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# Escherichia coli K12, K-12

>b1336 abgT, aminobenzoyl-glutamate transport protein
MPMSMSSIPSSSQSGKLYGWVERIGNKVPHPFLLFIYLIIVLMVTTAILS
AFGVSAKNPTDGTPVVVKNLLSVEGLHWFLPNVIKNFSGFAPLGAILALV
LGAGLAERVGLLPALMVKMASHVNARYASYMVLFIAFFSHISSDAALVIM
PPMGALIFLAVGRHPVAGLLAAIAGVGCGFTANLLIVTTDVLLSGISTEA
AAAFNPQMHVSVIDNWYFMASSVVVLTIVGGLITDKIIEPRLGQWQGNSD
EKLQTLTESQRFGLRIAGVVSLLFIAAIALMVIPQNGILRDPINHTVMPS
PFIKGIVPLIILFFFVVSLAYGIATRTIRRQADLPHLMIEPMKEMAGFIV
MVFPLAQFVAMFNWSNMGKFIAVGLTDILESSGLSGIPAFVGLALLSSFL
CMFIASGSAIWSILAPIFVPMFMLLGFHPAFAQILFRIADSSVLPLAPVS
PFVPLFLGFLQRYKPDAKLGTYYSLVLPYPLIFLVVWLLMLLAWYLVGLP
IGPGIYPRLS
>b3475 acpT, protein involved in phosphopantetheinyl transfer and holoACP synthesis
MYRIVLGKVSTLSAAPLPPGLREQAPQGPRRERWLAGRALLSHTLSPLPE
IIYGEQGKPAFAPEMPLWFNLSHSGDDIALLLSDEGEVGCDIEVIRPRAN
WRWLANAVFSLGEHAEMDAVHPDQQLEMFWRIWTRKEAIVKQRGGSAWQI
VSVDSTYHSSLSVSHCQLENLSLAICTPTPFTLTADSVQWIDSVN
>b0511 allP, putative allantoin permease
MVGGFFILGLSTFSIMLAIILSAFFIAAVMVLNGAAGSKYGVPFAMILRA
SYGVRGALFPGLLRGGIAAIMWFGLQCYAGSLACLILIGKIWPGFLTLGG
DFTLLGLSLPGLITFLIFWLVNVGIGFGGGKVLNKFTAILNPCIYIVFGG
MAIWAISLVGIGPIFDYIPSGIQKAENGGFLFLVVINAVVAVWAAPAVSA
SDFTQNAHSFREQALGQTLGLVVAYILFAVAGVCIIAGASIHYGADTWNV
LDIVQRWDSLFASFFAVLVILMTTISTNATGNIIPAGYQIAAIAPTKLTY
KNGVLIASIISLLICPWKLMENQDSIYLFLDIIGGMLGPVIGVMMAHYFV
VMRGQINLDELYTAPGDYKYYDNGFNLTAFSVTLVAVILSLGGKFIHFME
PLSRVSWFVGVIVAFAAYALLKKRTTAEKTGEQKTIG
>b0425 apbA, 2-dehydropantoate 2-reductase
MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVETDGSIFN
ESLTANDPDFLATSDLLLVTLKAWQVSDAVKSLASTLPVTTPILLIHNGM
GTIEELQNIQQPLLMGTTTHAARRDGNVIIHVANGITHIGPARQQDGDYS
YLADILQTVLPDVAWHNNIRAELWRKLAVNCVINPLTAIWNCPNGELRHH
PQEIMQICEEVAAVIEREGHHTSAEDLRDYVMQVIDATAENISSMLQDIR
ALRHTEIDYINGFLLRRARAHGIAVPENTRLFEMVKRKESEYERIGTGLP
RPW
>b0774 bioA, 7,8-diaminopelargonic acid synthetase
MTTDDLAFDQRHIWHPYTSMTSPLPVYPVVSAEGCELILSDGRRLVDGMS
SWWAAIHGYNHPQLNAAMKSQIDAMSHVMFGGITHAPAIELCRKLVAMTP
QPLECVFLADSGSVAVEVAMKMALQYWQAKGEARQRFLTFRNGYHGDTFG
AMSVCDPDNSMHSLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAA
HRHEIAAVIIEPIVQGAGGMRMYHPEWLKRIRKICDREGILLIADEIATG
FGRTGKLFACEHAEIAPDILCLGKALTGGTMTLSATLTTREVAETISNGE
AGCFMHGPTFMGNPLACAAANASLAILESGDWQQQVADIEVQLREQLAPA
RDAEMVADVRVLGAIGVVETTHPVNMAALQKFFVEQGVWIRPFGKLIYLM
PPYIILPQQLQRLTAAVNRAVQDETFFCQ
>b0775 bioB, biotin synthesis, sulfur insertion?
MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKT
GACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGA
AWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYY
NHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVK
DRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVA
RIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDK
DLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL
>b0778 bioD, dethiobiotin synthetase
MSKRYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGSEKTPEG
LRNSDALALQRNSSLQLDYATVNPYTFAEPTSPHIISAQEGRPIESLVMS
AGLRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKL
GCINHAMLTAQVIQHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPL
LGEIPWLAENPENAATGKYINLALL
>b0776 bioF, 8-amino-7-oxononanoate synthase
MSWQEKINAALDARRAADALRRRYPVAQGAGRWLVADDRQYLNFSSNDYL
GLSHHPQIIRAWQQGAEQFGIGSGGSGHVSGYSVVHQALEEELAEWLGYS
RALLFISGFAANQAVIAAMMAKEDRIAADRLSHASLLEAASLSPSQLRRF
AHNDVTHLARLLASPCPGQQMVVTEGVFSMDGDSAPLAEIQQVTQQHNGW
LMVDDAHGTGVIGEQGRGSCWLQKVKPELLVVTFGKGFGVSGAAVLCSST
VADYLLQFARHLIYSTSMPPAQAQALRASLAVIRSDEGDARREKLAALIT
RFRAGVQDLPFTLADSCSAIQPLIVGDNSRALQLAEKLRQQGCWVTAIRP
PTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGNG
>b3973 birA, biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor
MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLRDWGVDV
FTVPGKGYSLPEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGE
LKSGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGPAAAIGLS
LVIGIVMAEVLRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQ
IVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAAMLIRELRAAL
ELFEQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLL
EQDGIIKPWMGGEISLRSAEK
>b3966 btuB, outer membrane receptor for transport of vitamin B12, E colicins, and bacteriophage BF23
MIKKASLLTACSVTAFSAWAQDTSPDTLVVTANRFEQPRSTVLAPTTVVT
RQDIDRWQSTSVNDVLRRLPGVDITQNGGSGQLSSIFIRGTNASHVLVLI
DGVRLNLAGVSGSADLSQFPIALVQRVEYIRGPRSAVYGSDAIGGVVNII
TTRDEPGTEISAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDYAHTHGYDV
VAYGNTGTQAQTDNDGFLSKTLYGALEHNFTDAWSGFVRGYGYDNRTNYD
AYYSPGSPLLDTRKLYSQSWDAGLRYNGELIKSQLITSYSHSKDYNYDPH
YGRYDSSATLDEMKQYTVQWANNVIVGHGSIGAGVDWQKQTTTPGTGYVE
DGYDQRNTGIYLTGLQQVGDFTFEGAARSDDNSQFGRHGTWQTSAGWEFI
EGYRFIASYGTSYKAPNLGQLYGFYGNPNLDPEKSKQWEGAFEGLTAGVN
WRISGYRNDVSDLIDYDDHTLKYYNEGKARIKGVEATANFDTGPLTHTVS
YDYVDARNAITDTPLLRRAKQQVKYQLDWQLYDFDWGITYQYLGTRYDKD
YSSYPYQTVKMGGVSLWDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQ
TAGREYTLSGSYTF
>b1711 btuC, vitamin B12 transport permease protein
MLTLARQQQRQNIRWLLCLSVLMLLALLLSLCAGEQWISPGDWFTPRGEL
FVWQIRLPRTLAVLLVGAALAISGAVMQALFENPLAEPGLLGVSNGAGVG
LIAAVLLGQGQLPNWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGV
ALGIICSALMTWAIYFSTSVDLRQLMYWMMGGFGGVDWRQSWLMLALIPV
LLWICCQSRPMNMLALGEISARQLGLPLWFWRNVLVAATGWMVGVSVALA
GAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASALLLADIVARLALAA
AELPIGVVTATLGAPVFIWLLLKAGR
>b1709 btuD, ATP-binding component of vitamin B12 transport system
MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLARMAGMT
SGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFATPVWHYLTLHQHD
KTRTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANP
AGQLLLLDEPMNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHA
HRAWLLKGGKMLASGRREEVLTPPNLAQAYGMNFRRLDIEGHRMLISTI
>b1270 btuR, cob(I)alamin adenolsyltransferase
MSDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTAAFGTAT
RAVGHGKKVGVVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWDTQNRES
DTAACREVWQHAKRMLADSSLDMVLLDELTYMVAYDYLPLEEVVQALNER
PHQQTVIITGRGCHRDILELADTVSELRPVKHAFDAGVKAQIGIDY
>b0613 citG, orf, hypothetical protein
MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAH
KDMALEDFHRSALAIQGWLPRFIEFGACSAEMAPEAVLHGLRPIGMACEG
DMFRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCR
GLTDRELRTNNSQLTAGQRLYQQLGLTGARGEAEAGYPLVINHALPHYLT
LLDQGLDPELALLDTLLLLMAINGDTNVASRGGEGGLRWLQREAQTLLQK
GGIRTPADLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI
>b3974 coaA, pantothenate kinase
MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINEDLSLEE
VAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVG
KSTTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPES
YDMHRLVKFVSDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEG
LNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQTWYINRFLKFREG
AFTDPDSYFHNYAKLTKEEAIKTAMTLWKEINWLNLKQNILPTRERASLI
LTKSANHAVEEVRLRK
>b3634 coaD, phosphopantetheine adenylyltransferase
MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEE
RVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEM
QLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENV
HQALMAKLA
>b1992 cobS, cobalamin 5'-phosphate synthase
MSKLFWAMLSFITRLPVPRRWSQGLDFEHYSRGIITFPLIGLLLGAISGL
VFMVLQAWCGAPLAALFSVLVLVLMTGGFHLDGLADTCDGVFSARSRDRM
LEIMRDSRLGTHGGLALIFVVLAKILVLSELALRGESILASLAAACAVSR
GTAALLMYRHRYAREEGLGNVFIGKIDGRQTCVTLGLAAIFAAVLLPGMH
GVAAMVVTMVAIFILGQLLKRTLGGQTGDTLGAAIELGELVFLLALL
>b1991 cobT, nicotinate-nucleotide dimethylbenzimidazole-P phophoribosyl transferase
MQILADLLNTIPAIDSTAMSRAQRHIDGLLKPVGSLGKLEVLAIQLAGMP
GLNGIPHVGKKAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVC
VLAEQAGANVHVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRRQAE
KLLLDVICYTQELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVV
GIGANLPTDKLANKIDVVRRAITLNQPNPQDGVDVLAKVGGFDLVGIAGV
MLGAASCGLPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIA
LSHLGLEPYLNMEMRLGEGSGAALAMPIIEAACAIYNNMGELAASNIVLP
GNTTSDLNS
>b1993 cobU, cobinamide kinase/cobinamide phosphate guanylyltransferase
MMILVTGGARSGKSRHAEALIGDSSQVLYIATSQILDDEMAARIEHHRQG
RPEHWRTVERWQHLDELIHADINPNEVVLLECVTTMVTNLLFDYGGDKDP
DEWDYQAMEQAINAEIQSLIAACQRCPAKVVLVTNEVGMGIVPESRLARH
FRDIAGRVNQQLAAAANEVWLVVSGIGVKIK
>b2752 cysD, ATP:sulfurylase (ATP:sulfate adenylyltransferase), subunit 2
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKA
FYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGI
NPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYS
FRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWL
ENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLG
CWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQG
YF
>b3368 cysG, uroporphyrinogen III methylase; sirohaeme biosynthesis
MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFT
AWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFC
NVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLH
LGQVAKYAGQLRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAI
TETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADVVVYDRL
VSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLK
GGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYA
QSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEHGMP
GEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDK
LNWFSNH
>b2762 cysH, 3'-phosphoadenosine 5'-phosphosulfate reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVL
SSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLN
LKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQ
TWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLK
YHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>b3639 dfp, flavoprotein affecting synthesis of DNA and pantothenate metabolism
MKARQQKYCDKIANFWCHPTGKIIMSLAGKKIVLGVSGGIAAYKTPELVR
RLRDRGADVRVAMTEAAKAFITPLSLQAVSGYPVSDSLLDPAAEAAMGHI
ELGKWADLVILAPATADLIARVAAGMANDLVSTICLATPAPVAVLPAMNQ
QMYRAAATQHNLEVLASRGLLIWGPDSGSQACGDIGPGRMLDPLTIVDMA
VAHFSPVNDLKHLNIMITAGPTREPLDPVRYISNHSSGKMGFAIAAAAAR
RGANVTLVSGPVSLPTPPFVKRVDVMTALEMEAAVNASVQQQNIFIGCAA
VADYRAATVAPEKIKKQATQGDELTIKMVKNPDIVAGVAALKDHRPYVVG
FAAETNNVEEYARQKRIRKNLDLICANDVSQPTQGFNSDNNALHLFWQDG
DKVLPLERKELLGQLLLDEIVTRYDEKNRR
>b0420 dxs, 1-deoxyxylulose-5-phosphate synthase; flavoprotein
MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVSRSSGHF
ASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQ
KGGLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVI
GDGAITAGMAFEAMNHAGDIRPDMLVILNDNEMSISENVGALNNHLAQLL
SGKLYSSLREGGKKVFSGVPPIKELLKRTEEHIKGMVVPGTLFEELGFNY
IGPVDGHDVLGLITTLKNMRDLKGPQFLHIMTKKGRGYEPAEKDPITFHA
VPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAAKDNKLMAITPAMREGS
GMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIYSTFLQRAY
DQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMT
PSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVK
RRGEKLAILNFGTLMPEAAKVAESLNATLVDMRFVKPLDEALILEMAASH
EALVTVEENAIMGGAGSGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEM
RAELGLDAAGMEAKIKAWLA
>b0593 entC, isochorismate hydroxymutase 2, enterochelin biosynthesis
MDTSLAEEVQQTMATLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPD
SPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQ
EKQASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVL
SRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLL
RKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMK
EVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHP
TPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAK
LRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH
>b4287 fecE, ATP-binding component of citrate-dependent iron(III) transport protein
MTLRTENLTVSYGTDKVLNDVSLSLPTGKITALIGPNGCGKSTLLNCFSR
LLMPQSGTVFLGDNPINMLSSRQLARRLSLLPQHHLTPEGITVQELVSYG
RNPWLSLWGRLSAEDNARVNVAMNQTRINHLAVRRLTELSGGQRQRAFLA
MVLAQNTPVVLLDEPTTYLDINHQVDLMRLMGELRTQGKTVVAVLHDLNQ
ASRYCDQLVVMANGHVMAQGTPEEVMTPGLLRTVFSVEAEIHPEPVSGRP
MCLMR
>b0588 fepC, ATP-binding component of ferric enterobactin transport
MTESVARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLL
RTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNATTPGDITVQE
LVARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQ
RAWIAMVLAQETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAV
LHDLNQACRYASHLIALREGKIVAQGAPKEIVTAELIERIYGLRCMIIDD
PVAGTPLVVPLGRTAPSTANS
>b0151 fhuC, ATP-binding component of hydroxymate-dependent iron transport
MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGK
STLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGM
TVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSG
GERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLT
VIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIYGIPMG
ILPHPAGAAPVSFVY
>b0048 folA, dihydrofolate reductase type I; trimethoprim resistance
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESI
GRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVY
EQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHS
YCFEILERR
>b2315 folC, dihydrofolate:folylpolyglutamate synthetase; dihydrofolate synthetase
MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSLVAARLGVLKPAPF
VFTVAGTNGKGTTCRTLESILMAAGYKVGVYSSPHLVRYTERVRVQGQEL
PESAHTASFAEIESARGDISLTYFEYGTLSALWLFKQAQLDVVILEVGLG
GRLDATNIVDADVAVVTSIALDHTDWLGPDRESIGREKAGIFRSEKPAIV
GEPEMPSTIADVAQEKGALLQRRGVEWNYSVTDHDWAFSDAHGTLENLPL
PLVPQPNAATALAALRASGLEVSENAIRDGIASAILPGRFQIVSESPRVI
FDVAHNPHAAEYLTGRMKALPKNGRVLAVIGMLHDKDIAGTLAWLKSVVD
DWYCAPLEGPRGATAEQLLEHLGNGKSFDSVAQAWDAAMADAKAEDTVLV
CGSFHTVAHVMEVIDARRSGGK
>b0529 folD, 5,10-methylene-tetrahydrofolate dehydrogenase; 5,10-methylene-tetrahydrofolate cyclohydrolase
MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIY
VASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLP
LPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLL
ERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHV
ENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAA
KRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQDE
>b2153 folE, GTP cyclohydrolase I
MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHMTEIMQL
LNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMV
TVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQ
VQERLTQQILIALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSL
GGLFKSSQNTRHEFLRAVRHHN
>b0142 folK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokin ase
MTVAYIAIGSNLASPLEQVNAALKALGDIPESHILTVSSFYRTPPLGPQD
QPDYLNAAVALETSLAPEELLNHTQRIELQQGRVRKAERWGPRTLDLDIM
LFGNEVINTERLTVPHYDMKNRGFMLWPLFEIAPELVFPDGEMLRQILHT
RAFDKLNKW
>b3177 folP, 7,8-dihydropteroate synthase
MLRGFFLSIHTRDNIMKLFAQGTSLDLSHPHVMGILNVTPDSFSDGGTHN
SLIDAVKHANLMINAGATIIDVGGESTRPGAAEVSVEEELQRVIPVVEAI
AQRFEVWISVDTSKPEVIRESAKVGAHIINDIRSLSEPGALEAAAETGLP
VCLMHMQGNPKTMQEAPKYDDVFAEVNRYFIEQIARCEQAGIAKEKLLLD
PGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGMSRKSMIGQLLNVGPSER
LSGSLACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAKENKRYE
>b2303 folX, D-erythro-7,8-dihydroneopterin tri P epimerase
MAQPAAIIRIKNLRLRTFIGIKEEEINNRQDIVINVTIHYPADKARTSED
INDALNYRTVTKNIIQHVENNRFSLLEKLTQDVLDIAREHHWVTYAEVEI
DKLHALRYADSVSMTLSWQR
>b3844 fre, ferrisiderophore reductase; flavin reductase (NADPH:flavin oxidoreductase)
MTTLSCKVTSVEAITDTVYRVRIVPDAAFSFRAGQYLMVVMDERDKRPFS
MASTPDEKGFIELHIGASEINLYAKAVMDRILKDHQIVVDIPHGEAWLRD
DEERPMILIAGGTGFSYARSILLTALARNPNRDITIYWGGREEQHLYDLC
ELEALSLKHPGLQVVPVVEQPEAGWRGRTGTVLTAVLQDHGTLAEHDIYI
AGRFEMAKIARDLFCSERNAREDRLFGDAFAFI
>b2688 gshA, gamma-glutamate-cysteine ligase
MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGS
ALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMW
PLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVH
YNFSLPMAFWQAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGA
SPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLGYTNKSQSNLG
ITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELY
APIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFL
DLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQF
PLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSAR
ILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQ
EMEAADTEPFAVWLEKHA
>b2947 gshB, glutathione synthetase
MIKLGIVMDPIANINIKKDSSFAMLLEAQRRGYELHYMEMGDLYLINGEA
RAHTRTLNVKQNYEEWFSFVGEQDLPLADLDVILMRKDPPFDTEFIYATY
ILERAEEKGTLIVNKPQSLRDCNEKLFTAWFSDLTPETLVTRNKAQLKAF
WEKHSDIILKPLDGMGGASIFRVKEGDPNLGVIAETLTEHGTRYCMAQNY
LPAIKDGDKRVLVVDGEPVPYCLARIPQGGETRGNLAAGGRGEPRPLTES
DWKIARQIGPTLKEKGLIFVGLDIIGDRLTEINVTSPTCIREIEAEFPVS
ITGMLMDAIEARLQQQ
>b1210 hemA, glutamyl-tRNA reductase
MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLAQPMVQGGVVLSTC
NRTELYLSVEEQDNLQEALIRWLCDYHNLNEEDLRKSLYWHQDNDAVSHL
MRVASGLDSLVLGEPQILGQVKKAFADSQKGHMKASELERMFQKSFSVAK
RVRTETDIGASAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARH
LREHKVQKMIIANRTRERAQILADEVGAEVIALSDIDERLREADIIISST
ASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSV
DDLQSIISHNLAQRKAAAVEAETIVAQETSEFMAWLRAQSASETIREYRS
QAEQVRDELTAKALAALEQGGDAQAIMQDLAWKLTNRLIHAPTKSLQQAA
RDGDNERLNILRDSLGLE
>b0369 hemB, 5-aminolevulinate dehydratase = porphobilinogen synthase
MPLDSTNIRQTMTDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEE
EIDDYKAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETG
SDAWREDGLVARMSRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVD
NDATLENLGKQAVVAAAAGADFIAPSAAMDGQVQAIRQALDAAGFKDTAI
MSYSTKFASSFYGPFREAAGSALKGDRKSYQMNPMNRREAIRESLLDEAQ
GADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEYAMIKFAALAGAID
EEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR
>b3805 hemC, porphobilinogen deaminase = hydroxymethylbilane synthase
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILD
TPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICE
REDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRG
NVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGA
VGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYA
ELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>b3804 hemD, uroporphyrinogen III synthase
MSILVTRPSPAGEELVSRLRTLGQVAWHFPLIEFSPGQQLPQLADQLAAL
GESDLLFALSQHAVAFAQSQLHQQDRKWPRLPDYFAIGRTTALALHTVSG
QKILYPQDREISEVLLQLPELQNIAGKRALILRGNGGRELIGDTLTARGA
EVTFCECYQRCAIHYDGAEEAMRWQAREVTMVVVTSGEMLQQLWSLIPQW
YREHWLLHCRLLVVSERLAKLARELGWQDIKVADNADNDALLRALQ
>b3997 hemE, uroporphyrinogen decarboxylase
MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAGDFMSLC
KNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFT
SPVTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWT
LATYMVEGGSSKAFTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAG
AQAVMIFDTWGGVLTGRDYQQFSLYYMHKIVDGLLRENDGRRVPVTLFTK
GGGQWLEAMAETGCDALGLDWTTDIADARRRVGNKVALQGNMDPSMLYAP
PARIEEEVATILAGFGHGEGHVFNLGHGIHQDVPPEHAGVFVEAVHRLSE
QYHR
>b2436 hemF, coproporphyrinogen III oxidase
MKPDAHQVKQFLLNLQDTICQQLTAVDGAEFVEDSWQREAGGGGRSRVLR
NGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNP
YVPTSHANVRFFIAEKPGADPVWWFGGGFDLTPFYGFEEDAIHWHRTARD
LCLPFGEDVYPRYKKWCDEYFYLKHRNEQRGIGGLFFDDLNTPDFDRCFA
FMQAVGKGYTDAYLPIVERRKAMAYGERERNFQLYRRGRYVEFNLVWDRG
TLFGLQTGGRTESILMSMPPLVRWEYDYQPKDGSPEAALSEFIKVRDWV
>b3850 hemG, protoporphyrin oxidase
MKTLILFSTRDGQTREIASYLASELKELGIQADVANVHRIEEPQWENYDR
VVIGASIRYGHYHSAFQEFVKKHATRLNSMPSAFYSVNLVARKPEKRTPQ
TNSYARKFLMNSQWRPDRCAVIAGALRYPRYRWYDRFMIKLIMKMSGGET
DTRKEVVYTDWEQVANFAREIAHLTDKPTLK
>b0475 hemH, ferrochelatase: final enzyme of heme biosynthesis
MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLLWWPLLR
GVILPLRSPRVAKLYASVWMEGGSPLMVYSRQQQQALAQRLPEMPVALGM
SYGSPSLESAVDELLAEHVDHIVVLPLYPQFSCSTVGAVWDELARILARK
RSIPGISFIRDYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRY
ADEGDDYPQRCRTTTRELASALGMAPEKVMMTFQSRFGREPWLMPYTDET
LKMLGEKGVGHIQVMCPGFAADCLETLEEIAEQNREVFLGAGGKKYEYIP
ALNATPEHIEMMANLVAAYR
>b0154 hemL, glutamate-1-semialdehyde aminotransferase (aminomutase)
MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGK
AYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVT
ELVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLL
VKAGSGALTLGQPNSPGVPADFAKYTLTCTYNDLASVRAAFEQYPQEIAC
IIVEPVAGNMNCVPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGA
QDYYGVVPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSG
NPIAMAAGFACLNEVAQPGVHETLDELTTRLAEGLLEAAEEAGIPLVVNH
VGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVYLAPSAFEA
GFMSVAHSMEDINNTIDAARRVFAKL
>b3867 hemN, O2-independent coproporphyrinogen III oxidase
MSMSVQQIDWDLALIQKYNYSGPRYTSYPTALEFSEDFGEQAFLQAVARY
PERPLSLYVHIPFCHKLCYFCGCNKIVTRQQHKADQYLDALEQEIVHRAP
LFAGRHVSQLHWGGGTPTYLNKAQISRLMKLLRENFQFNADAEISIEVDP
REIELDVLDHLRAEGFNRLSMGVQDFNKEVQRLVNREQDEEFIFALLNHA
REIGFTSTNIDLIYGLPKQTPESFAFTLKRVAELNPDRLSVFNYAHLPTI
FAAQRKIKDADLPSPQQKLDILQETIAFLTQSGYQFIGMDHFARPDDELA
VAQREGVLHRNFQGYTTQGDTDLLGMGVSAISMIGDCYAQNQKELKQYYQ
QVDEQGNALWRGIALTRDDCIRRDVIKSLICNFRLDYAPIEKQWDLHFAD
YFAEDLKLLAPLAKDGLVDVDEKGIQVTAKGRLLIRNICMCFDTYLRQKA
RMQQFSRVI
>b3803 hemX, uroporphyrinogen III methylase
MTEQEKTSAVVEETREAVDTTSQPVATEKKSKNNTALILSAVAIAIALAA
GIGLYGWGKQQAVNQTATSDALANQLTALQKAQESQKAELEGIIKQQAAQ
LKQANRQQETLAKQLDEVQQKVATISGSDAKTWLLAQADFLVKLAGRKLW
SDQDVTTAAALLKSADASLADMNDPSLITVRRAITDDIASLSAVSQVDYD
GIILKLNQLSNQVDNLRLADNDSDGSPMDSDGEELSSSISEWRINLQKSW
QNFMDNFITIRRRDDTAVPLLAPNQDIYLRENIRSRLLVAAQAVPRHQEE
TYRQALENVSTWVRAYYDTDDATTKAFLDEVDQLSQQNISMDLPETLQSQ
AMLEKLMQTRVRNLLAQPAAGTTEAKPAPAPQADTPAAAPQGE
>b3802 hemY, a late step of protoheme IX synthesis
MLKVLLLFVLLIAGIVVGPMIAGHQGYVLIQTDNYNIETSVTGLAIILIL
AMVVLFAIEWLLRRIFRTGAHTRGWFVGRKRRRARKQTEQALLKLAEGDY
QQVEKLMAKNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERAAELAGN
DTIPVEITRVRLQLARNENHAARHGVDKLLEVTPRHPEVLRLAEQAYIRT
GAWSSLLDIIPSMAKAHVGDEEHRAMLEQQAWIGLMDQARADNGSEGLRN
WWKNQSRKTRHQVALQVAMAEHLIECDDHDTAQQIIIDGLKRQYDDRLLL
PIPRLKTNNPEQLEKVLRQQIKNVGDRPLLWSTLGQSLMKHGEWQEASLA
FRAALKQRPDAYDYAWLADALDRLHKPEEAAAMRRDGLMLTLQNNPPQ
>b3671 ilvB, acetolactate synthase I,valine-sensitive, large subunit
MASSGTTSTRKRFTGAEFIVHFLEQQGIKIVTGIPGGSILPVYDALSQST
QIRHILARHEQGAGFIAQGMARTDGKPAVCMACSGPGATNLVTAIADARL
DSIPLICITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVRHIEELPQV
MSDAFRIAQSGRPGPVWIDIPKDVQTAVFEIETQPAMAEKAAAPAFSEES
IRDAAAMINAAKRPVLYLGGGVINAPARVRELAEKAQLPTTMTLMALGML
PKAHPLSLGMLGMHGVRSTNYILQEADLLIVLGARFDDRAIGKTEQFCPN
AKIIHVDIDRAELGKIKQPHVAIQADVDDVLAQLIPLVEAQPRAEWHQLV
ADLQREFPCPIPKACDPLSHYGLINAVAACVDDNAIITTDVGQHQMWTAQ
AYPLNRPRQWLTSGGLGTMGFGLPAAIGAALANPDRKVLCFSGDGSLMMN
IQEMATASENQLDVKIILMNNEALGLVHQQQSLFYEQGVFAATYPGKINF
MQIAAGFGLETCDLNNEADPQASLQEIINRPGPALIHVRIDAEEKVYPMV
PPGAANTEMVGE
>b3774 ilvC, ketol-acid reductoisomerase
MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGL
NQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQAD
LVINLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVV
MVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGG
HRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYA
EKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLF
QKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIG
EQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANT
IARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPE
GAVDNGQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG
>b3770 ilvE, branched-chain amino-acid aminotransferase
MTTKKADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYDSHKGPV
VFRHREHMQRLHDSAKIYRFPVSQSIDELMEACRDVIRKNNLTSAYIRPL
IFVGDVGMGVNPPAGYSTDVIIAAFPWGAYLGAEALEQGIDAMVSSWNRA
APNTIPTAAKAGGNYLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENL
FEVKDGVLFTPPFTSSALPGITRDAIIKLAKELGIEVREQVLSRESLYLA
DEVFMSGTAAEITPVRSVDGIQVGEGRCGPVTKRIQQAFFGLFTGETEDK
WGWLDQVNQ
>b0077 ilvI, acetolactate synthase III, valine sensitive, large subunit
MFMSLAANCLSKIGRLMCFTHFFRQTVRQAMEMLSGAEMVVRSLIDQGVK
QVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQAAVHMADGLARATGEVGV
VLVTSGPGATNAITGIATAYMDSIPLVVLSGQVATSLIGYDAFQECDMVG
ISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVDLPKDILNPAN
KLPYVWPESVSMRSYNPTTTGHKGQIKRALQTLVAAKKPVVYVGGGAITA
GCHQQLKETVEALNLPVVCSLMGLGAFPATHRQALGMLGMHGTYEANMTM
HNADVIFAVGVRFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVTADIPI
VGDARQVLEQMLELLSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSE
KIKPQAVIETLWRLTKGDAYVTSDVGQHQMFAALYYPFDKPRRWINSGGL
GTMGFGLPAALGVKMALPEETVVCVTGDGSIQMNIQELSTALQYELPVLV
VNLNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLAEAYGHVGIQISH
PHELESKLSEALEQVRNNRLVFVDVTVDGSEHVYPMQIRGGGMDEMWLSK
TERT
>b0421 ispA, geranyltranstransferase (farnesyl-diphosphate synthase)
MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGGKRLRPF
LVYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPT
CHVKFGEANAILAGDALQTLAFSILSDADMPEVSDRDRISMISELASASG
IAGMCGGQALDLDAEGKHVPLDALERIHRHKTGALIRAAVRLGALSAGDK
GRRALPVLDKYAESIGLAFQVQDDILDVVGDTATLGKRQGADQQLGKSTY
PALLGLEQARKKARDLIDDARQSLKQLAEQSLDTSALEALADYIIQRNK
>b3187 ispB, octaprenyl-diphosphate synthase
MNLEKINELTAQDMAGVNAAILEQLNSDVQLINQLGYYIVSGGGKRIRPM
IAVLAARAVGYEGNAHVTIAALIEFIHTATLLHDDVVDESDMRRGKATAN
AAFGNAASVLVGDFIYTRAFQMMTSLGSLKVLEVMSEAVNVIAEGEVLQL
MNVNDPDITEENYMRVIYSKTARLFEAAAQCSGILAGCTPEEEKGLQDYG
RYLGTAFQLIDDLLDYNADGEQLGKNVGDDLNEGKPTLPLLHAMHHGTPE
QAQMIRTAIEQGNGRHLLEPVLEAMNACGSLEWTRQRAEEEADKAIAALQ
VLPDTPWREALIGLAHIAVQRDR
>b3617 kbl, 2-amino-3-ketobutyrate CoA ligase (glycine acetyltransferase)
MRGEFYQQLTNDLETARAEGLFKEERIITSAQQADITVADGSHVINFCAN
NYLGLANHPDLIAAAKAGMDSHGFGMASVRFICGTQDSHKELEQKLAAFL
GMEDAILYSSCFDANGGLFETLLGAEDAIISDALNHASIIDGVRLCKAKR
YRYANNDMQELEARLKEAREAGARHVLIATDGVFSMDGVIANLKGVCDLA
DKYDALVMVDDSHAVGFVGENGRGSHEYCDVMGRVDIITGTLGKALGGAS
GGYTAARKEVVEWLRQRSRPYLFSNSLAPAIVAASIKVLEMVEAGSELRD
RLWANARQFREQMSAAGFTLAGADHAIIPVMLGDAVVAQKFARELQKEGI
YVTGFFYPVVPKGQARIRTQMSAAHTPEQITRAVEAFTRIGKQLGVIA
>b1380 ldhA, fermentative D-lactate dehydrogenase, NAD-dependent
MKLAVYSTKQYDKKYLQQVNESFGFELEFFDFLLTEKTAKTANGCEAVCI
FVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLKVVRVPAY
DPEAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTGFTMYGKTAGVI
GTGKIGVAMLRILKGFGMRLLAFDPYPSAAALELGVEYVDLPTLFSESDV
ISLHCPLTPENYHLLNEAAFEQMKNGVMIVNTSRGALIDSQAAIEALKNQ
KIGSLGMDVYENERDLFFEDKSNDVIQDDVFRRLSACHNVLFTGHQAFLT
AEALTSISQTTLQNLSNLEKGETCPNELV
>b0628 lipA, lipoate synthesis, sulfur insertion?
MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIKLPADST
RIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPF
CDVAHGRPVAPDANEPVKLAQTIADMALRYVVITSVDRDDLRDGGAQHFA
DCITAIREKSPQIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPR
IYRQVRPGADYNWSLKLLERFKEAHPEIPTKSGLMVGLGETNEEIIEVMR
DLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPDEFDEMKAEALAMGFTHAA
CGPFVRSSYHADLQAKGMEVK
>b0630 lipB, protein of lipoate biosynthesis
MHEFTDTRDDSTLDEIWLVEHYPVFTQGQAGKAEHILMPGDIPVIQSDRG
GQVTYHGPGQQVMYVLLNLKRRKLGVRELVTLLEQTVVNTLAELGIEAHP
RADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDLSPFLRINPCGYA
GMEMAKISQWKPEATTNNIAPRLLENILALLNNPDFEYITA
>b4386 lplA, lipoate-protein ligase A
MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQ
NPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTI
STSIVLNALNALGVSAEASGRNDLVVKTVEGDRKVSGSAYRETKDRGFHH
GTLLLNADLSRLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQV
CEAITEAFFAHYGERVEAEIISPNKTPDLPNFAETFARQSSWEWNFGQAP
AFSHLLDERFTWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQG
CLYRADMLQQECEALLVDFPEQEKELRELSAWMAGAVR
>b3930 menA, 1,4-dihydroxy-2-naphthoate-->dimethylmenaquinone
MTEQQISRTQAWLESLRPKTLPLAFAAIIVGTALAWWQGHFDPLVALLAL
ITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGVITQQEMKRALI
ITVVLICLSGLALVAVACHTLADFVGFLILGGLSIIAAITYTVGNRPYGY
IGLGDISVLVFFGWLSVMGSWYLQAHTLIPALILPATACGLLATAVLNIN
NLRDINSDRENGKNTLVVRLGEVNARRYHACLLMGSLVCLALFNLFSLHS
LWGWLFLLAAPLLVKQARYVMREMDPVAMRPMLERTVKGALLTNLLFVLG
IFLSQWAA
>b2262 menB, dihydroxynaphtoic acid synthetase
MIYPDEAMLYAPVEWHDCSEGFEDIRYEKSTDGIAKITINRPQVRNAFRP
LTVKEMIQALADARYDDNIGVIILTGAGDKAFCSGGDQKVRGDYGGYKDD
SGVHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAADNA
IFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGL
VNTVVPLADLEKETVRWCREMLQNSPMALRCLKAALNADCDGQAGLQELA
GNATMLFYMTEEGQEGRNAFNQKRQPDFSKFKRNP
>b2261 menC, o-succinylbenzoyl-CoA synthase; conversion of chorismate to 2-o-succinylbenzoyl-CoA
MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGEISPLPG
FSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELTDTLPQ
AANYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLL
EAIPDLHLRLDANRAWTPLKGQQFAKYVNPDYRDRIAFLEEPCKTRDDSR
AFARETGIAIAWDESLREPDFAFVAEEGVRAVVIKPTLTGSLEKVREQVQ
AAHALGLTAVISSSIESSLGLTQLARIAAWLTPDTIPGLDTLDLMQAQQV
RRWPGSTLPVVEVDALERLL
>b2264 menD, 2-oxoglutarate decarboxylase; SHCHC synthase
MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHH
THFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKL
ILLTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVS
TIDHALGTLHAGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWL
REAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALWAQTLGWPLIG
DVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQAS
CEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIP
RLAEQAMQAVIARRDAFGEAQLAHRICDYLPEQGQLFVGNSLVVRLIDAL
SQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLN
ALALLRQVSAPLVLIVVNNNGGQIFSLLPTPQSERERFYLMPQNVHFEHA
AAMFELKYHRPQNWQELETAFADAWRTPTTTVIEMVVNDTDGAQTLQQLL
AQVSHL
>b2265 menF, isochorismate hydroxymutase 2, menaquinone biosynthesis
MDQAQRFLRQHPEHADLRIWGLNAFDPSQGNLLLPRLEWRRCGGKATLRL
TLFSESSLQHDAIQAKEFIATLVSIKPLPGLHLTTTREQHWPDKTGWTQL
IELATKTIAEGELDKVVLARATDLHFASPVNAAAMMAASRRLNLNCYHFY
MAFDGENAFLGSSPERLWRRRDKALRTEALAGTVANNPDDKQAQQLGEWL
MADDKNQRENMLVVEDICQRLQADTQTLDVLPPQVLRLRKVQHLRRCIWT
SLNKADDVICLHQLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYL
SLQQSEFCVSLRSAKISGNVVRLYAGAGIVRGSDPEQEWQEIDNKAAGLR
TLLQME
>b3929 menG, menaquinone biosynthesis, unknown
MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFEDNGLLYD
LLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVD
DLEELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTG
IILSEDPLDIE
>b2942 metK, methionine adenosyltransferase 1 (AdoMet synthetase); methyl and propylamine donor, corepressor of met genes
MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGM
VLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQS
PDINQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQA
EVRKNGTLPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQ
EAVMEEIIKPILPAEWLTSATKFFINPTGRFVIGGPMGDCGLTGRKIIVD
TYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVS
YAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLHP
IYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK
>b0347 mhpA, 3-(3-hydroxyphenyl)propionate hydroxylase
MAIQHPDIQPAVNHSVQVAIAGAGPVGLMMANYLGQMGIDVLVVEKLDKL
IDYPRAIGIDDEALRTMQSVGLVDDVLPHTTPWHAMRFLTPKGRCFADIQ
PMTDEFGWPRRNAFIQPQVDAVMLEGVSRFPNVRCLFSRELEAFSQQDDE
VTLHLKTAEGQREIVKAQWLVACDGGASFVRRTLNVPFEGKTAPNQWIVV
DIANDPLSTPHIYLCCDPVRPYVSAALPHAVRRFEFMVMPGETEEQLREP
QNMRKLLSKVLPNPDNVELIRQRVYTHNARLAQRFRIDRVLLAGDAAHIM
PVWQGQGYNSGMRDAFNLAWKLALVIQGKARDALLDTYQQERRDHAKAMI
DLSVTAGNVLAPPKRWQGTLRDGVSWLLNYLPPVKRYFLEMRFKPMPQYY
GGALMREGEAKHSPVGKMFIQPKVTLENGDVTLLDNAIGANFAVIGWGCN
PLWGMSDEQIQQWRALGTRFIQVVPEVQIHTAQDNHDGVLRVGDTQGRLR
SWFAQHNASLVVMRPDRFVAATAIPQTLGKTLNKLASVMTLTRPDADVSV
EKVA
>b0781 moaA, molybdopterin biosynthesis, protein A
MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNKGFLTVD
EIRRVTRAFARLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTT
NGYRLERDVASWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDA
AFEAGFEKVKVNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGS
ELFRKHHISGQVLRDELLRRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIM
PYEKDFCATCNRLRVSSIGKLHLCLFGEGGVNLRDLLEDDTQQQALEARI
SAALREKKQTHFLHQNNTGITQNLSYIGG
>b0782 moaB, molybdopterin biosynthesis, protein B
MSQVSTEFIPTRIAILTVSNRRGEEDDTSGHYLRDSAQEAGHHVVDKAIV
KENRYAIRAQVSAWIASDDVQVVLITGGTGLTEGDQAPEALLPLFDREVE
GFGEVFRMLSFEEIGTSTLQSRAVAGVANKTLIFAMPGSTKACRTAWENI
IAPQLDARTRPCNFHPHLKK
>b0783 moaC, molybdopterin biosynthesis, protein C
MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHH
KGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIE
TLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGG
KSGDFKVEADD
>b0784 moaD, molybdopterin biosynthesis
MIKVLFFAQVRELVGTDATEVAADFPTVEALRQHMAAQSDRWALALEDGK
LLAAVNQTLVSFDHPLTDGDEVAFFPPVTGG
>b0785 moaE, molybdopterin converting factor, subunit 2
MAETKIVVGPQPFSVGEEYPWLAERDEDGAVVTFTGKVRNHNLGDSVNAL
TLEHYPGMTEKALAEIVDEARNRWPLGRVTVIHRIGELWPGDEIVFVGVT
SAHRSSAFEAGQFIMDYLKTRAPFWKREATPEGDRWVEARESDQQAAKRW
>b3857 mobA, molybdopterin---> molybdopterin-guanine dinucleotide, protein Ar
MNLMTTITGVVLAGGKARRMGGVDKGLLELNGKPLWQHVADALMTQLSHV
VVNANRHQEIYQASGLKVIEDSLADYPGPLAGMLSVMQQEAGEWFLFCPC
DTPYIPPDLAARLNHQRKDAPVVWVHDGERDHPTIALVNRAIEPLLLEYL
QAGERRVMVFMRLAGGHAVDFSDHKDAFVNVNTPEELARWQEKR
>b3856 mobB, molybdopterin-guanine dinucleotide biosynthesis protein B
MIPLLAFAAWSGTGKTTLLKKLIPALCARGIRPGLIKHTHHDMDVDKPGK
DSYELRKAGAAQTIVASQQRWALMTETPDEEELDLQFLASRMDTSKLDLI
LVEGFKHEEIAKIVLFRDGAGHRPEELVIDRHVIAVASDVPLNLDVALLD
INDVEGLADFVVEWMQKQNG
>b0827 moeA, molybdopterin biosynthesis
MEFTTGLMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDVVSPLDV
PGFDNSAMDGYAVRLADIASGQPLPVAGKSFAGQPYHGEWPAGTCIRIMT
GAPVPEGCEAVVMQEQTEQMDNGVRFTAEVRSGQNIRRRGEDISAGAVVF
PAGTRLTTAELPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQ
IYDTNRLAVHLMLEQLGCEVINLGIIRDDPHALRAAFIEADSQADVVISS
GGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGN
PVSATLTFYQLVQPLLAKLSGNTASGLPARQRVRTASRLKKTPGRLDFQR
GVLQRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGNVEVGEWVE
VEPFNALFGGL
>b0826 moeB, molybdopterin biosynthesis
MAELSDQEMLRYNRQIILRGFDFDGQEALKDSRVLIVGLGGLGCAASQYL
ASAGVGNLTLLDFDTVSLSNLQRQTLHSDATVGQPKVESARDALTRINPH
IAITPVNALLDDAELAALIAEHDLVLDCTDNVAVRNQLNAGCFAAKVPLV
SGAAIRMEGQITVFTYQDGEPCYRCLSRLFGENALTCVEAGVMAPLIGVI
GSLQAMEAIKMLAGYGKPASGKIVMYDAMTCQFREMKLMRNPGCEVCGQ
>b0009 mog, putative molybdochetalase in molybdopterine biosynthesis
MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDE
QAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFG
EQMRQISLHFVPTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKDAE
GNVVVHGIFASVPYCIQLLEGPYVETAPEVVAAFRPKSARRDVSE
>b0750 nadA, quinolinate synthetase, A protein
MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYT
DPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSP
EKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARA
DWVVTSSIAVELIDHLDSLGEKIIWAPDKHLGRYVQKQTGGDILCWQGAC
IVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVDMADAVGSTSQLIAAA
KTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWM
AMNGLQAIAEALEQEGSNHEVHVDERLRERALVPLNRMLDFAATLRG
>b2574 nadB, quinolinate synthetase, B protein
MNTLPEHSCDVLIIGSGAAGLSLALRLADQHQVIVLSKGPVTEGSTFYAQ
GGIAAVFDETDSIDSHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQ
GVLFDTHIQPNGEESYHLTREGGHSHRRILHAADATGREVETTLVSKALN
HPNIRVLERSNAVDLIVSDKIGLPGTRRVVGAWVWNRNKETVETCHAKAV
VLATGGASKVYQYTTNPDISSGDGIAMAWRAGCRVANLEFNQFHPTALYH
PQARNFLLTEALRGEGAYLKRPDGTRFMPDFDERGELAPRDIVARAIDHE
MKRLGADCMFLDISHKPADFIRQHFPMIYEKLLGLGIDLTQEPVPIVPAA
HYTCGGVMVDDHGRTDVEGLYAIGEVSYTGLHGANRMASNSLLECLVYGW
SAAEDITRRMPYAHDISTLPPWDESRVENPDERVVIQHNWHELRLFMWDY
VGIVRTTKRLERALRRITMLQQEIDEYYAHFRVSNNLLELRNLVQVAELI
VRCAMMRKESRGLHFTLDYPELLTHSGPSILSPGNHYINR
>b0109 nadC, quinolinate phosphoribosyltransferase
MPPRRYNPDTRRDELLERINLDIPGAVAQALREDLGGTVDANNDITAKLL
PENSRSHATVITRENGVFCGKRWVEEVFIQLAGDDVTIIWHVDDGDVINA
NQSLFELEGPSRVLLTGERTALNFVQTLSGVASKVRHYVELLEGTNTQLL
DTRKTLPGLRSALKYAVLCGGGANHRLGLSDAFLIKENHIIASGSVRQAV
EKASWLHPDAPVEVEVENLEELDEALKAGADIIMLDNFETEQMREAVKRT
NGKALLEVSGNVTDKTLREFAETGVDFISVGALTKHVQALDLSMRFR
>b0639 nadD, NAMN adenylyltransferase
MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPPHRPQPE
ANSVQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDV
PLAFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWL
EDHLTHNPEDLHLQPAGKIYLAETPWFNISATIIRERLQNGESCEDLLPE
PVLTYINQQGLYR
>b1740 nadE, NAD synthetase, prefers NH3 over glutamine
MTLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLVLGISGG
QDSTLAGKLCQMAINELRLETGNESLQFIAVRLPYGVQADEQDCQDAIAF
IQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIA
GMTSGVVVGTDHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALA
CPEHLYKKAPTADLEDDRPSLPDEVALGVTYDNIDDYLEGKNVPQQVART
IENWYLKTEHKRRPPITVFDDFWKK
>b4390 nadR, probable nadAB transcriptional regulator
MRYTEGDMSSFDYLKTAIKQQGCTLQQVADASGMTKGYLSQLLNAKIKSP
SAQKLEALHRFLGLEFPRQKKTIGVVFGKFYPLHTGHIYLIQRACSQVDE
LHIIMGFDDTRDRALFEDSAMSQQPTVPDRLRWLLQTFKYQKNIRIHAFN
EEGMEPYPHGWDVWSNGIKKFMAEKGIQPDLIYTSEEADAPQYMEHLGIE
TVLVDPKRTFMSISGAQIRENPFRYWEYIPTEVKPFFVRTVAILGGESSG
KSTLVNKLANIFNTTSAWEYGRDYVFSHLGGDEIALQYSDYDKIALGHAQ
YIDFAVKYANKVAFIDTDFVTTQAFCKKYEGREHPFVQALIDEYRFDLVI
LLENNTPWVADGLRSLGSSVDRKEFQNLLVEMLEENNIEFVRVEEEDYDS
RFLRCVELVREMMGEQR
>b1398 paaK, phenylacetate-CoA ligase
MITNTKLDPIETASVDELQALQTQRLKWTLKHAYENVPMYRRKFDAAGVH
PDDFRELSDLRKFPCTTKQDLRDNYPFDTFAVPMEQVVRIHASSGTTGKP
TVVGYTQNDIDNWANIVARSLRAAGGSPKDKIHVAYGYGLFTGGLGAHYG
AERLGATVIPMSGGQTEKQAQLIRDFQPDMIMVTPSYCLNLIEELERQLG
GDASGCSLRVGVFGAEPWTQAMRKEIERRLGITALDIYGLSEVMGPGVAM
ECLETTDGPTIWEDHFYPEIVNPHDGTPLADGEHGELLFTTLTKEALPVI
RYRTRDLTRLLPGTARTMRRMDRISGRSDDMLIIRGVNVFPSQLEEEIVK
FEHLSPHYQLEVNRRGHLDSLSVKVELKESSLTLTHEQRCQVCHQLRHRI
KSMVGISTDVMIVNCGSIPRSEGKACRVFDLRNIVGA
>b3360 pabA, p-aminobenzoate synthetase, component II
MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDALKPQKIVIS
PGPCTPDEAGISLDVIRHYAGRLPILGVCLGHQAMAQAFGGKVVRAAKVM
HGKTSPITHNGEGVFRGLANPLTVTRYHSLVVEPDSLPACFDVTAWSETR
EIMGIRHRQWDLEGVQFHPESILSEQGHQLLANFLHR
>b1812 pabB, p-aminobenzoate synthetase, component I
MKTLSPAVITLLWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYSRFDIVV
AEPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQVLDRADIRPTHNEDL
PFQGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRH
TVSLLSHNDVNARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQV
QEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAPFSAFLRLEQG
AILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAVKLANSAKDR
AENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHLVSTITAQLPE
QLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFC
GNMDTSITIRTLTAINGQIFCSAGGGIVADSQEEAEYQETFDKVNRILKQ
LEK
>b1096 pabC, 4-amino-4-deoxychorismate lyase
MFLINGHKQESLAVSDRATQFGDGCFTTARVIDGKVSLLSAHIQRLQDAC
QRLMISCDFWPQLEQEMKTLAAEQQNGVLKVVISRGSGGRGYSTLNSGPA
TRILSVTAYPAHYDRLRNEGITLALSPVRLGRNPHLAGIKHLNRLEQVLI
RSHLEQTNADEALVLDSEGWVTECCAANLFWRKGNVVYTPRLDQAGVNGI
MRQFCIRLLAQSSYQLVEVQASLEESLQADEMVICNALMPVMPVCACGDV
SFSSATLYEYLAPLCERPN
>b0134 panB, 3-methyl-2-oxobutanoate hydroxymethyltransferase
MKPTTISLLQKYKQEKKRFATITAYDYSFAKLFADEGLNVMLVGDSLGMT
VQGHDSTLPVTVADIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENA
ATVMRAGANMVKIEGGEWLVETVQMLTERAVPVCGHLGLTPQSVNIFGGY
KVQGRGDEAGDQLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVI
GIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAETGDIRAAVRQYMAE
VESGVYPGEEHSFH
>b0133 panC, pantothenate synthetase
MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEAKARADV
VVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYP
NGTETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGE
KDFQQLALIRKMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKI
APGLYKVLSSIADKLQAGERDLDEIITIAGQELNEKGFRADDIQIRDADT
LLEVSETSKRAVILVAAWLGDARLIDNKMVELA
>b0131 panD, aspartate 1-decarboxylase
MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVT
NGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEART
WRPNVAYFEGDNEMKRTAKAIPVQVA
>b3258 panF, sodium/pantothenate symporter
MTMQLEVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMGGIVL
AMTLTATYISASSFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKF
AILARRYNAVTLNDMLFARYQSRLLVWLASLSLLVAFVGAMTVQFIGGAR
LLETAAGIPYETGLLIFGISIALYTAFGGFRASVLNDTMQGLVMLIGTVV
LLIGVVHAAGGLSNAVQTLQTIDPQLVTPQGADDILSPAFMTSFWVLVCF
GVIGLPHTAVRCISYKDSKAVHRGIIIGTIVVAILMFGMHLAGALGRAVI
PDLTVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQLLQSSATII
KDLYLNIRPDQMQNETRLKRMSAVITLVLGALLLLAAWKPPEMIIWLNLL
AFGGLEAVFLWPLVLGLYWERANAKGALSAMIVGGVLYAVLATLNIQYLG
FHPIVPSLLLSLLAFLVGNRFGTSVPQATVLTTDK
>b0052 pdxA, pyridoxine biosynthesis
MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLTNRAAML
GLPLTLRPYSPNSPAQPQTAGTLTLLPVALRAPVTAGQLAVENGHYVVET
LARACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVV
MMLATEELRVALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAE
PRILVCGLNPHAGEGGHMGTEEIDTIIPVLNELRAQGMKLNGPLPADTLF
QPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTA
LELAGRGKADVGSFITALNLAIKMIVNTQ
>b2320 pdxB, erythronate-4-phosphate dehyrogenase
MKILVDENMPYARDLFSRLGEVTAVPGRPIPVAQLADADALMVRSVTKVN
ESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVF
SSLLMLAERDGFSLYDRTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRA
DRGDEGDFRSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPG
AILINACRGAVVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLKKVDI
GTSHIAGYTLEGKARGTTQVFEAYSKFIGHEQHVALDTLLPAPEFGRITL
HGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPGEFDKLRKNYLERREWS
SLYVICDDASAASLLCKLGFNAVHHPAR
>b1638 pdxH, pyridoxinephosphate oxidase
MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACEAKLADP
TAMVVATVDEHGQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQIENNPRVS
LLFPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGAWVSKQSSRI
SARGILESKFLELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHD
RFLYQRENDAWKIDRLAP
>b2564 pdxJ, pyridoxine biosynthesis
MAELLLGVNIDHIATLRNARGTAYPDPVQAAFIAEQAGADGITVHLREDR
RHITDRDVRILRQTLDTRMNLEMAVTEEMLAIAVETKPHFCCLVPEKRQE
VTTEGGLDVAGQRDKMRDACKRLADAGIQVSLFIDADEEQIKAAAEVGAP
FIEIHTGCYADAKTDAEQAQELARIAKAATFAASLGLKVNAGHGLTYHNV
KAIAAIPEMHELNIGHAIIGRAVMTGLKDAVAEMKRLMLEARG
>b2418 pdxK, pyridoxal/pyridoxine/pyridoxamine kinase
MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVP
TVLLSNTPHYDTFYGGAIPDEWFSGYLRALQERDALRQLRAVTTGYMGTA
SQIKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLL
PLAQGITPNIFELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVVTSASGN
EENQEMQVVVVTADSVNVISHSRVKTDLKGTGDLFCAQLISGLLKGKALT
DAVHRAGLRVLEVMRYTQQHESDELILPPLAEA
>b1636 pdxY, pyridoxal kinase 2 / pyridoxine kinase
MMKNILAIQSHVVYGHAGNSAAEFPMRRLGANVWPLNTVQFSNHTQYGKW
TGCVMPPSHLTEIVQGIAAIDKLHTCDAVLSGYLGSAEQGEHILGIVRQV
KAANPQAKYFCDPVMGHPEKGCIVAPGVAEFHVRHGLPASDIIAPNLVEL
EILCEHAVNNVEEAVLAARELIAQGPQIVLVKHLARAGYSRDRFEMLLVT
ADEAWHISRPLVDFGMRQPVGVGDVTSGLLLVKLLQGATLQEALEHVTAA
VYEIMVTTKAMQEYELQVVAAQDRIAKPEHYFSATKL
>b0931 pncB, nicotinate phosphoribosyltransferase
MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGDDLLGIY
ADAIREQVQAMQHLRLQDDEYQWLSALPFFKADYLNWLREFRFNPEQVTV
SNDNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTL
ESKLVDFSALTAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQESWFVG
TSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLANSQRAALAAWLEEYPD
QLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYEK
LGIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQLSFGIGTRLTCDIPQVK
PLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPHIKKAS
>b0751 pnuC, required for NMN transport
MDFFSVQNILVHIPIGAGGYDLSWIEAVGTIAGLLCIGLASLEKISNYFF
GLINVTLFGIIFFQIQLYASLLLQVFFFAANIYGWYAWSRQTSQNEAELK
IRWLPLPKALSWLAVCVVSIGLMTVFINPVFAFLTRVAVMIMQALGLQVV
MPELQPDAFPFWDSCMMVLSIVAMILMTRKYVENWLLWVIINVISVVIFA
LQGVYAMSLEYIILTFIALNGSRMWINSARERGSRALSH
>b0871 poxB, pyruvate oxidase
MKQTVAAYIAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEWMSTRHE
EVAAFAAGAEAQLSGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAA
HIPSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVL
NRGVSVVVLPGDVALKPAPEGATMHWYHAPQPVVTPEEEELRKLAQLLRY
SSNIALMCGSGCAGAHKELVEFAGKIKAPIVHALRGKEHVEYDNPYDVGM
TGLIGFSSGFHTMMNADTLVLLGTQFPYRAFYPTDAKIIQIDINPASIGA
HSKVDMALVGDIKSTLRALLPLVEEKADRKFLDKALEDYRDARKGLDDLA
KPSEKAIHPQYLAQQISHFAADDAIFTCDVGTPTVWAARYLKMNGKRRLL
GSFNHGSMANAMPQALGAQATEPERQVVAMCGDGGFSMLMGDFLSVVQMK
LPVKIVVFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGITGIR
VEKASEVDEALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYM
LRAIISGRGDEVIELAKTNWLR
>b1277 ribA, GTP cyclohydrolase II
MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHTPVLARV
HSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLN
KIRAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTN
NPKKVEILTEAGINIVERVPLIVGRNPNNEHYLDTKAEKMGHLLNK
>b3041 ribB, 3,4 dihydroxy-2-butanone-4-phosphate synthase
MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMIFPAETM
TVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIE
AAEGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTR
GGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALV
TIEDLVAYRQAHERKAS
>b1662 ribC, riboflavin synthase, alpha chain
MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAHNGCCLT
VTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMS
GHIMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVG
EVTPTRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLA
ARENAMNQPGTEA
>b0414 ribD, diaminohydroxyphosphoribosylaminopyrimidine deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase
MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQRAGEPH
AEVHALRMAGEKAKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVASM
QDPNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQ
LKLGASLDGRTAMASGESQWITSPQARRDVQLLRAQSHAILTSSATVLAD
DPALTVRWSELDEQTQALYPQQNLRQPIRIVIDSQNRVTPVHRIVQQPGE
TWFARTQEDSREWPETVRTLLIPEHKGHLDLVVLMMQLGKQQINSIWVEA
GPTLAGALLQAGLVDELIVYIAPKLLGSDARGLCTLPGLEKLADAPQFKF
KEIRHVGPDVCLHLVGA
>b0415 ribE, riboflavin synthase, beta chain
MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQVKDENIT
VVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNG
LAHVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINV
LKAIKA
>b0025 ribF, flavokinase and FAD synthetase
MKLIRGIHNLSQAPQEGCVLTIGNFDGVHRGHRALLQGLQEEGRKRNLPV
MVMLFEPQPLELFATDKAPARLTRLREKLRYLAECGVDYVLCVRFDRRFA
ALTAQNFISDLLVKHLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFD
ITSTQTFCEGGVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDE
LGRTIGFPTANVPLRRQVSPVKGVYAVEVLGLGEKPLPGVANIGTRPTVA
GIRQQLEVHLLDVAMDLYGRHIQVVLRKKIRNEQRFASLDELKAQIARDE
LTAREFFGLTKPA
>b0852 rimK, ribosomal protein S6 modification protein
MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPAASSIHY
KGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDK
LRSMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIG
VVLAETRQAAESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAA
IERRAKEGDFRSNLHRGGAASVASITPQEREIAIKAARTMALDVAGVDIL
RANRGPLVMEVNASPGLEGIEKTTGIDIAGKMIRWIERHATTEYCLKTGG
>b2913 serA, D-3-phosphoglycerate dehydrogenase
MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKES
IRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIP
VFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEAR
GKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDL
LNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALC
DALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEA
QENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPLHGGRRLMHIHENRPGV
LTALNKIFAEQGVNIAAQYLQTSAQMGYVVIDIEADEDVAEKALQAMKAI
PGTIRARLLY
>b0907 serC, 3-phosphoserine aminotransferase
MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGKEFIQVA
EEAEKDFRDLLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAG
YWAASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMREWQLSDNAAYMHYCP
NETIDGIAIDETPDFGADVVVAADFSSTILSRPIDVSRYGVIYAGAQKNI
GPAGLTIVIVREDLLGKANIACPSILDYSILNDNGSMFNTPPTFAWYLSG
LVFKWLKANGGVAEMDKINQQKAELLYGVIDNSDFYRNDVAKANRSRMNV
PFQLADSALDKLFLEESFAAGLHALKGHRVVGGMRASIYNAMPLEGVKAL
TDFMVEFERRHG
>b0068 tbpA, thiamin-binding periplasmic protein
MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAFEADCNC
ELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSG
VAADAVNVPGGWNNDTFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQN
WRVIYQDPRTSTPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEA
YGLFLKGESDLVLSYTTSPAYHILEEKKDNYAAANFSEGHYLQVEVAART
AASKQPELAQKFLQFMVSPAFQNAIPTGNWMYPVANVTLPAGFEKLTKPA
TTLEFTPAEVAAQRQAWISEWQRAVSR
>b3994 thiC, thiamin (pyrimidine moiety) biosynthesis protein
MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQ
LSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPW
IDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQL
HYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITA
EFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIE
EEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQAL
EKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTG
IVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGS
IQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEE
LEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKE
HLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWE
DQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDY
AATQTIEMGMADMSENFRARGGEIYLRKEEA
>b2103 thiD, phosphomethylpyrimidine kinase
MKRINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAQNTRGVQ
SVYRIEPDFVAAQLDSVFSDVRIDTTKIGMLAETDIVEAVAERLQRYQIQ
NVVLDTVMLAKSGDPLLSPSAVATLRSRLLPQVSLITPNLPEAAALLDAP
HARTEQEMLEQGRSLLAMGCGAVLMKGGHLDDEQSPDWLFTREGEQRFTA
PRIMTKNTHGTGCTLSAALAALRPRHTNWADTVQEAKSWLSSALAQADTL
EVGHGIGPVHHFHAWW
>b3993 thiE, thiamin-phosphate synthase (thiamine-phosphate pyrophosphorylase)
MYQPDFPPVPFRSGLYPVVDSVQWIERLLDAGVRTLQLRIKDRRDEEVEA
DVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLNAIRA
AGLRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLA
RHVERLADYPTVAIGGISLARAPAVIATGVGSIAVVSAITQAADWRLATA
QLLEIAGVGDE
>b3992 thiF, adenylyltransferase
MRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAALYLAGAGVGTLV
LADDDDVHLSNLQRQILFTTEDIDRPKSQVSQQRLTQLNPDIQLTALQQR
LTGEALKDAVARADVVLDCTDNMATRQEINAACVALNTPLITASAVGFGG
QLMVLTPPWEQGCYRCLWPDNQEPERNCRTAGVVGPVVGVMGTLQALEAI
KLLSGIETPAGELRLFDGKSSQWRSLALRRASGCPVCGGSNADPV
>b3991 thiG, thiamin (thiazole moiety) biosynthesis protein
MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKRVDLRQH
NDAILEPLIAAGVTLLPNTSGAKTAEEAIFAAHLAREALGTNWLKLEIHP
DARWLLPDPIETLKAAETLVQQGFVVLPYCGADPVLCKRLEEVGCAAVMP
LGAPIGSNQGLETRAMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADA
VLVNTAIAVADDPVNMAKAFRLAVEAGLLARQSGPGSRSYFAHATSPLTG
FLEASA
>b3990 thiH, thiamin (thiazole moiety) biosynthesis protein
MKTFSDRWRQLDWDDIRLRINGKTAADVERALNASQLTRDDMMALLSPAA
SGYLEQLAQRAQRLTRQRFGNTVSFYVPLYLSNLCANDCTYCGFSMSNRI
KRKTLDEADIARESAAIREMGFEHLLLVTGEHQAKVGMDYFRRHLPALRE
QFSSLQMEVQPLAETEYAELKQLGLDGVMVYQETYHEATYARHHLKGKKQ
DFFWRLETPDRLGRAGIDKIGLGALIGLSDNWRVDSYMVAEHLLWLQQHY
WQSRYSVSFPRLRPCTGGIEPASIMDERQLVQTICAFRLLAPEIELSLST
RESPWFRDRVIPLAINNVSAFSKTQPGGYADNHPELEQFSPHDDRRPEAV
AAALTAQGLQPVWKDWDSYLGRASQRL
>b0417 thiL, thiamin-monophosphate kinase
MACGEFSLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAISTDTLV
AGNHFLPDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPDVDEAWL
ESFSDSLFDLLNYYDMQLIGGDTTRGPLSMTLGIHGFVPMGRALTRSGAK
PGDWIYVTGTPGDSAAGLAILQNRLQVADAKDADYLIKRHLRPSPRILQG
QALRDLANSAIDLSDGLISDLGHIVKASDCGARIDLALLPFSDALSRHVE
PEQALRWALSGGEDYELCFTVPELNRGALDVALGHLGVPFTCIGQMTADI
EGLCFIRDGEPVTLDWKGYDHFATP
>b2104 thiM, hydoxyethylthiazole kinase
MQVDLLGSAQSAHALHLFHQHSPLVHCMTNDVVQTFTANTLLALGASPAM
VIETEEASQFAAIASALLINVGTLTQPRAQAMRAAVEQAKSSQTPWTLDP
VAVGALDYRRHFCHELLSFKPAAIRGNASEIMALAGIANGGRGVDTTDAA
ANAIPAAQTLARETGAIVVVTGEMDYVTDGHRIIGIHGGDPLMTKVVGTG
CALSAVVAACCALPGDTLENVASACHWMKQAGERAVARSEGPGSFVPHFL
DALWQLTQEVQA
>b4407 thiS, sulfur carrier protein
MQILFNDQAMQCAAGQTVHELLEQLDQRQAGAALAINQQIVPREQWAQHI
VQDGDQILLFQVIAGG
>b3553 tkrA, 2-ketoaldonate reductase
MERSMKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFAEA
EGLLGSNENVNAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTP
TVLTETVADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHK
TLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDT
LLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENAL
IAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYG
MAACAVDNLIDALQGKVEKNCVNPHVAD
>b1263 trpD, anthranilate synthase component II, glutamine amidotransferase and phosphoribosylanthranilate transferase
MADILLLDNIDSFTYNLADQLRSNGHNVVIYRNHIPAQTLIERLATMSNP
VLMLSPGPGVPSEAGCMPELLTRLRGKLPIIGICLGHQAIVEAYGGYVGQ
AGEILHGKASSIEHDGQAMFAGLTNPLPVARYHSLVGSNIPAGLTINAHF
NGMVMAVRHDADRVCGFQFHPESILTTQGARLLEQTLAWAQQKLEPANTL
QPILEKLYQAQTLSQQESHQLFSAVVRGELKPEQLAAALVSMKIRGEHPN
EIAGAATALLENAAPFPRPDYLFADIVGTGGDGSNSINISTASAFVAAAC
GLKVAKHGNRSVSSKSGSSDLLAAFGINLDMNADKSRQALDELGVCFLFA
PKYHTGFRHAMPVRQQLKTRTLFNVLGPLINPAHPPLALIGVYSPELVLP
IAETLRVLGYQRAAVVHSGGMDEVSLHAPTIVAELHDGEIKSYQLTAEDF
GLTPYHQEQLAGGTPEENRDILTRLLQGKGDAAHEAAVAANVAMLMRLHG
HEDLQANAQTVLEVLRSGSAYDRVTALAARG
>b1264 trpE, anthranilate synthase component I
MQTQKPTLELLTCEGAYRDNPTALFHQLCGDRPATLLLESADIDSKDDLK
SLLLVDSALRITALGDTVTIQALSGNGEALLALLDNALPAGVESEQSPNC
RVLRFPPVSPLLDEDARLCSLSVFDAFRLLQNLLNVPKEEREAMFFGGLF
SYDLVAGFEDLPQLSAENNCPDFCFYLAETLMVIDHQKKSTRIQASLFAP
NEEEKQRLTARLNELRQQLTEAAPPLPVVSVPHMRCECNQSDEEFGGVVR
LLQKAIRAGEIFQVVPSRRFSLPCPSPLAAYYVLKKSNPSPYMFFMQDND
FTLFGASPESSLKYDATSRQIEIYPIAGTRPRGRRADGSLDRDLDSRIEL
EMRTDHKELSEHLMLVDLARNDLARICTPGSRYVADLTKVDRYSYVMHLV
SRVVGELRHDLDALHAYRACMNMGTLSGAPKVRAMQLIAEAEGRRRGSYG
GAVGYFTAHGDLDTCIVIRSALVENGIATVQAGAGVVLDSVPQSEADETR
NKARAVLRAIATAHHAQETF
>b4040 ubiA, 4-hydroxybenzoate-octaprenyltransferase
MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILA
VFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALF
VVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAF
GWSIPMAFAAVSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGI
KSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAGALF
VYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
>b4039 ubiC, chorismate lyase
MRLLRFCCVLDHLICFTSPVNTFLRYNAFTLCNGEFGMSHPALTQLRALR
YCKEIPALDPQLLDWLLLEDSMTKRFEQQGKTVSVTMIREGFVEQNEIPE
ELPLLPKESRYWLREILLCADGEPWLAGRTVVPVSTLSGPELALQKLGKT
PLGRYLFTSSTLTRDFIEIGRDAGLWGRRSRLRLSGKPLLLTELFLPASP
LY
>b3843 ubiD, 3-octaprenyl-4-hydroxybenzoate decarboxylase
MDAMKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLRAGGPAL
LFENPKGYSMPVLCNLFGTPKRVAMGMGQEDVSALREVGKLLAFLKEPEP
PKGFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLNRIPIMTC
WPEDAAPLITWGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGA
LDYQEWCAAHPGERFPVSVALGADPATILGAVTPVPDTLSEYAFAGLLRG
TKTEVVKCISNDLEVPASAEIVLEGYIEQGETAPEGPYGDHTGYYNEVDS
FPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGVALNEVFVPILQKQFPE
IVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQFMYTKFVIV
CDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSK
MGLDATNKWPGETQREWGRPIKKDPDVVAHIDAIWDELAIFNNGKSA
>b3833 ubiE, 2-octaprenyl-6-methoxy-1,4-benzoquinone-->2-octa prenyl-3-methyl-6-methoxy-1,4-benzoquinone
MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMSFGIHRL
WKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESM
LKMGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKD
KALRSMYRVLKPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVAN
DADSYRYLAESIRMHPDQDTLKAMMQDAGFESVDYYNLTAGVVALHRGYK
F
>b0662 ubiF, 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase
MTNQPTEIAIVGGGMVGGALALGLAQHGFAVTVIEHAEPAPFVADSQPDV
RISAISAASVSLLKGLGVWDAVQAMRCHPYRRLETWEWETAHVVFDAAEL
KLPLLGYMVENTVLQQALWQALEAHPKVTLRVPGSLIALHRHDDLQELEL
KGGEVIRAKLVIGADGANSQVRQMAGIGVHAWQYAQSCMLISVQCENDPG
DSTWQQFTPDGPRAFLPLFDNWASLVWYDSPARIRQLQNMNMAQLQAEIA
KHFPSRLGYVTPLAAGAFPLTRRHALQYVQPGLALVGDAAHTIHPLAGQG
VNLGYRDVDALIDVLVNARSYGEAWASYPVLKRYQMRRMADNFIMQSGMD
LFYAGFSNNLPPLRFMRNLGLMAAERAGVLKRQALKYALGL
>b2232 ubiG, 3-demethylubiquinone-9 3-methyltransferase and 2-octaprenyl-6-hydroxy phenol methylase
MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAE
RAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALE
SGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVK
PGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGW
VDQTSLKERHITGLHYNPITNTFKLGPGVDVNYMLHTQNK
>b2907 ubiH, 2-octaprenyl-6-methoxyphenol--> 2-octaprenyl-6-methoxy-1, 4-benzoquinone
MSVIIVGGGMAGATLALAISRLSHGALPVHLIEATAPESHAHPGFDGRAI
ALAAGTCQQLARIGVWQSLADCATAITTVHVSDRGHAGFVTLAAEDYQLA
ALGQVVELHNVGQRLFALLRKAPGVTLHCPDRVANVARTQSHVEVTLESG
ETLTGRVLVAADGTHSALATACGVDWQQEPYEQLAVIANVATSVAHEGRA
FERFTQHGPLAMLPMSDGRCSLVWCHPLERREEVLSWSDEKFCRELQSAF
GWRLGKITHAGKRSAYPLALTHAARSITHRTVLVGNAAQTLHPIAGQGFN
LGMRDVMSLAETLTQAQERGEDMGDYGVLCRYQQRRQSDREATIGVTDSL
VHLFANRWAPLVVGRNIGLMTMELFTPARDVLAQRTLGWVAR
>b2311 ubiX, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MKRLIVGISGASGAIYGVRLLQVLRDVTDIETHLVMSQAARQTLSLETDF
SLREVQALADVTHDARDIAASISSGSFQTLGMVILPCSIKTLSGIVHSYT
DGLLTRAADVVLKERRPLVLCVRETPLHLGHLRLMTQAAEIGAVIMPPVP
AFYHRPQSLDDVINQTVNRVLDQFAITLPEDLFARWQGA
>b2906 visC, orf, hypothetical protein
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVQEPLAANAPPQLRV
SAINAASEKLLTRLGVWQDILSRRASCYHGMEVWDKDSFGHISFDDQSMG
YSHLGHIVENSVIHYALWNKAHQSSDITLLAPAELQQVAWGENETFLTLK
DGSMLTARLVIGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDA
VARQVFHGEGILAFLPLSDPHLCSIVWSLSPEEAQRMQQASEDEFNRALN
IAFDNRLGLCKVESARQVFPLTGRYARQFASHRLALVGDAAHTIHPLAGQ
GVNLGFMDAAELIAELKRLHRQGKDIGQYIYLRRYERSRKHSAALMLAGM
QGFRDLFSGTNPAKKLLRDIGLKLADTLPGVKPQLIRQAMGLNDLPEWLR
>b0066 yabJ, putative ATP-binding component of a transport system
MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNLIAGFLT
PASGSLTIDGVDHTTMPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGL
KLNAVQQGKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPI
LLLDEPFSALDPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRS
VVVADGRIAWQGMTNELLSGKASASALLGITG
>b0103 yacE, putative DNA repair protein
MRYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGAPALHAI
ADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQI
QQATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTRE
HVEQILAAQATREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQF
VSQEKP
>b0276 yagJ, orf, hypothetical protein
MEARVTVAGMGLVMEVQDYFDGEADRLAKAWLAEYTPQIKSLKDERKEAY
RQIVEMSTEPQDVDLVRPANKFEMTRVREGEKEADLPVWKHHLLCDESGN
YPALLNHWETKVFEIETKREGFAFWYRNPQYTGQSSLGIAYVEAEQYKIV
RPDFLFFAEQDGKMVVDLVDPHSLHLADALPKLEGLALYAEHHSDAYRRI
ESVAEVKGKLRVLDLKRQDVQDAVATAENAETLFSSGLADDYQ
>b0614 ybdU, orf, hypothetical protein
MHLLPELASHHAVSIPELLVSRDERQARQHVWLKRHPVPLVSFTVVAPGP
IKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAP
ARDLKLATIELEHSHPLGRLWDIDVLTPEGEILSRRDYSLPPRRCLLCEQ
SAAVCARGKTHQLTDLLNRMEALLNDVDACNVN
>b1033 ycdW, putative dehydrogenase
MRINFAQRFSGVSMDIIFYHPTFDTQWWIEALRKAIPQARVRAWKSGDND
SADYALVWHPPVEMLAGRDLKAVFALGAGVDSILSKLQAHPEMLNPSVPL
FRLEDTGMGEQMQEYAVSQVLHWFRRFDDYRIQQNSSHWQPLPEYHREDF
TIGILGAGVLGSKVAQSLQTWRFPLRCWSRTRKSWPGVQSFAGREELSAF
LSQCRVLINLLPNTPETVGIINQQLLEKLPDGAYLLNLARGVHVVEDDLL
AALDSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHVAAITRPAEAVE
YISRTIAQLEKGERVCGQVDRARGY
>b1325 ycjG, putative muconate cycloisomerase I (EC 5.5.-.-)
MRLIRRPPRQQGVKMRTVKVFEEAWPLHTPFVIARGSRSEARVVVVELEE
EGIKGTGECTPYPRYGESDASVMAQIMSVVPQLEKGLTREELQKILPAGA
ARNALDCALWDLAARRQQQSLADLIGITLPETVITAQTVVIGTPDQMANS
ASTLWQAGAKLLKVKLDNHLISERMVAIRTAVPDATLIVDANESWRAEGL
AARCQLLADLGVAMLEQPLPAQDDAALENFIHPLPICADESCHTRSNLKA
LKGRYEMVNIKLDKTGGLTEALALATEARAQGFSLMLGCMLCTSRAISAA
LPLVPQVSFADLDGPTWLAVDVEPALQFTTGELHL
>b1667 ydhR, protein ofunknown function
MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTESEKNHEA
GGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKL
A
>b2273 yfbN, orf, hypothetical protein
MEWLSEIRKLRKNVPVGIQVARRLLERTGGDVDEAIKLFHIDQINILTAK
ADVTHQEAENVLLATNYDIAEALRRIDEQRYTLTELILRKNKDAGDALNN
IALAIEYEWDLKRKFWFGFADIQLLPPVLQTFMLVYEWHEYVGWEGMECG
IFFESDHTHQQLQALGLLELAQKMVTARIRYDELKDKAENFHEITEDDIF
KMLIIHCDQLAREVDSILLQFVKDNIDVFPCRHNRHEL
>b2373 yfdU, probable oxalyl-CoA decarboxylase
MSDQLQMTDGMHIIVEALKQNNIDTIYGVVGIPVTDMARHAQAEGIRYIG
FRHEQSAGYAAAASGFLTQKPGICLTVSAPGFLNGLTALANATVNGFPMI
MISGSSDRAIVDLQQGDYEELDQMNAAKPYAKAAFRVNQPQDLGIALARA
IRVSVSGRPGGVYLDLPANVLAATMEKDEALTTIVKVENPSPALLPCPKS
VTSAISLLAKAERPLIILGKGAAYSQADEQLREFIESAQIPFLPMSMAKG
ILEDTHPLSAAAARSFALANADVVMLVGARLNWLLAHGKKGWAADTQFIQ
LDIEPQEIDSNRPIAVPVVGDIASSMQGMLAELKQNTFTTPLVWRDILNI
HKQQNAQKMHEKLSTDTQPLNYFNALSAVRDVLRENQDIYLVNEGANTLD
NARNIIDMYKPRRRLDCGTWGVMGIGMGYAIGASVTSGSPVVAIEGDSAF
GFSGMEIETICRYNLPVTIVIFNNGGIYRGDGVDLSGAGAPSPTDLLHHA
RYDKLMDAFRGVGYNVTTTDELRHALTTGIQSRKPTIINVVIDPAAGTES
GHITKLNPKQVAGN
>b2765 ygcM, putative 6-pyruvoyl tetrahydrobiopterin synthase
MMSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTG
WIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVV
PLLSAVMVKETCTAGCIYRGE
>b2812 ygdL, putative enzyme
MSVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALA
RTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPEC
RVTVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLV
TTGGAGGQIDPTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLG
VDCVFSTEALVYPQSDGTVCAMKATAEGPKRMDCASGFGAATMVTATFGF
VAVSHALKKMMAKAARQG
>b2912 ygfA, putative ligase
MIRQRRRALTPEQQQEMGQQAATRMMTYPPVVMAHTVAVFLSFDGELDTQ
PLIEQLWRAGKRVYLPVLHPFSAGNLLFLNYHPQSELVMNRLKIHEPKLD
VRDVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQHYKTQPVG
YAHDCQLVEKLPVEEWDIPLPAVVTPSKVWEW
>b2928 yggC, putative kinase
MKIELTVNGLKIQAQYQNEEIENVHKPLLHMLAALQTVNPQRRTVVFLCA
PPGTGKSTLTTFWEYLAQQDPELPAIQTLPMDGFHHYNSWLDAHQLRPFK
GAPETFDVAKLTENLRQVVEGDCTWPQYDRQKHDPVEDALHVTAPLVIVE
GNWLLLDDEKWLELASFCDFSIFIHAPAQILRERLISRKIAGGLTRQVAE
AFYARTDGPNVERVLMNSRQANLIVEMTEEGRYHFTS
>b2955 yggW, putative oxidase
MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLDND
VAYAQGREVKTIFIGGGTPSLLSGPAMQTLLDGVRARLPLAADAEITMEA
NPGTVEADRFVDYQRAGVNRISIGVQSFSEEKLKRLGRIHGPQEAKRAAK
LASGLGLRSFNLDLMHGLPDQSLEEALGDLRQAIELNPPHLSWYQLTIEP
NTLFGSRPPVLPDDDALWDIFEQGHQLLTAAGYQQYETSAYAKPGYQCQH
NLNYWRFGDYIGIGCGAHGKVTFPDGRILRTTKTRHPRGFMQGRYLESQR
DVEATDKPFEFFMNRFRLLEAAPRVEFIAYTGLCEDVIRPQLDEAIAQGY
LTECADYWQITEHGKLFLNSLLELFLAE
>b3058 ygiG, putative kinase
MMDIVFIEQLSVITTIGVYDWEQTIEQKLVFDIEMAWDNRKAAKSDDVAD
CLSYADIAETVVSHVEGARFALVERVAEEVAELLLARFNSPWVRIKLSKP
GAVARAANVGVIIERGNNLKENN
>b3712 yieE, orf, hypothetical protein
MERKMATHFARGILTEGHLISVRLPSQCHQEARNIPPHRQSRFLASRGLL
AELMFMLYGIGELPEIVTLPKGKPVFSDKNLPSFSISYAGNMVGVALTTE
GECGLDMELQRATRGFHSPHAPDNHTFSSNESLWISKQNDPNEARAQLIT
LRRSVLKLTGDVLNDDPRDLQLLPIAGRLKCAHVNHVEALCDAEDVLVWS
VAVTPTIEKLSVWELDGKHGWKSLPDIHSRANNPTSRMMRFAQLSTVKAF
SPN
>b1593 ynfK, putative dethiobiotin synthetase
MELVMLKRFFITGTDTSVGKTVVSRALLQALASQGKTVAGYKPVAKGSKE
TPEGLRNKDALVLQSVSTIELPYEAVNPIALSEEESSVAHSCPINYTLIS
NGLANLTEKVDHVVVEGTGGWRSLMNDLRPLSEWVVQEQLPVLMVVGIQE
GCINHALLTAQAIANDGLPLIGWVANRINPGLAHYAEIIDVLGKKLPAPL
IGELPYLPRAEQRELGQYIRLAMLRSVLAVDRVTV
>b2214 yojL, orf, hypothetical protein
MEISFTRVALLAAALFFVGCDQKPQPAKTHATEVTVLEGKTMGTFWRASI
PGIDAKRSAELKEKIQTQLDADDQLLSTYKKDSALMRFNDSQSLSPWPVS
EAMADIVTTSLRIGAKTDGAMDITVGPLVNLWGFGPEQQPVQIPSQEQID
AMKAKTGLQHLTVINQSHQQYLQKDLPDLYVDLSTVGEGYAADHLARLME
QEGISRYLVSVGGALNSRGMNGEGLPWRVAIQKPTDKENAVQAVVDINGH
GISTSGSYRNYYELDGKRLSHVIDPQTGRPIEHNLVSVTVIAPTALEADA
WDTGLMVLGPEKAKEVVRREGLAVYMITKEGDSFKTWMSPQFKSFLVSEK
N