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# Streptococcus pyogenes phage 6180.4

>M28_Spy1682 para-aminobenzoate synthetase component I
MGMHRKTIIDFKELGQRYLFDEPLVELVAKSLDQVGPVIENVQHYQQLGY
YVVGYLSYEAAAFFDNALQTHNDRLGNEYLAYFTVHKTCQKKDLPLDYDG
ITIPNQWVSATQKEAYQKAIETIHREMQQGNTYQVNYTLQLTQELNAADS
LAIYNKLVVEQAAGYNAYIAHDDFAVISASPELFFKQEGNRLTTRPMKGT
TKRGVNSWLDQQEHDWLQADGKNRSENMMIVDLLRNDMGKICQTGSVCVD
RLCEVERYSTVWQMTSTIVGDVKADCDLIDILTALFPCGSITGAPKVSTM
AIITSLEPKPRGIYCGSIGICLPDGRRFFNVPIRTIQLSHNQATYGVGGG
ITWQSKWEDEYEEVHQKTAFLYRHKQIFDLKTTAKVKHKKIAFLEQHLNR
LKEAATYFAYPYDEKALQKQLSTYLENKDNAAYRLMIRLSKDGKISLSDQ
PLEPLSADFLTAQLSLQKKDVTASPFTYFKTSYRPHIEQKSYEQLFYNQA
GQLLETSIGNLFVQLGRTLYTPPVVVGILPGLFRQELLATGQAQEKEVTL
ADLKEASAIFGGNAVRGLYPLNLKLTHLDALLAKSQA
>M28_Spy1067 nicotinamide mononucleotide transporter
MNRGMAYLNYFTKTEWALWLSSVLAILISALLFGKQAPLALIASLIGVTS
LIFSAKANPIGQGLVIIFSIIYAYLSLRNSYYGELMTYLFMTLPMTIFSL
FTWLNHPFEGKKSQVTISRLTPTDRRCLFVFTILVTLIFYGILASIQTAY
LLVSTLSIATSFSAVYLSYKRSPYFALAYGLNDLVLILLWMHAAQTDASQ
YAVVICFATFLINDSYTFYSWLMLQRYQEKKVKKG
>M28_Spy0397 dephospho-CoA kinase
MSSLWTGYCQIKSWRKGDAHLSKMPEKKTMIIGITGGIASGKSTVVKVIR
KAGYQVIDADQVVHDLQEKGGRLYEALREAFGNQILKADGELDRTKLSEM
LFSNPDNMATSSAIQNQIIKEELAAKRDHLAQSQAIFFMDIPILMELGYQ
DWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQLPIEEKKPYASL
VIDNSGDIAALIKQVQSALLSLANPR
>M28_Spy1398 NH(3)-dependent NAD(+) synthetase
MITFVKILMERVNDMTLQEEIIRQLGVKASIDPQEEIRKTVDFLKAYLRK
HSFLKTYVLGISGGQDSTLAGKLAQMAIAELREETSDQAYQFIAVRLPYG
VQADEADAQKALAFIAPDQTLTINIKAAVDGQVEALQAAGVEISDFNKGN
IKARQRMISQYAIAGQMAGAVIGTDHAAENITGFFTKFGDGGADILPLFR
LNKRQGKALLKVLGADAALYEKVPTADLEDQKPGLADEVALGVTYQDIDD
YLEGKLISKAAQATIEKWWHKGQHKRHLPITIFDDFWK
>M28_Spy0895 pyridoxine kinase
MKRIIVANDLVGVGKVALSASIPLMASCLLEQVLLPTCLLSSHTGGGQSP
VKHTTSSILDVFLTDWDNKRIKFDGIFIGYFTTTRDGQKLLEWLSRKQLP
LILDPIMADNGKLYQGFSQKHIEIMIKLTQKAELVLPNISEACLLTQTAY
LAKNYDEEDIRQVARKLAKLGPKQVVISGISFEEGSIGFAYYQSDSDQLT
FHFGKQFPYHFYGTGDIASAIITAGFYYQLPLTQILDLVVSFLEKVLQNT
LTLKRDLILGVAYESHLNYLTKSFKKLLEEKNVISKIS
>M28_Spy0871 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MTKAVLTSISQLALKALLYEVSLSPKPGLVDRFDNGAHDDMSFMTFIDSM
IALSPFFQAYIETGFAYAKEEPLLLFNRLRQLGQKAEETMFCATQGINTH
KGLNFSMALLLGATGAYLARTPHLMTDLGCFSKEDTLAICRLVKPMTAHL
IQTDLGHLNTKKEFTYGEQLFVTYGIKGPRGEASEGFTTLTDHALPYFRQ
MISQNDPETSQLRLLVYLMSIVEDGNLIHRGGIEAWKGVKADMRLLLQQD
LSTTDLRLALSSYNQCLINQHLSPGGAADLLALTFYFAFLEKLL
>M28_Spy0906 lipoate-protein ligase A
MKGRIVITIRDLASLPIFVYGDGNKKVPGALSPFVWTEVFLKTINQEPNQ
LILHIWPMTRTVILGMLDRQLPYFELAKTEIGNNGYVPVTRNIGGLAVVA
DDGILNFSLVIPDHFSESISISNAYLIMVDVIRESFSDYYQRIEYHEIKN
SYCPGNFDLSIAGRKFAGIAQRRIKKGIVVSIYLSVCGDQAARGQLIKDF
YEAGTQGEVTKVNYPQIDPECMATLSELLETPFTVAEVLERLRLTLRQLG
FSLTEKSPDQALLTNFDAVYERMQLEVVRKEGK
>M28_Spy0256 hydrolase
MTYEDYLPYSRTELLAKIAEQMSPKRFKHVLGVEKAALSLAECYGCNPDK
AGLAALLHDYAKECPDQVFLDLIDKYQLSPELAKWNNNVWHGMVGIYKIQ
EDLGLKDKDILRAIEIHTVGAAEMTLLDKVLYVADYIEEGRIFPLVDDAR
KIAKLDLNQAVAYETVNTVAYLASKAQPIFPQTLDTYNAFCSYLKEY
>M28_Spy0219 thiamin pyrophosphokinase
MSKVALFAGGDLSYISRDFDYFVGIDRGSLFLLENGLPLNMAVGDFDSVS
QKAFTDIKEKAELFITAHPEKNDTDTELALKEVFARFPEAEVTIFGAFGG
RMDHLLSNIFLPSDPGIAPFMAQIALRDQQNMITYRPAGQHLIHQEEGMT
YVAFMAEGEADLTITGAKFELTQDNFFKKKIYSSNAFIHQPITVSLPSGY
LIIIQSKDWS
>M28_Spy1205 phosphopantetheine adenylyltransferase
MLTKIGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKKSYFKLE
VRKAMLTQALADFTNVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEY
EENLEYFNHLLAPNIETVYLISRNKWQALSSSRVRELIHFQSSLEGLVPQ
SVIAQVEKMNEKT
>M28_Spy0868 hypothetical membrane associated protein
MTYSFIDILQVTLVSLFLVLTCLTGIMGLMMLSGKLLSQEKKTLSQQASS
IPQEQEADKLSGEALETLLAKDELARIAVMTSLAYASQEESGKRFEVIAV
ERKS
>M28_Spy0640 apbA, 2-dehydropantoate 2-reductase
MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEDHINAIKENGLVVTGDV
EETVKLPIMKPTEATQEADLIILFTKAMQLPQMLQDIKGIIGKETKVLCL
LNGLGHEDVIRQYIPEHNILMGVTVWTAGLEGPGRAHLQGVGALNLQSMD
PNNQDAGHQVADLLNKANLNATYDENVVPNIWRKACVNGTMNSTCALLDC
TIGELFASEDGLKMVKEIIHEFVIVGQAEGVELNEEEITQYVMDTSVKAA
HHYPSMHQDLVQNHRLTEIDFINGAVNTKGEKLGINTPYCRMITELVHAK
EAVLNIQ
>M28_Spy0834 apbE, thiamine biosynthesis lipoprotein
MFVTQQLKLMGTVIDIQIESDKACQQLSRVIDLLYTYKNRFSANDSNSEL
MAINQAAGVKPLSVHSDLFNLIQIGKAHSLSTPSNLNIAIGPLVQAWRIG
FEDARVPSHNLISQQLALTDPRQVLIDDKKQTVFLQQVGMALDLGALAKG
YITDKIMAYLIEDGIDSALINLGGNVRVHGPNPKSPDKTFRIGIQKPDAK
RGQHLGVIKVNNHSVVTSGIYERQFTAKGKQYHHILDRQTGYPIETDMLS
LTIMAPSSFYCDIWATRLFGLDSSMIITLLNTFDNIEGLLVTRKHHVLMS
NGLRHYFQPYYH
>M28_Spy0693 bcaT, branched-chain amino acid aminotransferase
MKKSYNRKKQKRGTMMTIAIDWDNLGFEYHKLPFRYISYYKNGQWDKGQL
TEDATLHISESAPALHYGQQAFEGLKAYRTKDGSIQLFRPDRNAVRLQAT
ADRLLMPQVSTEQFIDAAKQVVKANEDFVPPYGTGATLYLRPLLIGVGDI
IGVKPAEEYIFTIFAMPVGNYFKGGLAPTNFIVSEAFDRAAPYGTGAAKV
GGNYAGSLLPGKAAKSAGFSDVIYLDPATHTKIEEVGAANFFGITANNEF
VTPLSPSILPSITKYSLLQLAEERLGMTVIEGDVPINELDKFVEAGACGT
AAVISPIGGIQYKDNLHVFYSETEVGPVTRRLYDELVGIQFGDIEAPEGW
IVKVD
>M28_Spy1102 birA, biotin operon repressor
MKTSEKIYQLLSQTDDFVSGEYLADQLSISRTSVWKSIKSLENQGIQIDS
LKHKGYRMVQGDILLPKTISQGLGMPVTYTPHSQSTQLDAKQGIEAHNSA
PRLYLAPSQEAAKGRLDRQFFSASTGGIYMSMYLKPNVPYADMPPYTMMV
ASSIVKAISRLTGIDTEIKWVNDIYLGNHKVAGILTEAITSVETGLITDV
IIGVGLNFFVTDFPEAIAQKAGSLFTEKPTITRNDLIIDIWKLFLSIPVK
DHVKVYKEKSLVLNKQVTFTENSQEKRAIAIDLTDQGHLIVQFENGDFQT
LRSGEISLSSWEN
>M28_Spy0881 citX, apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MVIRLLLLLNTVMVASWMWFTMCKDTYFSGEAIQLSDMLRAREERALRQL
HLLKEYPEGSLLSVTMNIPGPIKTSPKLLEVFDIVIKAIQTALADDKICY
QLRLLPTTGYEYYLITSLPSRDLKLKMIALETELPIGRLMDLDVLVLQND
LPHSISRTVLGGSPRQCFICSKEAKVCGRLRKHSVEEMQTAISKLLHSFF
NKDNQSSSSDKTG
>M28_Spy0917 coaA, pantothenate kinase
MSNEFINFEKISRESWKTLHQKAKALLTQEELKSITSLNDNISINDVIDI
YLPLINLIQVYKIAQENLSFSKSLFLKKDIQLRPFIIGISGSVAVGKSTT
SRLLQLLLSRTHPNSQVELVTTDGFLYPNQFLIEQGLLNRKGFPESYNME
LLLDFLDSIKNGQTAFAPVYSHDIYDIIPNQKQSFNNPDFLIVEGINVFQ
NQQNNRLYMSDYFDFSIYIDADSSHIETWYIERFLSILKLAKRDPHNYYA
QYAQLPRSEAIAFARNVWKTVNLENLEKFIEPTRNRAELILHKSADHKID
EIYLKK
>M28_Spy0863 ddh, D-lactate dehydrogenase
MMKLKLYNVRGEEAVLAKKWADDNGIEISLTESPLTPETVKEAEGFDGIA
NAQIGPLDDAIYPLLREMGIKQIAQRSAGVDMYNLDLATENDIIITNVPS
YSPESIAEFTVTIALNLIRHVELIRENVKKQNFTWGLPIRGRVLGDMTVA
IIGTGRIGLATAKIFKGFGCKVVGYDIYQSDAAKAVLDYKESVEEAIKDA
DFVSLHMPPTAENTHLFNADLFKSFKKGAILMNMARGALIETQDLLDALD
AGLLSGAGIDTYEFEGPYIPKNFEGQEITDSLFKALINHPKVIYTPHAAY
YTDEAVKNLVEGALNATVEIIKTGTTTTRVN
>M28_Spy0908 dfp, phosphopantothenoylcysteine decarboxylase
MTKHITLAVSGSISAYKAADLTSQLTKIGYDVHIIMTQAATQFITPLTLQ
VLSKNAIHLDVMDEHDPKVINHIELAKRTDLFIVAPASANTIAHLAYGFA
DNIVTSVALALPATTPKLIAPAMNTKMYQNPITQENIKRLSTIGFTEIPP
KSSLLACGDKGPGALADIDVILATIDTIWKL
>M28_Spy0907 dpfB, phosphopantothenate--cysteine ligase
MTMKLIITSGGTTEPIDAVRGITNHSTGQLGKLITERFLQYHHDVTLVTT
KTATKPLPNKLLRIIEVETVNDLMAALKDQVPHHDILIHSMAVSDYTPVY
MTDLEQVSQADNLNCFLCEHNSEPKISSASDYQVLFLKKTPKVISYVKQW
NPNIKLVGFKLLVNVPQEELIKVARASLAKNHADYILANDLVDIQTGMHK
ALLISNNEVASADTKEAIADLLYERMTKHD
>M28_Spy0669 dyr, dihydrofolate reductase
MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAVLMGRVTF
EGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYII
GGNKVLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARD
AKNPYDFTVTALKHK
>M28_Spy0313 fhuA, ferrichrome transport ATP-binding protein
MTTISAEDLTIAYEQRTIIDKLSFYIPEGKITTIIGANGCGKSSLLKALT
RLLPPKQGVVYLNGQNIATLETKEVAKKLALLPQVQEATNGITVYELVSY
GRFPHQSYFGNLSPADKKAIHWAMQATNVMAYADQPVDALSGGQRQRVWL
AMALAQGTDTIFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIVMVLHDL
NLSARYSDHLIAMKHGKIHYTGTIADVMTSPIIQDIFQIKPVLVDDPIHN
CPIVLTYQLQ
>M28_Spy1516 fhuC, ferrichrome transport ATP-binding protein
MSKNSSHIQVQNLSFAYEEKLVLDDLTFSIPKGKITTIMGANGSGKSTLL
QLLTKNLPLKQGQVWLEQEELATISLKAFAKKVAVVHQYHQVVEGLLVGE
LVAMARLARRSFFKTTTKEDEERLAWALEVTALSDYVYRDLQHLSGGEQQ
RVWIAMALAQDTDIIFLDEPTTYLDIKYQLDILKLITKINQELGLTIVLV
LHDINQALSLSDHLIGLKDGRLYAQGQPRDLLDQQFIRDVFGVELPFVER
NGQQFVLTSLVNETNDIRTQRRDRNKNR
>M28_Spy0797 folC.1, folylpolyglutamate synthase
MVRIIKKKGTTLGYLLSLFFIYGILKIDVRYEMTYEETLEWIHDHLVFGI
KPGLKRMLWVLGQLGNPQKNVKGVHIVGTNGKGSTVNHLQHIFTTAGYEV
GTFTSPYIMDFKERISINGRMISEKDLVIAANRIRPLTERLVQETDFGEV
TEFEVITLIMFLYFGDMHPVDIAIIEAGLGGLYDSTNVFQAMVVVCPSIG
LDHQAILGETYADIAAQKAGVLEGGETLVFAVENPSAREVFLTKAEQVGA
SIWEWQEQFQMAENASGYRFTSPLGVISDIHIAMPGHHQVSNAALAIMTC
LTLKDRYPRLTSDHIREGLANSLWLGRTELLAPNLMIDGAHNNESVAALV
AVLKNNYNDKKLHILFGAIDTKPIADMLVALEQIGDLQVTGFHYPNAYPL
EKYPERFGRVADFKDFLALRKHAKADDFFVITGSLYFISEIRQYWKKHIE
KNVLLTH
>M28_Spy0608 folC.2, folylpolyglutamate synthase
MLEGQEIVMTTYDSISWIHTFKANGRKTDLARMAWLLEALGRPQDKFPAI
HVVGTNGKGSVTAYLQHILSTSGYQVGTFTSPFIISFHDRICLNGQPISD
LELAQCVSVIRPILTKMSLETNWDRPTEFELVTLIMFCYFANLKPVDIAI
IEAGIGGKTDATNVFHALAVVCPSISFDHQERLGYSLAEIAHQKAEVIKA
KEPVIIGQLEQEASQVFQQVTQKAGSRLYQLGKDFLLNPSEKTFSFQHDN
LNLTKLRLKLLGQHQKANACLAIMTAQLLRKSFPKISPKTIQKGIEATTW
PGRSEFIQPNLLLDGAHNPDSIAKLKSLLQEEFPKRPIHILFAGLKRKPL
ADLLAQLDTFEVSVTTFDFPEANLLEDYPDKYPQVKDYRDWLQGSVTSDE
LFVVTGSLYFISEVRQYCLSNANIFKNIFP
>M28_Spy1173 folD, methylenetetrahydrofolate dehydrogenase (NADP+)
MSMTELIDGKALAQKMQQELAAKVNNLKQKKGIVPGLAVILVGDDPASQV
YVRNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQL
PLPNHINDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMEL
LREYNVNLEGKHAVIIGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEV
CRCADVLIVAIGQGHFITKQYIKDGAIVIDVGMNRDDNGKLIGDVAFDEV
AEVAAKITPVPGGVGPMTIAMLLEQTYQSALRSTHK
>M28_Spy0798 folE, GTP cyclohydrolase I
MKRKRKKLMKRERLMSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVA
KMYAEMFLGLGKDPKEEFTAVFKEQHEDVVIVKDISFYSICEHHLVPFYG
KAHIAYLPSDGRVTGLSKLARAVEVASKRPQLQERLTSQIADALVEALNP
KGTLVMVEAEHMCMTMRGIKKPGSKTITTTARGLYKESRAERQEVISLMT
KD
>M28_Spy0801 folK, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase
MTIVYLSLGTNMGDRAAYLQKALEALADLPQTRLLAQSSIYETTAWGKTG
QADFLNMACQLDTQLTAADFLKETQAIEQSLGRVRHEKWGSRTIDIDILL
FGEEFYDTKELKVPHPYMTERAFVLIPLLELQPDLKLPPNHKFLRDYLAA
LDQSDITLFSAQQTEF
>M28_Spy0799 folP, dihydropteroate synthase
MKIGKFVIEGNAAIMGILNVTPDSFSDGGSYTTVQKALDHVEQMIADGAK
IIDVGGESTRPGCQFVSATDEIDRVVPVIKAIKENYDILISIDTYKTETA
RAALEAGADILNDVWAGLYDGQMFALAAEYDAPIILMHNQDEEVYQEVTQ
DVCDFLGNRAQAALDAGVPKNNIWVDPGFGFAKSVQQNTELLKGLDRVCH
LGYPVLFGISRKRVVDALLGGNTKAKERDGATAALSAYALGKGCQIVRVH
DVKANQDIVAVLSQLM
>M28_Spy0800 folQ, dihydroneopterin aldolase
MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLSDQLTDT
VHYGMVFDSVRQLVEGEKFILIERLAGAICEQLFNEFPPIEAIKVAIKKE
NPPIAGHYKAVGIELERQR
>M28_Spy1170 fps, dimethylallyltransferase
MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPLILLEMI
EGFGVSLQNAHFDLAAALEMIHTGSLIHDDLPAMDNDDYRRGRLTNHKQF
GEATAILAGDSLFLDPFGLIAQAELNSEVKVALIQELSLASGTFGMVGGQ
MLDMKGENQALSLPQLSLIHLNKTGKLLTFPFKAAALVTEQAITVRQQLE
QAGMLIGHAFQIRDDILDVTASFEDLGKTPKKDLFAEKATYPSLLGLEAS
YQLLTESLDQALTIFQTLESDVGFKPQIITKLIEGLRLNA
>M28_Spy0744 hemN, coproporphyrinogen oxidase
MSARKIFFQAMKNQGKWLIHRNILSSKWYNKTMSKKPTSAYVHIPFCTQI
CYYCDFSKVFIQNQPVDAYLKALIQEFDSYGIRDLKTLYIGGGTPTAITA
KQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPEKIAVLQRSAVNRISLG
VQTFNNKQLKQIGRSHNEEQIYSTIANLKTAGFHNISIDLIYALPGQTLD
QVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEM
FEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGY
LNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTG
VSIQRFQEKFGVSFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDS
VAERFILD
>M28_Spy0900 lplA, lipoate-protein ligase A
MYLIEPIRNGKRITDGAVALAMQVYVQENLFLDDDILFPYYCDPKVEIGK
FQNAVVETNQEYLKEHHIPVVRRDTGGGAVYVDSGAVNICYLINDNGIFG
DFKRTYQPAIEALHHLGATEVEMSGRNDLVIDGKKVSGAAMTIANGRVYG
GYSLLLDVDFEAMEKALKPNRKKIESKGIRSVRSRVGNIREHLAPQYQGI
TIEEFKDLMVCQLLQIETISQAKRYDLTEKDWQQIDALTERKYHNWEWNY
GNAPQYRYHRDGRFTGGTVDIHLDIKKGYIAACRIYGDFFGKADIAELEG
HLIGTRMEKEDVLATLNAIDLAPYLGAITAEELGDLIFS
>M28_Spy0737 lplB, lipoate-protein ligase A
MKYIVNKSHNPAFNIALEAYAFRELVEEDELFILWINEPAIIIGKHQNTI
QEINKEYIDEHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTAEGAFDFKT
FSQPVIATLADLGVTANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLL
FDVDMTVLGDALKVSKDKIESKGVKSVRARVTNILNELPEKITVEEFSDK
ILTKMKETYPDMTEYVLSEDELAKIEQSAKEQFGSWDWTYGKAPEYTIER
NVRYPAGKISTFANVENSIIKNLKIYGDFFGIKDVQDIENLLIGCKYEYR
DVFECLKTIDTTQYFSRMTVEEVAKAIVS
>M28_Spy1100 metK2, S-adenosylmethionine synthetase
MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAETCVYTG
SVHVFGEISTKAYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQ
SGDIAQGVNEALESREGDTDDLSHIGAGDQGLMFGFAINETPELMPLPIS
LSHQLVRRLAELRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQ
HDPEATNDQIRQDVIEKVIKAVIPADYLDDDTKFFINPTGRFVIGGPQGD
SGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNLVAA
GLATKAEVQLAYAIGVAQPVSVRVDTFGTSTVPEAVLEAAVRQVFDLRPA
GIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWERLNKVDALVEAVKTVL
>M28_Spy0933 mreA, riboflavin kinase
MEIEYIKDYRDINQEDDTVLVLGYFDGLHRGHKALFEKAREVANKEGLKV
VVFTFTESPKLAFSRFSPELLLHITYPKKRYEKFADYGVNKLYLVDFTSK
FSKVSSDHFITHYIKNLKAKHIVVGFDYKFGHNCTDSDYLTRNFEGQVYT
IKEIKEDHRKISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGR
TIGFPTANLAPIDNTYLPADGVYVTNVIVANKIYRSMTSLGKNVTFGGKE
LRLEVNIFDFDEEIYGEIIEIVWLDKIRDMEKFEGIEDLTDRLEYDKRTA
LNWKKDSKLS
>M28_Spy0168 nadC, carboxylating nicotinate-nucleotide pyrophosphorylase
MILKIEDLVMSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQ
AKVSLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLASGDLV
LEIIGSVRSLLTCERVALNFLQHLSGIASMTAAYVEALGDDRIKVFDTRK
TTPNLRLFEKYAVRVGGGYNHRFNLSDAIMLKDNHIAAVGSVQKAIAQAR
AYAPFVKMVEVEVESLAAAEEAAAAGVDIIMLDNMSLEQIEQAITLIAGR
SRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAKSLDFSMKGLTYLDV
>M28_Spy0255 nadD, nicotinate-nucleotide adenylyltransferase
MALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVADQVRQQ
LGLDQVLLMPECKPPHVDAKETIDEKHRLRMLELAIEDVEGLAIETCELE
RQGISYTYDTMLYLTEQHPDVDFYFIIGADMVDYLPKWHRIDELVKLVQF
VGVQRPKYKAGTSYPVIWVDLPLMDISSSMIRDFIKKGRQPNYLLPKRVL
DYITQEGLYQ
>M28_Spy1399 nadE, nicotinate phosphoribosyltransferase
MYKDDSLTLHTDLYQINMMQVYFEQGIHNRHAVFEVYFRKEPFNNGYAVF
AGLQRMVEYLEQFQFSETDLAYLEELGYPGNFLTYLKELRLELTIRSAKE
GDLVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIED
EPLLEFGTRRAQELDAAIWGTRAAMIGGADATSNVRAGKRFDIPVSGTHA
HALVQAYGNDYDAFMAYAKTHKDCVFLVDTYDTLKVGVPTAIRVAKEMGD
KINFLGVRLDSGDLAYLSKTVRQQLDDAGFTEAKIYASNDLDENTILNLK
MQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIEQEDGSMRDTIKLSNNA
EKVSTPGKKQVWRITSREKGKSEGDYITFTDINVNELTEIEMFHPTYTYI
KKTVRNFDAIPLLVDIFVKGELVYQLPTLSEIKTYAKKEFDKLWDEYKRV
LNPQDYPVDLARDVWQNKMTLIDNIRKDTHGKSE
>M28_Spy1605 thiD, phosphomethylpyrimidine kinase
MKTDYIVTISGNDILSGGGLYADLATYIRYDLQAFVAVTCLTTRSEEGFS
LFPVAKEIFRDQLNSFTNAPISAIKIGLLPNAEMCEIVLDFIKGHLGIPV
VLDPVLACKEIDDVKIVPLRQEILQLLPYVTVVTPNLVEAQLLSQKEIVS
LKDMQEAAKYFYQLGAKQVVIKGGNRFSQKKAIDLFYDGKEIVTLECPVL
EKNNIGAGCTFASSIASQLVKKKTPLEAVKNSKELVYQAILQSDRYGVKQ
SYAK
>M28_Spy0611 thiI, thiamine biosynthesis protein
MDYSEIMVRHGELSTKGKNRMRFINKLKNNIQDVLAPFPAIAVRSDRDRT
HVSLNGTDYQPIVEALKLVFGVQALSPVYKLEKSVPLLVTAVQDIMTSLY
RDGLTFKIATKRSDHAFELDSRELNSLLGGAVFEVLPNIQAQMKHPDVTL
KVEIRDEAAYISYEEIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKR
GLDIEVVHFASPPYTSPGALAKAQDLTRRLTRFGGNIQFIEVPFTEIQEE
IKNKAPEAYLMTLTRRFMMRITDAIREQRKGLVIVNGESLGQVASQTLES
MQAINAVTSTPIIRPVVTMDKLEIIEMAQAIDTFDISIQPFEDCCTIFAP
DRPKTNPKLGNAEKYEERFDIDGLVQRAVSGIVVTEITPEIVNDEVENLI
DALL
>M28_Spy1683 trpG, anthranilate synthase component II
MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKANALVLSPG
PGWPKEANQMPKLIQDFYQTKPILGVCLGHQAIAETLGGNLRLAKRVMHG
RQSTIETQGPASLFRSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEI
MAFEHHTLPLFGLQFHPESIGTPDGMTMIANFIAAIPR