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# Escherichia coli O157:H7 EDL933, EDL933

>Z4385 putative ATP-binding protein of ABC transporter family
MAHNAKGQGLILDNVSAGYHKKIIVDGVSFSVPTEKMTVLVGANGCGKST
LLSTIARVLQPMGGSILLDGKAIHEQPTKALSRRLGILPQSPLLPEGLTV
YELVSRGRFPWQNFIRQWSDADEQAVEEALKLTGTQEFAHLPVEKLSGGQ
RQRCWIAMVLAQKTPYILLDEPTTWLDLRYQVEILELLHDLTRHHGRTVV
VVLHDLNFAVNYGDTLIFLRQGKVVRVLNEGEHCTPELVKAVFDVDVHAS
INTLTGKPFFMPFRGVEKV
>Z4273 putative kinase
MKIELTVNGLNVQAQYHDEEIERVHKPLLRMLAALQTVNPQRRTVVFLCA
PPGTGKSTLTTFWAYLAQQDPELPAIQTLPMDGFHHYNSWLDAHQLRPFK
GAPETFDVAKLAENLRQVVEGDCTWPQYDRQKHDPVEDALHVTAPIIIVE
GNWLLLDDDNWRQLAQFCDFSIFINAPATALRERLVGRKLAGGLSLADAE
AFYDRTDGPNVRRVLEESLPANLTLMMTATGEYRLVD
>Z0665 
MEHQRKLFQQRGYSEDLLPKTQSQRTWKTFNYFTLWMGSVHNVPNYVMVG
GFFILGLSTFSIMLAIILSAFFIAAVMVLNGAAGSKYGVPFAMILRASYG
VRGALFPGLLRGGIAAIMWFGLQCYAGSLACLILIGKIWPGFLTLGGDFT
LLGLSLPGLITFLLFWLVNVGIGFGGGKVLNKFTAILNPCIYIVFGGMAI
WAISLVGLGPIFDYIPSGIQKAENSGFLFLVVINAVVAVWAAPAVSASDF
TQNAHSFREQALGQTLGLVVAYILFAVAGVCIIAGASIHYGADTWNVLDI
VQRWDSLFASFFAVLVILMTTISTNATGNIIPAGYQIAAIAPTKLTYKNG
VLIASIISLLICPWKLMENQDSIYLFLDIIGGMLGPVIGVMMAHYFVVMR
GQINLDELYTAPGDYKYYDNGFNLTAFSVTLVAVILSLGGKFIPLMEPLS
RVSWFVGVIVAFA
>Z0516 
MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQVKDENIT
VVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNG
LAHVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINV
LKAIKA
>Z0055 dihydrofolate reductase type I; trimethoprim resistance
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTRESI
GRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVY
EQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHS
YCFEILERR
>Z4047 putative decarboxylase
MKLIVGMTGATGAXLGVALLQALREMPNVETHLVMSKWAKTTIELETPYS
ARDVAALADFSHNPADQAATISSGSFRTDGMIVIPCSMKTLAGIRAGYAD
GLVGRAADVVLKEGRKLVLVPREMPLSTIHLENMLALSRMGVAMVPPMPA
FYNHPETVDDIVHHVVARVLDQFGLEHPYARRWQGLPQARNFSQENE
>Z1964 putative iron compound ABC transporter, ATP-binding protein
MTLLAVRHASLGYSRHPVLRDVSFTLSQGTICCLLGANGCGKTTLMRSIL
GVIPLLKGEVLLDSLPVQTLSHRQRAQAIAWVPQAHDGIFAFSVLDMVLM
GLAPTIGAFSVPGKQERLKATEQLEKLGILHLAARRWNTLSGGERQLALI
ARALVQQPRLLLLDEPASSLDFGHQIQLLDTLAQLKNNGMTMLMSTHHPL
HANAIADSIIQVEPDGRVTQGLPTEQLTTNKLAALYRVSADQIHHHLSAI
SH
>Z4046 orf; hypothetical protein
MAFDDLRSFLQALDDHGQLLKISEEVNAEPDLAAAANATGRIGDGAPALW
FDNIRGFTDARVAMNTIGSWQNHAISLGLPPNTPVKKQIDEFIRRWDNFP
IAPERRANPAWAQNTVDGDEINLFDILPLFRLNDGDGGFYLDKACVVSRD
PLDPDNFGKQNVGIYRMEVKGKRKLGLQPVPMHDIALHLHKAEERGEDLP
IAITLGNDPIITLMGATPLKYDQSEYEMAGALRESPYPIATAPLTGFDVP
WGSEVILEGVIESRKREIEGPFGEFTGHYSGGRNMTVVRIDKVSYRTRPI
FESLYLGMPWTEIDYLMGPATCVPLYQQLKAEFPEVQAVNAMYTHGLLAI
ISTKKRYGGFARAVGLRAMTTPHGLGYVKMVIMVDEDVDPFNLPQVMWAL
SSKVNPAGDLVQLPNMSVLELDPGSSPAGITDKLIIDATTPVAPDNRGHY
SQPVVDLPETKAWAEKLTAMLAARK
>Z4867 
MYRIVLGKVSTLSAAPLPPGLREQAPQGPRRERWLAGRALLSHTLSPLPE
IIYGEQGKPAFAPETPLWFNLSHSGDDIALLLSDEGEVGCDIEVIRPRAN
WRWLANAVFSLGEHAEMDAVHPDQQLEMFWRIWTRKEAIVKQRGGSAWQI
VSVDSTYHSSLSVSHCQLENLSLAICTPTPFTLTADSVQWIDSVN
>Z2694 orf, hypothetical protein
MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTESEKNHEA
GGIYLFTDEKSALAYLEKHTAQLKKLGVEEVVAKVFDVNEPLSQINQAKL
A
>Z2431 partial putative pump protein; disrupted by IS629
MVIPENGILRDPINHTVMPSPFIKGIVPLIILFFFVVSLAYGIATRTIRR
QADLPHLMIEPMKEMAGFIVMVFPLAQFVAMFNWSNMGKFIAVGLTDILE
SSGLSGIPAFVGLALLSSFLCMFIASGSAIWSILAPIFVPMFMLLGFHPA
FAQILFRIADSSVLPLAPVSPFVPLFLGFLQRYKPDAKLGTYYSLVLPYP
LIFLVVWLLMLLAWYLVGLPIGPGIYPRLS
>Z3390 putative hydroxylase
MTKVTRAVIVGGGIGGAATALSLARLGIKVVLLEKAHEIGEIGAGIQLGP
NAFSALDSLGVGEVARQRAVFTDHITMMDAVNAEEVVCIETGQAFRDHFG
GPYAVIHRVDIHASVWEAVLTHPDVEYHTSTNVVDIRETEDDVTVFDDRG
NSWTGDILIGCDGVKSVVRQSLLGDAPRVTGHVVYRAVIDRADMPEDLRI
NAPVLWAGPHCHLVHYPLRGGKQYNLVVTFHSRQQEEWGVKDGSKEEVLS
YFEGIHPRPRQMLDKPTSWRRWSTADREPVAKWGTKRITLVGDSAHPVAQ
YMAQGACMALEDAVTLGKALAQCEGDAAQAFALYESVRIPRTARIVWSTR
EMGRVYHAAGVERQVRNLLWKGKSQAEFYRGMEWLYGWKEDNCLQPR
>Z2392 unknown protein encoded within prophage CP-933R
MATLTKKERAWLNELQEVLDRCPSPKKIGFYTIGDKSIYLYDLRRMDEIM
EALDNRSSMDWCVAVHDMNAGFDEKILFPSSVESTAG
>Z2428 partial putative pump protein; disrupted by IS629
MSMSSIPSSSQSGKLYGWVERIGNKVPHPFLLFIYLIIVLMVTTAILSAF
GVSAKNPTDGTPVVVKNLLSVEGLHWFLPNVIKNFSGFAPLGAILALVLG
AGLAERVGLLPALMVKMASHVNARYASYMVLFIAFFSHISSDAALVIMPP
MGALIFLAVGRHPVAGLLAAIAGVGCGFTANLLIVTTDVLLSGISTEAAA
AFNPQMHVSVIDNWYFMASSVVVLTIVGGLITDKIIEPRLGQWQGNSDEK
LQTLTEMNRPGNPGD
>Z0886 putative corrinoid:ATP adenosyltransferase
MEARISTERHVQRQQKLKEQVDTRVAAAIEKKGILIVFTGNGKGKSTAAF
GTVTRAVGHGKTVGVAQYIKGQWDNGEYNLLQPLGVEFHIMGTGFTWETQ
NRQADIDAAKEVWSESKRMLADKRYDLVVLDELTYMLAYHYLDTEEVIAS
LQNRPAQQSVIVTGRGCHSQILKMADTVSEIRPVKHAFDNGIQAQPGIDW
>Z3637 putative enzyme
MSDQLQMTDGMHIIVEALKQNNIDTIYGVVGIPVTDMARHAQAEGIRYIG
FRHEQSAGYAAAASGFLTQKPGICLTVSAPGFLNGLTALANATVNGFPMI
MISGSSDRAIVDLQQGDYEELDQMNAAKPYAKAAFRVNQPQDLGIALARA
IRVSVSGRPGGVYLDLPANVLAATMEKDEALTTIVKVENPSPALLPCPKS
VTSAISLLAKAERPLIILGKGAAYSQADEQLREFIESAQIPFLPMSMAKG
ILEDTHPLSAAAARSFALANADVVMLVGARLNWLLAHGKKGWAADTQFIQ
LDIEPQEIDSNRPIAVPVVGDIASSMQGMLAELKQNTFTTPLVWRDILNI
HKQQNAQKMHEKLSTDTQPLNYFNALSAVRDVLRENQDIYLVNEGANTLD
NARNIIDMYKPRRRLDCGTWGVMGIGMGYAIGASVTSGSPVVAIEGDSAF
GFSGMEIETICRYNLPVTIVIFNNGGIYRGDGVDLSGAGAPSPTDLLHHA
RYDKLMDAFRGVGYNVTTTDELRHALTTGIQSRKPTIINVVIDPAAGTES
GHITKLNPKQVAGN
>Z2585 orf, hypothetical protein
MELVMLKRFFITGTDTSVGKTVVSRALLQALASQGKTVAGYKPVAKGSKE
TPEGLRNKDALVLQSVSTIELPYEAVNPIALSEEESSVAHSCPINYTLIS
NGLANLTEKVDHVVVEGTGGWRSLMNDLRPLSEWVVQEQLPVLMVVGIQE
GCINHALLTAQAIANDGLPLIGWVANRINPGLAHYAEIIDVLGKKLPAPL
IGELPYLPRAEQRELGQYIRLAMLRSVLAVDRVTV
>Z0528 apbA, involved in thiamin biosynthesis, alternative pyrimidine biosynthesis
MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVETDGSIFN
ESLTANDPDFLATSDLLLVTLKAWQVSDAVKSLASTLPVTTPILLIHNGM
GTIEELQNIQQPLLMGTTTHAACRDGNVIIHVANGITHIGPARQQDGDYS
YLADILQTVLPDVAWHNNIRAELWRKLAVNCVINPLTAIWNCPNGELRHH
PQEIMQICEEVAAVIEREGHHTSAEDLRDYVMQVIDATAENISSMLQDIR
TLRHTEIDYINGFLLRRARAHGIAVPENTRLFEMVKRKESEYERIGTGLP
RPW
>Z0993 bioA, 7,8-diaminopelargonic acid synthetase
MTTDDLAFDQRHIWHPYTSMTSPLPVYPVASAEGCELILSDGRRLVDGMS
SWWAAIHGYNHPQLNAAMKSQIDAMSHVMFGGITHAPAIELCRKLVAMTP
QPLECVFLADSGSVAVEVAMKMALQYWQAKGEARQHFLTFRNGYHGDTFG
AMSVCDPDNSMHSLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAA
HRHEIAAVIIEPIVQGAGGMRMYHPEWLKRIRKMCDREGILLIADEIATG
FGRTGKLFACEHAEIAPDILCLGKALTGGTMTLSATLTTREVAETISNGE
AGCFMHGPTFMGNPLACAAANASLAILESGDWQQQVAAIEVXLREQLAPA
RDAEMVADVRVLGAIGVVETTRPVNMAALQKXFVEQGVWIRPFGKLIYLM
PPYIILPQQLQRLTAAVNRAVQDETFFCQ
>Z0994 bioB, biotin synthesis, sulfur insertion?
MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKT
GACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGA
AWKNPHERDMSYLEQMVQGVKAMGLXACMTLGTLSESQAQRLANAGLDYY
NHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVK
DRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVA
RIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDK
DLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL
>Z0997 bioD, dethiobiotin synthetase
MSKRYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGSEKTPEG
LRNSDALALQRNSSLQLDYATVNPYTFAEPTSPHIISAQEGRSIESSVMS
SGLRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKL
GCINHAMLTAQAIQHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPL
LGESPWLAENPENAATGKYINLALL
>Z0995 bioF, 8-amino-7-oxononanoate synthase
MSWQEKINAALDARRAADALRRRYPVAQGAGRWLVADDRQYLNFSSNDYL
GLSHHPQIIRAWKQGAEQFGVGSGGSGHVSGYSVAHQALEEELAEWLGYS
RALLFISGFAANQAVIAAMMAKEDRIVADRLSHASLLEAASLSPSQLRRF
VHNDVTHLARLLASPCPGQQLVVTEGVFSMDGDSAPLAEIQQVTQQHNGW
LMVDDAHGTGVIGEQGRGTCWLQKVKPELLVVTFGKGFGVSGAAVLCSST
VADYLLQFARHLIYSTSMPPAQAQALRASLAVIRSDEGDARREKLAALIT
RFRAGVQDLPFTLADSCSAIQPLIVGDNSRALQLAEKLRQQGCWVTAIRP
PTVPXGTARLRLTLTAAHEMQDIDRLLEVLHGNG
>Z5527 btuB, outer membrane receptor for transport of vitamin B12, E colicins, and bacteriophage BF23
MIKKASLLTACSVTAFSAWAQDTSPDTLVVTANRFEQPRSTVLAPTTVVT
RQDIDRWQSTSVNDVLRRLPGVDITQNGGSGQLSSIFIRGTNASHVLVLI
DGVRLNLAGGSGSADLSQFPIALVQRVEYIRGPRSAVYGSDAIGGVVNII
TTRDEPGTEISAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDYAHTHGYDV
VAYGNTGTQAQPDNDGFLSKTLYGALEHNFTDAWSGFVRGYGYDNRTNYD
AYYSPGSPLVDTRKLYSQSWDAGLRYNGELIKSQLITSYSHSKDYNYDPH
YGRYDSSATLDEMKQYTVQWANNIIIGHGNVGAGVDWQKQSTAPGTAYVK
DGYDQRNTGIYLTGLQQVGDFTFEGAARSDDNSQFGRHGTWQTSAGWEFI
EGYRFIASYGTSYKAPNLGQLYGFYGNPNLDPEKSKQWEGAFEGLTAGVN
WRISGYRNDVSDLIDYDDHTLKYYNEGKARIKGVEATANFDTGPLTHTVS
YDYVDARNAITDTPLLRRAKQQVKYQLDWQLYDFDWGITYQYLGTRYDKD
YSSYPYQTVKMGGVSLWDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQ
TAGREYTLSGSYTF
>Z2740 btuC, vitamin B12 transport permease protein
MLTLARQQQRQNIRWLLCLSVLMLLALLLSLCAGEQWISPGDWFSPRGEL
FVWQIRLPRTLAVLLVGAALAISGAVMQALFENPLAEPGLLGVSNGAGVG
LIAAVLLGQGQLPNWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGV
ALGIICSALMTWAIYFSTSVDLRQLMYWMMGGFGGVDWRQSWLMLALIPM
LLWICCQSRPMNMLALGEISARQLGLPLWFWRNVLVAATGWMVGVSVALA
GAIGFIGLVIPHILRLCGLTDHRALLPGCALAGASALLLADIVARLALAA
AELPIGVVTATLGAPVFIWLLLKAGR
>Z2738 btuD, ATP-binding component of vitamin B12 transport system
MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLARMAGMT
SGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFAMPVWHYLTLHQHD
KTRTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANP
AGQLLLLDEPMNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHA
HRAWLLKGGKMLASGRREDVLTPPNLAQAYGMNFRRLDIEGHRMLISTI
>Z2540 btuR, cob(I)alamin adenolsyltransferase
MSDERYQQRQQRVKEKVDARMAQAQDERGIIIVFTGNGKGKTTAAFGTAT
RAVGHGKKVGVVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWDTQNRES
DTAACREVWQHAKRMLADSSLDLVLLDELTYMVAYDYLPLEEVLQALNER
PHQQTVIITGRGCHRDILELADTVSELRPVKHAFDAGVKAQIGIDY
>Z4914 chuW, putative oxygen independent coproporphyrinogen III oxidase
MNANNTLDLTPHFALDGDQPFKDRRAMMPFRGAIPVAKEQLAQTWQEMIN
QTASPRKRLVYLHIPFCATHCTFCGFYQNRFNEDACAHYTDALIREIEME
ADSVLHQSAPIHAVYFGGGTPSALSAHDLARIITTLREKLPLAPDCEITI
EGRVLNFDAERIDACLDAGANRFSIGIQSFNSKIRKKMARTSDGPTAIAF
MESLVKRDRAAVVCDLLFGLPGQDAQTWGEDLAIARDIGLDGVDLYALNV
LSNTPLGKAVENGRTTVPSPAERRDLYLQGCDFMDDAGWRCISNSHWGRT
TRERNLYNLLIKQGADCLAFGSGAGGSINGYSWMNERNLQTWHESVAAGK
KPLMLIMRNAERNAQWRHTLQSGVETARVPLDELTPHAEKLAPLLAQWHQ
KGLSRDASTCLRLTNEGRFWASNILQSLNELIQVLNAPAIMREKP
>Z0757 citG, orf, hypothetical protein
MSMPATLTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAH
KDMALEDFHRSALAIQGWLPRFIEFGACSAEMAPEAVLHGLRPIGMACEG
DMFRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQLLTPTTVCSTAASFCR
GLTDRELRTNNSQLTAGQRLYQQLGLTGARGEAEAGYPLVINHALPHYLT
LLDQGLDPELALLDTLLLLMAINGDTNVASRGGEGGLRWLQREAQTLLQK
GGIRTPADLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI
>Z5545 coaA, pantothenate kinase
MTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINEDLSLEEVAEIYLPL
SRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKSTTARVL
QALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVK
FVSDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGM
DYPHDPHHVFVSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSY
FHNYAKLTKEEAIKTAMTLWKEINWLNLKQNILPTRERASLILTKSANHA
VEEVRLRK
>Z3152 cobS, cobalamin 5'-phosphate synthase
MSKLFWAMLSFITRLPVPRRWSQGLDFEHYSRGIITFPLIGLLLGAISGL
VFMVLQAWCGAPLAALFSVLVLVLMTGGFHLDGLADTCDGVFSARSRDRM
LEIMRDSRLGTHGGLALIFVVLAKILVLSELALRGEPILASLAAACAVSR
GTAALLMYRHRYAREEGLGNVFIGKIDGRQTCVTLGLAAIFAAVLLPGMH
GVAAMVVTMVAIFILGQLLKRTLGGQTGDTLGAAIELGELVFLLALL
>Z3151 cobT, nicotinate-nucleotide dimethylbenzimidazole-P phophoribosyl transferase
MQTLANLLNTIPAIDPAAMSRAQRHIDGLLKPVGSLGRLEALGVQLAGMP
GLNGIPHVGKKAVLVMCADHGVWEEXVAISPKEVTAIQAENMTRGTTGVC
VLAAQAGANVHVIDVGIDTAEPIPGLINMRVARXSGNIASAPAMSRRQAE
KLLLDVICYTRELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVV
GIGANLPTDKLANKIDVVRRAITLNQPNPQDGVNVLAKVGGFDLVGMAGV
MLGAASCGLPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIA
LSHLGLEPFLNMDMRLGEGSGAALAMPIIEAACAIYNNMGELAASKIVLP
GNTTSDLNS
>Z3153 cobU, cobinamide kinase/cobinamide phosphate guanylyltransferase
MMILVTGGARSGKSRHAEALIGDSSQVLYIATSQILDDEMAARIEHHRQG
RPEHWRTVERWQHLDELIHADINPNEVVLLECVTTMVTNLLFDYGGDKDP
DEWDYQAMEQAINAEIQSLIAACQRCPAKVVLVTNEVGMGIVPESRLARH
FRDIAGRVNQQLAAAANEVWLVVSGIGVKIK
>Z4060 cysD, ATP:sulfurylase (ATP:sulfate adenylyltransferase), subunit 2
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKA
FYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHQNPEGVAMGI
NPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYS
FRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWL
ENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLG
CWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQG
YF
>Z4729 cysG, uroporphyrinogen III methylase; sirohaeme biosynthesis
MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFT
AWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFC
NVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLH
LGQVAKYAGQLRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAI
TETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADVVVYDRL
VSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLK
GGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYA
QSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEHGMP
GEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDK
LNWFSNH
>Z4072 cysH, 3'-phosphoadenosine 5'-phosphosulfate reductase
MSKLDLNALNELPKVDRILALAETNAQLEKLDAEGRVAWALDNLPGEYVL
SSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLN
LKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQ
TWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKNGLK
YHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>Z5063 dfp, flavoprotein affecting synthesis of DNA and pantothenate metabolism
MKARQQKYCDKIANFWCHPTGKIIMSLAGKKIVLGVSGGIAAYKTPELVR
RLRDRGADVRVAMTEAAKAFITPLSLQAVSGYPVSDSLLDPAAEAAMGHI
ELGKWADLVILAPATADLIARVAAGMANDLVSTICLATPAPVAVLPAMNQ
QMYRAAATQHNLEVLASRGLLIWGPDSGSQACGDIGPGRMLDPLTIVDMA
VAHFSPVNDLKHLNIMITAGPTREPLDPVRYISNHSSGKMGFAIAAAAAR
RGANVTLVSGPVSLPTPPFVKRVDVMTALEMEAAVNASVQQQNIFIGCAA
VADYRAATVAPEKIKKQATQGDELTIKMVKNPDIVAGVAALKDHRPYVVG
FAAETNNVEEYARQKRIRKNLDLICANDVSQPTQGFNSDNNALHLFWQDG
DKVLPLERKELLGQLLLDEIVTRYDEKNRR
>Z0523 dxs, 1-deoxyxylulose-5-phosphate synthase; flavoprotein
MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVSRSSGHF
ASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQ
KGGLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVI
GDGAITAGMAFEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLL
SGKLYSSLREGGKKVFSGVPPIKELLKRTEEHIKGMVVPGTLFEELGFNY
IGPVDGHDVLGLITTLKNMRDLKGPQFLHIMTKKGRGYEPAEKDPITFHA
VPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAAKDNKLMAITPAMREGS
GMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIYSTFLQRAY
DQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMT
PSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVK
RRGEKLAILNFGTLMPEAAKVAESLNATLVDMRFVKPLDETLILEMAASH
EALVTVEENAIMGGAGSGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEM
RAELGLDAAGMEAKIKAWLA
>Z0735 entC, isochorismate hydroxymutase 2, enterochelin biosynthesis
MDTSLAEEVQQTMATLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPD
SPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQ
EKQASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVL
SRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLL
RKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMK
EVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHP
TPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAK
LRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH
>Z0729 fepC, ATP-binding component of ferric enterobactin transport
MTESVARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLL
RTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNATTLGDITVQE
LVARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQ
RAWIAMVLAQETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAV
LHDLNQACRYASHLIALREGKIVAQGAPKEIVTAELIERIYGLRCMIIDD
PVAGTPLVVPLGRTAPSTANS
>Z0162 fhuC, ATP-binding component of hydroxymate-dependent iron transport
MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGK
STLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGM
TVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSG
GERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLT
VIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIYGIPMG
ILPHPAGAAPVSFVY
>Z3577 folC, dihydrofolate:folylpolyglutamate synthetase; dihydrofolate synthetase
MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSQVAARLGVLKPAPF
VFTVAGTNGKGTTCRTLESILMAAGYKVGVYSSPHLVCYTERVRVQGQEL
PESAHTASFAEIESARGDISLTYFEYGTLSALWLFKQAQLDVVILEVGLG
GRLDATNIVDADVAVVTSIALDHTDWLGPDRESIGREKAGIFRSEKPAIV
GEPEMPSTIADVAQEKGALLQRRGVEWNYSVTDHDWAFSDAHGTLENLPL
PLVPQPNAATALAALRASGLEVSENAIRDGIASAILPGRFQIVSESPRVI
FDVAHNPHAAEYLTGRMKTLPKNGRVLAVIGMLHDKDIAGTLAWLKSVVD
DWYCAPLEGPRGATAEQLLEHLGNGKSFDSVAQAWDAAMADAKAEDTVLV
CGSFHTVAHVMEVIDARRSGGK
>Z0684 folD, 5,10-methylene-tetrahydrofolate dehydrogenase; 5,10-methylene-tetrahydrofolate cyclohydrolase
MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIY
VASKRKACEEVGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLP
LPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLL
ERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHV
ENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAA
KRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQGE
>Z3409 folE, GTP cyclohydrolase I
MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHMTEIMQL
LNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMV
TVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQ
VQERLTQQILIALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSL
GGLFKSSQNTRHEFLRAVRHHN
>Z0153 folK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokin ase
MTVAYIAIGSNLASPLEQVNAALKALGDIPESHILTVSSFYRTPPLGPQD
QPDYLNAAVALETTLAPEELLNHTQQIELQQGRVRKAERWGPRTLDLDIM
LFGNETINTERLTVPHYDMKNRGFMLWPLFEIAPELVFPDGETLREILTS
LAVLQPAIWY
>Z4539 folP, 7,8-dihydropteroate synthase
MLRGFFLSIHTRDNIMKLFAQGTSLDLSHPHVMGILNVTPDSFSDGGTHN
SLIDAVKHANLMINAGATIIDVGGESTRPGAAEVSVEEELQRVIPVVEAI
AQRFEVWISVDTSKPEVIRESAKVGAHIINDIRSLSEPGALEAAAETGLP
VCLMHMQGNPKTMQEAPKYDDVFAEVNRYFIEQIARCEQAGIAKEKLLLD
PGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGMSRKSMIGQLLNVGPSER
LSGSLACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAKENKRYE
>Z3565 folX, D-erythro-7,8-dihydroneopterin tri P epimerase
MAQPAAIIRIKNLRLRTFIGIKEEEINNRQDIVINVTIHYPADKARTSED
INDALNYRTVTKNIIQHVENNRFSLLEKLTQDVLDIAREHHWVTYAEVEI
DKLHALRYADSVSMTLSWQR
>Z3989 gshA, gamma-glutamate-cysteine ligase
MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGS
ALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMW
PLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVH
YNFSLPMAFWQAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGA
SPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLGYTNKSQSNLG
ITFNDLYEYVAGLKQAIKTPSEEYAKIGIDKDGKRLQINSNVLQIENELY
APIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFL
DLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQF
PLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSAR
ILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQ
EMEAADTEPFAVWLEKHA
>Z4292 gshB, glutathione synthetase
MIKLGIVMDPIANINIKKDSSFAMLLEAQRRGYELHYMEMGDLYLINGEA
RAHTRTLNVKQNYEEWFSFVGEQDLPLADLDVILMRKDPPFDTEFIYATY
ILERAEEKGTLIVNKPQSLRDCNEKLFTAWFSDLTPETLVTRNKAQLKAF
WEKHSDIILKPLDGMGGASIFRVKEGDPNLGVIAETLTEHGTRYCMAQNY
LPAIKDGDKRVLVVDGEPVPYCLARIPQGGETRGNLAAGGRGEPRPLTES
DWKIARQIGPTLKEKGLIFVGLDIIGDRLTEINVTSPTCIREIEAEFPVS
ITGMLMDAIEARLQQ
>Z1981 hemA, enzyme in alternate path of synthesis of 5-aminolevulinate
MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLXQPMVQGGVVLSTC
NRTELYLSVEEQDNLQEALIRWLCDYHNLNEEDLRKSLYWHQDNDAVSHL
MRVASGLDSLVLGEPQILGQVKKAFADSQKGHMKASELERMFQKSFSVAK
RVRTETDIGASAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARH
LREHKVQKMIIANRTRERAQILADEVGAEVIALSDIDERLREADIIISST
ASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSV
DDLQSIISHNLAQRKAAAVEAETIVAQETSEFMAWLRAQSASETIREYRS
QAEQVRDELTAKALAALEQGGDAQAIMQDLAWKLTNRLIHAPTKSLQQAA
RDGDNERLNILRDSLGLE
>Z0468 hemB, 5-aminolevulinate dehydratase = porphobilinogen synthase
MHLNSTNIRQTMTDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEE
EIDDYKAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETG
SDAWREDGLVARMSRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVD
NDATLENLGKQAVVAAAAGADFIAPSAAMDGQVQAIRQALDAAGFKDTAI
MSYSTKFASSFYGPFREAAGSALKGDRKSYQMNPMNRREAIRESLLDEAQ
GADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEYAMIKFAALAGAID
EEKVVLESLGSIXRAGADLIFSYFALDLAEKKILR
>Z5319 hemC, porphobilinogen deaminase = hydroxymethylbilane synthase
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVT
RGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGL
GLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDL
IIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISL
PAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQ
VPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>Z5318 hemD, uroporphyrinogen III synthase
MSILVTRPSPAGEELVSRLRTLGQVAWHFPLIEFSPGRQLPQLADQLAAL
GESDLLFALSQHAVAFAQSQLHQQDRKWPRLPNYFAIGRTTALALHTVSG
QKILYPQDREISEVLLQLPELQNIAGKRALILRGNGGRELIGDTLTARGA
EVTFCECYQRCAIHYDGAEEAMRWQSREVTTVVVTSGEMLQQLWSLIPQW
YREHWLLHCRLLVVSERLAKLARELGWQDIKVADNADNDALLRALQ
>Z5572 hemE, uroporphyrinogen decarboxylase
MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAGDFMSLC
KNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFT
SPVTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWT
LATYMVEGGSSKAFTVIKKMMYADPQALHALLDKLAKSVALYLNAQIKAG
AQAVMIFDTWGGVLTGRDYQQFSLYYMHKIVDGLLRENDGRRVPVTLFTK
GGGQWLEAMAETGCDALGLDWTTDIADARRRVGNKVALQGNMDPSMLYAP
PARIEEEVATILAGFGHGEGHVFNLGHGIHQDVPPEHAGVFVXAVHRLSE
QYHR
>Z3701 hemF, coproporphyrinogen III oxidase
MKPDAHQVKQFLLNLQDTICQQLTAVDGAEFVEDSWQREGGGGGRSRVLR
NGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNP
YVPTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEEDAIHWHRTARD
LCLPFGKDVYPRYKKWCDDYFYLKHRNEQRGIGGLFFDDLNTPDFDHCFA
FMQAVGKGYTDAYLPIVERRKAXAYGERERNFQLYRRGRYVEFNLVWDRG
TLFGLQTGGRTESILMSMPPLVRWEYDYQPKDGSPEAALSEFIKVRDWV
>Z5372 hemG, protoporphyrinogen oxidase
MKTLILFSTRDGQTREIASYLASELKELGIQADVANVHRIEEPQWENYDR
VVIGASIRYGHYHSAFQEFVKKHATRLNSMPSAFYSVNLVARKPEKRTPQ
TNSYARKFLMNSQWRPDRCAVIAGALRYPRYRWYDRFMIKLIMKMSGGET
DTRKEVVYTDWEQVANFAREIAHLTDKPTLK
>Z0592 hemH, ferrochelatase: final enzyme of heme biosynthesis
MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLLWWPLLR
GVILPLRSPRVAKLYASVWMEGGSPLMVYSRQQQQALAQRLPETPVALGM
SYGSPSLESAVDELLAEHVDHIVVLPLYPQFSCSTVGAVWDELARILARK
RSIPGISFIRDYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRY
ADEGDDYPQRCRTTTRELASALGMAPEKVMMTFQSRFGREPWLMPYTDET
LKMLGEKGVGHIQVMCPGFAADCLETLEEIAEQNREVFLGAGGKKYEYIP
ALNATPEHIEMMANLVAAYR
>Z0165 hemL, glutamate-1-semialdehyde aminotransferase (aminomutase)
MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGK
AYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVT
ELVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLL
VKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIAC
IIVEPVAGNMNCVPPLPDFLPGLRALCDEFGALLIIDEVMTGFRVALAGA
QDYYGVEPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSG
NPIAMAAGFACLNEVAQPGVHETLDELTTRLAEGLLEAAEEAGIPLVVNH
VGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVYLAPSAFEA
GFMSVAHSMEDINNTIDAARRVFAKL
>Z5403 hemN, O2-independent coproporphyrinogen III oxidase
MSMSVQQIDWDLALIQKYNYSGPRYTSYPTALEFSEDFGEQAFLQAVARY
PERPLSLYVHIPFCHKLCYFCGCNKIVTRQQHKADQYLDALEQEIVHRAP
LFAGRHVSQLHWGGGTPTYLNKAQISRLMKLLRENFQFNADAEISIEVDP
REIELDVLDHLRAEGFNRLSMGVQDFNKEVQRLVNREQDEEFIFALLNHA
REIGFTSTNIDLIYGLPKQTPESFAFTLKRVAELNPDRLSVFNYAHLPTI
FAAQRKIKDADLPSPQQKLDILQETIAFLTQSGYQFIGMDHFARPDDELA
VAQREGVLHRNFQGYTTQGDTDLLGMGVSAISMIGDCYAQNQKELKQYYQ
QVDEQGNALWRGIALTRDDCIRRDVIKSLICNFRLDYAPIEKQWDLHFAD
YFAEDLKLLAPLAKDGLVDVDXKGIQVTAKGRLLIRNICMCFDTYLRQKA
RMQQFSRVI
>Z5317 hemX, uroporphyrinogen III methylase
MTEQEKTSAVVEETREAVDTTSQPVATEKKSKNNTALILSAVAIAIALAA
GVGLYGWGKQQAVNQTATSDALANQLTALQKAQESQKVELEGIIKQQAAQ
LKQANRQQETLAKQLDEVQQKVATISGSDAKTWLLAQADFLVKLAGRKLW
SDQDVTTAAALLKSADASLADMNDPSLITVRRAITDDIASLSAVSQVDYD
GIILKLNQLSNQVDNLRLADNDSDGSPMDSDGEELSSSISEWRINLQKSW
QNFMDNFITIRRRDDTAVPLLAPNQDIYLRENIRSRLLVAAQAVPRHQQE
TYRQALENVSTWVRAYYDTDDATTKAFLDEVDQLSQQNISMDLPETLQSQ
AMLEKLMQTRVRNLLAQPAAGTTEAKPAPAPAPAPAPQADTPAAAPQGE
>Z5316 hemY, a late step of protoheme IX synthesis
MLKVLLLFVLLIAGIVVGPMIAGHQGYVLIQTDNYNIETSVTGLAIILIL
AMVVLFAIEWLLRRIFRTGAHTRGWFVGRKRRRARKQTEQALLKLAEGDY
QQVEKLMAKNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERAAELAGN
DTIPVEITRVRLQLARNENHAARHGVDKLLEVTPRHPEVLRLAEQAYIRT
GAWSSLLDIIPSMAKAHVGDEEHRAMLEQQAWIGLMDQARADNGSEGLRN
WWKNQSRKTRHQVALQVAMAEHLIECDDHDTAQQIIIDGLKRQYDDRLLL
PIPRLKTNNPEQLEKVLRQQIKNVGDRPLLWSTLGQSLMKHGEWQEASLA
FRAALKQRPDAYDYAWLADALDRLHKPEEAAAMRRDGLMLTLQNNPPQ
>Z5165 ilvB, acetolactate synthase I,valine-sensitive, large subunit
MASSGTSSTRKRFTGAEFIVHFLEQQGIKIVTGIPGGSILPVYDALSQST
QIRHILARHEQGAGFIAQGMARTDGKPAVCMACSGPGATNLVTAIADARL
DSIPLICITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVRHIEELPQV
MSDAFRIAQSGRPGPVWIDIPKDVQTAVFEIEAQPAVAEKAVAPAFSEES
IRDAAAMINAAKRPVLYLGGGVINAPARVRELAEKAQLPTTMTLMALGML
PKAHPLSLGMLGMHGVRSTNYILQEADLLIVLGARFDDRAIGKTEQFCPN
AKIIHVDIDRAELGKIKQPHVAIQADVDDVLAQLIPQVEAQPRAEWHQLV
ADXQREFPCPIPKACDPLSHYGLINAVAACVDDNAIITTDVGQHQMWTAQ
AYPLNRPRQWLTSGGLGTMGFGLPAAIGAALANPDRKVLCFSGDGSLMMN
IQEMATASENQLDVKIILMNNEALGLVHQQQSLFYKQGVFAATYPGKINF
MQIAAGFGLETCDLNNEADPQAALQEIINRPGPALIHVRIDAEEKVYPMV
PPGAANTEMVGE
>Z5285 ilvC, ketol-acid reductoisomerase
MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGL
NQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQAD
LVVNLTPDKQHSDVVHTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVV
MVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGG
HRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYA
EKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLF
QKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIG
EQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANT
IARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPE
GAVDNAQLRDLNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG
>Z5281 ilvE, branched-chain amino-acid aminotransferase
MTTKKADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYDSHKGPV
VFRHREHMQRLHDSAKIYRFPVSQSIDELMEACRDVIRKNNLTSAYIRPL
IFVGDVGMGVNPPAGYSTDVIIAAFPWGAYLGAEALEQGIDAMVSSWNRA
APNTIPTAAKAGGNYLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENL
FEVKDGVLFTPPFTSSALPGITRDAIIKLAKELGIEVREQVLSRESLYLA
DEVFMSGTAAEITPVRSVDGIQVGEGRCGPVTKRIQQAFFGLFTGETEDK
WGWLDQVNQ
>Z5279 ilvG, acetohydroxy acid synthase II
MNGAQWVVHALRAQGVNTVFGYPGGAIMPVYDALYDGGVEHLLCRHEQGA
AMAAIGYARATGKTGVCIATSGPGATNLITGLADALLDSIPVVAITGQVS
APFIGTDAFQEVDVLGLSLACTKHSFLVQSLEELPRIMAEAFDVASSGRP
GPVLVDIPKDIQLASGDLEPWFTTVENEVTFPHAEVEQARQMLAKAQKPM
LYVGGGVGMAQAVPALREFLATTKMPATCTLKGLGAVEADYPYYLGMLGM
HGTKAANFAVQECDLLIAVGARFDDRVTGKLNTFAPHASVIHMDIDPAEM
NKLRQAHVALQGDLNALLPALQQPLNINDWQQYCAQLRDEHAWRYDHPGD
AIYAPLLLKQLSDRKPADCVVTTDVGQHQMWAAQHIAHTRPENFITSSGL
GTMGFGLPAAVGAQVARPNDTVVCISGDGSFMMNVQELGTVKRKQLPLKI
VLLDNQRLGMVRQWQQLFFQERYSETTLTDNPDFLKLASAFGIPGQHITR
KDQVEAALDTMLNSDGPYLLHVSIDELENVWPLVPPGASNSEMLEKLS
>Z0087 ilvI, acetolactate synthase III, valine sensitive, large subunit
MSLAANCLSKIGRLMCFTHFFRQTVRQAMEMLSGAEMVVRSLIDQGVKQV
FGYPGGAVLDIYDALHTVGGIGHVLVRHEQAAVHMADGLARATGEVGVVL
VTSGPGATNAITGIATAYMDSIPLVVLSGQVATSLIGYDAFQECDMVGIS
RPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVDLPKDILNPANKL
PYVWPESVSMRSYNPTTTGHKGQIKRALQTLVAAKKPVVYVGGGAITAGC
HQQLKETVEALNLPVVSSLMGLGAFPATHRQALGMLGMHGTYEANMTMHN
ADVIFAVGVRFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVTADIPIVG
DARQVLEQMLELLSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSEKI
KPQAVIETLWRLTKGGAYVTSDVGQHQMFAALYYPFDKPRRWINSGGLGT
MGFGLPAALGVKMALPEETVVCVTGDGSIQMNIQELSTALQYELPVLVVN
LNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLAEAYGHVGIQISHPQ
ELESKLSEALEQVRNNRLVFVDVTVDGSEHVYPMQIRGGGMDEMWLSKTE
RT
>Z0524 ispA, geranyltranstransferase (farnesyldiphosphate synthase)
MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGGKRLRPF
LVYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPT
CHVKFGEANAILAGDALQTLAFSILSDADMPEVSDRDRISMISELASASG
IAGMCGGQALDLDAEGKHVPLDALERIHRHKTGALIRAAVRLGALSAGDK
GRRALPVLDKYAESIGLAFQVQDDILDVVGDTATLGKRQGADQQLGKSTY
PALLGLEQARKKAQDLIDDARQSLKQLAEQSIDTSALEALADYIIQRNK
>Z4550 ispB, octaprenyl diphosphate synthase
MNLEKINELTAQDMAGVNAAILEQLNSDVQLINQLGYYIVSGGGKRIRPM
IAVLAARAVGYEGNAHVTIAALIEFIHTATLLHDDVVDESDMRRGKATAN
AAFGNAASVLVGDFIYTRAFQMMTSLGSLKVLEVMSEAVNVIAEGEVLQL
MNVNDPDITEENYMRVIYSKTARLFEAAAQCSGILAGCTPEEEKGLQDYG
RYLGTAFQLIDDLLDYNADGEQLGKNVGDDLNEGKPTLPLLHAMHHGTPE
QAQMIRTAIEQGNGRHLLKPVLEAMNACGSLEWTRQRAEEEADKAIAALQ
VLPDTPWREALIGLAHIAVQRDR
>Z5044 kbl, 2-amino-3-ketobutyrate CoA ligase (glycine acetyltransferase)
MRGEFYQQLTNDLETARAEGLFKEERIITSAQQADITVADGSHVINFCAN
NYLGLANHPDLIAAAKAGMDSHGFGMASVRFICGTQDSHKELEQKLAAFL
GMEDAILYSSCFDANGGLFETLLGAEDAIISDALNHASIIDGVRLCKAKR
YRYANNDMQELEARLKEAREAGARHVLIATDGVFSMDGVIANLKGVCDLA
DKYDALVMVDDSHAVGFVGENGRGSHEYCDVMGRVDIITGTLGKALGGAS
GGYTAARKEVVEWLRQRSRPYLFSNSLAPAIVAASIKVLEMVEAGSELRD
RLWANARQFREQMSAAGFTLAGADHAIIPVMLGDAVVAQKFARELQKEGI
YVTGFFYPVVPKGQARIRTQMSAAHTPEQITRAVEAFTRIGKQLGVIA
>Z5058 kdtB, putative enzyme of LPS biosynthesis
MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEE
RVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEM
QLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENV
HQALMAKLA
>Z2329 ldhA, fermentative D-lactate dehydrogenase, NAD-dependent
MKLAVYSTKQYDKKYLQQVNESFGFELEFFDFLLTEKTAKTANGCEAVCI
FVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLKVVRVPAY
DPEAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTGFTMYGKTAGVI
GTGKIGVAMLRILKGFGMRLLAFDPYPSAAALELGVEYVDLPTLFSESDV
ISLHCPLTPENYHLLNEAAFDQMKNGVMIVNTSRGALIDSQAAIEALKNQ
KIGSLGMDVYENERDLFFEDKSNDVIQDDVFRRLSACHNVLFTGHQAFLT
AEALTSISQTTLQNLSNLEKGETCPNELV
>Z0773 lipA, lipoate synthesis, sulfur insertion?
MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIKLPADST
RIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPF
CDVAHGRPVAPDANEPVKLAQTIADMALRYVVITSVDRDDLRDGGAQHFA
DCITAIREKSPQIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPR
IYRQVRPGABYNWSLKLLERFKEAHPEIPTKSGLMVGLGETNEXIIEVMR
DLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPDEFDEMKAEALAMGFTHAA
CGPFVRSSYHADLQAKGMEVK
>Z0775 lipB, lipoate biosynthesis protein B
MHEFTDTRDDSTLDEIWLVEHYPVFTQGQAGKAEHILMPGDIPVIQSDRG
GQVTYHGPGQQVMYVLLNLKRRKLGVRELVTLLEQTVVNTLAELGIEAHP
RADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDLSPFLRINPCGYA
GMEMAKISQWKPEATTNNIAPRLLENILALLNNPDFEYITA
>Z5477 menA, 1,4-dihydroxy-2-naphthoate-->dimethylmenaquinone
MTEQQISRTQAWLESLRPKTLPLAFAAIIVGTALAWWQGHFDPLVALLAL
ITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGVITQQEMKRALI
ITVVLICLSGLALVAVACHTLADFVGFLILGGLSIIAAITYTVGNRPYGY
IGLGDISVLVFFGWLSVMGSWYLQAHTLIPALILPATACGLLATAVLNIN
NLRDINSDRENGKNTLVVRLGEVNARRYHACLLMGSLVCLALFNLFSLHS
LWGWLFLLAAPLLVKQARYVMREMDPVAMRPMLERTVKGALLTNLLFVVG
IFLSQWAA
>Z3522 menB, dihydroxynaphtoic acid synthetase
MIYPDEAMLYAPVEWHXCSEGFEDIRYEKSTDGIAKITINRPQVRNAFRP
LTVKEMIQALABARYDDNVGVIILTGAGDKAFCSGGDQKVRGDYGGYKDD
SGVHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAADNA
IFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGL
VNTVVPLADLEKETVRWCREMLQNSPMALRCLKAALNADCDGQAGLQELA
GNATMLFYMTEEGQEGRNAFNQKRQPDFSKFKRNP
>Z3521 menC, o-succinylbenzoyl-CoA synthase; conversion of chorismate to 2-o-succinylbenzoyl-CoA
MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGEISPLPG
FSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELADTLPQ
AANYRTAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLL
EAIPDLHLRLDANRAWTPLKGQQFAKYVNPDYRHRIAFLEEPCKTRDDSR
AFARETGIAIAWDESLREPDFAFVAEEGVRAVVIKPTLTGSLEKVREQVQ
AAHALGLTAVISSSIESSLGLTQLARIAAWLTPDTIPGLDTLDLMQAQQV
RRWPGSTLPVVEVDALERLL
>Z3524 menD, 2-oxoglutarate decarboxylase; SHCHC synthase
MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHH
THFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKL
ILLTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVS
TIDHALGTLHAGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWL
REAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALWAQTLGWPLIG
DVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGXXLTGKRLLQWQAS
CEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIP
RLAEQAMQAVIACRDAFGEAQLAHRISXYLPEQGQLFVGNSLVVRLIDAL
SQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLN
ALALLRQVSAPLVLIVVNNNGGQIFSLLPTPKSERERFYLMPQNVHFEHA
AAMFELKYHRPQNWQELETVLADAWRTPTTTVIEMVVNDTDGAQTLQQLL
AQVSHL
>Z3525 menF, isochorismate hydroxymutase 2, menaquinone biosynthesis
MDQAQRFLRQHPEHADLRIWGLNAFDPSQGNLLLPRLEWRRCGGKATLRL
TLFSESSLQHDAIKAREFIATLVSIKPLPGLHLTTTREQHWPDKTGWTQL
IELATKTIAEGELDKVVLARATDLHFASPVNAAAMMAASRRLNLNCYHFY
MAFDGENAFLGSSPERLWRRRDKALRTEALAGTVANHPDDKQAQQLGEWL
MADDKNQRENMLVVEDICQRLQADTQTLDVLPPQVLRLRKVQHLRRCIWT
SLNKADDVICLHQLQPTAAVAGLPRDLARQFIAHHEPFTREWYAGXAGYL
SLQQSEFCVSLRSAKISGNVVRLYAGAGIVRGSDPEQEWQEIDNKAAGLR
TLLQME
>Z5476 menG, menaquinone biosynthesis, unknown
MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFEDNGLLYD
LLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVD
DLEELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTG
IILSEDPLDIE
>Z4287 metK, methionine adenosyltransferase 1 (AdoMet synthetase); methyl and propylamine donor, corepressor of met genes
MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGM
VLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQS
PDINQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQA
EVRKNGTLPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQ
EAVMEEIIKPILPAEWLTSATKFFINPTGRFVIGGPMGDCGLTGRKIIVD
TYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVS
YAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLHP
IYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK
>Z0445 mhpA, 3-(3-hydroxyphenyl)propionate hydroxylase
MAIQHPDIQPAVNHSVQVAIAGAGPVGLMMANYLGQMGIDVLVVEKLDKL
IDYPRAIGIDDEALRTMQSVGLVDNVLPHTTPWHAMRFLTPKGRCFADIQ
PMTDEFGWPRRNAFIQPQVDAVMLEGVSRFPNVRCLFSRELEAFSQQDDE
VTLHLKTAEGLREIVKAQWLVACDGGASFVRRTLNVPFEGKTAPNQWIVV
DIANDPLSTPHIYLCCDPVRPYVSAALPHAVRRFEFMVMPGETEEQLREP
QNMRKLLSKVLPNPDNVELIRQRVYTHNARLAQRFRIDRVLLAGDAAHIM
PVWQGQGYNSGMRDAFNLAWKLALVIQGKARDALLDTYQQERRDHAKAMI
DLSVTAGNVLAPPKRWQGTLRDGVSWLLNYLPPVKRYFLEMRFKPMPQYY
GGALVREGEAKHSPVGKMFIQPKVTLENGDVTLLDNAIGANFAVIGWGCN
PLWGMSDEQIQQWRALSTRFIQVVPEVQIHTAQDNHDGVLRVGDTQGRLR
SWFAQHNASLVVMRPDRFVAATAIPQTLGKTLNKLASVMTLTRPDADVSV
EKVA
>Z1000 moaA, molybdopterin biosynthesis, protein A
MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNKGFLTVD
EIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTT
NGYRLERDVANWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDA
AFEAGFEKVKVNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGS
ELFRKHHISGQVLRDELLRRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIM
PYEKDFCATCNRLRVSSIGKLHLCLFGEGGVNLRDLLEDDTQQQALEARI
SAALREKKQTHFLHQNNTGITQNLSYIGG
>Z1001 moaB, molybdopterin biosynthesis, protein B
MSQVSTEFIPTRIAILTVSNRRGEEDDTSGHYLRDSAQEAGHHVVDKAIV
KENRYAIRAQVSAWIASDDVQVVLITGGTGLTEGDQAPEALLPLFDREVE
GFGEVFRMLSFEEIGTSTLQSRAVAGVANKTLIFAMPGSTKACRTAWENI
IAPQLDARTRPCNFHPHLKK
>Z1002 moaC, molybdopterin biosynthesis, protein C
MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHH
KGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIE
TLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGG
KSGDFKVEADD
>Z1003 moaD, molybdopterin biosynthesis
MIKVLFFAQVRELVGTDATEVAADFPTVEALRQHLAAQSDRWALALEDGK
LLAAVNQTLVSFDHPLTDGDEVAFFPPVTGG
>Z1004 moaE, molybdopterin converting factor, subunit 2
MAETKIVVGPQPFSVGEEYPWLAERDEDGAVVTFTGKVRNHNLGDSVKAL
TLEHYPGMTEKALAEIVDEARNRWPLGLVTVIHRIGELWPGDEIVFIGVT
SAHRSSAFEAGQFIMDYLKTRAPFWKREATPEGDRWVEARESDQQAAKRW
>Z5389 mobA, molybdopterin---> molybdopterin-guanine dinucleotide, protein Ar
MNLMTTITGVVLAGGKARRMGGVDKGLLDLNGKPLWQHVADALMTQLSHV
VVNANRHQEIYQAGGLKXIEDSLADYPGPLAGMLSVMQQEAGEWFLFCPC
DTPYIPHDLAARLNHQRKDAPVVWVHDGERDHPTIAMVNRAIEPLLLEYL
QAGERRVMAFMRLAGGHAVDFSDHKDAFVNVNTPEELARWQEKR
>Z5388 mobB, molybdopterin-guanine dinucleotide biosynthesis protein B
MIPLLAFAAWSGTGKTTLLKKLIPALCARGIRPGLIKHTHHDMDVDKPGK
DSYELRKAGAAQTIVASQQRWALMTETPDEEELDLQFLASRMDTSKLDLI
LVEGFKHEEIAKIVLFRDGAGHRPEELVIDRHVIAVASDVPLNLDVALLD
INDVEGLADFVVEWMQNQDG
>Z1962 modD, putative molybdenum transport protein
MIFLSQAQIDALLLEDIQGGDLTTRALNIGHQHGYIEFFLRQGGCVSGVS
VACKMLTTLGLTIDDAVSDGSQANAGQRLIRAQGNAAALHQGWKAIQNVL
EWSCGVSDYLDQMLALLRERYPDGNIACTRKAIPGTRLLASQAILAAGGL
IHRAGCAETILLFANHRHFLHDNQDWSGAINQLRRHAPEKKIVVEADTPK
EAIAALRAQPDVLQLDKFSPQQATEIAQIAPSLAPHCTLALTGGINLTTL
KNYLDCGIRLFITSAPYYAAPADIKVSLQPAASI
>Z1050 moeA, molybdopterin biosynthesis
MEFTTGLMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDVVSPLDV
PGFDNSAMDGYAVRLADITSGQPLPVAGKSFAGQPYHGEWPAGTCIRIMT
GAPVPEGCEAVVMQEQTEQTDNGVRFTAEVRSGQNIRRRGEDISAGAVVF
PAGTRLTTAXLPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQ
IYDTNRLAVHLMLEQLGCEVINLGIIRDDPHALRAAFIEADSQADVVISS
GGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGN
PVSATLTFYQLVQPLLAKLSGNTASGLPARQRVRTASRLKKTPGRLDFQR
GVLHRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGNVEVGEWVE
VEPFNALFGGL
>Z1049 moeB, molybdopterin biosynthesis
MAELSDQEMLRYNRQIILRGFDFDGQEALKDSRVLVVGLGGLGCAASQYL
ASAGVGNLTLLDFDSVSLSNLQRQTLHSDATVGQPKVESARDALTRINPH
IAITPVNALLDDAELAALIAEHNLVLDCTDNVAVRNQLNAGCFAAKVPLV
SGAAIRMEGQITVFTYQDGEPCYRCLSRLFSENALTCVEAGVMAPLIGVI
GSLQAMEAIKLLAGYGKPASGKIVMYDAMTCQFREMKLMRNPGCEVCGQ
>Z0009 mog, required for the efficient incorporation of molybdate into molybdoproteins
MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDE
QAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFG
EQMRQISLHFVPTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKDAE
GNVVVHGIFASVPYCIQLLEGPYVETAPEVVAAFRPKSARRDVSE
>Z0919 nadA, quinolinate synthetase, A protein
MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYT
DPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSP
EKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARA
DWVVTSSIAVELIDHLDSLGEKIIWAPDKHLGRYVQKKTGADILCWQGAC
IVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVDMADAVGSTSQLIAAA
KTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWM
AMNGLQAIAEALEQEGSNYEVHVDERLRERALVPLNRMLDFAATLRG
>Z3856 nadB, quinolinate synthetase, B protein
MNTLLEHSCDVLIIGSGAAGLSLALRLADQHQVIVLSKGPVTEGSTFYAQ
GGIAAVFDETDSIDSHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQ
GVLFDTHIQPNGEESYHLTREGGHSHRRILHAADATGREVETTLVSKALN
HPNIRVLERSNAVDLIISDKIGLPGTRRVVGAWVWNRNKEKVETCHAKAV
VLATGGASKVYQYTTNPDISSGDGIAMAWRAGCRVANLEFNQFHPTALYH
PQARNFLLTEALRGEGAYLKRPDGTRFMPDFDVRGELAPRDIVARAIDHE
MKRLGADCMFLDISHKPADFIRQHFPMIYEKLLGLGIDLTQEPVPIVPAA
HYTCGGVMVDDHGRTDVEGLYAIGEVSYTGLHGANRMASNSLLECLVYGW
SAAEDITRRMPYAHDISTLPPWDESRVENPDERVIIQHNWHELRLFMWDY
VGIVRTTKRLERALRRITMLQQEIDEYYAHFRVSNNLLELRNLVQVAELI
VRCAMMRKESRGLHFTLDYPELLTHSGPSILSPGNHYINR
>Z0119 nadC, quinolinate phosphoribosyltransferase
MPPRRYNPDTRRDELLERINLDIPGAVAQALREDLGGTVDANNDITAKLL
PENSRSHATVITRENGVFCGKRWVEEVFIQLAGDDVTIIWHVDDGDVINA
NQPLFELEGPSRVLLTGERTALNFVQTLSGVASKVRHYVELLEGTNTQLL
DTRKTLPGLRSALKYAVLCGGGANHRLGLSDAFLIKENHIIASGSVRQAV
EKASWLHPDAPVEVEVENLEELDEALKAGADIIMLDNFETEQMREAVKRT
NGKALLEVSGNVTDKTLREFAETGVDFISVGALTKHVQALDLSMRFR
>Z2770 nadE, NAD synthetase, prefers NH3 over glutamine
MTLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLVLGISGG
QDSTLAGKLCQMAINELRQETGNESLQFIAVRLPYGVQADEQDCQDAIAF
IQPDRVLTVNIKGAVLASEQALREACIELSDFVRGNEKARERMKAQYSIA
GMTSGVVVGTDHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALG
CPEHLYKKAPTADLEDDRPSLPDEVALGVTYDNIDDYLEGKNVPQQVART
IENWYLKTEHKRRPPITVFDDFWKK
>Z5991 nadR, probable nadAB transcriptional regulator
MRNTEGDMSSFDYLKTAIKQQGCTLQQVADASGMTKGYLSQLLNAKIKSP
SAQKLEALHRFLGLEFPRQKKTIGVVFGKFYPLHTGHIYLIQRACSQVDE
LHIIMGFDDTRDRALFEDSAMSQQPTVPDRLRWLLQTFKYQKNIRIHAFN
EEGMEPYPHGWDVWSNGIKKFMAEKGIQPDLIYTSEEADAPQYMEHLGIE
TVLVDPKRTFMSISGAQIRENPFRYWEYIPTEVKPFFVRTVAILGGESSG
KSTLVNKLANIFNTTSAWEYGRDYVFSHLGGDEIALQYSDYDKIALGHAQ
YIDFAVKYANKVAFIDTDFVTTQAFCKKYEGREHPFVQALIDEYRFDLVI
LLENNTPWVVDGLRSLGSSVDRKEFQNLLVEMLEENNIEFVRVEEEDYDS
RFLRCVELVREMMGEQR
>Z4721 pabA, p-aminobenzoate synthetase, component II
MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDALKPQKVVIS
PGPCTPDEAGISLDVIRHYAGRLPILGVCLGHQAMAQAFGGKVVRAAKVM
HGKTSPITHNGEGVFRGLANPLTVTRYHSLVVEPDSLPACFEVTAWSETR
EIMGIRHRQWDLEGVQFHPESILSEQGHQLLANFLHR
>Z2855 pabB, p-aminobenzoate synthetase, component I
MKTLSPAVITLPWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYSRFDIVV
ADPICTLTTLGKETVVSESEKRTTTTDDPLQVLQQVLDRADIRPTHNEDL
PFQGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRH
TVSLLSHNDVNARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRRV
QEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAPFSAFLRLEQG
AILSLSPERFILCDNSEIQTRPIKGTXPRLPXXQEDSKQAEKLANSAKDR
AENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHLVSTITAQLPE
QLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFC
GNMDTSITIRTLTAIXGQIYCSAGGGIVADSQEEAEYQETFDKVNKILRQ
LEK
>Z1735 pabC, 4-amino-4-deoxychorismate lyase
MFLINGYKQESLSVSDRATQFGDGCFTTARVIDGKVSLLSAHIQRLQDAC
QRLMISCDFWPQLEQEMKTLAAEQQNGVLKVVISRGSGGRGYSTLNSGPA
TRILSVTAYPAHYDRLRNEGITLALSPVRLGRNPHLAGIKHLNRLEQVLI
RSHLEQTNADEALVLDSEGGVTECCAANLFWRKGNVVYTPRLDQAGVNGI
MRQFCIRLLAQSSYQLVEVQASLEEALQADEMVICNALMPVMPVRACGXV
SFSSATLYEYLAPLCERPN
>Z0145 panB, 3-methyl-2-oxobutanoate hydroxymethyltransferase
MKPTTIASLQKCKQEKKRFATITAYDYSFAKLFAEEGLNVMLVGDSLGMT
VQGHESTLPVTVEDIAYHTTAVRRGAPNCLLLADLPFMAYATPEQAFENA
ATVMRAGANMVKIEGGEWLVETVKMLTERAVPVCGHLGLTPQSVNIFGGY
KVQGRGDEASDRLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVI
GIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAETGDIRAAVRQYMAE
VESGVYPGEEHSFH
>Z0144 panC, pantothenate synthetase
MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEAKARADV
VVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYP
NGTETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGE
KDFQQLALIRKMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKI
APGLYKVLSSIADKLQAGERDLDEIIAIAGQELNEKGFRADDIQIRDADT
LLEVSETSKRAVILVAAWLGDARLIDNKMVELA
>Z0142 panD, aspartate 1-decarboxylase
MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVT
NGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEART
WRPNVAYFEGDNEMKRTAKAIPVQVA
>Z4618 panF, sodium/pantothenate symporter
MTMQLEVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMGGIVL
AMTLTATYISASSFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKF
AILARRYNAVTLNDMLFARYQSRLLVWLASLSLLVAFVGAMTVQFIGGAR
LLETAAGIPYETGLLIFGISIALYTAFGGFRASVLNDTMQGLVMLIGTVV
LLIGVVHAAGGLSNAVQTLQTIDPQLVTPQGADDILSPAFMTSFWVLVCF
GVIGLPHTAVRCISYKDSKAVHRGIIIGTIVVAILMFGMHLAGALGRAVI
PDLTVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQLLQSSATII
KDLYLNIRPDQMQNETRLKRMSAVITLVLGALLLLAAWKPPEMIIWLNLL
AFGGLEAVFLWPLVLGLYWERANAKGALSAMIVGGVLYAVLATLNIQYLG
FHPIVPSLLLSLLAFLVGNRFGTSVPQATVLTTDK
>Z0061 pdxA, pyridoxine biosynthesis
MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLTDRAAML
GLPLTLRPYSPNSPAQPQTTGTLTLLPVALRESVTAGQLAIENGHYVVET
LARACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVV
MMLATEELRVALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAE
PRILVCGLNPHAGEGGHMGTEEIDTIIPVLDELRAQGMKLNGPLPADTLF
QPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTA
LELAGRGEADVGSFITALNLAIKMIVNTQ
>Z3582 pdxB, erythronate-4-phosphate dehydrogenase
MKILVDENMPYARDLFSRLGEVIAVPGRPIPVAQLADADALMVRSVTKVN
ESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVF
SSLLMLAERDGFSLHERTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRA
DCGDEGDFRSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPG
AILINACRGAVVDNTAXLTCLNEGQKLSVVLDVWEGEPELNVELLTKVDI
GTPHIAGYTLEGKARGTTQVFEAYSKFIGHEQHVALDTLLPAPEFGRITL
HGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPGEFDKLRKNYLERREWS
SLYVICDDASAASLLCKLGFNAVHHPAR
>Z2652 pdxH, pyridoxinephosphate oxidase
MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACEAKLADP
TAMVVATVDEHGQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQIENNPRVS
LLFPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGSWVSKQSSRI
SARGILESKFLELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHD
RFLYQRENDAWKIDRLAP
>Z3845 pdxJ, pyridoxine biosynthesis
MAELLLGVNIDHIXTLRNARGTAYPDPVQAAFIAEQAGADGITVHLREDR
RHITDRDVRILRQTLDTRMNLEMAVTEEMLAIAVETKPHFCCLVPEKRQE
VTTEGGLDVAGQRDKMRDACKRLADAGIQVSLFIDADEEQIKAAAEVGAP
FIEIHTGCYADAKTDAEQAQELARIAKAATFAASLGLKVNAGHGLTYHNV
KAIAAIPEMHELNIGHAIIGRAVMTGLKDAVAEMKRLMLEARG
>Z3684 pdxK, pyridoxal/pyridoxine/pyridoxamine kinase
MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVP
TVLLSNTPHYDTFYGGAIPDEWFSGYLRALQERDALRQLRAVTTGYMGTA
SQIKILAEWLTAXRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLL
PLAQGITPNIFELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVITSASGN
EENQEMLVVVVTADSVNVISHSRVKTDLKGTGDLFCAQLISGLLKGKALN
DAVHRAGLRVLEVMRYTQQHESDELILPPLAEA
>Z2648 pdxY, pyridoxal kinase 2 / pyridoxine kinase
MMKNILAIQSHVVYGHAGNSAAEFPMRRLGANVWPLNTVQFSNHTQYGKW
TGCVMPPSHLTEIVQGIAAIDKLHTCDAVLSGYLGSAEQGEHILGIVRQV
KAANPQAKYFCDPVMGHPEKGCIVAPGVAEFHVRHGLPASDIIAPNLVEL
EILCEHPVNNVEEAVLAARELIAQGPQIVLVKHLARAGYSRDRFEMLLVT
ADEAWHISRPLVDFGMRQPVGVGDVTSGLLLVKLLQGATLQEALEHVTAA
VYEIMVTTKAMQEYELQVVAAQDRIAKPEHYFSATKL
>Z1279 pncB, nicotinate phosphoribosyltransferase
MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGDDLLGIY
ADAIREQVQAMQHLRLQDDEYQWLSALPFFKADYLNWLREFRFNPEQVTV
SNDNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTL
ESKLVDFSALTAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQESWFVG
TSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLANSQRAALAAWLEEYPD
QLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYEK
LEIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQLSFGIGTRLTCDIPQVK
PLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPHIKKAS
>Z0920 pnuC, required for NMN transport
MDFFSVQNILVHIPIGAGGYDLSWIEAVGTIAGLLCIGLASLEKISNYFF
GLINVTLFGIIFFQIQLYASLLLQVFFFAANIYGWYAWSRQTSQNEAELK
IRWLPLPKALSWLAVCVVSIGLMTVFINPVFAFLTRVAVIIMQALGLQVA
MPELQPDAFPFWDSCMMVLSIVAMILMTRKYVENWLLWVIINVISVVIFA
LQGVYAMSLEYIILTFIALNGSRMWINSARERGSRALSH
>Z1105 poxB, pyruvate oxidase
MKQTVAAYIAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEWMSTRHE
EVAAFAAGAEAQLSGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAA
HIPSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVL
NRGVSVVVLPGDVALKPAPEGATTHWYHAPQPVVTPEEEELRKLAQLLRY
SSNIALMCGSGCAGAHKELVEFAGKIKAPIVHALRGKEHVEYDNPYDVGM
TGLIGFSSGFHTMMNADTLVLLGTQFPYRAFYPTDAKIIQIDINPASIGA
HSKVDMALVGDIKSTLRALLPLVEEKADRKFLDKALEDYRDARKGLDDLA
KPSEKAIHPQYLAQQISHFAADDAIFTCDVGTPTVWAARYLKMNGKRRLL
GSFNHGSMANAMPQALGAQATEPERQVVAMCGDGGFSMLMGDFLSVVQMK
LPVKIIVFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGITGIR
VEKASEIDEALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYM
LRAIISGRGDEVIELAKTNWLR
>Z2531 ribA, GTP cyclohydrolase II (EC 3.5.4.25)
MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHTPVLARV
HSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLN
KIRAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTN
NPKKVEILTEAGINIVERVPLIVGRNPNNEHYLDTKAEKMGHLLNK
>Z4399 ribB, 3,4 dihydroxy-2-butanone-4-phosphate synthase
MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMIFPAETM
TVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIE
AAEGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTR
GGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALV
TIEDLVAYRQAHERKAS
>Z0515 ribD, bifunctional pyrimidine deaminase/reductase in pathway of riboflavin synthesis
MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQRAGEPH
AEVHALRMAGEKAKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVAAM
QDPNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQ
LKLGASLDGRTAMASGESQWITSPQARRDVQRLRAQSHAILTSSATVLAD
DPALTVRWSELDVQTQALYPQHHLRQPVRIVIDSQNRVTPEHHIVQQPGE
TWFARTQEDSREWPETVRTLLIPEHKGHLDLVVLMMQLGKQQINSIWVEA
GPTLAGALLQAGLVDELIVYIAPKLLGSDARGLCTLPGLEKLADAPQFKF
KEIRHVGPDVCLHLVGA
>Z2688 ribE, riboflavin synthase, alpha chain
MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAHNGCCLT
VTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMS
GHIMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVG
EVTPTRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLA
ARENAMNQSGTEA
>Z0029 ribF, putative regulator
MKLIRGIHNLSQAPQEGCVLTIGNFDGVHRGHRALLQGLQEEGRKRNLPV
MVMLFEPQPLELFATDKAPARLTRLREKLRYLAECGVDYVLCVRFDRRFA
ALTAQNFISDLLVKHLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFD
ITSTQTFCEGGVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDE
LGRTIGFPTANVPLRRQVSPVKGVYAVEVLGLGEKPLPGVANIGTRPTVA
GIRQQLEVHLLDVAMDLYGRHIQVVLRKKIRNEQRFASLDELKAQIARDE
LTAREFFGLTKPA
>Z1079 rimK, ribosomal protein S6 modification protein
MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPAASSIHY
KGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDK
LRSMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEXTQGIG
VVLAETRQAAESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAA
IERRAKEGDFRSNLHRGGAASVASITPQEREIXIKAARTMALDVAGVDIL
RANRGPLVMEVNASPGLEGIEKTTGIDIAGKMIRWIERHATTEYCLKTGG
>Z4251 serA, D-3-phosphoglycerate dehydrogenase
MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKES
IRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIP
VFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEAR
GKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDL
LNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALC
DALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEA
QENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPLHGGRRLMHIHENRPGV
LTALNKIFAEQGVNIAAQYLQTSAQMGYVVIDIEADEDVAEKALQAMKAI
PGTIRARLLY
>Z1253 serC, 3-phosphoserine aminotransferase
MAQIFNFSSGPAMLPVEVLKQAQQELRDWNGLGTSVMEVSHRGKEFIQVA
EEAEKDFRDLLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAG
YWAASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMREWQLSDNAAYMHYCP
NETIDGIAIDETPDFGKDVVVAADFSSTILSRPIDVSRYGVIYAGAQKNI
GPAGLTIVIVREDLLGKANVACPSILDYSILNDNGSMFNTPPTFAWYLSG
LVFKWLKANGGVAEMDKINQQKAELLYGVIDNSDFYRNDVAKANRSRMNV
PFQLADSALDKLFLEESFAAGLHALKGHRVVGGMRASIYNAMPLEGVKAL
TDFMVEFERRHG
>Z0077 tbpA, thiamin-binding periplasmic protein
MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAFEADCNC
ELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSG
VAADAVNVPGGWNNDIFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQN
WRVIYQDPRTSTPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEA
YGLFLKGESDLVLSYTTSPAYHILEEKKDNYAAANFSEGHYLQVEVAART
AASKQPELAQKFLQFMVSPAFQNAIPTGNWMYPVANVTLPAGFEKLTKPA
TTLEFTPAEVAAQRQAWISEWQRAVSR
>Z5569 thiC, thiamin biosynthesis, pyrimidine moiety
MSATKLTRREQRAQAQHFIDTLEGTAFPNSKRIYITGTQPGVRVPMREIQ
LSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPW
IDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQL
HYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITA
EFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIE
EEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQAL
EKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTG
IVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGS
IQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEE
LEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKE
HLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWE
DQFNLALDPFTARAYHDETLPQESXKVAHXCSMCGPKFCSMKISQEVRDY
AAXQTIEMGIXDMSENFRAXGGEIYLRKEEA
>Z3267 thiD, phosphomethylpyrimidine kinase
MKRINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAQNTRGVQ
SVYRIEPDFVAAQLDSVFSDVRIDTTKIGMLAETDIVEAVAERLQRYQIQ
NVVLDTVMLAKSGDPLLSPSAVATLRSRLLPQVSLITPNLPEAAALLDAP
HARTEQEMLEQGRALLAMGCGAVLMKGGHLDDEQSPDWLFTREGEQRFTA
PRIMTKNTHGTGCTLSAALAALRPRHTNWADTVQEAKSWLSSALAQADTL
EVGHGIGPVHHFHAWW
>Z5568 thiE, thiamin biosynthesis, thiazole moiety
MYXPDFPPVPFRXXLYPVVDSVQWIERLLDAGVRTLQLRIKDRRDEEVEA
DVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLNAIRA
AGLRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLA
RHVERLSDYPTVAIGGISLARAPAVIATGVGSIAVVSAITQAADWRLATA
QLLEIAGVGDE
>Z5567 thiF, thiamin biosynthesis, thiazole moiety
MRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAALYLAGAGVGTLV
LADDDDVHLSNLQRQILFTTEDIDRPKSQVSHQRLTQLNPDIQLTALQQR
LTGEALKDAVAQADVVLDCTDNMATRQEINAACVALNTPLITASAVGFGG
QLMVLTPPWGQGCYRCLWPENQEPERNCRTAGVVGPVVGVMGTLQALEAI
KLLSGIETPAGELRLFDGKSSQWRSLALRRASGCPVCGGSNADPV
>Z5565 thiG, thiamin biosynthesis, thiazole moiety
MSSGRNISCRMATRSYFFRLLQGVEMLRIADKTFDSHLFTGTGKFASSQL
MVEAIRASGSQLVTLAMKRVDLRQHNDAILEPLIAAGVTLLPNTSGAKTA
EEAIFAAHLAREALGTNWLKLEIHPDARWLLPDPIETLKAAETLVQQGFV
VLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQGLETRAMLEIIIQQAT
VPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVNMAKAFRLAVE
AGLLAPQSGPGSRSYFAHATSPLTGFLEASV
>Z5564 thiH, thiamin biosynthesis, thiazole moiety
MKTFSDRWRQLDWDDIRLRINGKTAADVERALNASQLTRDDMMALLSPAA
SGYLEQLAQRAQRLTRQRFGNTVSFYVPLYLSNLCANDCTYCGFSMSNRI
KRKTLDEADIARESAAIREMGFEHLLLVTGEHQAKVGMDYFRRHLPALRE
QFSSLQMEVQPLAETEYAELKQLGLDGVMVYQETYHEATYARHHLKGKKQ
DFFWRLETPDRLGRAGIDKIGLGALIGLSDSWRVDCYMVAEHLLWLQQHY
WQSRYSVSFPRLRPCTGGIEPASIMDERQLVQTICAFRLLAPEIELSLST
RESPWFRDRVIPLAINNVSAFSKTQPGGYADNHPELEQFSPHDERRPEAV
AAALTAQGLQPVWKDWDSYLGRASQRL
>Z0519 thiL, thiamin-monophosphate kinase
MACGEFSLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAISTDTLV
AGNHFLPDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPDVDEAWL
ESFSDSLFDLLNYYDMQLIGGDTTRGPLSMTLGIHGFVPMGRALTRSGAK
PGDWIYVTGTPGDSAAGLAILQNRLQVADAKDADYLIKRHLRPSPRILQG
QALRDLANSAIDLSDGLISDLGHIVKASDCGARIDLALLPFSDALSRHVV
PEQALRWALSGGEDYELCFTVPELNRGALDVALGHLGVPFTCIGQMTADI
EGLCFIRDGEPVTLDWKGYDHFATP
>Z3268 thiM, hydoxyethylthiazole kinase
MQVDLLSSAQSAHTLHLFHQHSPLVHCMTNDVVQTFTANTLLALGASPAM
VIETEEASQFAAIASALLINVGTLTQPRAQAMRAAVEQAKSSQTPWTLDP
VAVGALDYRRHFCHELLSFKPAAIRGNASEIMALAGVANGGRGVDTTDAA
VNAIPAAQTLARETGAIVVVTGEVDYVTDGHRAVGIHGGDPLMTKVVGTG
CALSAVVAACCALPGDMLENVASACHWMKQAGERAVARSEGPGSFXPHFL
DALWQLTQEVQA
>Z5566 thiS, thiamin biosynthesis, probable sulfur donor
MQILFNDQPMQCAAGQTVHELLEQLVQRQAGAALAINQQIVPREQWTQHI
VQDGDQIXLFQVIAGG
>Z5639 ubiA, 4-hydroxybenzoate-octaprenyltransferase
MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILA
VFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALF
VVLVLIXFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAF
GWSIPMAFAAVSESVPLSCWLMFLANIXWAVAYDTQYAMVDRDDDVKIGI
KSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAGALF
VYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
>Z5365 ubiB, ferrisiderophore reductase; flavin reductase (NADPH:flavin oxidoreductase)
MTTLSCKVTSVEAITDTVYRVRIVPDAAFSFRAGQYLMVVMDERDKRPFS
MASTPDEKGFIELHIGASEINLYAKAVMDRILKDHQIVVDIPHGEAWLRD
DEERPMILIAGGTGFSYARSILLTALARNPNRDITIYWGGREEQHLYDLC
ELEALSLKHPGLQVVPVVEQPEAGWRGRTGTVLTAVLQDHGTLAEHDIYI
AGRFEMAKIARDLFCSERNAREDRLFGDAFAFI
>Z5638 ubiC, chorismate lyase
MRLLRFCCALDHLICFTSPVNTFLRYNAFTLCNGEFGMSHPALTQLRALR
YCKEIPALEPQLLDWLLLEDSMTKRFEQQGKTVSVTMIREGFVEQNEIPE
ELPLLPKESRYWLREILLCADGEPWLAGRTVVPVSTLSGPELALQKLGKT
PLGRYLFTSSTLTRDFIEIGRDAGLWGRRSRLRLSGKPLLLTELFLPASP
LY
>Z5355 ubiE, 2-octaprenyl-6-methoxy-1,4-benzoquinone-->2-octa prenyl-3-methyl-6-methoxy-1,4-benzoquinone
MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMSFGIHRL
WKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESM
LKMGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKD
KALRSMYRVLKPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVAN
DADSYRYLAESIRMHPDQDTLKAMMQDAGFESVDYYNLTAGVVALHRGYK
F
>Z3486 ubiG, 3-demethylubiquinone-9 3-methyltransferase and 2-octaprenyl-6-hydroxy phenol methylase
MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLSYIAE
RAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALE
SGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVK
PGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGW
VDQTSLKERHITGLHYNPITNTFKLGPGVDVNYMLHTQNK
>Z4244 ubiH, 2-octaprenyl-6-methoxyphenol--> 2-octaprenyl-6-methoxy-1, 4-benzoquinone
MSVIIVGGGMAGATLALAISRLSHGALPVHLIEATAPESHAHPGFDGRAI
ALAAGTCQQLARIGVWQSLADCATAITTVHVSDRGHAGFVTLAAEDYQLA
ALGQVVELHNVGQRLFALLRKAPGVTLHCPDRVANVARTQSHVEVTLEGG
ETLTGRVLVAADGTHSALATVCGVDWQQEPYEQLAVIANVATSVAHEGRA
FERFTQHGPLAMLPMSDGRCSLVWCHPLERREEVLSWSDEKFCRELQSAF
GWRLGKITHAGKRSAYPLALTHAARSITHRTVLVGNAAQTLHPIAGQGFN
LGMRDVMSLAETLTQAQERGEDMGDYGVLCRYQQRRQSDREATIGVTDSL
VHLFANRWTPLVVGRNIGLMTMELFTPARDVLAQRTXGWVAR
>Z3573 ubiX, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MKRLIVGISGASGAIYGVRLLQVLRDVTDIETHLVMSQAARQTLSLETDF
SLREVQALADVTHDARDIAASISSGSFQTLGMVILPCSIKTLSGIVHSYT
DGLLTRAADVVLKERRPLVLCVRETPLHLGHLRLMTQAAEIGAVIMPPVP
AFYHRPQSLDDVINQTVNRVLDQFAITLPEDLFARWQGA
>Z4243 visC, orf, hypothetical protein
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADAPPQLRV
SAINAASEKLLTRLGVWQDILSRRASCYHGMEVWDKDSFGHISFDDQSMG
YSHLGHIVENSVIHYALWNKAQQSSDITLLAPAELQQVAWGENETFLTLK
DGSMLTARLVIGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDA
VARQVFHGEGILAFLPLSDPHLCSIVWSLSPEEAQRMQQASEDEFNRALN
IAFDNRLGLCKVESARQVFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQ
GVNLGFMDAAELIAELKRLHRQGKDIGQYIYLRRYERSRKHSAALMLAGM
QGFRDLFSGTNPVKKLLRDIGLKLADTLPGVKPQLIRQAMGLNDLPEWLR
>Z0075 yabJ, putative ATP-binding component of a transport system
MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNLIAGFLT
PASGALTIDGVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGL
KLNAVQQEKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPI
LLLDEPFSALDPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRS
VVVADGRIAWQGMTNELLSGKASASALLGITG
>Z0113 yacE, putative DNA repair protein
MRYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGAPALHAI
ADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQI
QQATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTRE
HVEQILAAQATREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQF
VSQEKP
>Z0758 ybdU, orf, hypothetical protein
MHLLPELASHHAVSIPELLVSRDERQARQHVWLKRHPVPLVSFTVVAPGP
IKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAP
ARDLKLATIELEHXHPLGRLWDIDVLTPEGEILSRRDYSLPPRRCLLCEQ
SAAVCARGKTHQLTDLLNRMEALLNDVDACNVN
>Z0786 ybeN, orf, hypothetical protein
MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPPHRPQPE
ANSVQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDV
PLAFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWL
EDHLTHNPEDLHLQPAGKIYLAETPWFNISATIIRERLQNGESCDDLLPE
PVLTYINQQGLYR
>Z1666 ycdW, putative dehydrogenase
MRINFAQRFSGVSMDIIFYHPTFDTQWWIEALRKAIPQARVRAWKSGDND
SADYALAWHPPVEMLAGRDLKAVFALGAGVDSILSKLQAHPEMLKPSVPL
FRLEDTGMGEQMQEYAVSQVLHWFRRFDDYRIQQNSSHWQPLPEYHREDF
TIGILGAGVLGSKVAQSLQTWRFPLRCWSRTRKSWPGVQSFAGWEELSAF
LSQCRVLINLLPNTPETVGIINQQLLEKLPDGAYLLNLARGVHVVEDDLL
AALDSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHVAAITRPAEAVE
YISRTIAQLEKGERVCGQVDRARGY
>Z4075 ygcM, putative 6-pyruvoyl tetrahydrobiopterin synthase
MMSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTG
WIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVV
PLLSAVMVKETCTAGCIYRGE
>Z4129 ygdL, putative enzyme
MSVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALA
RTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINSEC
CVTVVDDFVTPDNVAQHMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLV
TTGGAGGQIDPTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLG
VDCVFSTEALVYPQSDGTVCAMKATAEGPKRMDCASGFGAATMVTATFGF
VAVSHALKKMMAKAARQG
>Z4249 ygfA, putative ligase
MIRQRRRALTPEQQQEMGQQAATRMMTYPPVVMAHTVAVFLSFDGELDTQ
PLIEQXWRAGKRVYLPVLHPFSAGNLLFLNYHPQSELVMNRLKIHEPKLD
VRDVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQHYKTQPVG
YAHDCQLVEKLPVEEWDIPLPAVVTPSKVWEW
>Z4300 yggW, putative oxidase
MVKLPPLXLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLDND
VAYAQGREVKTIFIGGGTPSLLSGSAMQTLLDGVRARLPLAADAEITMEA
NPGTVEADRFVDYQRAGVNRISIGVQSFSEEKLKRLGRIHGPQEAKRAAK
LASGLGLRSFNLDLMHGLPDQSLEEALGDLRQAIELNPPHLSWYQLTIEP
NTLFGSRPPVLPDDDALWDIFEQGHQLLTAAGYQQYETSAYAKPGYQCQH
NLNYWRFGDYIGIGCGAHGKVTFPDGRILRTTKTRHPRGFMQGRYLESQR
DVEAADKPFEFFMNRFRLLEPAPRVEFSAYTGLCEDVIRPQLDEAIAQGY
LTECADYWQITEHGKLFLNSLLELFLAE
>Z4411 ygiG, putative kinase
MMDIVFIEQLSVITTIGVYDWEQTIEQKLVFDIEMAWDNRKAAKSDNVAD
CLSYADIAETVVSHVEGARFALVERVAEEVAELLLARFNSPWVRIKLSKP
GAVARAANVGVIIERGNNLKENN
>Z4978 yiaE, putative dehydrogenase
MERSMKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFAEA
EGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTP
TVLTETVADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHK
TLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDT
LLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENAL
IAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYG
MAACAVDNLIDALQGKVEKNCVNPHVAD
>Z5207 yieE, orf, hypothetical protein
MERKMATHFARGILTEGHLISVRLPSQCHQEARNIPPHRQSRFLASRGLL
AELMFMLYGIGELPEIVTLPKGKPVFSDKNLPSFSISYAGNMVGVALTTE
GECGLDMELQRATRGFHSPHAPDNHTFSSNESLWVSKQNDPNEARAQLIT
LRRSVLKLTGDVLNDDPRDLQLLPIAGRLKCAHVNHVEALCDAEDVLVWS
VAVTPTIEKLSVWELDGKHGWKSLPDIHSRANNPTSRMMRFAQLSTMKAF
SPN
>Z5364 yigC, putative oxidoreductase
MDAMKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLRAGGPAL
LFENPKGYSMPVLCNLFGTPKRVAMGMGQEDVSALREVGKLLAFLKEPEP
PKGFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLNRIPIMTC
WPEDAAPLITWGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGA
LDYQEWCAAHPGERFPISVALGADPATILGAVTPVPDTLSEYAFAGLLRG
TKTEVVKCISNDLEVPASAEIVLEGYIEQGEMAPEGPYGDHTGYYNEVDS
FPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGVALNEVFVPILQKQFPE
IVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQFMYTKFVIV
CDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSK
MGLDATNKWPGETQREWGRPIKKDPDVVAHIDAIWDELAIFNNGKSA
>Z0811 yleB, orf, hypothetical protein
MTNQPTEIAIVGGGMVGGALALGLAQHGFTVTVIEHAEPAPFVADSQPDV
RISAISAASVSLLKGLGVWDAVQAMRCHPYRRLETWEWETAHVVFDAAEL
KLPLLGYMVENTVLQQALWQALEAHPKVTLRVPTSLIALHRDNDLQELEL
KGGEVIRAKLVIGADGANSQVRQMAGIGVHAWQYAQSCMLISVQCENDPG
DSTWQQFTPDGPRAFLPLFDNWASLVWYDSPARIRQLQNMNMAQLQVEIA
KHFPSRLGYVTPLAAGAFPLTRRHALQYVQPGLALVGDAAHTIHPLAGQG
VNLGYRDVDALIDVLVNARSYGEAWASYPVXKRYQMRRMADNFIMQSGMD
LFYAGFSNNLPPLRFVRNLGLMAAERAGVLKRQALKYALGL
>Z3472 yojL, orf, hypothetical protein
MEISFTRVALLAAALFFVGCDQKPQPAKTHATEVTVLEGKTMGTFWRASI
PGIDAKRSAELKEKIQTQLDADDQLLSTYKKDSALMRFNDSQSLSPWPVS
EAMADIVTTSLRIGAKTDGAMDITVGPLVNLWGFGPEQQPVQIPSQEQID
AMKAKTGLQHLTVINQSHQQYLQKDLPDLYVDLSTVGEGYAADHLARLME
QEGISRYLVSVGGALNSRGMNGEGLPWRVAIQKPTDKENAVQAVVDINGH
GISTSGSYRNYYELDGKRLSHVIDPQTGRPIEHNLVSVTVIAPTALEADA
WDTGLMVLGPEKAKEVVRREGLAVYMITKEGDSFKTWMSPQFKSFLVSEK
N