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# Prochlorococcus marinus subsp. marinus str. CCMP1375, CCMP1375; SS120

>Pro1148 5-formyltetrahydrofolate cyclo-ligase
MEKSNDKNALRIKFKNIRKATIYKQQKLIFEQAKKLIKSFTENQVKESLI
GIYWPLEDEVDLRSLRRLKGISIALPACMKKGEITYHRWTENPLSKDEYG
IPAPLSQPPLSPSKLKLLLVPALAVDNNGIRLGYGEGCFDRLRLKAIWQK
IPAFVVLPKACIAQSLLPKDEWDIPFNGWINEKESFHI
>Pro0558 Possible pterin-4 alpha-carbinolamine dehydratase-like protein
MHKWQERSRPLRLERRFEFATYELTRDFLDCLGKLCEKRQRFPDISFGKT
YVNLTLQIDSEDEDSQASDLDKEFAMEIDALIDEDSD
>Pro0092 4'-phosphopantetheinyl transferase related protein
MRLTDIQKPRVLPLWIFPMDSPLKEISISEEKIANSLHPRRAKEYKHARS
YVRFALSQFFKLNPLEIPLKASIGKAPLLGNNLGHVSFSHCNDALLIGWS
PTKLGVDIERSDRALSAEGISERFFHKYDQNNLKSLNNEDFRKKVLEQWV
IKEAAIKWQRGTLSKDLKNWHIKNKSNVAIHQTLNHEVKIQTTIYRSWII
AIASNDNQGKGDLMICAN
>Pro1857 4-amino-4-deoxychorismate lyase related type IV aminotransferase
MNNILDNQISWINGHWIKHNEPQLPINDRGLTLSDGIFETILIMNNQPIL
LNAHLDRWNESAILLGMAKPPTKDHILSLIKEAINKNPLAQGSAVLRLNW
SRGDNNGRGIKLSSANAKSSSHRFWLTLRAYKPSFKPITTMISKLEQRNA
NSKINQCKTFAYTQSIQARREANIAGFDDALLLSTNGEIACGTTSNLIVK
RRDKWLTPHISSGCLPGIMRQQGLNSGILKEAKISPEPEPKDQWLLINSL
SCHSIIKVNTKSFEEYEASKILWTSLTKS
>Pro0490 Pterin-4a-carbinolamine dehydratase
MENKLLSSQEIQELRKSLPTWEEAEGKLVKRFKFTNFIEAFGFMTKIAII
SESLSHHPEWTNIYSEVIIRLSTHDMGGITMLDYKLAKAIDAIKYE
>Pro1624 SAM dependent methyltransferase
MSTNWQKLVIQNFDEASSKYNNSANLQKIFAAKLAAQCSKKVINSGVWVD
LGSGTGLLANALEKINPNQSVIRVDGSPRMLAEHLPNKSTQLFNLNYGLP
KWENPPTLIASSFALHWLKDPEERLMEWFSALAPGGLLAIALPDEASFPE
WHEAAKKAKVACTAMKFPSHNALTNLVKADNIIFQQLESFTQKAPRVTSL
LKPLVNIGAQTSHHPALNISQWRRLQQSWPMVESNRTYNLTWLIHILLVK
K
>Pro0583 6-pyruvoyl-tetrahydropterin synthase
MSNQITGFSCSKHFEGYPCCHRQWKHPGHCSFVHGYSRSFTFYFRAKELD
AYGFVVDFSSMEALEKKLRGYFDHTFLVNMDDPLIPQWKKLHSEKALDLR
IMANVGMESTAKLVWEWANSILLERDLGRTCCSRAKASENNFNSAYFESI
PDWFTTLEVDS
>Pro0127 6-pyruvoyl-tetrahydropterin synthase
MNGVTSMNTHGKGRHCVITRRALFSASHQYSLPELSANDNSKQFGKCAIP
PGHGHNYELIVSMAGSLNVDGMVLNLSEVKHAIKQQVTSQLDFRCLNQTW
PEFDMSKPEGCLPTTEALTRIIWNRLKCYLPLVSLRLYEQPSLWADYLGK
NMEAFLTIKKHFSAAHRLAREELSQKENEMIYGKCARTNGHGHNYFVEIT
VKGTIDKRTGMLCDLASLEQLVEDLVIEPFDHTFLNKDITHFSNCVPTAE
NIALHIADILNNPIHSIGASLHKIRLQESPNNAAEIYTDITSLNDLKANT
YK
>Pro1046 Phosphosulfolactate phosphohydrolase related enzyme
MELSYFHVAKDVPSGIKPETSVVIDVLRATTTIACALNNGAEAVQTFADL
DNLKEQASCWPLSKRLLLGERGGKKIDGFDLGNSPLAVTSNVVKGKRLFM
STTNGTRSLERVKESKSLYTMSFINRKAVAEKLISNQSKSVLILGSGWEG
AYSLEDSLAAGALASFLLNKNPNSVHILNDELSAAVALWSCWENNIEGCL
RNATHGKRLERLGNHDDDFTCCSELDKICVVPTQREKGVLCSL
>Pro1786 SAM1, S-adenosylhomocysteine hydrolase
MVTAAASTSQVVGDSDFVVADITLADFGRKELAIAEKEMPGLMSLRDKYG
QEKPLQGARIAGSLHMTIQTGVLIETLVALGAQVRWASCNIFSTQDHAAA
AIAKAGVPVFAKKGETLSEYWSFTHSILEWSGEQGPNMILDDGGDATGLV
ILGSKAEKDISVLDNPSNEEEIALYASIKSKLSTDKSFYSRIKKIILGVT
EETTTGVARLYQMQKNGELPFPAINVNDSVTKSKFDNLYGCRESLVDGIK
RATDVMVAGKVALVIGYGDVGKGSAQSLRGLGATVMIAEIDPICALQAAM
EGYRVVRLDDVVEEIDIFVTATGNFQVICHDHLIRMKDEAIVSNIGHFDN
EIDVASLKSYQWENIKPQVDHITLPSGNKIILLAEGRLVNLGCATGHPSF
VMSNSFTNQVLAQIELFKKGDSYQNNVYVLPKHLDEMVARLHLDKIGANL
TELSKEQADYINVPIEGPYKSEQYRY
>Pro1390 cbiB, Cobalamin biosynthesis protein CobD/CbiB
MIGDPKFIPHPVEIMGCLIKFLREKVESSVHKGRLFFRFGGTLITFSVIS
LSALCGWIIEQLLFTSFFPIPQALSYLIVIFALASSLAAKSLKRSVLEII
NSLNNDLFKDNLELAQEKLSHIVGRDVDKLDRNEILRATAESASENAVDG
IFAPLFWMLIGIISWNISTTFPGPLAFAWFFKATSTIDSMLGYKVGNLRW
IGESGARLDDILTFLPCRLVLISLPLISNNWMKLFYIIRKAWSEGSKDIS
PNSGISEAIFAHCAQVQMGGINTYNKHSIEKPILAKNAPIANIQNIKKIL
NLSLRLEILWIIILISLHLLLS
>Pro0037 cbiD, Cobalamin biosynthesis protein CbiD
MRGFTLPVWVVAAAKAAVKVLIGESWQSHEVIELLNNEESIVVPIRSASI
LDNGEKALGITNCDPGECLDLTRGLEIWVCLRYIENQQIISSDGLELEPW
LKIIPGYGVGKFDLTNDISISEFARQLLIVNLKPYRKEGYSLNLEIIFPS
GQELAEKTSNHAFGVVDGLALIGTQADVQESASPKKLQSTIHALRSRCAE
SSFTGSLIFVIGENGLDLALQYGIDSSKIIKTGNWLGPLLVAAAQEKVQQ
LLIFGYHGKLIKLAGGVFHTHHHLADNRLETLIAFAVKERIPLSLIKEFE
EAVSIEAALSILENKDISTAKKLWKRLAVEIEKRSIDYVKRYETSSIEIG
AVMFDRARKIRWAGNYALKQINSFGLKLEDY
>Pro0319 chlD, Protoporphyrin IX Mg-chelatase subunit ChlD
MMVPSEKEPQSISSVLPSLEEANTSFPLAAVTGHGTLKLALMLAAVDPGL
GGVIIAGGRGTGKSVLARGLHALLPPIEVLDLRFAGDLQGPRPFGRNLDP
NFPEEWDDATNELIKQRESNNSANGKQDLQTRVVQAPFVQVPLGITEDRL
VGAVDVASSLDSGSAVFQPGLLAEAHRGVLYIDELNLLDDGIVNLMLAAV
GSGENQVEREGLSLSHPCRPLLIATYNPEEGAVRDHLLDRFAIVLSADQI
ISNEQRVEITESALAFGFSTKEFSKKWDEATQALATQLLLARQWLSDIAL
SQEQIEYLVKEAIRGGVEGHRSELYAARVAKAHAALCGRDKVEAEDLKVA
VRLVIAPRSLQIPPEEEQMEPPPPDEQQPPPPKDESLDEDTEDEDTEDDD
MPEDQSAPPIPEEFMLDPEACAIDPDLLLFSAAKSKSGSSGSRSAVFSDS
RGRYVKPILPKGPVTRIAVDATLRAAAPYQKARREREPGRKVIVQEGDLR
AKLLQKKAGSLVIFLVDASGSMALNRMQSAKGALIRLLTEAYESRDEVSL
IPFRGEQAEVLLPPTRSITAAKRRLETMPCGGGSPLAHGLTQAARVGANA
LSTGDLGQVVVVAITDGRGNIPLGKSLGQPELDGDDSVDLKQEVLDIATR
YRTLGIKLLVIDTERKFIASGIGKDLADAAGGKYVQLPKATDQALASIAM
DAINTVK
>Pro0424 chlG, Chlorophyll synthase 33 kD subunit
MSDTRQLLGIKGGSETTNIWKLRLQLMKPITWIPLLWGVICGAAASGNYH
WNLSNFLASLACMVMSGPLLTGYTQTINDYYDREIDAINEPSRPIPSGAI
SLTQVRIQIWVLLLLGLSFAYGLDRWAGHSSPSVLYLALGGSLVSYIYSA
PPLKLKQNGWLGNYALGASYIALPWWAGQALFGQLTWTTALLTLAYSLAG
LGIAVINDFKSVEGDKKLGLQSLPVVFGIRNASFISAGMIDIFQLAMVGV
LILIGQHLASVILILLIIPQITFQDIWLLRDPLEFDVKYQASAQPFLILG
MLVTALAIGHSSLINI
>Pro0903 chlH, Protoporphyrin IX Mg-chelatase subunit
MFTQVRSANRRVLPVEGQSHKFIMKIVYLVLEPQYQNALTEAAKTLNQQN
GYVGIDLNGYLIEELRDSTNYSDFQADIEKADVFIGSLIFIEDLAQKVVA
AVEPHRDKLKAAVVFPSMPEVMRLNKLGSFSMAQLGQSKSLIGDFMKKRK
EAGGAGFQDSMLKLLNTLPSILKYLPVEKAQDARNFILSFQYWIGGTPEN
LRNFFLLLADKYVIDKNSDKSELEIEVKEPEVFPDLGIWHPLAPKMFEDI
KEYRNWTKSRKDLSDKSLKGPVVGLVLQRSHIVTGDDAHYVAVIQELEYR
GATVIPIFCGGLDFSKPVEEFFYDPEENSTPLVDGVVSLTGFALVGGPAR
QDHPKAIESLKKLNRPYMVALPLVFQTTQEWEGSDLGLHPVQVALQIAIP
ELDGAIEPIVLSGRDDATGKAHTLQDRVDAIAERAIKWSSLRIKPRKSKK
LAITVFSFPPDKGNVGTAAYLNVFGSIHRVLQEMQLKGYEIKDLPKDAKG
LMGRLINDPEALEGSPELTIAHRMSVNEYEKLTPYSERLEENWGKPPGNL
NSDGQNLLIYGCHFGNVFVGVQPTFGYEGDPMRLLYSKSASPHHGFAAYY
TYLEKVWEADAVLHFGTHGSLEFMPGKQMGMSETCYPDSLIGGLPNLYYY
AANNPSEATIAKRRGYASTISYLTPPAENAGLYKGLKELSELVGSYQQLR
ESGRGIQIVNAIIETSKKCNLDKDVKLPETEASALDLEERDSIVGAIYGQ
LMEIESRLLPCGLHTIGMPPTAEEAIASLVSIAALEREQEKIRSLPGLLA
EAIGKDIEEIYKGNNKGELKYVELNKQITDTSREAVRALVLSLTGTNGRV
NLKKSLFTRIIEFIKRLGFNLPSPWFSKCIKNGYKNINIKELDTLFEYLR
FCLNQICADKEMDSLLRALDGDYVLPGPGGDPIRNPNVLPSGKNIHALDP
QSIPTVAAVASAKGVVDKLIEKQKEEQGTWPETIACVLWGTDNIKTYGES
LAQILWFVGVKPKPDSVGRVNKLELIPLEELGRPRIDVVVNCSGVFRDLF
INQMALIDQAVKMAAEANEPIEDNFVRKHSLQQSESEGISLREASCRVFS
NSSGSYSSNVNLAVENSTWEEENELQEMYLSRKTYAFDADNPGEMNQNRE
VFESVMKTADVTFQNLDSSEISLTDVSHYFDSDPTNLISKLRDDGKKPNS
YIADTTTANAQVRSLSETIRLDSRTKLLNPKWYEGMLNSGYEGVREVSNR
LNYTLGWSATSGQVDNFVYEESNETFINDPEMRKRLMELNPHSFRRIVGT
LLEVNGRGYWDTSEENIDRLKELYQEVEDKIEGVDTD
>Pro1146 chlI, Protoporphyrin IX Mg-chelatase subunit ChlI
MSSPRKRRVFPFAAVIGQSEMKLALLLNVIDPRIGGVMIMGDRGTGKSTT
IRALADLLPAIKVVEGDPYNSSPDDPDLQSSDVREQIDQGTTPSTENKQV
PMVDLPLGATEDRLCGTIDIEKALSEGVRAFEPGLLAKANRGLLYVDEVN
LLDDHLVDVLLDSAASGWNTVEREGISIRHPARFVLIGSGNPEEGELRPQ
LLDRFGMSVEVRTVREPELRVKVVDQRTSFDNDPENFVSSIQSSQDELQA
KVVAAQELLQSVNIDDDLRLKISAICGELDVDGLRGDIVTNRSARALAAF
EARSEVTEEDIARVISCSLRHRLRKDPLEQIDSGDRVIKAFCKIFERSDQ
ANLADFELAAIE
>Pro0193 chlM, Magnesium-protoporphyrin IX methyltransferase
MQVEGLQKLKESEKAEVATYFNGTGFERWNRIYSKSDEVNKVQKNIRIGH
QKTVDDVLTWIKEIGEISDMSFCDAGCGVGSLCLPLVALGAGSVSASDIS
EAMVEETQRRAKIGGLDLNRLNFKISDLESLNGSFDTVICLDVFIHYPQK
AAEEMVHHLCGLSKKSLIVSFAPYTPLLALLKTIGQFFPGPSKTTRAYIL
REKGIINAARACGFEVKRRKLNQAPFYFSQLIEFVKK
>Pro1626 cioA, Adenosylmethionine-8-amino-7-oxononanoateaminotr ansferase
MDKAMDNILSYPENWHQNIWPPFTQITSSRPPLQISNAKGCLIFKDNGEP
IIDAISSWWVTLHGHSDPYIASAIYNQAKQLEQVIFADFVHPQAELLAKR
LSQATGLQRLFFSDNGSTAVEVALKIALQYWHNKGEQRHHIIAFEGAYHG
DTFGAMSVGERNLFNEPFKEMLFPVSRATWPSTWWGDEGIERREEEAIKK
LEIMLERPTAAVILEPLIQGAGGMTMVRPEFLQAVQGVVRQAKALLIADE
VMVGFARTGSLFASQRAKISPDLMALSKGLTGGFLPMGITMASQEIYNTF
LGNDPQKTFWHGHSFTANPLGCAAANASLDLLERNPTAYTNFESRHLPHL
EQLVKHPKIKKIRLTGTIAAFDLKTDGNDGYLNNTGKVIKAYALANNVFI
RPLGNVIYLLPPLCISDHQLEQCYKVIKSSLDII
>Pro1102 cioB, Biotin synthase
MTLLNPNIPIRQEVKVRFDWSLEEIQEILEKPLFELLWEAQNVHRSVNPE
YKVQLASLLSVKTGGCEEDCSYCSQSIYNSSDVTNQSDFDVKGVLEQAKA
AKAAGADRFCMGWAWREIRDGKPFEAMLDMVRGVKELGLEACVTGGMLTN
QQAARLAEVGLNAYNHNLDTSPEHYDKIISTRTYQDRLETLHRVRNAGIT
ICCGGIIGMGETLKDRASLLRVLANMDPHPESVPINALVPVEGTPLENLS
MVDPLEMVRMVATARILMPRSRVRLSAGREQLGKEAQILCLLAGADSIFY
GDTLLTTSNPSIKADRELLASAGVSVNWDLYD
>Pro1625 cioD, Dethiobiotin synthetase
MNIKSLKVVVCGTDTDVGKTVVSSLLVQGLSGVYWKPIQSGLEGGGDTNR
VCELLTLPKERWIPEKYKFKAAVSPHWAAEQEHIIIKPNLLKVPLVNQSL
IIETAGGVMVPLTRQYLQIDLLKEWMLPIIIVARSGLGTLNHTLLSIEAL
TKRKIPILGLIINGPLHKDNPKTLEQFGGVPVIAQLPKLASLSASSLAKE
WLKQDIRNRLEQLLETTNR
>Pro1622 cioF, 7-keto-8-aminopelargonate synthetase
MKKIPKTRIRKIRTWIPKAKAGRLLENINDKQFSSLLDLASNDYLGLSQH
PNLIEAAKETMIAEGLGAGGSRLVTGSRPIHQALEKELSQWLNFESVLLF
PSGFQANLAAVTTLANRKTPVIADKLIHHSLLVGIKASGAKLKRFSHNDI
NDLEKLIKISLKESPTQTPLVITESVFSMEGSSPDLEKIGELCNNYHAML
LVDEAHSLGVMGDQGRGLCYGLKNPVTMISGTFGKAFGGGGAFLATSDFY
GEHIVQTSGAFRYTTALAPPLAAAALEALKLIKDNPGWGLALQKKSSLWR
STLIEHGWNVRIGNSPIIPLVLGSDEESLKKQTELEANGILTVAIRPPTV
PEGTSRLRIVVRNNLPGEVLEQLLFYLGKKV
>Pro0429 cirA, Biotin-(acetyl-CoA carboxylase) ligase
MQNSLPWTGAAPITCLIKRSEVLKKSWVLRWKPVCGSTDIELSRWLKQKP
LSVNNPRAFLTGRQSHGRGQRGRIWDSPLGGVWLSAAMTCDVSVKSAGLF
GLAVAVALSNRLERSLIPVQIKWPNDLLVNGKKIAGLLPRVFSRGQEANF
LSLGIGLNVCNHVPKGGISLLKCSGKKNISTLKWSLEVLLAIEQAKMLLL
DPKHLCKEGEKFLWAKQIKKSQSNEIWDVEGLDLDGKLRVSRGFIKENWN
RWE
>Pro1746 cmk, Cytidylate kinase
MNLTILRTKTALEDWCRQKHNHEINFVPTMGGLHQGHQELIKTARSFCKR
KHSSQVLVSIFINPLQFDLEEDFKKYPRTFENDCKIAYEAGANAIWAPSF
ESVFPNGEEAHFKIQVPFSLNKYLCGASREGHFDGVATVVVRLLALVRPN
RIFLGEKDWQQLVILRQLINDLGLPVLIHSIPTKRDQDGLPCSSRNVNLS
KEERKKVVALPAVLQQAAQAFQENKPINLNNMKTTLEEHDLKVEYLETVD
LKNLNPVNHDESKLCLLAAAVHCGNTRLIDHGFLMKRNPIVAIDGPAGAG
KSTVTKKFAQKLGLIYLDTGAMYRAVTWLIQENNIDPQNSSELELILNDI
NLDICLSNTGNQQVLINGKDITTLIRSPTVTSQVSLVAAIGSVREKLTSQ
QKELGSKGGLVAEGRDIGTAVFPDAELKIFLTATAQERAKRRAIDLKKQG
FSTPSLSELEKQIKERDRLDSSREIAPLSKAKDAQELITDGMNIEEVVEL
LINIFREKIPQEVWPTNAT
>Pro0952 coaD, Phosphopantetheine adenylyltransferase
MKVLYPGSFDPLTLGHLDLIHRASVLYEEVIIAVLENSTKSPTFSVSRRI
EQIKESTKELSKIKILSYKGLTVECAKSLDVDFILRGLRAMSDFEYELQI
AHTNRSIDKSIETIFLATEARHSFLSSSVVKEVAMFGGNIDHMVPAIVAK
DLYKIYKQGDI
>Pro0053 coaE, Dephospho-CoA kinase
MRVSKANALKRWKGSQRRIGITGGIASGKTSIGKYIESVKNTPILDADMF
SREALTANQTIKDTIINRYGRTIVDKENTNSKTINRAALGEIIFHDKNER
IWLENLLHPIIEKRFEEELEKHKLSSTIVLIIPLLFEANFTYLCSEVWLI
YCSLDEQYERLMKRDGLNKEQAKYRIEAQLPLESKKILSDHIIDNTNKLD
LSYPQVEVLL
>Pro1126 cobB, Cobyrinic acid a,c-diamide synthase
MAFVIAAPASSNGKTLLSILIASWARRNGESTQTFKIGPDYLDPQLLSAV
TERPCRNLDTILCGKNWVVNSFNLYGSAAEYAFIEGVMGLFDGIGSSDKG
STADIARLLNLPLLLVVDARGQAGSIAALVKGFKDFDHTLNIAGVVLNKV
NSSRHKVLLTEALTKINVKVLGCLPKDDYLSIPSRSLGLQPAHEISNIEK
LINTWASIAEKNLDFCSLRPLLKAPSQSNSLSNILFKNNLKNPRLKRTTI
AIAEDKAFHFRYPETKECLEELGINLIKWQITQDSPIPKQAKGLIIPGGF
PEQFAEEISQCKRSLNSIKEFLNNYPIYAECGGMLILGKSLSDTNEKKFP
MAGILPFNAKEGKLKVGYRKLTAISNSLISNKGDLINGHEFHRWKLDING
SNDLDITKKEPMIQSSMNLYSPWEIRGWGIDTRQEGWSNKNFHASWIHLH
WASSPSILQNWSSIVHKHI
>Pro0386 cobF, Precorrin-2 methylase
MEIVNIYKRILSIFNPSLSSLKSKTGITFVGVGPGDPKLLTIAAVEAIKK
ATLVAYPVAKLGSKSMASEIACSFIKNKKCLPIVFPMITDNEALKRAWAF
GANKLIEEVKKGEEVVLLSQGDPSLYSTSAYILLEIKSNFPLIPLKVIPG
ISSFNAAAAEAQFPLSLQKEELLICAVPDNPNHLKEMLDNAIKTKRVLVL
IKLGKRWEWVRKVLDEKGLLTKTLFAKRIGFADQLTIKANNISNEEAPYF
SLLIIREDAIF
>Pro1806 cobH, Precorrin isomerase
MTTIDHPIFDESVRFIRSRLHCPELDKLEVQVLERLIHTTGDFGIQDYLT
FSPNACQLGVAALQAGAPILTDTFMAAAAVNPMASRTMQSSVHCILDWAP
KKGHSGLTRTALGIESAWTDLSKNFNNESSPIILFGSAPKALEVLLGLIA
NGALSPSLIIGMPVGFISVLESKMLLSQMDLPQIRIDGNRGGAAMAAATV
NALLRASWNIKQTNKKLSAE
>Pro1671 cobJ, Precorrin-3B methylase
MLRLKARGHVDSIALSPKAAAQVDLFGSKCLVHKPEDIFQRFWEPRAAFI
VVGAIGAVVRMIAPLITDKESDPAVVVMDSRAQNIVSLLGGHQAGADELA
CQLAEDFGGHFVSTGFSRTEENIALDSFGDAWGWRRKGDISDWKNLMILI
ALKEPIKVEQTSGSLLWKTMEGAINTLEGSKNQKDIPKSHLMKISSQKSP
QCCWHPATLWVGIGCERNTSYGLVTRALEAALEEACLAREAIAGLATIDI
KYDEPAIKSLRSKYFFPLRLYSAQDLSQIDVPNPSRIVDSEVGTPSVAEA
ASILAAGERGILKFQKHIYTSNKSEKGSVTIAIAEAIEPFAPTRGELHLV
GSGPGDPSFLTNDSRLALARSAVWIGYKPYLDLLEPIRKFDQARIDSFLT
NERDRCEQALNLATQGIRVSLISSGDSGIYGMAGLALELWLERPKEDRPE
FKVHPGISSIQLAAARIGAPLMHDFCAISLSDCLTPWEQIEERVRAASIS
DFVIAFYNPKSKSRNWQLQKAFEILLQNKPLHTPIAFARQLGRADETVEV
HTIGSFPIDRVDMLTLLLVGNSKSFFKDGCLVTPRGY
>Pro0503 cobK, Precorrin-6x reductase
MHMRRNYHRHIWILSGTGDGPPLVRILLQNGWKVSVSVVSSQAALAYGDL
PLESLWIGPLEGTQAIANVIEKARATHKGFDWIIDATHPFAQVISSNLNV
VSRKHKQPLLRFDRCCKKSQNASLIKNYCELLKLNLSEERILFAIGSRHL
PEALSCGRKAGATVFARVMPTVEGLRKALMCEIPQSHLAVFKPLASDEIG
EIESALCRRWKITGVVARESGGSTQKIWQNISLQQGLKLWLIARPALSKN
IKVVNTFAELLAEI
>Pro1342 cobL, Precorrin-6B methylase 2
MLRNNINSDKAFLPINVVGVTASGVFGLPLELQQLILSAKNISAPKRILN
NFVEWWEHQAANAPSPELFPSDKPNELIEWLKQRNQKTVLLASGDPLWFG
IGRVLLNHFPSEQLIFHPSPTSLQLAFAQLKRPWQDTSWISLHGRDASPL
FNLLQQRPNAIGILIDPNKGGANEVREILHSSELEDQYAFWIFEKLGHKE
ERIFRIFSNEKLSKLDPLHLVVLIKEKKIIKTKKELPLFGIEDGFYLQHA
DRPGLMTKREVRTQVLADLELPETGVIWDIGAGVGTIGLEALRLRPNLKL
LMIEKRIGGKELINENAKRLSVKPEIVIEGEALNFLEKESIPIHISKPNR
VILGGGNSRKDTLLKIILSFIQPLGIIVIPLATLEHLEKTILVLKEAGCD
VKISQHQNFRGVPLMQGTRLLPMNPVFIIKGKLK
>Pro0457 cobM, Precorrin-4 methylase
MNKIAIVGAGPGSADLLTLRALNRLQNAEVLIWTDSLISPEIAELTSKTC
EKFATSSLTLEEILALLISKAQQGKRVVRLHDGDPCLYGAISEQIYALAE
EGIDVEIIPGISAYQATASELKKELTIPGIVQTIVLSRSGGRTGIPEAEK
LENLAKIGASLCLYLSARHVEDVQKTLLTYYPKDTPVAIGYRVTWKDQWL
KIVPLNQMAAASRDKGLFRTTLYIISPALKSHDKRSKLYSDEHKHLFRKK
>Pro0957 cobN, Cobalamin biosynthesis protein CobN
MHRIANLPSEESTENLALLEQPQAPVLFLTSAASDISTLSYILNENKNHA
LKDKIRALKIDFLLHNAQVDHYLTTTGSKAQIIVVRYLGRRSDWSYGFEQ
LYYWSKEDKNRHLIILSGVEEQETELNSIGNITFPLSLKLGKLLRIGGFS
NMKTFLAIISKILTCEIVNFKNIKIANIDDPCRWEWTDVKGPKIGLILYS
SILNSGDSNLAISIIKILRQKGLNPRPLWVSSLKKKHVQSKVLDIYKEEN
VRCVLTTTSFASVNFDQASEGKQIWDLLGVPVIQILSSNKQKKEWKDSSR
GLDPLDLSLQVVMPELDGRITTKIGGFKKVVEQNLNLYSPVYRINPDKEN
IKWIADYTKSWVSLQKKDKQEVKIIINLSNYPIKDGRIANGVGLDSPESI
VVLLEQLKLNGYYLGNKPIPSNSKQLMKLIINGRTNSLESSNNEPLEYIS
LDQYLKFWSTFSLTAKQKIKLNWNKPSLSIDLEKKGFPVNGIRFGNIAIL
IQPSRGYTEDNINDIHSPTLAPPHRYIAQYFWIYKFFKADVMIHMGKHGT
AEWLPGKSVGLSSSCFPQLVIPPIPYLYPFIVNDPGEGSQAKRRTHSIIV
DHLTPPLARAGLSQQLIDLENLLDEYYETLLLDSDRNKIVKEKLDSIIIK
ENFDSIISTKDKLNNKVDSIYENLDSYLCELKESQIRTGLHILGRMPSDS
KLGELTLAIAMAPTFNTSGISQYLSRLLNINIDPWADNEGDSISEVDNNR
LFDLNQLKFRIKGDYITWINNQAQSVVSYYLRKALNKRDINCIPNNLINE
LRPLLLPGPLPLEIYKIKESLIPSILKSPSNEIKSLFKGINGLRVSSGPS
GSPTRGNVEVLPTGKNFYSVDLRCLPTQSAWDLGRKSAEQLCEIYLLEKG
IHMSNLAMSVWATSTMRNGGEDICQFLSFLGIRPVWDNNTKKLIDLEVIP
LQILGRPRVDVTLRISGLFRDAFPNLIELVNKALDMILNIDEPLELNPLL
KSSKNGEYISRIFGSSPEGYGTGLQELINIGIWEETSELANCYLKSSQWE
YTNSKEPTLNLNGLKESLKKIQVVLHSQDNREHDLLDSDDYYQFHGGLSA
AVKELSGICPDIYFGDNSRKNKPRIHKLEKEIDKVVRSRLLNNKWIEGMK
EHGYKGAFELSASLDYLFAYDATTGSVPKWCYSSIREQWLDNDSTKNFLI
EQNPWVLRDISERFLEAYNRKMWSASKSELNKIKRLLLEAEKTIEESNY
>Pro1259 cobQ, Cobyric acid synthase
MKNISAGHNALMVLGTSSGAGKSIITTAICRSLLRKGEVPIPFKGQNMSN
NAWVDINNGEMAYSQAVQAWAAGIEPICAMNPVLLKPQGDCTSEVIHLGK
SVGVVQAANYYEDWFSSGWEAIQKGLNDIATSYKKHRLILEGAGSPVEIN
LQHRDLTNLKLAKHLNAKCVLVADIERGGVFAQIIGTLALLKPDEKALIQ
GIIINRFRGDISLFEKGRQWIEEESKIPVLGIMPWLNEIFPPEDSLDLLE
RKHKKTKAEIQIAVIKLPSLSNFADLDPLEAEPTIQLNWIQPGDYLGNPN
AVIIPGSKQTLKDLQSLQSSGLGNQIKEFASSGGTVFGICGGLQILGEKL
EDPLGIEQSFLETSISELEGLSLIPIKTIFHSKKSLTKKDVISKWPDESR
IMGFELHHGESTPTNSQKVKVKDLCNETSLGWVNEECNPIKAAGTYLHGI
FDNGTWRRLWINQIRKKANLYELPLLEENHDAKREKVINRLTDVFEENIN
LEYLLKT
>Pro0302 cobS, Cobalamin-5-phosphate synthase
MSSPNWLKDLTGAWLFYTVFPKLTRINPRFERIARFSPLIGVLIGVLQVS
VLILLLQLQWPNESMPFIAIALGLWITGGIHVDGLMDTADGIAAGPSRCI
EAMKDSRIGASGIIALTINLLLQIAALFKLRLLILFAIPIASFWGRYSQI
WAISHYPYLNKEGSSKFLHKKNWRGFLIESIPSYAFLSFLIFILINIDIS
IISTPNLIIGIIVGFLPALIIPHLLARRLGGHSGDSYGASVVLVETCMLI
IFSIILPAS
>Pro0435 cobT, NaMN:DMB phosphoribosyltransferase
MNQFESTQSNIFSLRSSDRCNVFGSSSSSPSLLNRWIDIWSTSISDITSI
LVLAGTKTAEIEGISAAGATKESRRFTAVADAEFLLHGPTASRRWPLPPL
SAGVSPALISYVASDLIGVKSLIAQAGILQTPSFPCLSIESPSQGPSECI
TTGKAMDINRVENLFEEGMKMGLELASPLLLTECVPGGTTTALAVLTGLG
ITASELISGSSRTPPMTLKKKIVEKGLQSLSLGAKPCPKELLAAVGDPFQ
PFAVGLLLGARKVKQPVLLGGGSQMLAVLATALASIDSSLKDDFVEDISI
GTTYWLANESLSLSIGQSAFQSLIKLVEDSFEVSLLGLSAGLRFTKSSKQ
VLRDYEIGYVKEGVGAGAFVLLAQNNGVSCKKLIEECEFAVDQLDKI
>Pro0974 cobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase
MINKRNKNNLILVSGPIKSGKSRWAEKLIFKEKNVTYIATHEVIYDNKDW
IERIRLHKQRRPSHWQLIETSDISSSLKSIDKGNSILIDSLGGVVSKYLN
YDSVKWNTYSSLIIEKLTKFEGVIVIVAEEIGWGVSPYTESGNIFRDRLS
ELTEKLDTYAKQSWLVIHGRAINISINSSRI
>Pro1042 crtE, Geranylgeranyl pyrophosphate synthase
MATVTELLQPIEIDLEHLLKDLRDLIGAGHPILQAAAEHLFSAGGKRIRP
GIVLLISKALSAEGELSSKHRRLAEITEMIHTASLVHDDVLDEASTRRGV
DTVHNRFDHKVAVLAGDFLFAQASWHLANLDNLDVVKLLSRVIMDLAEGE
VKQGIYRFDPNQSLDVYLEKSYCKTASLIANSAQAVGVLSNESDYHLKCL
YNFGKQLGLAFQVVDDILDFTSDDKQLGKPAASDLSAGYLTAPALYALEE
NPSFKELIIREFSNEGDLDHAMELVRESNAIIRSRKLAENFAKNSYESIK
WMPDSPSKRALLDLPEYVLGRLF
>Pro1725 ctuR, ATP:corrinoid adenosyltransferase
MESNQDSNTSVRNDKSSVIGRKKSIGIVTAADSKERSHGQLHVYDGEGKG
KSQAALGVVLRTIGLGICEERRTRVLLLRFLKGPGRSYDEDAAIEALQQG
FPHLIDQVRTGRADFFTAEEATRFDQTEAKRGWDIAKGAIASALYSVVVL
DELNPVLDLGLLAIEEVVKTIASRPAGMEIIVTGRAAPRPLIQIAELHSE
MRAHRRPHGDNVYAIANGSPGGIEIYTGEGKGKSTSALGKALQAIGKGIS
QDKSHRVLILQWLKGGNGYTEDAAIAALRESYPHLVDHLRSARDAIVWRG
QQQPIDYVEAERAWEIARAAISSGLYKTVILDELNPTVDLELLPVEPIVE
TLLRKPAETEVIITGRCKNHPPYFDLASVHSEMVCHKHYAEKGIDLKRGV
DY
>Pro0523 ctuR, ATP:corrinoid adenosyltransferase
MQKKMAKSDESLDELDRESSQLGMGGFTTKEADEEKYKLRMQRRKEIQSK
RIEERNLEKGLIIVFTGQGKGKTTAALGMALRTLGHGDNVAIVQFIKGGW
QPGEAKALKVYGDSLDWHAFGEGFTWETQDRMQDKKLSQKAWEQALLYLC
SRSHKLVILDEINIAIKLGYLSLNEVIEGIKKRPALTHVVLTGRSAKEEL
IQQADLVTEMNLLKHPFREKGVKAQKGIEF
>Pro0275 ctuR, ATP:corrinoid adenosyltransferase
MSASPSSTNDYSTREQYGIGPISSISSKPRLQIISSQGQLQVYASPYRGS
FSAVLSEALRSAGLGSKVVIAQFLKGGVAQGPINSTSLCGNLEWIRPNIY
GCIQKNPNSQADLSEESTKTKTAIEEIWKICKEHLINNSLDKLVLDEIGL
AIEYGFLTETDLIHSLENRHDSIDVILTGPSIPTRVFSMADQVTQLRCSK
>Pro1858 cysG, Uroporphyrin-III c-methyltransferase
MKDKQLGTVYLVGAGPGDPDLLTVRAHRLLSQCDVLVYDALVPDEILKLV
KKDCKSIFVGKLRGHHSTSQLKTNALLLELVKKNKCVVRLKGGDPFVFGR
GGEEAAYLHKNGIGVEVVPAITSGIAASAYFGIPLTHRIASSSVTFVTGH
EGIDKRRPSVNWKALAKASNTLVIYMGVHNLSYIVKELLAAGLSPKIPSA
VIQQATVNGQRCLRTSLDSLVKEVKEQEFISPSIIIIGETINFQIEACAP
SPAKVTMPISF
>Pro0095 cysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)
MDDKHMTSRKLEKIPFLKIPLKEARKHLEPLSPQKRLTWAYEQFGPHLAI
TTSFGIQSSVLLHMLYQLNSGNTIKVIWVDTGYLPKETYQYAAALTDRLK
LDVTVAQSIITPARMEALYGELWNTNSLKDMGKYHRIRKVEPLEKALEDL
DIYCWASGVRSSQTDNRSSMSILDRIRNRLSLRPILEWSQKDIFYYMQTN
DLPQHPLFEKGYSTIGDWHSSSPDTTDAAGRKTRFGGLQQECGIHIEDSN
KEHK
>Pro0258 dfp, Phosphopantothenoylcysteinesynthetase/decarboxyl ase
MKTKVNNNLNGKKILVITTGSIAAVKIPLLVSNLIKTGAEVRCVVSPSAS
KLVSPLSLSTLSRNACYQDEDQWNRREPRPLHISLSEWADLIAVAPLSAS
SLSRWVHGLSEGLAASILLASEKPVIAAAAMNTAMWNNSSIKNNWETLKN
FPNVIPLTPAEGLLACDRIGDGRMADPLLIQLAIESAIIQFRANSALHKD
WSNLKLLVTAGPTIEDIDRARYLTNRSTGKMGVLIGQAARFRGATVDLIH
GPIQVEAALLEGLQTFAVRNSNEMYSILEDLQSSADAIAMTAAIADLKPL
VNTKNIKLSKEELFKSMKDRFEIVPDLLSKLIANRKNNQVFLGFTALTGN
DEKIKELAMLKKKQKKCDLLMANPIDRSNQGFESDSNGGWLLGPEEAINE
IKIGSKLSVAHQLLDELKSVLINKLKNK
>Pro0928 dxs, Deoxyxylulose-5-phosphate synthase
MRLSDVSHPNQLHGLTTAQLEDVACQIRERHLQVVSTSGGHLGPGLGVVE
LTLALYQTLDLDHDKVVWDVGHQAYPHKLLTGRYGDFDSLRQQNGVAGYL
KRSESSFDHFGAGHASTSISAALGMALARDRQGKDYKCVAVIGDGALTGG
MALEAINHAGHLPSTPFLVVLNDNDMSISPPVGALSTHLNRMRHSAPIQF
ISDSVQEGVRNIPFIGKEIPQEIKSLTGSVKRLAVPKVGAVFEELGFTYM
GPVDGHDIAQMTRTFQAAHRIGGPVLVHVATTKGKGYPYAEADQVGYHAQ
SAFDLTTGKSIPSKTPKPPSYSKVFGQTLVKICEQNSKVVGITAAMATGT
GLDLLQKAIPDQYIDVGIAEQHAVTLAAGMACDGLRPVCAIYSTFLQRAF
DQLIHDVGIQNLPVTFVMDRAGIVGADGPTHQGQYDISYLRSIPNFTVMA
PKDEAELQRMLVTCLSHDGPTALRIPRGPGEGVTLMEEGWDPLKIGRGEI
LSEGSDLLIIAYGSMVAPAQKTALCLKESGISATVINARFLRPLDQGLIH
PLARRIGKVVTMEEGTLLGGFGSAIVESFADQDIAVSTYRIGIPDKLVHH
ASPQQSKEELGLTPTAMADNIKKRFGWDNSDSLFVKNSNTSTI
>Pro1376 folC, Folylpolyglutamate synthase
MNLINYKENNDFEELIPSFKSKGMNLGLDRIQNALQKMGNPCHKVPAIQI
AGTNGKGSITCFLESCLTKTHIKTGCTTSPHLVSWCERIRIDGQMISPEK
LRKFVNEVKLITKSEQLTPFELVIASAFNYFFVNQVELILLEVGLGGRLD
ATTAHPWRPIIAMGKISFDHCEYLGESLAKITKEKAAVISYGSHVISADQ
EPEVKKILEDTVLKKNAKISWVSPLSKQWELGIAGEIQRENAAVAKAVLE
SLPTFGWKINNNQIKKGLASANWPGRLQSTKWEGLPLILDGAHNPEAIRQ
LSKERALWVNQSSIVHWIIGIQTNKNAPEMLRNLLKEKDIAWIVQIPNHQ
SWSKDQLLKACPELSHQLRKAESILKVLELLRSNNQWPTPPPIVTGSLYL
IGDLIKNKIIT
>Pro1130 folD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase
MTNILDGKKLAKELELRLHEDITEFSPEVGRPPGLAVIRVGDDPASGIYV
SNKEKACNRIGLDSFLYHLGTNTSEQEILEVIKALNNDQKVDGILLQLPL
PKGLDAEPLLKAIDPEKDVDGLHTLNLGRLLKGEKGPRSCTPAGIMVLLR
RNNISLVGKKVVVIGRSILVGKPMALMLQAANATVTVAHSKTINLPEITN
QAEVLIVAAGIPQLIGLEHVRSNAVVVDVGIHRIPMEPLKLTGSNYKLCG
DVRAEEIYSKIKAITPVPGGVGPMTVAMLMVNTVNRWQYHCGLSSTLSDL
LP
>Pro1579 folE, GTP cyclohydrolase I
MTSTAPDEDVKDDIKEKISCKLVSEIIRERIESAGARFHANDNISNYILP
GELKTLEKEVSTRVRDLLKTLLIDVDNDHNTQETAERVSRMYINEVFKGR
FYEQPKVTSFPNDKNLDEIYTVGPITVRSACSHHLVPILGDCWIGIKPGE
KVIGLSKFARVADWVFSRPHIQEEAVMILADEIERLCEPKGLGIIVKAQH
YCMKWRGVKEPDTSMINSVVRGDFRHDSSLKQEFFELVRQQSNANKNY
>Pro0537 folE, GTP cyclohydrolase I
MEKEVSVRIKDLLKSLVIDIDNDHNTRETPERVARIYINEVFKGRYHKQP
KVTSFPNVKHLDEIYTVGPICVRSACSHHFVPIMGNCWIGIKPGARVIGL
SKFSRVADWVFSRPHIQEEAVMILADEIEKLCEPQGLGIIIKADHYCMKL
RGVKESQCSMVNSVVRGDFRHDSSLKQEFFELVRQQETALSR
>Pro0318 folK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokin ase
MSSINYLISKTLAIGLGANIESPAGSPAKTLITARPLLENTITSWIKKSL
KNASKNSIEDSTIDFSWSPLYRTAPLGGPKTQPSFINAALVIREGGLNQL
IPSVEAARDLLNNLLLLEKHFGRDREISKIHWGPRSLDLDILAWGDLQIN
DSDLILPHPYLIERDFVIIPLAQALVKKSSSPIQIPSQKGWPE
>Pro0123 folP, Dihydropteroate synthase
MKQILSQKEQFINNLDEKYSQRFIELDPSGYFLIKVSHETNELIVEHFSN
NIDETGLATDPETGEPLKCNDNKERSPIKVFKGKSAKEIGIQITEGHVPK
PLTKLDHALYLGRELQKAEFCLTNGKPYVQD
>Pro0902 folP, Dihydropteroate synthase and related enzymes
MGVINVTPDSFSDGGEYLEPLEAYKKASECIAAGVDVIDVGGQSTRPGAK
TISPEKELQRIMPMLKLLRKNFPNILISVDTFYSKVAKEVIEIGVDWIND
ISGGRLDPKIRNVVASSNCPYVITHSRGNSFDMNNYAFYNDVVEEVYMEL
MQNVEEALAAGISNKLILIDPGLGFAKNNIHNLTLLSNLEKFTDSQYPVL
VGPSRKRFIGHVINEPDARKRIFGTAAVTCRCVQAKVDIIRVHDIKEINQ
TIKMATSLWPF
>Pro0841 hemA, Glutamyl-tRNA reductase
MNIAVVGLSHRTAPVEVREKLSISDEHIEKSFCSLNATEQVLEVSILSTC
NRLEIYALVKNQELGVSAIKEFLIDHSGLSKEDLFPHLFTFNQAEAVNHL
MRVSGGLDSLVLGEGQILSQVKKMVRLGQDYKSIGPILNRLLTQAVSTGK
KVRSDTNLGTGAVSISSAAVELAQLKLGQSLGKDQLMTLQSEKVAVIGAG
RMSRLLIQHLQSKGCSKLTLLNRTLNRAESLAKDFPDLDVKCGLLDDLDK
CIEFSTLIFTSTASNTPIINSELLSGFKRNNNLLRLIDIGVPRNIASDVS
GLPGFEAYDVDDLQEVVARNQDARQQIAIEAQNLIDEEARVFLEWWASLE
AVPTINRLRSNLESIRKEELQKALSRMGPDFSARERKVVEALSKGIINKI
LHTPVTNLRAPQPSSQRKESLKIVESLFELGVSENDQ
>Pro0243 hemB, Delta-aminolevulinic acid dehydratase
MELTYRPRRLRRTTALRSMVQEHSVHASDFIYPLFIHEGAEVQPIGAMPG
ANRWTLDTVVGEVTRAWNLGVRCVVLFPKIDEELKTEEGEECFNEKGLIP
RAIRRLKTELPEMAIMTDVALDPYSLDGHDGIVSSEGVVLNDETVSQLCK
QAIVQAAAGADLIGPSDMMDGRVGAIREALDEEGYENVGIISYTAKYSSA
YYGPFREALDSAPRAINNSKPIPKDKNTYQMNPANAREAITEAQLDEQEG
SDILMVKPGLAYLDIIYRLRQESELPIAAYNVSGEYSMIKAAALQGWIDE
KSVVLETLLSFKRAGADLILTYHACDAAEWLNDK
>Pro0494 hemC, Porphobilinogen deaminase
MALDQVRIASRRSQLAMVQTNWVKEELEKACPSIDISIEAMATQGDKILD
VALAKIGDKGLFTKELEAQMLIGRADIAVHSLKDLPTNLPEGLMLGCITK
REDPADALVVNKKYKNYQLNDLPEGSVVGTSSLRRLAQLRHHYPGLIFKD
VRGNVITRLEKLDSGEYDCLILAAAGLTRLGFGNRIHQLIPSEISLHAVG
QGALGIECVKDKEEILQIIKVLEHKESSLRCLAERAFLKELEGGCQVPIG
VNSKIQGQELILTGMVASLDGKQLIRDTKTGSSMHPETIGIELANTLKSQ
GAMEILEVIFKEARA
>Pro0134 hemD, Uroporphyrin-III synthase
MSIDPNLPLSGKTVVLTRSQDQQAEARILFEEQGAKVLDMPALVIGPPDD
WTLLDKALLDLNNFDWIIFSSANGVKAVDERMKFAGSSLSNKPKNLNIAA
MGRKTAEKLKLLNLIPDFVPPEFIADSFLKHFPLSRTSLRVLIPRVQTGG
RTLLAETLSDAGASVMEVPAYESTCPKNIPIETVNAINNGKVDLIVFSSA
KTAFHTSKLLQKFFGHKWKEILLEVKIISIGPQTSINCKKYFDRLDGEAI
KHDLNGLVQACIQSIKV
>Pro1079 hemE, Uroporphyrinogen decarboxylase
MTDSLPLLLRAARGESVNRPPVWMMRQAGRYMKVYRELRDNHPSFRERSE
NPDLSYEISMQPFREFKPDGVILFSDILTPLPGMGIDFDIVESKGPLIND
PIRTLEQVKTLRPLEPQVSLPFVGEVLGRLRESVKNEAAVLGFVGAPWTL
AAYVVEGKSSKNYSVIKAMAFQQPDLLHKLLNHFAESIANYLKYQIESGA
QVVQMFDSWAGQLSPIDYDNYAAPYQKKVVDLVKQSHPDTPMILYISGSA
GVIERMAKTGVDIVSLDWTVDMAEGCARLPNNIGIQGNVDPGILFGTPKM
IQERIIDTVKKAKGRKHILNLGHGILPGTPEENAKVFFETGKNINNLISN
I
>Pro1737 hemF, Coproporphyrinogen oxidase III
MSLSQPSTQSRVKVKSFLTGLQDDICKGLENIDGEGTFQEESWERPEGGG
GRSRVMREGRIFEQGGVNFSEVHGEELPPSILNQRPEAKGHKWFATGTSM
VLHPRNPYIPTVHLNYRYFEAGPVWWFGGGADLTPYYPYLKDTRHFHKIH
QEACDSINPKLHKVFKPWCDEYFFLKHRNESRGVGGIFFDYQDGSGKLYK
GQNPNGLSSIASKELGEYKLSWEDLFSLAKACGNAFLPSYIPIIEKRHNQ
TFSDRERNFQLYRRGRYVEFNLVWDRGTIFGLQTNGRTESILMSLPPLAR
WEYGFKAPPESRESLLTDVFTKPQEWFTDESLEEKCRPHHAVD
>Pro0525 hemH, HLIP-like domain-containing ferrochelatase
MTRVGVLLMNLGGPERIKDVGPFLYNLFSDPEIIRLPLPIFQKPLAWFIS
TLRSSKSQKAYQAIGGGSPLRRITEQQARELQSALRNRGINATSYVAMRY
WHPFTESAVEDIKADNINEVVVLPLYPHFSISTSGSSFRELRRLREVDKE
FQKLSIRCIRSWFDNTGYIASMAELIEQEISSCESPNAAHICFTAHGVPK
SYVEEAGDPYKDEIQDCALLIIDKVEKSLGFSNSYTLSYQSRVGPEEWLK
PYTEEVLEELGANGVKELIVVPISFVSEHIETLQEIDIEYKKIALNNGII
NFRRVKALDTYPLFINGLADLVASCLSGPEISLDEAAKLPEKVKLYPQEK
WQWGWNNSAEVWNGRVAMFVFIICFFELVIGNGPLHYIGLL
>Pro0482 hemL, Glutamate-1-semialdehyde 2,1-aminomutase
MTNAFNTSNSQAVFHAAQELMPGGVSSPVRAFKSVNGDPIVFDRVKGAYA
WDLDGNRFIDYVGSWGPAICGHSHPEVIASLQEALEKGTSFGAPCELENK
LAEMVIEAVPSVEMVRFVNSGTEACMAVLRLMRAFTGRDKLIKFEGCYHG
HADMFLVKAGSGVATLGLPDSPGVPRSTTSNTLTAPYNDLEAVKNLFAEN
PDAIAGVILEPIVGNAGFIQPEPGFLEGLRELTKENGSLLVFDEVMTGFR
ISYGGAQGRFGVTPDLTTMGKVIGGGLPVGAYGGRKDIMSMVAPAGPMYQ
AGTLSGNPLAMTAGIKTLEILQQEGTYERLASITNRLINGICESAKQAGI
PITGSSISGMFGFYLCEGPVRNFEEAKQTNSDYFGKLHRAMLAKGVYLAP
SAFEAGFTSLAHSEEDIDSTLKAFNECFNELSQ
>Pro1385 hemN, Oxygen independent coproporphyrinogen III oxidase
MNYPRSAYLHIPFCHRRCFYCDFPVVPLGDRAGTENGPGSSSVKSYLNLL
HREISLAPKVASLSTVYIGGGTPSILSADQVANLLDHLRLHFGFQNGAEI
SFEVDPASFDTFSLEGFLDAGVNRLSLGAQSFDDKVLAQLGRRHTANDLL
DACGWINQAFNERKLFSWSLDLIQNLPGQDLCSWEKQLLKALDISPPHMS
IYDLSIEKGTVFEWRQNRGELSLPNEDDASDMSKMTSDKLKQAGFSRYEI
SNYALPGHASRHNRVYWSGSGWWGFGQGATSCPWGVRSSRPRTREKYKKW
LEVQENDGLDKSLTLNNEGQLIPLDELLIFGLRRREGIDFKELVSSFNWD
ESQLEINLNNLKNYWANSLKEGLIKQRGYRFYLTDPHGMDLSNQILVDML
LWYESLLNSSIDQPNL
>Pro0526 ilvB, Acetolactate synthase
MTLSSSPFGIGDSTKKEQNQILGADALMESLKNHGVDTIFGYPGGAILPI
YDAVYKAEKAGWVKHILVRHEQGGAHAADGYARSTGKVGVCFGTSGPGAT
NLVTGIATAQMDSVPLVVITGQVPRPAIGTDAFQETDIFGITLPIVKHSW
VVRDPSEIASVIAQAFFIASSGRPGPVLVDIPKDVGQELFDYQPVQPGSL
IPAGFTPPQKPDPVAISKALDLIERAKKPLLYVGGGVISASAHDTLFAIA
KRYHLPVTTTLMGKGAFDERESLSVGMLGMHGTAYANFAVTECDLLVAIG
ARFDDRVTGRLDSFAANAKVVHFEVDPAEINKNRVADVAVLGDLAISLSD
LHELSKRRTVKPNTQEWLAQIEEWKIKYPLLIPSKEGEIYPQEVLIEIRD
LAPDAYITTDVGQHQMWAAQYLRNSPRHWISSAGLGTMGFGVPAALGVQV
ALPKQQVICIAGDASILMNIQELGTISQYQLNTKIIIINNHWQGMVRQWQ
QSFYDERYSATNMLNGEPNFVALANAFGVGGVIIKERNSLKEKLKEALNS
EGPMLIDVHVRRDENCYPMVPPGKSNAEMVGLPD
>Pro1389 ilvC, Ketol-acid reductoisomerase
MAKLFYDSDADLQLLSQKTVAIIGYGSQGHAHALNLKDSGIDVVVGLYEG
SRSASKASSDGLEVMSVADASAKADWIMILVPDEFQRDIYAKEVAPHLKP
GKILSFAHGFNIRFGLIEPPSFVDVVMIAPKGPGHTVRWEFQNGQGVPAL
FAIEQDASGQARSLAMAYAKGIGGTRAGILETNFKEETETDLFGEQAVLC
GGLSALVKAGFETLVEAGYQPELAYFECLHEVKLIVDLMVKGGLTAMRDS
ISNTAEYGDYVSGPRLINADTKKEMKKILADIQDGTFAKNFVAECEAGKP
EMKRIREEDSLLPIEKVGKGLRAMFSWLKTD
>Pro0958 ilvE, Branched-chain amino acid aminotransferase
MHDFLPYAWFKGKCVPFDEAKISIATHALHYGTAAFGGMRAIPDPSDNGN
FLLFRADKHAKRLSQSAKLLLTELSERYILQSIETWLKANKPSKPIYIRP
FVYTSDLGIAPRLHNIETDFFIYGLELGDYLSPEGVSCRISSWKRQEDCS
LPLRGKISGAYITSSLAKTEAVLTGFDEALLLNSQGKVSEASGMNLFIVR
DGNLITPGTDQDILEGITRASVIEIANYLGINVIERPVDKTELFIADEVF
LTGTAAKITPIKQIESTLLNTELPIMNKLRDYLISITENKEDKFSNWITS
IKIS
>Pro1129 ispA, Geranylgeranyl pyrophosphate synthase
MAEAVMFPFDFTAYLAKARTRIESALDASLGPERPNQLREAMRYSLLAGG
KRLRPILCLAACELTGSDSENAISTAVAIEMIHTMSLIHDDLPSMDNDDL
RRGRPTNHKVYGEAIAILAGDALLTRAFEMVALRSPNVPKDRLLKVVGEL
SLVAGAPGLVGGQVEDLESEGKAVDLDTLEFIHIHKTGALLKASVVCGAL
IGGADEDLLIALSTYAKGIGLAFQIVDDILDVTASSEVLGKTAGKDLLAD
KSTYPKLLGLDESRKKAKELIRKSKDVIHPWSDKAAPLLSLADYIINRDR
>Pro1099 lipA, Lipoate synthase
MTTTNKKTRYSAIKPSERLPEWIKPSLGTASQLEKVQNLVKEYRLNTICE
EGRCPNRGECYASGTATFLLGGSICTRSCAFCQVEKGMPPQNIDPNESIR
VAKAVLKLQLKYVVLTSVARDDLDDHGAIHFSRTIHAIRKTSPTTSIEVL
TPDFWGGCIDKIKATKIQRERLKIVLKAKPVCFNHNLETVERLQKEVRRG
ATYHRSLELLKASREIDNEIPTKSGLMLGLGERSDEIIQTLKDLRSVNCQ
QVTIGQYLRPSLAHIPVQKYWLPKDFEHFKRIAEGLGFKKVNSGPLVRSS
YHAELPQT
>Pro1670 lipA, Lipoate synthase
MASMNTHKPDWLRVKAPQHERIGYVADLLSDLNLNTVCQEASCPNIGECF
AGGTATFLIMGPGCTRACPYCDIDFDKSVRSLDPSEPERLGEAVKRLGLK
HVVITSVNRDDLEDGGASQFVSCIDAVRASSVETTIELLIPDFCGNWDAF
KKVMNASPNVLNHNIETVPRLYKRARPQGLYKRSLELLRRVRQESPNVYS
KSGLMVGLGETDDEVLQVLSDLHDNNVDIVTIGQYLSPGTKHLPVDRFVT
PDQFQKYKEEGQTRFGFLQVVSSPLTRSSYHAGEVKRLMQIYPR
>Pro0398 lipB, Lipoate-protein ligase B
MHNLVINDLPEEGLPTALFEPSELIDFKIAWDWQRKWQEKLLAEPSNKQA
VWMLEHFDCYTLGRGASEDNLLFDVEKPPIDFYRIDRGGDVTHHLPGQLV
VYLVLDLRRYKTDLDWYLRQLENVLLDVLDGLGLNGYRINGMTGVWCNGK
KVASIGISCRRWITQHGIALNVDCDLLGFNQIVPCGLKDYQTGRLNSWLP
KLQMKEVRFLMKKSLNKRFGLLWI
>Pro0540 lplA, Lipoate-protein ligase A
MFNEKYSYSSKKRKCHGQIIHSSALSGPCQMAADVMMLEKLLQIPEISLL
IRFYQWEGTWLSIGKNQRELPRHWINLIKERKLNIVRRPSGGTAVLHTGL
TYSLAWLSPPIKKHQAYIAASQWLINCFSKLGLHLQFGNHPHSFISDNCF
STSSSADLVDQNGIKRIGSAQFWKRGNLLQHGEILLDPPKELWEEIFNTD
PPKPAPKTVPRVDLERLLTEALISHWSTLKWSHKGLEPNDLKEISENSNS
YLVTLSNSDFGINPESIIPSTILNKEIPKG
>Pro0201 menA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase
MKDKNAVASLHSSSIPRKKLWKKAIKWPLYSVAIMPVILAAGWKQGAGEI
IRLDQLVGFLIASILLLIWENLTNDLFDSTTGVDEFKLHSIVVLTGRRRL
IRNLAYFILFLGLILILILASRSHQAVFFLVIGSCALGYLYQGPPFRLGY
QGLGEPLCWLAFGPLATAASLLVLSTNVNHTNPIPWKAAISLGAGPAVAT
TLVLFCANFHQVSEDAAHGKKTLLVRLGTGRAAAIVPWFILLCLGLEWIP
IVYGQWPVTALLGGIGIPPAIKLIRLLTDHHNHPKLISESKFLALRFQAL
NGIGLSIGLALAPFLGIELQH
>Pro1053 menB, Dihydroxynaphthoic acid synthase
MDPIRSSRRVLPGDITVNWKTWGKYEDIFLDRSEEGIARVAINRPERRNA
FRPLTVSELCDAFIKIRDDTSIGVVLFTGVSPAKDGVFSFCAGGDQSVRG
EGGYLDEEGLPRLNVLDLQRLIRSIPKVVIALVSGYAIGGGQVLHLLCDL
SLAADNAVFGQTGPRVGSFDAGFGAGYLARVVGQRKAREIWFLCRKYGAQ
EALHFGLINSITPVEQLEAEGVKWAKEILENSPTAIRCMKAAFNAETDGL
AGIQELAGQATHLFYRTTEAKEGKNAFLQKRKPDFSDFDWLP
>Pro1054 menD, 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase
MRAFQRYGLEHIVLCPGSRSAPLALAVGALIEESGINAYTAIDERSAAFM
AIGISAASGKATIVITTSGTAVSNLLPAAVEADRSCLPIIFITADRPLRL
KGCGSNQTVNQEDFLVPVCREVFNCPSIGLHEISGRSFFTLVKKTWEKAH
AYPGPVHLNIPIEEPLHASFLEQKEVCNGWKPLNFEEIQLPISTVSTNTR
IKTKEVPELDPSQPGIILAGPWRGKPSQLLGFRKAVKEFQSFTGWPLFAD
CLSAITIKQSGLISFWELLISAQIFESNDKLQVLRLGPLSCSRALESFLR
NTNKKQVLITEGEERYLDPLHLAKQYSGGLQSWLKIFKSNYPNLNNNLVN
DDTNILEDLLNKNQLVGDLVDKYLKEDSKITEPSIARKLLDLIPEDIPIM
LSASSPVRDFLAYSGFSPFKRRLYSFRGASGIDGNLSLAIGLSIFLGPLV
VVCGDLAFLHDSNALLLNQPKKYPLIILLIDNNGGGIFKQLSLAPIFKGS
VDKLFSMPQSINIGDLAKAHNIPFRTISSFDELNSALEWSLKLSGPVIIR
ACTNSEEDTLLRKNITDGLKKYIN
>Pro0202 menF, Isochorismate synthase
MKANLTFSEILQASLRGWNSRRADECVLSLALPIDTIDPLKQLSVIADQQ
EFSFLWDQSPGLSIAAAGRCQNLELIGQRRFELAQRFSDETLGRIVDISV
SAPKQAKPRILFAFTFFEQISDEKRFVKTTPAVQAVLPRWQLSRQAGVSW
LRFNSVVAHEADVRRFVEECWLMRENVNKPLLTELSSKTNIGFAKSPSQE
WQNSYRLTLEKGIELVNTGELQKLVLAVRQSFLLSEPLDPLGMLESLRRY
QRGSCRFLWKRSEDESFFGASPERLLSINKENLQTDALAGTAGADENGLD
LLKSEKNLREHELVVSSIQNQLINKGLDPSRIRSPRLARHGHLIHLHTPI
KSSCKGFSPLQLVEILHPTPAVAGLPRNKSIQWLRTLEPFDREGYAAPIG
WVDSSGDAEFRVAIRCAYTRGNNLHLMAGAGLVKGSTIEGELQEVGLKFA
VLANQLDLNFESQEKFARRRSIT
>Pro0349 metK, S-adenosylmethionine synthetase
MPSFVFTSESVTEGHPDKICDQVSDAILDALLDQDPNSRVACETVVNTGL
CLITGEVTSKAKVDFINLVREVIKEIGYFGAKAGGFDSNSCSVLVALDQQ
SPDIAQGVDEADDHSGNPFDQVGAGDQGIMFGFACDETPELMPLPISLAH
RLSRRLAKVRHDGTLKYLLPDGKTQVSVLYENNKPTAIDTILISTQHTAE
VEGITSEKGIREQISKDLWELVVKPATEDLPIKPIQEKTRFLVNPTGKFV
VGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSAAYAARFV
AKSLVAAGLASRVEVQLSYAIGVANPVSILVEAFGSGKMSNEALTELVTE
NFDLRPGAIIEQFGLRSLPNQRQGRFYRDVAAYGHFGRPDLNLPWEDVQD
KAKELIESQK
>Pro1013 nadA, Quinolinate synthase
MTEGNWIRTSILPQIAKKKLSTVYSTQQTVLPDPLTRDEVKNQIRLLCKE
KNAVILAHYYQDDLIQDIAHFIGDSLELSRKAAETEAEVILFCGVHFMAE
TAKIICPDKKVIIPDMDAGCSLADECPEEDFKKFINKYPDHYVISYINCS
AAVKAQSDLICTSSNAVDLVKRIPLNIPIIFAPDKNLGRWVEKQSGRKMK
LWQGSCMVHETFSEESVIKLKLQHPKAEIIAHPECTDQLLDYSDFIGSTS
KLLSHVQISPAEEFIVLTEPGIIHQMRIKEPKKKFFEVLGLDGCSCNSCP
YMRLNTAEKVIKSLKELTPEIILDEEVQNKALRPIKKMLSLSK
>Pro0119 nadB, Aspartate oxidase
MNSARITSNSWDVIVVGAGAAGLMTCIELPPHLKILLLNRNTSKRSASRW
AQGGIAAVTREEDSLQSHADDTFRAGCGLCDTDAVKMLVEHAPQCVERLQ
KLGMEFDRDSKGLATTLEAAHSHRRVLHVQDRTGRALVDVLREQVEKRSN
IVHCRGVRVTQLLVEHNCCDGVQVLDGPLLYWIQSKAVVLASGGGGHLFA
NTTNPAQACGEGLALAWKAGAAIEDLEFFQFHPTALKLQGATSFLISEAV
RGEGAVLVDRDGNSPVAHLLRKDLAPRDQVSRALVKTMQSQGVSHIGLDL
MNIPPEKIFARFPSIIQRCREMGIDPLNNLIPVAPAAHYWMGGVATDMQA
ATSVSGLYAVGEVACTGVHGANRLASNSLLECLVFASQMSVINVTESSRK
NIISNQTFLTKLSNNLDCEQSENDLQSSIEDLRKLFWKEVGVNRSKKGMQ
DALNNIRLDLDSLNKNALLELVSNQSIDICNSFDEGTRRKLNLLLDLNHR
KLTCLLTLNACLFRTESRGGHYRLDSPATLPYWRCHSRQKKGQTISTRPV
RE
>Pro0213 nadC, Nicotinate-nucleotide pyrophosphorylase
MNIITPNIHHLLDTWLNEDLGRGDLSQSAVENYRAHAHWVSKQEGIFCGG
EIVKCLFQRLDPSIEITLQKGEGAKLMVGEKIMDLNGPVASLLAGERTAL
NLAMHLSGVATATKRLVSKLQGTGILLADTRKTTPGLRQLEKYAVRCGGG
INHRLGLDDAAMLKENHIAWSHGIKQSIHTLRSNIPWTTKIIVEAETTQE
AKEAVSAGADGILLDEMSPNEITNLIPQLRELAKQNSKELIIEASGIDPN
KILDFASTGVDIISTSSPITQSTWIDFSMRFNKQEVN
>Pro1598 nadD, Nicotinic acid mononucleotide adenylyltransferase
MKNNSYSSIALLGTSADPPTIGHKILLTELSKIFPKVVTWASDNPSKSHK
TSLNQRYELLNTLVEAIALPNLELKQELSSKWAIKTLERAAKHWPNKGLI
LIIGSDLVTDIPHWFEAKNVLQHAQLGIVPREGWPIGNSNLEKIKEMGGT
PILLPLKIPETASSTIHNHLLFSQIPKALLPILKKKNLYGLSQKM
>Pro0209 pabA, Anthranilate/para-aminobenzoate synthase component II
MLLVIDNYDSFTFNLVQYFGELASKHSIAKNILVERNDAISISQIKDLDP
QAIVLSPGPGNPDQSGVCLEVLSEFAGIKPILGVCLGHQAIAQTFGGKIV
RAKELMHGKTSKVFHTGDHLFAGIPVPLVATRYHSLIADRESLPQCLEIT
AWLKDGTIMGLRHKQFSHLYGVQFHPESVLTEAGHHLLSNFLGLAESSKN
>Pro1384 panB, Ketopantoate hydroxymethyltransferase
MLPKELVRFKELGNQITILTAWDSLSSAIVEAAGADVVLVGDSLAMFIHG
HTTTLPVTLEQMLHHTQAVGRGFLSPKNKQPLVVCDLPFLSYQCGEDKAV
AAAGTLLKNSCAAAVKIEGAEPEVISVIERLIRMGIPVMGHLGLTPQSVN
NLGYHRQAEDALGQEKLVTQALKIEQVGCFSVVLEHVPSKVASKVTQMLK
IPVIGIGAGEECDGQVRVTADLLGLTDKQPPFAKPLIDGRSLFIESLTSW
VDQLRN
>Pro0028 pdxA, Pyridoxal phosphate biosynthesis protein
MKKRNQYFEARNRVVIALGDPAGIGTEITLKALGSLLLPKNMQPLLVGCK
RNAELTYYNLKTKGIKSLANPKDLEFEDIPFKEHVIAGQPSQKTGKASFN
WLTRANEIVLKNEARALVTAPIAKHTWHAAGHNYPGQTERLAELTSTKNP
SMLFTAKSPFTSWRLNTLLATTHIPLAEVPRNLSPELIISKLDTLLNFCQ
KFNNEPKLAIAGLNPHAGEKGQLGNEEIQWLNPVIEEWRVNNPNVILEGP
ISPDTCWISTAQSWKDTHLTKGPDGILALYHDQGLIPVKIIAFDYAVNTT
LGLPFIRTSPDHGTGFDIAGKGIANSKSMFSAIETAWELSDV
>Pro1089 pdxJ, Pyridoxal phosphate biosynthesis protein
MTSLGVNIDHIANIRQARLANEPDPVQMALLAELGGADGITIHLREDRRH
IQDRDLKLLRETIKSRLNLEMAATTEMIEIALDLKPDMITLVPERREEIT
TEGGLDVASNAKSLKEIVTKMESCCIPTSLFVDANSKQLEASSKIGATWV
ELHTGPYARASWKNQPLEFAKISEGVARARNLGLRVNAGHGLTYQNVEPI
ASITEMEELNIGHTIIARAIAIGLKEAVKEMKELIKNPRHEPFFGS
>Pro0943 ribB, 3,4-dihydroxy-2-butanone 4-phosphate synthase
MTATNSLNIAFDQIADALAAIRNGECVVVVDDESRENEGDLICAAQFATP
QQINFMATEARGLICLAMDGERLDQLDLPLMVDRNTDSNQTAFTVSIDAG
PEYGVSTGISAEDRARTIQVAINPQTKPNRLRRPGHVFPLRANKGGVLKR
AGHTEAAVDLSLLSGLSAAGVICEIQNADGSMARLPELTKYAKTWGLKII
SIADLIRFRLENERFVYRKAKTRLPSIFGDFQAIGYTNELDGTEHIALVK
GNINELKEPVLVRMHSECLTGDAFGSLRCDCRPQLEAALNLISEEGEGVV
VYLRQEGRGIGLINKLKAYSLQDGGLDTVEANLKLGFAADLRNYGVGAQI
LTDLGINRLRLLTNNPRKIAGLGGYGLRVESREPLVINPTDYNANYLAIK
RTKLGHYIGNDDDSGKYYVIYWKGIVSSNMLSAYKNKAEQIASDNKVELN
PESSSRLLALLQRPQFVWRVQNCIDFESIINLLKEIIKWDGTKSIGIFIT
NSKEQAIHPSQDVETILENISNLKDTNYKNIANINDKDLPFIMTWQ
>Pro0438 ribC, Riboflavin synthase alpha chain
MFTGLVQAVGTIHRAGKKVLVEVPTSFPSIALGDSIAVDGVCLTVAALRN
KGFFADVSEETLARTSLGEKATERGFVNLEPALRISDRLGGHFVSGHIDG
LGKVVSIKELTSSWDLQIRWQENIFAKYTCDKASIALNGVSLTIAKRKEG
NILSIAVIPHTWANTSLQYLLEGEFVNLEADLIAKYTESLLEQRSDMADK
SNQLKTKPLEISDNWLKANGYS
>Pro1339 ribD, Pyrimidine reductase
MATNLNSHIWEPWMFRAINLASLAEGQTSPNPLVGAVILDEKNRLVGEGF
HLRSGEPHAEIGAIEQAGSLAKGGTLLVNLEPCCHRGKTPPCTDAILRSG
IKRVVVAIQDPDQRVSGKGIAFLKESGIEVVTGILEKEAAFLNRAFIFRN
RTGRPWGTLKWAMSFDGRIGLSNGKSKWISGEKSRKRVHSLRAKNDAVIV
GGGTVRSDNPLLTTRGIADIEPLRVVCSSTLDLPKEAQLWNTELAKTLIF
YGPESDARCLENLPSGPERLCLEENTPIKVMEALAQRGCNQVLWECGSSL
ATKAIQQNCVQELSLFLSPKLLGGVSAMTPLADFGFSSMEQVFKLKEVSS
NKSGEDFVLNMLFDNYG
>Pro0126 ribD, Pyrimidine reductase
MSLPWIRLVLAISLDGRLAPSNGGKANLGGEGDRRVLEEALAWSDATLMG
SGTLKIHKNTCLIHDSKLIRERHTQGRSTQPISLIISKQSSFPQTWQFFR
QPITRWLLIPKAKTQIFTSEGFEQQIVMQDNWSGTLHDLNQKGCSRIVLL
GGIQLITSLLLEDKVDELQLTFTPRLLGGKYTWTASGKNSLPIELTKSDA
WHLKGIEELGKNEVMIKYLRKRS
>Pro1347 ribF, FAD synthase
MISLCSPLQARLPTALALGSFDGLHAGHRSVIKTITSNTTAVPTVVSFWP
HPREVLYGESKLRLYLPSEKALLLEHLGVKQLVLVPFDLSLASLSADEFF
HEILIKNLQAKQISVGANFRFGKNREGDSDKLIELGEKANIKVRVLEIIE
DNQGRMSSSRIREALKDGDIKLTNSLLGRAYSFGGKVVPGKGIGRKLGWP
TANLEIDGSKLLPGQGVYAVMTRASDEKSFSPAIMNLGPQPTINPHAPSA
TEVHVLNKQVNLKGKDLIVEPVERIRTQKKFTTLKDLSNQIELDARKAIS
ILTQR
>Pro1803 ribH, Riboflavin synthase beta-chain
MVSIEGRFTEASSLKIGIVAARFNDLITSKLLSGCIDCLTRHGIDTSESS
SQLDIAWVPGSFELPLVSQTMAKSGRYQVLITLGAVIRGDTPHFEVVINE
SSKGIASVSRETGVPIIFGVLTTDTMQQALERAGVKNNLGWNYALQAIEM
GSLMKALK
>Pro0203 rimK, Glutathione synthase/Ribosomal protein S6 modification enzyme
MKQLFILDPIELINPAKDSSAALMQAAHRASLDIWVCTPADLQAKGAKAR
VVAKTIVPEPWKSLGEAQNLSLNEFHCIWMRKDPPVDEAFLYATHLLEVA
ERAGVLVLNKPASLRAWNEKLGALRFSKLMAPTLVASRVNELKEFAKEQG
EVVLKPLGGKGGQGVIRVADAALGLDALLELVTSQEQMPVMMQKFLPKVI
EGDKRILLVNGEPLGAINRLPKCGDFRSNLALGGQAEATNLSKREKEICE
ELGPSLKSEGLFFVGIDVIGGMLSEINVTSPTGVREVEKLMNIPLADQVI
ERLLANFS
>Pro1436 serA, D-3-phosphoglycerate dehydrogenase
MTKVLVSDPIDHAGIDILSQVSQVDQRLGLSSNQLKEIIGDYEALMIRSG
TQVNSEIIEAGVNLKIIGRAGVGVDNVDVPAATKRGVIVVNSPGGNTIAA
AEHALALLLSLSRNIPQAHLSTISGKWDRKKFVGNELYKKILGVVGLGKI
GSHVAKVANAMGMDVMAFDPFVSAERALQMQVRLSSIDDLFKEADFITLH
LPRTSETENLVDAKLLSSMKQNARLVNCARGGIIDETALAEALNSNVIGG
AALDVYSQEPLKNDSPLLNVKNNLILTPHLGASTAEAQQNVAIDVAEQIR
DVLLGLPARSAVNIPGLSAEIMDSLKPHLQLAESLGLLASQVSGGQIQKI
EVKLQGEFSQHPSQPLVIATLKGLLSSALGNRINYVNASLEAQGRGISVE
EVKDEASPDFPGGSLQLRTFADKGTNSVTGTVLADGELRISSIDEFPINV
SPSRYMLFTRHRDMPGIIGKLGSLLGTHNVNIAAMQVGRRIVRGEAVMVL
SIDDPIPSELLTSILAVEGINQAHAVTF
>Pro1771 thiC, Thiamine biosynthesis protein ThiC
MIMRTSWVASRKGQSNVSQMYFARREVITEEMSFVAKKENLPESLIMEEV
ARGRMIIPANINHLNLEPMAIGIASSCKVNANIGASPNASDVNEELKKLH
LAVKYGADTVMDLSTGGVNLDEVRTAIIQASPVPIGTVPVYQALESVHGS
IEKLSEEDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRLTGIVSRGG
GILAQWMLYHHKQNPLFTRFDDICEIFKRYDCSFSLGDSLRPGCLHDASD
EAQLAELKTLGELTQRAWKHDVQVMVEGPGHVPMDQIEFNVRKQMEDCLE
APFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPN
PEDVREGLIAYKIAAHAADIARHRSGARDRDDELSRARYAFDWNKQFELS
LDPERAREYHDETLPADIYKQAEFCSMCGPKHCPMQTKITDKDLENLESI
LSSKGAKEINTMKLDKEV
>Pro1348 thiE, Thiamine monophosphate synthase
MSVTPNPDQHVAQLIDANLDRAREGLRVIEDWCRFSLKNKDMVITLKNWR
QQLGKEHYEIYKNARSSSSDQSAGLSHPAQKERILPQQILSANFARIQEA
LRVIEEFSRISHPKLSKISAQIRYEIYDLEVIILKISNLNMLDEKLKSCK
LCLITRTHPELIKTVLLALKAGVTMIQYRCKETPDNQMIAEAKELASICK
SYNSLFLINDRADIALAVDADGVHLGQKDMPIQTARKIIGHQKIIGLSTH
SLEEIQNATSQGCNYIGIGPIFKTKSKQNDLSLGIDFFSKINLKTNLPWF
AIGGINKDNIDKIKEVGIKRVAVINAIMGAEDPYLASKELLGKLKK
>Pro1824 thiG, Uncharacterized thiazole biosynthesis enzyme
MNNNSSSLSIGNKLFKSRLLIGTGKYQTLNQMQESIINSECEIVTVAVRR
VQSSESSHKGLMEAIDWKKLWMLPNTAGCTNSEEAIRIAKMGRELAKLSG
QEDNNFVKLEVIPDNRYLLPDPFGTLEAAEALIKEGFVVMPYINADPLLA
KRLENIGCSCVMPLGSAIGSAQGIRNESNIRIIIENSNVPVIVDAGIGVP
SHAAEAMEMGADAVLINSAIALAKDPKSMAEGMCKGVHAGRKAFLAGRLV
EQPLANPSSPCTEISKSSYVQ
>Pro0024 thiL, Thiamine monophosphate kinase
MLKEENTQEILHDLGEQEILNRLRKYMDYGQIDDDTALIKSYKKELIINT
DMLVEDVHFSEITTNPNHIGWKAVATNLSDLACSGLEEVIGITVGLSAPS
STPWSWVDGVYTGIKAALNKFGGKLLGGDCSNGKQKTLCITALGTKGPLN
LHRSNARPGDYLITSGPHGLSRLGLSLLLSDPITKSINVPNLLKEHAIKA
HQEPQPPIKALQTLLKCKPYAMPWNAAATDSSDGLLEAIESLCRSSNCTA
VVDHKNLPKHADWPSGKQWNDWCLEGGEDFELVVSLPPNWAKAWLKAMPC
TKAIGRMKEGPAKAMWSNGETIQKAMDTKFEHF
>Pro1349 thiS, Sulfur transfer protein
MNLIINGEQKIINANSQVANLAIVIKELGFNPKLIVVEFNGLILSPQVWE
TQEVRDGDILEIVTIVGGGC
>Pro1856 trpE, Anthranilate/para-aminobenzoate synthase component I
MNNLCRELLDWVDPQIVAQKLIQIYGEPGLVWLDSDGSKNGRWIILGADP
IEHICSHGLPNDPSATNPFELLRTIHSGHWSGWLSYEAGAWIEPNNPWKQ
DSMATLWCARHDPILKFDLYNQQLWLEGIDRKRLVEIRELLKELKASNLQ
KNQSLKRTKEFQGIAKEKWKWLNNKEEYAKKVATIKQYIEEGDIFQANLS
TCCQTKNTANLLSIDLFKRLRQYCPSPFSGIVVATGEALGEAVISTSPER
FLKVLPNQKVETRPIKGTRPRHANPKKDSEFAADLVSSLKDRAENIMIVD
LLRNDLGKVCIPGTIDITQLVGLESFSKVHHLTSVIKGKLKTNKTWVDLL
EACWPGGSITGAPKIRACKRLYEQESIARGPYCGSFIHLDWNGQFDSNIL
IRSLMVQKSSLRIYAGCGIVADSDPYSESEELTWKIMPILEALQ
>Pro1732 trpE, Anthranilate/para-aminobenzoate synthase component I
MSISDRVSFLDAASRGINFIPLVQTWPADLETPLSTWLKIGQKNPPGVLL
ESVEGGDTLGRWSVVASNPLWVVTIKGEKITRTWRNNEKEEFVGNPFELL
RKCLAPYKSQLIPGLPSLGQLYGMWGYELIKWIEPKVPVYSQNDEQFPDG
IWMFMDKILIFDQVKRLITAVSYGDLTSADSPEDAYEKAFQGIKEFESLM
QEPLPSIKSLKWNQKPSIPDSIESNWSKSEFEHAVEEAKEYISKGDIFQL
VLSQKFTTQVPHSPLELYRSLRIVNPSPFMAFYDFGDWQLIGSSPEVMVQ
AKPIDKKVSASLRPIAGTRPRGKTANEDSELEAQLLADPKEIAEHVMLVD
LGRNDLGRVCRAGSVSVNELMIIEKYSHVMHIVSELQGYLKDDMDVWDLL
MAAFPAGTVSGAPKIRAMQLIHELEPHIRGPYSGVYGSMDLNGALNTAIT
IRTMLVSHHSKDLFNVEVQAGAGIVADSIPQNEFQETLNKAKGMLIALGC
LEPSI
>Pro0455 ubiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases
MKSFLLTKKLLNIFHLLRWNKPTGRLILLIPAGWSLWLTPNAPPSKELVT
LIIAGAISVSGAGCIANDLWDRKIDSKVKRTKNRPLANGSLSIVEAFSLL
IFLLIISLKVILLLPTPSQNLSLKLAAMALVPILIYPSSKRWFRYPQVLL
AFCWGFAVLIPWAASEHSLNGGFPLLTCWLATMVWTFGFDTVYAMADKDD
DKKLGLQSSALSLGQKALKSVFICYALTSTLIAFSALTKDIGIIFWPFWL
IASIGMQKEVFSLKELEANTNKFGKHFRNQVFLGGLILFGLILGNF
>Pro1047 ubiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase elated enzyme
MNVFQNGVGSQDMRDFLSLLEKKGQLRRISKPVDPDLELAAISDRVLSMG
GPALLFENVIGSSMPVAINLLGTIERVVWSMGLSSQDELEGLGKKLSYLQ
QPEPPKGIKKTIEFGGILWDLLQARPDLDLTPPCHQRLLKGEDVNLDKLP
LIRPWPGDAGKIITFGLVITKDPETNTPNVGVYRLQQQSINTMTVHWLSV
RGGARHLRKASAMGKKLEVAIAIGVHPLILMAAATPIPVTLSEWLFAGLY
AGKGVRLSNCKTVNLQVPSHSEIVLEGTIAPGEEMNDGPFGDHMGFYGGI
EKSPLIRFHCITSRKDPIYLTTFSGRPPKEEAMLAIALNRIYTPILRRQI
NEITDFFLPMEALSYKLAIISIDKSYPGQARRAAMAFWSALPQFTYTKFV
VVVDSTINVRDPRQVVWAISSLVDPQRDLLVMENTPFDSLDFASENIGLG
GRLAIDATTKVGPEKNHEWGNPLIHSSNLSKKIDERWNELGLSDLKPNHA
DPSLFGYVIDEIIKFNQITKS
>Pro0427 ubiE/menG, Methylase
MKPQDPIAIKELFDSVSKNYDFLNDLFSLGFHRIWKRQLLTWLKPASGEK
WIDLCCGTGDLSLPLARLVRPFGSVIGVDFSRAQINCAHKRSLKEPWLPI
SWLNEDVLKAGLPSSTFDGVVMAYGLRNLSSPEAGLKEIHRLLKPGARAG
VLDFNHTIEGSKNSFFQKFYLRNFVVPIASKMGLKEEYAYLEESLKKFPV
GLIQEQIAINVGFQEANYKTLAGGQMGALLLRA
>Pro0906 ubiH, 2-polyprenyl-6-methoxyphenol hydroxylase related enzyme
MSNLHIKVIGAGPSGSLLALSLVGNSNAVSIYEAKSKEQILLRDRTYAIN
HSSRRLLQRIGIWDDLNEFMIPFDSLSLEDYSVNQRLVLYNKDLVNLNSS
YKEVGWTLDHKLLMEYLFYKISKSSNINIKFSSKDNDANALYDYTFAADG
TNSRYRDLWKFKSYRFKYNQECITFKALLRTPFTHRAYEIFRKDGPMAIL
PMANDLYQIVLSMPPLKSDYLLNLTTSHFLDTVATYLPIGMEIDTLINKP
QKFSLSLNVPIKLQDYNRFLIGESLHSLHPVGGQGLNLSIRDIDDIMNLL
TSSNLLQYKICRYIDIYTTSFLTHMLIVIFSSNNIILKVFKLSLFTILRK
SILFRKIVLSLMTDGIPHIFK
>Pro0989 ubiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase
MSSIVLAITGASAQILAERSIDLLLRCNQKLDVIISKGAYEVWKSEMNVN
IPAEGAKQATFWRNRLKNNQGEIICHKWNDNSATIASGSFRTKGMVIVPC
SMGTIGRIASGSSINLIERCADVHLKEGRPLIISPRESPFNLIHLRNMTT
LCEAGAKIIPCIPAWYSKPKDLEEVIDFMVVRLYDLFDLNMKDINRWKGN