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# Rhodoferax ferrireducens DSM 15236, DSM 15236

>Rfer_1281 Shikimate/quinate 5-dehydrogenase
MAVWTLGINHTTAPLDLRGRFAFALDQVEPTLRALRGSLSRQPEAALIST
CNRTEIYCAGEKPELEHTLDWLAQTGGVSSSLLRTHSYTLQDDLAARHAF
RVASGLDSMVLGETQILGQIKNAVRAAEAAGALGNTLSQLFQRSFAVAKE
VRSSTEIGAHSISMAAAAVRLAGQLFEDLGQVKILFVGAGEMIELCATHF
AAKSPKAIAIANRSLENGEKLASRFGAEVMRLADLPDRLHEFDAVVSCTA
STLPIIGLGAVERALKRRKRRPMFMVDLAVPRDIEIEVKALEDVYLYTVD
DLASVVQTAQASRQAAVAQAEAIVDAGVLSFMHWVDQRGSVPLIQQLNAQ
ADEWRAAELARARKLLAKGEDVEAVLEALSKGLTQKMLHGAMTELRASDT
AARERASAAIQHFFLRKER
>Rfer_0132 Carboxylyase-related protein
MAYRDLRDFITQLEHLGELKRVQAEVSPYLEMTALCDRTLRAGGPALLFE
NPTGHNTPVLGNLFGTTRRVALGMGVNDVSELRQFGHVLASLKEPEAPKG
FKELMGLGSLVKTLWAMAPKELRSAPCQEIIWEGADVDLARLPIQHCWPG
DVAPLITWGLVITQGPHKARQNLGIYRQQVLARNKVIMRWLAQRGGALDF
KEHAALNPGQPYPVCVALGADPATILGAVTPVPDSLSEYQFAGLLRGSRT
ELVKALGSELRVPAFAEIVLEGHIYPDATHASGFEHALEGPFGDHTGYYN
EQDWFPVFTIDRITQRRDPIYHSTYTGKPPDEPAMLALALNELFVPLLQR
QYPEITDFYLPPEGCSYRLAVVQIKKSYPGHARRVMFGIWSFLRQFMYTK
FIVVVDDDVNIRDWKDVIWAITTRVDPTRDTLLADSTPIDYLDFASPVSG
LGSKMGLDATNKWPGETSREWGRPLTMSADVTARVEQVWQTLGL
>Rfer_2889 molybdopterin binding domain
MSASASSPFDPIKIGIVSVSDRASGGIYVDKGLPALQAWLTRALKNPLQF
EPRLIPDEQATISATLIELVDAGCALVLTTGGTGPALRDVTPEATLAVAH
KEMPGFGEQMRRISLQFVPTAILSRQVAVIRNQTLIINLPGQPKAIAETL
EGLRGGDGALVMAGIFTAVPYCIDLIGGPYLETDEAVCKAFRPKAAIRTF
S
>Rfer_3880 Methionine adenosyltransferase
MANDFLFTSESVSEGHPDKVADQISDAILDAIFKQDPKSRVAAETLCNTG
LVVLAGEITTNAHVDYIQVARDTLKRIGYDNTEYGIDYKGCAVLVAYDKQ
SNDIAQGVDHASDDHLNTGAGDQGLMFGYACNETPELMPAPIYYAHRLVE
RQAQLRKDGRLPFLRPDAKSQITMHYVDGKPHSIDTVVLSSQHSPEMSNG
LTMKPAFIEAVMEDIIKPVCPKEWLTADTKYLINPTGRFVVGGPQGDCGL
TGRKIIVDTYGGACPHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLA
RQCQIQVAYAIGVAKPMNVTVYTEGTGVIPDDKIAELVHELFDLRPKGII
QMLDLLRPIYEKTAAYGHFGREEPEFTWERTDKAQALRAAAGL
>Rfer_0373 aminotransferase class-III
MKMNDVQTLATPRLDAAWLDAHWMPFSGNREFKANPRMMASAKGCYYTDS
HGKQIFDGLSGLWCCGLGHGRNEITEAVTQQMATMDYSPAFQFGHPLSFA
LANKLKELTPAGLDYVFFTGSGSESADTSLKMARAYWRAKGQATKTRLIG
REKGYHGVNFGGVSVGGIGGVRKMFGQGIEADHLPHTQLAGNAFSRGMPD
KGAELADDLLNLIALHDASNIAAVIVEPFSGSAGVIIPPKGYLQRLREIC
TANNILLIFDEVITGFGRAGAYTGAEAFGVTPDIMNLAKQISNGAQPIGA
VLAKKEIYDTFMAAGGPDYMLEFAHGYTYSAHPVTCAAALATLDILVKEN
MIDRVKALAPHFENAVHSLKGVRHITDIRNYGLAAGFTIDALPGEPAKRP
FEIAMAMLKKGFYVRYGGDTIQLAPPFISTPAQIDSLVNALGETINQTA
>Rfer_2828 ubiquinone biosynthesis O-methyltransferase
MSHQPYFADNHPMTSTLNADPAELAKFSDLAHRWWDLEGEFRPLHQINPL
RLEWINHLCPVAGQQVLDVGCGGGILADSMARLGAQVTGIDLASKALRVA
QLHALEAQTPNLQYQEISVEALAAQQPGSFDVVTCMEMLEHVPDPASVVR
ACATLVKPGGWVFFSTLNRSPKSFVLAIVGAEYVLNLLPRGTHEYAKMIR
PSELASYCRSVELDLRHTRGMQYNPLTRRYWMSDDTSVNYLFATQKSNAA
IL
>Rfer_1319 quinolinate synthetase complex, A subunit
MTNTTDTVKEVDYEQPQRETAAGAAVCATKHAWARVPAEPAPAERAALKD
KIRRLLREKNAVMVSHYYVHPDLQDLAEETGGLVSDSLEMARFGRDHTAQ
TLVVSGVRFMGETAKILSPEKRVLMPDLDATCSLDLGCPVDEFSAFCDAH
PDRTVVVYANTSAAVKARADWLVTSSCALEIVSALKDKGHKILWAPDRHL
GGYIQRETGADMLMWGGSCIVHDEFKAFELKALMKEHPAARVLVHPESPA
DVVALADAVGSTSAILKAAHEMEAQEFIVATDSGMMHKLRTLNPGKLFLE
APTAGNSATCKSCAHCPWMAMNCLADVARVLETGANEVHVDPALGLRARI
PIDRMLAFTAALKGGRDAGSLVPLIGAA
>Rfer_0676 putative CapK protein
MSLYTALCSNFFFPLHERLKGHDSVALRKHLEESQWWPAEQLETYRAKRL
QQFLVDIGQRVPYYQQLFKQLNFVPNTVRSTAALQLLPLLAKSDIRKNVD
KLKAEGHGPLTRYNTGGSSGEPLIFYMGKGRKSHDVAAKWRATRWWGVDI
GDPELVVWGSPMEIGAQDRVRRLRDALLRSRLLPAFEMSPQNLDRFVETI
RVTRPTMLFGYPSSLSLIAQHARHKSVAMNSLGIKVAFVTSEKLYEEQRA
IISEVFACPVANGYGARDAGFIAHQCPEGSLHISAEDIIVETVRPDGSPA
AAGEAGEIVVTHMATVDFPFVRYRTGDIGVLDDKPCACGRGLPVLKEVQG
RTTDFVVARDGTIMHGLALIYTVRDLPGVERFKIEQLSLDQTIVKVVAGP
AFGAAAEARIIRDFKARLGEAVDIRVERVRDIANESSGKFRYVVSQVRVF
GNGKEVKSA
>Rfer_1774 molybdenum-pterin binding domain
MSIQAINVRNQFRGKVKEIIHGDVVSEVDVETPWGIVTSVITSRSVKDLD
LKVGSEVVALVKSTEVSIAKL
>Rfer_3934 lipoic acid synthetase
MSHSPDDLATPAIPASVREVQPPEAYDPLVKQKSAAKLSRIPIKVVPGEI
LRKPAWIRVKAGSPTTRFYEIKDVLRSNKLVTVCEEASCPNIGECFGKGT
ATFMIMGDKCTRRCPFCDVGHGRPDPLDVNEPANLATTIAQLKLKYVVIT
SVDRDDLRDGGAGHFVACIQAIRDKSPQTQIEVLVPDFRGRDDRALEILK
AAPPDVMNHNLETIPRLYKEARPGSDYQFSLNLLKKFKALFPDVPTKSGL
MVGLGETDEEILAVMRDMRAHGINMLTLGQYLAPSSSHLTVKRYVHPDTF
KMFEAEAYAMGFSHAAVGAMVRSSYHADQQAGHALSQL
>Rfer_3314 Anthranilate synthase component I and chorismate binding protein
MRAFIDFPASLPAAPGGVQSARWSARFEAPLQVLTAWQLHEVPAVLQQVQ
QQARAGRWCVGELAYEAASAFDAALVTQQACPDWPLARFAVFDRPFPESQ
TASPPPVAPSAGAAPHPMPEWTLASDFADYATRFERARQAMADGECYQVN
LTEALRARWPAADTRDIAAWFERLRAAQPGGYQAWLDWGEQQVLSLSPEL
FFDWRPDGAEGVLTCQPMKGTAPRHADPRLDAQACSQLRESAKEQAENVM
IVDLLRNDMGRIAQPGSVQVSRLFAVQALPTVWQMTSTVCARTRPGVGLP
ELFAAMFPCGSVTGAPKARAMHWIAALERGPRGVYCGAVGVVRPGGAATF
NVPIRTVALQRGSVAPGPPAAPAWHGHFGVGSAITFYAEPLAEWRELAAK
TRFLARAAQRFELLETLRLEAGHYWLLEQHLARMAGSAAYFGFEWRPADV
QACLDQLLGGREQGVYRVRLTCSSEGQVQAQAFDLQPSPQPVFFNLSAQA
LESMGREHEFVTHKTTRRQHYETRLRSAPGVFDTLMRNERGELTEFTRGN
LALKMAGRWRTPALHCGLLAGTYRADLLARGDLTEEVLTLADLQGAEEVA
FFNSVRGWLVARLVA
>Rfer_2985 Dihydrofolate reductase
MKLHLIFARSANGVIGLNGKLPWHLPEDLAHFKRTTLGSPVIMGRKTWDS
LPPKFRPLPGRLNVVVTRQPHWQAAGALTAHSLAEACALCPSDSHAWVIG
GAELYLQALPMASTAVVTEIDANFEGDAFAPQFGPQWRETARERLVSSTG
LSFSFVTYCRNTGV
>Rfer_3571 Glutamate--cysteine ligase, monofunctional
MLKFTCCDAVKQFSEHAAAPLLRGITRGYERECLRVDRSGTLAQTPHPLT
LGSKLTHPWITTDYSEALLEFITPPSQDPAFPLQFLRDIHRYSAQQLQGE
YLWAGSMPCVLSTDQAIPIADYGPSNAARFKYVYREGLGLRYGRQMQTIA
GAHYNWSLPADFWLALQDCCCAKNVGQAFVSERYFGLIRNFLRFGWLIPY
LFGASPAICESFLRGHPSDLPELVPGTRYGPYATSLRMSDLGYQNRAQAN
LHISVNSLAEYTQALEAAIRTPDPYYEQLGVRDGDHWKQLNANLLQTESE
YYAGIRPKRVGHDRPAKALQRDGVEYIEMRLFDLNPFIDIGIAPEQSTFA
DVLLLMCLFRDSPPITSREQSENDENKHRIVNYGRQPGLQLLVHNREQPF
RSLAHELFDDMQPFADMLDAAYGGQRYSSTMQGLRTRIDQPDSTPSAQVL
EAARTQGGFFNFGMQMARQHTQALQAQALDAATTAKFVASVKDSLQAQQK
IDAAEQGSFEAFVAQYFA
>Rfer_0731 putative ubiquinone biosynthesis monooxygenase COQ7
MPNTLQDRFFTTCDAALRTLFVTPHAERACPTLPGEATALTDAEKVQSGA
LMRVNHVGEVCAQALYTAQAFATKNEALRAHFTKASADETNHLAWTQQRL
DELGARPSLLNPLWYGAAFGLGLLAGRLGDPISLGFVVETENQVEAHLES
HLSLLPANDHASRAIVAQMKDDEVRHALDAQKAGAVPLPPPVKSLMTAAA
KVMTTVAHRI
>Rfer_1699 NAD+ synthetase
MTLKLCVAQLDFVVGDMAGNAKKIIESARSAYADGVRLLLTPELSICGYA
AEDLFLRAAFIAACDDAVKTVARELAGLKDMSVVVGHPTGGDSRTRSVAV
SRRHNAASVLREGAVIATYAKRELPNYQVFDERRYFTPGHDVCVFEAGEA
DKMGQKIKVGLLICEDAWFEAPARQTQAAGAELLVVINASPFHVGKGDER
EQMMRERVRACGLPLVYAHLVGGQDEVVFEGRSFALNANGEVAARAPSFI
QNELVIQVSRAYEAIYLAADIAPERSLDADLWDALVLGVRDYIGKNGFPS
VLLGLSGGIDSALVLAVAVDALGKDRVRTIMMPSPYTADISWIDARDMAA
RLGVRYDEISIVPEFEAFKKSLAGEFQGLAEDTTEENIQARIRGTLLMAL
SNKFGSIVLTTGNKSEMATGYCTLYGDMAGGFAVIKDLAKTTVFRLARWR
NEHDPYGTGQAPIPERIITRPPSAELRPNQTDQDSLPAYEVLDAILERYM
ENDQSIEEIIAAGFARLDVEKVTRLIKINEYKRRQAPVGIRVTHRSFGKD
WRYPISNKFRA
>Rfer_1576 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family
MTQPFDICIRGDGIVGRTLALLLARERLRVGLVARPAAMSPNAATTAPDV
RAYALNAKSRALLESLRCWPDARHATEVLAMRVLGDDGGEVNFSAQELKV
QGLTWIVDVPVLEAQLAAAVRFQPQIELLDAPQPASLTVICEGKASRTRA
EFGIEFEVARYPQTAIAARLACEAPHGQTARQWFTQGEILAFLPIDGPQG
NSVAIVWSVLDGRVDALLGASPVEFCRQLQVASYGCLGQLQLTSERCAWP
LQSARAERWVGIHEGKAWALAGDAAHNVHPLAGQGLNLGLSDVAALAQTI
HEREYWRSVGDEKLLRRYERARKAEVLTMGATMDGLQRLFSNSSAVFQAA
RNLGMNGFERSGPVKQWVARQAMGF
>Rfer_1243 3-demethylubiquinone-9 3-methyltransferase
MKESDIRPEALLNRYLEFSASDAERCFADVVRQPIPCVGCGGSQANHEFE
KNGFAYSSCTACGSLFQSPRPTLAAFEAFYRDSVSSRYWAEVFFPAVAEA
RRERIFKPRAERLSSLCAQKNVQVDKVIDVGAGYGILLDEWRALHPNASL
LAIEPSSVLANECRAKGLDVIEDIAENVTGYQSYADLVVCFEVLEHVYDP
LAFVRTLVNLARPGGYVFISTLGVDGFDIQLLWEKSNSIFPPHHINFLSV
AGFKLLFERAGLEEIDVTTPGVLDVNIVQNAVKKDPKILHNQRFVRTLLA
SDATAAAFQRFLSDNLLSSHTWVLGRKPL
>Rfer_0529 thiamine-monophosphate kinase
MGEFELIERYFKRPERHAARVALGIGDDCALLQPAPGTQLAISCDMLVEG
RHFVSTLDPFKLGHKALAVNLSDLAACGARPLAFSLALALPRADESWLAP
FAQGLLALADAHSCELIGGDTTQGPLNICITVFGEVPVMAGRSQALLRSG
AQAGDDLYISGNLGDARLALEVFRGTVSVPEAVFTAARVRLETPTPRVAL
GLALRGVANAAIDVSDGLLGDLGHILQQSGVGATVDADVATSLIAAHAYY
TGATGQFDTNIAPEQWRRWALSGGDDYELLFTAPVARREAVAAAAAASLT
PVTRIGQIEAERGLRLMDAQRQPVPDRYASFDHFA
>Rfer_2459 Sulfate adenylyltransferase
MNAPILSNLLQPMTHHPRPDHLSNAHLDALEEETIFILREVAAAFERPTL
LFSGGKDSLVMLKCAEKAFMDSKTGGHIPYPLLMIDTGHNFHEVTDFRDA
RAKELGAELIVRSVEDSMARGTVRLAHPGESRNVHQSVTLLEAIEEFRFD
ALIGGARRDEEKARAKERIFSHRDSFGQWQPKEQRPELWTLFNTRLHPGE
HFRVFPISNWTELDVWQYIARERVALPSLYYTHQRAVVERKGLLVPVTDL
TPAKPGEQVQTRNVRFRTVGDITCTCPVESRAATPDDIVIETLAADVSER
GATRMDDKTSEASMEKRKKDGYF
>Rfer_1087 5-formyltetrahydrofolate cyclo-ligase
MDTTDEKKAQAKKALRKRLVEQRLNLPDRLQRANLLQRVMRIWLVGRPDA
VIGAYWPIKGEFDPLPALHRWKEDGELIDQPQPRMIGLPVVDKVHKTMAF
HAWYPGCPMEEDAYGILKPKDTEVIVPTLLFVACVGYAAGGYRLGYGGGF
YDRMLAALTPQPFTVGLGFAQGFLPDFEPEPHDIPLDAILNDNGVVWPV
>Rfer_3779 periplasmic sensor signal transduction histidine kinase
MLSPVVVGGASFAYLLLLFAVAYLGDWRAAQGRSIIANPWTYALSMAVYC
TAWTYFGSVGRAASGGVWFLPIYLGPTLGMVLGWVVLRKMIRIAHAYRLT
SIADFIGSRYGKSPLLAGLVTLIAVVGIVPYIALQLKAVSAGYALLTTPQ
GADFAAQPHWGQDSTFYMALALAGFTMVFGARHLDSTERHEGMVAAIAFE
SVVKLVAFLAVGLFVVYGLFDGLTDLFARVQAVPALAGLLRLEQGGSFAW
TQWFALTLLSMLSLMFLPRQFQVMVVENVRESHLRRAVWVFPLYMLAINL
FVLPIALGGLLYFGPGQMNAETFVLSLPLAAGQNALALFAFIGGLSAATG
MVIVETIAVSTMVCNELVMPLLLRTRHFRRDAGRDLTRILLGIRRLAILG
VLVLGYVYFHLAGEAYALVSIGLISFAAVAQFAPSVLGGMYWKGGTRRGA
VAGLLAGFLMWAYTLMLPSIAKSGWLGDEFLYKGLGGLALLLPERLMGMQ
GLDNLTHSLFWSLLVNVAAYVGLSLWRAPSGPEASQALLFVDVFRRTASS
SPVFWRGQARVPDLLRLCERFMGVQKARALFRSYAGPVEARQMDTIRADA
RLVQFVETQLAGAVGSASARVLVASVVEEEPLTPEDVLRILDEASQLRAH
SRELEEKSDSLERATAELRQANEQLKSLDRLKDDFMSSVTHELRTPLTSI
RALAELLRDDPRIALAQRRQFIEIIVSETERLSRLVNQVLDMAKIESGHA
EWHTAEVDMRALVSQAVSTTAELFRERQIAVEVALPEQVPTLMADPDRLM
QVMLNLLSNAAKFVPLPGGRVRVSLSSDDSGVTVAVSDNGPGVAAEQQAL
IFDRFRQGGDAANRPQGTGLGLPISRQIVEHFGGRLWLESGLQQGARFLF
HLPRNNTSCAPDASATGDTA
>Rfer_2667 riboflavin synthase, alpha subunit
MTERLSEIQLFPCENTPMFTGIITGVGRIAAVHALGSSSSHGKRLSIECP
PAFLDDVGLGDSIALNGACMTVTALDVAGQQFCVDISAESLDKTAGLNAM
GTINLEKALRANDRLGGHMVSGHVDGIGTVTHFSQVGESWQLRVLAPKAL
AKYLAYKGSITVNGVSLTVNRVQDTEDGCEMSINLIPHTVQNTALNTLQT
GSLVNLEIDLIARYVERMLNADPQHTHLAAP
>Rfer_0883 extracellular solute-binding protein, family 1
MSQAFRSLPSTRGLLAAAAAIALTASSAASADTKTIYIGMNGGTMEKAYT
QYVFPAFEKANNVRVVVVPGTSSDILAKAQANKDKPQMHVMFLDDGIMVR
AIGMGLCQKQRPSPVLSEIYPAARFKDDMATGVSLGMTGLAYNTKMFKEK
GWAAPTSWMDLADPKFKGKVVFQSVSSSSFGLHGFLMFNRIQGGTDKNVE
PGFKAWPTMIGPNVLEYIPSSAKLSEMVQTGEAAIFPLTPTSVAALKVKG
IPVEYAQPKEGSVVLMVGQCVIANNSEPELAQKLTEFLLSPLAQANVLQF
GAQIPTNPKAPAVGDGVKQVADITKWMKTAVTLDWDSVNANRPTWNARWN
KTIER
>Rfer_1667 Coenzyme A biosynthesis protein
MANHVIAVYPGTFDPITLGHEDVVRRATQLFDRVIVAVAAGHHKKALFSL
EERMAMTREAVKHYPKVQVESFSGLLRDFVVSQGAKAMVRGLRAVTDFDY
EFQLAGMNRSLMPDVETVFLTPSDKYQFISSTFVREIASLGGEVDKFVSP
SVNECLIEKVRSLAQP
>Rfer_2470 Phosphomethylpyrimidine kinase
MITNIFKFEYPRVLSIAGSDSGGGAGIQADLKTFSALGCYGMTAITALTA
QNTCGVRAIHAVPPQMLRDQIDAVMEDIGADAVKIGMLHSPEIVQTVAQA
IDRHAMHHVVFDPVMVATSGAVLIDDAAIEVLVRELFGRAAVITPNLDEA
ALLVGYPLVSKQDMERAALDLLAKGARAVLLKGGHLPGHNVMDLLLSAGG
EKLWMEAPRIDSPNTHGTGCTLSSAIAAYLALGASLPDAVQQARNFVREA
LQAGAQVRTGKGSGPLNHGYAPIAMRPRKS
>Rfer_3605 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase
MKLLMIDNYDSFTYNIVQYLGELGADVTVARNDEITLEEIEARLSAGALD
RLVISPGPCSPTEAGISVAAIQHFAGRLPILGVCLGHQAIGAAFGGKIIR
AQQLMHGKTSLITTTQEGVFAGLPAQFTVNRYHSLSIERATCPPCLKITA
WTDDGEIMGIKHTSLDIEGVQFHPESILTEHGHAMLKNFLKPRGTDRSDA
KRTSSVPN
>Rfer_2619 ABC transporter related
MTSIAVHARAVRARLGNVEILHGVSLALPSGRWTSIVGPNGAGKSTLLKV
LAGLLPHQGSVELLGQPLASIRPKKRAQRLAWLGQNESTADDLTVWDVAM
LGRLPHQAWLAAPSEADRAAVEQALKATQAWDWRGRTLGQLSGGERQRVL
LARALAVQAQVLLMDEPLANLDPPHQADWLAVVRALVSKGNTVVSVLHEL
SMALHADELVIMAAGCITHQGTCSDAATHRALEAVFDQRITIHPLANQWV
ALPN
>Rfer_3031 L-aspartate oxidase
MNAKNVNTPSTLHFDVLIVGSGLAGLNAALLLAPTRRVAVITKRAMKEGS
SGLAQGGIAAVWDKNDSFQAHVDDTLVAGAGLCDVAATRFVVEQAPQAIA
WLQTMGVPFSEENGRLHLTREGGHSARRIAHVTDATGAAVQDTLIERVRR
TPNITLFENHTLVDLITSAKLDPLGNRQAGANQCLGLYALDDVTDEVITF
EAQHTILATGGAGKVYLYTTNPDTATGDGIAAAWRAGCRVQNMEFIQFHP
TCLYHPHAKSFLISEAVRGEGGRLLLPDGTRFMPQHDARAELAPRDIVAR
AIDFEMKKGGFDCVYLDISHQPLAFLKEHFPNIYARCLELGIDISKQPIP
VVPAAHYTCGGVLADLDGRADLGGLYAIGETACSGLHGANRLASNSLVEC
MVFARAATQVIDQTPVAKPRELPAWDDSRVSDADEAVVISHNWDELRRFM
WDYVGIVRTNKRLERAAHRIALLQGEIHEFYAAFHVTRDLLELRNLVQVA
DLIVRSAQSRHESRGLHFSRDYPQTDAVAQPTTLVP
>Rfer_2012 dihydropteroate synthase
MKWNTARFLIDLSRPQVMGIVNITPDSFSDGGQHASTAAALRHCETLLKE
GADILDIGGESTRPGALSLPLDEELARVLPVVREAVRLGVPVSVDTYKPR
VMQAVLDLGADIINDIWALRWTEPCANPAPAALNAMQVVAKHPSCGVCLM
HMHREPLTMQMAPMEGDVVPQVLLFLEHLAQSLHGLGVEKNRIVIDPGIG
FGKTVAQNFALLARQGELLGAGYPLLVGWSRKSSLAAITATPLAAAATLD
VHERLVPSVAAALLAVERGAAIVRVHDVRETVQALKVLGAIR
>Rfer_3536 putative phenylacetate-CoA ligase
MIEHYDALETRDHTARETALMTALPAQVAHARDSSAAFHQILQDVNPATV
TSRAALASLPVTRKHELLERQQASRAGGGNVFGGFSAIGFGERMPRVFAS
PGPIYEPEGAAKDYWRMARAMFAAGFRPRELIHNSFSYHFVPAGSMMESG
AHALGCTVFPGGTGQTEQQVQAMRELQPAGYIGTPSFLKIIVDKAHEMGV
ALPSVKKAMFGGEAFPPSLRDWFAERGIAGYQCYATADLGSIAYETPARE
GLVLDENVIVEIVRPGTGDPVQDGEVGEVVVTTLNPDYPLIRFGTGDLSA
VLSGPCPTGRTNTRIKGWLGRADQTTKIRGMFVHPGQIADIIKRFPEVAR
ARLVVTGEMANDVMTLKVETACSGPDALAAKIGEAIRDVTKLRGAVEILL
PGSLPNDGKVIEDARSYR
>Rfer_2610 cobalamin-5-phosphate synthase CobS
MSQFIRHYLLSLQFFTRIPVTGRLANWVGFSPAMLRASAGHFPGVGVLVG
ALVAAFTALLLFVLPRTGSTPLVAAALGTALGVLLTGAFHEDGLADVFDG
LGGSAERERALVIMKDSRVGAFGAIAVMLALLCKVALLALLGAVSATLMV
AALFVAHVLSRTWPLLTIRLLPHVGDAAGSKSKPLADQISVAALLTGFIW
CFMALALVISTQSATEYIAINLTDTALLQALLSAVVASCVAWAVMARWFW
RRLQGFTGDCLGATQQVCELAFYLGLAVGL
>Rfer_3782 SSS sodium solute transporter superfamily
MTRLSQFKGAIALFSLLALSAGAYAAGADLGQAVKQTTNWTAIGMFATFV
ILTLGITKWAASRTKSASDFYTAGGGITGFQNGLAIAGDYMSAASFLGIS
GLVFANGFDGLIFSIGWLVGWPIITFLMAERLRNLGKFTFADVAGYRFSQ
TPIRIFAACGSLVVVAFYMIAQMVGAGQLIKLLFGLEYLYAEILVGSIMM
MYVLFGGMTATTWVQIIKACMLLGGATFMAFSVLLQFGFSPEMMFEKAIE
VHSKKDAIMAPGGLIKDPISAISVGMALMFGTAGLPHILMRFFTVPSAKE
ARKSVGWATTWIGYFYILTFIIGFGAITNLIPNPMDYFVGGDISKGLNGG
GNMAAVHLSKAVGGNVFMGFISAVAFATILAVVAGLTLSGASAVSHDLYA
SVWRKGRVDQADELRVSKITTVALGIIAVTLGIAFEKENVAYMVMLAFVI
AASANFPVLFMSVLWKDCTTKGAVAGGFVGLIMAVVLTILSPSVWVAVMH
HPAGSAWFPYDSAAIFSIPAAFLTIWLVSTFDRSARAAVDRAGYPAQEVR
SETGIGSASASGH
>Rfer_1369 glutamate-1-semialdehyde-2,1-aminomutase
MTLNTDNNQILFERAKRVIPGGVNSPVRAFKAVGGTPRFVKRAQGAYFWD
ANNQRYTDFIGSWGPMILGHGHPAVVEAVQAAVLEGFSYGAPTEREVELA
EEILRLVPSMDMVRLVSSGTEAAMSTIRLARGATGRSKLIKFEGCYHGHA
DALLVKAGSGLATFGNPTSAGVPPEVVQHTVVLEYNNIEQLEEAFAMQGS
EIACLMMEPICGNMNFVRASVPFVKRCRELCTQYGALLVFDEVMTGFRVA
LGGAQSVYAKEIPGFEPDMTVMGKVIGGGMPLAAFGAKRAVMEHLAPLGT
VYQAGTLSGNPVATACGLATLREISKPGFYESLARTTRSLTDGLKAAATA
EGLAFSADSEGGMFGFFLLDTLPQNYVQVMKSDSARFNQLFHGLLDRGVY
IAPALYEAGFVSAAHTAEDIAATVAAARAVFKIISK
>Rfer_2467 Thiamine-phosphate diphosphorylase
MSQHDSMVQTIVTAHADLALAPGAGTSQRAATATFTCDAAAYRAAKSACL
ALGFIEADAECVALAWQNQTDRTGHFDVTVWPDQPEDFSMQAWPRPTAFA
ACPRQLGLYAVLPDAVWVGRMARAGVSTVQLRFKSDDTVVIAREVRAAVM
AVKGTNARLFINDHWQAAIDAGAYGVHLGQEDMVEADLEKIRAAGLRLGL
SSHGYAEMLRADHYSPSYIAMGAVFATTLKRMLTPPQGLARLGAYARLMR
DYPKVAIGGIDASKLLDVLNCGVGSIAVVRALVAAENPEVMANSLQAKIN
DRLSAMAPEPAL
>Rfer_0461 aminotransferase, class IV
MPAPDLSKGVAFVRGQYVPIGEASIPITDWGFLRSDATYDVVTVWDGSFF
RLDAHLERFMRSCQRWRLDPGLTPGQITGVLSQCVRLSGLRASYVEMICT
RGQPPWGSRDPRLAVNQFYAFAVPYVWLANAQQREAGLHLMISDVQRIPA
TSVDPSAKNYHWNDLTMGLLGALDAGADSVVLVDSVGNVVEGPGFNVFCV
SHGALVTPSEGMLEGVSRRTVIEMARALGLETQLRALPADELRGAEEVFI
STSGGGVLPVSRVDKRPVGDGRPGPITQRLVQTYWAWHADPVYSQPIDYS
L
>Rfer_1914 molybdopterin-guanine dinucleotide biosynthesis protein B
MKVVGFAGFSGSGKTTLVERLIPALRRRGLRVSVVKHAHHHFDIDHAGKD
TYRHREAGAFEVVVASSKRLALMREFEQAAQLTVHQLIAELYEGVDWVLV
EGFKDSDLLKVEVWRAQARQPARYMDDDFIVAIATDSPDQLPHATLRPVL
DLNDAEALADWLVANQDRFNYCLEDMA
>Rfer_2616 cobalamin biosynthesis protein CobD
MMALALALLVALAVDRYFGEPRVRLHPVVWMGNYLGWAGAWVQRRAQQNP
QQPDFKAFWLAALVWCSGAAIVLGVTWGLQAALGSLPWWAAGVLLGLLLK
PLLAWAMLKSEVLAVEAALAESLEAGRERLSWLVSRDVSALSEAQVREST
IETLAENLNDSVVAPIFWFVLLGLPGAALYRFANTADAMWGYPGIYKGQN
WAWAGKWAARVDDVLSWLPARITALLLLLATGARGLALAGRLRAEAAKTP
SPNSGWPMAAMALGLDVGLRKPGVYVLNPAGRAALAQDTAQALVYASNTL
LALVVIAQAAIIFVAIGARP
>Rfer_1955 Protein of unknown function 1935
MTPSFATCDLCDAHKNDVSGAFRVLPPVFRDFGGVRQFCGPVVTVKCFED
NSSVKAAVESVGYQETPAGRVGKVLVVDGGGSLRRALLGGNLGAAAARNG
WAGVVIDGCVRDVSELAAVGLGIRALASMPLPTEKRGEGQSDLALQIQGV
WVRPGDWLYADEDGMVLAAGRLV
>Rfer_1467 molybdopterin-guanine dinucleotide biosynthesis protein A
MIPAQDITGLILAGGRGSRMGGVDKGLQTFNGMPLALHTLTRLQMGGGVG
QIMINANRNLAAYESFGASVWPDGLADYAGPLAGFLTGLEHCETPFLVTV
PCDTPRLPLDLVPRLAAALEAENADIAMVAAPEIGKDGQVRLRPQPVFCL
LRVELLESLVRFTQEGGRKIDAWTALHKTAVAPFDLPHDDPLAFFNANTL
AELHQLENNPA
>Rfer_4164 putative aspartate 1-decarboxylase
MFRTLLRSKSHRGAVTHCELHHDGSCAIDKVLLGALNIVENEKIYIWNIT
NAVCFITYATHGERGSGMILDICSVATRIPLCAVLAPREY
>Rfer_2611 Nicotinate-nucleotide-dimethylbenzimidazolephosphoribosyltransferase
MTFTLPTLTDIRSPALTLTLQHKIDNKTKPLGSLGRLESLALQLGEILGT
DAPALQDPQLLVFAGDHGLAARGVSAFPSDVSWQMVENFLAGGAAVSVFS
RLNNIALTVVDCGVNHDFLAGLPAGSQRPGLQVRKVPGGEQGTADSSAQA
AMTALQCQQAIQNGMALVKALPGNALLLGEMGIGNTSAASLLLSRLAGLE
IEVCTGAGTGLDASAVQRKTKVLREVLARHPDATTPLDALAAFGGFEIAT
MVGAVLQAATERRVIVVDGFIASSAVLVAHALQPLVLQACVFAHRSGERG
HEFMLQYLGVQALLDLGLRLGEGSGAALAWPLLQSACAMLREMASFESAG
VSEKAETQTAQV
>Rfer_2192 Na+/solute symporter
MLNPAVEVGEFKPIPGGFRLHGWLLAIWFAASFGVVFFARDLQIIVAGWP
LGYWFAAQGSVFIFIAVVAVFAWVANRRDREITTADAAYTAYKHRLHWRF
SAYVVCLLLFLLALALAERLGLKKMWVGSIFLFATVALYAVIGIYGRTSD
ASEYYVAGRSIPAVYNGMAVAADWMSAASFISMAGGLYLQGFSGTPSQPG
GLVYVLGWTGGFCLVGLLVAPYLRKLDLYTVPDYFGVRFGGRWPRMIAAF
AAVLCSFTYVVAQIYGVGLITSRLTGVQFEIGILLGLGGVLVCSFLGGMR
AVTWTQVTQYVVLILAFLIPVSWLAYKQLGNPLAPFVYGQQLQKITELER
QLIDSPAELQVINEYARRARDYERKLQHVEASLESERNTIREKIRFLNEH
RVDESIVVAARRELAALPKDTVSARERWMHAMQDNLDRAQPLGGMPAHAK
PFAGDPQGSADEKKAFDVSRRNFLALTFCLMVGTAGLPHLLTRFYTTRTV
AEARTSVVWSLFFIALLYLSAPALAVLVKFEVMSQLVGQNFDSLPVWIAQ
WAKVDPTLVSVSDVNGDHILQFSELKLGADIVMLATPELGGLPYVVSGLV
AAGGLAAALSTADGLLLTIGNALAHDLFYRGGSSQSEAVRRVMLSKFALL
LVALVAAYVAAQRPADILYLVSASFSLAGAAFVPVMVLGIFWRRTTRLAA
VVGMITGLGLTIYYMAVNSVALRSVLGLSGTGLWLDIQPVSAGVFGVLAG
FVVTVLVSLLSRSESSSPG
>Rfer_0765 glutathione synthetase
MNLLFITDPLESFKIYKDTTFAMMREAQKRGHRVAACEPQDVMWQRGGWV
TAHVRDIALTGQADAWFELKQTRAVALRDFDAILMRKDPPFDSEFFYATH
LLAQAEREGARVFNKPGALRDHPEKLAIMEFPQFIGPTLVTRDEADIKRF
HAEHRDIILKPLDGMGGMGIFRVGPDGLNLGSITETLNRHGAQSLMVQKF
LPEIVAGDKRVLVIGGKPVPYCLARIPQGGEVRGNLAAGGKGVAQALSAR
DLEIAQAIGPVLAARGLLLIGLDVIGDSLTEINVTSPTCFQEIFDQTGFD
VAATFLDALEQAASS
>Rfer_3033 3-methyl-2-oxobutanoate hydroxymethyltransferase
MSASAESTNATPYGTLPPTAAASARKPISLPRLLEMHARGEKLTMLTAYD
ATFAAVADAAGVECILVGDSLGMVCQGLSSTMGVTLQAMCYHIESVARGL
RRAQATAWLIGDLPYGSYHESREQALRSAAALMQAGSHMVKLEGGGWTAD
TVRFLVERGIPVCAHLGLTPQTVHALGGYRVQGKTQESAALMKRQAHELQ
DAGAALLVLEMVPAALAAELTRELTHCATIGIGAGKDTAGQVLVLHDMLG
INLGKMPKFVRNFMTGAPGVKEAMQAYVAAVKNGSFPDNTQHAW
>Rfer_0814 Dihydroneopterin aldolase
MMNSPTSGHSLGQQTLTLTGLRFDANLGILEAERTAPQPIQVDAELSLGA
QPLLPHDDEITHVLDYRKVRKIIIDECTAEHVNLLETLIGKLANRLMQLP
GVLGVRVKIAKLEIFDDCEVAIRMETGQWS
>Rfer_3015 Chorismate lyase
MKVWSKRNVQRGNRKRWVGATGSLSARLAAAGQRFSVQVLSQGLQALDPD
EASALGLSRLKVGYVREVLLRVDEVAVVFARSVTAHPHSQGPWRSIRGLG
TRPLADVLFGQHGIARTPLQFASLQVASSLHRHVAHAWLGATGAALASRV
LPARRSVFTRGAAPLLVMEVFAAPHAPWGWLTTKTRRGPPALPRTKP
>Rfer_0951 mandelate racemase/muconate lactonizing enzyme
MKITKLTTYIVPPRWCFLKIETDEGVVGWGEPVVEGRAHSVAAAVEELSD
YLIGKDPRNIEDHWTVLYRGGFYRGGAIHMSALAGIDQALWDIKGKALGV
SVSQLLGGPVRNSIRVYSWIGGDRPADVAAAAKDAVARGFTAVKMNGTEE
LQFVDSYEKVEAALANVAAVRDAVGLHVGIGVDFHGRVHKPMAKVLIKEL
DQYKLMFIEEPVLSENYEALKELAPLTNTPIALGERLYSRWDFKRILSDG
YIDVIQPDVSHAGGITETRKIATMAEAYDVAVALHCPLGPIALAACLQVD
AVSYNAFIQEQSLGIHYNQSNDLLDYLTQPEVFAYDKGYVTIPQGPGLGI
EINEEYVKERAAIGHRWRNPIWRHRDGSFAEW
>Rfer_3607 anthranilate synthase component I
MISELEFKSLSAQGYNRIPLMAEAFADLETPLSLYLKLAYSKDSGKYSFL
LESVVGGERFGRYSFIGLPARTLLRSMGFGPEVCTEVVTDGVVVETSRAN
PLDFISDYQKRFKVALRPGLPRFCGGLAGYFGYDAVRYIEKKLEKSCPPD
TLGCPDILLLQCEELAVIDNLSGKLYLIVYADPARPEAYANAKKRLRELK
EQLKYSVSAPVVKPTQSHSAERDFAKADYLAAVERAKELIAGGDFMQVQV
GQRIKKRYTESPLSLYRALRALNPSPYMYYYHFGDFHVVGASPEILVRQE
QVTVDGKTEQKVTIRPLAGTRPRGASLELDKAAEVELINDPKERAEHVML
IDLARNDIGRIAKIGSVKVTEAFSVERYSHVMHIVSNVEGTLNDGMTSMD
VLKATFPAGTLTGAPKVHAMELIDQLEPTKRGVYGGACGYLSYAGDMDVA
IAIRTGIIKDQTLYVQAAAGIVADSVPELEWKETEAKARALLRAAELVEE
GLE
>Rfer_3299 oxidoreductase FAD/NAD(P)-binding
MTRSATRAPGFHITVQPSGRAFTTEADETILAAGIRAGVGLPYGCQDGAC
GSCKCKKLEGIVVHGAHQSKALSDEEEAQGWVLTCCAVAHSDVLLESRQV
TREDALPIKKMPSRVSAMEKLSPDVMRLQLQLPASEPFNYHAGQYVEFLL
RDGVRRSYSIANAPHTPAAPDGKPGALELHIRHMPGGQFTDHVFAAMKER
DILRIEGPYGSFYLREDSSKPIVLLAAGTGFAPVKALIEQLQFTGSTRPV
TLYWGGRRPADLYLDAWVRAKLAEMPNLRYVPVVSNALPEDSWLGRTGFV
HLAVLQDLPDLSGYQVYASGAPIVVDSAHAAYTRAGLPPDEFYADAFITE
ADKARDGATI
>Rfer_2883 uroporphyrin-III C-methyltransferase
MTHTPTPPPSPGKPDLPNHSDHQLPATDFSSLSGAGRCTLVGAGPGDPEL
LTLKALKAIQAATLLLVDDLVSDAIVALATPGARIVHVGKRGGCQSTPQA
FIEKLAIMAVQEGETVVRLKGGDPFVFGRGGEELEHLQAAGIRVDVVNGI
TAGLAAATSLGVPLTHREHAHGVVFITGHAKPGDTGTDWRALAATAHSAR
LTLVIYMGVSGARRIQDELLSGLPAHTPVAVIQNASLPTQRQAVCTLGEL
QCTLEREDLASPSVIVVGDVLKGLLALQQPLSQQSLRA
>Rfer_2962 4-hydroxythreonine-4-phosphate dehydrogenase
MKKPIAITLGDCAGIGPEIIAKAFRDAPELTRGCFVVGDVATLRRATKLI
DAGAIPLPVALIESPAEALNVPPRCLPVLQIGALAEPVPFGRLSAEAGKL
AAECVTWAAQAALRGEIAALVTAPLNKEALALAGTPGTHYPGHTEMLQAL
AAAHTHKALAEMPVRMMLANDELRVVLVSIHVSLRDALEAVTFDNVLQTL
RIAHAALSASLGRAPRIAVAGLNPHAGEGGLFGREEIDIIAPAIAAASAL
GLQVSGPFAPDTVFMRARAKPGQPGEFDAVLAMYHDQGLIPVKYLGVEQG
VNVTLGLPLVRTSPDHGTAFDIAGTGQADASSLLAAIVMARRLSQLQNL
>Rfer_1916 molybdopterin converting factor, subunit 1
MKVTVKYFASIREALGLASESVTTDSATLAALRDELIARGGAYADCLARG
RSVRLAVDQVMCDEAVALVEGAEVAFFPPVTGG
>Rfer_3322 acetolactate synthase, large subunit, biosynthetic type
MELSKARIASAAAKTAATSQTPTTPVKQLVATPDENELRGAEILIKALQA
EGVKYVWGYPGGAVLHIYDALYKQDTIQHILVRHEQAAVHAADGYARATG
EVGVALVTSGPGVTNAVTGIATAYMDSIPMVIVSGQVPTSAIGMDAFQEC
DAVGITRPVVKHNFLVKDAHQLAETMKKAFHIARSGRPGPVLVDIPKDVS
FKKVHYAGYPATLEMRSYNPVRKGHGGQIRKALQLLLAAKRPYIYTGGGV
LLSNASAELRTLVDMLGYPCTNTLMGLGAYPASDKKFLGMLGMHGTVEAN
NAMQHCDVLLAIGARFDDRVIGNPKHFAQNERKIIHIDIDPSSISKRVKV
DIPIVGDVKEVLSEMIAMIKEGAVKPDADALGAWWDTIEGWRKRDCLKYD
HGKNDVIKPQFVIETLWKMTKDADTYITSDVGQHQMWAAQYYRFDEPRRW
INSGGLGTMGVGIPYAMGIKLAKPDSEVYCITGDGSVQMCIQELSTCLQY
NTPIKILSLNNRYLGMVRQWQEVEYEGRYSHSYMDALPNFVKLAEAYGHV
GMLVERAQDVEPALREARKLKDRTVFMDIRTDPTENVFPMVKAGKGITEM
LLGSEDL
>Rfer_1433 riboflavin biosynthesis protein RibF
MKVFRGFHHPDVAQACALTIGNFDGVHRGHQAMLALLKGEAQQRGVPSCA
MTFEPHPRDYFAAASHQPDLAPARIGTLRDKLADLALSGVDQTVILPFDA
RLAGLSPQAFIDEVLVKGLGAKYVLVGDDFRFGAKRAGDYALLDAAGVAQ
GFDVARMNSYEVHGLRVSSSAVREALGQGRLQDAARLLGRPYRISGHVVH
GRKLGRALGFRTLNLRFAHWKPAASGIFVVLVHGLSPAPLAGVANMGIRP
SLDPRDVNGGRVLLETHCLDWPDTLGPEGAYGKIIRVELLHKLHDELKYD
SLDALTAGIAQDCLDARAYFSK
>Rfer_0351 aminotransferase class-III
MNPSTLIPPPAWVRRTEQYDTQALQALDSAHFIHPFTDHGDLATRGARVI
TRAEGVYIWDSEGEKLLDAMSGLWCVNVGYGRKELADAAYQQMMTLPFYN
SFFQTTNVPAVKLAARLASLAPEVDGRSFQHVFYSSSGSESNDSNVRMVR
RYWDLLGQPQRKVIISRLNAYHGSTMAGASLGGMSGMHAQGDLPIPKITH
IGQPYFFENGLPGESEAEFGLRAAGWLEAKIVEVGADKVAAFIAEPIQGA
GGVIIPPATYWPEIQRIVDKYNILLVSDEVICAFGRLGHWFAYEKFGYKP
DLVTFAKAVTSGYIPLGGVMVGDRVAKVLIEKGGEFNHGYTYSGHPVACA
VGLANLAIMEREQLPQRVRDDIGPYLARGFEKIAEHALVGVAETCGFTAG
LVLVKNKKRRERFAEALGVGMMCRGHCFQNGLIMRAVGDRMIIAPPLTMT
HDDIDEMLRLIRQALDLTQQELHQKGLI
>Rfer_1570 phosphoserine aminotransferase
MNRPYNFSAGPAAMPQEVLTEAAAEMLDWHGSGMSVMEMSHRGREFVSIY
EQAHLDLRELLAVPDSFKILFMQGGGLAENAIVPLNLSARVSPAGAAGSA
DFVVTGGWSLKSQQEARKYCTVNIAASNESDGHTTLPGPASWQLSHGASY
VHICSNETIHGVEYHTLPDLQALGSEAALVVDCSSHVASRPIDWSRVGLA
FAGAQKNLGPAGLTLVVVREDLLGHALAVCPSAFNYKTVADNQSMFNTPP
TYAIYIAGLVFQWLKRQGGIAAMEARNQAKAALLYDAIDNSQLYYNKVAP
NCRSRMNVPFFLRDESLNDAFLAGAREHGLLQLKGHKSVGGMRASIYNAM
PMEGVQALVNYLHEFQKRRS
>Rfer_0827 Nicotinate phosphoribosyltransferase related
MTERTSLLLTDLYQLTMLQAYFDQGMADTAVFEFFVRKLPSGRNFLMAAG
LEQVLDFLEDLRFTPAELDWLTGCGRFHRRFVDSLRDLRFTGEVQAMPEG
TVFFADEPILRVVAPLPQAQLVETRIINLLQFQTMVASKAARVRLAAADK
LLVDFGLRRAHGAEAGLLSARASYLAGFDGTSTVLAGMNWGIPLYGTMAH
SFIQVHDGEVDAFEHFARSYPKACTLLINTFDTEAAARRLVPLAKKLAGE
GITIQAVRLDSGDLAAHARQVRRILDEGGLPGISIFASGNLDEHRLAELV
AAGAPINGFGVGTRMNTSADQPYLDCAYKLQEYAGLARRKQSEGKATWPG
RKQVYRSYGADGLMTGDVLTTTDDVAPGEPLLVPVMRQGRRLANMPVLNA
VREHAHAELARLPVPLRALAPATAPYCVTLAPPLRQLAEEVDRRIQADLI
MRKSRCQQTA
>Rfer_2471 thiamine-phosphate pyrophosphorylase
MVGASTLAHDVRLQALRLYLVTDQFCAGGRTLADVVAAAVQGGVTCVQLR
EKQLNTRDFLAQALALKDLLAPHGIPLVINDRIDVALACGAQGVHLGQSD
MPVTQARRLLPPEVFIGWSVETLEDVARSAELPVDYLGVSPIFATPTKTD
TLPPWGLEGLRQVRRATTVPLVAIGGIHVGNAREVLLAGADGLAVVSALC
AAQDPCVAALRLRQLIDAV
>Rfer_2478 thiamine pyrophosphate enzyme-like TPP binding protein
MPSTSIRHGGDRVAEALQAHGVRCVFTLCGGHISPILSASKARGIRILDV
RDEATAVFAADATARLSGLPGVAAVTAGPGISNTITALKNAQLAQSPVIL
IGGAAPTALQGRGALQDIDQRPLVAPHVKRFIKIQRVSELGPAVDEAFAV
AQAGVPGPVFIECPVDLLYDEVSIRQWYADAAGKGTSVADRLLRFYLNRH
VKKMFDGSAAVSAPQVRPVLPPRAPDGRLQAALAALAKAERPLLVIGSQA
LVLSKQAEHLAEAVARLGIPVYLSGMARGLLGRDHPLQMRHQRRQALREA
DCVLLAGVPCDFRLDYGKHVRRSATLIAANRSAKDARLNRKPDIAAIGDA
GLFLQALAQAQPASTAAGSRLAAWVAQLRGRDAARELEIDQQAQASGEFV
NPIALFRTLENELGDNALLVADGGDFVATASYVLHPRTPLSWLDPGAFGT
LGVGAGFALGAALARPGGEVWIILGDGACGYGLVEFDTFVRHGIPVIALV
GNDAGWTQIAREQVKMLHDDVATVLARTDYHAVAAGFGAEGIVVKTMMEL
PAALARARALAHSGKPVLVNVWLDKTEFREGSLSM
>Rfer_1291 ubiquinone/menaquinone biosynthesis methyltransferases
MTTTHFGYKTVPETEKAKHVRGVFDSVAPKYDLMNDLMSMGLHRAWKAFT
VMVANVREGYQVLDIAGGTGDLALAFSKKVGRSGQVVHTDINEAMLRTGR
NRLLDAGVSLPTVVCDAEKLPFPSNHFDVVSVAFGLRNMTHKDLALAEMN
RVLKTGGKLLVLEFSKVAPPLEKVYDWYSFKVLPKLGQLVAGDDASYRYL
AESIRMHPGQEELKALMKNNGFGHVDYHNLTGGLVALHVGIKC
>Rfer_1468 Radical SAM
MTDRDTARIVPLLDLRTSTLRIPGATYLPESRITGSGRLIDTLGRPLRDL
RISVTDRCNFRCNYCMPKEIFDKDYAYLPHKALLSFEEITRIAKVFVAHG
VQKIRLTGGEPLLRKNIERLIEQLAALRTPQGQALDITLTTNGSLLARKA
RDLKAAGLQRVTVSLDGLDDAVFRRMNDVDFPVADVLAGIEAAQEAGLGP
IKINMVVKRGTNEHEILPMARHFMGSGIVLRFIEYMDVGATNGWRMNEVL
ASSEVVKLIHAELPLVQLEPSNPGETAARWGYANASGQYDKELGEIGVIS
SVTQAFCSECNRARLSTEGKLFLCLFASQGYDLRSLIRQEGAASDADLAS
AIGHIWQGRGDRYSELRSALAPDAGTGGHRVEMSYIGG
>Rfer_1267 Farnesyltranstransferase
MQVNPSSPKPSLSVIAQDMREVDQVIAHRLDSGVPLVGQVARYIIAAGGK
RLRPALLLLICGALGFKGAQRFNLAAVVEFIHTSTLLHDDVVDDSSLRRG
NPTANETFGNPASVLVGDFLYSRCFQMMVDAQNMRIMQVLADATNVIAEG
EVQQLMNMHNAELDEAGYLQVIRSKTAKLFEASARVGAILAGSSPELEEI
CAEYGQALGTAFQVIDDVLDYTGEAAVMGKNLGDDLREGKTTLPLIAAMQ
RGTASQSALIKEAIETGGVAMLDQVIDIVKTTGALDVAHLAATQEAQRAI
AAARQLPAGPHTECLLQLAAQLLERQS
>Rfer_2550 conserved hypothetical protein
MNKAVMMQREQIATLTFQQASIRLQKLLAREARTIVGIIGPPGSGKSTLS
LRLQALHPDRSQIVPMDGFHLANVELARLGRSARKGAPDTFDSYGYVSLL
RRLRQQTPEETVYAPEFRREMEEPIAGAIPIFPEAQLLIAEGNYLALDQG
GWSHVAGLLDEIWYVEVDHALRLERLLARHMQFGRSRQAAQEWVQSTDEP
NARLIESTMGRVNFKLLAD
>Rfer_2209 Methenyltetrahydrofolate cyclohydrolase
MTTQKFGQIIDGVALSAKLRADVATRVLALKARGVTPGLAVILVGEDPAS
AVYVRNKVKACQDTGVRSVFEKYEATLSEADLLARIAALNADPSIHGILV
QMPIPKHINPHKVIEAISVTKDVDGYATLSAGELMTGAPGFRPCTPYGCM
KLIETTGIDLRGKHAVVIGRSNTVGKPMALLLLQANATVTVCHSATRDIG
YHTRQADVIVAAVGKRNVLTADMVKPGAVVIDVGMNRNDEGKLCGDVDFA
GVKEVAGFITPVPGGVGPMTITMLLVNTLEAAERTVK
>Rfer_2666 riboflavin biosynthesis protein RibD
MTTSLPQPMRDALNLACAALLVAPPNPRVGCVMTDCRENTLGQGHTQRTG
GAHAEIVALRDAKARGNSVVGATAYVTLEPCSHHGRTGPCCDALIAAGIK
KVVASIADPNPLVSGQGFERLRAAGVEVEVMPADDPLAIASRELNIGFFS
RMIRKTPWVRLKMAASLDGKSALENGVSQWITSEAARTDGHAWRARACAV
LTGIGTVLTDNPRLDVRLVDTPRQPHLVIVDSRLETPLDAALFTPGRVIY
LYAAVQNEAKKAALETRGATVIYAPGLEPATRNKVDLAAMLRDLAAREIN
ELHVEAGHKLNGSFIREGLVDEYLVYLAPMLIGLGSGMANFGPITQLEDA
VNLRFHSIEPVGDDLRILARPPGRETF
>Rfer_3218 UBA/THIF-type NAD/FAD binding protein
MTNAFDYETSVTRNSGYISAETQAKIRKTRLLIAGCGIGSSPAVCAARMG
FENFVLVDGDVVDAHNLNRQFYDFADIGKPKVAALKDKILRINPEAKVEA
IEAYLDADNTQEIVGKADIVFDTVDFLDLPAILRLHDSAKKHKAHIFTAL
SVGFGALVWYFPAGSSLTLTDILAPDIAGSSAGGTVPSYADVFASFIQRL
APHLDAEVVEQVSKVLTMMKDGKPCPASQVAVGSFAIGAMAMSMMHDLLA
GNPIPSAPKLVLHSFRSYQTQIVDVSTSQPD
>Rfer_3805 Porphobilinogen synthase
MTTYASYPLGRPRRLRRDSFTRNLVRENALTPHDLIYPIFVVDGQRQRQA
VSSMPGVERLSLDLLLPVAEECVQLGIPVMALFPVIEQSLKTPDGREAFN
PDGLVPRVVRALKKEFPELGIMTDVALDPFTSHGQDGLPSPDPLEDGYIM
NDETVEVLVKQALCQAAAGTDIVAPSDMMDGRIGAIRQALEANHFIHTRI
MAYSAKYASAFYGPFRDAVGSAANLGKSNKKVYQMDPGNSNEALREVALD
IAEGADMVMVKPGMPYLDVVRRVKDEFKVPTFAYQVSGEYAMLKAAAQNG
WLDHDAVMMESLLAFKRAGADGVLTYFARDAARLLQKQ
>Rfer_1897 diguanylate cyclase/phosphodiesterase
MSAWVILFSVAVYLGLLFFIAYRGDKAADAGRSLIASPYVYALSLGVYTS
AWTFYGSVGRAATSGIGFLPVYLGPTVMIALWWMVLRKIIRISKDNRITS
LADFISSRYGKSAALAGLVTVIALVGVTPYISLQLKAISTSFGILRSYPD
ILLLAPPQPPQSIWHDTAFYAALILAAFTIVFGTRKIDAAERHEGLVAAI
AFESLVKLLAFLAVGIFVTWGMYDGVRDIFARAAQVPRIAEVFTIGGSTE
AYRGWTSPADAATRLALAPGTVMDIYQSWAELFSTAFVGMLAIMFLPRQF
QIAVVENVDEAHLNKAIWLFPLYLFLFSLFVLPIAMGGLLHFGTSVNPDA
FVLTLPLAGQQKALALLVFLGGFSAATGMVIVESIALSTMVCNDLVMPIL
LRIKALRLTERADISALLLAIRRITIVLGLLLGYTYYRLAGEAYALVSIG
LISFAAVAQFAPALLGGIYWKGGTRSGALSGLGAGFLVWAYTLMLPAFAR
SGWLPMALLEHGPFAIAQLRPLALFGLDGLDEISHAMLWSMLANVGAYLT
VSIMSGQSLVEQTQAALFVDVFKHGRGAERVWRASGSLLDLHTLMVRFLG
AENARQALVAYARQRGLEWPQEIDAELSRYCEAQLAGAIGTASARVMIAS
VIEEELLRDSLTGLPNRALLLTRIDDAMKRIQIESRRGFALVFLTLDRFR
TITDSLGGAYGDQLLIAIAQRLGTGLRPGDTIARIGGESFAILLDETKDA
EVAARYAEQLQSALAVGFNLEGHELFTTASIGIVLGHSGYVDAGELLRDA
ETASHNAERRGGACYELFAADMRERVVALLEMETELRRAVAHGEEFLVYY
QPVVSLQTGRLAGFEALVRMRRPDGKLVPPSEFIPLTEETGLIVSIGRWV
LTEACRQMHSWQQRYPDHPPMQISVNLAGRQFTQPALLQQIEAALAETGL
ATSSLKLEVTETLLMAHAEEAAVALEKLSALGIKLLMDDFGTGYSSLSYL
YRFPINTLKIDASFVRRMDVDRKSADIIQSIVTLAHALNMDIIAEGVENA
AQLAQLRALQVEYGQGYHFGQPLDAAAAEAMIVARPVW
>Rfer_1594 binding-protein-dependent transport systems inner membrane component
MLFRRVRQLLLLALTLAFMLPVLTVLASWLPWGDSGLAAAQILREMSRTV
LPDYIWTTVRLCAMVGAGVILVGLSAAVTVTLFDFPGRRVFEWALLLPLA
MPAYVVAYAYTDFLQYSGPLQTFLRSSFGLQGRVLPEIRSLGGAAWVFIF
SLYPYVYLLARTALGESATHLMEAARLMGASMRRRVLEVALPLARPAVAA
GAALALMETLADFGVSSYFGIQTFTAGIYKAWLSMDNRIAAAQLATMLLA
LVALLLWLEHRSQKRLRFVTTRGGRANAMDARPLLLRGRQKWLAWGLCSV
PVLIGFVLPVLFMLRPLVADWQALSWPLFLGWALNSLRLGAISAVLAVAL
ALFLAFNLRRRPDLPARVAVQLAGLGYAVPGAVLVVGLLLPVGWLQTLAP
QSSVGFVLTATSFGLVWAYLVRFCAVALQSVQSGYARIPSSFDDSARILG
TGDMGLLRLVHWPLLKRSTAAAALLVFVDVMKELPATLVLRPFNSDTLAV
VAYQLARDERLGEAALPSLALVLVGLIPVVLLSRTLRAASH
>Rfer_1407 putative membrane protein
MSFISVLFALLLEQARPLSKGNPIHAALRAWVRWSTQNFDAGKPFHGWLA
WGFAVGGPSVAALLIYWLLITFVGWPLGVIWSAAVLYACLGFRQFSFHFT
EIRDALADGDEDRARELLASWKQMDASDLPRSEIVRHVIEHSVLSAHRHV
FGVLAWFSVLAAFGFGPTGAVLYRLSEFVARYWQHKSKAHHQPVSDALQQ
TATVIWTAVDWLPARITAISFAVVGSFEDAIDGWRNYESRFNGDNDGIVL
AATAGAVNIRLGVAAPVTAVAANSAPALPPGTVDRRREARPGQTPELAHL
VIIVGLVWRAVVMWMFLLALLTLARLLG
>Rfer_2292 biotin synthase
MSPNPSQQSSAVAFHPSAAPITLPESATWPLADVLALFELPFNDLMFQAQ
QTHRAHFPKGDVELATLLSIKTGGCEEDCSYCPQAARYDTGVEAQKILEL
EQVLDAAREARASGATRFCMGAAWRSPKERDLEKVEAMVRGVKQLGLETC
ATLGMLEEGQADRLKQAGLDYYNHNLDSAPEFYSNVISTREYQDRLDTLG
RVRQAGLKICCGGIVGMGESRQQRAGLIAQLANLNPYPESVPVNHLVQVE
GTPLYGIEPLDPIEFVRTIAVARITMPKARVRLSAGRRQMGDAVQAMCFL
AGANSIFYGDKLLTTGNPEAGDDLALLAKLGLKTHASTLTEAQKERCGG
>Rfer_2843 bifunctional deaminase-reductase-like
MSKLRVESFTISIDGFGAGPNQNLENPLGAGGPALHQWAWPTKTFRTLFG
HDGGTTGTDEEFAARGFRNIGAWIMGRNMFGPIRGPWPDMNWKGWWGDNP
PYHTQVFVLTHHPRESITMDGGTTFHFVTDGIFSALARARQAANGLDVRL
GGGVATIQQYLRAGLVDEMHIAVAPILLGSGERLFADLNMLSLGYQCAEH
AASSNATHLVIKKKM
>Rfer_0337 Dimethylmenaquinone methyltransferase
MNQLGIVKRNITRAEPAAVEKLSRFGVATIHEAMGRVGLMKPYMRPIYNE
ARICGTAVTVLLQPGDNWMMHVAAEQLQPGDVAVAACTTDNADGFFGDLL
ATSFQARGAVGLIIDGGVRDVKDLTEMKFPVFSKAIHAKGTIKATLGSVN
VPVVCAGAQVNPGDVVIADIDGVVVVPAAIAQKVADAAEAREANEGDKRA
IFASGVLGLDYYKMREGLAKAGLRYID
>Rfer_3245 binding-protein-dependent transport systems inner membrane component
MSPVALPGWLRRSVWLGLLPAVALLVLLIAPLGRLVLAGWAGDVSLTGAA
ATEAWSFWLPWQDDYLRWRVLWSLAQAGITCVLALALGLPLAWVLARFQF
AGRTLVLRLLMLPFVVPTLVAALGVLALWGPRGVLGGWLGVNLHNTPWLL
LYGNLFFNLCLVVRAGVDALGQVNARQVAAARSLGATPWRAFWRVEWPSI
APWLMSSLCLVFLYCFAGFGLALVLGGQRYATVEVEIYTLVAHELQLGQA
SVLALWMLLLTGTVALVYALLEKRLAAPGRVEPIARRPPHGMAQWLALLA
ALGVLFVICALPVLAIVWRALDAGWATWVTVLDAEVRGALWNTLRFSALA
LAVATLLGVLHALAAERSVPWRAAAFLPFVVSPVTVAFGLLLLYPSWTAS
LPLLLAAYAVLAYPFVAKSLSAGLDSLPPHVLHAARTLGASPQRTFWRVT
LPLLRPALRRGMAFAAATALGEFAVTLFLSRPEWATLTTLIYQRLGHPGE
SSLDQAMVLACLLMLLALLAFLLIEWPAADHHDRRRSPASAVAVGAFLHA
>Rfer_3565 4-hydroxythreonine-4-phosphate dehydrogenase
MYRPLIAITMGDAAGIGPEIIMKSLAKPALYETCRPLVIGDAARLRQAGA
LCGVDLQVKVRTRIEEATFTFGQVDCLDLGLIPADLPFGKLSAIAGDAAY
RYVAKAVELIKADIADAICTAPLNKEALHAGGHLFPGHTEMLAHLTGTPE
VSMMLVAPKLRVIHVTTHMGLLDAIDRIEPGLVERTIARGHDTLVRAGIP
QPRIGVCAINPHAGENGLFGRGEEEQKITPAITACLARGWQIEGPLPADT
LFFRAGRGDFDLVVAMYHDQGHGPIKVLGIEAGVNVTVGLPVIRTSVDHG
TAFDIAGQGVADERSMLEALRQAIELATRRG
>Rfer_3196 ApbE-like lipoprotein
MASPASDRIQHGRRQLALALPLLACGLVVPSVHAKADVQQSSQILMGTRV
DLTLQGNDSAALAAAATAAFTEMNRLADMMSRYRVTSALNAINLMAGLQP
VPVPPELLRVLLMARQAGQASGGAFDATVGSLRDWDFSPEHPSIPSKQQI
AAQLRLVDQKAGLVISEHAGTAYLTQRGMLLDLGGIAKLPILQAGLGQLQ
SRGVTNAMINGGGDVLVMGRLNGRPWRVGLRDPRQPSQLLGVVSLTQGFV
AASGDYERFMMHDGKRLHHILDPKTGYPSTGPHGVTLISEQLELINGLGA
ALMVAGADAGRTRVGRTPGIDALIVDADSSLWLSPGMAQRFKRS
>Rfer_0843 mandelate racemase/muconate lactonizing enzyme
MKITAIREATKPIKSDIRNAYIDFSKMTLSLVAVVTDVIRDGKPVIGYGF
NSNGRYGQGSLIRERFAPRILEASPESLGDDSGNNLDPHKIWTTMMTNEK
PGGHGERSVAVGTIDMAVWDAVAKIEDKPLYQLLAERYGDGRPKRKVFVY
AAGGYYWPGQGIEGLEREMRSYLDRGYSVVKMKIGGASLSEDCKRIEAVL
RLLGPGQKLAVDANGRFDLKTAVEYAKALSNYGLFWYEEAGDPLDYALQA
ELAQHYAGPMATGENLFSMQDARNLIRYGGMRPDRDWLQFDCALSYGLVE
YLRTLEMLKEHGWSTSRCIPHGGHQMSLAIAAGLGLGGNESYPDLFQPYG
GFPDGVKVENSYVTLPELPGIGFEGKADLYREMSALAS
>Rfer_3509 thiamine pyrophosphate enzyme-like TPP binding protein
MKKTGAWLARYALEQLGIRYTFGIPGVHNTELYDELNKSELITPMLVSHE
GGASFMADGLSRLSDSVGTLLVVPAAGLTHAASGIGEAFLDGVPMLVICG
GIRTDIDWKFQLHEMDLHQFMKGITKATYKIEHTRDVVSTLFEAYRVATT
GEPGPVFIELPMNVQMFPDDVGELPRWAAPALPEPAAATPIDAAVALLQN
ARKPGLFVGWGARDCSAELMALADHLQAPVATTLQGFSVFPASHPLHAGF
SFGPSAVPAARNAFVDCDVLLAVGTRFGEIASGSFGLTVPSQLIHVDICS
HVFNANYPAQVAIEGDARVVVPQLLAALRRVQPAARAETGLAGRIAADKK
AYRQTWYDHDSQGRVNPARFFDALRAATPADAVTVVDDGNHTYLTAELWP
ILTAKSGILPSDFNAMGYSIPAAMGAKLARPDVPVNCIVGDGCFRMTCME
IITATQYQLGVVYYVFCDGELSQISQAQEIPYNRKPCTVLSTIVIDGVAR
AVGAGYFKIATDADLTEQIAAANAMAKKGQPVIVEVSMDYSKRTAFTEGV
VKTNFQRFTLKQKARALGRAVVRKVTG
>Rfer_1708 thiamine biosynthesis protein ThiC
MNAPDKFSQLMSLTREPLPASRKIYVPGTQADIQVPMREIMQSNGEAVVV
YDTSGPYTDPNANIDVRQGLPSVRSPWIESRGDTESYTGRTPFALDDGLK
NGDSESLASLRVQAAGLQRTPRRAKAGANVSQMHYARSGIITPEMEYVAI
RENQKLAWMEQYLGNAEREARLAGNSFGANIPKIMTPEFVRDEVARGRAI
IPANINHPEVEPMVIGRNFLVKINANIGNSAVTSSIEEEVEKLVWSMRWG
ADTVMDLSTGRNIHTTRDWILRNSPVPIGTVPIYQALEKVGGVAEDLTWA
IFRDTLIEQAEQGVDYFTVHAGVRLAFIHLTANRMTGIVSRGGSIMAKWC
IAHHKENFIYSHFDEMTEILKAYDVSYSLGDGLRPGSGADANDEAQFAEL
RTLGELTQQAWQQDVQVMIEGPGHVPMHMVQANMTEQLKACHEAPFYTLG
PLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPDRDDVKVG
IITYKIAAHVADVAKGHPGVRARDDALSKARFEFRWMDQFNLSLDPDTAR
NFHDETLPKDSSKVAHFCSMCGPKFCSMKISQEVRDYAKTRGVSEEQALQ
SGMQTKSEEFRLAGGEMYIPISPA
>Rfer_0339 4-hydroxybenzoate 3-monooxygenase
MSLSIRTQVAIIGAGPSGLLLGQLLHKAGIDAVIVERVSGDYVLGRIRAG
VLEQVTIDLLDEAGVGTRMHREGLVHGGFDMLYGGKRHRIDMNGLTGGKN
VMVYGQTEVTHDLMDARAFAGLPTYYEASDVQVADFDTTHPRVTFTHQGQ
AVTLSCDFIAGCDGFHGVCRASVPRKSIQEFEKVYPFGWLGLLSDTPPVH
DELIYVNSPRGFALCSQRSKTRSRYYLQVPLTDRLQDWTDDAFWQELRLR
LDDDARAQLVTGPSLEKSIAPLRSFVTEPMRFGRLFLAGDAAHIVPPTGA
KGLNLAATDVKYLCNALVDFYQNRSEEGIDSYSARCLRRIWKAERFSWWF
TSLMHRFPDDGPITARFQEAELDYLIHSHAGSLSIAENYVGLPLDFAEPT
R
>Rfer_3032 aspartate 1-decarboxylase
MLRTLLKSKIHRATVTDCELHYEGSCAIDEDLLDAANLLENEQIHIWNIN
NGERFVTYAIRGERGTGIISVNGSAARRAAVGDLIIIAAFAQVPEAQLDG
FKPQLVFVDANNRVQHQRSHIPVQAAAHPQEGRPS
>Rfer_3034 pantoate--beta-alanine ligase
MKIVRTIAELRQHLSAYKHPAFVPTMGNLHEGHLSLLRQAKPLGDVLVAS
IFVNRLQFLPHEDFDTYPRTWEADCQALQAAGCDVLFAPGEQELYPEPQT
YRVQPPAELADILEGHFRPGFFVGVSTVVMKLFACVQPRVAVFGQKDYQQ
LMVIRGMVRQFALPIAVLGVATLRAADGLALSSRNNYLTPLERAEAVHLS
QSLQQMAKALRAGTVDIAALEQQAMVDLTARGWQPDYLAARRRADLQVPA
ADEVAALVQNDGLVLLGAARIGNTRLIDNLEV
>Rfer_3935 lipoate-protein ligase B
MAMDLLRHRLGRIDYLPAYEAMQVFTAARTPETPDELWICEHPPVYTQGL
AGKAEHVFNPGTIPVVQTNRGGQVTYHGPGQVVAYPLLDLKRAGYFIKEY
VYRIEEAVIRTLVEFGVTGHRVAGAPGIYVRLDDPGSHALLPQRPMKSGL
ANPSFGGLGKIAALGLKVSRNCTYHGVALNVAMDLEPYTRINPCGYAGLQ
TVDLSTIGVCAGWDEVAELLGDKLTRYLAP
>Rfer_2465 thiamine biosynthesis protein ThiS
MNVIINQTRHTLPEGATLADAIELLQARAPFAAAVNLQFVPHTRYSQTRL
QRDDRIDIIAPVTGG
>Rfer_3953 Biotin--acetyl-CoA-carboxylase ligase
MDTHVMDAIREAVLPDLPGFRAEWLPQIDSTNSELMRRARAGRLEPVLLV
AGQQTAGRGRLGRQWFSDTGADAKLGSEGSLTFSLGLPLAPLDWSGLSLA
VGVSVVRSLHPDLRLKWPNDVWLRDRKLAGILIETANLADTPEARYAVVG
VGINMKPRAATGLSTPPAWLGEVLPGVEAPEALLRIAAPLVRALKLFEAN
GFSTFQAGFNERDALGGLAVTLSDGTTGVAQGVDGMGALLVHTAHGLKKV
TSSEVSLRPLNPPPYENL
>Rfer_2612 cobyric acid synthase CobQ
MTAKCIMVLGTTSGAGKSWLTTALCRYYARQGLKVAPFKAQNMSNNARVV
ASDKGSGEIGSAQYFQALAARSVPDVRMNPLLLKPEADTHSQVVLMGRVS
DALTAMPWRSRSNHVWPHIAAALDELRSENDVVVIEGAGSPAEINLSGSD
IVNMRVARHCDAACLLVTDIDRGGAFAHLYGTWALLPERERVLIKGFVLN
KFRGDAALLAPAPQMLQDLTRIATVATLPMWWQHGLPEEDGVFDDRSTAS
GAVKQTVAVIAYPRISNLDEFQPLKNIPGLRLMWVRSPAELAGLSASDWV
ILPGSKATSSDLAWLRAQGLDAAVAAHAGRGGAVLGICAGLQMLGKALID
PQGVDGDAPGLGLLPLVTVFELDKTVRHTQATFADGIAAPWHALAAVTVS
GYEIHQGITQPQSTPATAGEVARAVLPGGLAWQNAAGNVLGLYLHGLFED
PGALQALFGAQLNGPVPTLDVVFDRLADFIELHFQPGVLPGLLT
>Rfer_1041 aminotransferase class-III
MSTVSTHVFHRHLQRTPPTAVSGKGVYLTDAQGKTYIDASGGAAVSCLGH
GHPDVLAAMHAQIDKLAYAHTSFFTTEVAEGLADKLIQSAPQGMSHVYFV
SGGSEAMEATLKMARQYFVEIGQPQRQHFIARKQSYHGNTLGALAIGGNQ
WRREPFAPILMPVTHVSPCYPYREQQAGETPEKYGQRLALELEQAILAKG
ADQVMAFIAETVGGATAGVLAPVPGYFKAVREVCDRYGVLLILDEVMCGM
GRTGTLHACEQEGVVPDLLAVAKGLGGGYQPIGAVLAQARIVDAMREGSG
FFQHGHTYLGHAVACAAALAVQQVFERDNLMAQVRARGDFLQNLMHSAWD
EHPHVGDIRGRGLFWGIELVQDRGLKTPFDPARRLHARIKQEAMARGLMV
YPMGGTVDGQYGDHVLLAPPFIASETELTLVIDRLSSAMDAAISAV
>Rfer_2647 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase
MNDLAGKHIVLGLTGGIACYKAAELCRALIKEGATVQVVMTAAAQQFITP
VTMQALSQRPVYDSQWDSRAPNNMAHINLSREADAILIAPCSADFMAKLL
HGQADDLLSLMCLARPLDQVPLLLAPAMNREMWAHPATQRNVVQLKADGA
TVFDVGCGDQACGETGDGRMLEPHELLEDVISFFQPKLLLGQQVLVTAGP
TYEAIDPVRGITNLSSGKMGFAIARAAHEAGAAVTLVAGPVHLPTPRGVH
RVNVTSAQNMLAAAVDYAQKATIFVATAAVADWRPALAAEQKIKKDGSGV
VPTLSFVENPDILATLAQSLRAQSGDLFCVGFAAESQDLLANAQAKRLRK
GVPLLVGNIGPATFGQDDNALLLVQASGVQELARESKINLARKLIAHISI
KTRARGQNDKN
>Rfer_0506 branched-chain amino acid aminotransferase
MSPVTPSMSDRDGKIWMDGQMVDWRDAKIHVLTHTLHYGCGVFEGVRAYN
AVGGTAIFRLEDHTERLFNSAKILRMKIPFSMDEVLAAQKAVVRENKLEG
GYIRPLSWIGDEKLGVSPKGNTIHLMVAAWPWGAYLGEEGMKRGIRVKTS
SFTRHHVNITMTQAKAVSNYSNSILANLEVTDEGYDEALLLDCSGFVSEG
PGENIFVVKDGVVYTPDLSSGALNGITRNTIFHIAKDLGLELIQKRITRD
EVYICDEAFFTGTAAEVTPIRELDRIELGKGDYVGSRGPITEKIQSAYFD
IVNGRNPKYAHWLSKV
>Rfer_0652 adenosylhomocysteinase
MSAVLKPAVLKPNVDYVIADLSLAAWGRKELNIAQTEMPGLMAIREEFSK
SQPLKGARITGSLHMTIQTAVLIETLQALGAQVRWASCNIFSTQDHAAAA
IAATGTPVFAIKGESLADYWDYTHRIFEFGGKKGSALEGPNMILDDGGDA
TLLMHLGARAEKDIKLLAKPGSEEEVCLFAAIKAKLKVDATWYSRRLKNI
VGVTEETTTGVHRLNDMSAKGELMLRAINVNDSVTKSKFDNLYGCRESLV
DGIKRATDVMIAGKVALIAGYGDVGKGCAQAMRALSAQVWVTEVDPINAL
QAAMEGFKVVTMEYAADKCDIFVTCTGNLNVITYKHMAAMKDQTIVCNIG
HFDNEIDVASLDKCKWEEIKPQVDHVIFPAKGKTPSKRIILLAKGRLVNL
GCGTGHPSFVMSSSFANQTIAQIELFTKPKQYKVGKVYVLPKHLDEKVAR
LHLGKVGAMLSELTDEQAAYIGVSKAGPYKADSYRY
>Rfer_3311 monooxygenase, FAD-binding
MTEKALIVGGGIGGLAAALACVRAGVEVDLFERAAEFSEVGAGIQLGPNV
TAVLHVWGLKDVLASVAAFPERLQVRSASSGAELGVLALGSVAQARYGFP
YATIHRADLHALLLTALQSQTGVRLYAGSAAAGFAQHDDGVTLQMADGRE
AHGELLVGADGLWSAVRQQLLHDGKPLATGHLAYRALVPQSSLPERMRSQ
QVTAWLGPRLHVVQYPVRRGDWLNVVAIVQGRMVGEVESWDHSANAAELQ
RLMAATCAPLQGLIHAIEQWRLWPLSIRLPMRGAHEQAQGRVALLGDAAH
PMLPYLAQGAGMALEDAAELGRVLTRDGATRPVARSRDLPALLNQYAQRR
WQRNARVQARAIRNGKIFHATGPMRWGRDAAMKLLGESLLDLPWLYGGSS
L
>Rfer_2172 UbiE/COQ5 methyltransferase
MSAWFLYTFIGVFVVLSSTALFFFALTRGTLIVRGAMGNLEDDAAHVYPL
YSNMRLIKLIDFQPVIAAILLFQYDRLVSAITSGLHHMDLRGKKVLITSC
AFGNVIPRVVTAAVKSGAKRVLIADIIKNELVHANSKLPEFAGKLEFLQE
NATSMKQADESVDANVIFFLLHELPHHLKSVALSEAMRVLVPGGKLYLAE
FHRPDLWVLRALSWTYFKVFEPLGLALWDSHDPLNQLEAMGGFTCERRTV
FFGNFQIVIATKNPKP
>Rfer_3089 molybdopterin-guanine dinucleotide biosynthesis protein B
MKIFGVAGHSGMGKTTLLERLVPAIAARGLVVSLIKHSHKNIDIDRPGKD
SYRLRESGCKEVLLLGNDRWALMHELRGAPEPSLDYLLDRMQHCDLVLVE
GFKNGNFPKLEVWRESVGKPTLWPDWPGIVAIASDTLLAASAQATAPAQL
DLADAASMVDFVLAHAATR
>Rfer_2668 3,4-dihydroxy-2-butanone 4-phosphate synthase
MKDRRMTAPIPVTISPVEDIVADMRAGRMVILVDEEDRENEGDLVLAADH
VSADAINFMARFGRGLICLTLTRGLCERLQLPPMTARNGDKKGTAFTVSI
EAAEGVTTGISAADRARTVQAAVAKNSHPDDLVQPGHIFPLQAVEGGVLM
RAGHTEAGCDLADMAGCTPAAVICEIMKDDGTMARLPDLQLFAAEHGLKI
GTIADLIAHRSRVESLVEKLGSRPINTAFGDFTLHAFKDKTAHAVHLALV
KGQWAAGDTVLVRVHEPLSVLDALEVGRAMHSWSLDAALARIASEGSGVV
VLLNCGESAKQLMAQFDGTARASHGPERGRMDLRSYGIGAQILRECGVHK
MQLMGNPRRMPSMTGYGLEIVGYLGKTNA
>Rfer_2686 FolC bifunctional protein
MKTPIETQKTLSDWLAHCEQLHPVTIDLGLERVRLVAERMQIRFDCPVIT
VAGTNGKGSTCVMLESILLQAGYRTGVYTSPHLVRFEERLRLLGEPVDAA
QLIAAFESVERARCQDDVEVSLTYFEFSTLAILDVMSRSGLDVVILEVGL
GGRLDAVNIIEPDCAIITSIDLDHMALLGPDRESIGYEKAGIMRTGRPVV
VSDPVPPQSVLDRALEVGADLWQVGRDFNVSGDRQQWAWAGRGRRYSGMA
YPALLGANQLVNAAGVLAALMALRERLPVTAQAVRNGFAFVELPGRFQIV
PGQPALVLDVAHNPHAVAALTANLDAMGYFPTTHAIFGAMADKDVALMLA
RINPLVDKWYFTDLPTPRAESANALLLQWQAQNTRKDASAAVYADPQQAL
QAAISAADPTDRIIVFGSFYTVGGILKDGVPRLDAQHLPSR
>Rfer_2095 UBA/THIF-type NAD/FAD binding protein
MTTDRRFTGLARLYGVLGAQRIAAAHVAVIGIGGVGSWAAEALARSGVGH
LTLVDLDHVAESNINRQIHAVEASLGQAKVLAMRDRILSFNPACQVTCIE
EFVEPGNWPTLLPQGVTAVIDACDQVKAKTAMAVWARNTRTLFISVGAAG
GKRQAHLVDIDDLTHTTHDPLLAQLRYRLRKEHDAPRQGRKIGVACVFSR
EAVKAPDASCAVEGDGTLNCHGYGSVVSVTATFGQCAAGWILDRLAG
>Rfer_2402 conserved hypothetical protein
MVDRAAMIICGSTTLMTILMQRRDFGMAVLGLAAQRLPLAATPDQKVRVL
STADRMVVQPVIDDFERTHPGYNIDYVQLGSVELHAQFLTDQGAHADVLW
SSAQDLQTKLVNDGYALRYESPHADFLPRWAMWKNEAYGTTHEPVGIAYH
RQLLAQSEIPTTHLALAALLRSNTRRFRDRVATYDIEKAGLGYLTAAHDA
MASPQSWELVRSLAQCRASLHIDTQSMLESIAAGRTALAYNVLGTYADAY
ARSNADMGVAYLQDYTFVVSRVAFIARKAPNPQGAKLWLDHLLSQTGQRL
LAETGRLYGVRTDMTGPRSAAALKKLLGSAARPIAIGPGLLANLDRSKRN
ALLKRWHAEFEHARV
>Rfer_2848 thiamineS
MKITLKLFASLTDYLPAEAKYTNFVALDIARETTIGQLVDQYQLPAKQVH
LVLVNGTYIAPDKRANQTLAEGDVLAIWPPIAGG
>Rfer_0821 uroporphyrinogen decarboxylase
MNTSTNSSAFAPLKNDTFLRACLRQATDYTPIWMMRQAGRFLPEYRATRA
KAGSFMGLATNTDYATEVTLQPVERFPIDAAILFSDILTVPDAMGLGLSF
ALGEGPKFAHPVQDEAAVAKLAVPDMDKLRYVFDAVTSIRKALNGKVPLI
GFSGSPWTLGCYMVEGAGSDDYRLVKTMLYSRPDLMHRILQINADSVAQY
LNAQIEAGAQAVMIFDSWGGVLADGAFQEFSLAYTARVLAQLKREHNGAR
IPRIVFTKGGGMWLKEMGLLDCDVLGLDWTVNLAKARAIVGDSKALQGNM
DPNVLFASPAQIAAEATRVLDSFGTPYAGEGTGPTHIFNLGHGISQHTPP
EHVAALVQAVHEHSRKMRA
>Rfer_2905 Dephospho-CoA kinase
MRGLVRLGLTGGIGSGKSTVAGLLAELGAAVVDADAIARHLTAPNGPAIA
SIAATFGPDFITSTGAMDREKMRALAYADITARQRLEAIIHPLVRQETQR
QTLLAANQGHPCIVFDVPLLVESTTWREKLDWVLVVDCTPATQISRVMAR
NALTRDEVEKIIASQASRRHRLNAADAVIFNDSLSLGALALEVDEVARHF
GLSCQPLSPNQK
>Rfer_1037 aminotransferase, class IV
MNALPPLPSYLNGEFTELPDAKISVMDRGFIFGDGVYEVVPVYGGRLFRF
EQHMARLDRSLTEVRIANPMTQAQWAEVALKLVSSYAAYTGAKAENINQL
VYIQITRGVAMRDHVMPTDITPTVFVMANKMNLPTDAQRSQGVVCVTADD
FRWEKAHIKSTSLLGSVLARQISFDAGAVETIMFRDGFLSEAAASNVWVI
KDGKVLGTPKDNLVLEGIRYRLLEEICRSKGIDFELRRVSRDEVVTADEL
LLSSATKEVLAVTTLDGRPVGAGRPGPVYAQLYAGYQKAKEQA
>Rfer_4040 molybdenum cofactor biosynthesis protein C
MNALTHFDAQGQAHMVDVAGKAATHRIGIAGGRIEMLPSTLAIIEAGTAK
KGDVLGIARIAGIMAAKKTSELIPLCHPLALTRVAIDFETDQADETRASS
IFCTATVETVGATGVEMEALTAVQVALLTIYDMCKAVDRGMVMTGIKLLE
KHGGKSGSFVNGT
>Rfer_0133 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MKRVIVAISGASGAVYGVRLLQMLRGMQGVQTHLTVSEAGWLNVQQELDM
ARAEVEALADVVYPVQNVGAAIASGSFQCDGMVVAPCAMRTLAAVALGLS
DNLITRAADVMLKERRRLILMVRETPLNLAHLRNMTSVTEMGGIIFPPVP
GFYHRPQSINEMVDHSVSRVIDLLGLPQPDATRWTGLAS
>Rfer_3324 ketol-acid reductoisomerase
MKVFYDKDCDLSLIKGKTVAIIGYGSQGHAHAQNLNDSGVKVVVGLRKGG
ASWTKVEKAGLKVAEVADAVKAADVVMILLPDEHIAAVYTEDIEPNIKQG
ASLVFAHGFNVHYGLVTPRADLDVWMVAPKAPGHTVRGTYVQGGGVPQLI
AIHQDKSGRTRDLALSYAMANGGGKAGIIETTFREETETDLFGEQAVLCG
GTVELIKAGFETLVEAGYAPEMAYFECLHELKLIVDMIYEGGIANMNYSI
SNNAEYGEYVTGPKIITSASKDAMRQCLKDIQTGEYAKSFILENKAGAPT
LLSRRRLTSEHQIEQVGEKLRAMMPWIKKNKLVDQTRN
>Rfer_2875 deoxyxylulose-5-phosphate synthase
MPHNSYPLLHTINDPADLRLVPRAQLGALADELRAYLLHSVAKTGGHLSS
NLGTVELTVALHYVFNTPHDRVVWDVGHQTYPHKILTGRRERMATLRQLG
GLSGFPQRGESEYDDFGTAHSSTSISAALGMALAAKIRGEERYAIAVIGD
GALTAGMAFEALNNAGVADCNLLVILNDNDMSISPPVGALNRHLAKLMSG
QFYAAAKNVGKTVLKGAPPLFELAKRLEESAKGMVVPATLFEKFGFNYIG
PIDGHDLDALIPTLENIKHLKGPQFLHVVTKKGQGYKLAEADPVAYHGPG
KFDPAVGLQAPATSPKQTFTQVFGQWLCDMAAVDPRLVGITPAMREGSGM
VEFEQRFPQRFFDVGIAEQHAVTFAAGLACEGLKPVVAIYSTFLQRGYDQ
LIHDVAIQNLPVVFALDRAGLVGADGATHAGAYDIPFLRCIPNVSVACPA
DENECRQLLSTAFAQNHPVAVRYPRGAGAGTVVQAGLEALPFGQGEIRRA
GSSVAILAFGTLLHPALQVAEKLNVTVVNMRWVKPLDVALLLQVAADHDA
LVTVEEGAIMGGAGSAVLEALQAAGVLKPVLQLGLRDEFIEHGDPAKLLA
LQGLDAAGIQASITKRFAALLVPGRLALKAVA
>Rfer_2059 pyridoxamine 5'-phosphate oxidase
MGERGGGIQSIKNQLPPESKDKVLTIRPKDQPAYTLSPMTSIAHLRKSYE
RAELSEDASHADPLQQFEKWLKEAISAEIPEPNAMTVATVASNLRPSTRV
VLIKGYDERGITWFTNYDSRKGQELAGNPYAALQFHWVELERVVRIEGIV
EKVSEEESDSYFHSRPLDSRIGAWASPQSQVISGRSVLVANAAKYGAKFL
LNPPRPPHWGGYRLKPDHWQFWQGRKSRLHDRLRYTLIEPASTLPDAKPV
WIRERLAP
>Rfer_1915 MoeA-like, domain I and II
MTRPGSPDSPRAALMPLDDALSQLLAFAVPLADIEFVSTFEADGRVLAQD
LVSDLQVPPHDNSSMDGYAVRCFDVAQALQATAPEAGTLPVSQRIAAGSS
GVPLAPMTVARIFTGAPIPFGADAVVMQEDCEVLPGADGHSSNVVRIKSV
PAPGQWIRRAGEDVTRGAVVLSKGELLTPAALGLAASIGMNLLQVARRPR
VALFSTGDELVMPGDVAPEQMKPGAIYNSNRFFLRALLLRLGCEVSDLGI
VPDRLDATVAALQAAAQDHDLILTSGGVSVGEEDHIKPAVQSLGQLDLWQ
IAIKPGKPFAYGRVANAHFIGLPGNPVSSFVTFLLLVRPFLLELQGVTHS
AIKSIAIPAHFTWARADKRREFLRVRRNAAGGLDLFANQSSGVLTSAVWG
DGLVDNPPGQAIAIGDHVRFIPFSELLG
>Rfer_2508 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase
MSGLVRDPITAYIALGANLGDARAAVLRAMRVIAALPATTLVRRSSLYRT
APVEAMGPDYINAVVEVATGLHPLELLLELQQLEQAAGRERPYRNASRTL
DLDILLYGEASMDSPTLVIPHPRMMARAFVLVPLAEIAPLRVSSDQLRAV
SDQAVKLVTDC
>Rfer_2876 Polyprenyl synthetase
MTGSAAFNLSAWSALHLAHVESALERWVRPDAATDAEGGAPVELMAAMRY
AVLDGGKRLRPLLVLAASEAASGERPAAANTPEIALRAACAVELIHAYSL
VHDDLPCMDNDVLRRGKATVHVKFGEASAMLAGDALQAMAFELLTPDDDA
IPARQQAALCRLLARAAGSAGMAGGQAIDLASVGVALTERQLRQMHRLKT
GALLQASVMMGAACGDVSAQAEAALMSYGAAIGLAFQVVDDMLDVTADSA
TLGKTAGKDADQDKPTFVSLLGLERAGVYAQELLAEALAALARSGLHDTQ
ALQGLARRLVNRTC
>Rfer_1631 Putative oxygen-independent coproporphyrinogen III oxidase
MGHYLRPGTLQLAALPPLSLYVHLPWCLKKCPYCDFNSHEMRAAELPEQR
YLAALMADLEAALPLTWGRTVHSIFIGGGTPSLFSPEAIDHLLSGIRARL
RLEAGCEITLEANPGSFEKDRFRAFRGAGVTRLSVGVQSFNDSFLKTLGR
VHDSAQALAAVEEAAQAFDTFNLDLMYALPGQTLADVKQDMARALTFSPP
HISIYQLTIEPNTFFAKYPPPLPEDDTAYDMLDLITDMTGSAGLQRYEVS
AYAAPGHRCFHNLNYWQFGDYLGLGAGAHSKLSFAHRVVRQVRFREPGRY
MEQALAGHCLAQDEEVSRADLPFEFMLNALRLKDGFALQLFSERTGLAIT
TIQAALEQAQAQGLIVRDLARVTPTVRGFDFLSDLQSLFLPKRR
>Rfer_1466 MoeA-like, domain I and II
MKSIDSIAAELAAYDPQALRADTVNTFLARLVEPVAQLEEVGIFQALGRV
LAADVISPISVPPHDNSAMDGYAFDGAQLAAASPLTLKVVGTALAGKSWS
GQVQHGECVKIMTGAVMPQGLDTVVPQELVSHSPGQHPPTAFITLAPGTV
RAGDNRRQLGEDLLQGQPALKKGELLTPAALGLMASLGIEKLQVWRKLRV
AYFSTGDEILSLGEAPREGAVYDSNRYTVFGLLTRLGLEVIDLGVVRDEP
TLLEAAFTHAASVADAIITSGGVSVGEADYTKAMMKKLGDVAFWKIAMRP
GRPMAVGRIPKAKLASSPHETSTISYNINSNFEPSKDAILFGLPGNPVAV
MVTFLAFVRPALLKMMGSTAAAPPLLKARCSEAIRKKPGRTEYQRGVVST
TPEGTLQVRTTGNQGSGVLSSMVQANGLIVLQHGQGNVALGDEVDVMMFE
GVV
>Rfer_1545 Ferrochelatase
MSFFKLSPFAPEPPFRHGQVPRTAVLYCNLGTPDTPTTPDVRRFLSEFLS
DPRVVEIPRLLWLLILHGIILRVRPAKSAAKYASVWLPEGSPLKVWTEKQ
AKLLQGWLAQRGHQVQVRYAMRYGSTSIAEQLDALKAAGTTRVLILPAYP
QYSATTTASLFDAVYAWAGQVRAIPELRFVNHYHDDARYIAALTMSIQRH
WKSHGRPDQLVMSFHGVPERTLQLGDPYHCECRKTARLLAEQLGLSQEQF
KVTYQSRLGRARWLQPYTEPSLIAMGKAGVKRVDVVCPAFTSDCLETLEE
INMEGRAAFLQAGGKEFHFIPCLNDDPEWITALCDITQQHLAGWPTQAAP
DAPQLAASRAAALALGAKQ
>Rfer_2618 cob(I)alamin adenosyltransferase
MQVETPPTDKPYDKPEGERRGLVIVNTGDGKGKSTAAFGLALRAHGRGKA
VKIFQFMKVPSARFGEHRMFEQLGIPIEGLGDGFSWKSQDLAHSAQLARE
GWQKAKAAILSGDYFMVTLDEITYPLIYGWLPLSEVLDTLKARPSHVHVV
ITGRRCPSEIIELADTVTEMQMVKHAFQAGIPAQRGIED
>Rfer_2078 putative nicotinate-nucleotide adenylyltransferase
MKRIGVFGGAFDPPHVAHAALVKAALAELQLDELRVVPTGEAWHKTRTLS
PAPHRLAMAQLAFAELPHVVVDPRELERVGPSYTVDTLREFKALWPTAEF
FLILGEDQAQALPSWHDWQEILQLAIICVATRACSTGAGAKFDLETTHKS
RFRRLLMPALNVSATDIRARFAAHLSVADMVFEPVARYIAHHHLYQTA
>Rfer_1752 Pyridoxal phosphate biosynthetic protein PdxJ
MTTKLSVNLNKVALVRNTRHLGIPSVTRAATLCLQAGANGITVHPRPDER
HIRTDDVRDLALLMQAWPDREFNIEGNPLHNLMDVVHGLVEKKLPVHQVT
FVPDSEGQFTSDHGWNFPGDASRLRPLIAQAHAWGLRVSLFMDADPAAMA
GAQAVGADRVELYTEPYAAAWGTAQQTPQLARFAETARAALKLGLGVNAG
HDLNRDNLSAFIQAVPGVAEVSIGHALIADALELGYSATVQAYLRCIAQG
RS
>Rfer_2458 Phosphoadenylyl-sulfate reductase (thioredoxin)
MSAIDLNARASGNFEAKLLETTAVLQQAARDYAPLSAGTAPRVTLACSLG
AEDMVIAHLINSLQLDIGIFVLETGMLHTETLDLLARLKASSRAPVQVFT
PATEAVVQFVAREGKEAMYKSIELRKACCNIRKMEPLNRALTGKAAWITG
LRREQSGARADVPLIDTSDATRVKLNPLANWTWGDVWHFIAINKIDYNPL
HDQFYPSIGCAPCTRAISLGEDFRAGRWWWEDETAKECGLHVKASPLPEK
APT
>Rfer_2622 cobalbumin biosynthesis enzyme
MTTLNIARSELILGGQKSGKSRRAEALAQSWLKQSDQHHALLIATAQAGD
DEMRQRIARHQADRAQRVPGMSTVEESFKLAEAIGAHSRPDTLIVVDCLT
LWLTNCLMPIDASTVTEDSRQSDVTEKFIINRPLAPVHQAHVAILLEAIA
GAPGPLVLVGNEIGLGVIPMGREVRAFVDALGLLNQSVAQVCQRVTLMAA
GLPLTLKAMP
>Rfer_3134 mandelate racemase/muconate lactonizing enzyme
MSKIINMRVIDVRFPTSQHLDGSDAMNPDPDYSAAYVILETDQPGLEGHG
LTFTIGRGNEICCAAIEAMRHLVVGLDMAWVAEDMGRFWRHITSDSQLRW
IGPDKGAIHLATGAVVNAVWDLWAKQECVPVWKLVSRMSPEEIVRLIDFR
YITDCITPEEALALLKERAVGKRERWTALEREGYPCYTTSAGWLGYDDDK
LRRLCQEATDAGFNHIKLKVGRDKADDIRRLRIAREVLGPDRQLMIDANQ
VWEVNQAVQWVRELAFAKPWFIEEPTSPDDIEGHRVIREGVYPVKVATGE
MCQNRIIFKQLIMRGAIDVVQIDSCRLGGVNEILAVMLMAAKYNLPVCPH
AGGVGLCEYVQHLSMIDYLCIAGTREGRVIEFVDHLHEHFLNPCVIRDAA
YMPPQAAGFSIEMKPESLKHYEFKAKA
>Rfer_1848 Triphosphoribosyl-dephospho-CoA synthase
MGPTPETSAVRRAMAADAQTLGLAAVRALYAEVALEPKPGLVSFRDCGSH
ADMSAETFVRSLFALRGYFPRMAQAGRDGHPFAVLENLGKNAEARMLAAT
RGINTHRGAIFGLGLLCASAGQLQAQGLVFTPQHLRAVLLSTWGETLAHR
ARAARLAAPDSNGQQAAQRFKLRSAGEEAAQAFPVLFEVTLPALQAALQA
GATDRAARVQALFATMAELDDTNCVHRGGMDGLRFVQTSARKFLDARGVM
QTDWLLHARAIHTTFVERRLSPGGSADVLASACWVESLRRATLAEPSATS
ISEGRVAWSRHEMPVFAP
>Rfer_1716 uroporphyrinogen III synthase
MRVIVTRPQREAQQWVLDLSAQGLQAVALPLIEVGPVHDTADVVRAWQHL
GDYVGVMFVSGNAVDYFFRSNSALAPVFIGSIATKTRAWATGPGTARALL
RQGVAPERLDAPPVDASQLDSEALWQVVGPQVQPGDRVLIVRGGDSLGSA
AASSNAAQGAGRDWFANRVMQAGGRPEFVMAYQRGAPEFGSQARELAQQA
ATDGSVWLFSSTQAVVNLSTCLPGQSWAGARAVATHPRIAAAARQAGFGV
VQESRPTLPELVACFKLMQQTAH
>Rfer_1938 oxygen-independent coproporphyrinogen III oxidase
MNTAVAEPISEDLIRRFDVSGPRYTSYPTADRFVEAFSVEDYTQALKLRR
AGGAAMTLPLSLYVHIPFCESLCYYCACNKIITKHHDRAGPYLRYLSREV
DLHTEQLGVGQTVTQLHLGGGSPTFLTDDELRELMAMLRRNFTFAPSGEY
SIEVDPRTIDASRLDTLAELGFNRLSFGIQDFDPDVQKSVHRVQPAEQVF
ALVAAARERGFDSINADLIYGLPLQSPESFDRTLAQVVELRPERIALYAY
AHLPERFKPQRRIPTVEIPSGAAKVAMLARSMAAFMGAGYVYVGMDHFAL
PTDSLAIAKRQGRLHRNFQGYSTQPDCDLIGLGVSSIGRIGATYSQNAKT
LEEYYDYLDQGRFPVVRGLALTRDDLLRRAVIMAIMCQGQVLFESIELAH
LIEFRKYFAPEMEALQKLADQGMVTVDDVGIQVTDMGWFFVRAVAMVFDR
YLQTDRTRARFSKII
>Rfer_2472 Hydroxyethylthiazole kinase
MAAKLSFSDLWSDVCAVRDRSPLVHSITNLVVINFNANVLLAAGASPVMA
HAHEEVADMVGIAQALVLNIGTLDPYWIESMQLALRAAAKRGIPVVLDPV
GAGATKYRNEAIEQLLMTSLPTVVRGNGSEIMSVAGSAAQTRGVDSSAAA
TDALGAAQSLVQRTQGVVCVSGQIDHILDASHRWAQLSNGHAWMTRITGV
GCSATALIGAFCAVQPDAWRATVAAMALLGVVGEVAAEKVIARGKGVGSL
QMALLDELQLLDQGTFEQRLKLEVAQW
>Rfer_2669 Riboflavin synthase
MLDANQGTLAASDSRLNGKKLRIGIVQARFNEPITNTLAQACKAELLALG
VAEKHIDLVQVPGALEVPVALLALAEKLEYDALVAVGCIIRGETYHFELV
ANESGAGVSRVALDYQIPIANAILTTENLAQAIARQTEKGRDAARVAVEM
ANLLSDI
>Rfer_1917 molybdopterin biosynthesis MoaE
MENQATSPRVSIQTADFDLSTEVALLRAQDPRVGAVCSFIGTVRDRTAGT
SGSISSMELEHYPGMTEKSIEAMMDAALKRFDIYGARVIHRVGLLQPLDQ
IVLVAVTSAHRGESFKACEFLMDYLKTQAPFWKKEQTPEGARWVDARVSD
DAALARWGIAASN
>Rfer_1307 UBA/THIF-type NAD/FAD binding protein
MTDEQLLRYSRHILLNEIGIEGQAQILSSHALIVGAGGLGSPVALYLGSA
GVGHITVVDHDRVDMTNLQRQIAHTMERVGQPKVLSIQTAIAAINPDVQV
TPIMLRADAALLDTLVAQADVVLDCSDNFATRHAINTACVKHRKPLVSGA
AIRFDGQVCVYDPRDANSPCYACVFPPDNTFEETRCATMGVFAPLVGIIG
SLQAAEALKLLSAVGNPLTGRLLMLDGRAMEFTEVRIARQAGCPICGAAH
>Rfer_3246 ABC transporter periplasmic binding protein, thiB subfamily
MNRRLFTLAATALAAFSLSTQARAADELRVMVHSSFSLPKPLLAQFEAQN
GIRLAIIKGGDAGEMLNKLILTRAQPIADVVFGIDNTLVGKALAAGVLEP
ALPQTAEAPDANLGAALAAVDYGFVTLNYDKAAVAKRGISLPKTLQDLTL
PAYKNWLVTPNPATSSTGYAFMLATISAMGEEPAFAWWAQMRGNGLKVVK
GWSEAYYTDFARNKGAYPLVVSYATSPAAEVFYSKEKTPESPTASLNLKG
GVFRQVEGVGLVKGGGQRATALKFVDFLRSAPVQEALQTAMWMYPVQAKT
PLAEVMRHAAEPTEFEAPATQVVAGKGAQWVARWTKVVLK
>Rfer_1637 Dimethylmenaquinone methyltransferase
MTTETLPLDADLIRTLSNVTTATLTTVLLKKGLRHVWLKGTMPIKSDQPR
RVGRAFTLRFVPAREDLATPESWSSPISTRAAIEAMPAGCIAVVDAMGVT
DAGIFGDILCTRMSKRGVAGLVTDGVVRDLAGVLASGFPVWCAGTAAPPS
VAALTFVSWQEPIACGGVAVFPNDVIVVDSDGAVLIPAALLEEVVALAVE
QERLEAWIMNEVEKGAALPGLYPPNAATKVRYEASKEKA
>Rfer_0518 thiamine pyrophosphate enzyme-like TPP binding protein
MNLTESLLHALKAHGARQIFGIPGDFALPYFRIIEKSAILPLYTLSHEPG
VGFAADACGRISGGLGVAAVTYGAGAFNMVNAVASAYAEKSPLVVLSGGP
GKGESQSGLLLHHQAKTLDSQFQIYKEITCDQVRLDDAERAPADIARALA
NCLRHSQPVYIEIPRDMVAEPCLPVTAQAALAVDPDALDACVTDILQRLA
QASAPVLMAGVEVRRFGLEAKVAELSSRLALPVVTSFMGVGLLAQTEAPL
VGTYLGVAGLPEVTQLVENSDGLFLLGVIVSDTNFAVSEKKIDLRKTIRA
LAGQVTMGYHTYSHIPLAALVDHLLLRVPATDKKFSVKHQSYPHGLVADA
ASITPTDIATAVNDLMARHGKLPIASDMGDCLFTALDIEHTALIAPGYYA
TMGFGVPAGLGLQAATGERPLILVGDGAFQMTGWELGNCRRYGWDPIVLL
FNNASWEMLRTFQPESGFNDLDHWGFAEMAAGMGGDGVRVNTRAELKAAL
DKAIATRGRFQLIDITIPRGVLSETLSRFVAGVKRLSTPQ
>Rfer_2758 extracellular solute-binding protein, family 1
MIKKHIPAACAILFACTAVSAQDQVLNIYSARHYPSDEALYSTFTKTTGI
KINRVDADDAGILARLKAEGTASPADVILLVDAARLWKGEVEGLFQPIKS
KILTEAIPAQLHGKTTADGASQWFGFSTRARVIVYNKDNVQKQDVDTYEE
LGDPKNKGKLCIRSGSHPYNLSLFGAVLEHLGEEKTQAWLKGMVDNMART
PKGGDTDQIKGVASGECGIAVTNSYYLARIMRSDKPEDKAIIERVGVVFP
NQASWGTHVNIAGGAVAKHAKNQANAVKFLEYLASAPAQDQFANGNNEWP
VAKGVKISNPALQTMTGGSFKSETIPISVVGMNQVKVQQMLDRVGFR
>Rfer_2077 Coproporphyrinogen oxidase
MSAVAVGSAHTEAVSSYLQGLQARITAAIADIDDTAFLLDAWQKPAGELL
QGKGITQILEGGPVFERAGCGFSKVSGPRLPPSATQHRPELAGAPFDAMG
VSLVFHPRNPFVPTVHMNVRMLAAKAADGTQVCWFGGGMDLTPYYGFEED
VRHFHSTCKATLAPFGDDKYPRFKTWCDDYFYLKHRAEPRGVGGIFFDDF
SELGFEGSLAMMQAVGDSFLNAYLPIVERRKNTVYGKREREFQLYRRGRY
VEFNLVWDRGTHFGLQSGGRTESILLSMPPLASWSYQNVPAAGSPEAELY
TRFLLRRDWV
>Rfer_2624 CobB/CobQ-like glutamine amidotransferase
MTDSSHERLRMTCCPAILIAAPASGQGKTTVVSALARLHTRQGRRVRVFK
CGPDFLDPHWHALACGAPVYQLDLWINGEADCLARLAAAAREADLILVEG
VMGLFDGNPSAADLAQRFGLPVLAVIDASAMAGTFGALAFGLQHYRPDMP
WAGVLANRVASTSHAGMLQASVREPEQWLGALLHNPAMVLPERHLGLTVA
GEVTDALARLDAAADALAATPLGQMSLADLKRWNVTFSPAPTLSETPVSI
GLPLAGRTVAVARDAAFCFIYAANLDCLRDLGANVVFFSPLNDAALPPCD
AVWLPGGYPELHAAQLAANKTLCDSLAAHVAQHKPVWAECGGMMVLFDTL
VTLEGDMQAQWGLLPGTVTMQKRLAALGPQQLVLEAGTLRGHTFHYSTCA
TPLQARWRTARPGCEATPEAGEALYRVGSIQASYFHAWFASCPAAVVALF
SPPVDVPSPGTAP
>Rfer_0882 thiamine pyrophosphate enzyme-like TPP-binding
MTSSRTGGQILVDQLLVHGVQQLFCVPGESFLAVLDALYDASITVSVCRQ
EGGAAMMAEAQGKLTGRPGICFVTRGPGATNAAAGVHIAHQDSTPLLLFV
GQVAREALGREAFQELDYSAVFGSMAKWVVQIDDARRLPELVSRAFHVAT
SGRPGPVVIALPEDMLREAASVADALPYTVTEIHPGAAQLTELQERLANA
QRPVVILGGSRWSDAAVQQFTRFAEAFSLPVFCSFRRQMLFSANHACYAG
DLGLGANQRLLARIRQSDLILLLGGRMSEVPSQGYELLGIPAPQQDLVHV
HADANELGKLYRAAQSIQATPRAFAQAVCTLRPKAPVAWAAATIDAHEDY
LRWSDPAPIRIPGPLQMGEVMQHLRATLPADTIFCNGAGNFATWVHRFWP
FTSYASQLAPTSGSMGYGLPAGVGAKRLWPQREVVVFAGDGDFMMHGQEF
ATAVQYDLAIIVVLLDNAMFGTIRMHQERNYPGRVSATQLKNPDFCGYAK
VFGGHGERVTTTEEFAPALARARASGKPAILHCLLDAQAITPTSTLDGIR
GAALAAAR
>Rfer_1546 aminotransferase, class IV
MDNSVMNTLPPLPCYLNGEFTELPNAKISVMDRGFIFGDGVYEVVPVYGG
QLFRFAQHMARLDRSLAELRIANPLTPAQWAEIAHKLIVTHADSTGASVQ
NIDQLIYIQITRGVAMRDHVMPTDITPTVFVMINAMKLPSEAMRSQGVAC
VTADDFRWEKAHIKSTSLLGSVLARQISFDAGATETIMFRDGFLSEAAAS
NVWVVKGGKVLGTPKDNLVLEGIRYRLIEDICRARGIPFELRRLSREEVR
DADELLLSSATKEVLPVTTLDGKPVGQGKPGPVYAQLYAGYSEAKAQSRQ
SPTA
>Rfer_1715 porphobilinogen deaminase
MSTLTIATRESRLALWQAEYVQDLLTRRGHQVGLLGMTTLGDQILDRALS
KVGGKGLFVKELEVALEDGRADLAVHSLKDVPMELPDGFALACVMEREDP
RDAFVSNQYANLASLPQGAVVGTSSLRRMALLRALRPDLKIEPLRGNLDT
RLRKLDDGMYAAIVLAAAGLKRLGLSQRIRATFEPTDMLPAAGQGALGIE
VRSQRQDVIDALAPLAHHTTWLAVSAERAVSRAMGGSCSMPLAAYATLAA
DILTIDAAWGDPDGKLALVHVRASAAVSDLASATALGARVAADLRAAVLA
NGGTLLVADAPQGQA
>Rfer_2613 6-pyruvoyl tetrahydropterin synthase and hypothetical protein
MLTITRKMEFDAGHRIPDHKSQCRNMHGHRYTLLITLTGDVVQQEGESDN
GMIMDFGDIKALANQHLVKLWDHAFIVYAHDTVVRDFLDSMPNHKTVVID
RVPTVENLAKIAFDILKEVYHGRYGRHLSLAKVTLYETPNCWAEIDG
>Rfer_2144 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
MKPKILIARAIFPEVVAKLAQHFEVTSNQADELWTSAQLIERLKGKQGVF
TTGGERIDAALLAACPELKICANMAVGYNNFDIAAMTAARVLGTNAPDVL
TETTADFGFALLMATARRMAEAEHFLRAGQWTRWRYDMFAGADIHGSTLG
ILGMGRIGQGIAKRGAHGFGMQVIYHNRSRLDAATELECKAIYVSKQELL
KTADHLVLVLPYSASSHHAIGAAELAQMKPTATLVNIARGGIVDDAALAL
ALRNKTIAAAGLDVFEGEPAVHPDLLTVPNVVLTPHIASATMPTRLAMAN
LAADNLIGFLTQGKPVTPLNPAVLVTP
>Rfer_1410 transcriptional coactivator/pterin dehydratase
MNTIHKTNEALAPVKHALKATEVVANLAKLEGWRLAGDGAAVAIEKTFTF
ANYDETISFVNAVAFIAHRQNHHPDLSVHFQRCVVRFSTHDVGGLSMADF
DCAARVDALLA
>Rfer_1689 protoheme IX farnesyltransferase
MSVHVLSVEVSVIKQFYALTKPRVIQLIVFCALIGMVLAVPGLPTWAELQ
LALLACLGIWLVAGAAAAFNCVVEKSIDAKMKRTAWRPTARGELADWQTL
LFSAVLCAAGSILLYFWVNPLTMWLTFATFIGYAVVYTVILKPLTPQNIV
IGGASGAMPPVLGWAAMAGDVGPEALILFLIIFLWTPPHFWALALYRVED
YRKSGLPMLPVTHGNEFTRLMVLLYTFILFAACLMPYVYGMSSWLYLIAA
VVLNLGFCLYAFYLWRDYSDLLARKTFRFSLIHLSLLFAALLLDHYLL
>Rfer_3680 4-hydroxybenzoate polyprenyl transferase
MKSAPSRPRSPLQSRLALYLDLIRWNRPAGWLLLLWPTLSALWVAAGGFP
GWHLLSVFTLGTILMRSAGCCINDVADRDFDRHVKRTAARPVTTGAVSVK
EALVLGAVLALLAFALVLTTNAITIGISGAALAITLAYPYAKRYVSMPQA
VLGVAFGMGIPMAFAAVLGEVPRLAWLLMLGNLFWVLAYDTEYAMVDRDD
DIRLGLKTSAITLGRLDVPVILLCYLAFIVIWDVALMPYVQGALFTIAFA
LAFGQVAWHYTLIRSRSREGCFKAFRLNHWLGFTLFVGIAGSYALR
>Rfer_2239 Coenzyme F390 synthetase-like
MTTVFDPLRLGAVALDVLASGRAAPDAIAARQKTRLAHLLDAAVRGSPLY
RERLQGKTPATLALSALPVLDRAELMARFDDWVTDPQLKAAELRAFTADA
QRIGEPYLGKYLVWESSGTRHQPGVFVQDARAMAVYDALEALRRSAPRPL
QRWFDPLLLAERIAFVGATTGHFASMVSMQRLRQLNPFMAQSLRCFSILQ
STSTLLDELNAFAPTVIATYPTVAALLSDVAAQGALHFAPKEIWTGGETL
SAAVRRHVEQGLGCTVRNSYGASEFMSIGWECQHGQMHANTDWLILEPID
AQGQPVPPGQVSHSTLLTNLANFVQPLIRYDMGDQITVHKEHCECGSPLP
VIEVQGRRDDPLLMAGQDGRLVTLLPLALTTLLEDDAGVFDFQLRQQDDH
TLVLRLDPHGADAAAAAARCRNALEKFAVTQGLARLRVRAELGRPVPRGR
SGKPQRVVAQLKRKHR
>Rfer_1301 GTP cyclohydrolase I
MLMKSQSTMNPSDADEGIPVSVKIRQRLLAARKRFHANDNIADFIEPGEL
EQLLDEVEDKMKGVLSSLVIDTDHDHNTDETARRVAKMYLKEVFNGRYVS
APTITEFPNAEHLNELMIVGPITVRSACSHHLCPIVGQIWIGVLPNEHTN
VIGLSKYARLAEWVMGRPQIQEEAVVQLADLIQEKTQPDGLAIVMEATHF
CMGWRGVKDLDSKMINSVMRGSFLKDPNLRREFLSLIPKKEG
>Rfer_2620 transport system permease protein
MNLRRASFIGWALLGLALLLAALGVCVGSAGFENLLGPLLNPSRDPEQYA
MAHQIVWDIRLPRTLGAWAAGALLGLAGALAQGLFRNPLADPFLLGSASG
ASLGVALVLAAMGGGAGTLGGAMMSDGTAFSVFGTGWLVRLGLTGAAFGG
AVLAVLLTLALSRGVQHTLRLLLAGVVVGVVLGAMTHLVLLWSPESMQAM
QAFMLGSTAFVGWTACAVMAGVWLLASAAGALLARLLDGLSLGEATAHSL
GLPLTSMRFALVAVLALATGAAVAQTGLIAFVGLAAPHLVRSVVKTTHGR
LILLSSLMGGVLLMAADTLARGLIAPQELPVGVLTAVLGGGYLLWLMHRG
TRGGGISL
>Rfer_1318 nicotinate-nucleotide pyrophosphorylase
MLSAMTSYFDFSDLAVAELARVDAARALEEDVGSGDLTAGLIDPACHARA
HVLAREAAVICGAPWAQAALQQVDPAIRLQWLVLEGQRCEIDQVVLELQG
PARALLTAERTVLNFLQLLSAVASKTAEYVAAVQSVPGSRAQIVDTRKTL
PGLRLAQKYAVRAGGGSNHRLGLYDALLIKENHIAAAGGVAKVLRRAAVL
APEAKFVEIEVETLAQLKEALDAGAGMVLLDNMTLAQLQEAVQLNAGRAV
LEVSGGVNMSTVRAIASTGVDRISIGALTKDVKAIDFSMRFASSPL
>Rfer_2406 Holo-citrate lyase synthase
MLAPVSEPISAPVSLEQMLARREARVADQQNLLRRFKRPLVQLTLVTPGP
IKDTSDARFVFEQGLAAMHQALAANGYAVLASEGACFMTGPEALLVVDAD
PLTIKRCLMALEEQHPLGRLWDLDVMGLEGASLSRRQFDVSPRRCLLCDQ
AAHACARGGIHALAQLRRAIQDKIDAYRNSPAN
>Rfer_2405 Triphosphoribosyl-dephospho-CoA synthase
MPTATALRIDAGSGASDLGEAIGRLAERSLVLELELTPKPGLVDRANSGA
HRDMDVGTFRASIAAISPWFSFFFERGVDGSAVPVEDFLRYIRADGMACE
RAMFAATLGVNTHKGSVFSFGLLCAAAGRLHGRGRPLSRASVCAEVSHIC
AGLVKRELLLPAAARTAGELLYWQHGLTGARGEAQSGFATACAHGVVPYL
LARAKGMDEERSLFEALLQLMAHNRDTNIVSRGGMEGLCLVQAEARRLLD
CPTPSRSARTAQLAAFDQLLIERNLSPGGSADLLAVSWFLANLDELVCKC
VA