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# Synechococcus sp. WH 8102, WH8102

>SYNW0875 conserved hypothetical protein
MTAATDGALPPWRQRLRGALKREGRQVSARWLQLATVASDGTPRVRTLVF
RGWNGADQLELYTDGRSSKIAEFNHQPQVELCWLLTKAKQQYRLRGTAAQ
VAVSPDQAQWRSLSPSGRALWGWPHPGQPFEPAAPFPQELPEDAPVPDHF
VMVPISLQQVELLDLSHHPHQRLLWRRENGWLEQRLNP
>SYNW1605 DUF170
MALKLTVNGEVRCLDPEPMPPTLEAVIAALGHNPQLVVAEHNGVIAPRGG
WASTTVGEGDSLEIVTIVGGGS
>SYNW0714 conserved hypothetical protein
MTTKQDCRGHFRERRQQQISLGSAIYRQVLTMVQRSPLRPGYLGLYWPLS
SEVDLRPIRAITPNAVALPVADGSGGLQYRCWGDTPLQADGCGIPAPTNA
PALSPDKLSLLLVPALAIDHSGIRLGYGGGYYDRLRADPLWAAVPAWVVL
PSACISSEPLPRDTWDVPFTGWITEHGPGQPS
>SYNW2197 conserved hypothetical protein
MVKTPEAPASLTVAIDALDERLSQRFIALDPSGYFLIKVDADAGELVLEH
YGNTIDEKGLARDSDTGEVLSCKGGNGLRQPSRIYRGSSAKQVGIQLTEG
DGPHPLSRLDHALYLGRELQKAEQCLLNGSAYVQD
>SYNW1006 Protein of unknown function DUF117, putative carboxy-lyase
MALFRSGPATRDLRGFLQLLDQRGQLKRITAAVDPDLELAAIADRVLSQG
GPALLFENVIGSSMPVAVNTLGTVERVVWSMGLERAEQLEDLGSRLALLQ
QPRPPKGLSETKQFARVFWDLVKAKPDRDLTPPCRQQIFKGDAVNLYNIP
LIRPWPGDAGGVITLGLVITKDPETGVPNVGVYRLQRQSVNTMTVHWLSV
RGGARHLRKAAAMGKKLEVAVAIGVHPLLVMAAATPIPVQLSEWLFAGIY
AGEGVRLTPCKTLDLQVPSHSEVVLEGTITPGEVLPDGPFGDHMGFYGGV
EDSPLVRFHCMTQRRDPVFLTTFSGRPPKEEAMLAIALNRIYTPILRQQI
PEITDFFLPMEALSYKLAVISIDKAYPGQAKRAAMAFWSALPQFTYTKFV
VVVDKHINVRDPRQVVWAIAAQVDPQRDLFTLADTPFDSLDFASEQLGLG
GRLAIDATTKVGPEKNHDWGEPLSRPADLEERVSARWSELGLDGLGQDEP
DPSLFGYALDRLIQGLKTSP
>SYNW0277 cob(I)alamin adenosyltransferase
MTASLTSSHRSSDSVAQDHRALERAGLRPLVPVRPPLQLVEPEGQLQVHT
ATYRGSFSSVLSQAMRTAGLGSRVLIAQFLKGGVHQGPQGCVRLCGGLTW
LRPDVPACLSQADHPGGAAAVDAVWQSCRRHLRDGDIDQLVLDEVGLAVG
LGYVEEGALLDALDQRPPAMDVVITGPAIPPSIVAMADQVTQLRRGF
>SYNW2161 putative 4'-phosphopantetheinyl transferase
MEPPLLGSRSVTALWLIPEHQDLPSDVELSPVEAGWMDGMAMSRAVAFRR
SRLWMRRCLADCFEVDPATVPLQAPPGEPPTLADGWGCLSLSHCCDAVLV
AWSPDAVGVDLERCDRCFPAAALADRFYCAEDRRELDGLAGETLRMAVLK
QWVAKEALIKMQRGSLALDLSRWRCGADACQGLHPDLEHPVPVHRLQLEG
WLMAVAGAAGQVGPICLA
>SYNW0465 conserved hypothetical protein
MQVADLLELRDDLSRECSGLHKLVTGLRKLSQRLDHSADAVEAAALRLHS
FYIGVERMLLLISRVVNGGTPSQWEGWHRRLLEHMAMATDIRQAVLNEST
QQELQQHLRFRHLVLNLYADELRPKPIQRLIEQLQHTWPKLQADITGFQR
WLRSIASESI
>SYNW0991 conserved hypothetical protein
MFSGWTSMQRDRQPEVMDQPGLDPAEHDRALQGLRRINGISRCVPGLFRH
VEALAGESPATQLSVLELACGGGDTAIELAALARGRDLDVLVQACDLNPE
AVRLARRNVARSDSNVGVFVADALDPSESKQFDVVYCTLFVHHLDPPDVV
RLLKGMTARARRLVIVDDLIRSRLGYSLAWMGTRLLSRSWVVHHDGPLSV
KGAFTPSEILDLASQAGLHDCVLERTWPERYRLCWRPH
>SYNW0503 Putative nicotinate-nucleotide adenylyltransferase
MQKIALLGTSADPPTCGHQALLKGLLSLYPQVATWASDNPQKHHGAPLAL
RAQLLQALVEEINDPRLQQEQTLSHPFTIRTIEQATARWPEAELVFVVGS
DLAALIPGWKSSAQWLSRCRLAIAPRQGWPLRDQALADLKRLGARIDLLE
LQVPASASSALRQSPEQRQIPAAVWTLLLEHNLYGLFPSLR
>SYNW0040 conserved hypothetical protein
MLRSTAQRILCSAGVIVGLLCGSSTAWAGTDTEEKGAQVYCFMRSSGNAH
DVSWNAAYALIKRQSRGLFKTSPEHASVMITEAVVKDPGTFPDCGQFLGD
LFGGATTATAASLGSTSTPTQTNTSFSSDGYAASEAERYSY
>SYNW1162 hypothetical
MKEKILSFIRQKSLEHSIDSDEDSKYHIEFTTTPACGVRCKYCPQETLRK
SSLKFKNINNKSITLDNFKCYLKNFHDYPTLNIHWTGYSEPCANKDFSAM
AQHCADLKLEQQISTTLTGFPYNIDFIANNPSFFKSIGLHLPDDAGLMED
GVLQVDDSYLTTLARFLDDFERSSHNGVELRALTFGPSFHPQIEEILANK
SHLFAGMSRHRKLSSRSSGVDSLYFRKLWKYKSKSQVATLIKQSLKRIYV
FFRPIILLEIPLPAKKCIVKKFGSQPVVLGNGNVNICCHDYSLSQVICNV
NNENFRASLRKWRESVLNDFSSGELSPCKKCEFYQPLTFKDLLPKR
>SYNW2433 Aminotransferase class IV
MTGGVAWCEGRWGTPAELSLPLDDRGLQLADGLFETVLIRAGQPCLLDEH
LQRWGEASALLGLDPPPERDHLMPLIQEAVERALPEQGCGALRLNWSRGS
SPQRGIAPPRSGEHRFWLTLQPWVPSFTPITAIISRLERRNCDSLLSRCK
TFAYGQAVQARREASEQRCDDALLLNTNGELCCSTTANLLLKPGSANGNS
PWLTPPLSSGCLPGVMRARALRLGLAVEANLGASLGSDDQLLLINSLGCR
GLLSLDHQPLHSQALGIDPAESLWQKLLS
>SYNW1708 conserved hypothetical protein
MDQWQERKRPVCLERRFEFDGYSSTRDFLDKLGEHSESTQRFPDISFGST
YVNITIRPEDDNPDAQLNEADRAFAAQIDALLG
>SYNW1139 hypothetical
MRKKSHGLETRTQPRAVSGPLPLAGVSFCVGTPSPAIAHLLSACSNSYKT
FTPLSGGADTPSHGTGTWNYLRNYPMTALLYRGRPYTTPQASPKSCVELT
YRRGHYNTCREEVARNVHQSLTYRGATYNK
>SYNW2200 putative riboflavin-specific deaminase
MQGERPTVRLVLAISLDGRLAPAEGGAAQLGGDGDRIALEQALAWADACL
IGAGTLRAHQCTCLIRNQTLVDQRLAAGRPAQPAAVVASRSGNVSSSWRF
FQQPLQRWLLAPAPMEWGFERWFPLAESWTEQLVGLGSAGIQRLVLLGGA
HLAADLLAGDCVDELQLTVVPRVLGGGNTWLPTTSPGLPYALSQAEAWRA
VGAEPLGSGEWLLRYRRLRESAE
>SYNW1007 probable 2-phosphosulfolactate phosphatase
MQIFYFHVPAEMPADASPDAAVVIDVLRATTTIAWALHHGAEAVQAFADL
EDLRAAAEAWPADQRLLLGERGGQTLAGFDLGNSPVAVVPATVSGKRLFM
STTNGTRALDRVRQVPLLVTAALPNREAVAQRLLKESPETVAIVGSGWEG
TYSLEDSLAAGALAARLQELSQAVTLANDEATAATALWQQWRHDPEACLR
TASHGQRLIRLGDHDDDFRCCAGLDQLSVVPTQQSPGVLQAI
>SYNW1731 Biotin/lipoate A/B protein ligase family
MPTARSPGRLIPNRIADGPTQMAIDALLLAQATEVPVLRFYRWDGPWLSL
GRHQRHWPQHWEQLAREGRLRMVRRPSGGQAVLHAGGLTYALIWPSAPRR
RKQAYREACQWLIDGFSQLGLPLQFGDDPALGSGNNCFASSTAADLVDRA
GVKRIGSAQCWQHGRLLQHGEILLDPPPTLWQAVFGEAAPPAAAAKLNRL
TLDQQLINAMAMAWPDVAWEEMPLSDDEHAQVEGRLRSVCSEFAGIDATI
>SYNW2201 6-pyruvoyl-tetrahydropterin synthase homolog
MTEMKSPPRHGQGRGCVITRRACFSASHRYWLPELSADDNAARFGPCAIA
PGHGHNYELIVSMAGGLDADGMVLNLSEVKHAIRQEVTGQLDFRFLNEAW
PEFDVSGPSGCLPTTEALVRVIWQRLSPHLPITALRLYEQPGLWADYLGH
PMDAFLTIRTHFAAAHRLARPELSQEENEAIYGKCARPHGHGHNYLVDVT
VRGAIDPRTGMVCDLSALQRLVDDLVVEPFDHTFLNKDVAFFAECVPTAE
NIALHIADRLSTPVKAIGAHLHKIRLQESPNNAAEVYAETPQLDRMPAAL
ESVAAV
>SYNW2052 conserved hypothetical protein
MPRSIGIVTAADSRERSHGQLHIYDGEGKGKSQAALGVVLRTIGLGICEQ
RRTRVLLLRFLKGPGRAYDEDAAIEALQQGFPHLIDHLRTGRADHFTAEE
ATRFDREEAQRGWVIAKGAIASALYSVVVLDELNPVLDLGLLDVEDVVNT
LRQRPEGMEIIVTGRAAPAPLVRVADLHSEMRAHRRPGLEEERVIPLNMS
SGIEIYTGEGKGKSTSALGKALQAIGRGISQDKSHRVLILQWLKGGSGYT
EDAAIAALRDSYPHLVDHLRSGRDAIVWRGQQEPIDYVEAERAWEIARAA
ISSGLYKTVILDELNPTVDLELLPEEPIMQTLLRKPTETEVIITGRCKNQ
PAYFDLASIHSEMVCHKHYAEQGVDLKRGVDY
>SYNW2432 possible p-aminobenzoate synthetase
MSVPQRLDLPWREPLAVARQLDGDDGLIWLDGDGSDLGRWVTLASQPLEV
IHCQGLPGDADARDPFTALNGLGPGHWTGWLSYEAAAWTEPGNPWSRDAM
ANLWIARHDPLLRFDLQQRQLWIEGTDPMAMQQLAARLQQRAPTPPATAN
IPLEAWHQHTSREGFADGVRRIRALIAAGDLFQANLTACCSTDWPGDASA
VELFQRVRQRCPAPFAGLVVADNGEALLSSSPERFLQVDPAGRVETRPIK
GTRPRHSDPDRDAELAAELVCSDKDRAENVMIVDLLRNDLGRVCQPGSIQ
VSQLLGLESYSSVHHLTSVVEGQLQAGLSWVDLLRACWPGGSISGAPKLR
ACQRLQELEPTSRGPYCGSLIRIDWDGRFDSNILIRTLMRKDHRLRAHAG
CGIVADSDPDGEAEELMWKLRPLLEALA
>SYNW1504 conserved hypothetical protein
MPDPPTRFTCSKQFEGYPCCHRQWRHAGHCRFVHGYSRSFTLWFAATELD
ECGFVVDFSSLRPLEQQLREQFDHTFLVNADDPLLEDWRRLHEQGALDLR
VMDNVGMESTAALVWDWANSLLKQRDGGRSCCWAVEARENSRNAAQVHAV
PSWFEAAG
>SYNW1794 4a-hydroxytetrahydrobiopterin dehydratase (PCD)
MIAMPTLLSADQRQTLPATLPHWTVHEQSISRELVFNDFNEAFGFMSRVA
LLAEGRNHHPNWSNVYNRVSITLSTHDLGGLSDLDVELAAAIDQLLPA
>SYNW0887 possible oxidase
METKTRKAATAHKIIEAGEGVLNLVWGKADERRAASLEIIARTAYTAEES
ACHYLETIGLDKEGTIRDTLELARYQDTNEQTHEDIFARDLDGLKNWGDR
FLARHIAVVIYWVFAITTLIDHEMAALLGEAVEVEAVKTYRRMLKEQPEE
WLDQPAAPTATHYWEKPNSMWRVRGDHMPGSMRDVVEAIVRDEADHVKAN
SKKATAF
>SYNW1776 conserved hypothetical protein
MQGRGIGQGRIWLLSGTGEGPPLAAALLRIGWRVEVSVVTPSAARPYAGL
DLDWMAVGSLQGEKAIEAVLKNGAGFRWVIDATHPFAVRISADLARTCAR
CGQPLLRLQRPLEQGGAVQLLDRFGDLRGFDLGGRRLLLALGGRHLPAVH
SDAVAAGAEVFARCLPSADGLKAALAAGLLPDHLAVVRPLQGGRAGAIER
ALCRRWGITDVICRQSGGVTERLWRQLSANLDMRLLMLRRPASPTGVETV
ESEASLMKRLQEAPRRGADD
>SYNW1674 possible menaquinone biosynthesis methyltransferase
MKPGDPAAVEQLFDSVASRYDQLNDLLSLGLHRQWKRQLQCLLRPAAGET
WLDLCCGTGDLALELARRVRPGGSVLGLDAAAAPLELARHRQSRQPWLNV
VFQQGDALSTGLPDASADGIVMAYGLRNLADPVVGLKEMARLLKPGRLAG
VLDFNRLTTAGPAADFQRFYLRRLVVPVASAAGLKEEYAYLEESLKRFPD
GTAQERLALEAGFAEARHHTLVAGQMGMLLLKR
>SYNW1869 conserved hypothetical protein
MLPLTLSDLEGLPLGCSIVGSRCSRQQLQAHLEPWCQGDSSFDLLLLLAA
TRTAEREGISAAGATAASRRLTALADADLLLHGPGKPRRWPLPPLPAGVS
PALLSHVALQRLPMQPLVAALGLEHEATFPHLRLESPQAGPARCLSTGRA
MDPERVERLWRKGMRLGAQLRRPLLLAECVPGGTTTAQAVLKALGVPVNG
LISGSARQPPQELKRHLVEQGLCRAQLPAWPSPQAVLAAVGDPFQAVAAG
VLVSAQQPVLLGGGSQMAAVATLALASLPDQERKVLADRVLLGSTAWLAL
EWIRGGDMPALGCLLDEVGHRFGVSLAGLASGLRFHASRQPALRDYEDGF
VKEGVGAGALLLLAQLQGQHSEALVEGCERALDQLLASAVASEV
>SYNW2287 Possible magnesium protoprophyrin IX methyltransferase
MAPDQLLEQKQAEKQEVKGYFETTGFDRWNRIYSESDDVNKVQRNIRIGH
QKTVDEVLAWIKDSGELNEVSFCDAGCGVGSLSLPLAEMGAGSISASDIS
EAMAQEADRRARAAGLDMGKLNFFASDLESLSGSFHTVCCLDVFIHYPQQ
PAEEMVKHLCSLTEERLIVSFAPYTLLLALLKGIGQLFPGPSKTTRAYTL
KEEGIVKSAEACGFKLVRRSLNKAPFYFSRLIEFRKA
>SYNW0629 BioA, putative diaminopelargonic acid synthase
MTKDAQAAMRTTADQSRHPNLWPPFTQIESAPLPQRVIAGDGALLLREQG
IPLIDAISSWWVTLHGHGHPVMAKAIADQAARLEQVIFADFTHEPAERLG
ERLSKLTGLDRLFFSDNGSTAVEVALKIACQWWVNRGEPRHQIVAFDGAY
HGDTFGAMAVGERNLFSEPFDDKLFPVARCPWPATWWDDPDVDAREQAAL
AVLETTLQQPTAAVILEPLLQGAGGMAMVRGTFLRQVEMLVRQAGALLIA
DEVLTGFGRCGDWFACHRAGIQPDLMALSKGLTGGCLPMGVTMASERVFS
AFVGADPSLTLWHGHSFTANPLGCAAANASLDLLQQDPDQFRGFEARHRP
HLEQLRAHPNVTRCRLTGTVAAFDLSVSGDAGYLNPAGPTIKRIALEHGV
FLRPLGQVVYLLPPLCISNDQLGQCYKAIATALDQI
>SYNW0933 BioB, biotin synthase
MTFTIRHDWTIAEIQALLELPLMELLWQAQYVHRAANPGYRVQLASLLSV
KTGGCEEDCAYCSQSIHNSSDVTAFEAQMQVEPVLQRARAAKEAGADRFC
MGWAWREIRDGAPFEAMLSMVRGVRDLGMEACVTAGMLSDQQAERLAEAG
LTAYNHNLDTSPEHYDRIISTRTYQERLETLQRVRKAGVTLCCGGIIGMG
ETLRDRASMLQVLASMAPHPESVPVNGLVAVEGTPLEDQAPFEPLELVRM
VATARILMPRARVRLSAGRESMSREAQILCLQAGADSIFYGDTLLTTGNP
DVEADRQLLADAGVQANWQECQTTA
>SYNW0631 BioD, putative Dethiobiotin synthase
MNHPSPQIVVCGTDTDVGKTVVSAWLVQGLNAHYWKPVQSGLEDGGDRGR
VQSLLNLPPDRMLPEAYAFHQPVSPHWAAELDGIPLNPDDLVVPHCTAPL
VVETAGGLMVPLTRRWLQIDQLQRWDRPIVLVARSGLGTLNHTLLSLEAL
NRRQLTVLGLILNGPAHADNPGTLEQFGGVPVLAHLPTLSPLTAESLARE
WQHQGLSSKFQDLLAIQQQ
>SYNW1876 BirA, putative Biotin--acetyl-CoA-carboxylase ligase
MTWTARPHRCGGRQLALHDRRFRTDRLGTWNLRWLPVCSSTEISLAEWLQ
DEPNLVRPRAVVARRQRRGVGQRGRHWQSPTGGVWLSAAMPWPGQSVTAA
GLLGLAVALELSNRLERQGVPVRIKWPNDLLVEGRKLAGVLPRLVHRGPQ
LRLVRCGIGLNVMNTVPIGAIALRELLPRSDASVEIWVGELLLSLERSLQ
LLAGSSAWLQLVEDRLWSDQVSSSDDGPSWTIDGLSPSGGLLLRRGQQRT
EWIRWP
>SYNW1240 CobN, cobalamin biosynthetic protein CobN
MHRLASCPGIDPPEDLVLVEQPPADVLLLSSAGTDLSCLEAVVQASPDWN
SRIRALHLDNLSHPAQLDHYLASTATQARLIVVRLLGSRGHWSYGLEQLQ
RWSEEVADRQLLVLAGTVDQQGDLRGIGTVVPALADRLAALLREGGETNM
ARLLDAIQALLDGTPPDSEEIEVAPLADPFPWDWQDDPGATVGVVLYRAQ
LQAGDTALAQHLNQALRERGLRPRLIWVSSLRDPAVQAGVLDLLRSQGAQ
VVISGTAFASVTTEQAGLGSALWDSLDRPVLQLLTAGTSRERWQQSSRGL
EPLDLSLQVVMPELDARVTTRPCAFRQARPPLSGLATAITTQQPDRDGIN
WLVEHAACWIDLQDTPAKHRRMAMVLANYPVRDGRVANGVGLDTPASVVN
IIGWLADAGYQLGEHPIPSNGDRLIASLLAGRTNSAEGRYRPPLDHLPLE
TYQAWWDTIPSEAKARIVSRWGEPQQACDLDGERGFAIHGLRYGHLVVLL
QPDRGYDPDQIADLHSPDLPPPHRYLAQYLWLREVHGSQVMVHVGKHGSA
EWLPGKGVGLSAACGPNLALGALPHLYPFIVNDPGEGSQAKRRGHAVVLD
HLTPPLGRAGLHGGLQKLEGLLDELVEARQLGGERTQVLETQVLSTLQDL
DWPEIPSRRELKKNPDRLNSCLDQAETYLCELKESQIRTGLHRYGQCPDD
AAMTELLMALARPPLQGQPGLTQLMAREAGLEFDPWSQDDGESLDPADRA
RLAALGCQRCRRVGDGSAWLEQQGLLILRQLVLHEQAVDLATPFRSLVET
SAPLRQRCLELWKRLQACDEAERQGLMRGLEGRRIAAGPSGAPSRGRPDV
LPTGRNFYSVDLRGLPTEAAWDLGRRSAERLLDLHLQDEGEPLRHLALSV
WGTATMRNGGEDIAQLLALIGVRPVWDGPSRRLVDLEVIPADLLGRPRVD
VVLRISGLFRDAFPQLVSWVNQAQQMVALLEEPEEINPLASLTRRDGPQG
RIYGSAPGAYGAGLQALIDSGAWESRRDLGEAFLCWSQWRYDGSAEPVAD
RSGLEQALSSVQVVLHNQDNREHDLLDSDDYYQFHGGLSAAAEQVSGQRP
QLWFGDHSRRERPRLHRLEKELDKVMRSRMLNPRWIEGMQQHGYKGAFEM
GASLDYLFAYDAATDRVPDWCYGAVCDRWLADPVNQTFLSDRNPWVLRDM
SERLLEASNRGLWTGARESQLALLKELISSSEARIERGALTC
>SYNW0245 CobS, Cobalamin-5-phosphate synthase CobS
MRPGPCNRPIARSVSPWLSDLAGAWIFYSVLPAWPWPSPRFQRIARFASW
IGLVIGAIQALLCWGLLRLGWTMSAAAPMVIALGIWLSGGLHHDGVMDTA
DGLAAGPERCLEAMEDSRVGASGVLALVMVLMLQLGALVQLGSAAPAALV
TVGVWSRVAPLWAMARFPYLRRDGTAGFHRRHGRPRWDALPSGVVLLVLC
IVLNPVMLLAGAPVALVVAEGLGRRLGGHTGDSYGAVLVLTETFTLVLLA
LTR
>SYNW1292 Dxs, 1-deoxy-D-xylulose 5-phosphate synthase
MHLGDLTHPNELHGLKLSELEDVARQIRDRHLQVVSTSGGHLGPGLGVVE
LTLALYQTLDLDRDRVIWDVGHQAYPHKLITGRFNDFHTLRQQNGVAGYL
KRSESNFDHFGAGHASTSISAALGMAMARDNRGEDFKCVAVIGDGALTGG
MALEAINHAGHLPETPLLVVLNDNDMSISPPVGALSNVLNRARLSPPMQF
LSGSVEESVRHLPFMGGELPAELNRLKGSMRRLAVPKVGAVFEELGFTYM
GPIDGHDIGEMMRTFQAAHRDGGPVLVHVVTKKGKGYPYAEADQVGYHAQ
SAFDLTTGKAIPSKKPKPASYSKVFGQTLVKLCEQNSRVVGITAAMATGT
GLDLLQKAVPNQYVDVGIAEQHAVTLAAGMACEGLRPVVAIYSTFLQRAY
DQLIHDVGIQNLPVTFVLDRAGIVGADGPTHQGQYDISYMRSIPNFTVMA
PKDEAELQRMLVTCLNHDGPTALRIPRGSGVGMPLMEEGWEALPIGRGEL
LREGDDLLIVAYGSMVHPALDTATLLEEAGLSTTVINARFLRPLDQALIH
PLARRIRRVVTMEEGALAGGFGAAVLESLSDQDISIPLLRIGIPDKMVDH
ATPQQSKESLEMIPVQMAERIRRRFDLGGRDFAGAASVPAIQS
>SYNW0119 ahcY, sahH, putative adenosylhomocysteinase
MVAAPTTATELKLGVDCVIADINQAAFGRKELDIAETEMPGLMALREKYG
TEKPLKGARIAGSLHMTIQTACLIETLVELGAEVRWASCNIFSTQDHAAA
AIAAQNIPVFAVKGETLEEYWEYTHRILEWGDGGSPNMILDDGGDATGLV
MLGSKAEQDITVLDNPSNEEETFLFASIKKKLAQDPTFYSRTKAEIQGVT
EETTTGVARLYKMQKSGELPFPAINVNDSVTKSKFDNLYGCRESLVDSIK
RATDVMVAGKQALVMGYGDVGKGSAQSLRGLGATVCIAEVDPICALQAAM
EGYRVVRLEDVVEEMDIFVTATGNYQVIRNEHLEKMKDEAIVCNIGHFDN
EIDVASLKGYEWDNIKPQVDHITLPSGNRIILLAEGRLVNLGCATGHPSF
VMSNSFTNQVLAQIELFTKGNEYGKEVYVLPKHLDEMVARLHLDRIGAKL
TELSKDQADYINVPVEGPYKPDHYRY
>SYNW0634 bioF, putative 8-amino-7-oxononanoate synthase
MASQDPARRRTLHTWSSADLPWTLQRAETEQQPLLDLASNDYLGLSRHPA
VIDAATEALHRDGVGAGASRLVTGSRPCHARFEADLADWLGRSCVLLFPS
GFQANLAAVCILADRHTTVLADRLIHHSLLVGVRASGARLQRFQHNDLTD
LERRLQAMAGQPGSLVVLSESLFSMEGTSPDVAALAAVCQRFGADLLMDE
AHALGVLGAEGRGLCFGIEPVRLISGTFGKAFGSGGAFLACDADLGDALL
QTSGAFRYTTALAPPLVAGAQTALDLIRSHPHWSQQLQQRASHWRDALEG
QGWSRPAGVGPVLPLLLGSDTAALAAQAVLEEHGLLSVAIRPPSVPEGTA
RLRLVLRRDLPNETVEQLLKALPSP
>SYNW0748 cbiA,cobB, putative Cobyrinic acid a,c-diamide synthase
MAVVIAAPASGSGKTLLTLSLLAWARSQGHSIQPFKVGPDYLDPQLLNAA
AGHPCRNLDINLCGKAWVERAFHGYGSQRDLALVEGVMGLFDGIGCSEAG
STAAVAKQLKLPVVLVIDAGGQAASLGALVQGFRDHDPDLTLAGVVLNRV
SSQRHRELLQEVLAAVGMPLLGCLPRSDDLALPSRHLGLAPAHELQNPSQ
RLERWARLAEEHLDLSRWLPLMKAPRSGTPPLDEIAPITGPEMPVAVAVD
EAFHFRYAETGELLERMAMPLLPWSPLADAPLPAKARGLILPGGFPEQHA
ERLGQCRTSLSALRGFAQRHPIYAECGGMLLLGQQLNDLNGTSHPMAGVL
PFSARRGALQVGYRQMTPRQDGLLLRHGESMQGHEFHRWTLEHDRPTSAG
SVLWDIEGWKTGRIPEGWGTQRIHASWIHLHWASSSMICSRWRDALAADP
TP
>SYNW0046 cbiD, cobalamin biosynthesis protein D
MPVWVASAARAALRALLGHPFEPNQQVVQPDGGEPLLVPVRSAARLSDDQ
ALAISRCDPGPGLDLTRDLEIWVRVAWTPSADQGLVLMPGEGVGRIGAGG
DACLSTYARQLLECTLLPLLPPGQGLEVEPVLPRGRSLAERTSNAAFGVV
DGLALIGTQAEVQQSAAPEQLEQVLRELRALVADPGFGGSVALVIGENGL
DLARRAGLSPLLKVGNWLGPVLVAAAEAGVKDLLLLGYHGKLIKLAGGIF
HTHHHLADGRLEVLTALGLDVGLSLEELRHLRAAASVEDAFQRLNPETAM
DLGRLLAATVEQRSQAYIARYGDWSLRIAAVLFDRSRTLRWRGPMAEERF
FTLQD
>SYNW2126 cbiG/cobJ fusion, bifunctional cbiH protien and PRECORRIN-3B C17-METHYLTRANSFERASE
MLFVGAVGAVTRLIAPLIQGKERDPAVLVLDPKGRWVIPLLGGHSSGAEQ
RARELAGMLQADAVLTGACATEDRLALDAFGEGWGWRRAGSSTAWRELMQ
QQACSERLTVAQTSGSTDWQHQHPTLESVTSASEAQVSIGADNQAPCRWH
PASLWLGVGCERNTSLALVQRVIREVLAQAGLAEAAVAGLASIDRKADEP
ALMELGEQRQWPFRTYDATALASVEVPTPSDVVLAEMGTASVAEAAALLA
AGEGAVLRQSKVIRHAATGEQGAVTVAVAEARRPFAPSRGELHLIGSGPG
DLSLLSGDARQTLARCTAWVGYGLYLDLLEPLRQVHQVRLDGQLTREWDR
CAQALSLAQQGARVALISSGDSGIYGMAGLALELWLQQPEQDRPSFQVHP
GISALQLAAARAGAPLMHDFCTVSLSDRLTPWPVIEQRLRAAAAGDFVVA
LYNPRSKGRDWQLAKARELLLEHRRGETPVLLARQLGRSDETHQLTDLSG
LEPEQVDMLTVVLIGNSSSYARADRMVTPRGYPGATVDQWKTLP
>SYNW0213 chlD, Protoporphyrin IX Magnesium chelatase subunit ChlD
MVASGVAVTDDRATRAFPLAAITGHGTLKLALLLAAVDPGLGGVVIAGGR
GTGKSVLARGLHALLPPIDILDVDNGVGRNLDPQNPEEWDDTTRERISGE
PPSKVIPAPFVQIPLGITEDRLVGALDVAASLASGSAVFQPGLLADAHRG
VLYVDELNLLDDGIVNLMLAAVGSGENRVEREGLSLSHPCRPLLIATYNP
EEGNVRDHLLDRFAIALSANQVVSTEQRVEITGAVLSHGQCSRSFAQKWG
EETDALATQLLLARQWLPDVLISREQIEYLVTEAIRGGVEGHRSELYAVR
VARAHAALSGRDTVEADDLQVAVALVIAPRASQMPPPDQQMEPPPPQDQE
PPPPPQDQGDQQQDNPPPPPEGSDEEDSDPPEDSNDDNDTEDDDGDGEED
QAPPAVPEEFILDPEAIEVDPDLLLFNAAKAKSGNSGSRSVVLSDSRGRY
VKPMLPRGPVRRIAVDATLRAAAPYQKIRREREPGRSVIVEEGDLRAKLL
QRKAGALVVFLVDASGSMALNRMQSAKGAVIRLLTEAYENRDEVALIPFR
GDQAEVLLPPTRSITAARRRLESMPCGGGSPLAHGLTQAARVGANALATG
DLGQVVVVAITDGRGNVPLSTSLGQPELEGEEKPDLKQEVLDVASRYRML
GIKLLVIDTERKFIGSGMGKDLAEAAGGKYVQLPKASDQAIAAVAMNAIN
DI
>SYNW1677 chlG, chlorophyll synthase 33 kD subunit
MAPPTGFSKTKSQLPEDFPVSDARQLLGMKGASGTSNIWKLRLQLMKPVT
WIPLIWGVICGAAASGNYQWKLDHVLAAFACMLMSGPLLAGFTQTINDYY
DRDIDAINEPYRPIPSGAIPLGQVKLQIWLLLIAGLAVSYGLDIWANHST
PVVFLLALGGSFVSYIYSAPPLKLKQNGWLGNYALGASYIALPWWAGQAL
FGQLTWSTALLTLAYSLAGLGIAVVNDFKSVEGDRELGLQSLPVVFGIKT
ASWISAGMIDIFQLAMVAVLIAIGQHFAAVLLVLLIVPQITFQDIWLLRD
PVEFDVKYQASAQPFLVLGMLVTALAVGHSPLTQLM
>SYNW0820 chlH, Protoporphyrin IX Magnesium chelatase subunit chlH
MFTQVRSADRRVAPVEGQSHKSVMKAVYVVLEPQYQNALTQAATALNASG
SELGIELSGYLIEELRDEENYAGFCEDVAQADVFVASLIFIEDLAQKVVD
AVAPHRDRLKAAVVFPSMPEVMRLNKLGSFSMAQLGQSKSAIAGFMKKRK
EAGGAGFQDAMLKLLNTLPTVLKYLPVEKAQDARSFMLSFQYWLGGTPDN
LKNFLLMLADKYVFPPAEGEERPAMEVAEPEVFPDLGIWHPLAPMMFEDL
KEYLNWTASRTDLSEEARKGPVIGLVLQRSHIVTGDDAHYVATIQELEFR
GARVIPIFCGGLDFSKPVNAFFYDPLNPEQPLVDGIVSLTGFALVGGPAR
QDHPKAIESLKKLNRPYMVALPLVFQTTQEWEDSDLGLHPVQVALQIAIP
ELDGAIEPIVLSGRDDATGKAHTLQDRVDAIAERAIRWSSLRIKPRIDKK
LAITVFSFPPDKGNVGTAAYLDVFGSIHRVMEEMKAKGYDVQGLPSTPRA
LLEAVINDADAMQGAPELSIAHRMSVEEYERLTPYSERLEENWGKPPGNL
NSDGQNLLVFGRHFGNVFVGVQPTFGYEGDPMRLLYSRSASPHHGFAAYY
TYLQKIWKADAVLHFGTHGSLEFMPGKQMGMSETCYPDSLIGALPNLYYY
AANNPSEATIAKRRGYASTISYLTPPAENAGLYRGLKELGELVGSYQQLR
EGGRGIQIVNTIIETARQCNLDKDVDLPEDDASTLELDGRDALVGAVYRQ
LMEIESRLLPCGLHTIGKPPTAEEAVATLVNIAALEREEDGLRSLPGLLA
EAMGRSIEDIYKGNDYGVLADVELNRTITETSRAAIGAMVRSLTGLDGRV
SMRNSFGWFYDLLAKFGLKLPSPWLRACCGAGFVQIDATELDKLFAYLRF
CLEQVCADMEMESLLKALDGDYILPGPGGDPIRNPGVLPSGKNIHALDPQ
AIPTRAAVAAAKSVVDKLIERQREEQGTWPETIACVLWGTDNIKTYGESL
AQILWFVGVKPMPDSVGRVNKLELIPLEELGRPRVDVVVNCSGVFRDLFI
NQMALIDQAVKMAAEADEPLELNFVRKHALEQAEKEGTSLRDAACRVFSN
ASGSYSSNVNLAVENSTWEEEGELQEMYLSRKTFAFNADNPGEMNQKREV
FENVMKTADVTFQNLDSAEISLTDVSHYFDSDPTKLIAGLRDDGKAPTSY
IADTTTANAQVRSLSETIRLDSRTKLLNPKWYEGMLDSGYEGVREVAKRL
NFTLGWSATSGAVDNFVYEEANDTFINDPEMRKRLLELNPNSFRQIVGTL
LEVHGRGYWETSDENIEQLQELYQEVEDRIEGVVTD
>SYNW0716 chlI, Protoporphyrin IX Magnesium-chelatase subunit ChlI
MTAPRKRRVFPFTAVIGQEEMKLALLLNVIDPRIGGVMIMGDRGTGKSTT
IRALADLLPDIEVVAGDPYNSSSTDPDLQSSEVRERMERGDSISTEPRQV
PMVDLPLGATEDRLCGTIDIEKALSEGVRAFEPGLLAKANRGLLYVDEVN
LLDDHLVDVLLDSAASGWNTVEREGVSVRHPARFVLIGSGNPEEGELRPQ
LLDRFGMSVEVSTVRDPELRVQVVDQRTAFDSDPDGFSTAVEANQDALQQ
RVVEAQQRLGQVSIDDDLRLRISAVCGELDVDGLRGDIVTNRAARALAAF
EGRTEVSEEDVARVASCCLRHRLRKDPLEQVDSGDRVVKVFCKVFERSES
SDRADFELALVA
>SYNW1248 coaD, putative pantetheine-phosphate adenylyltransferase
MRALYPGSFDPLTNGHMDLIERAVALFGQVTVAVLSNPNKKPAFSVDQRI
GQIQCATRHLNGIDVVSFDGLTVHCAVTHQADLILRGLRAMSDFEYELQI
AHTNRSLAEDLETVFLATSTRHSFLSSSVVKEVARFGGPVDHMVPKEVAK
DLNRLFNSTFPPR
>SYNW2354 coaE, putative dephospho-CoA kinase
MQRRIGLTGGIASGKSSVGRLLEARGWPVLDADQYARDALAPNTAASQAV
AHHFGAAVGTAADLDRKALGRIVFSDPDQRRWLEALIHPVVRERFQHELA
ELRDEPVVVLMIPLLFEAGLDVLCSEIWLVDCTPKQQLERMIQRDGLTKN
EAQNRLQAQWPIARKRDRADCVIDNSGGVNDLLAAVSRCGLRADGTTW
>SYNW2475 cobA, putative uroporphyrin-III c-methyltransferase
MTNAEQTGTVYLVGAGPGDPELLTLKAHRLLSQCDALVYDSLVPREVLDL
VPASCERRFVGKRRGHHSVPQPSTNAVLVEMAQKHSTVVRLKGGDPFLFG
RGGEEAAYLAERNIPVQVVPGVTAGIAAPAYAGIPVTHRRAGSSVTFVTG
HEEIDKRRPSVDWRALATASDGLVIYMGLHNLPRIAEELMAGGLAATTPV
AVIQQGTVAGQRCLKATLVDVADQCRAEAFKSPSIVVVGEVIDQQVEACR
PSPAAVTMPILF
>SYNW1704 cobB, Cobyric acid synthase CobB
MNRKRPLMVLGTSSGAGKSLMTAALCRVLHRRGEQPLPFKGQNMSNNAWV
DADGGEMAYSQAMQAWAAGLEPCCAMNPVLLKPRGDSTSEVIHGGTSVGL
ARAEHYYRDWFRPGWQAIREGLQTMQQRWPNGRLVLEGAGSPVEVNLQRR
DLTNLRLAQYLRANCLLVADIERGGVFAQIVGTLALLRPVERPLIKGILI
NRFRGRRELFDEGRSWLEQHTGVPVLGVMPWLNDLFPPEDSLDLLERKPN
RGPTDLEIAVLKLPSISNFSDLDPLEAEPSLRLRWVHPGDSLGSPDAVLL
PGSKQTLRDLETLRSSGLDRQLTAYATNGGSLLAICGGMQLLGQELHDPE
QLEGGDGAGPWPGLGLLPLTTEFGGTKALRQREVQALWPGTTPISGFELH
HGSTWASDDLQPICNEPGLGWWCATPAGGCIAGTYLHGLLDNGPWRRRWL
NQLRERKGLAPLITGLPHHGEHRHQLLERLADAFEQHVDLTPLLQP
>SYNW1651 cobD, putative cobalamin biosynthetic protein
MALQPGVLAVAAATGLDWFLGDPRWMLHPVVVMGWWIQALRRGLESWARD
APWRLRISGGLITVVLVVSSGLLGWAIEWVSRMAGVIGWTVLVIALASAL
AGRSLHDSVMEVLQALPEQATDEPTLARQQLSWIVGRDVTQLQRGGILRA
CAETASENAVDGLFAPLFWMAAGCLLWRLNPAAPGPLALALMFKASSTLD
SMLGYRSGRLRWLGTAGARLDDLLTWLPCRLVMVSLPLVSAPWHRWFALV
QAAEQDGAPDPSPNAGRSEAIYAHCAGVRLGGRNRYGATWVEKPLLAADQ
PEPDRQAIDTILNLTIRLELLWIVLLGLTQ
>SYNW0074 cobH, putative Precorrin-8X methylmutase CobH
MAAMAQDHPIFTESIRRIRVALGPTDLELLQQQVLERLVHSSGDLALGAL
LRFSPGACEAGLTALQQGAPILTDTAMAAAAVAPMAKRTLQTTVRTVLEW
APDQAPLGSTRTAAGMEQAWRELSAVGPAPLVLIGSAPTALEVLLEQVAA
GALSPSLVIGMPVGFVGVAESKRHLAESGLAQIRLEGSRGGAGLVAAAVN
ALLRAAAG
>SYNW0653 cobI/cbiL, PRECORRIN-2 C20-METHYLTRANSFERASE
MPAGLTLVGVGPGDPELLTLAAVRAIEQADVVATPVAREGSASMAATIAS
HCISTKQRLLPLLFPMVSAARPRREAWHLAADALAAEVKAGQAVVLLCEG
DASLFATGSYVLLALQQRHPDCPTRVIPGITAISAAAASAGWPLALQQDQ
LLVMPCPETPDALTGLLETAAQHPRVLALMKLGHRWAWVRPLLERQNMLS
GALFAERVGWPDQIVRSAGDIEASERPYFSLLLVRQGWPDVLP
>SYNW1596 cobL, putative precorrin-6y methylase
MIDVIGTDAGAPASLPAAQQALIRAAEQIAAPRRLQPALETWLESPVPLI
DSDDPRHLVEVLSALSAQTNAVVLASGDPLWFGIGRILAERLGPERLRFH
PAPTSLQLAFARIGRPWQDARWVSLHGRDPEPLARELQTRPRALAVLTDP
GRGGADAVRRCLRSSGLEASYQLWLGENLGHADERMRLIPADAPLPEPLQ
PLLVALLIAEEPSIPNSRALPLFGLEDGLYLQHPDHPGLMTKREARIQLL
ADLDLPDQGVLWDLGAGTGSIGLEALRLRPQLRLLAVERRAGGAALIQAN
AKRLEVMPSAVVETDALSLLSADLPDGLDQPDRVLLGGGGPHREALLKAV
LQRLRPSGIVVIPLATLEAVATLRPLMEQSGLTVQLNQLQAWRGQPLSDG
TRLAPMNPILSLKGT
>SYNW1844 cobM, PUTATIVE PRECORRIN-4 C11-METHYLTRANSFERASE
MTHPVCFVGGGPGAADLLTLRAAERIRQADVLIWTDSLVCPQITALAPDH
CERIRTSTLTLEEVIPLLIDRQRQGAKVVRLHDGDTAFYSAINEQICALN
DADIPVEVVPGVSAYQAAAAGLSSELTIPGVVQTIVLGRAGGRTGVPPSE
ELDRLAGLGASLCLYLSARHIDDVQATLQRHYPDDTPVAIAYRVSWPDEW
MSVVPLAQMAAASKERQLIRTTLYIISPALNGGQQRSRLYSPDHDHLFRQ
RH
>SYNW1750 cobO, possible cob(I)alamin adenosyltransferase
MSSSDLDQSAAELGMGGKLAPEADDAGYRKRMERRQQVQKQRVEERNKEK
GLVLVFTGQGKGKTTAGLGLVLRSLGHGERVAIVQFIKGGWEPGEARALK
AFGDQVSWHALGEGFTWETQDRERDQQLVEEAWQTALGYLRDGAVKLVLL
DELNVALKLGYIDAETVIAGLNDRPELTHVAVTGRGAPAALVERADLVTE
MTLVHHPFREQGVKAQAGIEY
>SYNW1216 cobU/cobP, putative cobinamide kinase
MAADQNTSNLILVSGPSRGGKSRWAEHLLSGSADVTYVATAPDRPNDQDW
QTRLDLHRRRRPSHWRLLESDADLTTALRTIPQQSSVLIDALGGFVACHL
DASDQAWNACCEELVEQLAGMGQTCVVVIEETGWGVVPPTLIGGRFRDRL
GSLAQSLDRQAHSAWLVLQGRAVDLHALSQRVP
>SYNW0742 crtE, geranylgeranyl pyrophosphate synthase
MTVAATSPDNTSGLADIFDFKAYLAKAKATVEQALDQSLVPERPESLREA
MRYSLLAGGKRLRPILCLAACELAGGDAAQAMPTAVALEMIHTMSLIHDD
LPAMDDDDLRRGRPTNHKVYGEAVAILAGDALLTRAFEMVALRSPGVPPE
RLLKVVGELSLVAGAPGLVGGQVVDLESEGKEVDLETLEYIHLHKTGALL
SACVITGAMIGGADDELIAALRVYARGIGLAFQIIDDILDITASSEVLGK
TAGKDLIADKTTYPKLLGLEESRKRAADLVQEAKGVLKPWASKAQPLLAL
ADYITSRDR
>SYNW2164 cysH, Phosphoadenosine phosphosulfate reductase
MDGVRGMTGVLVRDNLDADRGSLEPLSPQDRLAWAHQRFGSGFALTTSFG
IQSAVLLHMLSQLPEGDAVPVIWVDTGYLPEETYRYGAQLTKLLSIRLVV
AQSAMSPARMEALHGRLWDTGQLDDLEKYHQIRKVEPLDRALAQLEVSCW
ASGVRRGQTDHRRAMTVLDPIRERLSLRPLLDWTQKDIYYYMQDNNLPQH
PLFEQGYSTVGDWHSSAPDGAELSGRNTRFGGLKQECGIHVPQEAVEGLM
GDGI
>SYNW0301 dfp (coaBC), putative p-pantothenate cysteine ligase and p-pantothenenoylcysteine decarboxylase
MRTEVSTPLKGRRLLVAVSGSIAAVKTPLLVSALVKAGAEVRCLVTPSAA
KLVSPLALATLSRHRCYTENVEWDSSCSRPLHIELAEWAELVLLAPLSAT
SLSRWSQGSADGLLASVLLACECPVLPAIAMNTAMWSHPAVQRNWQIVQT
FPGVVPLMPQPGLLACDRLGEGRMADPMLIELAASSLFSRCDAGPVATQD
WSGRRLLVSAGPTVEPIDQARLITNRSSGAMGVLLAQAARLRGAEVVLVH
GPLQVPEPWLESLHCHPVSSAAEMQAVLEQQQPGVDAIAMAAAIADLRRD
ATANGSADGKVSKANLAVQLTDGWELVPDLLQGLAARRPAGQLILGFAAL
TGDDNVLRRIGEEKRLRKGCDLLLVNPIDRPGQGFSMPYNGGWLLGDGWT
KQLPVTGKLQLAHQLLDTLLDVSQQVPSSPVPAGQ
>SYNW1485 folB, possible dihydroneopterin aldolase
MTANDAIHVRGLRLWAHVGVLEQERRDGQWFSLDISLWTDLSSAAAADDL
AGSMDYSLAIRSLQALAREIRCLTIEHFSDRVLDRLEQLYGAVPMRLTLS
KCAAPVPGFDGVVAVERARHGAP
>SYNW1635 folC, putuative bifunctional Dihydrofolate/Folylpolyglutamate synthase
MAEHQLSDLIPRFDLRGMDLQLGRMRLALQALGSPCGDIPAIQVAGTNGK
GSIASFLSAALQQAGLRSGVTTSPHLVSWCERIAIDGIPISEGHLRQLLL
AQQELCAEHQLTPFEQLLTAALAHFHAEAVELLVLEVGLGGRLDATTAHP
NRPVIAMASIGLDHCEHLGATLTAIAEEKAAVITPGSRVISSDQPEPVRL
VLEQTCRANNADLQWVDPLPSDWTLGLAGSWQRRNAAVARGALQALQPLG
WNLDETTMRAGFAKASWSGRLQTVTWRGHPLLLDGAHNPPAAQQLALERQ
RWQGHGQGVVWILGIQAHKQALEMLQLLLQPQDQAWIVPVSNHRSWTRDA
LLQTMPHWKDQLIDAASPEDALKRIEETRDWPQPMPVLAGSLYLIGDLLE
QGLVQAE
>SYNW0740 folD, putuative bifunctional Methylenetetrahydrofolate dehydrogenase Methenyltetrahydrofolate/cyclohydrolase
MALRLDGKALAATVERRLTSVVDAHSKTVGQPPGLAVLRVGDDPASAVYV
ANKEKACARVGIASYGAHLAADTPADQVLSTIQSLNADPRVDGILLQLPL
PKGLDERPLLEAIDPEKDADGLHTLNLGRLLKGEPGPRSCTPAGVMALLR
SNGIDPAGQRAVVIGRSILVGQPMALMLQAANATVTVAHSRTADLAAHTR
EADIVVVAAGRPGMVGAEHVRPGAAVVDVGIHRKPEGGLCGDVVAEEVEP
IAAALSPVPGGVGPMTVTMLLVNTVVAWCRRHGIDHELDDLIG
>SYNW1734 folE, putative GTP cyclohydrolase I
MTTTVPFVTNGASNGISNGNGQPRLSAEVSSRIRERLQAAGVSFLANDNI
AEHIEPGELRALEVEVADKVRDLLRTLVIDIDNDHNTHETAERVARMYLH
EVFKGRYHHQPKVASFPNVKKLDEIYTVGPITVRSACSHHLVPIMGNCWI
GIKPGVRVIGLSKFTRVADWVFSRPHIQEEAVMILADEIEKLCEPQGLGI
IIKAQHYCMKWRGVKEPQTSMVNSVVRGDFRHDPSLKQEFFELVRQQEAL
LST
>SYNW0216 folK, possible2-amino-4-hydroxy-6-hydroxymethyldihydro pteridinepyrophosphokinase
MSVAPTAGNDLGVALGANRSSAVGSPRATLLAVRPLLEEQVQVWSSQALG
FRWSELHDTTPVGGPPDQPCYCNAVLLVEGLKAPPGEAAALQLLDALQGL
EQQFGRDRSLEQRWGPRSLDLDLLFWGEFRLEHPRLLLPHPRLHLRTFVL
APLLEAMQGSASR
>SYNW0822 folP, putative dihydropteroate synthase
MISTASWSVVHRSNPTVSPGLPTTRPFDVSHHWPEGWLQRTAVMGVINIT
PDSFSDGGRFIKVEAAVQEAKRQLQQGADVLDLGAQSTRPGAIEVGAEEE
CRRLLPVLAAVRKQWPEVVISVDTFLAPVATAALEAGASWINDVSGGRRD
PELLRVVADAGCPVVLMHSRGNSQTMDDLTDYSDLIQEVKSGLLERTDSA
VTAGVREDQIIWDPGLGFAKTHEQNLKLLKDLEQLTCGPRPLLIGPSRKR
FIGAVLDEPRPKARLWGTAAVACRCAQAGVALVRVHDVGPIAQTLRMASA
LW
>SYNW2309 gshB, putative glutathione synthetase
MRQLFVLDPLSQIRPEKDSTAALMQAAQRAGDDIWSCTPSDLIARGDEPM
AVALPVTPDPWIAVGAPERQSLAGFDVIWMRKDPPVDEAYLYATHLLEVA
ERAGVRVLNRPSALRAWNEKLGALRFSRWMAPTLVAGRVSELMAFAREQG
DVVLKPLGGRAGLGVIRVQAEAPGLKALLELVTEQERLPVMAQRFLPDVT
EGDKRILLVDGDPLGAVNRRPSEGEFRSNLAVGGQAEATELSEPERQICA
ALAPALRAEGLFFVGIDVIGGMLSEINVTSPTGVREVERLMQEPLADQTI
ERLRSLV
>SYNW1117 hemA, Possible glutamyl-tRNA reductase
MHIAVVGLSHRTAPVEIRERLSIPEQTMETSLQSLRGHEQVLEASILSTC
NRLEIYTLVRHPDLGVSAVSEFLSGHSGLATGELTPHLFNYHHEDAVDHL
MRVAAGLDSLVLGEGQILSQVKKMMRLGQEHKSLGPILNRLLTQAVSTGK
RVRSETNLGTGAVSISSAAVELAQLKLGQSRGLDQLVTLESEQIAVVGAG
RMSRLLLQHLQAKGASGVVLLNRTVQRAELLAADFPDLPVQCRPLTDLDQ
CLSTCSLVFTSTAADDPIIDAARLEPLNRRSKLRLIDIGVPRNIAADAAA
VDGVESHDVDDLQEVVARNQEARQAMAREAEQLLQQEAQQFLEWWDSLEA
VPTINRLRSSMETIRVEELQKALSRMGPDFSARERKVVEALSKGIINKIL
HTPVTSLRAPQGRQERQQALRTVERLFSLGDD
>SYNW1933 hemB, possible delta-aminolevulinic acid dehydratase
MELTYRPRRLRRTPALRAMVREHQLSSADFIYPLFVHEGTDVEPIGAMPG
ASRWSLAALTGEVQRAWNLGVRCIVLFPKVAEGLKTEDGAECFNANGLIP
RAIRQIKQEVPGMAIMTDVALDPYSCDGHDGIVSPAGVVLNDETIELLCK
QAVVQAEAGADLIGPSDMMDGRVGAIREALDDEGFEHVGIISYTAKYSSA
YYGPFREALDSAPRAAGSKPIPTNKDTYQMDPANAREAITEAQLDEQEGA
DIMMVKPGLAYLDIIHRLRNESELPIAAYNVSGEYSMVKAAAERGWIDER
AVVLETLLSFKRAGADLILTYHACDAAEWLRQG
>SYNW1785 hemC, Porphobilinogen deaminase
MALTELRIASRRSQLAMVQTNWVKAELEKAHPGLTITVEAMATQGDKILD
VALAKIGDKGLFTKELEAQMLVGRAEIAVHSLKDLPTNLPEGLMLGCITE
REDPADALVVNAKNANHKLDTLPEGAVVGTSSLRRLAQLRHHYPHLSFKD
VRGNVITRLEKLDSGDYDCLILAAAGLERLGFGNRIHQIIPGDISLHAVG
QGALGIECVEDKPEVLEIIKVLEHTTTSRRCLAERAFLRELEGGCQVPIG
VNSQINNEELTLTGMVASLDGKRLIRDEASGSAADPESIGIELAGKLKHQ
GAGAILKEIFDEVRPEA
>SYNW2210 hemD, putative uroporphyrinogen III synthase
MSQPLQNCTVVVTRAADQLGEARRLLETQGAQVLDLPALVIGPPDDWGPL
DDALSELEDFHWLVVSSANGVQAVEQRLQRLGRSLLRRPANLRIAAVGRK
TARALEDLGATADFVPPSFVADSLIDHFPVSGYGLRMLLPRVQSGGRTVL
AEAFGEAGVRVVEVAAYESRCPDAMPERTAEALEAGTVDAILFSSGKTAA
HTAQLLLQRFGPGWEQRLETLKLVSIGPQTSRSCREWFGRIDAEADPHDL
EGLVSACRSLLR
>SYNW1495 hemE, Uroporphyrinogen decarboxylase (URO-D)
MSDTLPLLLRAARGEAVERPPVWMMRQAGRYMKIYRDLRDKYPSFRERSE
NPDLSYEISMQPFHAFKPDGVILFSDILTPLPGMGIDFDIIESKGPQIGD
PIRSMDQVNALRPLNPSESMPFVGEVLGRLRESVGNEAAVLGFVGAPWTL
AAYVVEGKSSKNYAVIKAMAFREPELLHKLLDHFAESIANYLRFQIDSGA
QVVQMFDSWAGQLSPADYDTFAAPYQKKVVDLVKQTHPDTPFILYISGSA
GVLERMATTGVDIISLDWTVDMGEALARLPEHIGVQGNVDPGLLFGTPDA
IEARIDDCVRKARGRKHILNLGHGILPGTPEENGAAFFRSGKSVIDRIGA
FA
>SYNW2040 hemF, Coproporphyrinogen III oxidase
MTVPDGVLSWAGITCLGSSIEWSAFMVRSLVRRLLGRSQNNGTAAPALEL
PPEDSRARARAMVMGLQDEICAGLESLDGEGTFVEESWERPEGGGGRSRV
MREGLVFEQGGVNFSEVQGQELPPSILKQRPEAKGHPWFATGTSMVLHPH
NPYIPTVHLNYRYFEAGPVWWFGGGADLTPYYPFLEDARHFHRTHQAACD
SVHPDLHKVFKPWCDEYFFLKHRGETRGVGGIFYDYQDSSGVLYKGQDPS
GPAAGVSAQLGARPLGWEQLFALGQANGRAFLPSYAPIVEKRHPMAYGDR
ERQFQLYRRGRYVEFNLVWDRGTIFGLQTNGRTESILMSLPPLVRWEYGY
KAEAGSREALLTELFTKPQDWLGDASLEDRCRPHGAIN
>SYNW1747 hemH, Ferrochelatase
MSRVGVVLLNLGGPERIQDVGPFLYNLFADPEIIRLPSPALQKPLAWLIS
TLRSGKSQEAYRSIGGGSPLRRITEQQARELQSLLRQRGLDATTYVAMRY
WHPFTESAVADMKADGMDEVVVLPLYPHFSISTSGSSFRELQRLRQGDAA
FEQLPIRCIRSWFDHPGYIKAMAELIAEEVRNSDDPEKAHVFFSAHGVPK
SYVEEAGDPYQQQIEACTDLIMKSLAEHMGHSNPHTLAYQSRVGPVEWLK
PYTEEALEQLGEAKTNDLVVVPISFVSEHIETLEEIDIEYRELATEAGVV
NFRRVRALDTYPPFIEGLADLVTTSLEGPEVSLDAAAELPTKVKLYPQEK
WEWGWNNSSEVWNGRLAMLGFSAFLLELISGHGPLHALGLL
>SYNW1809 hemL,gsa, glutamate-1-semialdehyde 2,1-aminomutase
MNTSRSQAIFGAAQGLMPGGVSSPVRAFKSVGGQPIVFDRVKGPYAWDVD
GNKYIDYIGSWGPAICGHAHPEVISALQEAIEKGTSFGAPCALENTLAEM
VIDAVPSVEMVRFVNSGTEACMAVLRLMRAFTGRDKVIKFEGCYHGHADM
FLVKAGSGVATLGLPDSPGVPRSTTANTLTAPYNDLEAVKALFAENPDAI
AGVILEPIVGNAGFIQPEPGFLEGLRELTKEHGALLVFDEVMTGFRISYG
GAQAHFGVTPDLTTMGKVIGGGLPVGAYGGRADIMGMVAPAGPMYQAGTL
SGNPLAMTAGIKTLELLKQPGSYEKLTATTEKLIAGIKEAATAAGLPFTG
GSVSAMFGFFLCEGPVRNFEDAKATDSERFGKLHRAMLERGVYLAPSAFE
AGFTSLAHSEADIEATVNAFRESFAEVA
>SYNW1646 hemN, possible oxygen independent coproporphyrinogen III oxidase
MPYPPPPRSAYLHIPFCHRRCYYCDFAVVPLGDRVDAREGPGSRSIEDYL
RLLHREIASAASGPPLSTVYIGGGTPSLLTADQIAELLAALRRQFGLQPG
AEITLEMDPASFDQAQLVAVLAAGVNRISLGGQSFDDAVLIDLGRRHRRA
DLLEACRWMHAAHQDGDLQSWSLDLIQNLPGQTFEHWDDQLDQAIGSQAP
HLSVYDLSVEPGTVFARRAERAELDLPEEDLAVRLMAHTSARLAAAGLSR
YEISNHARPGHASRHNRVYWSGAGWWGFGMGATSAVRGERLARPRTREAY
RRWLEAPPPLNAGSGMPLDELLLVGLRRREGVVLTGRDGQALEERWRPFL
EQGLLQKCSGRWQLRDPEGMALSNRVLLEVVLWWESVQQSTSAAPPQTAA
ARESGPG
>SYNW1746 ilvB, acetolactate synthase
MTLTSASTVVGGLDANAPQTISGAAALMDALRRHGVDTIFGYPGGAILPI
YDALHIAESEGWVKHILVRHEQAGTHAADAYARATGKVGVCFGTSGPGAT
NLVTGIATAQMDSVPMVVITGQVPRPAIGTDAFQETDIFGITLPIVKHSW
VVRDPADLGSIVAQAFLIAASGRPGPVLIDIPKDVGQEQFNYVPVEPGSV
IPGGFHQPEPPLDAAVAAALDLIEQAQRPLLYVGGGAISACAHDSLRMLA
ERYQLPVTTTLMGKGAFDENDALSVGMLGMHGTAYANFAVTECDLLIAVG
ARFDDRVTGKLDTFAPRARVVHFEIDPAEIGKNRKADVAVLGDLGLSLAR
MVEISLQRTAEPRTAAWLERINTWKDRYPLTIPPAEGAIYPQEVLLAVRD
LAPDAIVTTDVGQHQMWAAQHLRNGPRGWISSAGLGTMGFGMPAAMGAQV
AMPDRQVVCIAGDASILMNIQELGTLAAYGLPVKVVIVNNHWQGMVRQWQ
ESFYDERYSASDMLNGMPDFIALARSFGVDGVKITDRELLHRDLAAALQS
PTPTMIDVHVRRGENCYPMVPPGKSNAQMVGLPSHPELAMGTTRTCSSCG
AITAHEHRFCPQCGASL
>SYNW1650 ilvC, ketol-acid reductoisomerase
MAQLFYDSDADLGLLNSKTVAIIGYGSQGHAHALNLKDSGVNVVVGLYDG
SRSADKAKADGLEVLSVADASAKADWVMVLLPDEFQKDVYEKEIAPHLTS
GKVLSFAHGFNIRFELIKPPTDVDVVMIAPKGPGHTVRWEYQNGQGVPAL
FAIEQDASGQARGLAMAYAKGIGGTRAGILETNFKEETETDLFGEQAVLC
GGLSELVKAGFETLVEAGYQPELAYFECLHEVKLIVDLMVKGGLTSMRDS
ISNTAEYGDYVSGPRLITADTKAEMKRVLADIQDGTFAKNFVAECEAGKP
EMKKVRDRDSQHPIEKVGKGLRSMFSWLKDA
>SYNW1239 ilvE, putative branched-chain amino acid aminotransferase
MHQFLPYAWFQGQCVPFEEARISIATHALHYGTGAFGGMRAIPDPQSSGS
MLLFRADRHARRLSRSARLLLTDLSEATILEALTAMLQANKPQQPIYLRP
FVYTSDLGIAPRLHDIETDFLIYGLPLGDYLSPDGVSCRISSWTRQEDRS
LPLRGKISGAYITSSLAKTEAVQSGFDEALLLNSRGKISEASGMNLFLVR
DGQLITPGVDQDILEGITRASVIELAKAMQIPVVERPVDKTELFIADEVF
LTGTAAKITPIRQIESTQMNTDRPVMTALKTRLVSITEGRDTAYEHWVTR
IPIA
>SYNW2130 lipA, lipoic acid synthetase
MLKPEWLRVKAPQRERIGAVADLLLDLNLNTVCQEASCPNIGECFAGGTA
TFLIMGPGCTRACPYCDIDFDKSVRELDPTEPERLGEAVARLGLKHVVIT
SVNRDDLPDGGATQFVACIEQVKQRSPLTTIELLIPDFCGNWDALATVMA
AAPHVLNHNIETVPRMYRLARPQGIYERSLELLQRVRDDWPRAYSKSGLM
VGLGETDDEVIDVLRDLRTHRVDIVTIGQYLSPGPKHLAVDRFVTPEQFD
TYRRIGEEELGFLQVVSTPLTRSSYHAGEVQRLMASHPR
>SYNW0929 lipA, Lipoic acid synthetase
MSKYSTIAPTERLPEWLRRPIGDASALERVQGLVKQNRLHTICEEGRCPN
RGECYAAGTATFLLGGSICTRSCAFCQVEKGQAPMAVDPAEAQRVADAVE
AMQLRYVVLTAVARDDLADHGAALFTTTMEAIRARNPLIAIEVLTPDFWG
GCPDPQQAVAAQRERLSTVLAADPVCFNHNLETVQRLQGEVRRGATYERS
LGLLAACRELAPTIPTKSGLMLGLGESRDEVIAAMRDLRAVDCQRLTLGQ
YLRPSLAHIPVDRYWTPEEFDELGAVARDLGFAQVRSGPLVRSSYHAAD
>SYNW0668 lipB, putative lipoate-protein ligase B
MPVDIGKLVTPVDSAHPGSAILVEPADAVPFERSWADQRHWQQRLLEQPH
LPEAVWLLQHKACYTLGRGASSEHLHFPLDQPPAPVHRIDRGGEVTHHLP
GQLVAYPVLDLRRRQPDLHWYLRELEQVLIDVLAQLDLRGERLPGLTGLW
LDNRKVAAIGVGCRRWITQHGLALNIDCELAGFDQVTPCGLSGRAVGRLV
DWIPGLRLAEVQPLLRDALAARFHLAWCDEA
>SYNW2307 menA, 1,4-dihydroxy-2-naphthoate (DHNA) octaprenyltransferase; UbiA prenyltranferase family
MVEPQAVASRYADRRLLWKAAIKWPMYSVAVMPVLLAAGWRIGAVGSLRW
TQLFGFLLAAILLLLWENLSNDLFDADTGVDTTGKPHSVVNLTGRRDRVA
LASLASLGSGLALMAWLAWCSSVLVLALVLLCCGLGYIYQGPPFRLGYRG
LGEPLCWLAFGPCATAAALMVLEPQGANVIPWATAWMLGAGPAVATSLVL
FCSHFHQVSEDSAHGKRSPVVRLGTARAAALIPWLVALTLALEWLPMCRG
DWPLTVLLSGLGLPAGLALIRLMQRCHDQPDRISGSKFLALRFQAWNGLG
LALGLALGRL
>SYNW0998 menB, Naphthoate synthase
MAELRQVLPGDPAAAWTAWGTYTDILVDRCSEGIARVAINRPAKRNAFRP
QTVVELCDAFSRIRDDRSIGVVLFTGVGPAADGGFAFCSGGDQSVRGDGG
YVGDDGLPRLNVLDLQRIIRSLPKVVIALVAGYAMGGGQVLHLLCDLSLA
ADNAVFGQTGPKVGSFDGGFGAGYLARVVGQRKAREIWFLCRRYGADEAL
RMGLVNAVVPLDQLEAEGVRWAREVLQHSPTAIRCLKAAFNAETDGLAGI
QELAGNATHLFYRTDEALEGRNAFLEKRPPDFSETGWLP
>SYNW0997 menD, Menaquinone biosynthesis protein; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
MTRLVLCPGSRSGPLAAAAGLLAARGDLALTTAIDERSAAFLALGMATAG
GRAVAVVTTSGTAVANLLPAAVEADRSTQPLLLLTADRPARLKNCGANQT
VNQEQFLQPVCRWLGHGAPEGLASQPPQALFDLAHEAWRHCHGRPPGPVQ
LNLPFEEPLHGAPEDQLSLQVSGLQRSAPAPSSDSPLGAAPQLDPNQAGV
VVAGPWRGLAPALPAYQQALLQWLARSGWPLLADPLAAIPADCPGQLDGW
ELQLDRLQLAPGSPVLRLGPLPASRRLEAWLQRQTGPQLLISEGEPRGLD
PLGLADQWSGGLAAWWAEQNQDFPGASTPEQLMPQSGIASLLRQRLPLQG
AVNEPALAHWLPLLLPPQLPVMLAASSPVRDWLIWGGLQAQNRRCFSFRG
ASGIDGTLSLAMGLAMEQGPMVLVTGDLALLHDSNGWLHGAQGNPPLLVL
LIDNQGGGIFQQLPIQSKQFDRLFAMPQRVNPLALAAAHGIDGRQVACLE
DLPEALEWGLAQGRPALLRLATDREADARLRTQLRSAAQNAEPLL
>SYNW2308 menF, Isochorismate synthase
MSADCSFSSVLEASQQGWMSSGGEDTLLSLALPLDGIDPLHALPVLADQA
SFQMLMDGAPGLCLAAAGSCQQLELAGARRFELAQRFTDLSLNRLVDTRA
ISPAQARPRVLLRFRFFEQVGEHHHGAMHPPAVEAVLPRWQLTRQGRRGW
LRLNGVVNSAAEARELAEQLWLKCEQLQADLPFITSSRSPTQLANGNPDL
WKQRYSRAVERGIELVNGGELHKLVLAVRHTIDLDNRFNPLPLLQRLRRQ
QAGSCRFQWQREADDVFFGASPERLLSLRGGWLRSDALAGTAGEGDDGMQ
LLRSDKDRREHELVVDTLTNQLRQMGLTPCRRRQPQLARHGQLTHLHTPI
TAEVQGRSALSLAEQLHPTPAVAGLPRREAMAWLRTLEPFERGCYAAPIG
WIDSAGDAELRVAIRCGHARGRHLDLTAGAGLVRGSIAERERQEVELKLA
VLADQLKLQTSERNRSIV
>SYNW1987 metK, S-adenosylmethionine synthetase
MSRYVFTSESVTEGHPDKICDQVSDAVLDALLAQDPSSRVACETVVNTGL
CMITGEVTSKAQVDFIHLVRNVIKEIGYSGARAGGFDANSCAVLVALDQQ
SPDIAQGVDEADDHEGDPLDRVGAGDQGIMFGYACNETPELMPLPISLAH
RLAKRLAEVRHNGSLEYLLPDGKTQVSVVYENDKPVAIDTILISTQHTAE
VAGISDEQGIRERITEDLWTHVVEPATADLALKPSREATKYLVNPTGKFV
VGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSAAYAARYV
AKCLVASGLAERAEVQLSYAIGVAKPVSILVESFGTGKVSNAELTELVQE
HFDLRPGAIIETFGLRNLPQQRGGRFYQDTAAYGHFGRNDLKAPWEDVAA
KSEELVKAEAKRIKQGATV
>SYNW2460 moaA,narA,narAB, molybdenum cofactor biosynthesis protein A
MTPASALVDQRSRPLRVLRLSLTARCNLACPYCCPDLEDPPDLLSLEQQL
RLIRVACRLGIHSLRLTGGEPLLSARLLPLLQAIAAARATPGDPLQGLQQ
VALTTNGTLLSDQRACDLRQAGLDRITVSLDGVDGAVVARMAGRPTATAG
DSLARKVLGGLASARSAGFDPLAGELKLNAVIQRGVNEDQLLPLADLARD
QGVELRLIEYMDVGNRNQWRLDQVLSAAEMVTRIRARWPLQAVGRPTGGT
AQRWRYVDGGGHLGVIASISEPFCGDCNRLRVTADGQAFRCLFASVGTDL
KPALHCEAELLRLVADLWRRRDDRYSDERQQTTGSMPHAEMAYLGG
>SYNW2474 moaB1, molybdenum cofactor biosynthesis protein B1
MALSIALLTISDTRSLADDSSGDQLQRSLEAAGHRLHERQLCLDDCYQIR
RELSRWIADPAVDVMITSGGTGLTGRDGTPEAVVPLLDKTIEGFGELFRV
LSFESIGTSTLQSRCLAGVANGTFVFVLPGSLDAVTTAWDKLIRAQLDEQ
TRPCNLAQLRARLKE
>SYNW2468 moaC, molybdenum cofactor biosynthesis protein C
MTQNLSHLNQQGEVHMVDVGDRPATQREAHARGAIRMDASTLSLIQRGET
PKGDLLAVARVAAIQAAKRTWELIPLCHPLPLSGMDVTIDADASLPGLVV
HCRCRTTGQTGVEMEAMTAVSVGLLTLYDMLKAVDPAMTIEAIQLEFKEG
GRNGVWER
>SYNW2473 moaD, molydbenum cofactor biosynthesis protein D (molybdopterin converting factor small subunit)
MVLRVLLFASLRERAGWGERSLPFTSGVSTAREVWDQLDLGPLEGISIAV
NQELVGANQPLQAGDELAFLPPFTGG
>SYNW2472 moaE, molybdenum cofactor biosynthesis protein E (molydbopterin converting factor large subunit)
MTGCRVEVCPDPFDPWQQLALWCGDAAAAAIFIGRVRPTTMDGRPLEALE
LEHFPGLCERQITAMAQRLQQEHQAGPILVLHRVGKLAPGEPIVLVAVQA
DRRGAAQRCSAALLEHLKHQAPFWKREWCAGQGTWLVANTPL
>SYNW2461 mobA, molybdopterin-guanine dinucleotide biosynthesis protein A
MLCACLFSGGESRRMGQDKALLPHPSGGLWLTALVDQVRLLGLPLQVVSR
HPTHGDQLADRRGVTVVQEPPPWQGPLQALGRVLPGTPAEALLVLPVDMP
RLSAAVLQQLINSWYEKPDQIAVAQDGQRLQPLLAVIPTGEPFQTRLAEQ
LARGERRWMAWLASVPHRPVVLPSQALLNANRPEDLAALMA
>SYNW2469 moeA, molybdenum cofactor biosynthesis protein MoeA
MSGSAEPYGREGLPLEEARRRVLAAIQPITASNTVPLQQALGRVSAAAVL
ASEAVPGFRASIMDGYALGQSHQPKPGETWLLKGRSAAGQPFNGTLANGD
AIRILTGAPLPDGAGWVLPQELISIDGSSLQLAKKASDRPWIRPEDEECR
PGDLLLSAGQRLGAADLARLAGCGIADLTVAQQPRIGLLISGDELVPPGT
ARQPGAIWESNGTLLETMLRALRQSVTERRVVADQPDALRQALLDLAHDC
DVVVSTGGVSAGDTDWIRPLVAELGAVDFWKLFLRPGRPFAFGSIGEGVP
FFGLPGNPVAAAVTALQLLWPALQVLEGQSEPELFPRVMVELADPLSRRP
GRPELARARLDTNAAGKLLARVDGSQASSRIGSLQQADLLLELPAEAGPL
ERGTRLWAQVIRQRIF
>SYNW1316 nadA, Quinolinate synthetase A protein
MSADTALVAAINRLRQERNAVILAHYYQEPEIQDIADFIGDSLELSRKAA
STDADVIAFCGVHFMAETAKILSPQKTVVLPDLDAGCSLADDCPAEDFAA
FRQKHPDHLVVSYINCTAAVKAQSDLICTSSNAVDLVRQLPADRPVLFAP
DQNLGRWVQQQSGRELTLWPGRCIVHETFSEEAVLQLKLEHPDAEVIAHP
ECQENLLDLADFIGSTSKLLNHTQSSAADTFIVLTEPGILHQMKQRVPTK
TLIDVPGLDGCSCNACPYMRLNTLQKLHDCLETLEPAVELNEELRQQALR
PIERMLELSR
>SYNW2192 nadB, putative L-aspartate oxidase
MDPSRPLDAIDPGPWDVVVVGAGAAGLMTCLELPEGLSVLLLNRNTGRRS
SSRWAQGGIAAVTRPEDSAGSHADDTLNAGAGLCDGDAVRFLVDAAPRCV
DRLQQLGMAFDRDGHGLATTLEAAHSHRRVLHVQDRTGRALVDVLRERVE
RRPGLLHRRGVRVTRLDVQNGRCCGVQVLDGRHLQHIQARAVVLASGGGG
HLFANTTNPAQACGEGIALAWQAGAAVEDLEFVQFHPTALRLDDAPCFLI
SEAVRGEGGVLVDAQGGSPVDHLLQRDLAPRDQVSRALVQRMWEQGVAQM
WLDFSAIPRAQAEARFPTILDRCSEFGLNPLERPIPVAPAAHYWMGGVAT
DLQAATDLPGLYAVGEVACTGVHGANRLASNSLMECLVFAHRLAEIDLGP
AIKPSNPAPPQAYGQALEGAITSAGLMEQIEQLRLFCWQRAGVDRSGRRL
NAGLDHLRCELERLDQQPLLNCLQRDALLLDDSSRRDLNLLLDLRHRLVT
SKLMLEACLFRQESRGGHFRTDAPSSQPQWQCHSRQSRARGLHTRAVRP
>SYNW2320 nadC, Nicotinate-nucleotide pyrophosphorylase:Quinolinate phosphoriobsyl transferase
MSGMDWQSSALTRALDRWLEEDIGRGDLTASALQRKHGYAHWIAKQPGCF
CGGPLVQQLFQRLDPEVSVHLLRDDGAAVEVGDRLLDLEGPATALVAGER
TALNLAMRLSGIATATAELVAQLQGTGVRLADTRKTTPGLRLLEKYAVRC
GGGINHRMGLDDAAMLKENHIAWAGGITMAIAAVREQAPWPTAVIVEAET
EAQALEAVRAGANGVLLDEFSPKQLTQLVPRLRASSTGVVVLEASGIQPE
QLQAYAATGIDLISTSAPVTRSRWLDLSMRFT
>SYNW2315 pabA, para-aminobenzoate synthase component II
MLLVIDNYDSFTFNLVQYLGELAPHYPIAADLQVHRNDALTLAQIRELKP
DAILLSPGPGDPDQSGVCLEVLQDLSPTTPTLGVCLGHQAIAQVHGGRVV
RASQQMHGKTSPVLHNGEGVFAGLPQPLTATRYHSLIAERSSLPDCLEVT
AWLEDGTIMGLRHREHRHLQGVQFHPESVLTDAGHQLLANFLKEANGERC
>SYNW1645 panB, putative Ketopantoate hydroxymethyltransferase
MRPADLIRQKQNGRTITILTAWDSLSAALVEAAGADAVLVGDSLAMVALG
HATTLPVTLDQMRHHTLAVSRGFAAAPSKQPLLICDLPFLSYQCGADLAV
QAAGTLLKETPAAAVKLEGAEAEVLAVIDRLVRMGIPVMGHLGLTPQAVH
RLGYRRQAEDPVSQERLLTQAIALEQAGCFALVLEHVPSALAREVRRRLL
IPVIGIGAGDDCDGQIRVTADLLGLTEQQPPFSPALIPGQQLFVEALRTW
IAAQTPTTTPPPATPDY
>SYNW2027 panC, cmk, putative bifunctional enzyme; pantothenate synthetase/cytidylate kinase
MLSTQAELAAFHSGLGQPLQFVPTMGGLHQGHGELIRRAAEQGPVLVSVF
VNPLQFAPGEDFERYPRSLEADLALADRYGAAALWTPTVQTIYPDGATAD
SARQAPAALQQHLCGADRPGHFDGVVTVVARLLELTRPAGLWLGEKDWQQ
LVILRQLVADLVLPVKIHGVATVREADGLALSSRNQYLSAAQRLQAAALP
AALRAADGTTPLDVTRSRLSAAGLEVEYVERVDPQSLQPCGSETALSLLA
AAVRCGTTRLIDHSFLMTRQPLVAIDGPAGAGKSTVTRAFAERLGLIYLD
TGAMYRAVTWLVQQQGVEPGDAAAVDALLRALDLQLQSLPGGGQQVMVNG
EDVSQAIRSPEVTGSVSVVAAHRCVRQALTTQQKAMGAKGGLVAEGRDIG
SAVFPDADLKVFLTATVAERARRRALDLEQRGFPVQERSELEAQIAERDH
LDSTREEAPLVQAIDAVELVTDGMSIDAVIDALVEQFRARVPEEAWPTPA
G
>SYNW0035 pdxA, putative pyridoxal phosphate biosynthetic protein PdxA
MPSPLDHNASQQLLIALGDPAGIGMEVTLKALASSRLPASLQPVLVGCRR
SLMATHARLLQQGITAVADPDQLIIDDQPLEVSVQPGQPTTAGAAACFRW
LTHSVACVQHGHGRALVTAPIAKHLWHAAGHHYPGQTERLAELAGSQQSS
MLFTAVAPHGTWRLNTLLTTTHLPFSQITAALTPELVEHKLNVLLNFCQR
FRPDPHLVVAGLNPHAGEAGRLGQEEDTWLSPLLKRWRQEHPSVRLDGPI
PPDTCWLSAAQAWNQPDGSGPDGYLALYHDQGLIPVKLLAFDAAVNTTLE
LPFLRTSPDHGTGFDIAGQGLARPDSMIAALQAAWDLTAA
>SYNW0910 pdxJ, Pyridoxal phosphate biosynthetic protein PdxJ
MASLGVNIDHIANIRQARRTVEPDPVPFAMLAELGGADGITVHLREDRRH
IQDRDVQLLRQTVRSRLNLEMAATQEMVEIALAVEPDMVTLVPEKREEVT
TEGGLDVAAQLSGLTPMVERLQQRGIPVSLFVDAETTQLEACRNSGAHWV
ELHTGTYADASWADQPGQLARITEGAATARHLGLRVNAGHGLTYQNVEPI
AAIPGMEELNIGHTIVARAVAVGLQQAVREMKALIQNPRLDPLFGHALG
>SYNW1263 ribA/ribB, possible GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase
MATSNQQLIVQRLIMMELQYGRLLNSSSQHQQDDPIRFDDIAEALAAIRN
GACVVVVDDEQRENEGDLICAAQFATPEAINFMATEARGLICLAMEGKRL
DELDLPLMVDRNTDANETAFTVSIDAGAEHGVSTGISAEDRARTIQVALN
PKTRPAELRRPGHIFPLRAKPGGVLKRAGHTEAAVDLAQLAGLTPSGVIC
EIQNSDGSMARLPELRAYADTWGLKLISIAELIRYRLDNERFVRRQAHAE
LPSQFGSFQAIGYCNELDGSEHVALVKGDPASLREPVLVRMHSECLTGDA
FGSLRCDCRPQLEAALRQIEREGEGVVVYLRQEGRGIGLINKLRAYSLQD
GGLDTVEANERLGFPADLRNYGVGAQILSDLGIHRLRLLTNNPRKIAGLG
GYGLQVEERVPLVMDAGDHNADYLAAKRDKLGHLMDSDGPCTVLAVAVND
RTESLPSIRSRVEDLAETHGQTLEALHEPRLLALWDRPQFVWKLTPEVDA
PLALLQSIAQLESTQRIGLLRVSTERSALHPSQTLEREERSLVELIQTNG
DERLTQRPSLLHWSARD
>SYNW1590 ribD, putative Diaminohydroxyphosphoribosylaminopyrimidine deaminase and 5-amino-6-(5-phosphoribosylamino)uracil reductase
MWNLWMRRALALAALAEGRTSPNPLVGAVVLNREGRLVGEGFHARSGEPH
AEVGALAQAGTAAAGGTLIVTLEPCCHHGRTPPCSRAVLQAGVARVVVAL
EDPDPRVAGGGIAQLRKAGVVVITGVLRQEAAEQNRAFLHRVRTGRPWGV
LKWAMGLDGRTALPNGTSQWISGADSRRWVHQLRAGCDAVIVGGGTVRAD
DPLLTSRGRRDPEPLRVVLSRGLDLPAEAQLWDTASAATLVAHGPEAAGK
QAPNGPERLELEQCEPLPLMQHLAARGCNQVLWECGSELAAAAIRQGCVQ
EVAAVLAPKLMGGVAARTPLGELGFTAMDQVLCGQLLPPRPIGDDWLLSL
RLGG
>SYNW1865 ribE, Putative Riboflavin synthase alpha chain
MGRIQRRGNGLLVEGAGPFGPLSLGDSVAVDGVCLTVAECVGEGFRADVS
EETLERTTLGRKAERGGAVNLEPALRLSDRLGGHLVSGHIDAVGEVMDVV
ELPQSWRLGLRWSEPRFGRYVCEKASIAVDGISLTVASCSDDGVTFELAV
IPHTWSVTTLSRLAVGDQVNLEADQLARYAERLLVADGQDNHHSTPAMSE
AWLSENGWT
>SYNW1603 ribF, putative riboflavin kinase/FAD synthase
MIPLCSPQDARRPTALALGSFDGLHAGHRRVIGQAIAGSTAVPTVVSFWP
HPREVLFGEARLRLDLPSEKLELLQPLGIEQLVLVPFTPELAQLSAEAFV
NTVLLDTLQAQRIVVGANFRFGNKRSGDADLLRQVAAARGVEVLVTEIVE
DGNGRMSSSRIRAALDIGDLDTAKSLLGRPYRFRGRVVRGRGLGRELGWP
TANLQVDGRKFLPALGVYAAWAWVDGGDQPLAAVMNMGPQPTVDPTSPSA
VEVHLLDRTIELEGRQLTVEPVQRLRGQQRFSGLEELSAQIGRDADQARS
LLSVQTGVG
>SYNW0082 ribH, Putative 6,7-dimethyl-8-ribityllumazine synthase or riboflavin synthase beta chain
MTTFEGRFTDTADLRIAVVVARFNDLVTSKLLSGCLDCLSRHGIDTAETS
SQLDVAWVPGSFELPIVAQNLAQSGRYQVVITLGAVIRGDTPHFDVVVAE
ASKGIATVARESGVPVIFGVLTTDTMQQALERAGIKSNLGWSYGLQALEM
GSLMAALAQS
>SYNW1384 rimK, possible ribosomal protein S6 modification protein
MTRKIIVGSEEWCSLPGLGLPAIKARVDSGAATSSLHAFNIVPFQRDEAR
WISFEVHPLQNDRSVVIRRESPVLEQRGVRNTSGITETRYVIREQLVLGE
ESWPIELTLTNRDAMGYRMLLGREAMVGRVLVDPEGSHQLGDLRQDQLEA
MYAPLRTERNGLRIALLASDPELYSNRRLLEAGEERGHRMEFLNVKQCYM
RLDPQNPEMHYRGGNVLERINAVIPRIRPSVTFYGCAITRQFEAMGISVL
NAAEPIKRSRDKLLASQLFVRHGLNMPVTGFASSPLDTKDLIKMVGGAPL
ILKLLEGAQGRGVVLAETQKAAESVINAMKSLNANLLVQEFIKEAGGKDL
RCFVIGGKVVSAIERTAAVGDFRSNIHQGGSAQAVRIRPEERKLAVSATR
ALGLDVAGVDIIRSERGPLLLEVNSSPGLEGIETATGKDLAGLMIQEIER
KLGWVRTRLSEPQVAC
>SYNW1011 sds, polyprenyl synthetase; solanesyl diphosphate synthase (sds)
MITVTELLQPVETDLETLLGDLRSLIGAGHPILQAAAEHLFSAGGKRLRP
GIVLLLSRALSADGQLTPRHRRLAEITEMIHTASLVHDDVVDEASTRRGV
DTVHSRFDARVAVLAGDFLFAQASWHLANLDDLEVVKLLSRVIMDLADGE
VKQGLFRFDTAQSFETYLEKSYCKTASLIANSARAAGVLSDCSPSELDGL
YRFGRQLGLAFQVVDDILDFTGSDQQLGKPAASDLASGYLTAPTFYAMEE
QPGLQALIAREFAEPGDLDQALEMVRSSRAIPRTRELAETFARESRDAIS
WMSDSPCKRALLELPDFVLSRLY
>SYNW0533 serA, putative D-3-phosphoglycerate dehydrogenase (PGDH)
MSKVLVSDPIDQAGVDILSQVAQVDQRPGLSPEELVSVIGDYDGLMIRSG
TQVTAEVIAAASKLKIIGRAGVGVDNVDVPAATQRGVLVVNSPEGNTIAA
AEHALAMMLSLSRHVPQAHAGMRVGKWDRKKYVGNELYKKTLGVVGLGKI
GSHVARVARAMGMEVIAYDPFIAADRAQQMQVRLTELDELFRTADYVTLH
IPRTKDTENLVNAELLRTMKPTARIVNCARGGVVDEAAIAEAINGGVIAG
AGLDVYASEPLAEDSPLRAVERGLVLTPHLGASTEEAQENVAIDVAEQIR
DVLLGLPARSAVNIPGLSAEIMERLKPHLQLAETVGGLVSQLSGGQVQEL
ELRLQGDFASHPSQPLVIASLKGLLGAVLGDSINFVNASLEAKARGIRVL
EVKDEASRDYAGGSLQLISRGDQGSRSVTGAVFADGELRITSIDEFPVNV
TPSSHMLFTRHRDMPGIIGQLGSMLGEHNVNIAAMQVGRKIVRGDAVMVL
SIDDPIPAALLQTITAIEGIQEAHPVSL
>SYNW0140 thiC, thiamin biosynthesis protein
MIEQAVADLWLPIAVLIMRASWVSPRKGQANVSQMHYARQGVVTEEMAYV
AKRENLPESLVMEEVARGRMIIPANINHTGLEPMAIGIASKCKVNANIGA
SPNASDAAEEVNKLKLAVKYGADTVMDLSTGGVNLDEVRTAIIDASPVPI
GTVPVYQALESVHGSIEKLDEDDFLHIIEKHCQQGVDYQTIHAGLLIEHL
PKVKGRLTGIVSRGGGILAQWMLYHHRQNPLYTRFDDICEIFKRYDCTFS
LGDSLRPGCQHDASDAAQLAELKTLGELTRRAWKHDVQVMVEGPGHVPLD
QIEFNVKKQMEECNEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWHGTA
MLCYVTPKEHLGLPNAEDVREGLIAYKIAAHAADIARHRPGARDRDDELS
RARYNFDWNKQFELSLDPERAKEYHDETLPADIYKQAEFCSMCGPKHCPM
QTKITEEDIEGLEKVLEARGAAELTPVKLDKAD
>SYNW1604 thiE, Thiamine monophosphate synthase (TMP)
MGCESSLDPRVARLIDANLDRAREGLRVVEDWCRFGLERDDLVISLKDWR
QRLGKLHQERYKRARSTVTDPGAGMEHPAQLDRHSPRQVVEANCGRVQEA
LRVLEEYGRNVDAPLSAEAAAIRYGLYDLEVTCLTATSGNNRRNRLQDCQ
LCLITSPCPDLVDRVKTALRSGVAMVQHRCKSGSDLERLAEARTLAALCR
DHGALLIINDRIDLALAVDADGVHLGQDDLPTDVARGLIGPGRLLGRSTH
SLNQVAEAHREDCDYLGLGPVNNTAVKPERPAIGAALVGEALAITHKPVF
AIGGISQANLDALMAVGCRRVAVIGAIMGSDNPEKASQNLLSSLSRPTL
>SYNW0054 thiG, thiamin biosynthesis protein
MVPNPPISLAQGDDLIIGGRRFHSRLFTGTGKYPSMEVMQQSIKRSACEM
VTVAVRRVQAVAAGHAGLMEAIDWTRIWMLPNTAGCTNAEEAVRVARLGR
ELAKLAGQEDNTFVKLEVIPDGRHLLPDPIGTLQAAEQLVNEGFTVLPYI
NADPLLAKHLEDAGCATVMPLGSPIGSGQGLNNAANIALIIENASVPVVV
DAGIGVPSEAAQALEMGADAVLVNSAIALARNPAAMAEAMGQAVIAGRTA
FCAGRLPRREEASASSPTTGLVSS
>SYNW0031 thiL, putative thiamine monophosphate kinase
MTPTLAELGEAELLKRLARFAPPGQLDDDTACLGADPRPLLVNTDVLVDG
IHFSDATTDAHDVGWRAVAANLSDLAASGAVSIDGITVALVAPGTTPWSW
VEGVYNGISAALQQHGGTVLGGDCSSGVSRLLSVTALGRLGPLQLLRSTA
QPGDVLVSSGPHGLSRLGLALLQNDPQLQATCLNASLQSQAISQHQRPRP
RLDALHQLLSCKPAHLPWRAGGTDSSDGLLTAVRGLCSSSGTGARLDRKL
LPKAHGWPDGDPWERWCLAGGEDFELILSLPAAWADALEQALPGCQRFGR
ITNNAGSVIWSDDNSPIMDEGFNHFAQG
>SYNW2045 trpE, Anthranilate synthase component I and chorismate binding enzyme
MLSPDRVAFHEAAANGANLIPLAQSWPADLETPLTAWIKVGADHAPGVLL
ESVEGGETLGRWSVIACDPLWTASARNDCLQRRWRDGREETFRGNPFDSL
RRCLEPYRCISLPGLPPLGQLYGVWGYELIQWIEPSVPVHPRQESDPPDG
IWMLMDSILIFDQVKRQITAVAFADLSQGQSEDAAWDGAMARIAALRRRM
EAPLPLVDPLPWDAQAKQLPDVKSNCSQERFEAAVDTAREHIAAGDVFQL
VISQRLETVVPQQPLELYRSLRMVNPSPYMAFFDFGDWQLIGSSPEVMVQ
ADPAPEGIRASLRPIAGTRPRGTTAHEDRDLELDLLADPKERAEHVMLVD
LGRNDLGRVCQPGSVAVKDLMVIERYSHVMHIVSQVEGRLAPQHDVWDLL
MASFPAGTVSGAPKIRAMQLIHELEPDARGPYSGVYGSVDLAGALNTAIT
IRTMVVQPDPSGGCRVKVQAGAGVVADSKPTAEYQETLNKARGMLTALAC
LNPERP
>SYNW1847 ubiA, probable 4-hydroxybenzoate-octaprenyltransferase
MDSIRERLGPWLELLRWTKPTGRLILLIPAGWSLWLSPSAPPGLDLLLQI
VVGGLAVSGAGCIANDLWDRRFDGRVERTKQRPLARGAIRPTSALVLLIV
LLSLSLAVVLSLDEASRQLCLLLSIGALPAILLYPSAKRWFAYPQAVLAF
CWGFAVLIPWAAAERSLTLQPALIGCWLATLLWTFGFDTVYAMADRRDDA
LIGLNSSALSLGNRAVVTVRACYVLTVVALGVAAASAGVHPLFWIFWLGA
SLLMQISCQSLNHRNATMASFGLHFRRQVQLGSLLLLGLIVSRGLSG
>SYNW0816 ubiH, possible 2-octaprenyl-6-methoxyphenol 4-monoxygenase; UbiH
MATSSTTFHILGAGPTGSLAAIALASTGCSVVLTDPLTRKELLSRSRAYA
ITHSSRRLLTDLNLWTSLQGSLTAFSFLDLRDSACGGRVVFGLDDLPNSN
GRHEAIGWILDHQPLMKLLMDRLHQHHRVELALGCTAPTPGIDDLIVAAD
GPRSTTRSQWDIGCWKFRYRQGCLTSKIALRGVKPGMAYELFRPEGPFAI
LPLGDGIFQVVWSAPWTQCQRRADLPTPEFLDELAAVLPAGIEPDLLLDT
PRAFSQQWSMARRLSRGRGVLLGEAGHRCHPVGGQGLNLCWRDVASLRNL
AEHGGTSQRLARRYGRSRWADLLMVGLATDLLVRLFSNQQPWLLPFRRIG
LKAMARFSWLRRISLLAMTDGPTQLLKPLPD
>SYNW1201 ubiX, putative 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MHPYVLAVTGASAQPLAERTLQLLLQAGRSVHLVLSRGAYAVFQAEQGVQ
VPVNPERQASFWRERLNCSEGELFCHRWNDQSVGIASGSFRTSGMLIVPC
SMGTAGRIQAGVAMDLIERCADVHLKEGRPLLIAPREMPFNLIHLRNLTA
LAEAGARIAAPIPAWYTQPRTLEEMVDFIVIRLLDGFEDDLAPLQRWTGP
IK