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# Thiomicrospira denitrificans ATCC 33889, ATCC 33889

>Tmden_0034 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
MKIVILDALTFGDSDLSTFYSLGDTQIFQTTLSSQLQERIKDADVIVTNK
VVITDEHMQNTPSLKLICVAATGMNNVDLEGAKKRAIEVKNVSGYSSDSV
IQHTFSMLFYLIGHSKYYDNYVKNGSYAKSEIFTDVSRPFFEIKGKKWGI
IGLGEIGRGVANIAKTFGAEILYYSTSKKNQNNQYTSVSLDELLKSCDII
SIHAPLNENTLNLLDYKELQMCKDGAVILNLGRGGIINEEAVSRIVDERD
ILFGLDVLSREPIESNNPLLHVKNRDNLYITPHIAWTSIEARKTLIDGVT
SNIKSFYEKNK
>Tmden_2020 Molybdopterin cofactor biosynthesis MoaC region
MKLTHLDEKDRPKMVDVSDKEQTTRVAVASGIIEMSQDAYDAIVTQKTKK
GPVLQTAVIAAIMGSKKTSELIPMCHPINLSGINCDVEELPELPGFKLSV
TAKLTGQTGVEMEALTGTSIGLLTIYDMVKAIDKGMVIRNIQLEEKAGGK
SGDFKR
>Tmden_0462 Anthranilate synthase component I and chorismate binding protein
MTFEDINSLGSKREPFLFIVDFKAQNIALLPLDKLKQNDVEFEINEEYKL
KVHEDFLQKDGVSFETYKEKFDFVIEKIKDGETYLLNLTQPTYIKTPLTL
QEIYSAANAPYKLRYKDKFVCFSPEKFISIKDYKISTFPMKGTIDASILN
AKEIILEDKKEMAEHVMVVDLLRNDLSMVAKNVKVEKFRYITKIEAGEKK
LLHVSSHISGDVGDDWHSKIGDILKSLLPAGSISGAPKKSTLEIIHLVEG
YERGYFSGVFGVYDGEVLDSAVMIRFVQKTKDGYMYKSGGGITLDSDVKS
EYNEMLDKVYLP
>Tmden_1930 Lumazine-binding protein
MFTGLIREIANVKSLRGSKLSIRAKHKASIGDSIAINGACLTVIEISSDG
FSVELSPESQSVLAMENYKNEVHIEPAMMMGDRFEGHIVQGHIDAIGEIK
EIKNSGNSYDVYIKIDKKFIAYIIPKGSITVDGISLTVNEVFDDSFRLTI
IPHTMKETLFKNYKRGSKVNIETDMFARYVAHIISHKKNSLSWDEVDAIS
ASY
>Tmden_0217 Thiazole biosynthesis
MQNLLKIGKYELGSRLIVGSGKYKDFQTTKEATLASGSELITVAVRRLNI
TDPNKENLRDTFKGTNVKFLPNSAGCVTAEEAITTFRLTREATGIDLIKL
EVIGDTQKTLYPDVIETIKACQILSKEGFIIMAYTSDDPIMAKRLEDAGA
HAIMPLAAPIGSGLGIQNPYNIVFIREAVNLPVIVDAGIGCASDAAYAME
LGADGVLTNTAIAGAQNPMMMAEAMKHAVIAGRMSYLSGRIQKRPYATAS
SPINGMIQF
>Tmden_1811 4-hydroxybenzoate polyprenyltransferase-related protein
MKRYIDKLKDFNELVMFEHSIFSLPFIFIAMIVAADGWFGFTLLILGVFA
ALSARNFAMGLNRFADRDIDAQNPRTASRPNVDGRLDSTSIFLFTAINGF
VFIAVAYLINPLAFYLSFPILFILGSYSYFKRFSSLAHVILGLSLGLAPI
AGVVAVSAEITPWSVLLSFGVMFWVAGFDLLYSLQDIDFDKEKGLHSIPS
KYGEEATLLLSALFHALAILFWALFVWVAGLGFFAYNAIILSMFMLGYEH
YLVRKDFTKIDRAFFTVNGYLGILFFILIVMDKVLG
>Tmden_0156 Phosphoadenosine phosphosulfate reductase CysH-type
MKEKINFLNKEFKNVPTKELLEFFLKESKDSIALSSSFGAEDQVLSDMVL
KIESETNIFTLDTGRLPYETYDVMQRTNLKYNTKIKVYFPNSEDIEKLYQ
QQGINGFYDSVENRKECCYARKIAPLKRALMGIDIWITGLRAQQSLTRKS
TQLFEWDEENRVIKLNPLILWSEEDVWRYINENSVPYNALHDSGYPSIGC
APCTRAVEEGTDIRSGRWWWESPEHKECGLHIKEIKQC
>Tmden_1647 Dihydropteroate synthase
MEVELLSNDIDIKKYLKNLNVDSGGIAIMSAKAEHHIIMIRELHVGGANI
LKQDALSVGADLAVPRGTVTAQTPYVDAILIATSRELEKLSRKELAQPFG
LKEVAKKLQEILKIKTPSKVEVMGVINANDDSFFSGSRFSEKDAIEAIKK
MIADGADIIDIGGVSSAPSAKVVSKEEELARVKPILEAIHAKKLYKETQF
SIDSYEPLVIEYAIKCGFRIVNDITGLSNDEVCKLCASNDIRAIIMHMQG
TPQTMQEKPEYENILSDVYTFFEQRIDKAKSFGVKDIVLDVGIGFGKTLE
HNLKLIKHLKHFSTLGQPLLVGASRKSMIDKISPSHVSQRVAGTLALHLE
AAKNGASMLRVHDVYKHVQALKVKKALDEI
>Tmden_1277 Anthranilate synthase
MIYSKQFFQDQLAPIAVYAKLKTIFKDEISFLFESAGQSDGNYSFICMGA
RESIKYMDGKTIYSDANGLSHYSDESPFTFLKNYYKDIDISIYKKASSEL
KVGYVDGFIGYIGYDMVKVFEPKLHSKMDTLKDELNTPDLDLILPKMILV
YSHKNHQLTLISTLKEMSDKFDMIESELKESYKYIDMVKNIGNDKGSFAH
TKEQFFKMVDDSKEMIRSGDVFQILMTNRFTRNIKVDPFSFYRILRTKNP
SPYMFLMEYKDFNIVGSSPEVMVRLTNGELLLRPIAGTRKRGSTKQRDKE
LEAELLTDPKELAEHLMLIDLGRNDVSRVAKTGSVRVEDMMHIERFSHVM
HIVSDVTATLADNKDMFDLFMATFTAGTMTGAPKIRAMELIAEFEGLKRG
FYSGSVGYFGFDGNMDSAITIRTAMVKDDKVILQAGAGVVADSQNELEYL
EVKNKLGALVASLEDLD
>Tmden_0112 Cobalbumin biosynthesis enzyme
MKKTLFIGGIKSGKSLNAQNYILASSLQKPIYLATTEFIDKELQERINAH
KQSRMDSFETIEEPLKLYNKILECKSAILVECVSMWINNMLYHGFTFADM
KEELEKILELDKTVVFVLNDIGSGVIPDNALAREFVDISGKLSQLIASKC
DEVYHTIAGISTRIK
>Tmden_1936 hypothetical protein
MVDLEHFRAIFKPLPGNHYLEVSTTTDEITKLFSDMMQGVGGEFNLALYG
KNKQNLHAINARVQYIDDFKAPFRALPRDHDAVLLKDIFHLHQNQEMMLK
LSYLTLANTANIIIMEKKGILDIDKVVKQLEDFEFRAPNTIEAVERYDLL
IAKKMHMWGNGL
>Tmden_1539 ABC transporter-related protein
MELKPVIEVNNLHFSYKNHNVLSGVDLKLYKGEVVSLLGPNGCGKSTLIK
LILKLIKGRGEIAIANKALESYSHKEIASHVAYIPQYNNTPFNYSVLEMV
LMGRVSKLGFFAIASANDYEVANKALQKIGIEHLRDKAFGQLSGGQKQMV
LLARSIAQEVNIFIMDEPVAGLDYGNQIRLLELISELSAQGYTFLKTTHY
PDHALLISSRVVVMDGGKIIADGAPAEVITKEMIQDVYSINTDIITHDSH
KRCVPIFQKTI
>Tmden_1654 Putative oxygen-independent coproporphyrinogen III oxidase
MLLYIHIPFCDSKCSYCAFNSYVDKFHLKENYMLALSTQLEFELKRFDVR
ANSIESVFIGGGTPSTVEPKHYKAIFEKLKPYLMDNIEITSEANPNSATC
KWLEGMYELGVNRISFGVQSFDKEKLKILNRSHSAAQAKEAILNAKEIGF
KNISLDLIYATLGDTKELLKHDLETAFSLPINHISAYALTIEERTPFESK
PYMSNERLSLTSWLFKNIKDRGFLQYEISNFGKYKSTHNLGYWLYKDYIG
LGSGAVGKLRLQRYYPTSDVEEYINNPTLTKIESLSDEDKKIEQIFLGLR
SCVGVSIDILNNKELQKAKILVDEGKLIFENDTFYNNEYLLADEIALFIS
>Tmden_1411 Biotin--acetyl-CoA-carboxylase ligase
MQILYLECVDSTQKYLKELILKEEVSLPYAVVADVQTDGVGSRDNKWDSI
KNNLFLSFAIPFSELPTDLKLESASIYFSYILKETLEELGSKIWLKWPND
LYICEKKIGGMITNIVKDNVVCGVGLNIVESPEGFTKLDIVLKRDFLLER
YFINIKKKSLWKQVFSKYKLEFDKNQNFYTHDKNLIISLGNVTLQDDGSI
VINGERIYSRR
>Tmden_0864 Carboxylyase-related protein
MKKTIELLKKNGELRIVDTELDIYLEIPHLAYAEVKKKDGGLALLFTNVI
DKKSGKKFDEEILMNVFGSYSRCELLFGRTIESVADEITKLLHMKPPSGF
LNKISMASELFSLKNIFPKKLSREGECQKIKYLENEIDLYKIPVLTTWEQ
DGGPFITMAQVYTQSFDGEMVNVGMYRLQVYDKNHLGMHWQIHKDSSHFF
DQYQKAGKKMPVTIAIGGDPLYTWCATAPLPYGVNELLMYGLIKKESAKL
VKSLTNPLYIPHDVDYVIEGWVDTNEMKIEGPFGDHTGYYTLEESYPVME
VSAITTKKKPTYLATVVGKPPLEDKYMGWATGKIFFPLLKTTAPDLLDYH
MPENGGFHNLILAKMQPHYKGHAKQFMHAFWGAGQMSFVKHAIFLDEKAP
KLDSYDAVTSYILDRFTPKSLFITEGILDALDHSSDEALIGGKLGIDVTA
ANRVEAPNLLGDEELLIRVKELIPDVVNLHQFMRRTKNPITVISVDKTKN
AKHYFEALIPLSMHLRVVVFIDAHKNDIFNAYMLVWRVTNNMDALRDIYI
SGLMVAIDGTNKNSLDSFERRWPDDVDCTQSVVESLKLKGVWDLSEKLYE
KFQLS
>Tmden_1977 Siroheme synthase-like
MSYFPAFLNLEDKRVLLVGGGVVAYTKLSHLLDFTSNISIISLDLSSEIR
ALSKKKNLHVMQRAYSKGDIANFDIVIVAVDNISLQAEIFEESKRYNCLC
SCVDSTKYTHFIFGSYIKKDDLTIAISTSGSSPALAKQLKKYFLKLIPSD
IGIFLQEMKILRETLPKGKERMQMLQRRAEDYMKKWSN
>Tmden_1915 Molybdenum cofactor synthesis-like
MLIDSYDRVVDYLRISVTERCNFRCQYCMPEKPFSWVPKENLLTFEELFL
FVKVAIDEGIRKIRITGGEPLLREDLDKFIKMIFDYAPDIDLAMTTNAYL
LKSTAQKLRDAGLKRLNVSIDTLKPEVAFAIAGKDVLKNVLDGVNEALAV
GLKVKVNMVPMKNMNAQEIVDVLEYSKKRGMTIRFIEYMENKFASKEISG
LKSDELLSMLREHYEFVDEGYDGASPSRYYKMSDGYRFGIIEPYGDDFCK
QCNRIRLTAEGQLIPCLYFDEALSIAKSIKEGDIVAASEVLRDVVKNKPE
KNRWGGEDGEVSTRAFYETGG
>Tmden_1475 conserved hypothetical protein
MSLRDKITRGERIDFDEALLLYEMDFFELGDLADSIRKKKHGKKSYYNIN
RHINPTNVCADVCKFCAYSATRKNPNQYTMTHNQIMEIVKDIDSRGATEV
HIVSAHNPNTGMDWYLEIFKKIKTAYPHLHVKALTAAEVDFLSRQYGKSY
DEILDLMVENGVDSMPGGGAEIFDEKVRDFICKGKVTSDQWFEIHRKWHE
RGKKSNVTMLFGHIESRAHRIDHMMRIRELQDKTGGFNCFIPLVYQTENN
YLNIKEPITANEILKTMAISRIVLDNVANLKAYWVTSTVNLALVAQEFGA
NDLDGTIEKESINSAAGAKSANGVKLEDFRALIKNSGFIPVERDSLYNEI
>Tmden_0423 Uroporphyrinogen III synthase HEM4
MSKNIYLFATSKSKHARSIKSLDVRYLKPEIDFSKYDYLIVTSKQTVKAL
EQYNKEEFINIAALCVSDKTADSYRAIGGKILASGDGYGDNLIKNIRELP
HVTKWLYLRAELIASSFVQIAKEEGYEIDEKILYISECSKEILEVRVEDD
STLIFTSPSSIECFLKNNTIHPNAKVIVIGTTTAAYLPKDIKYVISQNTS
IESCIELAIEAK
>Tmden_1755 probable nicotinate-nucleotide adenylyltransferase
MDTIALFGGSFDPPHIGHEAIIEALKKFKDIDKIIIMPTFLNPFKSNFYA
PSSLRVKWLREIFKEEKRVEVSDYEVLQNRQVPTIETAKHLLESYKKIYL
VIGADNLAKLRDWNSYDELKELVTFVVATRDDIEIPDEFIMLSVDEKISS
TQLRENIQLSKLPKKCAKEIYDFYKEEHCKTE
>Tmden_1486 Thiamine biosynthesis protein ThiC
MRSLWVEKRKDDPVKTQMYYAKQGIITQEMEYVAKIEKLSPELIRSEIAR
GRLIIPANVNHTTLEPMAIGIAATCKINANIGSSAIASDVQGEVEKMQVS
QHYKADTAMDLSTGGDLDEIRKAVIASSKIPIGTVPIYQILHDVGNKIED
LSIEVMLEVLERQAKQGVSYFTIHAGFLLETMPKIAKRKMGIVSRGGSLM
AAWMMHYHRENPFYTAYDEILDICARYDVALSLGDSLRPGCLADASDDAQ
LGELKVLGELTLRAWEKNVQVMIEGPGHVPLNQIERNMKLQRELCHEAPF
YILGPLVTDIAAGYDHISSAIGAAVGGWHGASMLCYVTPKEHLGLPNAND
VREGIIAYKIAAHAADIARGRKGARDIDDEMSDARYRFDWNRQFELALDS
ERAREYHDETLPQDVFKEAEFCSMCGPKFCSYKITQSIMDNPEAIEQIAR
EVKEREALGA
>Tmden_0859 Glutamyl-tRNA reductase:Shikimate/quinate 5-dehydrogenase
MHYLNISFSHKNSTLDVREKLSYKDDYATKGCLSKLNSGESINESILIST
CNRMEVFCSCSDIASATKHIFEMLAARSGVSIDELEGRADIFDDSSAIHH
LFSVASSLDSMVIGETQIAGQLKDAFRFSYDNGFCSQKLARAMHHAFKCA
AKVRNATDISSKPVSIASVAVSKLKSVLDNVEGKKALVIGVGEMSEITAK
HLLSSGADVYITNRTKHKAEKLASECGAKVLDMQDLHKAVNEFEILFTAT
SSSEPIITDEIIKPCDFDRYWFDMAVPRDINYHKGDRINLYVVDDLKNIV
DQNMSFREDGARKAHGIIGRSTVEFFEWLNTLNIEPMIKEIYEKAFEAAR
IESQRVIKKGFIPKEYEDQIHKMSQQVLKRFLHQMSSKMRSVSEESKADM
LTSAVQFLIEKDQRDIPDKYKCEHALNIIEGR
>Tmden_0851 NAD(+) synthase
MEKYAPIAEQLQHFLYEEVHKTGIKNVVLGLSGGIDSAVVALLASRVFGD
NLLCVKMPSHYSSQSSLDDADEFSLAFNLRSITSSIEPMLKAYEEVNPDM
DNLRRGNLSARLRMSTLFDLSAKHNALVLGTSNKSELMLGYGTLYGDLAC
ALNPIGDLYKSEVYELAEYLNVTNSIMKKAPSADLWAGQSDEADLGYTYS
QLDKVLKLYIEEQLSREKILEMGYDAKMLDMIIERNLRNQFKGKMPLIAK
LRQNIRL
>Tmden_1124 Phenylacrylic acid decarboxylase
MKERKIVVASSGASGVNLGIKILELLPQEIEKHFIMTQHAEVVLDKELHI
TIHENENIASSIASGSFGVDAMIIAPCSMNTLAKIACGIADNLVTRCASV
MIKERKQLILAPREMPFSAIALENMHKLSMLGVIIAPPVMAYYSKQQTLD
DMENFIIGKWFDLLGIENSLYKRWE
>Tmden_1290 Adenosylmethionine--8-amino-7-oxononanoateaminot ransferase
MNNEELKKRDLAVLWHPCTQMKDHETLPLIPIKKAYGVYLEDFDGNLYID
AISSWWVNIFGHTNSYINEKIKEQLDTLEHVILAGFTHEQVVRLSERLVK
LTPDGLEKCFYADNGSSGVEVALKMSFHTHKNNQKEKNIFVSLTNSYHGE
TIGALSVGDVKLYKDTYKPLLIQSIQTPVPKDMSIEAAREAACEFEKLCE
KRAKEISAIILEPLIQGAGYMHMYHKEFLILVREICNRYDIHLITDEVMV
GFGRSGDMFACKSANITPDFLILSKGLTGGYLPLSVVLTTDEIYTSFYCD
YSENRAFLHSHSYTGNALACAAANATLDIFENENIIEKNQEIANYMAEEL
LKFKTLKNVLSIRQTGMVCAVELKGYDSKDRIGLKVYEYGLKNGVLLRPL
GHVVYFMPPYIITNDEIKKMMQVAYEAIKELS
>Tmden_0761 UBA/THIF-type NAD/FAD binding fold
MMEYFHRQVQLWGEETQNSLQSKKIAIVGAGGLGSSLCFALGASGIGEIH
VIDFDKVSTHNIHRQIAFKLGDEGKNKAEINAQILEQRCAYVKAIAHDCT
FEEWCKKNIAVDLLIDATDNLNTRAQIDDCAIKRSTPWIYGSVEAFHGQI
CFFENSSFRDAFKINSKTPEGITAPIVMHVASLEANLALRYLAGFNVKKD
QLYYLFFNNDGELVTQKFSLSKSSR
>Tmden_0606 Oxygen-independent coproporphyrinogen III oxidase HemN
MLDFAKFTKYSKPGPRYTSYPTALEFSDSFGYDEYIQKLKSQDSSRPLSL
YFHLPFCKNACYFCGCNVVFTSKEDKMLRYLEYLKRELKILSSFVDCNRS
VIQMHFGGGTPTFFSAEQLDEVIKEIRHFFPNFVKEAEISCEIDPRHIDE
DQMRVLSQNGFNRVSFGIQDFNEKVQIAVHRVQPYEITKYAMDLARKYNM
HSVNVDLIYGLPFQTLETFKETLARSLTLNADRYAVFNYAHVPWMKKTMR
KIDETTLPLPDEKLQIMQYTIDFLTSNGYRMIGMDHFAKPEDELFKAIEK
GELHRNFQGYTTKGGADLIGVGLTSIGEGVSHYAQNFKEMKEYEAAIEEG
KLPFERGVALNEDDMIRQYVIMELMSNFKLDIKRFEKLFNIDFKTYFTDA
INELKPFVDDELLTMNDNFIECSQTGTLLIRNIAMPFDAYMKRHSANAKT
FSKTV
>Tmden_0956 hypothetical protein
MHSKQIAVEYLAPKISNPAMIFKDINIFKSILPWAKDSAKEFFETQTSKM
FLTSYVDDVAPIVDEYLTNRATKMYEKAIKSQNKLFSNLCSSQKTVAWII
DRWINTFINLTSNPAYKDYIDISKIKIAFNDEISTTHSNIEDILEFEKLQ
KLPKEQIIKALKLIWEDGYFDNSLDKEDIEELCKKFDLSIKDVFGTDDLV
KLNLKKEQTQSGHSQLVFVFESEVA
>Tmden_0838 ThiS, thiamine-biosynthesis
MMKLIINGKTEEFEDKITLEKLLDKLDIKEQVMAAAVNMEIVKQNSWDSH
QLYDMDKIELLDFVGGG
>Tmden_0337 Polyprenyl synthetase
MQNFENFLLNHLPASKSIHPTYEEAVQKMLIAGGKRFRPALLLGVVNAYN
PLMIGGAYHAAYAIELLHTYSLIHDDLPAMDNSPLRRGEPTLHVLFDEVT
AILAGDALNTYAFEVLSNAPFSDFTRVELIRELATNGGLNGMVLGQAIDC
YFENRVLSIDDVKILHTNKTAKLIAASLKMGAIIVGEEKLAETLYDFGIK
LGLLFQIQDDILDVTQSSQEAGKLTNNDENKNSFVTILGLDEAFLEAESL
ANTLLKEIDGFDEKLKSELSKLLVHYINRHKN
>Tmden_0863 Porphobilinogen deaminase
MKKLVIATRGSQLALWQSNHIKAILQEQNPGLEVELNVIVTTGDRIQDKA
LSKIGGKGLFLKELEEAMLQGEAQIAVHSLKDVPTVMPDGLILAAITERE
DSRDALLSEKYANIDALPKNAVVGTSSLRRRMQIQKLRPDLIIKDLRGNV
DTRIRKLKEGEFDAIILAAAGINRLSLLDAVKHVYPISLEEMVPSMGQGA
LGIEAVNDAEVLRIVAGLEDEYSRIETTIERSFVDELEGGCQVPIGVNAS
VLDDGTISIRAVLGLPNGEEMLSDSKITSKKDYENIGREIAAEFIEKGAK
ELLSRAEAMMENK
>Tmden_1173 Thiamine monophosphate synthase
MRLYALCDQDLLDKKGLSLEDFISTAKEKNAEIIQYRNKNADIAFIKQQL
IKIRKMYDGFLIVNDAYELIEFCDGVHVGQEDLMAIDKDIFAAVKIIREV
IKKDKILGISTHNEKEILEANQMDLNYIGLGAYRNTDTKNNVTTVLGEKL
DSLASLSKHYVAAIGGVKESDKFSHVTYHVVGSGLL
>Tmden_0680 Ubiquinone/menaquinone biosynthesis methyltransferase
MQEQEKQNKIVSMFDDIAPTYDTANRVMSMGVDKSWRRKACDLSYGFYAK
DSIDKIVDVACGTGDMMDFWKKRAETNGIAVGEIVGVDPSKGMVNVAREK
FPKFNYHISKATQIPLEDASADILSITYGIRNVVEREAALVEFSRVLKSG
GLVVILEFMKNENPSFLGRIRDFYMNKILPKIGGFISKNLEAYEYLPNSI
ESFSTVENMKKELESAGFEVIYSKSFSMDISTLLIARKK
>Tmden_0875 D-3-phosphoglycerate dehydrogenase
MQKYTIVVCDHIHEAGLEMLQNDKNINFIMAADEDKEKLLTIIESADVAI
TRSSTDVDAKFIAHAKNMKAIVRAGVGVDNVDIAGCSKEGIIVMNVPTAN
TIAAVELTMAHMLSCMRMFPYSHNHLKLDRVWKREKWYGYELKGKKLGVI
GFGNIGSRVAKRAQAFEMDIIAYDPYINPSKVTDLDMVYTKNFEDILSCD
IITIHTPKNKETVNMIDVAEIAKMKDGVVLINCARGGLYNEEALYAGLTS
GKIRFAGIDVFMKEPATNHPLLDLDNVTVSPHLGANTYESQYNIGVQAAE
NAIAAAKGISYAHAMNLPIDESKIPPFVKPFLEMGQTIGFLETQLNQSQI
VTIKVSGQGEIAKYVDSLATFVAVGAMSQISDNTINYVNADFVAKEKGIK
IETEALLDSTVYKNLITIKLTTAEGGTTTISATIFDDNVFRIVSIDGFDI
EVALKGDMIILKNQDVPGVIGNIGSTLAKHNVNIADFSLARNDKKQALAV
ILVDNVISDDTLEELLRIDACSSVQYARL
>Tmden_0541 Ketol-acid reductoisomerase
MALTVYYDKDCNINLIKSKKVAMIGFGSQGHAHAENLRDSGVEVVVGLRK
DGSSWAKAEAKGFKVMTVGDASAYADLIMILLPDENQAEIYKDEIEPNLK
NGATIAFGHGFNIHYGRIHPRADINVTMIAPKAPGHTVRSEFVRGGGIPD
LIAVGQNPSGNTRELALSYASAIGGGRTAIIETTFKDETETDLFGEQAVL
CGGAVSLVQAGFETLTEAGYAPELAYFECLHELKLIVDLMFQGGIADMRY
SISNTAEYGDYVSGKRVINAESKAAMREILKEIQDGRFAKDFILEGQSGY
PRMNAERANAKASLIEQTGVKLRTMMPWIAANKIVDTSKN
>Tmden_0896 Pyridoxal phosphate biosynthetic protein PdxJ
MKLGVNIDHVAVLREARKVNDPDILNALYVATQNGADQITIHLREDRRHI
QDADAYAIMKYSNVGVNLECSINRAILDIVTDLKPHRTTLVPEKREEVTT
EGGLDVVGHEDEIAYAIELLHDYLIPVSLFIDPTIEAVEKSKELGAEMVE
LHTGAFANLYAMLSSSLPHSNHSIKELELPRHELSIRLEKSILAIDEAAK
HAKKIGLEVAAGHGLNYHNVHEMMKIAEITELNIGQSIVARSIFSGLGEA
VKEMKRLTSR
>Tmden_0858 Polyprenyl synthetase
MQRVDSEITRLIKEIDYDEVTNLFNKLQGGKRLRAGLILKIAPTCTTAPL
LGAIVELIHAASLLHDDVIDEATLRRGVASINATDGSKTAVMLGDILYSK
AFSELVAFDKEIAKVISSSVTALSKGEMMDVKMASAFNSDEERYLEMLYL
KTATLIEACAHAAALLAQKDALSHSIYGKNLGLSFQIIDDILDITSDEAT
LGKPAMNDFVEGKCTLPYIYLYQHLGEEDREKLSSLHAKALSRDESIWIR
EMMQQHKTIEKSFALAQKLSNEAMSVIKDDTELVEILQTMIKRSY
>Tmden_0361 Pantoate--beta-alanine ligase
MKIISNPLELKEYLKDEKRSIGFIPTMGALHEGHIALIKKAKEQNELVVV
SIFLNPTQFLKGEDLDKYPKKDEADRQICKLCGVDILFFPHVDGIYGSDE
VSLLAPKIRGFVLEGQSRPSHFNGVLTVVMKLLNIVRPKRAYFGKKDAQQ
LNLISLMVKQLFMSVEIVAVDTVREKDGLALSSRNAYLTPAQRQEALKIA
TSLRSATAMVMRGIFDSELIIANMREILSPLDISYVAIVNREFTELKRVE
IGNSVILVEASLGSTRLLDNIWL
>Tmden_0434 putative para-aminobenzoate synthase component I
MSKTFFETIKAVDGEIFHLSFHQKRYESVLKHFGIKEIQNLSLHVNPPKN
TLYRCRLTYDLSINPHKIEVEYYEYQKREISSLKLVYDDRIVYDLKSTNR
ERLEELYELRESCDDILVVKNSLITDTTIANIAFYDSKNWLTPAKPLLKG
TTRDRLLSENKIYEADIHVKDLKNFSHVALMNAMIDFDIITKNNKEFFC
>Tmden_0568 Glutamine amidotransferase of anthranilate synthase
MILMIDNYDSFTYNIVQYCRELGADLKIIRNDEMSVKEIEALGPQKIIIS
PGPATPNDAGVTLEVIEHFKDKVPILGICLGHQSIAQVFGAKVVRAKNMM
HGKTSLMKRSGDCAIFKDIPQEFIATRYHSLIVDKNFIPDIIEPTAYSQD
DNEIMALKIKDKDIYGVQFHPESIMSEYGHEIIGNFLKL
>Tmden_1188 ApbE-like lipoprotein
MFWLLEAKTTSRTQVIMSTFITIKTDKKNEKYIEDGFEIMKSVDMSLSSY
NKDAKVFLLNKNLHVSLDAYLYEALSLCKYYYKVSYGYFDITVGSITKDL
YRFGEDERVASASELKSAKIDFNALKFNEKEAFIEDGMKVDLGGMGKGFG
VQKVADYLKKMQVDDAIISASGDIRCLSTCKIEVQNPFDEESRLLSFETL
KSDMGISTSGNYNRYILSKENNHLIDPKAKKPQMLFASITLISSLSSASL
DAYATAASVMPTNKAYEFLDTLDVAYIIVQSDKEIVISKNIASYVKNLSN
FSK
>Tmden_0460 Dethiobiotin synthase
MKKRIFITATNTDIGKTYTTKLLLKEFASRGLLVGVIKPIETGVVDGYAD
DGEELLQYVKELNPKLWSLEVEDIVPITYELAAAPFVASNNTPLDLRKIK
IKIEEMEASCDIVIIEGAGGLYVPIDDKYMMIDLLKKLDAVALLVTHCSL
GCINDTLLSKGALEAKEILHVVAFNCKNKDDNFDKISEPYFLKTDFKVFK
VDKDIEKICDVLYNLSDVKR
>Tmden_1476 Methionine adenosyltransferase
MYLFTSEVVSPGHPDKCADIIADSIVDRLIIGDPKSRVASEVFVAGKHII
IGGEVTSKTRVTTEEYKKIVHDALVGIGYDGNPYFTKEECLHPEEVELQV
LLNSQSPDINQGVDKEDGEVGAGDQGIMFGYADIETGNYMPSAITYARVL
MEKVYNFAKENPSKLGVDIKTQVTMDYGKKENFENCKPQKIHTIVVSAPC
VNTMDIKTVRTLIQSLIDEAGLPSELYNKNDCIVHINPTGKYVSHSSLHD
SGLTGRKLIVDSFGGYAPIGGGAQSSKDYTKVDRSGLYAARWIAKHIVAA
GLAKKALVQISYAIGVARPTSIAVDTYGTAIKGVDDDKLSEFVLQNFPLT
PNWITRKFSLDYPSKETFLYADVAARGQVGQSDYPWEKLDELDKFEALK
>Tmden_1228 Uroporphyrinogen III synthase HEM4
MKKIEKLIEHLNLIYYEYDRATHSFILDRSYSNEHVFEELIKITYILSKH
NINFFVDENKSLILNSKNSFSLKIKRVMNSFIQNLKNRSLNIYVLNDKKV
KWAKNLPVIKIETINTTFNISSYDALIFTSKSAVYTLNSYNTEWKSKPLY
VIAPQTAKVASNLGGKIKFVSRENHGDEFADELIPLLKNKKVLYVRGSKV
VSNLVEKLNANDVICDEVIVYQTVCSELKKKIKLPKNSVIIFSSPSTIEC
FLKNVSWDESYKAVSIGHTTQKYFPPYITPVVADTPSLDSCVKKAIELIS
EK
>Tmden_0665 Dihydroneopterin aldolase
MTIHVENLKFKCIIGILDFERVTPQEVIINLNIDYEHIKHFIDYAKVVDF
IKEIMIKNEFFLIEDALKEINLKLNKKFNGIKSINLKITKPSILPECMVS
VSDFVIFES
>Tmden_0157 Sulfate adenylyltransferase, small subunit
MLDTKKLTHLKQLEAESIHILREVVAEFDNPVMMYSVGKDSAVMLHLALK
AFFPAKLPFPLLHVDTKWKFKEMIEFRDKRAKEEGFELLVHTNPEGIEKN
INPFVHGSAVHTDIMKTEGLKQALNKYKFDAVFGGARRDEEKSRAKERIY
SFRDKNHRWDPKNQRPELWNLYNSKVHKGESIRVFPLSNWTELDIWQYIY
LEGIPIVPLYFAKRRPVIEKDGVKIMVDDERMPIEEHEVVKEEMVRFRTL
GCYPLTGAVESSATTLPEIIQEMLLTKTSERQGRMIDNDSSGSMEKKKIE
GYF
>Tmden_1276 hypothetical protein
MEEKNELNDIILNKNSSSAGNKRVILAVATLGIVLIVVVMLMNSITSSST
DNLPQAILPPEPQREIKSVADEPLFEDVTVVQEAGKENISLDEIAQKLKE
ESTKETPKLQSKAEETKQEDVVESKKTESKKLEPKKTVTKEPKPKPQIAA
SGGLYIQVGSFSRYEPNKKFLDSITKLGYEYKFHKVTNNATPLNKVLVGP
FATESEARKALKELRSSVESGAFLTKI
>Tmden_1238 Thiamine monophosphate synthase
MQKYLITSAQFYTQNSDIFYQTLYKQLKKQKPEYVLFRDKTATNYEELAS
VFTLTCKEIGGVKSFVHQDIYLAKALGADGVHLTSKQFCEIELAKSKNLE
VIISTHSHEEVLQAQKLGADAVTYSPIFASPDKGEPKGVNDLEELLSKCK
IKVFALGGIVTNEHVEMISKTKVYGFASIRYFI
>Tmden_1025 Molybdopterin binding domain
MNTIKIGVITASDRASKGIYEDISGVAIQDTMKEYLKSEFEIVYRCIPDE
QEMIEKTMIELSDKQECCLIVTTGGTGPALRDVTPEATQNVCEKMMPGFG
ELMRQVSLQYVPTAILSRQSAGIRGKSLIINLPGKPKSIRECLDAVFPAV
PYCIDLINGPYIETNEEVIKAFRPKV
>Tmden_1216 UbiA prenyltransferase
MPLLFSFSYMDSHDNIYSFLTFILFSILASSIYIFNDLMDINEDRAHPTK
KNRPLANGAVSTKSAKILILLLSFTSLSLSFLLSFDLFVVLLIYFILNIF
YSIKLKHIAILDIFIIATGFVLRLFAGSVVTGINLSMWIILMTFLLAIFL
ALAKRRDDVLLSIDGQETRKNIDGYNLEFVNASMVLMAGVVIVSYIQYTI
SPEVIHRIGTEYLYLTSFFVILGILRYMQITFVEQDSASPTKIIIRDTFL
KLTITLWLISFLVIAKLL
>Tmden_1912 Molybdopterin binding domain
MPKSIKIFIKMTPKTAITPQLCVTILISYISFIPKCYNKNAKRRNMATSI
EEALQIIYKHTAPKSLKIVPIENALGYVLAEDITATHNLPPFDNSAMDGY
AIKADDAQMSLKVKHTIFAGDNSGEELESGFAIKIMTGAKIPIGCDSVVP
IERVQNFDNAITIMDKVKKGSNIRLYAEDIKSGSTLLNKGEKIFAHHVTL
LASQGISHIKVYKKPKVAIFASGNELKMHFESVDAHQLYNTNSPTFFARA
KELGCDVDFIGTAKDSLENIHKHIQSALDSDLIITSGGVSVGDADFTKEA
FGAFGYEIYFDKVDIKPGKPTTFGKCKETLVLNLPGNPLAAALNFEIFAQ
TIILALKGDAAKYIAPLETKMANDYAIKNGKIAVIPGFFDGASFKAHEKF
SPGMIMPLALCNAFIIVDEKCQMLKKDSSIKIISTRFSFNSKEQKELLNR
CRI
>Tmden_0402 Riboflavin synthase
MKLIEGQLKVVNGKKVAIVSTRWNHFIVDRLVEGAKDAFARHGGDEADLT
HVLVPGAFELPMIIDKLLASGKYDAICALGAVIRGATPHFDYVSAEATKG
IAMMSLKHQKPVSFGLLTTDNIEQSIERAGTKAGNKGFEAMTVVIEMLDL
YENL
>Tmden_2047 Dephospho-CoA kinase
MAFKYAIALSGGIATGKSTVASLLSLNGMRVIDADAISHDILDASSLWVR
ENFGDEFVDGVSVNRSKLGTLIFSDNIAKKKLESFLHPKIRAEIEQRSIK
QDSFMFPYLIDIPLFFESGAYDIKESVVVYVPKELQLERFIKRNGFSREE
SLRRIESQMDIEEKKKRATWVIDNSGDLKHLQRECEEFVEKIKAKYLEKK
>Tmden_1540 Putative molybdenum utilization protein ModD
MCSDFSKNYIKTEDLKMDLLFEDAGYFDLTTYGLGIGEKKGVMSFAPKAE
IVLCGVDEVRTILNNLEIQHTFFKKNGEKVMAQEVILECKAEASKLHKAW
KISQNIFEYMSGIATYTHKMVTLAKEVNPNISVSTTRKNFPTAKELMLKA
VICGGGAPHRIGLFDSILIFEQHLNFFSDKAELEKSFKKLKYAFIEKKVA
VEVESFEQALYFASLGADILQCEKMEYETLKKCITLKEQYPHLLLSATGG
INESNIAEFAKCGVDFIVTSSPYHAKPLDIKVTIKEAL
>Tmden_0385 Porphobilinogen synthase
MFQRFRRTRLNSHLRSLVRETNVSVDDFIYPLFVRSGEGIKTEVSSMPGV
FQMSIDEVLKECEDLKKLGLYSIILFGIPDVKDSIGSDSLCEHGIIAKAI
RAIKKAHPEMFVVTDLCFCEYTDHGHCGIIDEKKQTVNNDATLEISAQQA
IVHAKAGADMIAPSGMMDGIIITLREALDGAGYENLPIMSYSTKFASGYY
GPFREVAESTPSFGDRASYQMDPANRREAIAESISDEAQGADILMVKPAL
AYLDIVREIKDATSLPMAVYNVSGEYAMIKFAGMQGLIDYDRVVMETMVS
FKRAGADIIISYHAKEVARMLQK
>Tmden_2086 GTP cyclohydrolase I
MMLHVGENPDREGLLKTPQRVKKAYEFIFGGYKEDPEEILNSALFTSSND
EMVLLKDIEFYSTCEHHLLPIIGRVHVAYIPNGKVVGLSKIPRVVNVFAR
RMQIQEQLTEQIADAIMNTIKPKGVAVVVQARHMCMEMRGVEKINSTTTS
SALRGLFKKDEKTRSEFFSLINSPNGSRY
>Tmden_0668 Nicotinate-nucleotide pyrophosphorylase
MIEDFVKETLAQDVGRGDLYALVEPSVEASAKIVAKSDGVMAGVTYCNVL
AKLENFRVVWNKNDSESFVKGDVLATLSATSHVLLRVERTFLNMLLHASS
IATLTKKYADIIEPYGVKLLDTRKTRPMLRVFEKYATRCGGAVNHRMGLD
DSLMIKDTHLKTIKDLKSYIQKARQKIPFTAKIEVEAETLEIAKEAFKAG
ADIVMCDNMTPSQVQEIVKYRDANFSHVLLEASGNISLQTIENYAKVGVD
AISSGSLIHQANWIDLSMKVD
>Tmden_0404 conserved hypothetical protein
MKRLTKQEALELIKSADFKELGRMATARKKELHPEGITTFVVDRNINYTN
ICWVDCKFCAFYRHEKDADAYVLTFDEIDKKIDELLEIGGTQILFQGGVH
PKLKIEWYEDLVEHIHTKYPTITIHGFSSIEIDFIAKVSHISVEEVLERL
HVKGLASIPGAGAEILSDKVRDIIAPKKIDSEVWVDVHRKAHKLGIMSTA
TMMYGTVESDEDIIEHFDMIRRLQDETHGFRAFIMWSFQGQNTELLRLIP
DMEKPSSNRYLRLLAVARLYLDNVPNIQSSWVTQGPYIGQMALRFGANDL
GSTMMEENVVSSAGAAYTMAKSEMVHLIKDIGEIPAVRNTAYEILEKFA
>Tmden_1189 3,4-Dihydroxy-2-butanone 4-phosphate synthase
MTPTQRVLEAIEEIKRGRMVIMIDDEDRENEGDLVYASAFSTPVHVNFMA
THARGLICVAINRSIATRLALNPMVSSNTSSYETAFTVSVDAKNALTGIS
AGERDDTIKILANPISHADELVKPGHIFPLIAKDGGTLVRTGHTEGSVDL
CRLAGLSESAVICEIIKEDGTMARRDDLDIFGEKHNLKTVFISDIVEYRL
ANERLVSEASVEEIEFFDTKVKKHTFLDHDKIEHTAIVFHKITSVANVRV
HNVIPDIELLLNQKKYHNLISSIEYLKQNSGVLIFINKPTHNDNAAMKEF
GIGAQILKSFGISKMNLLSSSSHTEFVGLSGFALEINEIIDI
>Tmden_0197 Radical SAM
MSYVNNKNLIYKFYSTRSLKGFAKNFLLKSMAGQKMFLYNKNIPRVINIS
FNEHTCMFKCKICPYSQNEVADMYKQKKEMSFETLKNIVSSVPNDSFYSF
DISSIGETLEFKNLAKFISYMKEQKPLVNTIISTNGLLLNEKIARDLIKS
GLDNIQFSLFAGDEDGHKFVTQSDSFTKVKKNIINFKKIKDSLGSKTPFT
QTFMIETKENKHLSNSFVEKWSSFVDKAFIRHMYKMGHPIDGMTPSYEDE
NHKKERYPCVAPWYSTSIISNGDVLGCYMFNWHAKEKESMVIGNINKNTL
SEIYTSKNNQDFRDNQLDLNFKSCEACKDCNLWDAYTNIWEKDSKSYKYS
SLKVFDFFNTKLEYRGG
>Tmden_0254 possible molybdopterin converting factor, subunit 2
MLYLYDGALDVPRILKEWYEQEASSNYGAYIPFVGTVRSEDGIDGLSFDI
YEPILNSWFDAWQKKAKERGAIIKMAHSRGDVMLHESSYIAAVFSPKRRV
ALEFIDEFVEDFKATAPIWKYDLKDAKRIYALNRSTAIKGSGILK
>Tmden_1031 Thiamine-phosphate kinase
MNLENYFISQFKSANIGDDGAFIDGMVYSKDAFFENIHFKTSWMSHYQIG
YKSIMVNISDAVAMNATPKYALLSVAMPKDITKSQMRDLAKGFQDACAKY
GVDIIGGDTISNIKLDITVTIVSKSNKPLMRKGLKRGDLIAYSGTLGKSA
KELKKLMNLGKIHKNSKFVNIFLRDKFIYNNRRFLRVGMDISDGIFSDLQ
KLSLASGVGFRFYKKIQKRVGCSGEEYEMLFGFDRRFKKTLLRRAKLTKT
PINIIAECVRKAYTNRCKSHHFNKN
>Tmden_0998 DNA/pantothenate metabolism flavoprotein
MVIPADLLKGKKILLGVTGSIAIYKSLELVRLFSKAGAEVKVVMSEASKK
FIAPLSFEALSSNMVLDDTNESWANEHNHIKTTQWADLFVIAPATANTIA
KLANAIADNILLESALAYPDLKIIAPSANTNMINNPITKANLKMLAIANY
EIVETQTKELACKSVGNGAMAEPLEIFWHCAKALLRDTFWMDRRVIVTGG
GTIEKIDDVRFLSNFSSGKMASAMATALYCRGADVNLISTKFEPELPLDL
YTIKVESSAEMAEYLNDSIRIAKKGKLSKATLMRDEQIHLIQKKPYLFMV
AAISDYVVSYAQSGKLKKESLGSEWNLQLKENLDILSSIDKKGITTIGFK
AEMDEQNALQNAQKMLEKKSLDAVCLNILKDSSSFATDTNSVDFLSKNKH
QKIALCDKLNIAFEILEHAKNI
>Tmden_0943 DNA-damage-inducible protein d
MKKDIELQHHQTFEEIKQIDKNGNEFWYARALGKLLDYTDFRNFTKVIDK
AKEACVNSGFDVNDHIVEVNEEITHGKGAKNSYPSFALSRYACYLVVQNA
DPSKPVVASGQTYFAIQTRRQELQNDEAFAQLREDEKRVFLRNELKEHNK
QLVETAQLAGVETDLDFAIFQNHGYKGLYGGLDAKGIHEKKGLKKSHKIL
DYMGSTELAANLFRATQTEEKLKRDNIHGKTKANQTHYEVGKKVRETIAE
LGGTMPEDLPTPKESVSKIEKSHKSLEDKKS
>Tmden_1341 Riboflavin kinase / FAD synthetase
MTDIRNSTAIAIGGFDGMHIGHQQLFRALDEKSTIVVIETGYANLTPKRE
RESFSHYPLLYLELNEIRHLNGEEFIAFLKDKFPKLQKIVVGYDFHFGKD
RKYSFNNLKELFDNEVVVVNEVTLHGDSVHSHKIRAKLQIGDIVGANAFL
GHNYTIKGTLVSGQGIGKKELVATINLEAKEYLMPKEGVYVTLTRIDDEE
HFHPSVSFVGHRITTDGSFALESHILDGEVICKERATISFVSFIRENRKF
DSLDELKKAIHKDIATASKELKFLQL
>Tmden_0253 Thiamine S
MVRVEFLGPIQKESLELNITNLNELSEILKKDETMHEWLENSAVAVNDTL
VSSRDFALKDGDRVALLPPVCGG
>Tmden_1894 Aminotransferase, class I and II
MYYTNELQALKRASRYRSREVVDTSILDFASNDYLGLSHNKALHEATCKR
LSNMPLHSSKASLLVNGYHQIHKDFEDALCVANGFEDGVILGSGFNANIA
LIEALVRSKDVLFMDEKYHASGILATNFKKINVKFFKHNDMQELQKLLKT
TKAQRKIVAVEGIYSMDGDMVDRRVFELCDAYDAILIMDEAHSSGVVGEH
LMGIYDHYNISIKPNHIKMGTLGKAYGSFGAFILASSHIVEYLINRAKPI
IYATSLSLYDTLLAHNALKYILENLDSLKEEIRKRQEIVYDELGIKMDAL
ICSVVIDDNEKVIKIRDELKKLGFSVGGIRQPTVERAIIRLIARIGESSE
DLRALCRSLDKIQK
>Tmden_1569 Folylpolyglutamate synthetase
MNFLEYLNAKPLYYDEIDYTRMPRIYKKIKESLVTPKIIHVIGTNAKGTT
GRFLANALHAKGLSVGHYSSPHILKFNERVWVDGANATDVELEEAHRELQ
KILTIEDAASLSYFEYTTLLSMIIFKECEYVVMEAGLGGEHDATAVFDKV
LTLVTPIAYDHEALLGSSIEQIATTKLNAIQNSAIIATQTYPQVYSIAEQ
IASQKGLNIYMVNDFIKELDREKINHIANTLSLIPYLRDNLTLSIAALKF
LKIEYETYDFKNPPLFGRVSKISKNITVDVGHNVLAAQGILKALHGDKYI
LVYNSYKDKNYKEILSILKPIILHVEIITIDEQRIESIETIKSTLKNLKI
KYKTFKETKPEYKYLVFGSFSVVERFLREYHE
>Tmden_0111 Cobalamin-5-phosphate synthase CobS
MRDIFKGFALAVSMLTTVPFFKVHDFFKGINGYAVMFYPLVGFLLGSALW
GVQSLLSPFAPSFHLGIIIFVLWVLLTGALHLDGLSDTVDGLYVAKEKAL
KVMKDSHVGGMGMIISATFLIAKASSLAHFEAFYLLPIILMLSRLNIVLA
IYLYPYVTPNGMNTLAKEELTKKQMFIALFYSLILVAFFNMWLALATALL
VLFVIKSFFIKCYGGFTGDIYGFSIEVTELILLNVLLFSL
>Tmden_1687 S6 modification enzyme RimK
MRIYILSRNKELYSTKRLVQAAQERGWEARVIDYLKCSIEIMKDELKVNY
LGKELPTPDAIIPRIGASRTFYGTAMVRHFEMMDVFSATGSLAIKRSRDK
LRSLQILSKNGVDMPKTVFASNKSNAKDVIELSGGAPLVLKILEGTQGVG
VVLVDSEKAAKSVLDAFYGMDVNLLVQEYIEEAGGADIRVFIVGGKIIGA
MKRQGAEGDFRSNLHQGGSATAHKLTKKEKETALAAAKAMGLGICGVDMI
QSNRGPLVMEVNSSPGLEGIEKSTKIDIAGKIMEYIAKNIDPKCKINPEK
RKIKKDSIGA
>Tmden_0116 ABC transporter-related protein
MIELKNLTCSYGKTTILKDVNLKITSHLSILGANGSGKSTLARALCALID
YDGEIIIDSVDLKSLSNKTRAKTISYVPPKLELYDSFITLREFVLLGRFP
YKKSFFDYSAKDKKIAEKYISLLGLEHLSECSILSLSSGQQQLSLMASAL
CMESKIMIYDEPTANLDPYNSKIVANYIKNLKNTHQIILITHDLHLASFI
GSDIAFIKEQHVAFYGDTFFNDKILEELYGVSFNSLVLEYE
>Tmden_0420 L-aspartate oxidase
MRYDVIIVGAGVAGLYAATHIPKSKKVLLINKRETFKCNSFYAQGGIALA
IDAEDIPLHVQDTLDAGAGLCSEEAVRVLSESSRAIIDDLINRGFEFDRD
KDGNLLYTKEAAHSKERILHAGGDATGRHMHYFLLQQNPHPMLTDARVVD
LLIKDGECYGVTVLDHRESRNIYADNVILASGGVGSLYEFHTNAPCISAD
MQGLCVMKGIELSDMEMMQFHPTVFVDSDSAQKLLLTEALRGEGATVEDE
AGRRFLFDYDERGELASRDIVSKAIYDHNKKTKMQTYLSFKNFDHVYFTK
RFPNLYKSLQLLGYDVPKQRVPISPAFHYAIGGIKTDVNGAVPSIKSLYA
IGEVASTKVHGANRLASNSLLEGLVFGKRAVEHILKKKNSKKELFFEVSS
EIMSLKEDKEKKNLLRRIMWEKVSIVRTKNGLNSALHQINALLNEKIGKL
LKFRLLTAREIVLGALARDESIGVHFIQKDDND
>Tmden_1141 Acetolactate synthase, large subunit, biosynthetic
MQISGAQIVIEALIAEGVDTVFGYPGGAIMNVYDEIYKQNNFKHILTRHE
QAAVHAAEGYSKASGKVGVAMITSGPGFTNAVTGLADAYMDSIPLVVISG
QVPMSLIGTDAFQEIDAVGISRSCTKHNYLVTDAKDLARVLKEAFYIASS
GRPGPVHVDIPKDVTAQLAEFDYSIELDLETYKPHTKGNPRQIKKAMEAI
SKARRPIFYLGGGIINSNAAYEVRELVKKTGIPAVETFMARGTLSHDDEL
LISMLGMHGSYAANMAMSETDLVIGLGARFDDRVTGKLSEFAKNAGVIHV
DIDPASISKLVIADYPIVGDVKNVVNEMIELSSSINPAKYASWRETIRNF
DELHPLTYHEDTDRLKPQWVIQRVGELLGDSANISTDVGQHQMWSAQFYP
FTRPRQFISSGGLGTMGFGFPAAMGVKVASPDKISINFTGDGSILMNCQE
LMTAVEKKLPVINIILNNNYLGMVRQWQTLFYDKRHSETDLSVQPDFVKL
AEAFGGIGFRVTTKEEFDAALKEAVEKNIVTFIDVVVERLENVMPMVPAG
GSLFNMMLLEKKEKK
>Tmden_0334 Aspartate 1-decarboxylase
MTIEMLYSKIHRATVTDANLNYVGSITVDEELLEASMLRVGQKVEILNIN
NGERFSTYIILGERGKRDICLNGAAARKVHKGDKIIIVAYATYDEKELQN
YKPRVVLVNDNNDIEEILESI
>Tmden_0845 5-formyltetrahydrofolate cyclo-ligase
MALTKVIFRQNCLNKIKNSSKHNCLYKNKKISNQLIKELKKFKNKKILFF
ISLPFEADTAKIIKQIRKKYKIFVPFMQGESFKMVPFRLPLKKKKFGIYE
AGNSLRDIKNIDVAIVPVVGVDGNLQRVGFGKGMYDRFFEKLKKRPYTIF
IQSEFCFTKELICDDYDITSDLIITPNIRVQNRNIDKMRK
>Tmden_0688 7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK
MFIERKLNDSLTIYKNLRFYKKEQKSFHRYRVTIGIGGNVGDVKRRFAHL
ETYFKRDKRVEFLQKSLILKNPPFGFMNQDDFFNSIIILKTSMQPMLFLN
YLMRVEKKFGRKRSFANAPRTLDLDIIFFDERVVKKERLSIPHPEYSKRV
SVLIPLKGLKK
>Tmden_1113 Methylenetetrahydrofolate dehydrogenase (NADP+)
MQLLDGKALSAKIETTVAKEVKELKNSTNLVPGLAVILVGQDPASAAYVN
MKKKACDRVGFYSVTHEMPSDISQSAIENTITMMNNNPNIDGILIQLPLP
TQIDTTKILELVEPSKDVDGFHPYNVGRLTTGLDGFVPCTPLGVMELLKE
YKIDVKGKNCVVVGASNIVGKPMAALLLNANATVEICHIFTDDLKKHTLA
ADMIFVGAGVINLIKEDMVKGGAIIVDIGINRAESGKLVGDVDFENVAKK
CSFITPVPGGVGPMTIAMLLSNTLKAAKAHAKENE
>Tmden_1777 Methionine adenosyltransferase
MTKEEKTLKEYIFTSESVTEGHPDKMADQISDAILDYIIEHDPSAHVACE
TLVSNGFCVIAGELKTTAYAPMQEIVRRVVQEIGYTDATYGFDYRSAAVL
NGIGEQSPDITQGVTLLDGEIGAGDQGLMFGYACRETDVLMPLPIYLAHL
LTRRLAEVRKEGIIPYLRPDGKAQISVKYIGDKPVSVEAVVVSTQHAPEV
SQEKIREDVIRDVIRAVIPAELMSEKTLFHINPTGKFVIGGPQGDAGLTG
RKIIVDTYGGSCPHGGGAFSGKDPTKVDRSAAYACRHVAKNLVAAGVCDR
VTIQIAYAIGISAPVSIMIDTHNTAIVEEKKIESCVKELFDLTPKGIIKS
LDLLRPIYRKTAVYGHFGREEEGFTWELTNRVEDIKKYLKIN
>Tmden_1062 Molybdopterin-guanine dinucleotide biosynthesis MobB region
MKKRLAVAFTGPSNSGKTTLILKVARKLIHEYKMDVAIIKHDPKDKARFD
VEGKDSYKFADTGAEVIVTSPNRTTYFSQRQKELDEMIRLFDKFDILLVE
GLKNLPLPRISVFRDSLDAEYFPYMNALATDGSIDISRYDFPKNVAILDI
NSCQDVIEWILKNAKEV
>Tmden_0384 GTP cyclohydrolase II
MNIEISEVANLPSRFGDFKVKVFKVGCKEHLVIFKEPIDEIPIVRVHSEC
LTGDAMGSLKCDCRDQLEHALMLASKTNGMVIYLRQEGRNIGLLNKINAY
ALQDQGLNTIEANHQLGFDADERTYEIVPFILEHFGIKRIKLLTNNPKKV
LSLSGIDIVERVPIIMKSNPHNEGYLNVKKESMGHLL
>Tmden_1109 Glutamate-1-semialdehyde-2,1-aminomutase
MSIDNSLKAFKEAQNLIPGGVNSPVRAFKSVGGTPLFIANGSGAYLTDID
GNRYVDFVQSWGPLLFGHRDESIESAVIEAVKHGLSFGAPTQAESDLAAL
VISMFDSIEKIRFVSSGTEAVMSAIRLARGYTNCDDIVKFTGCYHGHSDS
LLVQAGSGAATFGNPSSPGVPADFTKHTLLAEYNNIESVKKCFSDSKDVA
CVIIEPIAGNMGLVPADKEFLRELRELCDANGALLIFDEVMSGFRASVHG
AESITGVKPDIVTLGKVIGGGMPVGAFGARAEIMAKLSPEGPVYQAGTLS
GNPVAMAAGLAAITKLKQNGQIISVLNSRATRLVEGMQEAAKTYGIAMQI
DTRGSMFGFFFNEKPVKNFADACNSDEKLFALFHSKMLKEGFYFACSLYE
TGFISTAITDEMIEDTIKASAKVFKEITNV
>Tmden_1989 Uroporphyrin-III C-methyltransferase-like
MGKVHLTGAGPGDIELLTIKALRVIKEADVIIYDRLANPDILQEAKNGCE
FVYVGKEDGRHIVPQDDINEVIYQNALKHENVVRLKGGDPFVFGRGGEEA
LYLRDRGISFDVIPGITSAISAPAYAGIPVTHRGVSVSFRVVTGHESPNK
KESQIPWETFKTDDTIVFLMGLHNLPKISKKLMEIGKPKNYPCAVISKGT
TKEQSVVVGTLEDIVAKTKDVPTPALIVVGRVVELREQLQWFEGNE
>Tmden_0918 Ferrochelatase
MKKEAIILLNMGGPNNLEEVEVFLTNMFNDKNIITVKSSLLRKLIATLIT
FSRTEKSQEIYNQIGGKSPIVGHTKKLVEKLQNRVGENIIVDFAMRYTPP
FVSEAIERLSDKNIEKIYLIPLYPQYSTTTTKSSLEDFEEQYHLSSGDAI
LVEIKHFFQNKNYNMAILERIKERVSLEEMSEFDLIFSAHGLPLKVIQRG
DTYQLHVQKHISILEQMMQKEGMTFKNIHLAYQSKVGPMEWLKPSLEDKL
REIKNRKVIIFPIAFTIDNSETDYELEIEYREVAHEMGYEEYRVCRCPND
SEYFVEALVDIYAKMR
>Tmden_1877 Branched-chain amino acid aminotransferase I
MDAAKYIWMNGKFVSWDDAKVHVLSHTLHYGNGVIEGTKAYKTQKGYAIF
RLNDHTKRLKESAKMTIMEIPYSVEELNKAQIELVAKNEFKGDNVYLRPF
AFLGYGVMGVYHKHAPVETVVAAWEWGAYLGEEGMKKGIKLKIVSMSRPA
NTSNMGKAKAVANYLNSQMAKYEAIDCGYEEALLLDDQGYVAEASGASFF
MVKNGVLITPPNDNSLESITQKTVIELATDMGIKVERRRLSREDVYVADE
AFLTGTAAEITPVRHVDGRDIGCGARGEMTEKLQSKYFDVVFGRDKKYEH
YLTYVN
>Tmden_0107 Nicotinate-nucleotide-dimethylbenzimidazolephosphoribosyltransferase
MGRADFLLAACVTLTCEIEGITQAGIAGLIPLTPTLDAEFITNSKVFSLD
EIAETPSGVPTPAIITRAVHNLTPFSSIEILDLGLTKLPQNSTYHTFGIA
PSDSIATGANIDAKTIFEKGMRAGRSYELKGSYLILAESTPSGTTTAAAT
ALALGYDCKDDFSSSFLHVPKNIKQETIKSALSLINDDMTNFEKLSYVSD
NMLLFCAGFLLEASRRFHVVLAGGTQMASVLLIADKLREDVLMRIKSDNV
TLATTSWIANDKNSDIAHILSLLSYKPHALYTTFSFKETSIPLLKKYDDG
EAKEGVGAGAALGYAHANGIENEKLLREIESILYNS
>Tmden_0169 Biotin synthase
MNQKIFLCSICNINSGTCNEDCKFCSQSVRYKADIDRYKQKEISLILKEA
QDAYSNGALGFCLVTSDKGLNDKTLNFVCSIAEVLSKELPELRLIACNGT
ATIEQLLTLRASGIKAYNHNLETSREFYPKICTTHSWDERYETCQNINNA
GLVLISGGIFGLGEREEDRVSMLKSLDSLKPTSVPINFYHHNEALELSPN
PLSVDEALSLIKLTRAMIPDAQRIMVAGGRELMFGDRESEIFANGANSIV
IGNYLTTSGKAMQRDLEMLKSLNLDVASSVK
>Tmden_0679 Riboflavin biosynthesis protein RibD
MVIDENFYMRLALNEAWKYQGLTYPNPAVGCVIISKSGEILALEAHKRAG
LPHAEVEALKSAYIVLSGDKKILELTESAQIHNYLLENHNDYFKDATIYT
TLEPCSHIGKTPSCATLISKLNIKKLIVGSLDSNEIASGGNKVVNDAGVE
IKYGVMQKECDELLLPFWLWQKDKFVFFKWAQRLNGTVDGGIISSSKSRT
KVHAMRDVCDLLVIGGNSVRVDRPTLDARLVNGRAPDILIVSKSDDFDKT
IPLFSVKNRDVVISDNFDILKNYKNIMIEGGGGMFEYSKDVVNYHLTFIS
PLIGGDDGFTCSSEKFKILNLDQDEQDIIMWMKREL
>Tmden_1913 6-pyruvoyl tetrahydrobiopterin synthase-like
MIIRKLFKFENAHVVRGCSTLRCRSSIHGHSYKVELLFESNFLDNAQMVY
DFGLMKQNMKAIIDSFDHSITLWDKDEAEYIASMQKHSQRWVLLPLSPSA
EQFSRLFFVLIDKLLSLTTSVNGEKEVKLYSVIVHETDTGYAQAFKEDAY
SKNMGIVNIDEIIFSDTIKDDWADRDFWDKMKKDKRFLNPTTV
>Tmden_0601 Aminotransferase class-III
MTYQDRLLKVIPGGAHTYSRGYDQYPLNAPQILKRGKGAYIYDEAENEFL
DYGMALRAVNLGYANDEVNQAAIKQIEYGNNLTKPSLIELEAAELLVDMI
DSVDMVKFTKNGSTATTAAVKLSRAYTGRTLIARCVEQPFFSYDDWFIGS
TPITKGITKNDIENTKLFNYNNIESLEKLFSEFPNEIACVMLEPSSTEHP
KDNFLHKVKELCHKNGAVFILDEMITGFRWHLKGAQHYYDVKADLCTFGK
AMANGFSVAAIAGKREIMQLGSIEFIGQERLFLLSTTHGAEMSGLGAFVE
TMKFMKEQRVVEHMWNYGEKLIALMNESAKKYGIEKNFIAGGIECSPYYL
TFDKDGANSLGLRTLFSQEMIKNGVLMPWIALSYAHGDKELEITKNALEK
TFEVYRKAVDDGYEKYLVGEAIKPVFRKFN
>Tmden_1125 Coenzyme A biosynthesis protein
MGIMKKIALYPGTFDPITNGHFDIIERALNLFDEVIVAVALSADKKPMYM
LDERIVMVKAALMGLKNVTVVGFDNLTVELAKSNNATVLIRGLRAVSDFE
YELQLGYLNNSLDEEIETVYLMPKLQHAFISSSIVRNLLKFNAKTEHLVP
KEVQKIIAEKKSCILQ
>Tmden_0255 Molybdopterin binding domain
MSLLSYETSQTMLSLLHVNSSRSQNVPLSASLGRVLSEDIIAKHNDPEFP
TASMDGYAVMHSDLELGKIAVVGYNPAGSDEQRTIKSTECIKTFTGSMMP
HGADTLIQIENVTLEDGAIIINESVPKGSSVRPIGEGYRAGDVLIQKGTK
IGFAEIGVMAALNHVMVKVALKPRVAVISTGSEILDLGEHSDNPSQIRSS
NNYTLAALFEQAGAEVIQLGTVGDDKSLIMQTFQDALLSADIVVSTGGVS
VGDYDFVKDIVPRIGAEVLFKGVAIKPGKHILVAQKEDKFILSLPGFAYS
STVTAILYVLPLIAKMLGKESAYRMVAAKLSEEFKKRSRLTEFTACNVVV
EDGEYFINFKDKKVGSSAILTNMLNECALMISGEDDGDLQEGTFVNVILI
QNF
>Tmden_0895 4-hydroxythreonine-4-phosphate dehydrogenase
MSKVRIAISVGDLNGVGIEIAIKAHEEVSKLCAPLYCINSYMLNQASTLL
NYKIPSNFEISEVGGEFAVKKGCVDKDSGRYSYDSFIHAISLCEQKKADA
VVTMPIHKEAWMLAGLKYKGHTDLLREHFKRDAIMMLGCQKMFVALFSEH
IPLKDVASSIKYKKLKQFFLDFNNSVPNERVAVLGLNPHAGDNGVLGNEE
LIITKAIKSANKKVCFEQFIGPLVPDIAFTPHIREKFKYFIAMYHDQGLA
PLKALYFDESINVSLNLPIIRTSVDHGTAFDIAYEKKAKTLSYINAIKSA
IALGERL
>Tmden_0475 Deoxyxylulose-5-phosphate synthase
MNIKASRIKELETLCKNIREEILRVVSKNGGHLSSTLGATEIIVAMHEVF
DSKKDPFIFDVSHQSYAHKLLTGRWDKFDTLREFNGLCGYTKPSESEHDY
FVAGHSSTSISLGVGAAKAIALKGEQNSRIPVIMIGDGSMTAGMVYEALN
ELGERKYPMVIILNDNEMSISKPIGAISRILSSAMASPFYQNFKKHTENF
VDNFGDGARYIAKRMEESLKLITPGIMFEEMGIDYIGPVDGHNIASLIEI
LQKAKELKKPVIVHAQTLKGKGYEIAEGKDEKWHGVGPFDLDSGAASKKS
SAKSATQIYAEALLHLAKNNDKIVGATAAMPSGTGLSELIELYPNRFWDV
AIAEQHAVTSMAALAKEGFKPFCTIYSTFLQRGYDQVIHDTCLMNLPVVF
ALDRAGIVGEDGETHQGVFDVSFLRAIPNMTLFAPRDEKSFHQAMAFAAQ
YQFPCSLRYPRGSFTQTSLPESSPFELAKSQLLQSNKGDVLFIGYGNGVG
RAYETSKLLEEKISILDLRFIKPLDKEMLRDMATKHNKWFIFSDSAKMGG
VGSAILEFFADEKILHVELESFEYEDSFITHGKTKDVEESLGLLPAQLAQ
KVKALI
>Tmden_1535 UBA/THIF-type NAD/FAD binding fold
MRYERIKSLLGDDFLKLQNAKILLLGVGGVGGHCLDCLCRSGVSDITIVD
FDTYDVSNQNRQLWSELHEGEIKVEALKKHYPDVEIINARIDEEWIKNFN
FDEYDVVLDAIDDIKAKLALAQKCYKKLISSLGSAKRLDPTKVHVDDIFK
SYGDKFGSKIRYELRKRGFKKKYKVVFSSEEAQVKDKGSFVGVTATFGLV
MCSEAVKMIQEKKENPLKCRGIIGDGCGGGRDFFIKNETLFAYDESSKES
ITLLEEIKNAKKISKSGCIITIECKNQKIEFDLSQMRVISLL
>Tmden_0667 Quinolinate synthetase A
MELTTQQLKEKINEYKKKLSVTVVAHFYQRDEVFEMGDITGDSLELAQKT
MADNSEFVVFCGVGFMGQSVKVLSPNKRVVMPKAACCAMATMIDGMQFDA
SIKALNEAGIQNENILPITYINSNADVKAKVGEMGGMVCTSSNAKKIITT
ALMEGKKILFVPDRCLGQNIANQMGLKSCVIGDGSNVADADIICFNGFCS
VHQLFSVDDIKFYRKKYPGILIAVHPECDPAICNAADFVGSTSQLIKYIK
DLDENQKVAVGTEFNLVNRLRSKNTYVLSSTKPECPTMNETTLRDVYDVL
KSIDDGAPLNEIHIDENTQKWAKIALDRMMAL
>Tmden_2019 molybdopterin-guanine dinucleotide biosynthesis protein A (proteinfa)
MLFDTPCIIFAGGKSSRMGEDKALLPFGSYDTLVEFQLYHLSKIFKTVYI
SCKEKSKFNFEAAFIEDIKTLPLYAPTAGFISVYNHLKSDNFFAISVDTP
FITRSIIEKLLHVDKNTHDATIAKVNGLIQPMCGVYHRSLSEKFSQMLQN
NSHKLGYLLKNSNTFYVEFEDEKSFFNLNHPHEYQEALALLNS
>Tmden_1679 3-methyl-2-oxobutanoate hydroxymethyltransferase
MAKKMTITSIKKSKGVHPLVMITAYDALFARLLEPSADMILVGDSLNMSF
AGRDDTLSATLSQMIYHTNAVAKGAKNSFIICDMPFGTYTNRDDALKNSI
KVFQESSADALKIEGGEDKAEIISHLCSNGIAVCGHIGLLPQAFRSEGGY
KVKGKTDEERIQLIRDAKAIEKAGAFCMVIEGVKADVAAQVAASVKIPVI
GIGAGRDVDGQVLVFSDMLGLFEEFTPKFVKKYLDGASLVKEALKSYADE
VKTRAFPQDIHTY
>Tmden_0634 Uroporphyrinogen decarboxylase HemE
MSKIFVDACFGKETPYTPVWMMRQAGRYLPEYMRVRAEAGNFLNLCHDPK
KACEVTLQPVDIVGVDAAILFSDILVVPLEMGMDLKFVTGEGPKFDDPIK
NEADLDRLFGGDEAASKLTYVYDTIKLIKEQLAEDKALIGFTGAPWTLAT
YMIEGEGTKTYNICKKMMYSNPKLLHKILSKVTEVVKFYMEKQIEAGIDV
VQIFDSWAAAIEPSKYDEFSWKYMVEIADYLKAKYPHIPIIMFPKGIPAF
LDKVYGNFEVFGVDWSTPMDLAKEKLGERYVLQGNMEPCRLYSKEETTES
VESIQKIMGGKRHIFNLGHGILPDVPVENAKHFIKECHRVSKK