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# Streptococcus pyogenes phage 5005.3

>M5005_Spy1425 phage protein
MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGYIYDGAT
FTTKTLKVKGRVTVSDVEGVLDKQDELNALLVVDEPFYVTKMYPENSDLF
NFELPGESTGDLQLIGSPHKPWKYRFKVILDDTIAYEFIGKTSQGLKYNL
SFTLRTAELPFGETKPKDITLSGGSFAYGGTAKASQLEWPFIIELTPSGG
QTNFYIEIDGRRFEFKQNSQLQNSDKLLLTGIATTLNGNYVNAKTNYEYF
IFNPNPNKRITYKTDFLGTIRILNFVELYK
>M5005_Spy0898 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MTKAVLTSISQLALKALLYEVSLSPKPGLVDRFDNGAHDDMSFITFIDSM
IALSPFFQAYIETGFAYAKEEPLLLFNRLRQLGQKAEETMFCATQGINTH
KGLNFSMALLLGATGAYLARTPHLMTDLGRFSKEDTLAICRLVKPMTAHL
IQTDLGHLNTKKEFTYGEQLFVTYGIKGPRGEASEGFTTLTDHALPYFRQ
MISQNDPETSQLRLLVYLMSIVEDGNLIHRGGIEAWKGVKADMRLLLQQD
LSTTDLRLALSSYNQCLINQHLSPGGAADLLALTFYFAFLEKLL
>M5005_Spy0934 lipoate-protein ligase A
MITIRDLASLPIFVYGDGNKKVPGALSPFVWTEVFLKTINQEPNQLILHI
WPMTRTVILGMLDRQLPYFELAKTEIGNNGYVPVTRNIGGLAVVADDGIL
NFSLVIPDHFSESISISNAYLIMVDVIRESFSDYYQRIEYHEIKNSYCPG
NFDLSIAGRKFAGIAQRRIKKGIVVSIYLSVCGDQAARGQLIKDFYEAGT
QGEVTKVNYPQIDPECMATLSELLETPFTVAEVLERLRLTLRQLGFSLTE
KSPDQALLTNFDAVYERMQLEVVRKEGK
>M5005_Spy1357 NH(3)-dependent NAD(+) synthetase
MTLQEEIIRQLGVKASIDPQEEIRKAVDFLKAYLRKHSFLKTYVLGISGG
QDSTLAGKLAQMAIAELREEASDQAYQFIAVRLPYGVQADEADAQKALAF
IAPDQTLTINIKAAVDGQVEALQAAGVEISDFNKGNIKARQRMISQYAIA
GQMAGAVIGTDHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLG
ADAALYEKVPTADLEDQKPGLADEVALGVTYQDIDDYLEGKLISKVAQAT
IEKWWHKGQHKRHLPITIFDDFWK
>M5005_Spy1267 phosphopantetheine adenylyltransferase
MLTKIGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKKSYFKLE
VRKAMLTQALADFTNVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEY
EENLEYFNHLLAPNIETVYLISRNKWQALSSSRVRELIHFQSSLEGLVPQ
SVIAQVEKMNEKT
>M5005_Spy0409 dephospho-CoA kinase
MSSLWTGYCQIKSWRKGDAHLSKMPEKKTMIIGITGGIASGKSTVVKVIR
KAGYQVIDADQVVHDLQEKGGRLYEALREAFGNQILKADGELDRTKLSEM
LFSNPDNMATSSAIQNQIIKEELAAKRDHLAQSQAIFFMDIPLLMELGYQ
DWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQLPIEEKKPYASL
VIDNSGDIAALIKQVQSALLLLANPR
>M5005_Spy1086 nicotinamide mononucleotide transporter
MAYLNYFTKTEWALWLSSVLAILISALLFGKQAPLALIASLIGVTSLIFS
AKANPIGQGLVIIFSIIYAYLSLRNSYYGELMTYLFMTLPMTIFSLFTWL
NHPFEGKKSQVTISRLTPTDRRCLFVFTILITLIFYSILASIQTAYLLVS
TLSIATSFSAVYLSYKRSPYFALAYGLNDLVLILLWMHAAQTDASQYAVV
ICFATFLINDSYTFYNWLMLQRYQEKKVKKG
>M5005_Spy0225 thiamin pyrophosphokinase
MSKVALFAGGDLSYISRDFDYFVGIDRGSLFLLENGLPLNMAVGDFDSVS
QKAFTDIKEKAELFITAHPEKNDTDTELALKEVFARFPEAEVTIFGAFGG
RMDHLLSNIFLPSDPGIAPFMAQIALRDQQNMITYRPAGQHLIHQEEGMT
YVAFMAEGEADLTITGAKFELTQDNFFKKKIYSSNAFIHQPITVSLPSGY
LIIIQSKDWS
>M5005_Spy1181 major tail protein
MNKNDTKNVTSAKPKTGGAIYSAPLGTELPKDAKSELNTKFKNLGYVSED
GVVNEDTRSSENIKAWGGDIVGAVQTEKEDKFTYKLIESLNVEVLKEVYG
AVNVTGDLSGGIQIKSNSKELEAHVIVVDMIMNGGILKRIVLPNAKVDEV
GEIKYVDGEVVGYETTLKCFPDKDGDTHREYIVKPGEANKKENSFEM
>M5005_Spy0819 hypothetical protein
MEERVLRSKKIIVTDNTLGGSKDYVGLVFLSRKKSNEDKSVVYFRTYLSV
W
>M5005_Spy1697 para-aminobenzoate synthetase component I/4-amino-4-deoxychorismate lyase
MHRKTIIDFKELGQRYLFDEPLVELVAKSLDQVGPVIEKVQHYQQLGYYV
VGYLSYEAAAFFDNALQTHNDRLGNEYLAYFTVHKTCQKKDLPLDYDSIT
IPNQWVSATQKEAYQKAIETIHREMQQGNTYQVNYTLQLTQELNAADSLA
IYNKLVVEQAAGYNAYIAHDEFAVISASPELFFKQEGNRLTTRPMKGTTK
RGVNSWLDQQEHDWLQADGKNRSENMMIVDLLRNDMGKICQTGSVRVDRL
CEVERYSTVWQMTSTIVGDLKADCDLIDILKALFPCGSITGAPKVSTMAI
ITSLEPKPRGIYCGSIGICLPDGRRFFNVPIRTIQLSHNQATYGVGGGIT
WQSKWEDEYEEVHQKTAFLYRHKQIFDLKTTAKVEHKKIAFLEQHLNRLK
EAATYFAYPYNEKALQKQLSTYLENKNNAAYRLMIRLSKDGKISLSDQPL
EPLSADFLTAQLSLQKKDVTASPFTYFKTSYRPHIEQKSYEQLFYNQAGQ
LLETSIGNLFVQLGQTLYTPPVAVGILPGLFRQELLATGQAQEKEVTLAD
LKEASAIFGGNAVRGLYPLNLELTHLDALLAKSQA
>M5005_Spy0264 hydrolase, HAD superfamily
MTYEDYLPYSRTELLAKIAEQMSPKRFKHVLGVEKAALSLAECYGCNPDK
AGLAALLHDYAKECPDQVFLDLIDKYQLSPELAKWNNNVWHGMVGIYKIQ
EDLGLKDKDILRAIEIHTVGAAEMTLLDKVLYVADYIEEGRIFPLVDDAR
KIAKLDLNQAVAYETVNTVAYLASKAQPIFPQTLDTYNAFCSYLKEY
>M5005_Spy0895 hypothetical membrane associated protein
MTYSFIDILQVTLVSLFLVLTCLTGIMGLMMLSGKLLSQEKKTLSQQASS
IPQEQEADKLSGEALETLLAKDELARIAVMTSLAYASQEESGKRFEVIAV
ERKS
>M5005_Spy0923 pyridoxine kinase
MKRIVVANDLVGVGKVALSASIPLMASCLLEQVLLPTCLLSSHTGGGQNP
VKHTTSSILDVFLTDWDNKRIKFDGIFIGYFTTTRDGQKLLEWLSRKQLP
LILDPIMADNGKLYQGFSQKHIEIMIKLTQKAELVLPNISEACLLTQTAY
LAKNYDEEDIRQVARKLAKLGPKQVVISGISFEEGSIGFAYYQSDSDQLT
FHFGKQFPYHFYGTGDIASAIITAGFYYQLPLTQILDLVVSFLEKVLQNT
LTLKRDLILGVAYESHLNYLTKSFKKLLEEKNVISKIS
>M5005_Spy1177 phage protein
MIPKVIIDDFDTSSIPNCVLTGYDVGDILSPSFVENEAYGMNGTSRELES
YNESKPTIMWHLSTFDDAVNLINHLDGLSKKIEFWHIPNSIYYYDCLSVK
INAVTMSSWRVTLKLALYPFRYAKGVSDVVIAGNGNINNAGNVFSEPKIV
VEGTGKGTLTIGKQVMELNLSGKATIECKHGQQCVYDAEGNVKNSIRIRG
SFFEIQPGTQGIAVSGGITRTIISPRWRYKV
>M5005_Spy0659 apbA, 2-dehydropantoate 2-reductase
MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEDHINAIKENGLVVTGDV
EETVKLPIMKPTEATQEADLIILFTKAMQLPQMLQDIKGIIGKETKVLCL
LNGLGHEDVIRQYIPEHNILMGVTVWTAGLEGPGRAHLQGVGALNLQSMD
PSNQEAGHQVADLLNEANLNATYDENVVPNIWRKACVNGTMNSTCALLDC
TIGELFASEDGLKMVKEIIHEFVIVGQAEGVELNEEEITQYVMDTSVKAA
HHYPSMHQDLVQNHRLTEIDFINGAVNTKGEKLGINTPYCRMITELVHAK
EAVLNIQ
>M5005_Spy0860 apbE, thiamine biosynthesis lipoprotein
MFVTQQLKLMGTVIDIQIESDKACQQLSRVIDLLYTYKNRFSANDSNSEL
MAINQAAGVKPVSVHSDLFNLIQIGKAHSLSTPSNLNIAIGPLVQAWRIG
FEDARVPSHNLISQQLALTDPRQVLIDDKKQTVFLQQVGMALDLGALAKG
YITDKIMAYLIEDGIDSALINLGGNVRVHGPNPKSPDKTFRIGIQKPDAK
RGQHLGVIKVNNHSVVTSGIYERQFTSKGKQYHHILDRQTGYPIETDMLS
LTIMAPSSFYCDIWTTRLFGLDSSMIITLLNTFDNIEGLLVTRKHHVLMS
NGLRHYFQPYYH
>M5005_Spy0713 bcaT, branched-chain amino acid aminotransferase
MTIAIDWDNLGFEYHKLPFRYISYYKNGQWDKGQLTEDATLHISESAPAL
HYGQQAFEGLKAYRTKDGSIQLFRPDRNAVRLQATADRLLMPQVSTEQFI
DAAKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPAEEYIFTIFA
MPVGNYFKGGLAPTNFIVSEAFDRAAPYGTGAAKVGGNYAGSLLPGKAAK
SAGFSDVIYLDPATHTKIEEVGAANFFGITANNEFVTPLSPSILPSITKY
SLLQLAEERLGMTVIEGDVPINELDKFVEAGACGTAAVISPIGGIQYKDN
LHVFYSETEVGPVTRRLYDELVGIQFGDIEAPEGWIVKVD
>M5005_Spy0908 citX, apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MVIRLLLLLNTVTVASWMWFTMCKDTYFSGEAIQLSDMLRAREERALRQL
HLLKEYPEGSLLSVTMNIPGPIKTSPKLLEAFDIVIKAIQTALADDKICY
QLRLLPTTGYEYYLITSLPSRDLKLKMIALETELPIGRLMDLDVLVLQND
LPHSISRTVLGGSPRQCFICSKEAKVCGRLRKHSVEEMQTAISKLLHSFF
NKDNQSSSSDKTG
>M5005_Spy0945 coaA, pantothenate kinase
MSNEFINFEKISRESWKTLHQKAKALLTQEELKSITSLNDNISINDVIDI
YLPLINLIQVYKIAQENLSFSKSLFLKKDIQLRPFIIGISGSVAVGKSTT
SRLLQLLLSRTHPNSQVELVTTDGFLYPNQFLIEQGLLNRKGFPESYNME
LLLDFLDSIKNGQTAFAPVYSHDIYDIIPNQKQSFNNPDFLIVEGINVFQ
NQQNNRLYMSDYFDFSIYIDADSSHIETWYIERFLSILKLAKRDPHNYYA
QYAQLPRSEAIAFARNVWKTVNLENLEKFIEPTRNRAELILHKSADHKID
EIYLKK
>M5005_Spy0890 ddh, D-lactate dehydrogenase
MKLKLYNVRGEEAVLAKKWADDNGIEISLTESPLTPETVKEAEGFDGIAN
AQIGPLDDAIYPLLKEMGIKQIAQHSASVDMYNLDLATENDIIITNVPSY
SPESIAEFTVTIVLNLIRHVELIRENVKKQNFTWGLPIRGRVLGDMTVAI
IGTGRIGLATAKIFKGFGCKVVGYDIYQSDAAKAVLDYKESVEEAIKDAD
LVSLHMPPTAENTHLFNSDLFKSFKKGAILMNMARGAVIETQDLLDALDA
GLLSGAGIDTYEFEGPYIPKNFEGQEITDSLFKALINHPKVIYTPHAAYY
TDEAVKNLVEGALNATVEIIKTGTTTTRVN
>M5005_Spy0936 dfp, phosphopantothenoylcysteine decarboxylase
MTKHITLAVSGSISAYKAADLTSQLTKIGYDVHIIMTQAATQFITPLTLQ
VLSKNAIHLDVMDEHDPKVINHIELAKRTDLFIVAPASANTIAHLAYGFA
DNLVTSVALALPATTPKLIAPAMNTKMYQNPITQENIKRLSTIGFTEIPP
KSSLLACGDKGPGALADIDVILATIDTIWKL
>M5005_Spy0935 dpfB, phosphopantothenate--cysteine ligase
MTMKLIITSGGTTEPIDAVRGITNHSTGQLGKLITERFLQYHHDVTLVTT
KTATKPLPNKRLRIIEVETVNDLMAALKDQVPHHDILIHSMAVSDYTPVY
MTDLEQVSQADNLNCFLCEHNSEPKISSASDYQVLFLKKTPKVISYVKQW
NPNIKLVGFKLLVNVPQEELIKVARASLAKNHADYILANDLVDIQTGMHK
ALLISNNEVASADTKEAIADLLYERMTKHD
>M5005_Spy0689 dyr, dihydrofolate reductase
MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAILMGRVTF
EGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYII
GGNKVLEAFNGYFDRVIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARD
AKNPYDFTVTALKHK
>M5005_Spy0324 fhuA, ferrichrome transport ATP-binding protein
MTTISAEDLTIAYEQRTIIDKLSFYIPEGKITTIIGANGCGKSSLLKALT
RLLPPKQGVVYLNGQNIATLETKEVAKKLALLPQVQEATNGITVYELVSY
GRFPHQSYFGNLSPADKKAIHWAMQATNVMAYADQPVDALSGGQRQRVWL
AMALAQGTDTIFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIVMVLHDL
NLSARYSDHLIAMKHGKIHYTGTIADVMTSPIIQDIFQIKPVLVDDPIHN
CPIVLTYQLQ
>M5005_Spy1526 fhuC, ferrichrome transport ATP-binding protein
MSKNSSHIQVQNLSFAYEEKLVLDDLTFSIPKGKITTIMGANGSGKSTLL
QLLTKNLPLKQGQVWLEQEELATISLKAFAKKVAVVHQYHQVVEGLLVGE
LVAMARLARRSFFKTTTKEDEERLAWALEVTALSDYVYRDIQHLSGGEQQ
RVWIAMALAQDTDIIFLDEPTTYLDIKYQLDILKLITKINQELGLTIVLV
LHDINQALSLSDHLIGLKDGRLYAQGQPRDLLDQQFIRDVFGVELPFVER
NGQQFVLTSLVNETNGIRTQRRDRNKNR
>M5005_Spy0820 folC.1, folylpolyglutamate synthase/dihydrofolate synthase
MTYEETLEWIHDHLVFGIKPGLKRMLWVLGQLGNPQKNVKGVHIVGTNGK
GSTVNHLQHIFTTAGYEVGTFTSPYIMDFKERISINGRMISEKDLVIAAN
RIRPLTERLVQETDFGEVTEFEVITLIMFLYFGDMHPVDIAIIEAGLGGL
YDSTNVFQAMVVVCPSIGLDHQAILGETYANIAAQKAGVLEGGETLVFAV
ENPSAREVFLTKAEQVGASIWEWQEQFQMAENASGYRFTSPLGVISDIHI
AMPGHHQVSNAALAIMTCLTLQDRYPRLTPDHIREGLANSLWLGRTELLA
PNLMIDGAHNNESVAALVAVLKNNYNDKKLHILFGAIDTKPIADMLVALE
QIGDLQVTSFHYPNAYPLEKYPERFGRVADFKDFLALRKHAKADDFFVIT
GSLYFISEIRQYWEKHIEKSVLLTH
>M5005_Spy0628 folC.2, folylpolyglutamate synthase/dihydrofolate synthase
MTTYDSISWIHTFKANGRKTDLARMAWLLEALGRPQDKFPAIHVVGTNGK
GSVTAYLQHILSTSGYQVGTFTSPFIISFHDRICLNGQPISDLELAQCVS
VIRPILTKMSLETNWDRPTEFELVTLIMFCYFANLKPVDIAIIEAGIGGK
TDATNVFHALAVVCPSISFDHQERLGYSLAEIAHQKAEVIKAKEPVIIGQ
LEQEASQVFQQVTQKAGSRLYQLGKDFLLNPSEKTFSFQHDNLNLTKLRL
KLLGQHQKANACLAIMTAQLLRKSFPKISPKTIQKGIEATTWPGRSEFIQ
PNLLLDGAHNPDSIAKLKSLLQEEFPKRPIHILFAGLKRKPLADLLAQLD
TFEVSVTTFDFPEANLLEDYPDKYPQVKDYRDWLQGSVTSDELFVVTGSL
YFISEVRQYCLSNANIFKNIFP
>M5005_Spy1234 folD, methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase
MTELIDGKALAQKMQQELAAKVNNLKQKKGIVPGLAVILVGDDPASQVYV
RNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQLPL
PNHINDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMELLR
EYNVNLEGKHAVIIGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEVCR
CADVLIVAIGQGHFITKQYIKDGAIVIDVGMNRDDNGKLIGDVAFDEVAE
VAAKITPVPGGVGPMTIAMLLEQTYQSALRSTHK
>M5005_Spy0821 folE, GTP cyclohydrolase I
MSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVAKMYAEMFLGLGKDP
KEEFTAVFKEQHEDVVIVKDISFYSICEHHLVPFYGKAHIAYLPSDGRVT
GLSKLARAVEVASKRPQLQERLTSQIADALVEALNPKGTLVMVEAEHMCM
TMRGIKKPGSKTITTTARGLYKESRAERQEVISLMTKD
>M5005_Spy0824 folK, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase
MTIVYLSLGTNMGDRAAYLQKALEALADLPQTRLLAQSSIYETTAWGKTG
QADFLNMACQLDTQLTAADFLKETQAIEQSLGRVRHEKWGSRTIDIDILL
FGEEVYDTKELKVPHPYMTERAFVLIPLLELQPDLKLPPNHKFLRDYLAA
LDQSDITLFSAQQTEF
>M5005_Spy0822 folP, dihydropteroate synthase
MKIGKFVIEGNAAIMGILNVTPDSFSDGGSYTTVQKALDHVEQMIADGAK
IIDVGGESTRPGCQFVSATDEIDRVVPVIKAIKENYDILISIDTYKTETA
RAALEAGADILNDVWAGLYDGQMFALAAEYDAPIILMHNQDEEVYQEVTQ
DVCDFLGNRAQAALDAGVPKNNIWVDPGFGFAKSVQQNTELLKGLDRVCQ
LGYPVLFGISRKRVVDALLGGNTKAKERDGATAALSAYALGKGCQIVRVH
DVKANQDIVAVLSQLM
>M5005_Spy0823 folQ, dihydroneopterin aldolase
MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLSDQLTDT
VHYGMVFDSVRQLVEGEKFILIERLAGAICEQLFNEFPPIEAIKVAIKKE
NPPIAGHYKAVGIELERQR
>M5005_Spy1231 fps, dimethylallyltransferase/geranyltranstransferase
MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPLILLEMI
EGFGVSLQNAHFDLAAALEMIHTGSLIHDDLPAMDNDDYRRGRLTNHKQF
GEATAILAGDSLFLDPFGLIAQAELNSEVKVALIQELSLASGTFGMVGGQ
MLDMKGENQALSLPQLSLIHLNKTGKLLAFPFKAAALITEQAMTVRQQLE
QAGMLIGHAFQIRDDILDVTASFEDLGKTPKKDLFAEKATYPSLLGLEAS
YQLLTESLDQALTIFQTLESDVGFKPQIITKLIEGLRLNA
>M5005_Spy0765 hemN, coproporphyrinogen oxidase
MKNQGKWFIHRNILSSKWYNKTMSKKPTSAYVHIPFCTQICYYCDFSKVF
IQNQPVDAYLKALIQEFDSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHL
ERNLNLDDLEEFTIEANPGDLTPEKIAVLQRSAVNRISLGVQTFNNKQLK
QIGRSHNEEQIYSTIANLKTAGFHNISIDLIYALPGQTLDQVKENVAKAL
ALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEMFEYIISEMEA
NGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRV
PIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKF
GMSFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
>M5005_Spy0928 lplA, lipoate-protein ligase A
MYLIEPIRNGKRITDGAVALAMQVYVQENLFLDDDILFPYYCDPKVEIGK
FQNAVVETNQEYLKEHHIPVVRRDTGGGAVYVDSGAVNICYLINDNGIFG
DFKRTYQPAIEALHHLGATEVEMSGRNDLVIDGKKVSGAAMTIANGRVYG
GYSLLLDVDFEAMEKALKPNRKKIESKGIRSVRSRVGNIREHLAPQYQGI
TIEEFKDLMVCQLLQIETISQAKRYDLTEKDWQQIDALTERKYHNWEWNY
GNAPQYRYHRDGRFTGGTVDIHLDIKKGYIAACRIYGDFFGKADIAELEG
HLIGTRMEKEDVLATLNAIDLAPYLGAITAEELGDLIFS
>M5005_Spy0758 lplB, lipoate-protein ligase A
MKYIVNKSHNPAFNIALEAYAFRELVEEDELFILWINEPAIIIGKHQNTI
QEINKEYIDEHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTAEGAFDFKT
FSQPVIATLADLGVTANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLL
FDVDMTVLGDALKVSKDKIESKGVKSVRARVTNILNELPEKITVEEFSDK
ILAKMKETYPDMTEYVLSEDELAKIEQSAKEQFGSWDWTYGKAPEYTIER
NVRYPAGKISTFANVENSIIKNLKIYGDFFGIKDVQDIENLLIGCKYEYR
DVFERLKTIDTTQYFSRMTVEEVAKAIVS
>M5005_Spy1108 metK2, S-adenosylmethionine synthetase
MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAETCVYTG
SVHVFGEISTTAYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQ
SGDIAQGVNEAFESREGDTDDLSHIGAGDQGLMFGFAINETPELMPLPIS
LSHQLVRRLAELRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQ
HDPEATNDQIRQDVIEKVIKAVIPADYLDDDTKFFINPTGRFVIGGPQGD
SGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNLVAA
GLVTKAEVQLAYAIGVAQPVSVRVDTFGTSTVPEAVLEAAVRQVFDLRPA
GIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWERLNKVDALVEAVKTVL
>M5005_Spy0960 mreA, riboflavin kinase/FMN adenylyltransferase
MEIEYIKDYRDINQEDDTVLILGYFDGLHRGHKALFDKAREVANKEGLKV
VVFTFTESPKLAFSRFSPELLLHITYPKKRYEKFADYGVNKLYLVDFTSK
FSKVSSDHFITHYIKNLKAKHIVVGFDYKFGHNRTDSDYLTRNFEGQVYT
IEEIKEDHRKISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGR
TIGFPTANLAPIDNTYLPADGVYVTNVIVANKIYRSMTSLGKNVTFGGKE
LRLEVNIFDFDEEIYGEIIEIVWLDKIRDMEKFEGIEDLTDRLEYDKRTA
LNWKKDSKLS
>M5005_Spy0170 nadC, nicotinate-nucleotide pyrophosphorylase (carboxylating)
MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKVSLFAKE
AGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRS
LLTCERVALNFLQHLSGIASMTAAYVEALGDDRIKVFDTRKTTPNLRLFE
KYAVRVGGGYNHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMV
EVEVESLAAAEEAAAAGVDIIMLDNMSLEQIEQAITLIAGRSRIECSGNI
DMTTISRFRGLAIDYVSSGSLTHSAKSLDFSMKGLTYLDV
>M5005_Spy0263 nadD, nicotinate-nucleotide adenylyltransferase
MALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVADQVRQQ
LGLDQVLLMPECKPPHVDAKETIDEKHRLRMLELAIEDVEGLAIETCELE
RQGISYTYDTMLYLTEQHPDVDFYFIIGADMVDYLPKWHRIDELVKLVQF
VGVQRPKYKAGTSYPVIWVDLPLIDISSSMIRDFIKKGRQPNYLLPKRVL
DYITQEGLYQ
>M5005_Spy1358 nadE, nicotinate phosphoribosyltransferase
MYKDDSLTLHTDLYQINMMQVYFEQGIHNRHAVFEVYFRKEPFNNGYAVF
AGLQRMVEYLEQFQFSETDLAYLEELGYPENFLTYLKELRLELTIRSAKE
GDLVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIED
EPLLEFGTRRAQELDAAIWGTRAAMIGGADATSNVRAGKRFDIPVSGTHA
HALVQAYGNDYDAFMAYAKTHKDCVFLVDTYDTLKVGVPTAIRVAKEMGD
KINFLGVRLDSGDLAYLSKTVRQQLDDAGFTEAKIYASNDLDENTILNLK
MQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIEQEDGSMRDTIKLSNNA
EKVSTPGKKQVWRITSREKGKSEGDYITFTDINVNELTEIEMFHPTYTYI
KKTVKEFDAIPLLVDIFVKGELVYQLPTLAEIKAYAKKEFDKLWDEYKRV
LNPQDYPVDLARDVWQNKMALIDNIRKDAYGKSE
>M5005_Spy1616 thiD, phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase
MKTDYIVTISGNDILSGGGLYADLATYIRYDLQAFVAVTCLTTRSEEGFS
LFPVAKEIFRDQLNSFTNAPISAIKIGLLPNAEMCEIVLDFIKGHLGIPV
VLDPVLACKEIDDVKIVPLRQEILQLLPYVTVVTPNLVEAQLLSQKEIVS
LKDMQEAAKYFYQLGAKQVVIKGGNRFSQKKAIDLFYDGKEIVTLECPVL
EKNNIGAGCTFASSIASQLVKKKTPLEAVKNSKELVYQAILQSDRYGVKQ
SYAK
>M5005_Spy0631 thiI, thiamine biosynthesis protein
MDYSEIMVRHGELSTKGKNRMRFINKLKNNIQDVLAPFPAITVRSDRDRT
HVSLNGTDYQPIVEALKLVFGVQALSPVYKLEKSVPLLVTAVQDIMTSLY
RDGLTFKIATKRSDHAFELDSRELNSLLGGAVFEVLPNIQAQMKHPDVTL
KVEIRDEAAYISYEEIKGTGGLPVGTSGKGMLMLSGGIDSPVAGYLALKR
GLDIEVVHFASPPYTSPGALAKAQDLTRRLTRFGGNIQFIEVPFTEIQEE
IKNKAPEAYLMTLTRRFMMRITDAIREQRKGLVIVNGESLGQVASQTLES
MQAINAVTSTPIIRPVVTMDKLEIIEMAQAIDTFDISIQPFEDCCTIFAP
DRPKTNPKLGNAEKYEERFDIDGLVQRAVSGIVVTEITPEIVNDEVENLI
DALL
>M5005_Spy1698 trpG, anthranilate synthase component II/para-aminobenzoate synthase glutamine amidotransferase component II
MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKANALVLSPG
PGWPKEANQMPKLIQDFYQTKPILGVCLGHQAIAETLGGTLRLAKRVMHG
RQSTIETQGPASLFRSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEI
MAFEHHTLPLFGLQFHPESIGTPDGMTMIANFIAAIPR