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# Vibrio vulnificus CMCP6, CMCP6

>VV10961 Sulfur transfer protein involved in thiamine biosynthesis
MNTIAISINGESYEVPTNATLASIIEHLSLPNLGCVFAINNQVVPHSEWQ
TKTLSRGDAISLFQAIAGG
>VV20454 Pterin-4a-carbinolamine dehydratase
MLDELKCEACSIDAIALTTQQQQELLLELEGWHLMEREGIPQLEKVYKFK
NFMQAWQFSNQVAELAEQEFHHPSILLEWGKVTVTWWSHSIKGLHKNDFI
CAAKCDQIIR
>VV11032 Aetolactate synthase II, large subunit
MTGAELVVAALKQQGIKTVFGYPGGAIMPIYDALYDGGVEHILCRHEQGA
AMAAIGMARATQDVAVCMATSGPGATNLVTGLADAFLDSVPLVAITGQVA
SSHIGTDAFQEMDVIGMSLSCTKHSYLVTDINELAPTLAEAFEVAKTGRP
GPVIVDIAKDVQLAKAPVELLPPFTPPALPQVSQVDVARAQTLLDQSTRP
VLYVGGGVQLAKATHTVREFLRLNPMPAVSTLKGLGTIERHDPHYLGMLG
MHGTKAANLVVQEADLLLVVGARFDDRVTGKLETFAPHAKVIHIDIDAAE
INKLRHANAPLRGDINVILPQLELTRDISPWVHHCESLRSGFKWRYDHPG
ELIYAPGLLKQLSDLMPDNTIVSTDVGQHQMWAAQHIQPREPQNFITSAG
LGTMGFGLPAAMGAAVARPDAQSVLISGDGSIMMNIQELGTLKRRQIPVK
IVLLNNQRLGMVRQWQSLFFDGRHSETILDDNPDFVMLAKAFDIPGKTIT
KKEEVEPALKEMLASKTSYLLHVLIDEEENVWPLVPPGASNSDMLENT
>VV11606 Gamma-glutamylcysteine synthetase
MNFILTDFAARLELVARNPEVFKQFGRGVERETLRYSQNGRIATTMHPQG
LGSAFTNQWITTDFAESLLEFITPVSHDIDVLLGQLDDIHHFTQTQLGEE
KMWPMSMPCYVETEDQITLAQYGSSNSAKMKTLYREGLKRRYGSLMQIIS
GVHFNFSFPESFWDALHGEQTEDERQATKSEAYFGLIRNYYRFGWLIPYF
FGASPAMCSSFLQGRETSLPFEALGKTLYLPKATSLRLSDLGYTNSAQSV
LTIGFNSIDEYLEGLTKAIRTPSAEFAKLGVKENGEYRQLNSNVLQIENE
LYAPIRPKRVAKNGEKPSEALARGGVEYIEVRSLDVNPFTPVGITETQVR
FLDLFLTWAALSESQPMDQCELACWRENWNKVVVSGREYGLELQIGCKGE
KLSLQAWAHRVFAELRQLAEVMDSAHGDNQYSLACSELEQWIDHPEKTLS
AQLLTLIQQNGSLGATGCELGGAYREQNLAHHYRHFSLQQMEQEVALSLI
KQSQIEQADEVDFDTYLADYFAYLK
>VV10933 NAD(P)H-flavin reductase
MTIQCKVKSIKPLASNTYQILLHPEKPVSFKAGQYLMVVMGEKDKRPFSI
ASSPCRHEGELELHIGAAEHNAYALEVVEVMQNALDNDSYIDIDAPHGDA
WIREESERPMLLIAGGTGFSYVRSILDHCIAQNKPNSIYLYWGARDYSQL
YASEELALIASQNANVHFISVVEESPANWQGKVGNVLQAIHEDFSSLENY
DIYIAGRFEMAGLAREQFTQQKQAKRERMFADAYAFI
>VV21180 GTP cyclohydrolase II
MEQPIYFYEPDENHGFLANFYPCSITVSGTCWPSSEHYYQAQKFDDVRLQ
EKVLRAEDAAQAFRLSREYQQWQRHDWYDIRVEVMRFIVREKFLQNTPLA
HQLLATGDTELKEHSHKDAFWGDGGDGHGRNELGRILMMVREELQEHAPY
NLVQFIDSAKLPTQWGTFQMYGFIEKATGKEHLALVYGDIEQQAAPLIRL
HSECLTGDALFSARCDCGFQLAKALQNIVAEGAGVLLYLRQEGRGIGLIN
KIRAYHLQDDGADTVEANEQLGFGADMRDYAFCRGILSFLGIERVRLMTN
NPRKVKALQLANIEVTERVPLQEGNNPHNHQYLRTKADKLGHMFDRNFVK
P
>VV10703 ABC-type thiamine transport system, periplasmic component
MMGISSSALAADKTLTIYTYDSFASDWGPGPTVEKAFEAQCGCDVNFVAL
DDGVSILNRLRLEGSNTKADIVLGLDNNLMAEAKATGLLAPHQVNTQALS
LPNGWADDTFIPYDYGYFAFVYNKGKLANPPKSLKELVESRDDLKVIYQD
PRTSTPGQGLMLWIKSVYGDDVAGAWQQLAKKTVTVTKGWSEAYSMFLKG
ESDMVLSYTTSPAYHLIAENDAQYAAAGFSEGHYMQVEVAAKVKSSQNSA
LADQFMSFILSDEFQSAMPTGNWMYPVTNVTLPEGYRSLTVPEKALSFSA
EEVAKQRKAWIREWQSALTF
>VV10902 Delta-aminolevulinic acid dehydratase
MSVSIQGPFPARRMRRMRKHEFSRRLMAENQLSVSDLIYPMFILMGKDRR
ESVESMPGVERLSIDLMLEEAQYLAQLGVPAIALFPVVNQDAKSLCAAEA
YNPEGLVQRAVRALKEHVPAMGVITDVALDPFTTHGQDGIIDEEGYVMND
ETTEVLIKQALSHAEAGADVVAPSDMMDGRIGRIRDALEEAGYIHTQIMA
YSAKYASNYYGPFRDAVGSASNLKGGNKKNYQMDPANSDEALHEVALDIN
EGADMVMVKPGMPYLDVVRRVKTELQVPTFAYQVSGEYAMHKAAIQNGWL
KERETVLESLLCFKRAGADGILTYFAKDVAQWLAEDNAQAAQFLKTE
>VV11622 Dephospho-CoA kinase
MALVIGLTGGIASGKTTVANLFQQHFAIDIVDADIVARQVVAPGSAGLAA
IVDHFGADILTCEGELDRGQLRQRIFAHSEEKQWLNALLHPMIRRKMIED
LAQVSSPYALLVVPLLVENQLQTLCDRVLGRGC
>VV20183 Deoxycytidylate deaminase
MTGLETIYKERAKFIILGLTGRTGSGCTTLSKLLKHNTFSELNPPKPHQA
AFPNDEERKYRIVYNYLSEHWCKFHHIRMSDVVSTFLLELPFKDFDELYK
ATLDKELGTNSKSLDVKLEQCYTEYYNKRDSAKKHAEKYKDNLYNKDIYD
FYFNELPEFTDKLRKILHRIQPGSFTKFYQIVGNNIRKSGTAESDDYDSS
KIYMFSQRVNKLIKVLRHKSKSDGENVCVVLDAIRNPYEAFFFRERYSAF
YLLSVTTENDKRINRLLSESSISKEDIKAIDSRENPDSLKGEDRFWSLDL
QRCIEISDIHLYNPDDNYKLKSLKRQLIKYISLIMHPGLVTPSQDERCMQ
IAYNAKLNSGCLSRQVGAVVTDSDKSIKAVGWNNVAQGQTPCNLRRAEDL
LTNEDESAFSLFERENTKFRTSLGNIYSFTESINKSFRGKPVSYCFKDIK
NSIDGEKNQVHTRALHAEENAFLQVSKYGGMPVKHGYLYTTASPCELCAK
KAYQLKIDSVIFIDPYPGVANDHIINCGVDTPKLKLFSGAIGRAYQQLFE
PIIPYKDELEIGLQLNVPNQKKILVEENKELILKANSLEHKAKALEKELE
KLKNQLGTVQKSHQKTLQDPAK
>VV12572 Molybdopterin biosynthesis enzyme
MRNTITLPLLGFAAYSGTGKTTLLEALLPKLTAAGLRIGLLKHAHHDFDV
DKPGKDSYRLRKAGASQMLIASRNRFALMTETPEAESEFDYLLSRFDQQT
IDVILVEGCKNIAFPKIELHREEVGKPWLYPNDENIIAIASDSGPLESAL
PQLNINDLDAICQFVLDYVHQHQQVATQNAPAACCDTLSPAFLSVAQGQE
KILSLVSTVGDIESCPIQHTYGRVLAHDVISPVNVPQYTNSAMDGYAIRS
DDLQRESYQIVAEVLAGYHYEHLLELGQAVKIMTGAPTPINGDTVVMREQ
AHQDGDKVTFNGANIKAGQNVRQAGEDLTIGSSVFTAGTRLASPEMGMMA
SLGFAQANVLRKLKVAVFSTGDEVQAPGTEQKANSIYDSNRFTIMGMLEK
LGCDILDFGILEDNEQSMIDALESAAQQADVVITSGGVSVGDADYIKLAL
DKLGQIDFWRINMRPGRPLAFGQINEKPFFGLPGNPVAVMVSFINFVEPA
VRKMQGELGWKPLKVSAIAKEDLRSRQGRTEFSRGVYELDETGRLTVRTT
GKQGSGILRSMSEANCLIEISPAVDSVKTGESVTIIPLQGRI
>VV13022 Cob(I)alamin adenosyltransferase
MSDESASSENLSTEQVKAQRHKERQQKVKEQVDAKIAQAQEEKGLLLVIT
GNGKGKSTSGFGTIARAVGHGKKCAVAQYIKGTWDNGERNLLEKLGVEFQ
VMATGFTWETQNKETDTQAAQTVWKECQRMLQDDSIDVVLFDELTYMVSY
GYIELEEVVEALNNRPRMQSVIITGRGAHRTLIEMADTVSEVKNVKHAFE
SGIKALKGVDW
>VV11352 Demethylmenaquinone methyltransferase
MDQVDVVEPMFSNFGGRASFAGQITTVKCFEDNALIRETLEQDGVGRVLL
VDGGGSLRRALLDGELAAIAEENEWEGIVVYGCVREVDELEDMNIGIQAL
ASIPVGAAMQGVGEVDVPVNFGGVTFLPEDYLYADTTGIILSQEPLSADL
EEDEEEPELLD
>VV11782 Glutathione synthase
MANLLIVTDQASDWQQYFPSEQVVDVAQYLDSDWQHNQRSVQVVNLCRDY
GYMSSGYYCSLMAGARGHRVIPTVTAINDITQPLLISSGFLKLNKLAKEQ
DSIRCKIYFGRTEHKGLEKLARRLFEQFMVPVIELKMTKNQHHWQIDSVA
PFPFQELSDAEENFFIESLEMFSNKVWRKPKQEKKYRYDIAMLIDEEEKM
PPSCPQALKRFKRAASRLGMNLETISKDEISRLGEFDGLFIRSTTNISNF
TYRFAKTAEKLGLVVMDDSESIMKCTNKVFLTELLKNNKVPAPASVILKN
FDPEWKSDLLNELDFPMVLKIPDGAFSRGVVKVRNEEELEKEATALFEKS
ELILAQAFMPTDFDWRIGILNRQAIFSCKYMMSRGHWQIYQHHNSGRVSS
GGFETLDLKQVPKNVVDVALKAANLIGNGLYGVDLKEVDGQVYVIEVNDN
PSIDHHVEDAFLGDLLYDRVMTEFLRRIQMRGF
>VV12200 D-Lactate dehydrogenase
MIKIAFFSAKSYDEASFNKVNGNKEYEFHYHDFRLRLKTSKMAQGCDVVC
AFVNDDLSSPVLEQLALGGTKLIAMRCAGFDKVDLQAAKELGLQVVRVPA
YSPEAVAEHAVGMMMCLNRRLHKAYQRTRDANFSLEGLVGFNFYGKTVGV
IGTGKIGLATMRILKGLGMEILCYDPYENPLAIEMGARYTTLQEIYQSAD
VISLHCPMSKENFHLLNEHSFEQMKDGVMIINTSRGELLDSAAAIEALKK
GKIGALGLDVYDNEKDLFFQDKSNDVIVDDVFRRLSACHNVLFTGHQAFL
THEALNNIASVTLNNVEAFFAGNTSGNELVE
>VV21372 Nicotinamide mononucleotide transporter
MELFSLFDINNTLVNIPIGDGYAMSWIEAIGTIFGLLCIWFASQEKTINY
LFGLINVTLFAVIFFQIQLYGLLLLQLFFFCANVYGWYAWTRPNAEGDLL
EVRWLSQKKMVITAGLCVCAIALLTVYIDPFFFALANIAVDTMNVFGAGL
AEPVLEPDAFPFWDSTMTVLSIVAQILMTRKYVENWVLWVVINIISVGIY
AMQGVYAMSLQYAILMFIAANGTREWARTAKRNQASTQQKSEKSADEAVA
>VV10672 Geranylgeranyl pyrophosphate synthase
MVGNVFCLFWARASARALGYQGNAHTTAAAFIEFIHTATLLHDDVVDESD
MRRGKATANAAFGNAASVLVGDFIYTRSFQMMTELGSMKILKLMSDAVNI
IAEGEVLQLMNCNDPDTTEESYMQVIYSKTARLFEAATQIGAILNDAPAE
VETALQNYGKYLGTAFQLIDDVMDYTSDGEEMGKNVGDDLAEGKPTLPLL
HAMRHTNAENAQMIREAIENANGMERLDDILAVMQQAGSLTYTEAKAMEE
ADKAIAELQVLPESEYKQALIALAHMAVKRSK
>VV13040 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase
MTKTQNVDPNEIKKFEDMASRWWDLEGEFKPLHQINPLRLDYVLSKADGL
FGKKVLDVGCGGGILAESMAKEGAVVTGLDMGKEPLEVARLHALETGTKL
TYIQSTIEDHAAENAQMYDVVTCMEMLEHVPDPLSVIRSCAALVKPGGHV
FFSTLNRNIKSYLFAIVGAEKLLKIVPEGTHDHDKFIRPSELIKMIDQTD
LCEQGITGLHYNPLSDTYKLGRNVDVNYIVHTQKF
>VV13084 Molybdenum cofactor biosynthesis protein E
MDNRISVQVEDFDIAAEYAWLSQGSAAGAVVTFVGKVRDMNLGDNVTGLS
LEHYPGMTEKALGEICDQAEQRWPLLNVRVIHRVGDLNIGDQIVYVGVSS
AHRGAAFEACEFIMDYLKTKAPFWKKERTTETTRWVESRESDAQAAERWQ
S
>VV10547 Demethylmenaquinone methyltransferase
MKDITPDICDQHEDKVTLLNLPLQNFGQKAAFFGEIVTVRCYHDNSKVRD
VLSENGKGKVLVVDGHGSCQKALLGDQLAILAIENDWEGVIVFGAVRDVA
QMSQMELGIKALGTSPFKTEKRGAGEVNVTLTMHNQMVQPKDYIYADWNG
ILISKELLQF
>VV11642 Pantoate--beta-alanine ligase
MQTFAEISALREQIKTFKREGRRIAFVPTMGNLHEGHLTLVRKAREHADI
VVVSIFVNPMQFDRADDLNNYPRTLEDDLSKLNGEAVELVFTPTPEMIYP
EGLDKQTLVEVPGLSTMLEGASRPGHFRGVATVVTKLFNIVQPDVACFGE
KDFQQLAIIRKMTTDLAMDIEIIGVPTVREMDGLAMSSRNGLLTIDERQR
APVLARTMRWISSAIRGGRDDFASIIEDASDQLRAAGLHPDEIFIRDART
LQVVNAESTQAVILMSAFLGKARLIDNQVVELVKDSKEEVDSAESESENS
H
>VV12575 ABC-type tungstate transport system, periplasmic component
MSLWQTTQEAFALLFSLDKELWEIVAVSFSVSLTAILLVLLPATFLSFLL
AYTNFRGKWLLVSFVNTLQSVPTVVIGLLLYMFLSRSGPLGDWQMLFTQK
AMILGQMLICFPVLVSMMYGALQSSDRRALETALTLGVSLPRLSGTMIWE
TRFPLMAATITGFSRIVTEVGCSMMVGGNIMGLTRNIPTAISMESHKGAF
AQGVALGIVLLTLALVLNFLLSSMRGKGYLRT
>VV10963 Thiamine monophosphate synthase ThiE
MRLLIPSAIIELTGEIQQCLLLAKQQGFAIDHIELGVSPTRTLQLISSAK
TVVFETDLIHNDSRHLGAHDFALHYHHSLALTEVSSYLGSECKAKTLLIN
LQGEQGEAFDVWQHPLADETRALRFLSRQNHSQNESVESIYRHLAWVVTL
SALDFPIEDCLTLARAMLNVSRETWVSDFALFPTPVLHLDEFGILPSHNL
EGLTKAFPRVIAQQLGLYPVVDDVSWIEKLLPLGIKTVQLRIKDPNQVDL
EQQIVRAIQLGRDYGAKVYINDYWQLAIQYQAYGVHLGQEDLQVADLAAL
TNAGIALGLSTHGYYELLRIVQLQPSYIALGHIFPTTTKQMPSLPQGLVR
LKLYQQLIDTIPYDESITGVPTVAIGGIDQSNAATVWQCGVSSLAVVRAI
TLAKDVKAVIEYFKQVMAPNTTLLRLDSVSTHSLEPTSEANHVG
>VV10625 Dihydroneopterin aldolase
MALDKVFIEQLEVITTIGVYDWEQQIKQKLVLDIEMAHDNRPAGKSDDVA
DALDYAQVSEAVLNHIENGRFLLVERVAEEVAELIMTQFSVPWIRIRLAK
PGAVPQARAVGVVIERGQA
>VV21615 Coproporphyrinogen III oxidase
MTLTLDKYDQSIIGIDTPDPLRFAFAQKHSAHAGGMSRPLNPSQLVEQFN
TLTQSNEFSRKKRCLYIHIPFCRVRCTFCNFFQNAASRQLVDGYFEALLK
EIAIKSALPWTQSGVFHAVYVGGGTPTDLSPAQVRQLGEAIRSHFPLSAD
CEITLEGRINRFSDEMYDGAMKGGFNRFSFGVQSFDTLVRRSAKRLDDRE
KVLTRLSELASYDQAPVIVDLLYGLPHQTRDILLQDLNDFISTGAHGLDL
YQLVVGGSAPMLNLVEKGKLPPPATTPDKASMYEIGVNFMRQHHLKQLSV
NHWATDNRERSLYNSLAKTYAEVLPIGCGAGGSIGGYGMMQHRSLDAYMA
AINHGQLPLMMMTQQHPLEAIFAALKSGFDRGVVMADKLPEFMGDNVFDF
LQPLFRLWQERGLVELNERSATLTLAGSFWAVSLAQACIQILSSEYQSAH
QTQAIAQ
>VV12022 5,10-methylene-tetrahydrofolate dehydrogenase
MTAQNIDGTLISQTVRSEVAARVKARVAAGLRAPGLAVVLVGEDPASQVY
VGSKRRACEEVGFVSKSFDLPASTSEEELLALIDELNNDAEIDGILVQLP
LPAGIDSTHVLESIHPEKDVDGFHPYNVGRLAQRIPKLRSCTPKGIITLL
ERYNIALRGKHAVIVGASNIVGRPMTLELLLAGCTTTTCHRFTKDLEGHV
RQADVLVVAVGKPNFIPGEWVKEGAIVVDVGINRLESGKLIGDVEYNKAR
ERASFITPVPGGVGPMTVASLIENTMLACEQYHTK
>VV11519 Coproporphyrinogen III oxidase
MLTPPALSLYVHIPWCVQKCPYCDFNSHALKEQIPEQMYINALLEDLDRD
IEKYQLHRAPRPLHSIFIGGGTPSLISAEGIRDLLQGIEKRIPFTPSIEI
TMEANPGTIEAERFAGYRKAGVTRISIGVQSFEQQKLERLGRIHGQDEAV
NAAKLAHQIGLNSFNLDLMHGLPDQSIEQALADLDKAIELNPPHLSWYQL
TIEPNTMFYYKPPALPDDDQLWDIFERGHQKLTQAGYVQYEISGYSKPGY
QCQHNLNYWRFGDYLGIGCGSHGKLSFADGRIIRTTKIKHPKGYLAAHQN
MVKPYLDSEQLVEEIDRPFEFFMNRFRLMEACPKQDFIDTTGLPLSFIET
TIQWAVEMGYLNDNETSWQITEKGKLFLNDLLEAFMAEE
>VV21237 Pyridoxal/pyridoxine/pyridoxamine kinase
MQGILSIQSHVAYGHAGNSSAVFPMQRMGFEVWPIHTVQFSNHTQYQEGW
TGRAFSADDISELVRGLNNIGALEKCQAVLTGYQGSAEQCLAVEETVTKV
KQANPDALYVCDPVMGAPDKGCIVAPGIAENLLNRLMPMADVIVPNQFEL
SQFAEMEIHTLDDAIIACQRALAKGPKVVLVKHLYCLSDESFNMLLATQE
GTYLAKRPHFEFAKAPVGAGDLISAIFTAGLLKGWTPKQAFQHCHDACYG
VLNATYQAGEWELQTIAAQQEFVEPSKHFPLEEVTLKTVE
>VV10317 Thiamine monophosphate kinase
MSGEFNLIEKYFVGRQAQRKDVHLAAGDDCALVKPPSNVQIAISTDTLVC
GTHFLADADPAWVAHKALASNISDLAAMGATPAWVSFALTMPLADEAWLA
PFCDGFFKLADYFGIQLIGGDTTKGPLSLTMTVQGFVPEGKAITRSGAKP
GDYVFVTGTLGDAKAGLDVILDSNLRTRPAAQALEKAHYMSMPRILAGQA
LVGLASAAIDISDGLIADLGHILNRSQVGVSLDVSKLPISSELLSFLTER
EMALQYALTSGEEYELCFTVPEEARGTIESALAHVGCKVTCIGQIRPHGF
FELHDDGTKLNWDLSGFDHFKA
>VV11988 Erythronate-4-phosphate dehydrogenase
MDLGFATMKILVDENMPYAETLFSQLGEVILKPGRSLTADDLVDIDALMI
RSVTKVNAALISKANKLKFVGTATAGMDHVDQALLKEKGIYFTAAPGCNK
VGVAEYVFSVMMVLAQQQGFSVFEQTVGIIGAGQVGSYLQQCLQGIGIKV
LINDPFKQEEGDEREFTSLDRLLQEADVITLHTPITRDGKYPTHHLINEE
ILNSLRADQILINAARGPVVDNQALKRRLQQADGFMAALDVFEFEPEVDM
ELLPLLAFATPHVAGYGLEGKARGTTMIFNSYCEFIGNELRAHASDLLPT
APVPKVVLDRKWDEATLHTLTQLVYDVRRDDAQFRREIGAPGAFDLMRKE
YWDRREYSAVTLVGSAQCRLKPLAKLGFQVEVSQ
>VV12265 Para-Aminobenzoate synthase, component I
MQQSNSLSQIKQMNNSINTAISSKTLPYQTDLSQQWFDTIQHQPWAMLLR
SASPTHVDSRFDILVAKPVATLETRGAVTEINTNDEVIESKDDPFTLLAR
YQQRFTPALSSDEEIPFIGGALGYFSYDLGRCVEKLPEIATQDIAAPDMA
VGIYTWALIVDHQTQTAQLVGQDVEQAYQWLSTQTKADDATFALTSDWQS
NMNRRDYQSKFDCVQEYLLSGDCYQINLAQRFHANYQGSEWQAYQKLEQS
NQAPFSAFIRLKDAAILSVSPERFLELKKRVIETKPIKGTRPRHNDEQQD
KQAALELANAEKDQAENLMIVDLLRNDIGRVAKPGSVHVPKLFDIESFPA
VHHLVSTIRAELAAQYTAADLLRACFPGGSITGAPKVRAMEIIEELEPHR
RSAYCGSIGYISRHGRMDTSITIRTLVAEQGKLFAWAGGGVVADSQCDAE
YQETLDKLSKILPTLQ
>VV10828 DNA/pantothenate metabolism flavoprotein
MQTLAGKKILLGISGGIAAYKCADLTRRLKERGAEVQVVMTKAAKEFITP
LTMQAVSGRPVSDSLLDPAAEASMGHIELAKWADLILLAPATADLIARMA
AGMGNDLLTTLVLATDAPVAVSPAMNQQMYRNVATQENIATLSRRGMEIW
GPAAGEQACGDVGPGRMLEPMQLVALCEQFFQPKPLQDKSILITAGPTRE
AIDPVRYITNHSSGKMGYALAQAAMQLGANVTLVSGPVSLPTPVNVNRIN
VDSAQEMYDAVMAQASDHDIFISCAAVADYRPATIAEQKLKKTDDSDEMT
ITMVKNPDIVASVSAMTENRPFTVGFAAETNDVEVYARRKLEKKKLDLLC
ANDVSVEGQGFNSSDNAITLYWSQGEKALPLNSKAVLSMEILKQIQTLMG
H
>VV12173 Quinolinate synthetase A
MSHILDKIDTVYPFPPKPIPLTQDEKAAYIASIKQLLNEKDAVLIAHYYT
DPEIQALAEETGGFVGDSLEMAKFGNRHPAGTLIIAGVRFMGESAKILTP
EKRILMPTLEAECSLDLGCPADKFTEFCDAHPDHTVVVYANTSAAVKARA
DWVVTSSIALEIVEHLDAEDKPIIWGPDRHLGSYIANKTGADMLLWQGEC
VVHDEFSADALRKMKAVYPDAAILVHPESPASVVELADAVGSTSQLIKAA
KELPQQKMIVATDKGIFFKMQQLVPEKELIEAPTAGAGATCRSCAHCPWM
AMNGLKAIETALREGGEQHEIFVDEALRVKSLIPLNRMLDFAEKLNMQVK
GNA
>VV10897 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase
MQHSFGHSVAVRKATAWLSLFLFWPFFYEIGDYLPVGSPIWVDFLVCFAS
LFEEVRMHTCPLCQHDQILHYFTDKRREYLQCARCELVFVNPEQRLDAKT
EKSHYDLHENNPLDLGYRRFLSRITDPLLERIAPQSNGLDFGCGPGPTLS
LMLEEHGHVMSLYDLYYHPDRSVLRREYDFMTATEVIEHLYEPNVVWQQW
LNLVKPRGWIGLMTKMVIDREAFANWHYKNDPTHVIFFSQATFQYLAERD
KLELEFIGKDVILLRKTQ
>VV11122 Porphobilinogen deaminase
MTHSTPIRIATRKSPLALWQAYYVKDALQKAHPGLEVELVTMVTKGDVIL
DTPLAKVGGKGLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTIC
EREDPRDAFVSNTYHHVDELPQGAVVGTCSLRRQCQLKAYRPDLVIKELR
GNVGTRLSKLDAGEYDAIILAAAGLKRLELEERIRSFIEPEQSLPAVGQG
AVGIECRTNDERILKLLEPLNHADTADRVKCERAMNLTLEGGCQVPIGSY
ALLEGDEIWLRALVGEPDGSEIVRGEIRGPRAQAEQLGVQLANQLLDEGA
REILTKLYQDHE
>VV12786 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase
MSYSTNKALVLGGARSGKSRFAEQLARQWSQQHDAKCHYVATAVPFDQEM
AERIHHHQQQRGQGWCEHEAPLYLAERLSQFGADDVVLVDCLTVWLNNWL
FEFGEQASNEKLEQKVAQLASVVKESPAQIILVSNEVGLGVVPLGQISRL
FVDNAGRMNQSLAKICDNVTLVAAGLPLILKSSGHQ
>VV10962 Dinucleotide-utilizing enzyme
MLVDRLFTRYQRQIALTEFGESGQANLLQAHVLIIGCGGLGNAAALYLAA
AGVGHLVLVDDDVVEESNLQRQIAFRQQHLASPKVDALAEQLKQLNAELR
VRTISHRLDEERLNLEVMLADIVLDCTDNFPSRQLINQACLNQRTPLVSA
SAIGWKGQFIAFDFSSYHSIQSQQDTSSAASSVNPPCYHCLFPFAENAMQ
TKCSDAGVIGPVVGLMGNYQAIATIQKLATGAFQTTCHQLHLFDGLKLSW
QHLAVVKDPSCRVCQIQKQESSNEHHSN
>VV13169 O-succinylbenzoate synthase
MKSAKLYRYTLPMDSGVVLRDEKLTERVGYIIELNMNGQKGYGEVSPLPG
FSLETIEEAGIEAQAQLELWMNTDHPIDYDALLPSVAFGLSTAMYELEGK
LPRDGHYLPAPLCTGDPDELIPVLNAMQGEKVAKVKVGLYEPIRDGMLVN
LFLESIPDLTLRLDANRAWTPEKAQQFAKYITPSLRQRIVFIEEPCQKPG
DSLSFAINTGIAIAWDETLQHALHRPDFALDDLTGVKAIVIKPTLIGSLP
RCIALIKKAHSLGIKAVISSSIESSLGLTQLARFAKWQLPDVTPGLDTIS
LFQSQLMVGWPKCSLPIASLEEQQLVWHS
>VV11164 4-hydroxybenzoate polyprenyltransferase
MSVEKAKAYWQLMRMDRPIGTLLLLWPTLWALIIAAEGTPDWHVLLVFVL
GVVLMRSAGCVINDFADRKVDGHVKRTQQRPLPSGRVTAKEAIILFLLLG
ISSFLLVLTMNPLTIQLSFAGIVLAFIYPFMKRYTHLPQLFLGLAFSWAI
PMAWAAQANELPWVVWFVFAINALWTIAYDTQYAMVDRDDDVHIGVKSTA
ILFGRHDKLIIGLLQLLTLVMLVWLGLHYQLGQSFYWSVLAAGALFVYQQ
HLIRHRQRELCFQAFLNNNYVGMVLALGLFVAFW
>VV11077 Ketol-acid reductoisomerase
MANYFNTLNLREQLDQLGRCRFMDRSEFATEADYLKGKKVVIVGCGAQGL
NQGLNMRDSGLDVAYALRQAAIDEQRQSYKNAKENGFEVGSYETLIPQAD
LVVNLTPDKQHTNVVETVMPLMKEGAALGYSHGFNVVEEGMQIRKDLTVV
MVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGWDIAKAWAAATGG
HRAGCLESSFVAEVKSDLMGEQTILCGMLQAGSIVCYEKMVAEGIDPGYA
GKLLQYGWETITEALKFGGITHMMDRLSNPAKIKAFELSEELKDLMRPLY
NKHMDDIISGHFSSTMMADWANDDANLLGWRAETGETAFENYPSTDVEIS
EQEYFDNGILMVAMVRAGVELAFEAMTASGIIDESAYYESLHELPLIANT
IARKRLYEMNVVISDTAEYGNYLFANVATPLLREKFMPSVGTDVIGKGLG
ETSNQVDNATLIAVNETIRNHPVEYIGEELRGYMTDMKRIAVGG
>VV21122 Pyridoxamine-phosphate oxidase
MELADIRREYTKGGLRRKDLKNDPIDQFNFWLEQAIKANLSDPTAMTVAT
VDKDGMPFQRIVLLKNVDKDGFVFYTNLGSRKAQHLEHNSKISLHFPWHP
LERQVHITGVAEKLTAMENMKYFTSRPKESQLAAMASRQSSRISARGVLE
GKFLELKQKFANGEIPVPSFWGGFRVKPQSIEFWQGGEHRLHDRFLYSQE
QGEWHIDRLAP
>VV20846 Glutathione synthase
MRIAILSRNENLYSTMRLKQAGEARGHEVDVIDTLHCYMDITSNNPKIRY
KGEELPQYDAIIPRIGASVTFYGTAVVRQFEMMGTFVVNESVAISRSRDK
LRSLQLLSRKGIGLPRTGFAHHPDNIQDVIRNVGGAPLVIKLLEGTQGIG
VVLAETNKAAESVIEAFMGLKANIMVQEFIEEAKGADIRCFVVGNKVIAA
MKRQAKEGEFRSNLHRGGSAQLVRLSKEERATAINAAKVMGLNLCGVDIL
QSKNGPVVMEVNSSPGLEGIEQATNKDVAGMIYEFIEKNAKPNSNRTKGR
G
>VV10624 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokin ase
MNTVYIGVGSNIEREKHARAAWQELTLLGEALQASPIYECAAVGFDSHAF
FNFVIRLNTSMTLEELASQLRQIELRWGREENAAKYQDRTLDLDIVLFGE
CISSQKPELPRSDIFKYPFVIQPLYDLQPDLVIPGDGRTVEEIWQTARDL
DTLKAVDFSL
>VV11548 5-formyltetrahydrofolate cyclo-ligase
MQNLSRQDIRTLIRQRRNQLCSDTQYQAALDLTAHFAQLDELTDAQHIAL
YLSADGELDTKPLIEWLWELGKQVYLPVIHPFSKGQLLFLHYHRHTDLIY
NRYGILEPKLDKRHIIPLAELDLICTPLVAFDSTGQRLGMGGGYYDRTLE
RWFRTGLGAKPIGIAHDCQHVEQLPCEVWDIPLPKIVTPSQIWQWENDV
>VV10508 FAD synthase
MELIRGIHNIKPQHRGCVLTIGNFDGVHLGHQEVLRQVSLRAREMSLPSV
VMTFEPQPLELFAKEKAPARLTRLRDKFVQLGKLEIDRLLCVNFNRHFAS
LDADAFIRDLLVERLGVKFLVVGDDFCFGKARQGNFAMLQEAGKKYGFTV
VNTQSFCLAQLRVSSTAIREALAHDQLAVAAQMLGRDYSISGRVSHGRKL
GRTIGFPTANIPLKRCVSPVSGVYVVQALGLDNKPIGGVANIGQRPTVNG
VRQQLEVHLFDFQANLYGKQLEVVLLHKLRDEKKFESFDALKQQIELDAE
AARVWLRQLKR
>VV10894 Oxygen-independent coproporphyrinogen III oxidase
MSNQNLESNQQIVWDQAVLDKYNYSGPRYTSYPTALEFHEAFTISDYDMA
CTQYPERPLSLYIHIPFCHKLCYYCGCNKVITRHSHKADEYLDVLEHEIR
QRASLLQGRRVTQLHFGGGTPTFLSAKQITRLMTLLREEFTFTAEAEISI
EVDPREIALEMLGHLRAEGFNRLSIGVQDFNKEVQKLVNREQDEAFIFAM
VERAKQLGFRSTNLDLIYGLPKQDRDSFAKTLEQVLSMQPGRLSVFNYAH
MPQLFAAQRKIKDEDLPKAEEKMAILQNTIATLTDAGYQFIGMDHFALPD
DELAVAQRNGVLHRNFQGYTTQGECDLVGFGVSAISMIGDAYAQNQKELK
KYYAQVNDLRHALWKGVALDGDDLLRREVIKQLICNFKLDKVAIEKQFAV
TFNQYFKEDLQLLQTFIDDALVEVDEQAIRVTLRGRLLIRNICMCFDKYL
RAKARQQQFSRVI
>VV20975 Phosphoglycerate dehydrogenase
MKIAILDDYQDQVRQLECFAALAPFEVTVFHHTETDEAILASALTEFDAL
VLIRERTAITASLLAKLPNLKLISQTGKISNHLDLHACNHANVAVAEGVG
SPIAPSELCWALIMAASREIVSYAQQLQQGEWQQNQTHRLGRTLHGQTIG
IWGYGKIGQRIAGYAKAFGLQVMVWGSESSRRQAQEDGFLAADSKEAFFQ
QCDIVSLHLRLNAATHAIVKASDLAAMKPGSLFVNISRAELVEAGALFQE
MQLRSDKFAAIDVYHHEPATMAQEPILTLPNVLCTPHIGYVEQNSYELYF
RYAFDNIVAFAHGQAQNIVNPEVLSRTE
>VV12788 NaMN:DMB phosphoribosyltransferase
MLEQQFAAEIQHIIDNKTKPLGALGQLEQVALQLALIQSQGKEQAATHIE
LKQPQMLLFAGDHGVADEGVSIAPSAVTQQMVLNFLAGGAAINCFCALHS
IDLTVVDCGILLPVDSDAPNLILRRLGSRTANFAFESAMTIEQVEQALRN
GQQIAAEKIAQGADLLMFGEMGIANTSSAAALLSALSGHEVDHCVGRGTG
INEEQLSHKIKVVAQGVGRCEGLSVNAILAEVGGFEIVTMAGAFIAAAEH
KTPVLVDGFIVSVAAYIATLLKPEVRDYLLFAHRSEEQGHQIVLSLLEAK
PLLDLGLRLGEGTGAALAYPLLKAAAQFYNNMASFESAGVTV
>VV12813 Phosphoserine aminotransferase
MEQNTDNVFNFSAGPAALPKPVMQQAQQELLNWQGLGTSVMEISHRSKEF
IAVAEQSEQDLRDLLNIPDNYKVLFCQGGARAQFAAVPLNLLGDATTATY
IDAGYWAESAVEEAKKYCQPDVFVAKAEKEGKQAVLPASEWQIHPDAAYV
HFCPNETIDGIEINDLPVTDKPIVADMSSTILSREIDVSKYGVIYAGAQK
NIGPSGIAIAIVRDDLLGLAKEVLPSILNYKVLAEQDSMFNTPPTFAWYL
SGLVFKWLKAQGGVKAIEQVNREKAAILYNYIDESDFYINNVHPDNRSLM
NVPFQMVKPELDAKFLKEAEALGLKSLKGHRVVGGMRASIYNAMPIEGVK
ALVDFMRQFEQENA
>VV10319 Riboflavin synthase beta-chain
MKVIEGGFPAPNAKIAIVISRFNSFINESLLSGAIDTLKRHGQVSEDNIT
VVRCPGAVELPLVAQRVAKTGKFDAIVSLGSVIRGGTPHFDYVCSEMNKG
LAQVSLEFSIPVAFGVLTVDTIDQAIERAGTKAGNKGAEAALSALEMINV
LSEIDS
>VV11994 Folylpolyglutamate synthase
MWLDLFSHIHTSAIDLGLDRVQAVALKANLTKPAPTVITVAGTNGKGSTC
ALMEAILLDAGYSVGVYSSPHLIRYNERVRINGQDLADEKHCEAFDFIEQ
QRGDISLSLFEYGTLAALRLFQTEKVDVVLLEVGLGGRLDATNVVDHDVS
VITSLALDHVDWLGDDINVIGFEKAGIYRSGKPAICGQPTPPSTVAAHAD
DIGAEFYQVGIQFDYQLSGEGWRWQHGAFALEDLPLPGLPLPNAATALMA
LGASNLELSDINIVNGLKNAKLAGRMQVLQTAPLILLDVAHNPHSAEYLV
TQLQSRYQGKTIHAVIGMLKDKDIKSTLEVLAPVTRHWYPASLTGPRAAT
AEELIQYLPQGTQSYTDPAHAFDQALSQAQSDEIVLVVGSFHTVGEVLEH
WQQNKGN
>VV20330 Cobyric acid synthase
MEAKVTTLMVQGTTSDAGKSVLVAGLCRVLARKGVNVAPFKPQNMALNSA
VTKEGGEIGRAQAVQAQACRIEPSVHMNPVLIKPNSDTGAQIILQGKALT
NMDAYGFHNYKKVAMDTVMDSFARLKDEYQAIMIEGAGSPAEINLRQNDI
ANMGFAEEADVPVIIVADIDRGGVFAHLYGTLALLSPSEQARVKGFVINR
FRGDIKLLESGLDWLEEKTGKPVIGVLPFLHGLNLEAEDAITSQQELSGE
VKLKVVVPVLTRISNHTDFDVLRLHPQIDLRYVGKGERLEHADLIILPGS
KSVRDDLRYLREQGWDKDILRHLRFGGKVLGICGGYQMLGESISDPFGVE
GEPGESVGLGLLKTRTELTQDKCLINTKGQLSLNGKHVNVTGYEIHVGRS
QVNEYQPITNDDGQLEGALSECGQIMGSYLHGFLDSEAVLELICEWVNGV
RIKAQNHQQLKEQAIDRIADAIEEHLDLSQLGI
>VV11221 Phosphoglycerate dehydrogenase
MHQSKHKIFIVTEDNETYRQLLADHALPDLALTEDIEQANIILAAPPHIA
PRLSECHQLEWLQSTYAGVNALMQPELRRDYKLTNVRGIFGPLIAEYVIG
YAIQHYRHLARYAEQQQQRLWQPHPYSSLEGKTITILGTGSIGNHLAHAC
SAMGLHTIGVNRTGIPPNGSHFQQTYHINELAAALKQAHIVVNTLPSTKH
THHLLNQASLSHCRHALLFNVGRGDVIDNAALLLAIKNHWVEHAFLDVFE
QEPLVTDHPFWGLKQITITPHIAALSFPEKVMALFAENYHRWLEGYPLNH
QVSFTKGY
>VV10322 Riboflavin synthase alpha chain
MFTGIIEAVGTLAAITPRGEDITVTVNTGKLDMSDVKLGDSIATNGVCLT
VIDFSDRHYSADLSLESLKKTGFANYQVGDKVNLEKAMLPTTRFGGHIVS
GHVDGVGEIVERNQVGRAIEFWVAMPESLSKYVAEKGSITVDGISLTVND
LRKNAFKLTIVPHTGDETTINDFQVGRKVNLEVDVLARYMERLLLGQQAQ
SNDESRITMEFLQQNGFA
>VV12560 Riboflavin synthase alpha chain
MFTGIVQGTAEVVIIEAKESFQTHTIRLCGEMLSGLAIGASVAHNGCCLT
VTKIADDLVSFDLMQATLKLTNLGTLRVGDRVNIERAAKFGDEIGGHSMS
GHISTTATIDQIIDTPNNRTIWFKLPYDDAMKYILAKGYIGVDGCSLTIG
EVEAERFSVHLIPETLNRTLFGQRNVGESVNIEFDPQTQAIVDTVERVLM
SKGVVA
>VV13172 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase
MNHDQAVLNRIWCETLFEELYRFGVRDVCVAPGSRSTPLALEANAHTRLK
LHTHFDERGLGFLALGLAKASQRPVAVVVTSGTAVANLLPAVAEAGLTGE
KLVLLTADRPIELVGCGANQAIAQQGIFSNHVCASLNLPSPNTQTSLNWL
LTSVDQVLHQQAVSGHAVHINCPFPEPLYSNAPKSIYQSYIDTVDVWRAE
GGIYSNKQMPLPMPPSLAEIEQRKGVVVIGSVTLQEAKQAHQFGAQMGWP
VLCDPQSGTTSDWSGFDIWLQNPAARAQLSQCDLIIQFGRRLVSKRLHQW
LEQQVQAGCDYWYVSPDFERDNQSHLPQQHFVCSIAAWLNVVTNREVQPV
AWANELPRFSAEVNKQAREIAQSSLCEMMIALHLSSLVGSADLFLGNSLF
VRMVDMVGQLHGVETFTNRGASGIDGLFATASGVQRARSNPMLLMIGDTS
ALYDLNSLALYSHQETPVVIVVTNNDGGAIFDLLPVPPQQKQALYQMPHG
YRFEFAAKQFGLDYVCPTSMTELTERIVGHFAHGCGALLVEVNTPPNQAS
QHIKQLADHVRSLV
>VV10315 Deoxyxylulose-5-phosphate synthase
MTLDISKYPTLALAETPDELRLLPKETLPTLCDELRTYLLNSVSQSSGHL
ASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRREQMPTIRQ
KGGLHPFPWREESEYDTLSVGHSSTSISAALGMAICAEKEGQNRKVVSVI
GDGAITAGMAFEAMNHAGDVHSDMLVILNDNEMSISENVGALNNHLARVL
SGNLYTSIREGGKKVLSGVPPIKELVRRTEEHLKGMVVPGTLFEELGFNY
IGPIDGHDVVELVKTLKNMRELKGPQFLHIMTKKGKGYEPAEKDPIGYHG
VPKFDPAHNSLPKSSGGKPSFSNIFGDFLCDMAAQDPKLMAITPAMREGS
GMVRFSKEYPEQYFDVAIAEQHAVTLATGMAIGGYNPIVAIYSTFLQRGY
DQLIHDVAIMNLPVMFAIDRAGLVGADGQTHQGAFDLSYMRCIPNMVIMA
PSDENECRQMLYTGHKHQGPSAVRYPRGNGMGTPIESEFTALEIGKGRLV
RQGEKVAILSFGTFLANALEAAEALNATVADMRFVKPLDEALLRQLANEH
DVLITIEENAIAGGAGAGVIEFMMQEKIMKPVLNLGLPDKFIHQGTQEEL
HEELGLDAKGIEQAIRHYLAK
>VV12940 Dethiobiotin synthetase
MMKAFFIAGTDTDVGKTVASKAILHALAAKDLRTIGYKPVAAGSDKTPEG
WRNSDALHLQKAATVAVDYEDINPYALELPASPHIAAKHEKVEIDYAVLS
RKLAQHKENADVVLVEGAGGWRVPVSDTDSLSTWVKQEDLPVVLVVGIKL
GCLSHALLTAEVIKADGLNLVGWVANRVNPGTEHYAEIIDMLEERLEVPK
LGEIPYIPSAKRKDLGKYINADVLLEL
>VV12573 Molybdopterin-guanine dinucleotide biosynthesis protein A
MGGKDKGLIALNNKPLIEYVIDRLTPQTSNILINANRNQDDYQQYGPVFG
DHFQNFPGPMGGIHAGLLHASTDWVGFVPCDCPRINEDLVERFCRAVTDE
TDILVAHDGNHQQPVFTLYHKRVLPKLTAFLERGDRKIILLYKECHTQYV
DFSDSPDCFVNLNTPEELTQFGQLES
>VV12943 Biotin synthase
MEVRHNWTHAQVRELMEMPFMDLLFEAQQVHRQYHPKNYVQVSTLLSIKT
GACPEDCKYCPQSARYQTDVEKERLMKVERVLDAAQKAKNAGSTRFCMGA
AWKNPKERDMPLLTDMIKGVKDMGLETCMTLGMLTPEQAKQLASAGLDYY
NHNLDTSPEYYGNIITTRTYQDRLDTLSHVRDAGMKICSGGIIGMGESAN
DRAGLLVELANLPTHPESVPINMLVKVKGTPLETAEEVDPFDFIRLIAVA
RIMMPTSAVRLSAGRENMNEQMQTLCFMAGANSIFYGCKLLTTPNPSEDK
DMQLFNKLGINSQQVSQKPDEITENELLDRVVESVAARPTKDDLFYDASL
>VV10819 Phosphopantetheine adenylyltransferase
MSKKALSRVVYPGTFDPITNGHLDLIERAAKMFDEVIIAVAASPSKNTMF
TLEERVDFARQVTRHLDNVTAQGFSGLMVDFARAVDANVLIRGLRTTVDF
EYEFGLTNMYRRLLPGLESVFLTPSEEHAFISSTIVREVAIHGGDVTQFV
PTVVAEALHQKKKV
>VV11163 4-hydroxybenzoate synthetase
MNQPNSLYLALLIEAKWQNPEDFHFSSDFAKHWLLEQGSLSRRLARHCQH
LTVELMRNEKSGMGQLTRQETQGLSPEICLIREVVLSGDQTPWVLGRTLI
PETTLADQPYDLATLGDIPLGLTVFSAEQVERDALQVAWIETPQGRLLAR
RSRLWMNHKPMLVAELFLPDAPIYSRESV
>VV13064 Anthranilate/para-aminobenzoate synthase component I
MNKAINITTLGQLELLSTTVPYHSDPTRLFHTLCENKRDSLLLESAEIDS
KQDLKSLLIVDSAVRMVCHGHVVTMTALSDNGKNLLTHLTKNVAQEVEHQ
FDGQQLTLTFSSPDDRLDEDSRLREASSFDALRLVQHSFDLAEKDKHAIF
IGGLFAYDLVANFEPLGEAHAINQCPDYVFYVAETLMVVDHQTESCHLQA
TLFADDSQKEALNQRIEQIRTLCATPKALPKAIHLDKVEVDTNISDDAFC
QVVRDLKQYVVKGDIFQVVPSRRFTLPCPSPLAAYKELKVSNPSPYMFYM
QDELFTLFGASPESALKYETQTNQVEIYPIAGTRRRGKRANGEIDFDLDS
RIELELRTDKKENAEHMMLVDLARNDVARISRAGTRHVADLLKVDRYSHV
MHLVSRVVGQLRDDLDALHAYQACMNMGTLTGAPKIRAMQLIRDVEGARR
GSYGGAVGYLTGEGTLDTCIVIRSAYVENGIAQVQAGAGVVFDSAPQAEA
DETRGKAQAVISAIQKAHKES
>VV11678 Glutamate-1-semialdehyde aminotransferase
MPATWSEQSEEDKPMTKSAELYQKAQQTIPGGVNSPVRAFNGVGGSPIFV
ERADGAFIFDADGKAYIDYVGSWGPMILGHNHAVIREAVIEAAQRGLSFG
APTEMEIKMAELVSELVPSMEQLRMVSSGTEATMSAIRLARGFTGRDKIL
KFEGCYHGHADSLLVKAGSGALTLGQPSSPGVPADFAKHTLTATFNDLDS
VRELFAANKGEIACIIVEPVAGNMNCIPPVEGFHEGLREICDQEGALLIF
DEVMTGFRVALGGAQAHYNIKPDLTTLGKVIGGGMPVGAFGGRKEVMQYI
APTGPVYQAGTLSGNPVAMAAGYACLTLLREEGNEKRLASKTKHLADGFK
SLAAQHGIPLVVNQVGGMFGFFFTEQEQITCYEDVTKCDIERFKRFFHLM
IDHGVYLAPSAFEASFTSLAHGSKEIEATLEAADRCFAILAAESK
>VV11691 Dihydropteroate synthase
MGILNVTPDSFSDGGQFNALDAALAQAERMIAAGVSIIDVGGESTRPGAP
EVSLEEELKRVIPAIQAIRQKHDVWISIDTSKAEVMKQAIEAGADLINDV
RALKEPGALAVAAKAQVPICLMHMQGQPRSMQHNPSYQDVLKEVSEFLEE
RVAACEEAGIAKELLILDPGFGFGKTIEHNYHLLAHLEAFHQLGLPILAG
MSRKSMVFKLLNKKPAECMVASVTCATIAAMKGAQIIRVHDVEETVEAMR
VIQMMHKNI
>VV11056 Coproporphyrinogen III oxidase
MSTIDKEAVKLYLMQLQDQICQRLEQEDGKATFIEDAWYREPGDRLGGGG
RTRVMRDGNVFEQGGVNFSHVQGNAMPASATAHRPELAGRRFEAMGVSLV
MHPHNPYVPTSHANVRFFIAEKEGEAPIWWFGGGFDLTPFYPFEEDCQFW
HNTAKEVCAPFGADVYAQHKAWCDDYFYLPHRGETRGIGGLFFDDLNQWE
FDKCFDYIKAVGEGYCDAYLPIVERRKVTEYGEREREFQLYRRGRYVEFN
LVYDRGTLFGLQSGGRTESILMSMPPLARWEYSYEPQADSPEASLYQHYL
KPREW
>VV20544 Molybdopterin biosynthesis enzyme
MGCCDAPGLMPIEDAMEKMLSRIKPIQTTLKLPLAEALGYVLAEDILSPI
NVPPFDNSAMDGYAIRIADLEHNQPLPLAGKSFAGQPFDGEWPQNSCIRI
MTGAKIPAGCDAVIMQENTEVSDEGIVIQQCQIKPNENIRPTGDDIQAGD
LVLAQGARLTPRDIPMIASLGISHVTVVRKPRVAFFSTGDELKSLGEPLL
EGQIYDSNRYGIKPLIENFGCEAIDLGIIPDCPETLKATFEKAQSLADVV
VTSGGVSVGEADYTKDILEQLGEIGFWKLAIKPGKPFAFGKLSTAWFCGL
PGNPVSAVLTMYVLVQPMLAKLAGHSQWKAPESIPATTRTAFKKAPGRTD
YQRGIYTIENGQFFVETTGNQSSGAFRSMSLANCFVVLERERGRVEVGET
VNIELFNSTLF
>VV11462 Lactate dehydrogenase
MSLPVVVFLDRATIPAHITLPTLAFEHRWVEYDFTSPEQVIERLQAADIV
ITNKVLLDQALLAQLPNLRMIAVAATGFNNVDVDFCAEKGIAVANVRGYA
TRSVPEHVIAMLFALRRNLFGYHQDIAAGVWQQDKQFCFFTHPIGDVAGS
TLGIIGSGALGQATAQLAQALGVKVLFAERKGQSDCRQGYHRFEEVLAQA
DAISLHCPLSAQTHHLIGAAELASMKSNAILINTGRGGLVDEQALVEALK
KGDIAAAGVDVFSTEPADETNPLLANMHLPNLLLTPHVAWGSDSAITQLC
EILLENINAYWRGETLNRLV
>VV21484 7-keto-8-aminopelargonate synthetase
MSSAFYQQIRDQLEDVKAEGLYKSERIITSHQQAAVKIASGEEVLNFCAN
NYLGLANHPALIEAAKEGMDGHGFGMASVRFICGTQDIHKELEQKLSQFL
GKEDTILYTSCFDANAGLFETLLDKEDAIISDALNHASIIDGVRLCKAMR
FRYSNNNMAELEEQLIAADAAGARHKLIVTDGVFSMDGVVANLPAICDLA
DKYNALVMVDDSHAVGFMGKNGAGTHEYHNVMDRIDIITGTLGKAMGGAS
GGYTSAKAEVIDWLRQRSRPYLFSNSVAPAIVAASIRVLDLLQESGDLRE
RLWENAAHFRTRMEAAGFTMGGADHAIIPIMLGDAKVAAEFAERALAKGI
YVIGFSFPVVPKGQARIRTQMSAAHSREQLDRAIDAFIEVGKDMGII
>VV12782 ABC-type cobalamin transport system, permease component
MELHQLIAHKEKRWRATLLVMLAVLLVLSALYLMVGEVFLSPFSSLSSFE
HKLLVDLRLPRLVAAMVIGAALAVSGATLQVLLGNVLAEPGVLGISGGAS
LAMVIALFLLPVMPTPTVFMLAAIIGALVFTLILVGMARAMHLSTSRMLL
VGVALGILSGAFVTWAFYFSDDLSLRQLMYWLMGSIGGASWHHHLVTLVL
LPVLVWLCLQGQTLDKLMLGETHAAQLGVDVHKVRWRLILAISILIGCAV
ALGGIISFVGLVVPHLLRMAFGSENRFLLPLSAFAGATLLVFSDIWARTL
LDSAELPLGVMTTTIGAPIFIWMLIRSHDAH
>VV11841 Putative p-aminobenzoyl-glutamate transporter
MSSSASIKQTSPKKPLFTRFLDTVEYLGNLLPHPITLFAIFCLAILISSG
IAGYFEVSVVDPRPEGAKGRAADGMIHVVSLLNADGLELIVTNLVKNFVG
FAPLGTVLVAMLGVAIAEHSGLLSAAMRGMVMGASKRMVTVTVVFAGIIS
NTASELGYVVLIPLAAMLFHSLGRHPLAGLAAAFAGVSGGYSANLLIGTV
DPLLSGITETAAKMIDPTYTVGPEVNWYFMFASTFVISFLGAFVTEKVVE
PKLGKYNVEEAAEDLSNDKMGSLTDVEKKGLKLAGVAVLVVSALLAWTIV
PADGVLRSDAGTVAGSPFLKSIVAFIFVFFAIPGFVYGKVVGTMKNDRDV
IDAMSKSMSSMGMYIVLVFFAAQFVAFFKWTNFGQVFAVAGADFLQTIGL
TGPMLFFAFILMCGFINLMIGSASAQWAVTAPIFVPMLMLVGYAPETIQA
AYRIGDSVTNIITPMMSYFGLILAVATHYMKNMGIGTLISVMLPYSIVFM
VGWSLLFYVWVFVFGLPVGPGAATYYTP
>VV10666 Dihydrofolate reductase
MIISMIAAMAKQRIIGKDNQMPWHLPADFAWFKRCTMGKPIVMGRKTYDS
IGRPLPGRLNIVISRDESLVIEGVTMANSIAHALALAGDADEVMIIGGGS
IYAECLPKADKLYLTFIDATIDGDTQFPDWGEQWCESHREHYSADEKNRY
AMDFVILERVNC
>VV10284 Lipoate synthase
MSKPIQMEKGVKYRDADKMALIPVKNMPTEQKEVLRKPDWMKIKLPADSQ
RIQDIKSAMRKNNLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPF
CDVAHGRPLPPEAEEPTKLAKTIADMKLKYVVITSVDRDDLRDGGAKHFA
DCNREIRAQSPHIRIETLVPDFRGRMDVALEALKDNPPDVFNHNLETAPR
LYRKVRPGANYQWSLDLLKKFKEQHPDVPTKSGLMMGLGETKEEIVEVLK
DLRAHGVTMLTLGQYLAPSRHHLPVERYVPPAEFDELKEIALELGFTHAA
CGPFVRSSYHADMQAQGLEVK
>VV11120 Uncharacterized enzyme of heme biosynthesis
MTSKKNNEPNKPEETTSQPITSDASTPETSNTESTASVSADEPTVTPTTP
PPAAAAKKEDKKPSQKLSILAIIIALLGTGGVAFQLQQQNSQYQAQIAAL
QNQLQQTQSAMSTELNQVKQETVAKATEVTHKAEVVLAQQQKSIESLQLA
MADVKGRRPNDWLLAEADYLVKLAGRKLFLEHDVVSATSLMESADQRIAA
LNDPSLVPLRKAMAKDITDLKTIPLIDRDGLVLRLTALQQQVDQLPLANA
ILPEAKTVEKQQVSDDINNWQNNLMASLKAFSENFITFRTRDGNVIPLLS
PEQHFYLKENIKAKIETAIKAVYQEQGEVYTTSLTTAEAWSQAFFNQDNN
TVKEFTQSLKQLSEQKIQVQYPVKLQTQNQLADVIRERLRREVTSMTSTE
AQQ
>VV11173 Outer membrane cobalamin receptor protein
MQKSLLAIAMASLLTPVSYLHAQEVQTNDTVVVTANRFEQPLAEVIASTT
VISKQEIEETQAKSLLDVLKRVPGIEVSQSGGRGHSASVFIRGFNSNQVL
FLVDGVRINSAAGGISFNHIPVGIIERVEVIKGPGGALYGSDAIAGVINV
ITTSSESSEGSVVSLGAGSDAQKEANFSTTRAFANGGVLKLAGGFEETEG
FDIKDPETGLNYGYESQNLFASYSQAFNDEFSGSASVRWYDSLTEYDSGG
KNYGYSENLSITADVQYSGSRLSSTLRANQQAIENLDYSQAEGKDNAGTV
KKIALTNLQFLNQYLISEGITIGAGADWRKEKLDDDALSYGYPDKLAGES
RSTTGVYLSTDLQLGDLQVTGSVRNDKHDTYDNYRTWSLGTRYQITESHS
VRATFGTSFKAPSYSDLTNNPDLKPEEAMSREIGYTGEFALFTVDVAAYD
NDVDNLIIWYEGSPWWYPENVDATLKGLEITGYFNTWFVHHTVVAEFKDH
QDSGGNKLAKRADENYKWLMDASYENFDVNLTYTYTGERLGNPKEVSDPK
NELPSVSLWDASVGYWISPDLVVRARVDNLTNEKYQTTLSYNAPERRYFA
NLTYQF
>VV11621 Dephospho-CoA kinase
MDRDSVDEQQVRAILKAQASRHERLALADDVIKNESKDQDLLQQITDLHQ
KYLAMSKQNR
>VV10321 GTP cyclohydrolase II
MPISTPQEIIEDIRLGKMVILMDDEDRENEGDLIMAAEHITPEAINFMAK
YGRGLICLTMTKERCQRLGLPPMVQDNNAQYTTNFTVSIEAAEGVTTGIS
AADRARTVQAAVAKEAKAADLVQPGHIFPLAAQDGGVLTRAGHTEAGCDL
ARLAGFEPASVIVEILNDDGTMARRPDLEVFAEQHGLKLGTIADLIEYRN
NTETTIERVAECKLPTEFGEFDLVTYRDTIDNQIHFALRKGTMGDQTPLV
RVHLQDTFTDLLRSDRNAERSWTLDKAMKRIGQEGGVLVILGNEESPELL
IHRVKMFEAQDKEEAPKLAKKQGTSRRVGVGSQILADLGVHDMRLLSSSN
KKYHALGGFGLNVVEYVCE
>VV21426 3,4-dihydroxy-2-butanone 4-phosphate synthase
MNQSSLLAEFGDPITRVENALLALKEGRGVLLLDDEDRENEGDIIYSVEH
LTNAQMALMIRECSGIVCLCLTDEHANKLELPPMVVNNNSANQTAFTVSI
EAKQGVTTGVSAQDRVTTIKTAANPSAKADDLARPGHVFPLRARPGGVLA
RRGHTEGTVDLMQMAGLQPAGVLCELTNPDGTMAKTPEIIAFGKQHNMPV
LTIEDMVMYRNQYDLKLA
>VV10187 Protoheme ferro-lyase
MSPPFRKTTFSHYRRESMNNTKKRGVLLVNLGTPEEATAPAVKRFLSQFL
HDQRVVDMTRWLWCPILHGIILPIRSPKVAKLYQTVWMKEGSPLMVYSKR
QQVELQAKLNCPVEIGMTYGTPSVLDGVNKLQAQGVDEICVLPLYPQYSG
TTTGAAYDALAHALRKVAVVPSIQFIRDYHDHPLYIKALAESVRQSWQVQ
GKGDYLLCSYHGIPQRYADNGDVYPLHCEMTTELLRLELGLDKSQIGTTY
QSRFGREEWLQPYTDKTLESLPAKGIKSLDVITPAFSVDCLETLEEISEQ
GQESFLHAGGEQYRFIPCLNDAPSHIEMMARLVTER
>VV11643 Ketopantoate hydroxymethyltransferase
MKKITINDLIKWKQEGRKFATSTAYDASFAQLFESQEMPVLLVGDSLGMV
LQGKNDTLPVTVEDIAYHTRCVRAGSPNCLLMADMPFMSYATPEQACENA
AQLMRAGANMVKIEGGDWLVDTVKMLTERAVPVCAHLGLTPQSVNIFGGY
KVQGRDQEKADRMVKDALALQAAGAQIVLLECVPAELAARITQVLDVPVI
GIGAGNVTDGQILVMHDMFGISANYMPKFSKNFLAETGDMRKAVALYMEQ
VQAGTFPDEAHTIA
>VV11353 1,4-dihydroxy-2-naphthoate octaprenyltransferase
MNQSLRIWLDAARPKTLPLALVSILTGSVLAYSFGQFSPVIALLSFVTAT
LLQILSNLANDYGDAVKGTDNDKRLGPMRAMQSGAVSAQAMKRAIVFNII
LTMISGLCLVFYALSSLQSILAFIGLGVLAIFAAIAYTMGSKPYGYVGLG
DLSVFIFFGLLGVSGTYFLHTGHLDTALLLPSLGCGLLAVAVLNINNMRD
IENDAACGKRTVAVRLGQQRAKQYHFALLGGALMAFASYLLLQPSSIWLC
LPFLFSLIVLFNHGKAVWQTEKPAQIAPMMPVVVKCSLVTNILFATVVVA
QTLVS
>VV10648 Thiamine pyrophosphate-requiring enzymes ; COG0028
MTAMLSGAEMVVQSLIEENVEQIFGYPGGSVLDIYDALHAKTEQIKHVLV
RHEQAATHMADGYARATGKPGVVLVCSGPGATNTITGIATAYMDSIPMIV
ISGNVPNSLIGNDAFQECDIVGVSRPVVKHSFLVKRAEDIPETIKKAFYI
ATTGRPGPVVIDLPKDVMNPLIKLPYEYPKSISMRSYKPTTSGHKGQIKK
ALKALLEAKKPVLYIGGGAIISGAHESILKLAETLNLPVVSTLMGLGAFP
GTHKNALGMLGMHGKYEANMAMHNADLIFGVGVRFDDRTTNNLEKYCPNA
KIMHIDIDPSSISKNVKVDLPIVGSAEQVLETMVTLLEEQGAENDTQALA
SWWDEIEGWKARDCLAYDTSSERIKPQQVIETLHKLTNGDAYVASDVGQH
QMFAALYYPFNKPRRWINSGGLGTMGFGLPAGMGVKFAMPEEEVVVVTGD
GSIQMNIQELSTAMQYDIPVKIINLNNRFLGMVKQWQDIIYQGRHSNSYM
SSVPDFAAIAEAYGHVGIRIETPDQLESELKRALDMKDRLVFVDINVDET
EHVYPMQIKGEGMDKMWLSKTERT
>VV11558 Aspartate oxidase
MNANREHECDVLVVGSGAAGLSLALRVANHCKVIVLSKGPRSEGATYYAQ
GGIAAVFDESDSIESHVQDTLIAGDGICEEATVKFIAENAKECVQWLIDG
GVPFDREEDDSDDEPRYHLTREGGHSHRRILHAADATGMAMQTSLQDNAH
NHPNIHVLERHNALDLITEDKIGGDKNKVIGAYVWNRNQEHVETVKAKFV
VLATGGASKVYQYTSNPDVSSGDGIAIAWRAGCRVANMEFNQFHPTCLYH
PEARNFLLTEALRGEGAYLRRPDGSRFMPDFDPREELAPRDVVARAIDFE
MKRLGADCMYLDISHKPAEFITKHFPMIHSRLMDLGIDMTKEPIPIVPAA
HYTCGGVMVDTNGQTDLHNLYAIGEVSYTGLHGANRMASNSLLECVVYAW
AAAKDILKKHKQVDLASSLPSWDESQVTCSDEEVIIQHNWHELRLFMWDY
MGIVRTDKRLERALRRIQMLQQETHEYYSNFRVSNNLLELRNLLQVAELM
VRCAMQRKESRGLHYTLDYPEQLENSGPTILRPEE
>VV13086 Molybdenum cofactor biosynthesis protein C
MSQFTHINASGEANMVDVSAKAETVREARAEAFVHMAPETLQLIVSGQHH
KGDVFATARIAGIQAAKKTWDLIPLCHPLLLSKVEVQLQAIEAENKVRIE
SVCKLAGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLEKTGG
KSGHFKVEA
>VV21599 NAD synthase
MEQLIRDEMRVLPTIDPHFEIERRVAFIKKKLVESGCKSLVLGISGGVDS
TTCGRLAQVAVDQLNQESNSNDYQFVAVRLPYGEQKDEEEAQLALSFIQP
THSVSVNIKAGVDGLHAASHIALEGTGLIPQDAAKVDFVKGNVKARARMV
AQYEIAGYVGGLVLGTDHSAENITGFYTKFGDGACDLAPLFGLSKRQVRL
VAETLGAPELLVKKVPTADLEELAPQKADEDALNLTYEQIDDFLEGKPVS
EAVSARLVSIYKATQHKRQPIPTIYD
>VV11552 2-polyprenyl-6-methoxyphenol hydroxylase
MTQYDVVIAGGAMAGATLALALSHLTDNKLNVAVVEPYQVDTSHPGFDSR
SIALSYGTVDILRRFQLWSSIAPCATPITDIHVSDRSHLAMTDISAQQVG
VDALGYVVELADVGRIYQSLLQRCESISLYTPAAVERVERFTDSVAVHLN
NGETLQAKLLVAADGAVSNCCQQLGMPLAQHDFEQTAVIANVVTEQAHRG
RAFERFTEHGPVALLPMSDNRMSLVWCLPPDLAEQVMLLSEEQFLARLQQ
EFGWRLGQMQKVGMRASYPLILRHREQNISHRFAVVGNAAQTLHPIAGQG
FNLGIRDVASLAEEITKQLDDVGAYSSLMRFKQRRCGDRQNTIWMTTSLV
HLFSNDYLALRVARNLGLVMMDNLSGLKQPLLRQTLGLVSR
>VV11119 Uncharacterized enzyme of heme biosynthesis
MIRLIFLFVVLGAGLFVGTQFSGQQGYVLISIANTTIEMSVTTLVIFIVA
ALAGLFGLEYLVKKVLYTGFTTWNWFSVRKMRRSRRYTNEGIIKLLEGDW
KGAEKKVTRWANHHDMPLLCYLVASEAADGQGDKAKRDHYLALAAEQENA
YLAVELTRSKQLVREGEFALAFDSLQSLKGRYPNNPIVLNLLKTTYLELK
LWQPLIDLLPTLNKQALISPEDAEQMHQRAQCGLLADVAGQQGSEGLIKH
WNTLPRKVKQDPHLVACFAKQLIARKADHEALTVIKEALKKSPSPELYAL
LPQLNLSDVHPVIVMLEQNVKNDNHNAEAHSALAQLYFREGKWPQAQSHF
ETALKVRSSVSDYAFLADALEKQNLNKAAHEVSRKALTLVQNH
>VV11536 S-adenosylmethionine synthetase
MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGM
VMVGGEITTSAWVDIEELTRETVREIGYVHSDMGFDANSCAVLNTIGKQS
PDINQGVDKADPKEQGAGDQGIMFGYACNETEVLMPAPITYAHRLMERQA
KVRKDGTLPWLRPDAKSQVTFQYEQGKIVGIDAVVLSTQHCDSISTPDLR
EAVMEEIIKPVLPSEWLNKETKYFINPTGRFVIGGPMGDCGLTGRKIIVD
TYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGMADRCEIQLS
YAIGVADPTSIMVETFGTEKVSHDIIIEAVRQFFDLRPYGLQEMLNLLQP
IYKKTAAYGHFGREEFPWEATDKAALLREFAGIK
>VV13065 Anthranilate/para-aminobenzoate synthase component II
MADIVFIDNFDSFTYNLVDQFRSLGHQVKIYRNSIATDTIVDAIEQLERP
VVLLSPGPGAPSEAGCMPELIARVKGKVPVIGICLGHQAIVEAYGGTVAG
AGEIIHGKVSMMEHQSHAIYQGLPSPLAIARYHSLVATHVPQTLTVTAEV
NGLVMSVVNEEDKVCGFQFHPESIMTTQGATLLANAINWALA
>VV11802 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MRELDTPASDSYNQRFGGTRRLYGNSEVEILRAAHVCVIGIGGVGSWAVE
ALARTGIGELTLIDMDDVCVTNINRQIHAMTGTVGQSKIEVMAERVKLIN
PECKVNLIDDFITPDNQHEYLSKEFDYVLDAIDSVKAKASLLAYCRSNKI
KVITVGGAGGQVDPTQIQVTDLTKTIQDPLAKKIKDTLRRHHNFPKNPAR
KFGIDCVFSTEQLKYPQADGSVCNVKSTAEGPKRMDCASGFGAATVVTAT
FGFVAVARIVEKLIQKHKN
>VV11627 Nicotinate-nucleotide pyrophosphorylase
MKNTHNSQERLDYLKQQLPIEITRAVTDTLKEDLGGSLNADNDVTAALIP
AEAINTATIITREHGVFCGQAWADEVFKQLGGKVTIEWHVKDGDKVEPNQ
TLCTLIGPARDLLTGERNAMNFIQTLSGCATITAQYAAKIAHTECRLLDT
RKTIPGLRSALKYAVACGGGYNHRIGVFDAYLIKENHIIACGGITQAVTK
AKELQPGKPVEVETENLDELREAINAGADIIMLDNFTTEMMRQAVEINAG
RAALENSGNVTLETIAEYAETGVDYISVGALTKHVKAMDLSMRFK
>VV13173 Isochorismate synthase
MYEVVLSHFHQAITNLIERVKNAKDDETRLVELLTTKPTLTFIDWLEAQP
VFPKFYWQSRDTREEVVALGQLHTFVDPGPAYTILSPGQRVWGGRSFDGS
SEKNRRCMPSFFFLPQIELIRLDDKWSLAVNLNGDKSRILHTLSKLTTEA
KPLAPLTAHIQSVEHLPEREGWCDLVSKVLKGIQAKAFKKVVLARKTTVH
LDSALCAAQLLKASYLQNHHSFHFMLSLDSKHSFIGSTPERLYLRQGQEL
YTEALAGTIGRGHNATQDMELASWLSQDVKNLNENQYVVDDIVDRLTPHA
ASVEVESEARLVRLRKVQHLKRNIHAQLKAGVNGVQLLSALQPTAAVAGL
PRQESMQFIVENEPFARGWYAGSVGYISHEQAEFCVAIRSALIVDDSLHL
FAGAGIVPGSIAEHEWSELDKKMSTLLSLISEHPPLGVAS
>VV11199 Biotin-(acetyl-CoA carboxylase) ligase
MGLNMQMQADCHSIDQPCTALSQIEFGARLDRTELALTLMAKWREALSEY
EQCGLNGFIERWNRLDNFKGRQVKLLIGPREIHGEVQGIDSQGGVILKTV
EGIQTFVGGEISLRANDQ
>VV12576 ABC-type tungstate transport system, permease component
MNKVALTLAATSITLVSFSSFSADDVHRVRLATTTSTYHSGLLDYLLPEF
EKDTGYKVDVLAAGTGKSLKMGENGDVDLVMTHAPKAEATFVEKGYGVLP
RKLMYNDFIVVGPKADPAKVAQDNSVLEVFKAIADNNVTFISRGDDSGTH
KKELGIWAQTKMEPNFGGYRSVGQGMGPTLNMASEMQGYTLTDRGTWLAY
NNKLDLAVLFEGDQKLFNPYQVILVNPERYPSINYQGAKAFSDWLVNPRG
QELINSFRLNGKQLFVANADQK
>VV11198 Biotin-(acetyl-CoA carboxylase) ligase
MRKEHVVKLHLLKRLADGQFHSGETLGHELGISRAAISKHINALQDWGVD
VYRIQGRGYQLAQPMTLLDEHQLVEQSANNVEVIPVIDSTNQYLLERIEN
LQTGHVCLAEYQSQGRGRRGRQWFSPFGSNLYMSMYWRLDAGMAAAMGLS
LVVGIAAVEALETLGVQGVKLKWPNDVYYQDKKLAGNFGLDDWPSRRRCS
SW
>VV20367 Uroporphyrinogen-III methylase
MTLTSLSSLQNQGFVSLVGAGPGDPDLLTVKGYRVIQQAEVVVYDRLVSP
EILALANEKAEMIYVGKKLDFHCVPQEEINQILVRKALEGKRVVRLKGGD
SFIFGRGGEELEELAEHDVRFEVVPGITAAAGATAYAGIPLTHRDHAQSV
QFITGHIQKDGKEIEWPSLAQANNTLVFYMGLKQCRYIAEKLLENGLDAS
TSCAIIENGTRREQRVLTGTLTQLPELATQAISPALIVVGSVTSLHDKLK
WF
>VV21204 Glutathione synthase
MHICFLMYPWDRVCPETDTTLRLIHECALRGHTVAITTTSGLTIRDSNVF
GFCQVLKKGLRISDKVPTFYRQAEFQKACLPMAGFDVIFMRANPPLDNLA
LNFLDSIKDDTLIINDLEGLRIANNKLYTASMGGTASEFLPSTHVSKNRE
YLQRVLEESQSEKMILKPLNGFGGHGVIVIEKNAQQNFRSLLDFYIGEGE
QSNYVILQDYIEGAEEGDKRILMLNGEPIGAMARIPAKGEFRSNVHAGGS
VIKHTLTKEERRLCAAIGPKLVRDGLYFTGLDVIGNKLVEVNVLSPGGIT
RINKLNRVRLQRQVIDFVENIVNSKELLQQRKSAFRTAVQNAHIDP
>VV10559 Cobalamin biosynthesis protein
MTELFDQLYANGALLILWGALLFHLIIPIPRSSHPVTLWHKFAQLLADKV
NTQQSYQQSLISGHLALLLMLFPCLAVLFALKPLVWQPQLFELALLLLAL
DWRSNESLAKALIRAMANEDKAAARSLLAPYLNRETTTLSQLGIGKAAAE
TLIMGYGRNVVGVLFWFALSGGIGALMYRLTIELARAWSPSRANYAPFGV
ATVRFAAVLDFIPLRLFAVMILLGQHTGQTWQGMRQQVASWPLPGPAWLL
CAVGNKLQLSLGGPAIYQGKRAERAKIGGRIAPSALHIDQLQHLLARRIL
VWILLQSLLMGLIYQGI
>VV12702 Uroporphyrinogen-III methylase
MDLENKPVLVVGGGEVASRKIEALLNVGAKVTIVSPTLVDELHRWVEENR
CYWVKNFYSSELMDGAYVQVWATTNNPSLNHQVYRDAKQRNLLVNVVDDK
PYCDFITPSMISRGRVQIAISSGGASPVLIRNLRESLEAVLPQNLSLLAE
FAESKRVAVKERFPTVEERRMFWELFFDLPEVKSSQNHRELETLFAQAIK
GELQRTAQCTWIGCTEDVELLPIKALRYMQKAELVLAPEQIHPAFLEMVR
RDAQRLSYETPAQLSEKIQQAKLEPIKICVLFAKNSQEFSFLQQGDLII
>VV10705 3-polyprenyl-4-hydroxybenzoate decarboxylase
MSMTNQEKSITLAFTGASGAPYGLRLLQQLLAADYRVYLLISSAARVVLA
TEHGLKLPANPDAAQQALVKHLGCPADKLVVCGKDDWFSPVASGSAAPKQ
MVVCPCSAGSVAAIAHGMSDNLIERAADVVMKERGQLILVVRETPFSTLH
LENMHKLSQLGVTIMPAAPGFYHQPQSIDDLIDFMVARILDHLGIEQVLV
PRWGYDHRNDGDSV
>VV20283 S-adenosylhomocysteine hydrolase
MDFEAFNVLFWRVFPSIKAGAEYFHVQPATVRRWLSGSIPINPMAEKLVI
IKSLGYLPNDIRWRGFRIDEARAVLITPSGREFSPKELEAFAYQKDEYQH
FLEQYERPQSPKYYPAKENILPFKGGRRMTAAPWIPSKLK
>VV10909 Ubiquinone/menaquinone biosynthesis methlytransferase UbiE
MTDISVQSNTALESSETTHFGFTTVAKEEKVAKVAQVFHSVAAKYDIMND
LMSGGIHRLWKRFTIDCSGARPGQRVLDLGGGTGDLTAKFSRIVGEKGHV
ILADINNSMLNVGRDKLRDSGIVGNVHYVQANAEELPFPDDYFDIITISF
CLRNVTDKDKALRSMFRVLKPGGRLLVLEFSKPVFDPLSKVYDAYSFHLL
PKMGELVANDADSYRYLAESIRMHPDQETLKGMMQEAGFENTSYYNLTGG
IVALHRGYKF
>VV20397 Uroporphyrinogen-III methylase
MDTSISTQLRDRSYSEHAISYHSSRRLQAKNRPTSTGMAASGFVYLVGAG
PGDPEMLTVKAVNALQQCDLLVYDRLVSKEILALVPEHVDKIYVGKRCGE
PSLKQDEINQILVSFAQLGRKIVRLKGGDPFIFGRGGEEALALVEHNIHY
CVVPGITAAIGCAASCAIPLTHREVARSVTLVTGTVVTGSLPAWSAIVEA
GQTLVFYMGLESARAIEQGLLGQGVRADFPVAIVTQGSTPEQKTYVTTLA
TLEKTAVALKGVSPALIIMGEVVKLRERLKTTLAAVAPMANASFVNE
>VV12150 Conserved hypothetical protein
MKLRRKGIMGMNKRNHAYIGRYNDRSKYPLVDDKLKTKIIAQRAGCTVPQ
LIGVISNQADVKRIHEMVKDWPGFVIKPARGSGGKGILVVTSHKEGVYTK
PSGSTINKEEIERHISNALAGLFSLGGKNDVAVVENLIKFDNCFDGFSFE
GVPDVRIIVFKGYPVMAMMRCSTAASDGKANLHQGAVGVGIDIATGKAIR
AVQFNQPVTHHPDTGKDLATLQVPHWQRLLTLAASAWEMTGLGYLGTDMV
LDKEEGPMVLELNARPGLAIQIANGAGLLPRLHHIENLGAPLVYPSAEER
VAYSMRQFGAKQDFDSSAS
>VV12944 Adenosylmethionine-8-amino-7-oxononanoateaminotr ansferase
MDLAFDRQHIWHPYTSTLTPLTCYPVNSASGVYIKLEDGTTLIDGMSSWW
STIHGYNHPHLNRAAHHQIDQVSHVMFGGITHQPAINLCKKLLSLAPNNL
EHVFLADSGSVAVEVSLKMALQYWHARGERRPKFLTLQHGYHGDTFAAMS
VTDPDNSMHSLYKGFLPEHIFAKSPTGGFWDEWKPEDLTDFAQKIEQHHQ
ELAAVILEPIVQGAGGMRIYHPEFLKGVRALCDKYGLLLIADEIATGFGR
TGKLFACEHADIQPDILCVGKARLGAT
>VV11568 Pyridoxal phosphate biosynthesis protein
MSSIYLGVNIDHVATLRNARGTKYPDPVHAAEVAERAGADGITIHLREDR
RHITDRDVRILRETLQTRMNLEMAVTDEMIEIALKTQPEYVCLVPEKREE
LTTEGGLDVAGHLDKIKAATEKLTAAGIKVSLFIDADREQIDAAKACGAP
FIELHTGHYADAATEADQLDELKKIAAGASYAADLGITVNAGHGLTYHNV
APIAALPEIYELNIGHAIIGRAVFDGLHKAVADMKAIMVAARQ
>VV20908 Molybdenum cofactor biosynthesis enzyme
MTEVCNYSCKYCFAKWGRPKELHRSEQAIDNLLDKLADYFIKGTPVLKEK
LGYESVRLNFAGGEPMMLGNTFVTALVLAKQKGFKTSTITNGHYLIHGKS
PLPKDTLDMIGISFDSQYLSTRMKIGRNDRKGNSFGVNDLTHALARLTQS
QTGIKTKINTVINSLNWEEDFTNLISSLNPYKWKVLQVMPYGDNELLISK
EQFDNFVHRHSGLGLPIYFESNSTMTESYLMISPEGCFYQNTANKSGYKY
SECINSCGVEKALSQIEFNPITFASRYKKTNIDIVDVS
>VV21659 Lipoate-protein ligase A
MGVRNIVATKNRLIRYLSIDAETLFQREEALIKQVQAGELDQVLLLWQVK
HPTLVLPAGNKWPQTEHLRAELAKLGWKLTARKTGGAPVPQVPGIINLSH
LYHWPQDQAYDIRSAYLKLCETLCGFFQQYGLEADVHATPGSYCDGDYNL
NIAGQKIVGTAQRVLLKKSGGQIILAQACLLIDADMAEIVKPVQLCNQLS
NHNAEILADVHTPLYQHIEQRPSIDRLFQSLSDAFVKQVKS
>VV11200 Panthothenate kinase
MSPFLSFSRATWSELRNSVPMTLSEEDLKALQGINENLTMQEAVEVYLPL
SRLLNLYVQARQSRNSVLHQFLNNDEHAPPFVIGIAGSVAVGKSTTARVL
CALLSRWENHPKVELVTTDGFLYPKKELDQRGIMHKKGFPESYDMKKLVQ
FVSDVKAGKPELEVPVYSHITYDITEEVKKVDRPDVLIIEGLNVLQSGMD
YPHDPHRVFVSDFLDFSIYVDAESNTIEQWYVERFLKFRKGAFTQPGSYF
SHYTQLSEQQAIEKAQQIWRDINGINLTENILPTKERAQLILRKGPNHLV
EEILLRK
>VV13005 Branched-chain amino acid aminotransferase
MYWVNGVVATEVSLSDRSFQYGDGCFTTMKTLNGQIEHWPLHIERMEACL
QVLSIPLPDWALVEQWLHQAALPDARGGLKLHISRGEGGRGYSPSGVATP
NVTISSFSYPVHYSQWQQHGVELGVCQTPLGINPILAGHKHNNRLEQVLC
KGELDALGYLDGVTINVQNHVIETTIANLFWVKNGVLFTPDLTLSGVSGV
MRRLVMGEAQRRAIACQEIKADLSSLLAAEEVFMTNSLLGVAPINQILET
RYPIGTTTRYFEGIFNS
>VV13087 Molybdenum cofactor biosynthesis protein B
MGHAESKFQPANIAVLTVSDTRTEENDTSGAYLVENAKEAGHNVVDKQIV
IDDMYKIRAIVSQWIADENVQAIMITGGTGFTSRDSTPEALKPLFDKEVE
GFGELFRLVSYEEIGTSTIQSRAIAGFANHTVIFAMPGSTGACRTGWTKI
IKQQLDASHRPCNFMPHLSV
>VV11810 2-dehydropantoate 2-reductase
MNILILGPGAVGSLWATKLKLAGHNVALWGRGDASEQPLQLDDSSAMTFK
HRHLPSLQSADLILVTVKAWQVMAAIEPLLPHIHSDTIILLMHNGMGTAS
QVEEQLTHNPIVVATTTHGAYKPHSQQVLHTGQGITQLGGFNTQGAQCEF
LQVVLDHALPSVTWNPNIQQALWTKLAINCAINPLTAIHQCKNGELADER
FHQRLERITQELVDVMVKEGIEVTFDTLQQTIMNVIHATAENYSSMRQDV
FHQRRTEIDYITGYLLQAAHKHQIDAAENAKLYQHIKQIEQSWTEQ
>VV10935 3-polyprenyl-4-hydroxybenzoate decarboxylase
MSFKDLRDFLNHLEKKGQLKRITHPVDPAYEMTEISDRTLRAGGPALLFE
NPIGYDIPVLTNLFGTAERVAMGMGREQVKELREVGQWLAYLKEPEPPKG
FKDALDKLPVFKQVLNMPVKRLRKAACQEVVWQGEEVDLDKIPVMSCWQD
DVAPLLTWGLTITRGPNKKRQNLGIYRQQKIAKNKIIMRWLAHRGGALDL
RDWMEKYPGKPFPVSVAFGADPATILGAVTPVPDTLSEYAFAGLLRGSKT
EVVKSVSNDLEIPASAEIVLEGYIDPNEYADEGPYGDHTGYYNEKEKHHV
FTITHITMRKEPIYHSTYTGRPPDEPAVLGVALNEVFVPILQKQFPEIED
FYLPPEGCSYRMAVVTMKKQYPGHAKRVMMGVWSFLRQFMYTKYVVVCDE
SVNARDWDDVVKAMTENMNPILDSLFIESTPIDSLDFASPVAGLGSKMGL
DATIKWEAELALQGATVSTEFASQIGIDVNALKAVHPLISDIYVPAVASG
QFMVVKINKTHAGQCKEVVESLWQVESVKQRNKFIVVCDDDVKADDWHDI
IWAITTRMDPARDTLKIDGSESCSAKLVFDATNKYPEEITREWGKPIKKD
PKLVAKVDALWQEFGIL
>VV10254 Glutamyl-tRNA reductase
MSLLAIGINHHTASVDLREKVAFGPDKLANALQQLSQHEAVNGSVILSTC
NRTEVYCDVKSGARSKVIDWLSQFHQIGLEELKPSLYVYEEQAAIRHLMR
VSCGLDSLVLGEPQILGQVKQAYSDSREQQAVDASLEKLFQKTFSVAKRV
RTETDIGGNAVSVAYAACTLAKHIFESLEKSTVLLVGAGETIELVAKHLH
ANGCSKMIVANRTRERALTLAEQFDAQVISLQEIPNHLAKADIVISSTAS
PLPIIGKGMVETALKQRRHQPMLLVDIAVPRDVEAQVGDLNDAYLYTVDD
LQSIIDSNIEQRKVEAIQAEAIVAEESAAFMSWLRSLQAVDSIREYRQSA
NEIREDLLSKALLSLESGSDPEKVLRELSNRLTNKLIHAPTRALQLAAEQ
GEPAKLTVIRQSLGLDELK
>VV12257 6-pyruvoyl tetrahydrobiopterin synthase
MFEAAHHLPHVPEGHKCGRLHGHSFLVRLYVEGEVDPHTGWVVDFAEIKA
AFKPIYNRLDHYYLNDIKGLENPTSEVLAKWIWQQLKPNLPLLSKVEIKE
TCTAGCIYKGE
>VV20835 Isochorismate synthase
MKREVIGYTKMANELLDNELSSSPFFFASPNNTMMGIGVQEERLQTLPFS
ELADVANNMLKNAKTSESDNPVLFGVVPFNQENMTRFVIPKTLYISSSTR
ASHTSASSAPQARLISSPSGHHYKQGVHDLLGMFANQELSKVVLSRAIEV
ATETDIQQQALLRNLLSINAKGYTFAAQIGDNQKLMGASPELLVAKKGSH
LISNPLAGSRPRSESEQQNQASIQSLLNTGKDLHEHGLVVEEVERVMSKY
CCNLYTPMVPSVIETQTMLHLSTQLEGQVLDPAINVLQVAAELHPTPAVC
GYPREKAYEAIKRLEQFDRGYFTGMVGWCDSRGNGEWVVTIRCAEVQPRR
MKVFAGAGIVNESQPQSELDETGAKMNTILKAAGIQLNEMLTA
>VV12787 Cobalamin-5-phosphate synthase
MKTWQYQYQLFCLAVSFFSRLPVPKSTPYSDERMNQAGRYFALVGTLLGL
LCVLVYAFASLFFPYQVAIVLMMAFSLLLTGAFHEDGLTDMADGIGGGMT
LDKRLTIMKDSRIGTYGSATLTMALIGKFVFLTTLARQPDFGLMIVVAYT
LSRAVAATLIYDMPYVSDSDTSKSKPLANAQSSTELAILILTGVLAAISL
GLGVGLLLILFAILFRWAFKRWLLARLGGFTGDCLGGAQQLMELGIYLVL
IAVVQ
>VV10283 Lipoate-protein ligase B
MQNQLVVKRLGRRDYLPVWQAMHEFTDTRNEETPDEVWLVEHNPVFTQGQ
AGKAEHLLNTGDIPVVQSDRGGQVTYHGPGQLVAYFLINLRRKKLGVRDL
VTTIENLVINTLKAYNIDSAARPDAPGVYVEGRKICSLGLRIRKGCSFHG
LALNVNMDLSPFLRINPCGYQGMEMVQVSELGGPKDIALVEQQLVKELVN
LLGYEQVEFSTEAEVREA
>VV21034 Dihydrofolate reductase
MSNIVYIATSLDGYIAGPNNEMDWLHQVPNPDGSDFGFADFMASVDALVM
GRNTFEMVLSFGVEWPYNKPVFVLSNTLKSVPEGYQDKVFLVQGALPTMV
AQLHQQGYQRLYIDGGKTVQSFLAEDLIDEMIITTIPVLLGAGIPLFGRL
PKALNFKHIHAERLADHMVKNHYVRVR
>VV11553 2-polyprenyl-6-methoxyphenol hydroxylase
MIQSVDVAIVGGGMVGLALAAAFKDSDLRVAVIEGQAPNLQMNELPDVRV
SALSRSSEHILKNLGAWQSIVEKRASPYVAMEVWDQDSFGHIDFSADAMA
QPDLGHIVENRVIQLALLEQVNKLDNVMVLMPCQCQSMSVGESEVWLSLD
NGQALTAKLVVGADGANSWVRRQQDIPLTHWDYGHSAIVANVRTVEPHGS
VARQIFTPQGPLAFLPMSEENMTSIVWSTESLRATSLMAMSDREFNKALS
AEFDMRLGLCEVVGERFSVPLKMRFARDFVKERVALIGDAAHTIHPLAGQ
GVNLGLLDAASLAQEILALWQRGEDIGTKRNLRRFERWRKAEAAQMIAAM
QGFRELFAGSNPLKKFLRGVGLTMAGHLPGAKEQIMRRALGLDGELPELA
KRRQPELIRS
>VV10265 2-polyprenyl-6-methoxyphenol hydroxylase
MFRKLASKTYNAKPSLNQVDQEYKMNKYDIAVVGGGMVGAAVAIGFAKQS
RKVIVVEGFEPKAFEASQPMDIRVSAISHNSVRLLESLGAWQHIQATRVC
PYKRLETWEHPECRTRFHSDELNLEQLGYIVENRLIQLGLWQEFAQYPNL
TLQCPDKLKRLEFDEFNTLTLESGLEIEASWVIGADGANSQVRELAGIGI
TAWDYRQHCMLINIATESAQQAITWQQFTPSGPRSFLPLKGQQGSLVWYD
SPKRIRELSAMSAEKLKQEIIRHFPDELGEFDVLYWDSFPLTRRHAQAYY
QQNCLLLGDAAHTINPLAGQGVNLGFKDVEALLKATENQPLTVAQQAAYQ
KARYADNLLMQTGMDLFYKGFSNDITPLKLVRNAALKLAEHSGPIKHQVL
KYALGM
>VV21433 Hydroxymethylpyrimidine/phosphomethylpyrimidinek inase
MLLTSTTQSLIPCVLTIAGSDSGGGAGIQADIKTISATGSYASSVITAIT
AQNTMGVNAVFPIPTECVAAQLDAVFSDLNIQAVKIGMLADRHIIRLVAE
KIRQYAPEKVVLDPVMISTSGHALLQPDAIAALKEHLIPLADIVTPNIPE
YVALTGMPIPNTENEMISSVESLKALNCPAILLKGGHLQNESHSSDLLIT
PQFCEFIRSKRHSTRNTHGTGCTLSSAIASYLAQGHRLHKAVFLAKQYIS
QAIAHADELSVGQGHGPVNHFFAGHMHVR
>VV21600 Nicotinic acid mononucleotide adenylyltransferase
MLKIAVFGSAFNPPSLGHLSVIESLSHFDLVLLEPSIAHAWGKEMLDYSV
RCELLDAFIQDLTLSTAKRSNIEQELYQPGESVTTYALLTRIQEIYPEAD
ITFVIGPDNFFKFANFYQAEEITQKWAVMACPEKVQIRSTDIRHAIDCGD
DLAELTTPSVRKLLIERQLYKTIP
>VV20543 GTP cyclohydrolase I
MSGLSESAQLVKQALEKRGLETPMVPNQFSREEKKEKIEHHMREILSLLE
LDLTDDSLEETPRRIAKMYVDEVFSGLDYQNFPKITVIENKMNVSEMVRV
KEITLTSTCEHHLVTIDGKAAVAYIPRGKIIGLSKINRIVRFFAQRPQVQ
ERMTQQILVALQTLLESDDVAVTIDATHYCVKSRGVMDATSETTTTALGG
IFKSNPATRAEFLHGLR
>VV10959 Thiamine biosynthesis enzyme ThiH
MSFVEHFNQLNWDDIRLSIYSKTALDVERALSKNKLDLEDFKALISPAAE
HYLEAMAQRSYALTRKRFGNTLSLYIPLYLSNLCANACTYCGFSMENRLK
RRTLTVQEIYAEMAAIKAMKFDSVLLVTGEHEGKVGMNYFRQVLPQIKRA
FNYLAMEVQPLSQEHYQELKLLGLDAVMVYQETYHPATYAQHHLRGNKTN
FNYRLETPDRLARAGIDKIGIGALIGLEEWRTDCFYVAAHLDYLERTYWQ
TRYSISFPRLRPCAGALQPKSVMSDKQLVQLICAYRLFNPEVELSLSTRE
SALFRDNVLPLGITSMSAASKTQPGGYAMPDVELEQFEISDERSAAEVEQ
MIRSKGFDPVWRDWHAAYSGARFS
>VV11030 Branched-chain amino acid aminotransferase
MATKTADYIWFNGKMVPWAEANVHVLTHAMHYGTSVFEGVRCYNTPKGPI
VFRHQEHAQRLKDSAKIYRFPIPFSVEEIMEATRETLRQNKLDNAYIRPL
AFVGNVGLGVCPPTDTEMDLIIAAFPWGSYLGEEALENGVDAMVSSWNRA
APNTIPTAAKAGGNYLSSLLVGGEARRHGYAEGIALSVDGYLSEGAGENI
FVIKNGVITTPPATAAILPGITRDSIMTLAREMGYEVREANIAREALYLA
DEVFMTGTAAEVVPVRSVDQIQVGAGKRGPITKAVQEAYFGLFNGTTEDK
WGWLDYVYPEKK
>VV10347 Putative p-aminobenzoyl-glutamate transporter
MDRFLNFIERVGNKIPDPAILFFWALVITWAASALLSNVSFDLINPRTGD
ALAIKNLLTGESLASFLANMVTTFTGFAPSRDRVSGDAWCRCCGLFRLYY
HRP
>VV20545 Dinucleotide-utilizing enzymes
MLRYNRQIILRQFDFEGQEALKQSSILILGAGGLGCAASQYLATAGVGKL
TLIDDDIVELSNLQRQVLHHDADIGRKKVESAAQSLRELNPHIEVVTVAQ
RLSDSELETLIKNHSLVLDASDNVETRNQLNRLCFATKTPLVSGAAIRME
GQVSVFTYQNANEPCYQCLSALFGSNALSCVEAGVMAPVVGIIGAVQAME
AIKVLAHFGTPKSGKILILDAMTMSWREMNLMKLPACPVCNDDSQRTSQT
>VV11827 Thiamin biosynthesis lipoprotein ApbE
MKKWLVAFASLLVLAGCEKPAEQVHLSGPTMGTTYNIKYITQEGLPKPDV
LQQEIDRLLEEVNDQMSTYRKTSELSRFNQSRDSAPFAVSQQTATVVKEA
IRLNHLTLGALDVTVGPLVNLWGFGPEARRDVVPSAEDLAERKAQTGIEH
LSVVDNTLIKTLPNLYVDLSTIAKGWGVDVVADYIQSQGVQNYMVEIGGE
IRLKGVNREGVPWRIAIEKPSVEERAIQDIIEPGDMAIATSGDYRNYFER
DGIRYSHIINPKTGMPINHKVVSVTVLDKSSMTADGLATGLMVLGEEKGI
EIANQNSIPVLMIVKTDDGFTEIASDAYKPYLKNQ
>VV10662 Pyridoxal phosphate biosynthesis protein
MVKRLVVTAGEPAGIGPDLVLALSKEHWPHQLVVCADKKMLAQRAEQLGI
NVTLLDYDASTAPSPQQAGTLVVEHIDMPSTCVAGQLNEENGHYVLKTLE
RAALGCMKSEFDAIVTGPVHKGVINRAGVAFSGHTEFFAELSNTPLVVMM
LATEGLRVALVTTHIPLAYVSKAVTAERLLKIIDILHRDLVEKFAIAEPK
IYVCGLNPHAGEDGCLGREEIETITPTLEKIRQEKGIHLLGPLPADTIFN
EKYLNDADAVLGMYHDQVLPVLKYKGFGQSVNITLGLPFIRTSVDHGTAL
DLAGTGQADTGSFRTALQHAIELVEKKQ
>VV12942 8-amino-7-oxononanoate synthase
MTQAFNERIAQALKQRREQGLSRQSEVIFSGNQTVLEHQGKRYLNFSAND
YLGLANDQSLVRAWQQGLSLYGCGSGASPLVTGYTPAHSNLAASLCDWLG
YESATLFGSGFSANQALLFALLEKGDLLVQDKLNHASLIEAGLLSPATMK
RFKHNDLKALDTILNRSDCPSLVVTEGVFSMDGDCSPLAEMHALTQRHSA
SLMVDDAHGVGVLGEEGRGSCALASVKPDFLVVTFGKAFGLSGAALLTDK
SSGDFLAQFARHHVYSTALPPAQAFALTHAVEMIRTQQWRRDKLNELQTL
FAEYLGEHDSFVATQTPIKPWLIGETQQAVMVAQRCREQGIWLTAIRPPT
VPQNTARLRITLSANHTKEQMHTLAQVLLTVTGEH
>VV13088 Molybdenum cofactor biosynthesis protein A
MAQQFEDRFHRKFYYLRLSVTDVCNFKCTYCLPDGYQPSGQKNSSFLNLS
EIRRVVKAFADCGTSKVRITGGEPSLRKDFTDIIHTVASTQGIKRVATTT
NGYRMEKHIGEWKEAGLNQINVSVDSLDPRMFHQITGENKFHQVMSGIDR
AFEVGFEQVKVNVVLMKDLNHNELPAFLHWIKHRPIQLRFIELMQTGEMD
TLFQQHHVSGVAIRNHLIANGWLLKVKAANDGPAQVFVHPDYQGEIGLIM
PYEKDFCASCNRLRVSAKGKLHLCLFGDRGVELRDLLQQDDQESDLIARI
QSELQTKSVSHFLNEGQTGMTPHLASIGG
>VV11312 Anthranilate/para-aminobenzoate synthase component II
MENGSLPACFELTAWTTHADGSMDEIMGYQHKTLAIDAVQFHPESIKTEQ
GHQLLANFLAR
>VV11404 3'-Phosphoadenosine 5'-phosphosulfate sulfotransferase
MLDSVASTLQLSELLSLTKAEQSIRLAEINVELEMLSAQERVAWALQNLE
GAHAVSSSFGIQAAVMLHLVSKQQADIPVILTDTGYLFPETYQFIDELTK
SLNLNLKVYRANESANWQEARYGKLWEQGIEGIEKYNKLNKVEPMRRALN
ELNVKTWFSGLRREQSQSRAGLPILSIQNGVFKFLPVVDWSNKDVHYYLK
EHGLSYHPLWEQGYLSVGDTHTTQKWEPGMSEEETRFFGLKRECGLHEED
NEQDGSGI
>VV10726 Sulfate adenylate transferase, subunit 2
MDQQRLTHLKQLEAESIHIIREVAAEFDNPVMMYSIGKDSSVMLHLARKA
FYPGKIPFPLLHVDTDWKFREMIEFRDRTAEKYGFELLVHKNPEGLAMGC
SPFTHGSSKHTDIMKTQGLKQALNKYGFDAAFGGARRDEEKSRAKERVYS
FRDKNHTWDPKNQRPELWKTYNGQVNKGESIRVFPLSNWTELDIWQYIYL
ENIEIVPLYLAAKRPVVERDGMLIMVDDDRMKLKEGEVIEEKSVRFRTLG
CYPLTGAIESEANTLTGIIEEMLVATSSERQGRAIDHDQSGSMELKKRQG
YF
>VV20180 S-adenosylhomocysteine hydrolase
MCTVSYTAVIVRKEVQMTAVDRIYQKIKRSRRYVFERKDFDGFASYDQIG
RALRQLVQQGELMKLGYGLYTKARINSLTGKPMPTNPGGTDALVREILKM
KGVDFEMDSLSQQSLSGASTQIPSSVHYSWNPKQFNRKLVVGSRVLNLPS
>VV13085 Molybdenum cofactor biosynthesis protein D
MIKVLFFAQTRELVGVDSVDVEANFDTVESLRAHLAEQEGKWSLALEAGK
LLAAVNQSIVPLETTLQDGDEVAFFPPVTGG
>VV13170 Dihydroxynaphthoic acid synthase
MGTTMAKTVGITEAELYAPVNWNDCSAPYEDIQYHKSEDGIAKITIARPQ
VRNAFRPQTVKEMIQALADARYDSNVGVIILTGLGEDAFCSGGDQKIRGD
YGGYKDDSGVHHLNVLDFQRDIRTCPKPVIASVAGWAVGGGHVLHMMCDL
TIAAENAQFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRFYDAQ
EALDMGLVNTVVPVEELEKETVRWCREVLQHSPMALRCLKAALNADCDGQ
AGLQELAGNATMMFYMTDEGQEGRNAFNEKRRPDFNKFPRNP
>VV10727 Uroporphyrinogen-III methylase
MSMADKDTATVFPFKRPSVVASNPTAGRYGHSQLKHGEVALVGAGPGDPE
LLTLKALNYLQQAEVVLYDYLVSDEIMALVPNDAILVCVGKRAGHHSVPQ
EKTNQLLVDFAKQGYKVVRIKGGDPFVFGRGGEELEVLADAGITFQVVPG
ITAAAGATAYAGIPLTHRDYAQSAMFITGHLKAESDQLDWSTLARGQQTL
VIYMGLMKSNYIQEQLIKHGRRAQTPIAIIERGTQLSQKVFKGQLSELAD
LAKKAEAPALIVIGEVVQLSQKLDWFLSGTRINNSAIANSI
>VV12372 Nicotinate phosphoribosyltransferase
MCAPLFQPAIIQSVLDLDVYKINMMQAAYRFYPQTQVRYELIVRSDDNLS
DLVEEVREEINRLAELRFDAAQLAYLAEKAPYLTAEFLSYLETFRFHPQQ
QVSVGIFRTAQGDCQLRVTINGIWHETILYETLVMSIISELRNRRYWAQI
PQSQLHKVLEDKLDFLDSELKRRNITNFRFSEMGTRRRFSFAAQKTMLDV
LRARVPELLLGTSNYHLAQEFNLTPIGTVAHEWTMAHQALVAIQHSQRVA
LDKWLEAFNGSLGIALTDTIGIDAFLSDFDLDKATAYAGVRHDSGSPFVW
GDKIIAHYESLGIDPTTKTLIFTDGLDFARALDICEYFAGRAQISFGIGT
FLANDMGNWTNDKGTRYQPISMVVKMAECNGSPVAKISDEPEKAMCEDIF
FLMNLKQRFGLEVDLDKAIETLKQMKRQQKKRIQSVA
>VV11644 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokin ase
MITAYIAIGSNLADPVSQAKSAIDALKTLPKSRLLVASQLYSSSPMGPQD
QPDYINAVAAIETELTPLELLDCTQAIELEQGRVRKEERWGPRTLDLDII
LYGDEVIDSERLTIPHYGMKEREFVLYPLAEIAPNLTLPDGTELSQLLTI
VDKNGLGIWHS
>VV11546 Phosphoglycerate dehydrogenase
MAKVSLEKEKIKILLLEGLHPSSVEVLQAAGYTNIEYHKGSLSDDALLEA
VKDAHFIGIRSRTNLTEEVINAAQKLVAIGCFCIGTNQVDLNAASKRGIP
VFNAPFSNTRSVAELVLGQILLLLRGIPEKNALAHRGIWKKSADNSYEAR
GKRLGIIGYGHIGTQLGIIAENLGMRVYFYDIENKLSLGNATQIPTMSEL
LNKCDVISLHVPETPETKNMMGAEEFARMKPGSIFINAARGTVVDIEALC
HSLESGHIAGAAIDVFPVEPATNAEPFESPLQKFDNVILTPHVGGSTQEA
QENIGVEVAGKLAKYSDNGSTLSSVNFPEVSLPEHRSCSRLLHIHQNRPG
ILTQINTIFAEEGINIAGQYLQTSADIGYVVIDVETERSEEALVKLKEIE
GTIRARILH
>VV12234 GTP cyclohydrolase II
MAEVRARVDFKVGAKSNIDAEILSFRGLKTDKEHVAVIFKSADVTQEVPL
VRMHSECLTGDVFHSSRCDCGEQLEETINRMGESGGIILYLRQEGRGIGL
YNKIDAYRLQSEGMNTYEANNHLGFDDDLRDFTEAAQMLEALGIKQIRLV
TNNPKKIRELSEYGIEIVEVVNTSAHIKEGNESYLKAKVSHGKHHLKV
>VV12945 Adenosylmethionine-8-amino-7-oxononanoateaminotr ansferase
MTLSATLTSKHVADTVCGGEAGCFMHGPTFMGNPLACAVATASLELIEQG
QWQQQTKQIESLFSELLPKLEEYDLVKNTRWLGAIGVVETHRPVNMETVQ
ALFVEQGVWIRPFGKLIYMMPPFISEPAHIEQLVNAIETALQRAECFV
>VV10314 Geranylgeranyl pyrophosphate synthase
MDNSMIDVLASFQQRNNQQLNLWLDKLPHQNQALIQAMRYGLVLGGKRAR
PFLVYATGEMLGCSQEQLDTPASAIECIHAYSLIHDDLPAMDDDELRRGQ
PTCHVKFDEATAILTGDALQTLAFTILAEGTLSADGETQRVAMIQALAQA
SGAQGMCIGQALDLAAENRAVTLEELEEIHRNKTGALIRCAVRLGALAAG
EKGLAILPQLEKYSTAIGLAFQVQDDILDIISDTETLGKPQGSDQELNKS
TYPSLLGLEGAMEKAHTLLHEALQALEAIPYNTQHLEEFARYVVERKN
>VV11530 Glutathione synthase
MIKLGIVMDPISSINIKKDSSFAMMLEAQRRGWEIHYMEMNDLHLDQGIA
IADTKVVQLKEDPNGWYEFTSEQTIELAELDAVLMRKDPPFDTEYIYATY
ILERAEEQGTLIVNKPQSLRDCNEKLFTAWFPELTPTTIVTRKAEKIKAF
RQEHGDIILKPLDGMGGASIFRVKENDPNVSVIIETLTNHGQNYAMAQTF
VPDISNGDKRILVVDGEPMPYCLARIPAKGETRGNLAAGGSGEPRPLSET
DLKIANAVAPTLKEKGLIFVGLDVIGDKLTEINVTSPTCIREIEAAFDIS
ITGKLMDAIERRLQAQA
>VV10978 Protoporphyrinogen oxidase
MIVKALFLYSSREGQTKKILQYIEEQLPSYQCDVKNLHDIDTVDFSVYDK
VLIGASIRYGHLNQKLYQFIQHNLTQLNEHKVAFFCVNLTARKEEQGKDT
PEGSAYIRTFLKKSPWQPNLIGVFAGALYYPRYNWFDRNMIKLIMTLTGG
ETDTSKEVEYTNWKKVRQFSEKFACL
>VV10323 Pyrimidine reductase, riboflavin biosynthesis
MSEFTAIDRQMMLRAIALAKRGLYTTAPNPNVGCVLLRDGEIVGEGFHFR
AGEPHAEVHAMRMAGDKAKGATAYVTLEPCSHYGRTPPCAEGLIKAGVSR
VVCAMEDPNPQVAGRGFAMLREAGIEVSVGLLQAEAEALNPAFIKRMKMG
MPFVQLKMAASLDGQTALANGKSQWITSPQARRDVQRFRAQSGAILSTSK
TVLADNASLNVRWSELPSSVQRALPQEQLRQPTRVVLDRQAELSPELKLY
QTEGERLIVGPKGDLPAPLDEHGQIDLPQLFAQLSQTQLINHLWVEAGAT
LAAGLIKHQLVDELIVYLAPKLMGSDGRGLMGALGLQAMSQVIDLDIKDV
RMVGPDIRIIAHIKAKES
>VV11121 Uroporphyrinogen-III synthase
MAVLVTRPAEQGQALCQLLQQAGVPALQHPLIDIVANSSLNTLANDLKQS
DVIIAVSQHAVQCAEHILKAQQQNWPQNALYLAVGQKTAHYLSKVTHQDV
NYPTVSDSEHLLQLPVFNRIAGKRVLILRGNGGRELIHQALSQRGADVRY
CETYQRELIPFDAVSSLTLWRDQGVDTLIVTSAEQLDYLHAQMSDEGKFW
LYQQRLLVPSERIAAIATQLGFTQVCNVGSASNKDLLAALQPK
>VV11311 Anthranilate/para-aminobenzoate synthase component II
MLLIIDNYDSFTYNLYQYFCELGAQVQVVRNDEIDLAGIAQLNPTHLVIS
PGPCTPNEAGISLAAIEHFAGKLPILGVCLGHQAIAQVFGAKVVRARQVM
HGKTSPITHNGRSVFKGLNNPLTVTRYHSLGWKMARYQRVLSSPHGQLMP
MAAWTKSWAISTKHWRLMRFSFTQSRSKLSKDISY
>VV11843 Coenzyme F390 synthetase
MNKQTMMENLSELNTKGLDANSLMQQALEAEKSRNFAASKVGNVTVGLSS
GTSGMRGLFLADKQETQLWAGNILGRLLPSLWGKHRIALALRANSPLYKS
VAKGPITFFYADLNKPYQEWIKELDEFQPTLLVGSAQALQLCAQFSGQFG
QPAIQPKRIISGAEVLTEIDRHYISQKFDSELHEVYQCTEGFLACTDQQG
QMRWNQDIVYIEKHWLNAERTHYSPIITDFRRKTQPIIRYQLDDIIESKQ
DNGVFEPLGAIAGRCGDCLKLNASQVAVSVLPDLIYRSITLEIQDRVDYR
ITQTGAQAIQIEADVHHHPAIYRALVKLFDQLRLDPVTFNYRPAPIWTPM
NKQRRVVNTCGF
>VV10701 ABC-type thiamine transport system, ATPase component
MLTLQQVHYYYHQDLFAFDLEVEAGSIVALMGPSGAGKSTLLALLAGFIA
PQSGQMALDGRLLNTLSPAQRPFSMLFQEHNLFAHLTVRDNIALGLHPGL
KLTSQQQKQVEQAAKQVGIEAYLDRLPEQLSGGQRQRVALARCFVQPNPI
WLLDEPFSALDPVLRDEMLSLVKQLAQERAITVLMVTHHLSDARAIASHF
AYIDKGTIAAHGPIASLNEKHSHPELVEFFQAAV
>VV11218 Uroporphyrinogen-III decarboxylase
MTELKNDRYLRALLKEPVDCTPVWMMRQAGRYLPEYKATRAQAGDFMSLC
KNAELASEVTLQPLRRFPLDAAILFSDILTIPDAMGLGLRFSTGEGPIFD
NPITCKADVEKIGVPDPEGELQYVMNAVRQIRKDLNGDVPLIGFSGSPWT
LATYMVEGGSSKAFTKIKKMMYAEPQTLHLLLDKLADSVIEYLNAQIKAG
AQSVMVFDTWGGVLTPRDYNLFSLQYMHKIVDGLIRENDGRRVPVTLFTK
NGGMWLEQIAATGCDAVGLDWTINIADAKARVGDKVALQGNMDPSMLYAS
HDRIREEVASILEGFGHGGTGHVFNLGHGIHLDVPPENAGVFVEAVHELS
KPYHQ
>VV10964 Thiamine biosynthesis protein ThiC
MSNRKQARLEAKQFIDTLSVQPYPNSTKVYVEGSRSDIRVPMREISLADS
LVGGTKEAPIFQPNEAVRVYDTSGVYTDPTHQIDLYNGLPKLREEWIAER
ADTEVLDDVSSVYTKERLEDETLDELRYGNLPRIRRAKAGYCVTQLHYAR
KGIITPEMEYIALRENMGRAKYQDEVLTQQHAGQSFGANLPKEITPEFVR
REVAEGRAIIPSNINHPESEPMIIGRNFLVKVNANIGNSSVTSSIEEEVE
KLVWSTRWGGDTVMDLSTGRNIHETREWILRNSPVPIGTVPMYQALEKVN
GVAENLTWEVMRDTLIEQAEQGVDYFTIHAGLLLRYIPMTAKRVTGIVSR
GGSIIAKWCLAHHQESFLYTHFREICEICAKYDVALSLGDGLRPGSIADA
NDEAQFAELRTLGELTKIAWEYDVQVIIEGPGHVPMHMIKENMDEQLKHC
HEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGCAMLCYVTPKEHLGL
PNKEDVKTGLITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWQDQFN
LSLDPDTARAFHDETLPQESGKVAHFCSMCGPKFCSMKISQEVREYAKGQ
QGEAGQAIEVKLLDDPLEGMKQKSAEFKASGSELYHPAVSHEEVAEG
>VV12781 ABC-type cobalamin transport system, ATPase component
MYVAGPNGSGKSTLLSAIAGTLSSREGVKGEVLINETSLLTLPLAEQAIY
RAYLCQQSRPAFNVDVFQMLALSLPVGRHVAEPEVQAAVRRVVELVQMQD
KLHRSVQALSGGEWQRVRLAAVCLQVWRSLNPYSQLLILDEPAAPLDVAQ
AKWLYQLIDEMAAQGLVVIVANHDLNRVYQHADKVLLLNQGVLTAYGSAD
EVMSVENLQQVFETPVKKVAVDGQPYLIFT
>VV12415 Probable riboflavin biosynthesis protein RibD
MSEEHMLRALEVSKFALPNCLPNPPVGCVLVKEGSIVAEGFTQKIGGNHA
EVQALEAYSGDMDSVTAYVTLEPCSFIGRTPACAATLVKSGIKHVVVSIL
DPDPRNGGRGIQILEQAGVQVDIGLCSSQVSAFLEPYLGKS
>VV21011 ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component
MYQLVDASFEIDDKVILSPTNLTFASGKVTTLLGHNGCGKSTLVKLLSRQ
NAPTQGQVLFNQQPIASFNSLEFAHQVAYLPQHPPITDGVTVRELVYFGR
YPWKGAFGRYGKEDYAIVDEAIEKVGLTAFAQRFVATLSGGERQRAWVAM
LLAQQSQCILLDEPTSALDVAHQHELLALIRELNQTMGLTVIMVLHDVNM
AAKFSDHLIALHSGKVIAEGNPQALMTPETLMKIYGMELALFAHPKTGKP
ISYIP
>VV10960 Thiazole biosynthesis protein ThiG
MLKIADKQFHSRLFTGTGKFANSQLMSQAIEQSGSQLATMALKRVDIHNQ
QDDILSPLLSAGVNLLPNTSGAKNAKDAIFAAHLAREALGTNWLKLEIHP
DPKYLMPDPIETLAAAEQLVKDGFVVLPYCHADPVLCKRLEEVGCAAVMP
LGAPIGSNKGLVSQDFLQIIIDQAKVPVVVDAGIGAPSHAAYAMELGADA
VLVNTAIAAARDPIAMARAFKLAVEAGRLAYESGLAGKVSHAVASSPLTS
FLDECLS
>VV10346 Putative p-aminobenzoyl-glutamate transporter
MLVAMLGVGVADSSGFITTGLKKMLNFTPAKLLTPMLILVAIVSHTAADA
GYVLVIPLGGIIFHAAGRHPLAGIAAAFAGVSGGFSANFIPSGIDPLLAG
FTQTAAQVLDPAYVVNPLANIFFTGLSSVIIIAIGWYVTEKIIEPRLAST
PIDDDAEKAPDLGSFTELESKAFRYAGWAMMAGIALLIAAIWPENSALRS
PNGEITAFSAPIMKSIVPLIFILFIIPGYVYGRVSGTFKSSNDIIKAMAT
TMSTMGAYIVMSFFCAQFLSAFAQSNIGTMLALYGAEGLKAMNLPGEATI
VGMILLTASVNLLIGSASAKWALIGPILVPMLMAVGISPELSQAAYRVGD
SVSNIISPLMVFFPLVVVYCQRYVKSTGIGTLASLMMPFSIAMLIGWTIF
LLAYWAVGIPLGVQAPYTYTM
>VV20306 Quinolinate synthase
MIKSSKEFRKLVVETEDAFKRGSLNGAFIVLDEIQQSILSPVRAVKLCTL
IERVIKNRWGTLRFEDAANLKTNLKMRLKLIEQRNRNQIRKQEEAPEALA
VDGAESSHAVKKILRCDHHIHTDLIIKAGEQVEVIEKYPADSLVSHPKCK
GFFAWNDQLEDLNSPRGGLRELGERVQ