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# Dehalococcoides ethenogenes 195, 195

>DET0940 AMP-binding enzyme
MALENGKNNHFDKLESMGLEERVEFLNTRLKETAAYAYENSAATRAMFQK
AGLKPELIRKVEDLERLPITRKADLIEMQKQNLPYGGFLMIPEENIERIF
ISPGPVYEPLHTSTIHWFGRSFWAAGFRKADVVINTFTYHLSPAGILFHE
GLRDCGATPIASGTGHTEMQIKTIQELKVTAFVGTPSYLMSLFAKAEEMG
LDVKKELNIKRAWFTGEMLTSSIRKTLEKDYGIDTYQAYGVTETGGCLAY
ECEEKNGLHLMSDEYVVEIVDPKTGKQLGEGEVGEVVVTPVNNKTWGLMR
FGTGDLSCLKKEKCGCGRTAYKLSGIIGRVGDAVKVRGMFVVGKQAEEVF
KLFPEIVRCQIRINRPENKDEMTFVCVHDDTEFDAKKLSDELNKKFQDRC
LLKADHIEFVAANALAEETKLMLDERKWD
>DET1595 ApbE/NosX family protein
MKNKLTRRDFIRISAVGAGVLAAGGLGVKELITSAAECQYSETKTLLGTY
ITITLVDSSRDNAEAKVKDTFAEIERLSSVFNRFDITSELYRLNKSGQAI
GASSEFVSVLSSAQYCAELSGGAFDPTVLPALDLCQDSFAKTKLPPSVAQ
LDEVKYLVNYKEMSIKGKDVVLGRNGMALTLDGIAKGYIVDKATEYLRGR
GVSQVIVEAGGDLALQGMREDGQPWKVGITHPRAYTGYYDVIQSSNACLA
TSGDYENAFTPDYKYNHIIDPRTGFSPQELCSATVIARDTLLADALATAA
MVMGVDETLKLLESLDGAEALLIGKDLKSYTTSGYRALSEHLST
>DET0652 ABC-type cobalamin/Fe3+-siderophores transport system, ATP-binding protein
MFELEVRDITLAYGAVDVLRNVSFKTMPGEMIGLVGLNGSGKSTLIKSLA
RVIEPRLGHIYINGRDSRTIPRLELAKMVGVVPQIPVLPSAFTAFEIVLM
GRNPHMGTFQYESRKDIAIAWEAMERAGVLHLAERQIGELSGGEIQSVVI
ARSLCQKTEAILLDEPTSNLDIGRQIEVLDLIKSECRERNITVIAALHDL
NLAAHYCERLILIDHNGIHADGSPAEVITTENISRVYGPGSYVHTHPLSG
LPAVLPRLGNTRCANGEKGGTGAR
>DET0412 conserved hypothetical protein
MKVIALVGMPGAGKTEASRMFSKNGFIRIRFGDITDEKLRELGLPLNEEN
ERKVRESLRKQYGMEAYAVLNLSRIDENLKKDNVVVDGLYSWEEYKFLKS
YYKDKLIVLAISSSPATRYSRLCERADRPLNYENAVSRDYSEIENINKAG
PIVMADITLLNELDLKDMEKQVKKLSLELRADV
>DET0090 radical SAM domain protein
MMNTQVFHIGYCPELKEATLHYWGCNFKCRGCSCQKLIWDWMLEEFLDAR
DAEPLEIADAPHRFLSISEISAALEKLELRRVLHMGQEAILDPAYPVLAE
MIHRRFGCKNVLLTNGYEMPDLRHTDKVEFGIKAITNGLHRHYTGKSNKR
VLRNFKEIYNSGVEMVIESVFIPGYIDVAETERIVDFIAGVDKKLTYVLL
PYFKAGNNPWRRPTPAEMEMAANIARKKLTNVYFFRGDEDLQYKVISIFP
EAGSNTELEISETHCGVLNPV
>DET1137 radical SAM domain protein
MTANSHTPRIMPDRQANPDMTNVYHIAYAPGIKKAYLFHWNCNLKCRGCL
CKKEINCLALEENLDVVARDPHLAPPRGPESFLSLNGIMETLRKVELKEV
LFEGQEATIDPHFAEICRRLKAEFGVYITLNTNGLKLPDLSNVDEVVFSL
KAVTPELYLDYTEVPNTRMLENFENIFRSGKKLRAEMVFIPGYIDIAETE
VIAKHIASLSRDIPLRIDAYFECGDNTWRRATPEEMRQAVAAAKKHLNTV
TCTQQTTDNLDKKDLFFEVKRLF
>DET0849 biotin--acetyl-CoA-carboxylase ligase
MEKHMDEPVISLSDIKNNLHTCLMGREIIYLPETASTQTTAMDMARKGSQ
EGTLVITGKQTEGHGRLKRLWVSPQGNIYMSLILRPNQNQLSRLIMAASL
AVSFAIENTTGLIGELKWPNDILIDGKKVCGMLVENDIRDGQVNFSTVGL
GINVNTDMQSYPELKGIATSLINHTGKPVSCEKLIVSFLHEFERLYLGLN
EYGECIFEMWRKRLITLGKEVDVTSGKDTYRGIVESVVPDGSLKIRLADG
NLVHIVAGDVSLRHAE
>DET0402 methyltransferase, UbiE/COQ5 family
MVAPSFFEKVAPVYEFLTRMFMLGTFESARDRMLNEDTSAFSVLDLCTGT
GYIANKIEAKRIVGLDQSVQMMALNDRTKRPNKTLVRGNAYHLPFEDGEF
ERIYCSSASHEFKLFGKVLAECFRTLKPGGKVAVYDIYQPKNKFYSLIVN
TIYRYPVEHNIMWVHTLEEWRKLLTEAGFEVEELEAVRGVFVFVRARKPV
>DET0016 folylpolyglutamate synthetase
MGLTDYESATSRAAANYDLRRVVELLLRLHSPHIGIPSVHLAGTKGKGST
AALIASVMSAAGYRTGLYTSPHLLDFRERIRLDGKMISKAHLVRIMDYIS
PMVEEMNARTCLGKITSFEVMTVLAFEFFHRQQAFFQVIETGLGGRLDAT
NVITPNLSVLTPISLDHTEVLGDSLAKISAEKAGIIKHFVPVVSAAQRPE
AMAVIRERCLKTGSKLIEVTDSYKAELLGYTAQGQSLKLSGRQAEYRLCL
PLLGHYQRQNALTALASLEALVEEGFKISNEDIAEGFGQVRWPGRFKVIK
GKPLMVIDGAHNQEAAAELLLSLQEYPPAAKVEKEKRLLVFGTSFDKDAG
AMADVLSGYFGTVILTHSLHPRAMKPDLLRKAFDGRGLKVLEADGVPKAL
ELAGRIAPADGLVCVAGSLFVAAEALKGQSQPRSGTGSK
>DET0686 ABC-type cobalamin/Fe3+-siderophores transport system, ATP-binding protein
MFELEVRDITLAYGAVDVLRNVSFKTMPGEMIGLVGLNGSGKSTLIKSLA
RVIEPRLGHIYINGRDSRTIPRLELAKMVGVVPQIPVLPSAFTAFEIVLM
GRNPHMGTFQYESRKDIAIAWEAMERAGVLHLAERQIGELSGGEIQSVVI
ARSLCQKTEAILLDEPTSNLDIGRQIEVLDLIKSECRERNITVIAALHDL
NLAAHYCERLILIDHNGIHADGSPAEVITTENISRVYGPGSYVHTHPLSG
LPAVLPRLGNTRCANGEKGGTGAR
>DET0099 mobA family protein
MNLIITGEVGSGKSSHCQRYARYLREYGFKTGGIICHPVFQEDTKTGYTV
TDIRTSAEAVFSLTNPPADFQGEKVGRYSILQSGLDFACNAIKEALRTGY
EVIFLDEMGHLEIAGKGLAGQARLAYRKAPYTVSVVRKSLLQKFLAAFAP
EESENIFVIQDIEADPDIHPAFFKTPPAKTDISCIILAGGKSKRMGRDKI
SATLDSQTLLERAVANLNGYGREILVVTAYGQADAKIQPLPGIKIVRDIL
PEKGPLAGIYSGLKASKSQFNLVVGCDMPFLNRALLEYMKDQVAGFEAVV
PRLGQKPEPLHAIYSKSAGEKALSLLSQGKLAVSDLLARLHTRYIEEPEI
NRFDPEHRSFFNINRPEDLDTARDIAANKKAVSG
>DET0598 SNO glutamine amidotransferase family
MKIGVLALQGAFREHINMLRTLGAEAVEVRKAEELAELSGLIIPGGESTT
ITKLLYTFGLAKPVKDLARNGMPVWGTCAGMICLAKELSGDISGVKTLEL
MDITVRRNAFGRQVDSFEAMLKVKALEGGDFPAVFIRAPLVEKTGQWVEV
LAKLPDGTMVAVRENNLLATSFHPELSADNRFHRYFVQMAKDYKP
>DET0089 radical SAM domain protein
MSLTDIPKKAGSFSEMGYKLPVPDNNPAGGIRKSSPGTNIYHISYTPQTK
EVSLFFWGCNFSCRGCLSKKGTGNYLLPENIHLFRDNPAETVQPPVHFLS
VADVLSILGGLDIQTVLFEGQEPSLDESLPQLAKLIHTEFRTQNILCSNI
NKLVLLDDIDCIQLSLKAVTDSLHLDYTGKSNRNVLNNLKYLHAAGKKLS
IASVLIPGYIDKDEIELIAGFISDINQGLPFNILPYFKAGQNKWRCPTIS
EMEDSERIARKYLTHVYAWRGDEEIKYEVMKIY
>DET0296 precorrin-6Y C5,15-methyltransferase, putative
MPKLAALEAQKNGDTVVVLKTGDPLVAPAGLDGITSTFNGFEVEIIPGIS
SVQLAAAKAGISLYDAAIITYHPLPHDGGKDLRKKRRRMLDALSWGLHLI
VLTGVRQMPNATARCLLDRGIAPDSRVMVIENPACPDEKITSCSLADVSS
QRFGWFSVMVVFNKPD
>DET0858 oxygen-independent coproporphyrinogen III oxidase, putative
MTDTSLALYLHFPFCLQKCGYCSFVSYPARLDCLPDYVKCLRKEIKSRAS
GLYFHSLYFGGGTPSLLSPSQVADILAGIRTAAHLLPDAEITFEANPGTL
ALPYLPEIKSLGINRLSLGIQSFSGAELTMLGRLHNAAKARQAYKQARAA
GFNNISLDLIYGLPDSSVSSFKKNLAEALALAPEHISLYGLTLEEDTPMY
RQVQEGLLPEINAETAADQYQAAEDILAKAGYRHYEISNWAKPGYESRHN
LTYWQNRPYLGLGAAGHSFLENWRLANTSSLDEYLNRWQNDLPPTPSENI
YLDLENQLAETIILGLRLDKGITAEDIENRFGQHVMDKYFPVIQECTGLG
LLEKSDGGISLTPRGRLLSNEVFWRFLP
>DET1605 6-pyruvoyl tetrahydrobiopterin synthase, putative
MYYLSVKKHFEAAHFLRGYKGKCENLHGHRYEVALKVRANELDECGMGAD
FKVLKTSLGEVLQSYDHTCLNDLTPFDNQNPSAENISRDIYDKLKPVISR
MGVELRGVEVWESPDSSVLYQPD
>DET0398 ubiquinone/menaquinone biosynthesis methlytransferase UbiE, putative
MSSLAEAPIHDPGFDSEEAHKRKQYMVDLFVVQAKNYDFHDDVFGLYAHR
FWMRTVLKIMGRFLKDRKHVDMLDLACGTGFVTFNTARNFDNVDIEAFDI
SPDMLAVAKERYEKYFKGRNIKFWRGDAEVPFGEEKYDLVTTSFAYRNFA
NKGIATENVFNALKPGGLFIIQDLTKPERHPMRGLYIFYMKYILPVLTGI
LGTEKSAARWLYKSAMMMPTNGQIVKLMESKGFEKCQYKSLSLGIACVIW
GFKPEKSE
>DET0399 ubiquinone/menaquinone biosynthesis methlytransferase UbiE, putative
MSSVNVSVKDPGFESEEAQARKRYMLQLFGFQAKHYDLHDDIIGMGIHRR
WGKEMVLEILTYTRNMPQVKMLDLACGTGFVTFNTLRYMNNVDIDAFDIT
PEMVEVAKGRLKKNYPDRNVKFWVGDAEVPYGDAKYDVIGTCFAFRNFAN
KNLAASNIFKALKPGGLLVLQDMTKPEKQPFRGIYLFALKNLMPIMARII
GTERKSARYLANSVLAMPSNAEIMSILQNQGFINIKSRYQSGGMGTLTVA
YKPEN
>DET0380 pyridoxine biosynthesis protein
METGTFKVKSGLAQMLKGGVIMDVTTPEQAKIAEEAGACAVMALERVPSD
IRAAGGVARMADPTIIEKIMKVVSIPVMAKCRIGHFVEAQILESMGVDYI
DESEVLTPADESFHVWKHDFKVPFVCGCRDLGEALRRIGEGAAMIRTKGE
AGTGNIVEAVRHMRSVMGSVRRVQSMSADELSAYAKEINAPLELVLELHK
TGKLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIFKSSDPAAMAKAV
VKAVTHYKDAKVLAEISKGLGDAMPGLDIKQIEPDKLISRRGW
>DET0239 radical SAM domain protein
MSCHGCLCKEGIYDHLLKENRLGNLPQTENAFKPRRLLELDEVLARLDEL
KPQKVFLTGEEASLDPNYAAITRAFHERYGCKNVLYTNGFKMPALGDTDA
VEVGIKAISEELHQWYTERSVEPIKQNFIRYAHSEVKLTAASILIPGLVE
IDEIERIAQFIAGVNPDIPYFVLPYFPAGNNSWRKTSPYEVAEAVERVSR
YLTNVSGCQGVEQEILHEVERVV
>DET0240 tetrapyrrole methylase family protein
MAGTVSRIYYPRVFVTGVGTGGRAFLTPAAEETVKSCGIIVGWPEVIKNL
GFGLENKLVLEQNCLNYQQLLAEAAGLARAKLEDVALLVMDDPLVYSAGL
GGYSDIFKDFRIEFIPAVSSLQLLAASARLSLEDCLQVVYRPDASGNIDQ
SDLALKRERMLKALKAGYHILVLSDLEQTLAQTACFLIEKGLAVETGVIV
GEQMGTDSQKITEKSILEVSRDTSHWMSCMAVRQGKILKK
>DET0241 radical SAM domain protein
MDRQTNVYHVAYAPAIKKAYLFHWGCNLECRGCLCKKEINCMALEENLDV
VFRDPRFCPPQTPSAPLSFGKLISLLQDIELTEVAFEGQEASLDPMLPDI
CRWLKERGCKVILHTNGVAMADASHIDDVIVSLKAITPEIYAGYTCRSNS
SLLENFKEYYQAGVNLKAESVFIPGYIDLEETEKIARFIASVDENIPYRM
DAYFESGDNPWRPPTPEEMQTALEVARKHLKNVYCTQQTKQNLSKADLLY
EVVRLY
>DET1176 Fec-type ABC transporter, ATP-binding protein
MIEINDVSFAYNKAGKNVLEDISFDIQDNRCIAILGTNGAGKSTLLKCIN
RICPAQKGVVMVNSQSIFDMSSNAIAQNIAYVPQNNRAINMTVFDTILLG
RKPYIKWDASLEDRRIVYDIMQKMKLEDFALRNVSSLSGGEAQKVMLARA
LAQEPKLLLLDEPTSNLDPRNQHEVLRIVKSIAKEHNTCVAIILHDLNLA
IRYCDRFVFLKNSRIFSYGGLETMTPENIESVYRIHVHIMEYMNIPVIVP
FPDEKVAPELPSQTLPEPVSEA
>DET0782 ThiE-associated domain protein/thiamine-phosphate pyrophosphorylase
MDNLDKLWRIVDVNQNRLSEGLRILEEIARLYLEDETLTSRLKNLRHSLT
LQDITSNSRLLFSRQADTDIGAQLETADQSKPETLFSVVSANAKRAEQSL
RVLEEFAGLSETGLDAALYSRGRFELYTLEKDLAARLLRKHRRDMITGLY
VAIDADYLAGRDIPAVTREALEGGCRLIQLRAKTASTRKFLALAVNLKEI
CLEYGALFIVNDRLDIALACGADGLHLGQTDMPLSQARRFLPPDSIIGIS
ADTPEQAVSAQNEGADYVAAGAVFPTQTKPDVLFGGLSGLKAIHQVVKIP
LVAIGGINKSNFYEAMQAGADSLCLISAVLGAPDIKKATSEFITLMEAAK
ID
>DET1418 nicotinate-nucleotide pyrophosphorylase, putative
MPVKPKFNIPGNLLSGDTTDIYFARTVEILAKENQNPETVMEVFTTRPGI
LCGLSEAVELLQAVLPAGEGEIWALEDGDQISAKEVVMRIKAPYLSFGLY
ETVYLGMLASGTGWATAARECVEAAGDIPVTSFGARHIHPLVAGRMDYAA
MIGGCKGCSSIEGARLWGISPSGTIPHSLILVMGDTLKATLAFDKHMPPQ
VPRVALVDTFKDEVEESLRVAEAMGQRLDSVRLDTPFERGRVTADLVKEV
RANLDMAGHNHVKIFVSGGLTPERIRYFAENNAPVDGYGTGSYISGARPI
DFTADLHEIAGKAVAKRGRIPGLSQNPRLKKVR
>DET0401 1,4-dihydroxy-2-naphthoate octaprenyltransferase, putative
MKALTSERPDFQDWIQAARLKFLPQGVMPVVIAGALAFSEDTFDVVNFVV
AFSAAAAVQIGLTMFNDTLDYVYGTDCKHADAKNPFSGGSGVFTCGVIKP
RQSLLVIFSLYFFALLCAIYMALDMGWGVMWIAVIGAAISILYSAKPMRL
AYHGLGELMMLIGYGPVLTAWGYFVHTGMVNRDVLLIGVIPGLCMWAMIL
INEIPDYQEDRAAGKRNLTYRLGPKNAKNLFSISLAGLYTYILALVFTGV
MPPLSAISLGGIPLAVMAVRIAHRYYNDPIKVAMANKLMVIIYSVTTATV
AIGMLT
>DET0622 radical SAM domain protein
MKVYHLAYEPSYHSMDFHFWTECNLKCRGCYTNYEVYDFGLMDDPVAEII
THERQAPPTEFLSFDQVMEKIDGYTIKYAVFLGTEAVLDPELPKLAKAVH
EKYGSYNILLTNGIRMPDLTDIDQVIFSLKAYSEDIYRDYTSRSNKSALE
NLKKIHAALGDRKLHVEVVYIPDYIAKDEIEKVAQFLASIDKDMSFRIDA
YFPIPGCPWRAANKEEVEEAAEAARKYLNNVVVLTLDMKRIGDKAIKVF
>DET0037 PyrK family protein
MYTIVERQDLLPRVHLLKIQAPKVAAAAAAGQFVILRIDAEGERFPLTIA
DWDAQAGTVTVIYMEIGASTRKLAKLGEGDAILDFAGPLGKPTEIENFGT
VVCVSGGFAMATIAPIARAMKEAGNRVISVVGARSKDLFFWHDRLTKYSD
EMIVCTDDGSAGIKGVVTEPLRDLLASSTKVDRVIVIGPSVMMKFCSKTT
QPFGVKTIVSLNPIMIDGTGMCGCCRVSLDGQTRFACVDGPEFDGHKVDW
DGLLVRQKSYVAEEAVAAERCRCKEEGCGNHG
>DET0513 ahcY, adenosylhomocysteinase
MPNFDVKDMSLAALGKKRIDWAGREMKTLSLIKERFEQEKPFKGIRIAAC
LHITTETANLGLVLKAGGADLTLCASNPLSTQDETAAALVEHGINTFAIH
GEDNESYYRHIAAALDAKPQLTVDDGADLVATLHSQRTELLSGILGGTEE
TTTGVIRLRALAESGKLCYPIIAVNDAKTKYMFDNRYGTGQSTLDGITRA
TNFLWASKTVVVVGYGWCGHGVAMRAKGLGAHIIVTEVDPVKALEAVMDG
FSVMPMAEAAKAGDIFITVTGDKHVIDANHFKLMKDGATLANSGHFNSEI
NIPALETLACGKETIRPSVEEYKMKDGRRIYLLGEGRLINLAAAEGHPAA
VMDMSFANQALSLEYLVKNHTKLEKKVYAVPEEIDRAVAATKLSSLNVSI
DTLTEEQIKYLSSWQEGT
>DET0429 coaBC, phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase
MDKKKTVVLGITGSISAYKAADIASKLVAAGYTVKAVMTENACRFISPLT
IRTLSRQQVVTGMWDMNSEYSVEHVSLAEEAAVILVAPATANIIAELACG
LAGDMISSTILASKAPVIIAPAMNDNMYSNPATQQNIAKLKERGFVFVEP
ESGRLASGKTGQGRLASVDTILGSVTQVLGKNGPLAGKKLVISAGGTREP
VDPVRYLGNRSSGKMGYALAEEAVRRGASVRLVSGAVDKPAPFGVDIKYT
ETAMEMFISLREAVKGADALIMTAAVADYRPEKPAADKIKKGDGELDLHL
VANPDILASLQGDFVKVGFAAESRDLMINAVKKMADKNLDIIAANDISQP
DSTFGSDTTRLTLFFKNGRIEEMPLMSKQEAAVRLLDELSALL
>DET0190 coaD, pantetheine-phosphate adenylyltransferase
MIAIYPGRFDPVTLGHLSVARRASGFCDRLIIAVFDNPAKPGLFTAAERV
DLIKQSVKDLPNVEVHSFSGLMVNFARRMGVSLIIRGLRVGADFEREMEM
YVMNRRLDEGIELCCLFSEPQYQYLSASLIKEVVMLGGDSSGLISEHVAD
ALKNKLASA
>DET1323 coaE, dephospho-CoA kinase
MKIVGITGGIGSGKTTVCRYLKELGVNIIDADEIGHRVLQNKGIRTRITD
VFGNEVMNPDGSINRKILGELVFGYPERLEHLNKITHPLIEQAIASLLEE
YRQKGIKAVAIEAPLLVEAGWLKLVNEVWLITAPKESIFKRLRNRMGLSR
EQVMARIQSQATDNERLKYASIVINNNCRFEDLKSCVQLLAKERLELA
>DET0245 cobA-1, cob(I)alamin adenosyltransferase
MFKVSGKPQPGLVQVFYGDGRGKTSAAMGEIVRAVSAGLRVTVVFFMKGE
RRNAEYSSLKALGVEYAVFGRSSFLSGADARAEDARLCRQALKFAEGQIS
SGKWDLVVLDEINNARYYGFIETEDILKLLSVKPARTSLVLTGKTADKEV
AAKADLVAEFRKLKHPYDRGILARAGIDY
>DET1139 cobA-2, cob(I)alamin adenosyltransferase
MNDTPQTAKYHTGLVQIFTGDGRGKTSAALGTVMRASGYGLKAYIVFFLK
GLHEGGEYNSLKRLPGIDYAIFGRSDFMGPQYTTQADLDYARQALAEAKK
VILSGEYDVVMLDEINTASAWKLINVEDVVELVKSKPEKVELILTGRHAD
TRLVVLADQVTELVNRKHPFEKGVDARQGIDY
>DET1224 cobA-3, cob(I)alamin adenosyltransferase
MVTNHTPYLEKGLISIFTGEGKGKTSAAVGTAIRAAGHGLRVCLIFFAKG
KRFDHGEFKILSSLPNVTLQSFGQAGWILKNISEETRTQAERAFETASEA
VTGGQYDLVVMDEIMIALTAGLVTTEQVIRMINAKPPCVELIMTGRGAPA
ELIELADLVSEIKAVKHPYTRGIKARKGIDY
>DET0128 cobB, cobyrinic acid a,c-diamide synthase
MNFPRIVIAGISSSSGKTTISSGITAALTKRGHKVAAYKCGPDYIDPGYL
TLAADNPCHNLDSWMLGKDAMTEVFFHGLKNREIALVEGVMGLYDGYSGE
RPGGSTAEIARLLSAPVILLLNISHMAESAAAIVLGYKNLDPRINIAGVI
LNQAGSLRHYEICRKAIEKYTSTPVVGYLLRNKELAIPERHLGLKTTSEG
GELASFIQNLAAHIESTIDIDRILNIARNAPPLPERPCPYLFPETPARPV
TRIAIARDEAFSFYYQANLDMLSDWGAELCYFSPVHDTCLPENIGGIYIG
GGFPEIMAAELSANQAMKTALTKAAEDGMPIYAECGGLMYLSEAIEDFDN
NKYLMLGLLPGVSVMQKKLHRLGYTRAAVQNDNILSGKGTELRGHIFHWS
KLPSPKTKPAYTLLEPAEYAGQNEGFIIGNSTNVLASYLHLHFGTNPDLA
KNFIRVSKGFYAI
>DET0246 cobD-1, cobalamin biosynthesis protein CobD
MNEYILILILAVLWDLALAEPPAAIHLTVWIGRVISLVEKAGLKIRSRAL
QYIFGMAASLFLIALFGWLTYLLLDYLGGLSFALYLIAAFLILKTTFCLR
FNARMSLLVEKYLKGGDYRIESAAPEIRYLLTTVERDKEDGFAPPMISST
IRSLAENASDFLVAPLFYFLILGVPGAVAYRVCNTLDGMLGHRGEYEYLG
KFAACLDDIINYLPSRLTGLMFILAAFVSGMDGQNAWRIALRDQSKTESP
NAGWPMASVAGALGVRLERAGHYALGDAAKPLSPGHIGQAVRLFGVMSAI
SIAISTGILLAVYLISLN
>DET0654 cobD-2, cobalamin biosynthesis protein CobD
MEVLFIFLLALIIDLVFGDPPNAFHPVAYMGRVIALFERAGFKGGRVYQF
VYGIVMVFIAMALFFIPVYFLLDWLHGVNSVVYIIVSAVLLKMCFTVTGL
RKAALLIKQLLEKDDIAQARFELRSLVSRDTSKLPQPKLVAAAVESVAES
IGDGFVAPLFFFLIFGVPGVMAYRVVSTFDSMVGYRGKYEYLGKFAARFD
DVLNFIPARLSALCILIASLFGRYSPAGAWRIMWRDHAKTQSPNAGWPMA
TAAGALEVCLEKVGHYSLGDNIRELVPQTISRSLLLINSAAFIWVLISAG
VIYFVRIA
>DET0688 cobD-3, cobalamin biosynthesis protein CobD
MEVLFIFLLALIIDLVFGDPPNAFHPVAYMGRVIALFERAGFKGGRVYQF
VYGIVMVFIAMALFFIPVYFLLDWLHGVNSVVYIIVSAVLLKMCFTVTGL
RKAALLIKQLLEKDDIAQARFELRSLVSRDTSKLPQPKLVAAAVESVAES
IGDGFVAPLFFFLIFGVPGVMAYRVVSTFDSMVGYRGKYEYLGKFAARFD
DVLNFIPARLSALCILIASLFGRYSPAGAWRIMWRDHAKTQSPNAGWPMA
TAAGALEVCLEKVGHYSLGDNIRELVPQTISRSLLLINSAAFIWVLISAG
VIYFVRIA
>DET1138 cobD-4, cobalamin biosynthesis protein CobD
METVYIIVLALALDLLLGEYPAPLHPVVWLGKFISFLNRFSPSHSPKIQF
IYGAFLSILTVSISFAAVFFILGYLKDFNTLLYIIAGGLMLKPAFCLRKQ
WTIALKIKKLLGNNSNSVPPKELETLIGTVPHTQEGLSRKDIVSASIRSI
SENASDFFVAPLFYFIFLGVPGAFAYRAINTLDSMIGYHGQYEYLGKFAA
RLDDTANFIPARLTALLFVIGAFILRQNPKRALHSAVADHARTTSPNAGW
PMAAMAGAIGISLEKANCYTIGKPLHPLSDTDLSVAVRLYKASMFIWAGI
CIAIAWI
>DET0936 cobQ, cobyric acid synthase CobQ
MNAMAKLIMVQGTSSNVGKSILVTALCRIFKQDGYKVAPFKSQNMALNAF
VTQEGGEIGRAQAVQAEACGIAPSVDMNPILMKPEADSKSQIVVNGKVDR
TISAREYYEYAPLLLDTALAALNRLREQNDIVVIEGAGSPAEINLRQREI
VNMRIAKTAGAPVLLAGDIDRGGVFASLIGTIDLLEPEERSYVKGYLINK
FRGDASLLKPAIDVLEDRTSIPVLGIIPYLRNMAIAQEDSVYLDECKSGL
GETDLDIAVIRLPRISNYDDFDALATDGASVRFVSKTGEIGNPDLIIIPG
TKSTIPDMEYLWQNGLAETIIKKAGKGTHVLGVCGGYQILGKMIYDPHKT
ESETTELKGLGLLDTETTFEKEKSTTQVSGQVRFNNGLLADMAGCEVGGY
EIHMGRTRLFTAQPAFQITKTPKGPADYLDGASNAEGTVLGTYIHGIFES
DSFRRGFLNAIRRYKGIPERQAGYFDRDKEYDKLADIVRASIDMNKIYDI
LNEGIR
>DET0658 cobS-1, cobalamin 5'-phosphate synthase
MGSFLAAFRFLTNIPVPWLKEDWQGEKSHLDFARSLGFYPLVGLIVGLIL
AVLGWVFSLFLPDVLTAALLTVSLVVITGGLHLDGLTDTFDGIAAGHKSF
ERAQEVMHLPGVGAIGVLAAICLLLSKFAAIVSLPSGSFITGLILFPVIS
RWAMVYAVVCYPYVRSQGLGKELKGGSAKASLWLATIFCLAVCVILGGWA
GLLAMFGSWLLIMYLASFFRRRLGGLNGDTYGSINEFTEVAALIFIVALS
GYFS
>DET0692 cobS-2, cobalamin 5'-phosphate synthase
MGSFLAAFRFLTNIPVPWLKEDWQGEKSHLDFARSLGFYPLVGLIVGLIL
AVLGWVFSLFLPDVLTAALLTVSLVVITGGLHLDGLTDTFDGIAAGHKSF
ERAQEVMHLPGVGAIGVLAAICLLLSKFAAIVSLPSGSFITGLILFPVIS
RWAMVYAVVCYPYVRSQGLGKELKGGSAKASLWLATIFCLAVCVILGGWA
GLLAMFGSWLLIMYLASFFRRRLGGLNGDTYGSINEFTEVAALIFIVALS
GYFS
>DET0657 cobT-1, nicotinate-nucleotide-dimethylbenzimidazolephosphoribosyltransferase
MELLNATLAKIHGLDKEAMTKAQAHQDILTKPQGSLGKLEAIAVQLAGIQ
GNAKPQTARKAIITMAGDHGIIDEKFHNWPKEVTAQMLQNFAHGGAAINV
LSRQVGARNVVVALGVATPMAEDPNIINRNIAPGTNNMVYGPAMTREQAV
KAIETGIEIVNAEVKKGLDLVGTGDMGIGNTSPSAAICSVITGRSLEEVT
GRGTGASDEQMKLKRNAIAKAIALNKPNAQDALDVLSKVGGYEIGGLAGV
ILGAAANRVGVVVDGFISGAAALIAYTICPQAKDFMFAAHQSVEPGHRIL
LEHMGLDAILKMDMRLGEGTGAALAMNIIEASNRIQHEMASFADAGVSEK
QS
>DET0691 cobT-2, nicotinate-nucleotide--dimethylbenzimidazolephosphoribosyltransferase
MELLNATLAKIHGLDKEAMTKAQAHQDILTKPQGSLGKLEAIAVQLAGIQ
GNAKPQTARKAIITMAGDHGIIDEKFHNWPKEVTAQMLQNFAHGGAAINV
LSRQVGARNVVVALGVATPMAEDPNIINRNIAPGTNNMVYGPAMTREQAV
KAIETGIEIVNAEVKKGLDLVGTGDMGIGNTSPSAAICSVITGRSLEEVT
GRGTGASDEQMKLKRNAIAKAIALNKPNAQDALDVLSKVGGYEIGGLAGV
ILGAAANRVGVVVDGFISGAAALIAYTICPQAKDFMFAAHQSVEPGHRIL
LEHMGLDAILKMDMRLGEGTGAALAMNIIEASNRIQHEMASFADAGVSEK
QS
>DET0660 cobU-1, cobinamide kinase/cobinamide phosphate guanylyltransferase
MNYLLIGGARSGKSSYAEELAKSIGGNIVFVATAEAGDDEMKTRILRHQQ
ARPPEWGLIEASLGVGEKISAHGKNADVIILDCITLLVNNIMCRYMLEHG
DELTGDAADYLDAAVKKEINDVIKAMEKTGASFIVVTNDVGAGLIPPNAM
ARIYRDLLGRANQMLGAYVEYVYLMVAGLPMQVKPLLR
>DET0694 cobU-2, cobinamide kinase/cobinamide phosphate guanylyltransferase
MNYLLIGGARSGKSSYAEELAKSIGGNIVFVATAEAGDDEMKTRILRHQQ
ARPPEWGLIEASLGVGEKISAHGKNADVIILDCITLLVNNIMCRYMLEHG
DELTGDAADYLDAAVKKEINDVIKAMEKTGASFIVVTNDVGAGLIPPNAM
ARIYRDLLGRANQMLGAYVEYVYLMVAGLPMQVKPLLR
>DET0745 dxs, 1-deoxy-D-xylulose-5-phosphate synthase
MHTGLEISIPHNLQMSKLLDTINSPSDLKKLTLDELRELAVQIREELVNR
VTLNGGHLASSLGVVELTIALHRVFESPKDKIIWDVGHQSYAHKLLTGRR
EQFATLRQHGGLSGFTCRDESPHDPFGAGHASTSISAGLGMAVARDLAKE
DYSVISVIGDGAISGGMSFEAINNAGHLHTKFIVILNDNGMAISPSTGAL
SKFLNNVRFDPRFEFAKRGAKQTITNMPFGKSVWAFTKSIKRKFEKSMLP
GSLWEELGFIYLGPVDGHNIRELEAALKCAKDFESQPVLIHMITKKGKGY
DDAEADAVKYHGIAPKSGGLKSGHGLSYSQVFGQTLHKIMSDNPKVVAIT
AAMTDGCGLSEVAADFPDRVFDVGICEQHAVTFAAGMATQGYIPVVVIYS
TFLQRSFDQIIHDVCLQKLPVVFAIDRGGIVGDDGKTHQGIFDLSFMSLI
PDMIVTAPSDENDLQHLLYTAVNSGKPFALRYPRGFGEGVETEGTLRNIP
IGENEVLASGSEIAIFATGKSVAFAKEAMEILAESGIKPTLVNNRYISPL
DTELILKIAGNHKYLITVEENVLSGGLGSRINTILAEAGLVNAVKIANIA
VPDKFVEHGNQSLLRAKYGLDGKGIAQKVLSLMANTGEAKHQQILCP
>DET0668 folD-1, methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
MSAHIINGTEIAAAIREEIRSEVTALKAKHGIVPGLATVLVGDDPASHSY
VDSKIKMCQNLGIYSEHHPLPQSATNEDLLTLIARLNADPKISGILVQVP
LPVQISENLVLNAINPDKDVDGFHPVNVGRMCLGEPCFLPCTPHGVQELL
IRSGIKIEGTHVVIVGRSNLVGKPLANILLQKAPGANATVTICHSGTKNL
PLITSQADILVSAMGKPKFITADMVRQGAVVIDVGTTCIGYTPEGKRILS
GDVDFEAVKEKAFAITPVPKGVGPMTIIMLMLNTLTAAKRAAGLVK
>DET0702 folD-2, methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
MSAHIINGTEIAAAIREEIRSEVTALKAKHGIVPGLATVLVGDDPASHSY
VDSKIKMCQNLGIYSEHHPLPQSATNEDLLTLIARLNADPKISGILVQVP
LPVQISENLVLNAINPDKDVDGFHPVNVGRMCLGEPCFLPCTPHGVQELL
IRSGIKIEGTHVVIVGRSNLVGKPLANILLQKAPGANATVTICHSGTKNL
PLITSQADILVSAMGKPKFITADMVRQGAVVIDVGTTCIGYTPEGKRILS
GDVDFEAVKEKAFAITPVPKGVGPMTIIMLMLNTLTAAKRAAGLVK
>DET1204 folE, GTP cyclohydrolase I
MFDEQAIKQSVQNMLLAIGEDPEREGLKETPRRVAQMYAELFSGMNQDPA
EVLRVGYELGHREMVIIKDIPFYSMCEHHLLPFSGVVHIGYIPNIDGRVV
GISKLARVVEIYAKRPQIQERMATQIADAIIDGLKCDGVAVVIEAEHMCM
VMRGIKKPGSRVITSALRGSFHKSPAARAEFLSLIQQKH
>DET1604 folK, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase
MEIIYLGLGSNTGEREQNLKDAQSRLSEKISISGLSTIYETKPLNCPAQP
DFLNMVLEARTELSPQDLLAFTQKVEQDMGRSPSSHNQPRIIDIDILLYG
QKRLNTPALTIPHPGLTERAFVMLPLVELAADFIYPGSRLSLSELLEELP
PGQSIRPFSRLPQSGEDTAEDDEEDE
>DET1603 folP, dihydropteroate synthase
MDLPAKKPVESLFGSKQFGWGERTYIMGIVNVTADSFSGDGLGANPEAAL
EQARRFALEGADILDIGGESTRPGSQPVNTREELDRVIPAVRLISRNLDI
PVSVDTYRREVAEEALKAGACIINDVWGLKKDPSLFELAAKRPAGWVITS
NQRENPAEDIMAAVTSELRETALRLLGLGVPARNIIIDPGVGFGKTLEQN
LEIVRRLSELKTLNLPILLGTSRKSLIGQVLDTPPGERLEGTAATVALGI
GGGADIVRVHDVAYMKRVCRMSDAVVRGKIWK
>DET0389 hepT, heptaprenyl diphosphate synthase component II
MLKLSSIYAPINEGLKGVEDEFKLVSESRKQSFPEMAEMLDYILVGGKVL
RPALSMLSAMCFGTGIKKVLPLATSSEMLHIATLVHDDAIDKADTRRSRR
TVNSVWGLEKAILLGDFLFAHAAEVAAETDNMRIVTLFAQTLQIIASGEL
KQAYASFNPDQSYENYLERISGKTAALFVMATKGGAILADASPSDEEIMR
SYGYNLGLSFQIVDDILDFVGNAKDMGKPVGSDLNNGTVTLPALLLMDRY
PENNPIKDMLGATDRSAHVARAVEMINSSDIIDLSYKEAKRYADLACQDL
SKLPKTAARESLYQLAEFIVERKN
>DET0833 ilvB, acetolactate synthase, large subunit, biosynthetic type
MKLTGAQIVCESLLKEGADVIFGYPGGVLLPLYDTFPQYPALRHILTRHE
QGAAHAADGFARVTGKVGVCLATSGPGATNLITGIANAYMDSIPMVAITG
QVTRNLIGKDAFQEIDITGITLPITKQNYLVTRASALADTIKEAFYLART
GRPGPVLIDIPKDVFIEQAEFEYPDEPDLPGYKPVIKGNLMQIQKAAKLI
ETAEKPVIIAGHGVNISGANEELKTLAENCQLPVITTLLGVSSFPEDHIL
SYGMLGMHGMAYANMAVAATDLIVAIGMRFDDRVTGKLSAFAPHASVIHI
DIDPAEIGKNIRVDVPIVGDVKTVLKSLNKQVECVQHSEWLRQLENWRRE
HPPLSIRHTDLILPQYIVQQISEATSGNAIVVTGVGQHQMWAAQHYTYIR
PNSLVTSGGLGTMGFDLPAALGAKVGCPDETVWCIAGDGGFQMNMQELAT
IVQERAAVKIAVFNNGYLGMVRQWQDLFYNKNYVATPLGCPDFIKIAEAY
DIPALNVKRKEEVRPAIEQAMATEGPFLINFIIEPEENVYPMVPPGAALH
EVLEEPKKEVSACPRRSIP
>DET0831 ilvC, ketol-acid reductoisomerase
MAVIYYDKDCDLSLIEKKIIGIVGYGAQGHAHAQNLRDSGLKVIVACVEG
GRGWKKATADGFEVMCVAEMAKKADIIMMLAPDTSQAKIYKDSVEQGLTP
GKMLMFAHGFNIHYGQIVPPSFVDVTMIAPKCPGYMLRQVFTEGAGAPSL
IAVEQDASGKAKEIALAYAKGIGSNRAGVLETTFAEETETDLFGEQAVLC
GGTTSLVKAGFETLVEAGYQPEVAYFECLHELKLIVDLMYQGGIAYMRDS
ISDTAKYGDFTRGPRVINEETYETMGEILGEIQDGSFAKEWILENQAGRP
VYNSLRRMESEHLIEEVGAELRSMMSWLKKKK
>DET0009 ilvE, branched-chain amino acid aminotransferase
MGTSYAYFKKQIIPLEDAKIGVMTHALHYGTGVFEGIRGNWNNEKKQMYI
FRLKEHYTRLLTGAKVLKMNLPYTVDELCKITIDLIKKCGFKEDIYIRPL
AYKSSETFGVRLHNLDCDLLIVAIPWGRYIDKDTCHCCVSTWHRPDDNVM
PPQLKSTGIYLNNAFTKTEAVENGFDEGIMLTPDGHVSEGSGENLFIVRK
GKLITPPICDSILDGITRNSVMELAEKELGLEVLERSIDRVELYIAEECF
LTGTAAHLTPVSEVDHRKVGNGEIGPVTAKLKDLYFEAIKGNIAKYSSWC
TPVYNL
>DET0067 metK-1, S-adenosylmethionine synthetase
MTTYKTAESVCMGHPDKLCDLIADSILDACLRKDKSARVACEVMATKGKI
IVAGEITCDGKVDIRWEVREVLRKVGYNPWKFTVFVFVHKQSADISAGVT
TALEARNGSEERYASIGAGDQGTVYGYATNETREMLPLPLVLAHRICKRV
DTVRKDKIVKGILPDGKAQVTVEYEDEKPKRVKTIVVSVQHEASKTQEQL
YSDIKQNVLWQCFEDFPFDDDTEIFVNPSGRFVEGGPAADTGLTGRKMMV
DTYGGLALHGGGAFSGKDPTKVDRSGAYMARYIAKNIVWSGLADKCGVAL
SYAIGKADPVAVDIDTFGTSALSNETLREIVMSVFNLRPAAIIEKLVLRN
AIYEDTATYGHFNSCLFPWEDTSMRLYNELRKAAEAYADRKTEN
>DET0512 metK-2, S-adenosylmethionine synthetase
MSQTFGNSSKYLFTSESVTEGHPDKICDQISDAVLDAIIAKDPNAHVACE
TAVTNGLVVVMGEITTSCYVEIPELVRGVIKDIGYTKPEYGFDDRTCGVL
TSINRQSPDIALGVNKSQEAKSGQVDELDLTGAGDQGMMFGYACTETPEY
MPLPISLAHRLSKRLSEVRKNGTLAYLRPDGKSQVTVEYHNGEAKRISSV
VIGAQHDPDVTTEKIQADIIREVIKPIIPTNLLDENTEYYVNATGRFVVG
GPVSDTGFTGRKILVDTYGGFARHGGGAFSGKDPTKVDRSACYMARYIAK
NLVAAGLADRLEIQVAYVIGVAHPLSVSIETFNTARMSHEDILSIIQKHF
DLRPEAIIRNLGLRRPIYRQTAAYGHLGRPELDLPWERLDKVDAIKATME
SLSVSK
>DET1590 nadA, quinolinate synthetase complex, subunit A
MYTELISHKIAELKKERKAVILAHNYQLGEIQEAADFVGDSLELARKAAN
IDAEVIVFCGVHFMAETAAILSPEKTVLAPEPKAGCPMADMISGAELREF
KARYPGLPVVCYVNSTAEVKAESDICCTSANAVKVVESLKSDTVLFVPDQ
YLGAFVQAHTAKKIISWPGYCPCHARIKPEDILNLKKHYPKAKVVVHPES
RPEVTALADGVLSTGQMVTYAARADVKELIVGTEIGMLYRLRKENPNKLF
IPVSEQAVCANMKMTTLPKLLASLENMQTVVSVPEEIRRKAVGAVERMLK
VT
>DET1382 nadC, nicotinate-nucleotide pyrophosphorylase
MSQSQIEKIIDNACDEDFARGDITTETLIPSSLAGRAIIVAKQDGIMAGA
EVAKIVFMKHDPNMEIDILIEDGKKIKAGDVVMVLNGRVINILKCERTAL
NFLTHLSGIASLTAKYISKVEGLNVSLADTRKTIPGMRMLEKYAVYAAGG
KSNRPDLACGVLIKDNHLMALSAKGIGIKEAIEKAKTNKSKLPVIVEVNT
LEQVAQAIEAGPSSILLDNMSVEDMKKAVDIIPETIKIEASGNINLDNIR
EVAMTGVDVISVGALTHSAPSLDFSLEFPVQQETE
>DET0003 nadD, nicotinate (nicotinamide) nucleotide adenylyltransferase
MVSLKTGILGGTFDPIHTGHLILAEEVKKRLGLDEIIFIPTGQPYYKADK
TISPAADRLNMVKLAISGKPYFRVMDIEIKRSGPTYTADTLNDLKLILPE
KTELYFILGWDNLEALPRWHKASEIIRLCQLVAVPRIGQAKPDVDELDDK
LPGLQQSLIMLSKPEVDVSSSLVRERLENGQGVEHLVPEAVAAYIKEHGL
YHRQ
>DET1015 paaK, phenylacetate-CoA ligase
MVIRSPEYETLPRPQLEALQLKRLQETVSYIYERNPFYRQSMDKLGVKPA
DIKTLKDIARLPFTSKEDFRQNYPFGLCCVPKNEISRIQSSSGTTGKPVI
APYTAKDVDTWAELIARSLSCAGVVPEDILQNAYGYGLFTGGLGLHYGAE
KLGVAVVPASTGNTKRQLMLLQDLGTTVISCTPSYSLIMYEAGKEMGLDF
HNSSLKLGIMGAEPWSENMRREIEAKLGITALNIYGLTEITGPGVAMECP
QKCGLHIWEDNFLVEIINPETGEVLPYGQKGELVITTINKQAQPVLRFRT
KDITSLMPEKCGCGRTMVRMAQISGRSDDMIRVRGVSVFPSQIESVLLTV
EGIEPHYQIIVDRHNAFASDELEIWVEVSEGIFSDEMAGLNALQKKLQAE
LDSVLGIRAKIKLVEPRSLARTEGKAKRVIDRSELPENR
>DET0803 panB, 3-methyl-2-oxobutanoate hydroxymethyltransferase
MVVLGYDSTVSVTMEDMLHHLKAVVRGSQKAMVIADMPFMTYHLSPEQAL
LNAGRFMQEGGAQAVKLEGGVNVADKVKRIVDCGIPVMGHIGLTPQSVNQ
LSGFKVQGKTLTAALALLEDARALEKAGAFAIVLETMPAELAAMITAAVS
IPTIGIGAGENCDGQVQVVSDMLGMFTDFVPKHTKKYADLNGIISKAVSG
YVTEVAKGEFPTLKESFTLDKKVLEELKKCVSSEQ
>DET0804 panC, pantoate--beta-alanine ligase
MQKLHREICGPVGLVPTMGYLHEGHLSLIRASKKQDLNTVASIFVNPTQF
GPHEDFKKYPRDEKRDMAMLENAGVDYVFAPSVEEMYPPGFDSWVEPGVL
QERLEGAVRPGHFRGVCTVVAKLFTIICPAKAYFGQKDYQQYLIIKKMAS
DLNLDVSVEMLPIVRESDGLALSSRNTYLSASERKAALVLYRSLLTAKSL
FAAKEYNPEIIRRKMTEEIQRESLAEIDYVSLSDQDTLGEADKVSIKTIA
LVAARFGKTRLIDNMFLA
>DET0802 panD, aspartate 1-decarboxylase
MLKSKIHRATITDACIDYEGSITIDKNLMQAANLLPYEQVHVVNVNNGTR
LETYVIEGPAGSGQICLNGAAARMGMKGDKVIILGYSLITEEDTLTHQPN
LVYVDSLNRITKVKNGVASRNLEV
>DET1203 pyrK, dihydroorotate dehydrogenase, electron transfer subunit
MTTTQLNQLSASVIENEEVMPGICLMWLEAPEIAASARPGQFVMLSCGGE
NLLRRPISIHQCHRENGLIALMYAVVGKGTDWLSKLQTGDSLSVLGPLGN
GFRVNEDSRHLLLLGGGLGIAPLRFLADEALKQGKRVSLIQGARTELQVC
PSHLLPEDASCHVTTENGAIGKKGLITHHLAEFLPDADQIIACGPMPMLK
ALAKEPQLSGKDIQVSLEVRMACGLGICYGCAVKTIKGMKTVCHDGPVFD
IRDIHWDEVKI
>DET1188 ribBA, 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II
MPNARVEDAIADIKAGRFVIVVDDYDRENEGDLVMASEMVTPDAINFMAK
NARGLICVSLTAERLEQLKIPMMVTENTSPYSTGFTVSVEARKKVTTGIS
AADRAATVQVLIDPAATREDIAMPGHMFPLRAREGGVLVRAGHTEASMDL
TRMAGLYPSGVLCEIMNDDGTMARLPQLEAKAAEWAIKIISVKDIISYRR
RTEKMVKKITEAELPTSHGQFKAVAYKSQFDADEHIALVMGDISGPEPVL
VRVHSECITGDVFGSKRCDCGEQLDMALNQIAKAGRGVLLYMRQEGRGIG
LHNKLCAYALQDKGLDTVEANIELGFAPDLREYGIGAQILVDLGLSKIRM
MTNNPKKVVGLEGYGIQVVETVPIIVEPNSFNRHYLETKQKKMGHLLNVD
KTN
>DET1190 ribD, riboflavin biosynthesis protein RibD
MKYMSQALSLAKLAIGQVSPNPAVGAVIVKNGEVVGQGFTQPPGGDHAEI
VALKQAAEKAKGAALYVTLEPCCHQGRTPPCTVAIIESGIKEVYIATLDD
NPLVSGKGKKELEDAGIKVHLGMMEREARQMNEAYFKYITTGMPFVTAKY
AMSLDGKTGTRTGDSKWISNEESRHFAHYIRHISDVIMAGLNTILKDDPH
LTARVNCGRGGTSHCQPTRVIIDDNGRAPLSSNVFHVPGNTIVAVAKGLT
PEEKQAYDEVGAKVVEMPDERGLVDLKSLLRYLGQNGVTSVLVEGGGIVL
GSLFDLKLVDKVLVFVAPIIIGGKDAKIPVAGLGAELITDSAKLRDITTT
AFGQDVLISGYVIKE
>DET1189 ribE, riboflavin synthase, alpha subunit
MFTGIVEELGFLKARNPAYLHIGAKLVLESLKVGDSIAVNGVCLTVTSFD
SSSFHADIMPETLRLSNLGKLSSDSPLNLERALTLNSRMGGHLVQGHVDG
TARLVSSVPDGSARLLTFETDQDLTRYMVHKGFVAVNGVSLTITDLQAKR
FSISLVNLSGKSTNLGLLKPGDTVNIETDIIGKYVEKLCRTERGISPEFL
AENGF
>DET0602 ribF, riboflavin biosynthesis protein RibF
MTLLEEEIIRHSSDQNTLITIGVFDGVHLGHQHLINELKKQAKERNLQSC
LITFKDHPSKVLGQDDIKLILSLEERNLALSQMGLDQIIMLSFTPEISTV
SATDFVGYLLDHLHMKGIVVGSDFALGRNRAGDATALRRLSHIMDFSVSV
VSPVVIENQIVSSTAIRRALLSGNVSKARLMLGRNYHIRGTVQNGANRGT
KLGFPTANLTLPGYLALPADGVYAAKAFLGEKEYNAVANIGSCPTFGQEE
HRLEVHLLDFAGDIRGQVLKVEFVEFLRPEICFADAEALKTQISADISKA
RDILR
>DET1187 ribH, 6,7-dimethyl-8-ribityllumazine synthase
MGKEFSGVLNGQGLKVALVVSRFNEFITSKLLSGAKDSLERHGVSADNTD
VAWVPGAFEIPLVAQKLAKSGRYDAVICLGAVIRGSTPHFEYVSSEVSKG
IARVGLDASLPVIFGVITADSIEQAIERAGTKMGNKGFDAATQAIEVANL
MKNLG
>DET0599 serA, D-3-phosphoglycerate dehydrogenase
MKKVLVSDALSATGLSPLKEIAQVDVKTGLKPEELVSIIGEYDALLVRSQ
TQVTADIINAGKKLQVIGRAGVGVDNIDLKAATGNGIIVVNAPTGNTISA
TEHTLALMLSMARHIPRANASLKSGQWKRNEFVGSELKGKTLGIVGLGNI
GSEIAKRALALEMRVIGYDPFISMERAKKLQVELVPFEDLLKQADFITLH
VPMTGQTKGLIGPKELEMMKPTVRLINTSRGGIIDEEALAAAIREKRIGG
AAIDVFSKEPCTESCLFECDNIIVTPHLGASTAEAQELATSDVVKQVIDV
FEGRPARYAVNAPYISAESLPVVGPFMPVARTVGSLVSQLTDGHMKNVTI
KYCGELAAYDTTALKALVLGGILEHISEERVNVVNADIVAAQRGLGVTEQ
KESACQNFSSLITVTIDTDNGKSNTVAGSLVRGDVHIVRLNDYWIDIVPT
GGYFLFADHIDRPGLIGAAGKITGDADINISYMHLSRQKARGQALMILAL
DEPLPEKQRQQLLSLPDVQTVQVVKI
>DET0775 thiC, thiamine biosynthesis protein ThiC
MTQLKQARKNIITPGMKAIAKIEGLPPEFICQGVADGNIVIPANKLRKNL
KLCGIGKGLSTKVNANIGTSTDFGTVESEVEKLKMAEMAGADTIMDLSTG
PKINSVRQSILKNTCLPLGTVPVYQAAVEAKDRYGAMVKMTADDLFSAIE
SQAKEGVDFVTVHCGVTRQVIDTFKGQGRLTDIVSRGGTFTAGWMVFHQA
ENPLYEHFDHLLDICREYDVTLSLGDGLRPGCIADATDRAQVAELLVLGE
LVKRAREAEVQVMVEGPGHVPLNQIEANIRLQKSVCEDAPFYVLGPLVTD
IAPGYDHITGAIGGAVAAAAGADFLCYVTPAEHLSLPDVTDVRNGVIASR
IAAHAADIVKGVNGAAERDRQMAIARKKLDWDSQLNLSLDPEHAKLTRDR
FKTKGKACSMCGDFCAMELAEKHLGVSVSRC
>DET0397 thiL, thiamine-monophosphate kinase
MKVSDIGECQLIDQLNKLLHQGTDETTPARQNLILDIGDDAAVFRPQGYQ
LVTVDSLIENVHFNRSMLNWADLGYKALAINLSDIAAMGGVPQYAIVNID
LPPDTLVSSVTDCYNAMRSLADKYQTAIIAGDTNQSSLINLAVTLLGSAE
NPDKLLTRNTALPGQKIAVTGYLGNAAAGLDMLLNQTKVPDESREIFCRS
FYRPEPRINEARLLVKEGARCCIDISDGLAADLLHILRQSRVSARIELER
LPVHPSLRLCYPLQAQHMALYGGEDYELLFTAPAKVIEQISAQSGIPVTI
IGEIIPGKPDELKLVDKDGRALQPEKNGWEHFKKPK
>DET1481 trpE, anthranilate synthase component I
MYYPSLAEVKKLAAQGNLIPISCEIMADLETPVSAFLKIKDSQNAFLLES
VEGGERVARYSFIGTNPHKVLTAYQTDTVPPLTQVENELNKYRVVPVGDL
PRFCGGAVGFLGYEAVTRFEELPSPSADPLNLPEAVFMLVDTMLVFDHIS
HSIKVLSYVHTEQDIETSYNQAIRNIENLVNRLRKPLPETAPKSTAASIP
EMKSNFKQADFEGKVSKIRDYLNSGEAIQVVLSQRLSRPTSAHPFDIYRA
LRSVNPSPYMYYLDFGDFQIVGASPEVLVRVEDGEVMTRPLAGTRKRGKT
QKEDTSLEQELRHDEKECAEHIMLVDLGRNDIGRISQPGTVRITDVMDVE
RYSHVMHLVSHVQGKLKPNITPFEALQSCFPAGTVSGAPKIRAMEIIAEM
ETEKRGIYAGAVGYFSYSGNMDMAIAIRTMVVKGGIAHIQAGCGIVSDSV
PEHEYQETLNKAQALLKALDRAENQASEKPHVITN
>DET1482 trpG, anthranilate synthase component II
MLLLIDNYDSFTYNLFQYFSELGQEVKVVRNNKITLDAIEALGPEYIVIS
PGPSSPLQAGMSNDIIRHFGPRLPILGICLGHQCIGHTYGGIVRQADRIM
HGKQSLIQHNNRGIFKGLPKGFPAIRYHSLIVDKPTLPECLEITAWTDDG
TIMGLRHKEYPVEGIQFHPESFKTECGKEILGNFLKYYAPVSGKRE