILDYLEKLAIGKKVSVRSISNHLKVSDGTAYRAIKEAENRGIVE
TKPRSGTVRIEKKGRVRIDRLTYSEIARISDSEVLAGHAGLGHEFSRFSI
GAMTQQNIRRYLVKGGLLIVGDRETIQLLALENHNAILVTGGFPVSKRVI
EMANNQRIPVMVTHYDTFTVATMINHALSNIRIKTDLKTVEQVMIPITDY
GYLCEDSSVEEFNTLIKKTRQVRFPVLDYKRKVIGVVSMRDVVDQLPTTK
LTKVMSKNPITARPNTSLANISQKMIFEDLNMLPVTDEENNLLGMITRRQ
AMENLPNHQPNNPYTYSEQILSNLEETVDYYQVVVEPTMIDSAGNMSNGV
ISEFLKEISIRALTKKHQKNIIIEQMMVYFLHAIQIEDELKIYPKIITEN
RRSSTIDIEIFVDDQVIAKAIITTKIN
>M5005_Spy1364 ATP-dependent RNA helicase
MSFKDYHFKQYVQQALEEIGFVNPTEVQKRLIPIVNSGRDLVGESKTGSG
KTHTFLLPIFEKLDEAKAEVQVVITAPSRELATQIFDACKQIAKHFQEEI
RLANYVGGTDKLRQIEKLKDSQPHIVIGTPGRIYDLVKSGDLAIHKATTF
VVDEADMTMDMGFLDTVDKIAASLPKSVQILVFSATIPQKLQPFLKKYLT
NPVIEQIKTKTVIADTIDNWLVSTKGRDKNGQLLEILKTMQPYMAMLFVN
TKERADDLHAFLTANGLKVAKIHGGIPPRERKRIMNQVKKLDFEYIVATD
LAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTGRNGMAGTAITLYQPSD
DSDIKELEKMGIAFTPKVLKNGEFQDTYDRDRRQNREKAYQKLDTEMIGL
VKKKKKKVKPGYKKKIQWAVDEKRRKERRAENRAKGRAERKAKKQHF
>M5005_Spy1648 transcriptional regulator, Cro/CI family
MKNLKLKAARAGKDLSQQALADLVGVSRQTIAAVEKGDYNPTINLCIAIC
RVLDKTLDDLFWEADDSR
>M5005_Spy0164 parB-like nuclease
MSNFISPVYEIKSIPIEKISPNDYNPNSVAPPEMKLLYDSIKSDGYTMPI
VCYYDKEEDRYSIVDGFHRYRIMLDYSDIYERESGRLPVSVIDKSLDYRM
ASTIRHNRARGSHDVDLMSQIVKDLHECGRSDNWIAKHLGMDKDEILRLK
QITGLASLFKDHEFNQSWEPEELLNE
>M5005_Spy0118 transcriptional regulator, LysR family
MNISSLAYFIEIVNCDFNLTKAAQKSHISQPALSSYIKTIEKEEGVVLFQ
RQKGRLVGLTSVGERFFENAKVVIASHEQLMADLRSESKKYKGEISIGIP
QLISGIVFSELIPKLIEENPEVKFHIVETGAYELQKNCF
>M5005_Spy1265 ribose operon repressor
MRLKNPHKLILQGGKAMVTIKQVAEEAGVSRSTVSRYISQKGYVSDDARH
KIKAAIAKLHYTPNVLAQSLKTKKIN
>M5005_Spy0924 transcriptional regulator, GntR family
MTTKYQTIISNIEQDIQKQRLKKGDKLPSIRVLSKVYYCSKDTVQRALLE
LKYRHLIYAVPKSGYYVLGNVSMPDNVLNLSLEDYNNMAYEDFRLCLNEA
LSAKDKYLFHYYHKTEGLEELREALLLYLAENSVYSNKDQLLITSGTQQA
LYILSQMPFPNTGKTILLEKPTYHRMEAIVAQLGLPYQTISRHFNGLDLE
LLESLFQTGDIKFFYTISRFSHPLGLSYSTKEKEAIVRLAQRYQVYILED
DYLGDFVKLKEPPIHYYDTHHRIIYLKSFSMSVFPALRIGALVLPSGLKP
HFLTQKSLIDLDTNLLMQKALALYLENGMFQKNLRFIKRYLKQRERQLAL
FLKQNCPDIHYQLTPTHLVIDYTTSDSYRNFTLDKSDRIIITGKKRYLSI
TINQQIQSKLNSLIKNTCGKSN
>M5005_Spy1785 trehalose operon transcriptional repressor
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLL
TKAGLILKKQGRGTQVIRHHQIMFPISELTSYQELVSYSNLDSKTNVIAI
DKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIM
TREIAEHSIYQYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVV
SVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRPK
>M5005_Spy1464 phage transcriptional regulator, Cro/CI family
MLFYRYFLSSHRKADKSMFSTFERIKELAKSRGISLGLLEEKLGLSRNSI
YTIKNKKPSAERLQLIADYFHVSTDYLLGRTDNPKIAQDGHASVAIDLKK
DAEETFFFDGHELNDEDIDLITSILETRIKNRK
>M5005_Spy0888 transcriptional regulator, LysR family
MDIRQLTYFIAVAETKNHSHAAKSLFVTQPTLSQSIKRLES
>M5005_Spy0929 SIR2 family protein
MSNWTTYPQKNLTQAEQLAQLIKEADALVVGIGAGMSAADGFTYIGSRFE
TAFPDFIAKYQFLDMLQASLFDFEDWQEYWAFQSRFVALNYLDQPVGQSY
LDLKEILGTKDYHIITTNADNAFWVAGYDPHNIFHIQGEYGLWQCSQHCH
QQTYKDDTVIRQMIAEQKNMKVPGQLIPHCPECEAPFEINKRNEEKGMVE
DADFHAQKARYEAFLSEHKEGKVLYLEIGVGHTTPQFIKHPFWKRVSENP
NALFVTLNHKHYRIPLSIRRQSLELTEHIAQLISATKTIYQKS
>M5005_Spy1558 transcriptional regulator
MEIGQQIIRYRKQQALSQEKLAEKVYVSRQSISNWENDKTYPDIHSLLLL
SQIFQVSLDQLIKGDIEKMKYTITQVDKKNFKRDTKVMVTLMILLMISSY
PLVYFLEWLGLGIFVLLSIITMTYANRVERFKKKYDVQPYKEILAVSNGK
LLDEIEKREERATLPYQKPLIVTVFFLITVAFAFASRFMFTWLFH
>M5005_Spy1786 transcriptional regulator, MarR family
MEADGLVHREVYAEVPPRVEYSLTETGLSLAPVIEAMSDWGQTYQEKHAD
LFEEG
>M5005_Spy1583 hypothetical cytosolic protein
MGIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNEKGVTVVKRSGLVK
LEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDAQL
ASKDEQMRVKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEAN
QARLQVEEVQAEVGPKKGFFTRLFAK
>M5005_Spy0680 two-component response regulator
MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNAYDIMIL
DIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLT
KPFSLKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLA
SKEGKLMAFLMLNQGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKL
LAIQANVIIAGDKDTSYCLLEK
>M5005_Spy1495 transcriptional regulator,MarR family
MEYDKINQYLVDIFNRILVIEEMSLKTSQFSDVSLKEMHTIEIIGKYDQV
TPSDIARELMVTLGTVTTSLNKLEAKGYIARTRSRSDRRVVYLSLTKRGR
LLDRLHAKFHKNMVGHVIADMSDEEMQALVRGLGNLHQFLEDLV
>M5005_Spy1131 transcriptional regulator, Cro/CI family
MAMEVILKNRLKELRARDGINQTEMAKLAGVSRQTISLIERNEYTPSVII
AMKIAKVFQEPVEEVFRLVEVEE
>M5005_Spy0886 transcriptional regulator, LysR family
MSQGKIDIGLLSFLSIRKDITIELLQTSTKGYKVSIVLLKQHPLAQHPQL
KLKDLKGYKIASLNDHYMLGEMLPRKCRALGFEPDIVFKHNDWEVLIHSL
HDLNTLTILPSDFESLNQVDNLVWIPLQDKNNFYPIGIAYRDDASFSPVI
EEFLSLLKTN
>M5005_Spy1343 transcriptional regulators, LysR family
MDIKQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEKRENVKLFK
RKRGRIIGLTYLGDNYYKDAQKVLSLYDDMFLKLHDHSKGLKGSINIGIP
PLILSVVFSEVMPKLILENPGIQFNVKEIGAYQLKNELLVGNVDVAVLLS
PTGIADNLVETYEIQRSELSVCLSPRHRLASKKVIQWEDLTDEQLALFDP
SFTVHHLVLEACERHQVRPNIILTSSSWDFMLNSTKINHNVLTICPKPIT
ELYQLKDIKCIPMERPISWRVVLTRLRKKSYSEIEAYIMDDLLQSFFK
>M5005_Spy0284 putative regulatory protein
MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERVEELPLL
VIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENVISRIEQEVRTTYE
NEVSSTAIGNLVMDELAELDEITYVRFASVYKSFKDVDEIEELLQQITNR
VRGKKKRLNNDETN
>M5005_Spy0155 transcription antiterminator, BglG family
MMILDKKSYDLLSYLLKLETPETVMAISHALNQSRRKVYYQLDKINQALP
KGVDQIISYPRLGILLTADQKAACRLLLEEVTDYNYVMKSDERRRLSSIY
IAVSTERVTIDKLMQINDVSRNTILNDLTELREELEDKQYKIQLHATKAR
GYYFGCHPMALIQYLYKLLVDVYQGGNTSFIDIFNRKLSEIQGLSVYFSK
DILTYFHEYLFLSQASLGKTINTQDSQFMLQILPFMLLSYRNMRLDSETK
SALKQEFHLIWKRKEYHIAQDLARELYHNFKLHLDDIEVSMVAMLMLSFR
KDQDHHVESQDYDDMRATISHFIDQLESRYQLHFTHKQDLLKQLTTHCKA
LVYRKAYGIFLVNPLTDHIKEKYEELFAMTQSCATILEQDWTISLTDDDI
AYLTIHLGGELRHNNTEQEKTKLVIVSDDGIGIQKLLFKQCQRYLANGQI
EAVFTTEQYQSVYDLLAVDMIVATTDTLKTKIPMLIVNPILSDDDIIKLI
RFSKQGRLSEHSRFSTELTKAIEAVVKDESDRYALVSKIEKLIHRELL
>M5005_Spy1700 acetyltransferase
MKIIEYKGNYRDDLIFMVLEAKNALRRIPSINPDLLTIETSYLEKEDCFW
LAVNEESRVIGSIAYSSIPKTNEVFLHRLFIKPSLKHQGIGSQLLAFAED
YLRKIGKSHVRIHLGQPKEQWFESYRFYPKHGYQFYDDTHLIKKLI
>M5005_Spy0219 transcriptional regulator, RpiR family
MPKNHRLITKIEASLEHMTSLEKGIAHFFITTDLTPQELTASEIVKRLHI
SQAALTRFAKKCGFTGYRAFAFDYLHSLQESQETFQSIHLELTKRVLMDY
DALINKTYELVNEEKLLNLAKLIDSSERVYFFGKGSSGLVAREMKLRFMR
LGLICDAYSDTDGFTWANSLVNENCLVFGFSLSGKTNSVITALHQASQRG
AKTVLLTTDNQTEFDDSLDIIPVSSTHQLHYGNRVSPQFPLLIMMDIIYA
YVLAIDKPHKEKIFKNTIIDKENNDL
>M5005_Spy1340 DNA-directed RNA polymerase omega chain
MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGATPTQEFKSVKSTLQA
LEEIESGNVVIHPDPSAKREAVRAKIEAERLAKEEEERKIKEQIAKEKEE
EGEKI
>M5005_Spy0654 transcriptional regulator, TetR family
MTKDRQIKKTKTAIYSAFIALLQKKEYSKITVRDMITLANVGRSTFYAHY
ESKEMLLKELCEELFHHLFRQKRNVTFEDYLVHILKHFEQNKDSIATLLL
SNDPYFLLRFKNELEHDVYPNLRCKYIDKTTIPEVFLKQFVLSSFIETLK
WWLHQRQRMSANELLKYYLELIK
>M5005_Spy1311 glucokinase
MSLLCIDIGGTSLKFALCHNGQLSQQSSFPTPSSLEKFYQLLDQEVARYS
AYHFSGIAISSPGAVNKEKGVIEGASAIPYIHHFKIQEALEERLHYPISI
ENDANCAALAEATLGAGKGASSLAMLVLGTGVGGSLVIDGKIYHGAHLFG
GEFGFMIMNDRYQTFSQLGTVVNMAKRYSAIVNNGKDYTGKAVLALAEQG
DPLALKERQVFLQSLAIGIFNIQHAFDPQLILIGGGVSQADFLLSAIEAE
LDKLYQAVEISDLRPQLAICHFKNEANLLGAAIDFYQEHKEA
>M5005_Spy1825 transcriptional regulator, PadR family
MYFPVSATLIEFLILAIVEKNDSYGYDISQTIKLVANIKESTLYPILKKL
EKAGFLTTYSQEHQGRKRKYYAVTSSGRAQLIFLKKEWQSYKFALDGIIE
GSLRHDKD
>M5005_Spy1597 transcriptional regulator, MerR family
MKEKELRRSMAVFPIGTVMTLTDLSARQIRYYEDQGLIKPERTQGNRRMF
SLNDMDRLLEIKDFLSEGLNIAAIKREYVERQGKLMQKQKALTDADVRRI
LHDEMLTQSGFSTPSQHIGNFRI
>M5005_Spy1671 transcriptional regulator, MarR family
MSHLDKNTALKAMVVFRKAQRTLDAFGADIFKKADLTATQFSVLKVLYTK
GCMRINHLIDSLLATSGNMTVVLNNMERNGWISKCKDKTDKRAYVVTLTD
KGTRLIEAVLPKHVARVEEAFAVLTEKEQLCLIELLKKFKQL
>M5005_Spy0414 exoribonuclease II
MKERIMTYLKEHGKSNVNDLAAALEMAGAKHFPSLIKTISKMESQSLLRF
SDDGSLALRKEREKKKEPTVQGVFRANKAGFGFLHVDENEDDMFIGRNDV
GYAIDGDTVEVVVKKPADRLKGTAAEAKVVAIVDRSLKTAVGTFILDDDK
PKYAGYIRSKNQKIQQKIYIKKEPVVLKGTEIIKVDIDKYPIRGHDYFVA
SVRDIVGHQGDVGIDVLEVLESMDIVSEFPAEVLAEANAISEAPTAKDLI
GRVDLRQETTITIDGADAKDLDDAIHIKLLDNGNYELGVHIADVSYYVTE
GSALDKEAIARGTSVYVTDRVVPMLPERLSNGICSLNPNIDRLTQSALME
INSQGHVVNYQICQSVIKTTYRMTYSTVNDMIAGDEEALQEFASIADDVT
LMVALHRILEAMRSKRGALNFDTQEAKIIVNDKGMPVDVVLRQRGIAERM
IESFMLAANECVAEHFAKAKLPFIYRIHEEPKAEKLQQFIDYASTFGIHI
QGTANKISQEALQAFMAKVEGQPGAEVLNMMLLRSMQQARYSEHNHGHYG
LAAEYYTHFTSPIRRYPDLLVHRMVREYNQPSQEKRDHFAQIIPELATSS
SQLERRAIDAERVVEAMKKAEYMAEYVGEEFDGIVSSVVKFGFFVELPNT
IEGLVHITSLPEYYHFNERTLSLQGEKSGKVFKVGQPIRVKLVKADKETG
DIDFEYLPSDFDVVEKIKMSDKASRRDRRKSSKSSKGTKKKEPKEVAKAK
TKGKTKKGSKKPFYKEQAKKKSRKRS
>M5005_Spy1579 transcriptional regulator
MSAKKTFFASNLKYLRLKKNMEQLELANLLGRKSSSSISEWEKGKYTPKS
GLLSDIAAIFDVSLTALMEEDLTLENKGVSYQLPQRELAMISEQLSENNY
TKWVDFAQILLEQQAKEDRELDNH
>M5005_Spy0480 transcription accessory protein
MENNNNHNIAEALSVSLHQIEQVLALTAQGNTIPFIARYRKEVTGNLDEV
VIKSIIDMDKSLTTLNERKATILAKIEEQGKLTDQLRTSIEATEKLADLE
ELYLPYKEKRRTKATIAREAGLFPLARLILQNAQNLETAAEPFVTEGFAS
PQEALAGAVDILVEAMSEDAKLRSWTYNEIWQYSRLVSTLKDEQLDEKKV
FQIYYDFSDQVSNMQGYRTLALNRGEKLGILKVSFEHNLEKMQRFFSVRF
KETNPYIEEVINQTIKKKIVPAMERRVRSELSDAAEDGAIHLFSENLRHL
LLVSPLKGKMVLGFDPAFRTGAKLAIVDQTGKLLTTQVIYPVAPASQTKI
QAAKETLTQLIETYQIDIIAIGNGTASRESEAFVADVLKDFPNTSYVIVN
ESGASVYSASELARHEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIG
VGQYQHDVSQKKLSENLGFVVDTVVNQVGVNVNTASPSLLAHVSGLNKTI
SENIVKYREENGALTSRADIKKVPRLGAKAFEQAAGFLRIPGAKNILDNT
GVHPESYPAVKELFKVLGIQDLDDAAKATLAAVQVPQMAETLAIGQETLK
DIIADLLKPGRDLRDDFEAPILRQDILDLKDLEIGQKLEGTVRNVVDFGA
FVDIGVHEDGLIHISEMSKTFVNHPSQVVSVGDLVTVWVSKIDLDRHKVN
LSLLPPRDTH
>M5005_Spy0811 transcriptional regulator, Cro/CI family
MYPRIRNLREDNDFTQKFVANLLSFSHANYAKIERGEVALMADVLVQFYK
LYNVSIDYLLGQTDYPYRFHNK
>M5005_Spy0195 transcriptional regulator, MarR family
MSQVIGDLRELIHQIEQISDEIAKKYDVEHLAGPQGYVLVFLAKHQNQEI
FVKDIEKQLRISKSVASHLVKRMVKNGFINVMPSQVDKRYKQVVLAQVGR
DKLPLLRECRKDIEHYFLKEITKEELLTAKKVIEQLKQNMLTYKGDNDA
>M5005_Spy0117 transcriptional regulator, LysR family
MSHKTFQETFDSNPNISIKALHRQNLVTFDKTFMINHQLTTLFEEANSLP
VVKCYSASWDFLLNCTRYSSYLTILPRPITHFAHMDGLVEVQLTEHPKWE
VVLASLKHNKTSHLKHYIKHTILDYFMNQRF
>M5005_Spy1219 phage transcriptional regulator, Cro/CI family
MFITFERIKELAKKQGLSINSLEEKMGYSRNTIYALKRNKPGSEKLQEIA
DYFHVSTDYLLGRTDNPAIAKDNQEYTSEDLRKMAKNAKTFDGKPLTESD
IEAIQNIIEIYLKGR
>M5005_Spy0970 NAD-dependent K+ or Na+ uptake system component
MISPKKEITSSKYQKIAISVAQRIANGEYEVGEKLKSRTTIASTFNVSPE
TARKGLNILADLKILTLKHGSGAIVLSKERAIEFINQYESTHSIAVLKEK
IRETINDQGKAMEKMAVLVNDFLMQSQSVSKQYPLAPYEIICNQDSEHFG
KSIGVLNIWHQTGATIVAIEHAGQFIVSPGPYSVIEKGDHIYFVGDESVI
SRMKTFFNLRKGL
>M5005_Spy0107 fibronectin-binding protein
MRGEKMKKTRFPNKLNTLNTQRVLSKNSKRFTVTLVGVFLMIFALVTSMV
GAKTVFGLVESSTPNAINPDSSSEYRWYGYESYVRGHPYYKQFRVAHDLR
VNLEGSRSYQVYCFNLKKAFPLGSDSSVKKWYKKHDGISTKFEDYAISPR
ITGDELNQKLRAVMYNGHPQNANGIMEGLEPLNAIRVTQEAVWYYSDNAP
ISNPDESFKRESESNLVSTSQLSLMRQALKQLIDPNLATKMPKQVPDDFQ
LSIFESEDKGDKYNKGYQNLLSGGLVPTKPPTPGDPPMPPNQPQTTSVLI
RKYAIGDYSKLLEGATLQLTGDNVNSFQARVFSSNDIGERIELSDGTYTL
TELNSPAGYSIAEPITFKVEAGKVYTIIDGKQIENPNKEIVEPYSVEAYN
DFEEFSVLTTQNYAKFYYAKNKNGSSQVVYCFNADLKSPPDSEDGGKTMT
PDFTTGEVKYTHIAGRDLFKYTVKPRDTDPDTFLKHIKKVIEKGYREKGQ
AIEYSGLTETQLRAATQLAIYYFTDSAELDKDKLKDYHGFGDMNDSTLAV
AKILVEYAQDSNPPQLTDLDFFIPNNNKYQSLIGTQWHPEDLVDIIRMED
KKEVIPVTHNLTLRKTVTGLAGDRTKDFHFEIELKNNKQELLSQTVKTDK
TNLEFKDGKATINLKHGESLTLQGLPEGYSYLVKETDSEGYKVKVNSQEV
ANATVSKTGITSDETLAFENNKEPVVPTGVDQKINGYLALIVIAGISLGI
WGIHTIRIRKHD
>M5005_Spy0440 transcriptional regulator
MKSKLGATLRKVRKGKQISLCFVADEHLSKSQISRFERGESEISCIRLIN
ILDKLHITLDEFLILHDEDYTNSETFANLVQYIRKQYSSQNINNIACLLS
DTSDYTLNSFEKTMVKSILHTMDSSIIPSDDELLQLTDYLFKVEKWGYYE
ILLLGNCVRTINYNSYFLLTKEMLNNYIYSSRNKTNKRIVTQLAINCFIL
SINKEEFSNCSYLIDEIKTLLDNELNFYEQTVFLYATGYFEFKRQLETGV
EKMKQAIQVLDILNEDKLKLHYADHFDKLVNKD
>M5005_Spy1264 ribose operon repressor
MLGNISDSEALEEEYVHVLLQSNAAGIITTHDFTKRYPTLAIPVVVVDRV
DQETQYGVFSDNRTGGLLAAQTVWQAGAKEVLLIRGPLDNAENINERFEA
SFSYLQKQDVTMYVCDSQNFDFESIQLEASYNLKCYPTIDSIIAPSDIHA
IAYIHELHSQGKKIPQDVQIIGYDDILMSQFIYPSLSTIHQSSYLMGRYA
AELVYTIASQLTVKANRIKLPVHYVERETIRKR
>M5005_Spy1045 transcriptional regulator
MTRFAIQRLREEKKMSQEELANKSGVSRTTISLIETDKSTTVKLSTLQKL
AVALDVPIGYFFKHNV
>M5005_Spy0218 N-acetylmannosamine kinase
MKHYLAIDIGGTAIKYGLISETGDLLEKEEMATEAYKGGPSILEKVKGLV
KTYQDQMDLAGVAISSAGMVNPDEGEIFYAGPQIPNYAGTQFKKEIEETF
GLPCEVENDVNCAGLAEAISGSAKDYPVALCLTIGTGIGGCLLFNSQVFH
GSSHSACEVGYLHLSDGQFQDLASTTALVQEVVLAYGDDISQWDGRRIFE
QAKAGDAICIAAISKQVDYLGQGIANICYVVNPNVVVLGGGIMAQKDYLA
DKLKTALDSYLVSSLAKKTQLKFASHGNNAGILGAYYHFKQKNERSCSFI
TLEKIENNLASS
>M5005_Spy1099 transcriptional regulator, LytR family
MTKYPMGGLSHHEELRYFYLLRNLSYLSENEKKEFAFLKSKLEIGRAYAP
SKQHYRKSKRQEPYFEDDYYNDYSPNDLLEDDDVNHDSSFVPYGLPIYPK
EDRYLNKKTKLTARRPIDAPQPIDEDDAFLTESVARCALPRSQKRKHKKK
GCMKWFFNILGLLLMTVLMGLGLMFAKGVFDISTNKANYKPAVSQAFDGQ
ETQDGTNILILGSDQRVTQGSTDARTDTIMVVNVGNHAKKIKMVSFMRDT
LINIPGYSYNDNSYDLKLNSAFNLGEQEDHHGAEYVRRALKHNFDIDIKY
YVMVDFETFAEAIDTLFPNGVKIDAKFATVGGVAVDSVEVPDDLRMKNGV
VPNQTIEVGEQRMDGRTLLNYARFRKDDEGDFGRTVRQQQVMSAVMSQIK
DPTKLFTGSAAIGKIYALTSTNVSFPFVVKNGVSVLGSGKNGVEHVTIPE
NGDWVDEYDMYGGQALYIDFDKYQKTLAKLGLR
>M5005_Spy1315 transcriptional regulator, GntR family
MTKLLYKKIYHFIKEQIASGRLQIGDRLPTEKELSEQFSVSRITSKRALV
ELEQEGLITRSRGKGSFVAKKQVTSPEANKDLLLILPFASDYELGDYAKG
IMTSIAETGYRLMVQLASTVRLDTLSDYAGIIYYPEDVNHSIDFLFYCDH
HHIPLVLLDKSLDLFQFPSVVADNKGGACQLTQHLIEQGCDQISFVATGS
FGEVSSVRDRYLGYLAAMAESSLKSHYFPKTETETTDAYLDRLVKTLSET
TATKRGLVVENDWLAIQLIQKITQVGLSIPDQVAIVGFDNSQASRLLSPK
LSTAAQDFYQMGQEAAKVLLQIIHEPDQAVVSCQLPVQVFIRESSH
>M5005_Spy0544 transcriptional regulator, GntR family
MPKEQPLYLQIVDDLEVKIKKSMTENDKLLSERELSDLYGVSRITIRLTL
KELELRDLIYKKQGKGTYVSGIKEPATDLSSTYSFTEQMKKMGKTPKTEI
LSFEQYQVTPYLSGLLELDPDTEVFELERLRIADDMPLMFERSYIPAQPF
QGLSIADLKRKALYDIFAKDYQETIRLAEEEFYASIALDYEAGLLGIKKG
DPVLHIIRKTYNDKNILIELTFSIARADQFRYRVQHHPNG
>M5005_Spy1748 transcriptional regulator, DeoR family
MMNRLERIIQLVSQKKKIDVNSLSEQLDVSKVTIRKDLDKLESKGLLRRE
HGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCAL
LAEVLCQTKRNIKVITNSCFIANYIRQYSSCQIILLGGYYQPNSEVTVGP
LLKEMISLFHVNRVFVGTDGFNKDLGFMGKDMMRSEGVRYMADAAEEVVI
LTDSSKFSKTSLVHQLSLADVNRVITDQALDKQTQELLSASGLVLDFVS
>M5005_Spy0034 transcriptional regulator
MLEHFGGKVKVLRLEKRISREDLCGDESELSVRQLARIELGQSIPSLSKV
IFIAKALNVSVGYLTDGADLELPKRYKELKYLILRTPTYMDDGKLQVREE
QFDEIFEDYYDKLPEEEKIIIDCLQATLDTLLSENTNFGIDLLQEYFNQI
KTKVRFRQNDLILLELYLAYLDIEGMDGQYSDKIFYDSLLDNLSEQFEQF
ELDELFIVNKIIIDISSLSLKNNRLDNLEKAIEMSQKIMAKIQDWNRMPI
LKLIEWKYFLIKQKDIIKAEQSFMKACLFAQMTADQYLENKLIQEWEKDV
KSY
>M5005_Spy1819 hypothetical phage protein
MKFFEENYSQEIPTRIKNLRKKHNITQSELGNAGQVSQVESGKRPITSSM
LVYLNALTASNYTYIVFGELDEFIENLFHYFFSSILYRDLEAVDENLYSF
MSDDLISIQSSCLSIAKTFANFNIQRKRFMISTETEMDTFHKKDDIDVWV
GGKSYNPARSFRNNPINELTVIDFEEMADILLLMLRDNLIRSFEINVCNT
LFELDKNGEPTTFNLDKIDSIINKWWSENVSTEIIPNLIKKLRENPLFNI
GFMVNDILERMYKEDIPKSYLTSVPLVISKKARSTLSIKSNGSQKIDKSK
FAQILSL
>M5005_Spy1213 phage protein
MWGKIEALLIEKKMTKYELSQKAGLNQNCLIDLKKGRKKSLKFDDVVKIA
DVLGVSLDEFR
>M5005_Spy0914 phage transcriptional repressor
MLHVNKMTISNWEKGKNIPNEKHLNALLHLFNVTSDYFDPNYRLLTPYNQ
LTISNKEKVIGYSERLLNHQIDKKSKDLIDKPSQLYAYRVYESLSAGTGY
SYFGDGNFDVVFYDEQLEYDFASWVFGDSMEPTYLNGEVVLIKQNSFDYD
GAIYAVEWDGQTYIKKVFREDEGLRLVSLNKKYSDKFAPYSEEPRIIGKI
IANFRPLEI
>M5005_Spy0483 stress-responsive transcriptional regulator
METKFYKQRKNRLVAGVIAGLADKYGWDLALARVLAALLIYGTGFGVLLY
ILLAIFLPYKEDLLEERYGRGPRRRKDADVLNEEEDGWFW
>M5005_Spy1830 transcriptional regulator, TetR family
MVNRKENTKQAILKAMVMLLKTESFDDITTVKLSKRAGISRSSFYTHYKD
KYEMIDYYQQTFFHKLEYIFEKKYQNKEQAFLEVFEFLQREQLLSSLLSA
NGTKEIQAFIINKVRLLITTDLQDKFSTEELSQTEKEYQSIYLAHAFFGV
CQSWIAKGKKESPQEMTQFVLKMLTST
>M5005_Spy1475 acetyltransferase
MVQQSLVIEEGVPQDAKAVLSLVTAAAKETDFITGVETILEATPQELSDF
LSRSQTSFIDFCLLARLDEKVVGLLNLSGEVLSQGQAEADVFMLVAKTYR
GYGIGQLLLEIALDWAEENPYIESLKLDVQVRNTKAIYLYKKYGFRIESM
RKNDIKSKNGDDLDVYHMRKSVSQ
>M5005_Spy1581 transcriptional regulator, MerR family
MSQFYSTGELANLAGVSIRTVQYYDQRGILIPTALTAGGRRLYTDSDLEQ
LRMICFLRDLGFSIEQIRKVLAEENAAQVLELLLVDHIATAKEDLAAKEQ
QVDIAVKILDRLRKQDPQSLDFLMDISLSMKNQKAWKKLQWKMGISIFLA
IVSYVGLILLSSYLQKFWLVYVAMGLFLPGFSWLVIYFRKQFIYLCPHCH
QKFEPSFNEFALAGHTPRTRKLTCSHCHQKSYCLELAKEDTVSRR
>M5005_Spy0991 transcriptional regulator, GntR family
MSWKFEEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIAGVNPNT
MQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNM
TKMGFSHTEIIPVLTSFLKEDSQ
>M5005_Spy0291 acetyltransferase, GNAT family
MLIRQVQGSDLEVIATIESDNFSPQEATTRAVLEEHIRLIPDTFLVALID
QEIVGYIEGPVVTTPILEDSLFHGVTKNPKTGGYIAITSLSIAKHFQQQG
VGTALLAALKDLVVAQQRTGLILTCHDYLISYYEMNGFINQGISESQHGG
TLWYQMIWKL
>M5005_Spy0451 transcriptional regulator
MRFSYNKLWKLLIDKGWTKTKLRQEAGISSSTIAKLGKGENITTDILLEI
CIALDCKIEDIVEIVDNNI
>M5005_Spy1083 transcription antiterminator, BglG family
MLSKKELAIITFLIHHKEQFVSSATLAEVIGMSDRTVRKYLKELISSLPE
HGAHIISKQGRGYCLEIDHSMAFDIFWQESVTSKKRLADVTQVEESVDRE
DYVLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEI
THQHIQIRGKEEDIRHFIMDYFFVTSFDNTLSTMVGNTFLEGINFAEIMI
IVLDECRDAKLKLSDFVMNNLVLHIALMVQRIRSGCPLELFSIPIAIRQS
DEYQVALRILYRVEEVMGIRFPKEEANYIALHLKVKHSVGKHWQDDNTDE
KLQDHLKACIAKISQLTGMTLETDTNLFQGLLAHMMPLTIRLENHIQLTN
PLTEEIKSQYPEIFTLTKQTFSDLLVCQKNDVSDDEWAYISLHLMAAIER
YSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEER
LKTVDLIISSISLANLMFLTPVITVSVFLSNQDIETIRQFIGEQEGIKKE
VSLPSQMSLAKAEQLLTGVFSPNRFLYLDEKISKEDLLLRMIACLDEAGT
ETFVEDFYHQMVLRENYSPVIYGEVLAFPHPANPMTYSEQVVVVICREPL
EWDKAHQAVHFVFLLSPSKGHNHRLKYVSPGLASFVNQVELQQALLEEPN
YSKFMTVFTPLIHD
>M5005_Spy0636 transcriptional regulator, LysR family
MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSIKDLEAELGFQIFNR
TTSGTVLTSQGLVFYEKALEVVKSFDSFEKTFSQADLDQNEFSIASQHYD
FLPPLITAFSQQYDGHRVFRIFESTTIQILDEVAQGNSEIGIIYLNVDNQ
KGLFQRMDKLGLEYVSLIPFTTHIYLSKTHPLANREALYLNDIQGLPAVR
FTQERDEYLYYSENFVDTSECPRIYNVSDRATLNGILERTNAFATGSGFL
DHRSVNGIKVIPLADHIDNQMIYVKRKDKNLSVAGATFVTILKDYFDKRR
KALT
>M5005_Spy1664 transcription antiterminator, BglG family
MLSHELIRNYQLFSKYKGHSLEAFESILKASKRHILADIAKINDTLSLYQ
LPLIALDRQLVYPPDLTEKDLLNRMLPTLDDYLFQDERLDMIIIYIMMAK
EFISINHLESLLRLSRNSVIADLNLVRDRVQAFQVTLAYNRQDGYFFEGE
PLALRRLLESAVSSLLQVTSGPWVFSYLLHELGLPDQKKVMAATLEELSR
ENHLTFISEKLRDLIYFFCLLAHRPFSRNVRAEAVDTFPLASPAVETMVD
QLLVNFPSLTEEKYLVQSRLLGCIQGDLELVFQQPIYDIMEEIINSVAVN
TGLSITDTPELRQNLYSHLLPAYYRLYYDINLTNPLKEQIKQDYESLFYL
VKRSLSPLEKQLGKSVNEDEVAYFTIHFGRWLQAPKKRPSNQLVALSVCP
NGISSSLMLEATLKELFPQLQFIRIHQLDKIKLLDPASFDLIFSTVAFDC
AKPVYVTQALMGPVEKMMLKKMVCDDFHLPLSEQFALDDLLSIIHKHTTI
TNKEGLVSDLSRYLIGNHLTIEKGGLGLLDLLTADFIRQADAVSDWQEAI
RLAAQPLLEHQMIETSYIDGMIDSVNELGAYIVLAPKVAVPHAAPEKGTR
QLGMSLLQLKEPVSFDLKQEGDPDKQVQLIFVLSAVDSSSHLKALQELSL
ILDDDEHIEQLIEAKNTEEIMSLISHMIEKGDESHD
>M5005_Spy0741 fibronectin-binding protein
MSFDGFFLHHLTNELKENLLYGRIQKVNQPFERELVLTIRNHRKNYKLLL
SAHPVFGRVQITQADFQNPQVPNTFTMIMRKYLQVQSLSS
>M5005_Spy1377 trans-acting positive regulator
MKIEDLMDKERRAQYRLLVTLYHAKETLRLKDLMRLSNLSKVTLLKYIDN
LNHLCREQGLACQLLLEKDSLSLKENGQFHWEDLVALLLKESVAYQILTY
MYCHEHFNITNLSVELMVSEATLNRQLAHLNQLLSEFDLALSQGRQLGSE
LQWRYFYFELFRHTLTRQGIDALVNQLDASHLATLIERLIGQSLSAEALE
QLLIWLAISQARMSFQKGYNDHFLRDSDFMTSNIFFKRLESMLLHYLRRY
ALEFDAFEAKSLFVFLHAYPLLPIASMKYSLGFGGPIADHISEALWLLKK
AHVIIHQTKEEIIYGLGIFFSKAYFFKGAILSQPTNSQYLYQLVGEDKRA
LLRVIINHLVLQMDQETDFSQQLSDDVLALLIFSIERHHEPLLVGLALGQ
NKVEAAIAELAIRRHLGHRRDFQLMPYDHQKVYDCLITYQTVCLPRQDLP
YYRLKQYSSPYELTALEAFLKDLFQQKNTREEELSLSPAAKSSFAHKTV
>M5005_Spy1024 phage protein
MARANKAKMLDAIEFKLLNPTANQAQVAEIIGITDRQLRNWENDPEDKSG
WNKLNDEIAEKAFGKYALSAIGTLVNLSKNAKSELVRLQASQDILDRAGY
KPTDKQEISIDEPIVLANSWVQDNGS
>M5005_Spy0866 phosphinothricin N-acetyltransferase
MLRPLSKTDCPMLQEINAKALGYLVSLDLLERQYERLIEDCHHYFLAYAD
KDTNQLLGYVHAERYETLYASDGLNLLGLAVLPAYQRRGIGSALLRALES
QARQEGIAFIRLNSASHRKEAHAFYRNLDYADDKTQLRFIKNLQGDDNDF
>M5005_Spy1747 sorbitol operon regulator
MKEERRRLLAKVAYLHYVQGKSQTLISKEMNIYRTTVCRMLAKAKEEGIV
RIEIADYDADLFALEEYVRQQYGLEKLDLVPNQVEDTPMDTLTNVAKTAA
EVFRHVVKDGDKIGLSWGATLSCLMDELNPKAMKDVFIYPLAGGPSHINA
KYHVNTLVYRLARIFHGNSAFMNAMVIQEDKHLAKGILQSKYFNDILTSW
DQLDLALVGIGGEPNSLEQSQWRDLLTSSDHDQLKYEKAVGEVCCRFFDQ
AGQPVYTGLQDRTIGISLEQLRRVPKTMAVATGKHKAKAILAALKAGFIN
YLVTDKETMLAVLALDEDIDLNNVLL
>M5005_Spy1050 phage transcriptional repressor
MKLGEIIKNFREEKKLSMDRFAEKSGLTKGYISMLEKNEHPKSKKPIIPT
EETLLKVAKGMGVDIDFVLSKLDSDQEIQINISPKNMLNMDNPSTPTTPK
VELIPSTLQKINSTSSQLEHSRQIIVLDTAETLLEQQKEIKNNEDTIAEL
FSYNYYDHAASAGTGQYLNDVQVEKIELPVDYDADFVIPVYGDSMEPKYH
SGDYVFVKLSVELTDGDIGVFEYYGDAYIKQLLINDEGAFLHSLNSKYED
IPIDRDSDFRIIGEVVGSYSGNHS
>M5005_Spy0968 transcriptional regulator, TetR family
MTKRHTETKAYVKTALTTLLTEQSFETLTVSDLTKKAGINRGTFYLHYTD
KFDMMNHFKNDTLDDLYRLLNQAEIYTDTRQVLNQTLSYLIEHREFITAL
ATISYLKFPQLIKDFCYQFLTTITGFQDIVTNQYHIPYPYALEVYLASIE
SIISYWIANGYQETTEEVADIILKAVTLDN
>M5005_Spy1447 phage-related DNA helicase
MRLHEYQEYAKTWIVEHPYCGLLLDMGLGKTLTTLSAIDEIQNIFSEDHK
ILIVAPKKVAEETWPTEIEKWHFDFTYSKVLGSEGKRIEALETEADIYLI
NRENVTWLVEYYKTKWPFTFVVIDELSSFKSSKSKRFRALRKVRPKVQRL
VGLTGTPAPNSLIDLWPQIYLMDRGDRLETSQTRFKDKYFVPDKRNGPII
YSWALRDGAEAEIYNKIEDICVSMKAKDYLKLPPRTNNVVSVKLSNMKAY
KQLEADLVLEFKDKEISAANSAVLANKLLQMANGAIYDDDKSTVAIHDDK
LDALEDIVEESQGQPILVFYQYQHDFERLKKRFPQAEELTSVDKWNSGKI
PILLCHPQSAGHGLNLQKGGHIIVWFGLTWSLEYYQQANARLDRQGQTEP
VIVHHIVAENTVDEKVLRILQGKEKNQNALLEAVKAQLGV
>M5005_Spy1578 transcriptional regulator, Cro/CI family
MTKSTLKELRTTKKMTQQELSHLTGISVRTIARYEKDTKKLRRAKYEKLK
GIAQALAVSVDDIFLGIDSEFMN
>M5005_Spy1218 phage protein
MPDNTIAIEKIKKYLLDNNLKQVDLAVTYGKEPQDVANILAGRKKDPASN
RFVLKVISDLKIR
>M5005_Spy0917 transcriptional regulator, GntR family
MLPAYIKIHDAIKKDIDLGIWPIGSRLPSERHLAEHFTVSRMTLRQAITL
LVEEGILERRIGSGTYVASHRVQEKMRGTTSFTEIIRSQGRQPSSKLLSY
QKQLASDTEVKELNLDKTDLVIRMERIRYADSVPLVYEIASIPEKFIKTV
KRADITEHFFHSLIANGYEIGKSKQTIYAKLASERVASYLEVAKGHAILA
LTQVSYFTDGKPFEYVRSQYIGDRFEFYLENN
>M5005_Spy1822 transcriptional regulator
MMLSKSLQVPLEQLIAEDIPKMTLIIKDEEIKQCDRNTHIMLFGTLLIAI
SIYPIMSWLGWWGYGPVAILWLIIMRIALRIERFKKTYDVQTYR
>M5005_Spy1392 transcriptional regulator, TetR family
MTDKALSKRSLQNLTQFNKETRRIARESMEIALLNLLETKPLGDITISEL
VTKAGVSRNAFYRNYTSKEAIIEQLLVGVIRRIFRGLKQFDIKTQAYQAW
LYLFTEAKKEAQLLKMIFKHHLHHLLTRLVTKRLKAYQKLKDKKQSHYKR
LFWSNAIVSVLTNWISDDMIVPAEEMAAMGLPLLT
>M5005_Spy0438 acpA, ribonuclease III
MKQLEELLSTSFDIQFNDLTLLETAFTHTSYANEHRLLNVSHNERLEFLG
DAVLQLIISEYLFAKYPKKTEGDMSKLRSMIVREESLAGFSRFCSFDAYI
KLGKGEEKSGGRRRDTILGDLFEAFLGALLLDKGIDAVRRFLKQVMIPQV
EKGNFERVKDYKTCLQEFLQTKGDVAIDYQVISEKGPAHAKQFEVSIVVN
GAVLSKGLGKSKKLAEQDAAKNALAQLSEV
>M5005_Spy0077 adcR, transcriptional regulator, MarR family
MGILEKKLDNLVNTILLKAENQHELLFGACQSDVKLTNTQEHILMLLSQQ
RLTNTDLAKALNISQAAVTKAIKSLVKQDMLAGTKDTVDARVTYFELTEL
AKPIASEHTHHHDETLNVYNRLLQKFSAKELEIVDKFVTVFAEELEG
>M5005_Spy1229 argR1, arginine repressor
MKKSERLELIKKMVLTHPIETQHDLLRLLAEHGLELTQATISRDMNEIGI
VKIPSGSGRYIYGLSQDSGKKIVQGPRSIKSTILAVSDKTKGLEQHLYLK
VVPGNSKLIKRYLLADFSKAIFSLIADDDSLLLIAKSPSEADMIRQEILL
WMQGIT
>M5005_Spy1807 argR2, arginine repressor
MNKMERQQQIKRIIQAEHIGTQEDIKNHLQKEGIVVTQATLSRDLREIGL
LKLRDEQGKLYYSLSEPVATPFSPEVRFYVLKVDRAGFMLVLHTNLGEAD
VLANLIDNDAIEDILGTIAGADTLLVICRDEEIAKRFEKDLAAGL
>M5005_Spy1110 birA, biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase
MKTSEKIYQLLSQTDDFVSGEYLADQLSISRTSVWKSIKSLENQGIQIDS
LKHKGYRMVQGDILLPKTISQGLGMPVTYTPHSQSTQLDAKQGIEAHNSA
PRLYLAPSQEAAKGRLDRQFFSASTGGIYMSMYLKPNVPYADMPPYTMMV
ASSIVKAISRLTGIDTEIKWVNDIYLGNHKVAGILTEAITSVETGLITDV
IIGVGLNFFVTDFPEAIAQKAGSLFTEKPTITRNDLIIDIWKLFLSIPVK
DHVKVYKEKSLVLNKQVTFIENSQEKRAIAIDLTDQGHLIVQFENGDLQT
LRSGEISLSSWEN
>M5005_Spy1818 cadC, cadmium efflux system accessory protein
MGCVRLGEKIMKKDSICQVGVINQQNVTTATNYLEKEKVQKSLRILSKFT
DNKQINIIFYLLAVEELCVCDIACLLNLSMASASHHLRKLANQNILDTRR
EGKIIYYFIKDEEIRDFFNQLG
>M5005_Spy0424 ccpA, catabolite control protein A
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDY
RPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLA
SSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAG
TVDLDHQLPSVNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRL
AGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSGATAAYVAEDE
LAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGA
VSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK
>M5005_Spy0948 ciaR, transcriptional regulatory protein
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGIYDLILL
DLMLPEKNGFQVLKELREKDIKIPVLIMTAKEGLDDKGHGFELGADDYLT
KPFYLEELKMRIQALLKRTGKFADKNISFGNLVVDLARKEVKVEGKVVEL
LGKEFDLLVYLLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKIRKK
LKGTCFVNRLQTLRSVGYILKNNE
>M5005_Spy0899 citG, transcriptional regulator, GntR family
MNPIIEAVKQNLDLSRNIPLKIAFYNALKKTIILRQIPVGSRINEKEFSI
ALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIKDACEIFEIRKAL
ETLATVQAMHLMTEEDFKVMHNLLEDCETFIAEDDTNRILDNFNAFNNLI
YSYSQMVRLKEIVTELQAYLVYFRKISISSVERRKRALSEHWMIYRGMKN
KDHEQITLITHEHLNSSLEFILKEMRPEQND
>M5005_Spy1512 codY, transcription pleiotropic repressor
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGG
TLLGYAMKYKTNTDRVEEFFEAKQFPDTYVKAASRVYDTEANLSVENELT
IFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEIS
STVVGIQLLNLQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDG
NEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLGMKGTYLKVIN
EGIFAKLKEF
>M5005_Spy1406 copY, copAB ATPases metal-fist type repressor
MQQISAAEWEVMRVVWASGDIKSSDIITILRKKYQWSDSTIKTLIGRLVK
KNFLTSYRQGRAYIYQALLDETLLQKEALATVLDGICQRQHTRLLLERLY
HLPMTLEEIGAFQELLEVKKENAVLEVPCNCLPGQCHCQRKETY
>M5005_Spy0282 covR, response regulator
MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALEKEFDLI
LLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYI
VKPFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGD
DEISLTKREYDLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIR
YLRGKIDIPGKESYIQTVRGMGYVIREK
>M5005_Spy0701 cpsY, transcriptional regulator, LysR family
MNEAAKQLFITQPSLSNAVKDLEMEMGITIFNRNPKGITLTKDGVEFLSY
ARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFVVNAFVSLLKRTDMTR
YELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDDNHLTASP
LFKAQPHIFVSKSNPLATKSLLSMDDLRDFPYLSYDQGIHNSFYFSEEMM
SQMPHNKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDV
PDEIDIVFIKHEKANLSKMGERFIEYLLEEVTFD
>M5005_Spy1589 crgR, transcriptional regulator, GntR family
MSTNDLTKKLKKLKHVQVYNTIFQLIQDGTYSPGMQLPSEPELARQLNVS
RMTLRKSLALLQEDHLIKNIRGKGNFILKTPETKYHQGFEYLQHPIYASL
SSDITKVELEYRIEVPTVAITASLKQETPVVIIVDRWYHSQNKAIAYSLS
FIPIEVISKYAINLNQEEPLLTFLEEKIYESGKASHSCNQIGYTKTGNYT
ATKYTLSENSAFILIQETLYNGKDILVSTKHYVPADLFDLKVQSQSC
>M5005_Spy1765 csp, cold shock protein
MYMAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQTNGFKTLEEGQKVA
FDVEEGQRGPQAVNITKLA
>M5005_Spy1764 ctsR, transcriptional regulator
MPTKNTSDSIEEYIKELLAKSGIAEIKRSMLADSFQVVPSQINYVIKTRF
TESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGNLMATIEDCISEQVFTD
SIQLLFDEHLLTEREGNIILAVASDDVLGTDGSTIRARMLYRLLQRIDRK
GSN
>M5005_Spy1154 deaD, ATP-dependent RNA helicase
MKFTEFNLSQDIQSAVVTAGFEKASPIQEMTIPLALEGKDVIGQAQTGTG
KTAAFGLPTLNKIRTNENIIQALVIAPTRELAVQSQEELFRFGREKGVKV
RSVYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALILDHVETLILD
EADEMLNMGFLEDIEAIISRVPADRQTLLFSATMPAPIKQIGVKFMKDPE
HVQIKNKELTNVNVDQYYVRVKEQEKFDTMTRLMDVNQPELSIVFGRTKR
RVDEITRGLKLRGFRAEGIHGDLDQNKRLRVIRDFKNDQIDILVATDVAA
RGLDISGVTHVYNYDITQDPESYVHRIGRTGRAGKSGESITFVSPNEMGY
LSMIENLTKKQMKPLRPATAEEAFQAKKKVALKKIERDFADETIRSNFDK
FKGDAVQLAAEFTPEELALYILSLTVQDPDSLPEVEIAREKPLPFKYVGG
GHGNKNGKGGRGRDNRNRGDRRGGYRGDRNRDERDGDRRRQKRDKRDGHD
GSGNRDFKRKSKRNSKDFFNKEKKSSAKNTGFVIRHKGE
>M5005_Spy1117 deaD2, ATP-dependent RNA helicase
MITKFPPQWQEKLDQVAFTHLTPIQEQAFQPIVDGKNFLGISPTGTGKTL
AYVFPSLLALTPKKSQQLLILAPNTELAGQIFEVTKDWAQPLGLTAQLFI
SGTSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMSVNTIVLDEYDE
LLGDSQYDFVQKISHYVPRDHQMVYMSATNKVDQTSLAPNTFCIDLSEQT
NDAIQHFYLMVDKRERTDLLRKFTNIPHFRALVFFNSLSDLGATEERLQY
NGAAAVSLASDINVKFRKTILEKFKSHQLSLLLATDLVARGIDIDNLDYV
IHFDVARDKENYTHRAGRTGRMGKSGIVITFVSHPEDLKKLKKFAKVSEI
SLKNQQLHFIN
>M5005_Spy0536 dinG, ATP-dependent helicase
MTQKKLRKYAVVDLEATGAGPNASIIQVGIVIIQGNKIIDSYETDVNPHE
SLDEHIVHLTGITDKQLAKAPDFGQVAHHIYQLIEDCIFVAHNVKFDANL
LAEALFLEGYELTIPRVDTVELAQLFFPRFEKYNLSHLSRQLNIDLAEAH
TAIADARATAILFLRLLQKIESLPIECLESLLVYSDSLLFETAMVIQEGL
AKAKPYDPNKYIKIRQILLPKGSKALKPYQISKSFPINMALLGLEERPKQ
TQFAQLIDEDYHQGVASFIEAQTGIGKTYGYLLPLLAKEDQNQIIVSVPT
KLLQDQLMAGEVAAIQEQFHIACHSLKGPANYLKLDSFADSLDQNDQNRL
VNRYKMQLLVWLLETKTGDLDEIKQKQRFAAYFEQLKHDGDIKQSSEFYD
YDFWRVSYEKAKTARLLITNHAYFLHRVQDDKDFARNKVLVFDEAQKLML
QLDQLSRHQLNLTVFLQTIQAKLSNPLPLLEKRLLESLSFELGQVSSDYY
QNKEHQLAHDWSRIAGYAKELTGADYQELQAFFATSDGDYWLSSEKQEEK
RVTYLNSASKAFIHFQQLLPETVKTYFVSATLTISSEVTLADLLGFEEYL
YHVIEKDKKQDQLVLVDQEAPIVTEVSDQIYVEAIAKRIESLKQEGYPIL
VLFNSKKHLLLVSDYLDQWQVPHLAQEKNGTAYNIKKRFDQGEQTILLGL
GSFWEGVDFIQADRMITLIARLPFDNPEDFFVKKMSHYLLEKGKNPFRDY
FLPMTILRLKQAIGRTMRRQDQKSVVIILDRRLLTKSYGQVILEGLGQEF
LISQQNFHDCLVETDCFLI
>M5005_Spy0830 dpiA, transcriptional regulatory protein
MNVLIIEDDPMVDFIHRNYLEKLNLFDRIISSDSMKAVQSILTDYAIDLI
LLDIHITDGNGIQFLEKWRTQHIPCEVIIISAANDGNIIRDGFHLGIIDY
LIKPFTFERFQESIQQFVTHREHLANQQLEQAQIDQLKCLTSKKDTKNKQ
LLEKGLSESTFQWIMENIKVFDQPFTIQELASACHLSHVSVRKYIAYLEE
NKQLNSQQIFTKVGRPYRVYW
>M5005_Spy0206 fasA, response regulator
MMNIFILEDDFIQQTRIESIVVGILKETRIPCNQLEVFSTPQKLFESIQE
RGDHQLYFLDIEIGEYTRCGLELAAAIRQKDPNAVIVFVTTHSEFAPISF
KYKVSALDFIDKAGGQKQFKEQIEECIRYTYDMMSSRESKDMFLFETPQT
RLKLPYKDILYFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCH
RSYLVNLDKVVRIDKSKQLLYFENGDSCMVSRLKMKCLFERWEALR
>M5005_Spy0740 fbp, fibronectin-binding protein
MGKHSNIILVDRAENKIIESIKHVGFSQNSYRTILPGSTYIEPPKTAAVN
PFTITDVPLFEILQTQELTVKSLQQHFQGLGRDTAKELAELLTTDKLKRF
REFFARPTQANLTTASFAPVLFSDSHATFETLSDMLDHFYQDKAERDRIN
QQASDLIHRVQTELDKNRNKLSKQEAELLATENAELFRQKGELLTTYLSL
VPNNQDSVILDNYYTGEKIEIALDKALTPNQNAQRYFKKYQKLKEAVKHL
SGLIADTKQSITYFESVDYNLSQASIDDIEDIREELYQAGFLKSRQRDKR
HKRKKPEQYLASDGTTILMVGRNNLQNEELTFKMAKKGELWFHAKDIPGS
HVIIKDNLDPSDEVKTDAAELAAYYSKARLSNLVQVDMIEAKKLHKPSGA
KPGFVTYTGQKTLRVTPDQAKILSMKLS
>M5005_Spy0660 fruR, fructose repressor
MAKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHGGAELFH
SLQEELSNQEKSVKNSHIKKAIAQRASQLIYDNDVIFIDAGTTTEFLLPF
LQAKNLTVVTNSIHHAARLVELSIETIIVGGYVKQTTDASIGNVALEQIR
QMNFDKAFLGMNGVDDSYLTTPDMEEAVIKKAVLSNAKLAYILVDGTKIG
QVSFVKVAPINDVTIITLGGSASILKQIKEKAKVIEL
>M5005_Spy1257 glcK, glucokinase/Xylose repressor
MSQKLLGIDLGGTTIKFGILTAAGEVQEKWAIETNILEGGKHIVPDIIAS
IKHRLDLYGLSSADFVGIGMGSPGAVDRDTNTVTGAFNLNWKETQEVGSV
VEKELGIPFAIDNDANVAALGERWVGAGENNPDVVFMTLGTGVGGGIIAD
GNLIHGVAGAGGEIGHMIVEPENGFACTCGSHGCLETVASATGVVKVARL
LAEAYEGDSAIKAAIDNGEGVTSKDIFMAAEAGDSFADSVVEKVGYYLGL
ASANISNILNPDSVVIGGGVSAAGEFLRSRIEKYFVTFTFPQVRYSTKIK
IAELGNDAGIIGAASLARQFITK
>M5005_Spy0293 greA, transcription elongation factor
MFVFLIRSKKKREKTIMAEKTYPMTLTEKEQLEKELEELKLVRRPEIVER
IKIARSYGDLSENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAK
DEVAIGKTVIVQEVGTTDKDTYHIVGAAGADIFSGKISNESPIAQALIGK
KTGDKVRIESPAATYDVEIISVEKTN
>M5005_Spy1500 hrcA, heat-inducible transcription repressor
MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDMAKLEKL
GLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKAFDFEAFK
LEDMLQKASHILAEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMT
LDESKPVTVQFAIPRNFLTRDLIAFKAIVEERLLDNSVIDIHYKLRTEIP
QIVQKYFVTTDNVLQLFDYVFSELFLETVFVAGKVNSLTYSDLSTYQFLD
NEQQVAISLRQSLKEGEMASVQVADSQEAALADVSVLTHKFLIPYRGFGL
LSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYRYLNSNHYEVH
>M5005_Spy1725 irr, two-component response regulator
MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTTSYDLII
LDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVT
KPFSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTK
KEYDIIDYLAKRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTG
IPLKTITGMGYLLGERE
>M5005_Spy1402 lacR.1, lactose phosphotransferase system repressor
MLKRERLLKITEIVNEQGIVTVNDIIQTLNVSDMTVRRDLDELEKAGKLI
RIHGGAQSITMPNKKERSNIEKQTVQTKEKWELASYATQLVNDGETIFIG
PGTTLECFAEQLKNRQIRIVTNSLPVFNILQDSETIDLILIGGEYRSITG
AFVGSLASQNISSLKFAKAFISCNGIYKNDIATYSETEGEIQKLAFNNSI
EKYLLVDNQKFNAYDFFIFYHLNNIDAVVTDSQITEDVIERYSQFTQLLV
AHENKE
>M5005_Spy1639 lacR.2, lactose phosphotransferase system repressor
MKKKERHEKILDILKVDGFIKVKDIIDEMNISDMTARRDLDTLADKGLLI
RTHGGAQYLDYSSAKDEGHEKTHTEKKVLQTTEKKQIAQRAKNIIKDGET
VFIGPGTTLEHLAVELKNRNIRVITNSLPVFLILHPSTTIDLILIGGECR
EITGAFVGAIAINNLETLTFSKAFVSANAVYNNSIATYSDLEGEVQRVAL
NNAVEKILLVDSTKFESYDFYNFYQLDQVDLIVTDKNVTTDIIEKYKKFS
KIIIADK
>M5005_Spy0474 licT, transcription antiterminator, BglG family
MLIKRVLNHNAAISTNHQGLDILLMGKGIAFGKKVGDSIELNAIETSFVL
KNSDNMNRFTELFITVPQEVVACSERIINLGKIKLGKTLDEILYINLTDH
IHSAIERHEQGMLIHNPLRWEIQRYYPDEYSLGVKALELIERNLGVTLAI
DEAAFIAMHFVNASLDTPFKEPHRLTEIVSYIEQKIKTDFKTELDDTSID
YYRFMTHIKLFAQRVLSQMSYDDDDAELLLVVKTKYPKEYRCVLDISEEI
KKRYNYHLNSSELLYLTVHVKRLVKHLKET
>M5005_Spy1474 lytR, transcriptional regulator, LytR family
MKIGKKIVLMFTAIVLTTVLALGVYLTSAYTFSTGELSKTFKDFSTSSNK
SDAIKQTRAFSILLMGVDTGSSERASKWEGNSDSMILVTVNPKTKKTTMT
SLERDTLTTLSGPKNNEMNGVEAKLNAAYAAGGAQMAIMTVQDLLNITID
NYVQINMQGLIDLVNAVGGITVTNEFDFPISIAENEPEYQATVAPGTHKI
NGEQALVYARMRYDDPEGDYGRQKRQREVIQKVLKKILALDSISSYRKIL
SAVSSNMQTNIEISSRTIPSLLGYRDALRTIKTYQLKGEDATLSDGGSYQ
IVTSNHLLEIQNRIRTELGLHKVNQLKTNATVYENLYGSTKSQTVNNNYD
SSGQAPSYSDSHSSYANYSSGVDTGQSASTDQDSTASSHRPATPSSSSDA
LAADESSSSGSGSLVPPANINPQT
>M5005_Spy1057 malR, transcriptional regulator, LacI family
MVTIKDVAQKAGVNPSTVSRVLKDNRSISMKTKEKVRKAMADLGYVPNVA
AQILASGLTHNIGLVFPPITTSDRLSEPFFMEILSTITNEAKESHFTVSI
ATGISLDDLIEQVKLMHLQKRVDGFIILYSDQDDPVKKYLMTNNLPFVIV
GAPQGDTNKTTYIDNDNQLMAKTAVEHLYQKGHHNILFITDDLLSEVTSE
RYLGYLKGCFKRSLKTKPMLLFDRKDPVSVEILMETISSFKATALVVVGD
VLAIRMVQLLSFYDIKVPDDMSIITFNNSNYAKLIHPYLTTFDINVENLG
KMSFKQLLDIINSNEQNLSQTIFVPFSLKQRESVRDISH
>M5005_Spy1720 mga, trans-acting positive regulator
MYVSKLFTSQQWRELKLISYVTENADAIGVKDKELSKALNISMLTLQTCL
TNMQFMKEVGGITYKNGYITIWYHQHCGLQEVYQKALRHSQSFKLLETLF
FRDFNSLEELAEELFVSLSTLKRLIKKTNAYLMHTFGITILTSPVQVSGD
EHQIRLFYLKYFSEAYKISEWPFGEILNLKNCERLLSLMIKEVDVRVNFT
LFQHLKILSSVNLIRYYKGHSAVYDNKKTSQRFSQLIQSSLEFQDLSRLF
HLKFGLYLDETTIAEMFSNHVNDQLEIGYAFDSIKQDSPTGCRKVTNWVH
LLDELEIRLNLSVTNKYEVAVILHNTTVLKEEDITANYLFFDYKKSYLNF
YKQEHPHLYKAFVAGVEKLMRSEKEPISTELTNQLIYAFFITWENSFLKV
NQKDEKIRLLVIERSFNSVGNFLKKYVGEFFSITNFNELDALTIDLEEIE
KQYDVIVTDVMVGKSEELEIFFFHKMIPEAIIDKLNAFLNISFADSLPLD
KPINPLDFHRKEVILPTPPNKLHAPPSTT
>M5005_Spy0407 mutR, transcriptional regulator
MEKELGKTLRRLRKGKQVSISFLADEYLSKSQISRFERGESEITCSRLLN
LLDKLNITIDEFVSAHSKTHTHFFTLLSQARKCYAEKNVVKLTKLLKDYA
HKDYERTMIKAILFSIDSSIAPSQEELTRLTDYLFKVEQWGYYEIILLGN
CSRFMNYNTLFLLTKEMVASFAYSEQNKTNKMLVTQLSINCLIISIDHSC
FEHSRYLINKIDLLLRDELNFYEKTVFLYVHGYYKLKQEEMSGEEDMRQA
LQIFKYLGEDSLYYSYKEHYRQIVLGGKGDEDWSEADL
>M5005_Spy1412 nusA, N utilization substance protein A
MSKEMLEAFRILEEEKHIDKADIIDAVTESLKSAYKRRYGQSESCVIEFN
EKTADFQVFTVREVVEEVFDSRLEISLKDALAISSAYELGDKIRFEESVN
EFGRVAAQSAKQTIMEKMRRQMREVMFNEYKEHEGEIMTGTVERFDQRFI
YVNLGSLEAQLSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSH
PEFIKRIMEQEIPEVFDGTVEIMSVSREAGDRTKVAVRSHNPNVDAIGTI
VGRGGSNIKKVISKFHPKRVDAKTGLEIPVEENIDVIQWVDDPAEFIYNA
IAPAEVDMVLFDDEDLKRATVVVPDSKLSLAIGRRGQNVRLAAHLTGYRI
DIKSASEYDRLEAEKEAATAVEEPVVDDVMTAEEV
>M5005_Spy1545 nusB, N utilization substance protein B
MTNSFQNSRRDLRERAFQALFNIEMGAELLAASQFAYGYDKVTGEDAQVL
ELPIFLLSLVTGVNNHKEELDNLISTHLKKGWSLERLTLTDKTLLRLGLF
EIKYFDETPDRVALNEIIEVAKKYSDETSAKFINGLLSQYVSGAPSANKS
>M5005_Spy0138 nusG, transcription antitermination protein
MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIPTQTVN
VEKNGQTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRS
KPTPLLEEEIRAILLSMGQTIDVFDTNIKEGDVVQIIDGAFMGQEGRVVE
IENNKVKLMLNMFGSETVAEVELYQIAEL
>M5005_Spy1866 parB, chromosome partitioning protein
MFLILSRNSLMTKELLIDLPIEDIVTNPYQPRIQFNQRELQDLATSIKSN
GLIQPIIVRKSDIFGYELVAGERRLKASKMAGLKKVPAIIKKISTLESMQ
QAIVENLQRSNLNAIEEAKAYQLLVEKKHMTHDEIAKYMGKSRPYISNTL
RLLQLPAPIIKAIEEGKISAGHARALLTLSDDKQQLYLTHKIQNEGLSVR
QIEQLVTSTPSSKLSKKTKNIFATSLEKQLAKSLGLSVNMKLTANHSGYL
QISFSNDDELNRIINKLK
>M5005_Spy1519 recG, ATP-dependent DNA helicase
MILTAPMSNLKGFGPKSAEKFQKLDIYTVEDLLLYYPFRYEDFKSKSVFD
LVDGEKAVITGLVVTPANVQYYGFKRNRLSFKLRQGEAVLNVSFFNQPYL
ADKIELGQEVAVFGKWDATKSAITGMKVLAQVEDDMQPVYRVAQGISQST
LIKAIKSAFEIDAHLELKENLPATLLEKYRLMGRSQACLAMHFPKDITEY
KQALRRIKFEELFYFQMNLQVLKAENKSETNGLPILYSKRAMETKISSLP
FILTNAQKRSLDDILSDMSSGAHMNRLLQGDVGSGKTVIAGLSMYAAYTA
GFQSALMVPTEILAEQHYISLQELFPDLSIAILTSGMKAAVKRTVLAAIA
NGSVDMIVGTHALIQDSVQYHKLGLVITDEQHRFGVKQRRIFREKGENPD
VLMMTATPIPRTLAITAFGEMDVSIIDELPAGRKPIMTRWVKHEQLGTVL
EWVKGELQKDAQVYVISPLIEESEALDLKNAVALHAELSTYFEGIAKVAL
VHGRMKNDEKDAIMQDFKDKKSHILVSTTVIEVGVNVPNATIMIIMDADR
FGLSQLHQLRGRVGRGYKQSYAVLVANPKTDSGKKRMTIMTETTDGFVLA
ESDLKMRGSGEIFGTRQSGIPEFQVADIVEDYPILEEARKVSAAIVSDPN
WIYEKQWQLVAQNIRKKEVYD
>M5005_Spy0517 regR, transcriptional regulator, LacI family
MQRKVTIKDIAELAKTSKTTVSFYLNGRFDKMSEETKNRISESIKATNYK
PSIAARSLNAKSTKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGN
SNYDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIDIKKKKVVFFDS
QLYEHRTNWVKTNNYDAVYDTIQQCIDKGYEHFIMITGNPNLLSTRIERA
SGFIDVLEANHLTHQEMIIDENQTSSEAIAQFLQGSLTKKSLVFVPNCWA
LPKVFTAMKSLKFNIPEIGLVGFDNIEWTKFSSPTLTTIIQPAYEEGEQA
TKILIDDIEGHSQEAKQQIFDCQVNWQESTF
>M5005_Spy1686 relA, GTPpyrophosphokinase/guanosine-3',5'-bis(diphosp hate)3'-pyrophosphohydrolase
MAKIMNVTGEEVIALAATYMTKADVAFVAKALAYATAAHFYQVRKSGEPY
IVHPIQVAGILADLHLDAVTVACGFLHDVVEDTDITLDEIEADFGHDARD
IVDGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMR
TLKHLRKDKQERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNETEF
YKISHMMKEKRREREALVEAIVSKVKTYTTQQGLFGDVYGRPKHIYSIYR
KMRDKKKRFDQIFDLIAIRCVMETQSDVYAMVGYIHELWRPMPGRFKDYI
AAPKANGYQSIHTTVYGPKGPIEIQIRTKDMHQVAEYGVAAHWAYKKGVR
GKVNQAEQAVGMNWIKELVELQDASNGDAVDFVDSVKEDIFSERIYVFTP
TGAVQELPKESGPIDFAYAIHTQIGEKATGAKVNGRMVPLTAKLKTGDVV
EIITNANSFGPSRDWVKLVKTNKARNKIRQFFKNQDKELSVNKGRDLLVS
YFQEQGYVANKYLDKKRIEAILPKVSVKSEESLYAAVGFGDISPISVFNK
LTEKERREEERAKAKAEAEELVKGGEVKHENKDVLKVRSENGVIIQGASG
LLMRIAKCCNPVPGDPIDGYITKGRGIAIHRSDCHNIKSQDGYQERLIEV
EWDLDNSSKDYQAEIDIYGLNRSGLLNDVLQILSNSTKSISTVNAQPTKD
MKFANIHVSFGIPNLTHLTTVVEKIKAVPDVYSVKRTNG
>M5005_Spy1737 rgg, transcriptional regulator
MEIGETVEFIRHSKNISIKQVCGDYLTRQTYYRFIKNNLDISSKKLLYIL
DNLNVNVDEFLFISNNFKQYKEFIDMDTAKHYFECRNIEGLNHILDSYKD
SKSTKEKNLFALVKVLLATLTEEDCLTERTYLSNYLINIETWSHYETVLF
NNCMFIFESCFIEMVFSKVILNLDKYNTLRYYGNESIRMFVNMLILFIQR
QEYDKASEILAKIEDYQLNDDCLYERCCVSFFDGIIGLINGKEGAEQKCV
QILEIFQLLNCKTIHHMFQTYLKAIKHKLS
>M5005_Spy0070 rpoA, DNA-directed RNA polymerase alpha chain
MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLSSLPGAA
VTSIKIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELEVE
GPAEVTAGDILTDSDIELVNPDHYLFTIAEGHSLRATMTVAKKRGYVPAE
GNKKDDAPVGTLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNG
TIIPEDALGLSARVLIEHLNLFTDLTEVAKATEVMKETEKVNDEKVLDRT
IEELDLSVRSYNCLKRAGINTVFDLTEKSEPEMMKVRNLGRKSLEEVKVK
LADLGLGLKNDK
>M5005_Spy0083 rpoB, DNA-directed RNA polymerase beta chain
MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSGLKEVFE
DVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVN
KETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKV
DKNGKVGYGSTVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALG
FSGDDEIVDIFGESDLVRNTIEKDIHKNPSDSRTDEALKEIYERLRPGEP
KTADSSRSLLIARFFDARRYDLAAVGRYKVNKKLNIKTRLLNQIIAENLV
DAETGEILVEAGTEMTRSVIESIEEHLDGDLNKFVYTPNDYAVVTEPVVL
QKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYFLNLAEGLG
KVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTR
DRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTP
YRKVDRATGTVTNEIVWLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRH
QGNNQEFSASVVDFVDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQ
AVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQQNGKVVFSDAEKVEIRRQD
GSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIADGPSMENGEMA
LGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDTKL
GPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDL
SAEERLLHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSG
VNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVD
IMLNPLGVPSRMNIGQVMELHLGMAARNLGIHIATPVFDGASSEDLWDTV
REAGMDSDAKTVLYDGRTGEPFDNRVSVGVMYMIKLHHMVDDKLHARSVG
PYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDVT
GRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDNEVEL
RDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK
>M5005_Spy0084 rpoC, DNA-directed RNA polymerase beta' chain
MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEV
IFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAP
VSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLL
TEREYREKLQEYGHGSFVAKMGAEAIQDLLKRVDLAAEIAELKEELKSAS
GQKRIKAVRRLDVLDAFNKSGNKPEWMVLNILPVIPPDLRPMVQLDGGRF
AASDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNG
RRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPT
LKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVERGDERIWD
ILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGN
YYLTMEDAGREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPW
KDNQRHKIMVTTVGKILFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPG
QDIQEVIDRLDINVPFKKKNLGNIIAETFKRFRTTETSAFLDRLKDLGYY
HSTLAGLTVGIADIPVIDNKAEIIDAAHHRVEEINKAFRRGLMTDDDRYV
AVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNISNFSQLAGMRG
LMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGY
LTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTR
KSVKHPETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVC
RHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTD
ITQGLPRIQEIFEARNPKGEAVITEVKGNVVEIEEDASTRTKKVYVQGKT
GMGEYVIPFTARMKVEVGDEVNRGAALTEGSIQPKRLLEVRDTLSVETYL
LAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGDTDLLPGTLMDIS
DFTDANKDIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETTRVLT
DAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAMNEIEVIDHT
EVSAEAVFTAEAE
>M5005_Spy0600 rpoD, RNA polymerase sigma factor
MTKQKEITTFNVQVAEFIRHHKKEGTAIDDDVTEKLVIPFALDADQIDDL
LERLTDGGISITDKEGNPSSKYIVEEPKPEELTDEELIGSNSAKVNDPVR
MYLKEIGVVPLLTSEEEKELAVAVAKGDLMAKQRLAEANLRLVVSIAKRY
VGRGMQFLDLIQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIA
DQARTIRIPVHMVETINKLVREQRNLLQELGQDPTPEQIAERMEMTPDKV
REILKIAQEPVSLETPIGEEDDSHLGDFIEDEVIENPVDYTTRVVLREQL
DEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGKVFNVTRERIRQIEAKA
LRKLRHPSRSKQLRDFIED
>M5005_Spy1611 rpoE, DNA-directed RNA polymerase delta chain
MVENDKIRRTALKLDVFAGQEKSELSMIEVARAILEERGRDNEMYFSDLV
NEIQNYLGKSDAGIRHALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEI
DEEIITLEEDEDGAQKRKKKRVNAFMDGDEDAIDYRDDDPEDEDFTEESA
EVEYDEEDPDDEKSEVESYDSELNEIIPEDDFEEVDINEEDEEDEEDEEP
VL
>M5005_Spy1625 salR, transcriptional regulatory protein
MKILLIDDHRLFAKSIQLLFQQYDEVDVIDTITSHFNDVTIDLSKYDIIL
LDINLANISKENGLEIAKELIQSTPHLKVVMLTGYVKSIYRERAKKVGAY
GFVDKNIDPKQLISILKKVDSGKKYFEQIESQDYVESLTDQEIAILNLSK
KGFSIKEIEETLQISRRTVFNHLTHIYSKLLVNNKQEAIYKAEQLGYFMD
F
>M5005_Spy0367 scaR, iron-dependent repressor
MTPNKEDYLKCIYEIGEQEPKITNKMVAEKMHVSAPAVSEMIKKMISQGW
IVKDKAKGYLLKDKGYALVANLYRKHRLIEVFLIHQLGYNTQEVHQEAEV
LEHTVSDSFIDRLDKILDFPDFCPHGGTIPRYGQPLVEMNTTTLNTITEL
GRFRLSRIHDHFDLIQYLEAHHLNINTELTLTQIDTFAKTYTICYGDKEL
VIPENIAKQLYVTAL
>M5005_Spy1539 scrK, fructokinase
MRHGCLDKSLCHHKDKKEQEKGENMGKLYGSIEAGGTKFVCAVGDEEFTV
VDKTQFPTTTPEETIARTIAYFKAFEADLAGMAIGSFGPIDIDPSSETYG
YITTTPKSGWANVDLLGQLSAAFKIPFDVTTDVNSSAYGEVLARPGVESL
VYYTIGTGIGAGAIQHGHFIGGLGHTEAGHTYVMPHPDDMAKGFLGVCPF
HKGCLEGMAAGPSIEARTGVRGERLDQEADVWDIQAFYIAQAALQATMLY
RPQVIVFGGGVMAQEHMVLRVHDKFTALLSGYLPVPDLTDYIVTPAVADN
GSATLGNFALAKLAAQGK
>M5005_Spy1544 scrR, sucrose operon repressor
MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTVNKVNKAMRELGYKPNN
LARSLQGKSTQLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEH
NPVKEREYLEMLAANQVDGIISSSHNLGIEDYERVEAPIVAFDRNLAPNI
PVISSDNFEGGKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQL
KRSAEIIKLPNNLSPVRREMEIKSILATRKPDGLFVSDDLTAILIMKVAK
QLHITIPEDMKVIGYDGTTFIQQYVPQLATIRQPIDEIAKLSVEILIKKI
KKEKTSKDYILPITLLPGASI
>M5005_Spy0288 snf, SWF/SNF family helicase
MMARLIPGRVRNEGIKLYEQGLVSFQDDNKGILQIEVETYQVQYGADDED
ITCQCDTFHMKHYCKHIAAVEYFLKNDQKGKLFLKQLTNQTKIKETTKKM
TSFGSLFLDSLAMNEDDSVKYRLSALGSRSPFSSDYWWSLKINRLPDDRS
YVIRDIKGFLQLIKKEGFYQIGKNYFEQLSWLQFDPSSQALIEFLWRLAS
DTDKGDNENIFPNHARHLRLPSGFFEEGIHYLTSLYDFTFEGPSQTYHHL
FVRSLEAEAGLYEFKVEVHRKSIELQIAEKNVQYLFDNDYLLYQDTFYHL
TLKQRKMVQAIRSLPIEADLAKHIHFDLDDHAKLAASLSDFKQIGLVEAP
KSFAIRDFEVTFQFDLLNRDEISCQLMFDYGNYQVSDKASLEALPFASHL
KKEEKINRSLLAFGFSPQFYSKKRLTSAKELYTFFEETVPCFERLGNVAL
STAIQALQVKEMPKIAIRRNQGLLDISFDFSTIIENDIDQAVTALFQNNP
YFVSQTGQLVVFDDETQKVSKSLQELRARQLKNGHLQLDGIRALQVSKLF
EGMTSVHFSKELEELAYHLQHPETFSIKPLPVKAQMRDYQRNGVQWLSML
NHYGFGGILADDMGLGKTLQTLAFLASHLKSDSKVLILSPSSLIYNWFDE
CQKFTPQLDVVVSYGLKQIRDQIIEEGHQITITSYSSFRQDFETYQAFHY
DYLILDEAQVIKNAQTKISHCLRAFNTANCFALSGTPIENKMLEIWSIFQ
IVLPGLLPTKKEFLKLTAEQVSRYIKPFVMRRKKEDVLPELPDLIETNYS
NEMTDEQKAIYLAQLRQMQDQIRNSSDVDISRQKIEILSGITRLRQICDT
PSLFMDYQGKSGKLDSLRILLTQIKENGHRALIFSQFRGMLDLAKQEMTA
LGLTSYQMTGSTPANERQEMTRAFNNGSKDAFLISLKAGGVGINLTGADT
VILIDLWWNPAVEMQAISRAYRIGQKENVEVYRLITRGTIEEKILELQES
KRNLVTTVLDGNESRASMSIEEIKEILGLNTH
>M5005_Spy0804 srtR, nisin biosynthesis two-component response regulator
MYKILAIDDDKEILKLMKTALEIENYHVITCQEIELPIVFDDFKGYDLIL
LDIMMPNISGTEFCYKIREEVHSPIIFVSALDGDNEIVQALNIGGDDFIV
KPFSLKQFVAKVNSHLKREERAKIKNEAEERVKRSFPPIEIYLEERMLYI
DKQPLFLTYREYEILELLSRHPYKVFTKEEIYEQVYSDEASALFHSISEY
IYQIRMKFSSFGINPIKTIRGIGYKWDV
>M5005_Spy0006 trcF, transcription-repair coupling factor
MDILELFSQNKKVQSWHSGLTTLGRQLVMGLSGSSKTLAIASAYLDDQKK
IVVVTSTQNEVEKLASDLSSLLDEELVFQFFADDVAAAEFIFASMDKALS
RIETLQFLRNPKSQGVLIVSLSGLRILLPNPDVFTKSQIQLTVGEDYDSD
TLTKQLMTIGYQKVSQVISPGEFSRRGDILDIYEITQELPYRLEFFGDDI
DSIRQFHPETQKSFEQLEGIFINPASDLIFEVSDFQRGIEQLEKALQTAQ
DDKKSYLEDVLAVSKNGFKHKDIRKFQSLFYEKEWSLLDYIPKGTPIFFD
DFQKLVDKNARFDLEIANLLTEDLQQGKALSNLNYFTDNYRELRHYKPAT
FFSNFHKGLGNIKFDQMHQLTQYAMQEFFNQFPLLIDEIKRYQKNQTTVI
VQVESQYAYERLEKSFQDYQFRLPLVSANQIVSRESQIVIGAISSGFYFA
DEKLALITEHEIYHKKIKRRARRSNISNAERLKDYNELAVGDYVVHNVHG
IGRFLGIETIQIQGIHRDYVTIQYQNSDRISLPIDQISSLSKYVSADGKE
PKINKLNDGRFQKTKQKVARQVEDIADDLLKLYAERSQQKGFSFSPDDDL
QRAFDDDFAFVETEDQLRSIKEIKADMESMQPMDRLLVGDVGFGKTEVAM
RAAFKAVNDHKQVAVLVPTTVLAQQHYENFKARFENYPVEVDVLSRFRSK
KEQAETLERVRKGQIDIIIGTHRLLSKDVVFSDLGLIVIDEEQRFGVKHK
ETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQTY
VLENNPGLVREAIIREMDRGGQIFYVYNKVDTIEKKVAELQELVPEASIG
FVHGQMSEIQLENTLIDFINGDYDVLVATTIIETGVDISNVNTLFIENAD
HMGLSTLYQLRGRVGRSNRIAYAYLMYRPDKVLTEVSEKRLEAIKGFTEL
GSGFKIAMRDLSIRGAGNILGASQSGFIDSVGFEMYSQLLEQAIASKQGK
TTVRQKGNTEINLQIDAYLPDDYIADERQKIDIYKRIREIQSREDYLNLQ
DELMDRFGEYPDQVAYLLEIALLKHYMDNAFAELVERKNNQVIVRFEVTS
LTYFLTQDYFEALSKTHLKAKISEHQGKIDIVFDVRHQKDYRILEELMLF
GERLSEIKIRKNNSVFK
>M5005_Spy0435 vicR, two-component response regulator
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLII
LDLMLPELDGLEVAKEIRKTSHVPIIMLSAKDSEFDKVIGLEIGADDYVT
KPFSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAF
VAKKHGQEVELTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRT
VDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD
>M5005_Spy1332 yvqC, two-component response regulator
MSKIKVILVDDHEMVRMGLKSFLNLQADIDVVGEASNGREGVDLALALKP
DVLVMDLVMPELGGVEATLEVLKKWKEAKVLVLTSYLDNEKIYPVIDAGA
KGYMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTA
REYDILHLLAKGYDNQTIADELFISLKTVKTHVSNILAKLEVGDRTQAVV
YAFRHHLVPQDDN