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# Streptococcus pyogenes phage 6180.4

>M28_Spy0456 PTS system, beta-glucoside-specific IIABC component
MTYQETAKAILAAVGGKTNIQRVTHCVTRLRLVLKNDEKVKDQQVKAISN
VIGVMRKNGQYQIILGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILER
LIETIAGVITPLIPALLGGGMLKVVGILLPMLGLASADSQTVAFINFFGD
AAYYFMPVMIAYSAAARFKVTPVLAATIAGILLHPAFVAMVAEGKPLTLF
GAPVTPASYGSSVIPILMMVYLMQYIEKWVNRLVPSVMKSFLQPTLIILI
SGFLALVVVGPLGVIIGQGLSNTMLAIYHVAPWLALAILGAIMPLVVMTG
MHWAFAPIFLAASVATPDVLILPAMLASNLAQGAASLAVAFKTKQKQTRQ
VALAAGISALLAGITEPALYGVTLKFKKPLYAAMISGGLVGAFIGFVNIA
SYTFVVPSIIGLPQYINPSGGANFINALIAGAATIVLAFSLTWFMGIDEE
SPKQVSVAADMSQVKSGLSTKQTLYAPMTGEMLFLSEVPDETFSSKLLGE
GFAILPSEGVVYAPFDGEVITFFPTKHAVALKNTRGVEVLIHVGIDTVEL
KGQGFEQLVSVGDVVKRGQALLKMDIDFITSKGYSLISPVVVTNSAEQLE
IIIQDDKKMVTKEDALLVIL
>M28_Spy1649 transaldolase
MMTKKLNVKVFSDGAVLETMLKDLQTGLVTGFTTNPSLMKKAGISSYIGF
AKEVLAKITDYPVSFEVFADDLASMEKEAEKIASLGDNVYVKIPVTTSTG
ESTCPVIQKLSAKGIKLNVTAIFTIEQTQAVVDHLTAGVPAIVSVFAGRI
ADTGVDPMPIMEEALRICRQKEEVELLWASPRETYNIYQADQLGVDIITC
TTDLIAKLPLQGKDLEDYSLETVQMFLKDSTSLGFKILEDDNH
>M28_Spy0505 2-dehydro-3-deoxygluconokinase
MNSNSILTRKGGHMSKLLLVGEPLIRVSPNQFQPLTNACDAQLFFGGSEA
NIARTLGGFGLEARLFTALPDNPVGHAFHQFLKQSGVDMSLTAWQGHRVG
LYYLENGFGCRASQVYYDRCGSSFSALDKDSLDLAAIFEGISHFHFSGIS
LALGKKTQDLIEILAREARKRQVCVSFDLNFRSSMIAVADAKRLFSHFAQ
YADIIFGMEPLLLDSDDFDMFDRNKADTTMIRERLAGLYQRYQLQAIYHT
ERSNDAQGSNRFKAYAYDGQFYESCEVTTPVLQRVGSGDAFVAGLLYQLL
EGNEKQRNLDFAVATASLKCTVAEDQLYHSVQQVEAVLHNQRDVQR
>M28_Spy0476 phosphoglycerate mutase
MKLYFVRHGKTLWNLEGRFQGAGGDSPLLEEAKDEIHLLGKELAKVAFDA
VYTSDLQRAMATAAIILDAFDQQPKLYHTDQLREWRLGKLEGAKIATMAA
IYPQQMLAFRENLAQFKSDQFEAESIYQTTQRVCHLIQSFKDKHYQNVLI
VGHGANLTATIRSLLGFEPALLLAKGGLDNTSLTILETKDYLTYDCLIWN
DKSFLEV
>M28_Spy0757 PTS system, mannose/fructose family IIA component
MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYTSQIDNF
IAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLS
LVFLKPGEALTKDDIVTVINESQVQLVDLVPETNSEDDFFD
>M28_Spy1354 beta-glucosidase
MLAFPKEFWWGGATSGPQSEGRFAKQHRNLFDYWYEEEPDLFYDYVGPDT
ASDAYHQIESDLALLASLGHNSYRTSIQWTRLIDDFEQVTINPDGLAYYN
RVIDACLANGIRPVINLHHFDLPIALYQAYGGWESKHVVDLFVAFSKVCF
EQFGDRVKDWFVHNEPMVVVEGSYLMQFHYPAIVDGKKAVQVAYNLALAT
AKVIQAYRQGPAELSDGRIGTILNLTPAYPASQSEADMAAAHFAELWNND
LFMEAAVHGKFPEELVAVLKKDGVLWQSTPEELALIAENRVDYLGLNFYH
PKRVKAPDVIPVISPSWSPEWYYDAYLMPGRRMNVDKGWEIYPEAVYDIA
IKMRDHYDNIPWFLSENGVGISGEDRYRDETGQIQDDYRIRFLKEHLTYL
HKGIEAGSNCFGYHVWTPIDGWSWLNAYKNRYGLVENNIHTQVRRPKASA
YWFKKVATHNRLISLEVMEEFGGSASHLSD
>M28_Spy1889 glucose uptake protein homolog
MEGIFYALIPMFTWGSIGFVSNKIGGKPSQQTLGMTFGALLFSLAVWLIV
RPEMTLQLWLFGILGGFIWSIGQTGQFHAMQYMGVSVANPLSSGSQLVLG
SLIGVLVFHEWTRPMQFVVGSLALLLLIIGFYFSSKQDDANAQVNHLHNF
SKGFRALTYSTIGYVMYAVLFNNIMKFEVLSVILPMAVGMVLGAITFMSF
KISIDQYVIKNSVVGLLWGIGNIFMLLAASKAGLAIAFSFSQLGAIISIV
GGILFLGETKTKKEMRWVVTGIICFIVGAILLGVVKS
>M28_Spy1499 pyruvate, phosphate dikinase
MKERYFFCDVVGKYLEEYVDRGIFDKEPFQTFDQKGIGRLFSPFG
>M28_Spy1060 PTS system, cellobiose-specific IIC component
MSHFSDKFMEISGKIGSQRHLVAIRDSFISMMPITMAGSVAVLLNVFLRD
IPNNMGWTGFAKAMQPVIDINGYVYFGTIGIMALFFAFAFGYNLAVMHKI
NPLAGGLISFGSFIATLPQTLTISTPLENASANLISNLKEMGLSVVTAGG
ASSIETSQWGAIALKYVGATGLFTALIIGFLSSFVYAALTKRNITITLPD
NVPPAVNKAFAAIIPGTVAIYASAIFAYLIFALTGSSLSDVISTYIQLPL
LGLSQGIGSVILLTFLVQLLWFFGLHGHNVLAPVMDGIYMVALTENTAAY
NTAHSAANLPYLWTRGSFDAYAQMGGSGVTLALIIAIFIFSKREEHKTIA
KLSAPMGIFNINEPITFGMPIVLNPTFVIPWLIVPPICASIAYFATAIGL
IPPVFLSVPWITPVGLYAYLATGGNIMAGLVSLFNLFVAFLIWAPFVILA
NKEKASDLA
>M28_Spy1498 pyruvate, phosphate dikinase
MAVSLARSVKPELKLGICGEHGGDPASIDFYHSQGLTYVSCSPFRVPLTR
LAAAQAAIKASGHSLTQDK
>M28_Spy1732 PTS system, cellobiose-specific IIB component
MTKKEIDMIKIGLFCAAGFSTGMLVNNMKVAAEKKGIDCQIEAYAQGKLA
DYAPLLDVALLGPQVAYTLDKSEAICKDNDIPIAVIPMADYGMLDGNKVL
DLALSLVKE
>M28_Spy1075 transporter, MFS superfamily
MSTLSLDTTNKRALVAAIAASGTDDLNVMFLAFSMSSIMTDLSLSGTQGG
WIATITNLGMLVGGLLFGLLADRHHKFKVFKWTILLFSVATGLIYFTQSL
PYLYLMRFIAGIGVGGEYGVAIAIMAGIVPPEKMGRMSSLNGIAGQLGSI
SSALLAGWLAPSLGWRGLFLFGLLPILLVIWMTLAIDDQKIWDHYGQEEE
ECSQPIKINELFKTKSLTAQTLALMVMTTVQIAGYFGMMNWLPTIIQTSL
NLSVKSSSLWMVATIVGMCLGMLCFGQLLDCFGPRLIYSLFLLASSICVY
LFQFANSMASMVIGGAIVGFFVNGMFAGYGAMITRLYPHHIRSTANNVIL
NVGRALGGFSSVAIGSILDASGISMVMIFLASLYVISFGAMWSIGQLKAE
RYQQLR
>M28_Spy0148 PTS system, 3-keto-L-gulonate specific IIA component
MNLKQAFIDNNSIRLGLSADTWQEAVQLAVQPLIDSKAVTSAYYDAIIAS
TEKYGPYYVLMPGMAMPHAEAGLGVNHNAFALITLTKPVTFSDGKEVSVL
LTLAATDPSIHTTVAIPQIVALFELDNAIERLVACQSPKEVLEMVEESKN
SPYLEGLDLDS
>M28_Spy0502 PTS system, N-acetylgalactosamine-specific IIA component
MIAIIVMGHGHFASGIVSSLELIAGPQEKVTAIDFTTEMTAADVQDQLSR
ALIPEEETLVLCDLLGGTPFKVAATLMESLPNTTCNVLSGLNLAMLIEAS
FARQTAASFDDLVSGLITCSKEGIVDWKTLSQQEDGTTDDELGGI
>M28_Spy1111 peptidoglycan N-acetylglucosamine deacetylase
MKKLNLILVGLLSILILSLAIVFINRWKLNEDSQRIVLAEKKKNTSDLVI
KAVKHIKKDQKDYYYFSPIKQADDFFVDNLPVSLYKKKNSDKELILVKPK
LQSSHLRSVNTLTISKIVYQKKFFHLAKKSEKVISTYHVTDDLKPFQVRD
LVSGHLERIQEEVEKKYPNAGFNSDKYNGLKESNSLLSDGFEVKSGNLIF
DKKLTIPLTTLFDVINPDFLANSDRAAYDNYRTYKEQHPKKLVALTFDDG
PDPTTTPQVLDILAKYQAKGTFFMIGSKVVNNENLTKRVSDAGHEIANHT
WDHPNLTNLSVSEIQHQVNMTNQAIEKACGKKPRYLRPPYGATNATVQQS
SGLTQMLWTVDTRDWENHSTDGIMTNVKNQLQPGGVVLMHDIHQTTINAL
PAVMEYLKAEGYECVTVSELYAHQ
>M28_Spy0209 N-acetylneuraminate transport system permease protein
MTKKKLTASDVLTTVILCILTILFIFPFYWIMTGAFKAQADTIMIPPQWW
PKAPTIENFKALVVQNPALKWLWNSVFISVATMFLVCGTSSLAGYALAKK
RFYGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGW
PFGVFLMKQFSENIPTELLESAKIDGCGEIRTFFNVAFPIVKPGFAALAI
FTFINTWNDYFMQLVMLTSRENLTISLGVATMQAEMATNYGLIMAGAAMA
AVPIVTVFLVFQKSFTQGITMGAVKG
>M28_Spy1652 transcription antiterminator, BglG family
MSPIAVKNDYGQLDSICLENENASFYTDIIGGDDMLSHELIRNYQLFSKY
KGHSLEAFESILKTSKRHILADIAKINDTLSLYQLPLIALDRQLVYPPDL
TEKDLLNRMLPTLDDYLFQDERLDMIIIYIMMAKEFISINHLESLLRLSR
NSVIADLNLVRDRVQAFQVTLAYNRQDGYFFEGEPLALRRLLESAVSSLL
QVTSGPWVFSYLLHELGLPDQTKVMAATLEELSRENHLTFISEKLRDLIY
FFCLLAHRPFSRNVRAEVVDTFPLASPAVETMVDQLLVNFPSLTEEKYLV
QSRLLGCIQGDLELVFQQPIYDIMEEIINSVAVNTGLSITDTPELRQNLY
SHLLPAYYRLYYDINLTNPLKEQIKQDYESLFYLVKRSLSPLEKQLGKPV
NEDEIAYFTIHFGRWLQAPKKRPSNQLVALSVCPNGISSSLMLEATLKEL
FPQLQFIRIHQLDKIKLLDPASFDLIFSTVAFDCVKPVYVTQALMGPVEK
MMLKKMVCDDFHLPLSEQFALDDLLSIIHKHTTITNKEGLVSDLSRYLFG
NHLTIEKGGLGLLDLLTADFIRQADAVSDWQEAIRLAAQPLLEHQMIETS
YIDGMIDSVNELGAYIVLAPKVAVPHAAPEKGTRQLGMSLLQLKEPVSFD
LKQEGDPDKQVQLIFVLSAVDSSSHLKALQELSLILDDDEHIEQLIEAKN
TEEIMSLISHMIEKGDESHD
>M28_Spy1062 PTS system, cellobiose-specific IIA component
MTEPSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEEAQHLLQEATNSL
NIAHKSQTHLLSQEAAGDAVELSLLMVHGQDHMMTALAFIDLAKELVTVY
DKMSAIQRGES
>M28_Spy0208 N-acetylneuraminate transport system permease protein
MFRTSGFFSMHMSNGHWKEAFLFRKVEQKKEVFQVNVNKLKMRETLISYA
FLAPVLVFFVIFVLIPMIMGFVTSFFNYSMTDFTFVGFANYARMFQDPIF
MKSLINTLIIVIGSVPVVVFFSLFVAAKTYDKNVVARSFYRAVFFLPVVT
GSVAVTVVWKWIYDPMSGILNYVLKYAHVIEQNISWLGDKHWALLAIIAI
LLTTSVGQPIILYIAAMGNIDNSLMEAARVDGATEFQVFWNIKWPSLLPT
TLYIAVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGY
ANTMGVFLAVMIAIISFAQFKILGNDVEY
>M28_Spy0350 phosphoglycerate transporter protein
MFMEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLMSNTI
MVQNGWDKAQIATLLSCLTVSYGLAKFYMGALGDRVSLRKLFSISLGASA
LICILIGFFNSSMVVLGILLVLCGVVQGALAPASQAMIANYFPNKTRGGA
IAGWNISQNMGSALLPLTIALLTSMGLVVPANGNILLAFLIPGVLVFLFA
LCCWKLGGDNPESEGLDSLRTMYGDAGESAVASEEEKHNLSYWQLIWKYV
FCNPSLLLVAAVNVALYFVRFGIEDWMPIYLSQVANMSEAHIHFAISMLE
WVAIPGSLVFAWLAVRYPNKMAKIGAIGLFVLAAIVFVYERLTATGAPNY
FLLLVIAGILGSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVTAYLIGN
MGANWLMPILADGFGWFWSYIVVAALSAFSAVGYLILAKREEEIIKD
>M28_Spy0150 L-xylulose 5-phosphate 3-epimerase
MPSKMKSNVSGGNFMARPIGIYEKATPKQFTWRERLQFAKDLGFDFVEMS
VDESDARLARLEWTKEERLDLVKAIYETGIRIPTICFSGHRRYPLGSNDP
AIEAKSLKLMKQCIELAQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLR
QSCDWAEEAQVMLSIEIMDDPFINSIEKYLAVEKEIDSPYLFVYPDAGNV
SAWHNDLWSEFYNGHKSIAALHLKDTYAVTETSKGQFRDVPFGQGCVDWQ
ELFAVLKKTNYNGPFLIEMWSENCDTVEETKAAIKEAQDFLYPLIEKAGL
T
>M28_Spy1735 transcriptional regulator, DeoR family
MMNRLERIIQLVSQKKKIDVNSLSEQLEVSKVTIRKDLDKLESKGLLRRE
HGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCAL
LAEVLCQTKRNIKIITNSCFIANYIRQYSSCQIILLGGYYQPNSEVTVGP
LLKEMISLFHVNRVFVGTDGFNKDLGFMGKDMMRSEGVRYMADAAEEVVI
LTDSSKFSKTSLVHQLSLADVNRVITDQALDKQTQELLSSGGLVLDFVS
>M28_Spy0078 bis(5'-nucleosyl)-tetraphosphatase(asymmetrical)
MTECIFCHQLKANQLLTQSQYFKVVFDIDPIQKGHLLLISKDHYTSLTQL
PKEVRYDLIDLQAALVAKLEQHLPISGVTSVSNDKELMDEGTHFHLHLIP
RLTNDSFWESITINQENWDLTPFLKHL
>M28_Spy0480 integral membrane protein
MSAKFMSRIAIMSALCVVLRMVFSSLPNVQPVTAFLLSYLLYFGLAEAVL
VMMLCLFLSAFLLGFGPWVFWQVTCFVLVLLLWRFALYPLSQQFPKYQLG
YQAFLAALCGLLYGVLIDTCFAYLYSMPWWSYVLAGMPFNIAHALSTLVF
FPVVMMLFRRLIGEQKI
>M28_Spy1389 D-beta-hydroxybutyrate permease
MEIIGSLGVLIGVIVIIYLSVKEVNIIIAAPLATSLVILFNQMDPTTTLL
GKEPNQFMGALSTYILNYFAIFLLGSILAKLMETSGETTSIADYILKKVG
HDSPYKVLVAIFLISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLI
QVPLWLGIATFTMTILPGTPAIQNVIPIQYLDTSLTAAAIPSIVGSIGCV
TFGLFYMKYCLAKSMARGETYATYAFDNEIQVKTKNLPHFLASILPLLLL
IIIALTGSLFGNDFFKKNIIFIALLAAILTASWLFRQFIPNKIAVFNLGA
SSSIAPIFATASAVAFGAVVMIAPGFTFFSDLILNIPGNPLISLAVLTSS
MSAITGSSSGALGIVMPNFAQYYLDQGLNPEMIHRVATIASNIFTIVPQS
GVFLTFLALTGLNHKNAFKETFITVSVSTFIAQVIMIAFDLFS
>M28_Spy1419 transaldolase
MKFFLDTANVAAIKAINELGVVDGVTTNPTIISREGRDFETVIKEICDIV
DGPISAEVTGLTADAMVEEARSIAKWHDNVVVKIPMTTEGLKATNILSKE
GIKTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGTDAYQLISDLREI
IDLYDFQAEIIAASIRTTAHVEAVAKLGAHIATIPDPLFAKMTQHPLTTN
GLKTFMEDWASFKK
>M28_Spy1064 transcription antiterminator, BglG family
MLSKKELAIITFLIHHKEQFVSSATLAEVIGMSDRTVRKYLKELISSLPE
HGAHIISKQGRGYCLEIDHSMAFDIFWQESVTSKKRLADVTQVEESVDRE
DYVLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEI
THQHIQIRGKEEDIRHFIMDYFFVTSFDNTLSTMVGNTFLEGINFAEIMI
IVLDECRDAKLKLSDFVMNNLVLHIALMVQRIRSGCPLELFSIPIAIRQS
DEYQVALRILYRVEEVMGIRFPKEEANYIALHLKVKHSVGKHWQDDNTDE
KLQDHLKACIAKISQLTGMTLETDTNLFQGLLAHMMPLTTRLENHIQLTN
PLTEEIKSQYPEIFTLTKQTFSDLLVCQKNDVSDDEWAYISLHLMAAIER
YSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEER
LKTVDLIISSISLANLMFLTPVITVSVFLSNQDIETIRQFIGEQEGIKKE
VSLPSQMSLAKAEQLLTGVFSPNRFLYLDEKISKEDLLLRMIACLDEAGT
ETFVEDFYHQMVLRENYSPVIYGEVLAFPHPANPMTYSEQVVVAICREPL
EWDKAHQAVHFVFLLSPSKGHNHRLKYVSPGLASFVNQVELQQALLEEPN
YSKFMTVFTPLIHD
>M28_Spy0504 galactose-6-phosphate isomerase LacB subunit
MKIALINENSQAAKNGIIYDALTSVTDKHGYQVFNYGMYGTEGESQLTYV
QNGLLASILLTTKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAY
LFSQINGGNALSIPFAKGFGWGAELNLTLIFERLFAEPMGGGYPKERAIP
EQRNARILSDLKKITYRDLLAIVKDIDQDFLKETISGAHFKEYFFANAEP
SELVAYLKSVLEQ
>M28_Spy1349 sugar-binding protein
MKKWQKIVCVTGTVLAASSLAACESKSASKDSDVKLLMYQVGDKPDNFDE
LMTIANKRIKEKTGATVDLQYIGWGDWDDKMSTIIASGENYDIAFANNYV
VNAQKGAFADLTTLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVY
AQQMLSFNKELVDKYGLDISNIKSYADAENVLKQFHEKEPNTAAFAIGQV
FSMSGDYDYPLTKTQPFAVKIDEGKPTIINQYEDESFKNNLRLMHKWYKE
GLIPTDAATNTEGYPLEGNTWFMREETQGPMDYGDTILTNAAGKDIVSRP
LTKPLKTTSQAQMANFVVSSVSKNKEKAVEVLSLLNSDPELLNGLVYGVE
GKAWEKIGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESVTDDMIAKRD
QSIKDAKESPILGFTVDTKVIKTELSNISNVMNRYKASINTGTVDPDEAL
PKLLADLKGAGWDKVQKEVQKQLDDFVAKDK
>M28_Spy1174 phosphoglucomutase
MSNMTYNEVYQEWLHNNDLSDDIKADLAAIKDNEAEIQDRFYKTLEFGTA
GLRGKLGAGTNRMNTYMVGKAAQALANTIIDHGPEAVKKGIAVSYDVRYQ
SRTFAELTCSIMAANGIKAYLYKGIRPTPMCSYAIRALGCISGVMITASH
NPQAYNGYKAYWQEGSQILDDIADQIAQHMAALTQYEEIKQMPFEKALDS
GLVTYIDESIEEAYKKEVLGLTINDTDIDKSVRVVYTPLNGVGNLPVREV
LRRRGFENVYVVPEQEMPDPDFTTVGYPNPEVPKTFAYSEKLGKAVDADI
LIATDPDCDRVALEVKNAVGDYVFLNGNKIGALLSYYIFSQRFDLGNLPA
NPVLVKSIVTGDLSRAIASHYGIETVETLTGFKNICGKANEYDVTKQKNY
LFGYEESIGFCYGTFVRDKDAVSASMMIVEMAAYYKKKGQNLLDVLQTIY
ATFGYYNERQIALELEGIEGQKRIARIMEDFRQTPIASVAEMALDKTIDF
IDGYQDFPKQNCLKFYLDDGSWYALRPSGTEPKIKFYLYTIGQTQENSAT
KLDAIEAACRTKINQVN
>M28_Spy1651 PTS system, IIB component
MKKEMNHMIKIVTVCGNGIGSSLLLRMKVEAIASSLGIDVDAESCDSNAA
VGKGADLFVTVKEFKDIFPEDAKVCIVKSYTNRKKIEEDLVPVLKEMSGK
E
>M28_Spy0469 hypothetical protein
MPAPLKKHNSVEQDDSYQESQSKFRDFQEFNGQSAKLKELVFFARIASFS
LITVLFAFVLLVMNLAPMFAFLFASIISLGITSLFAKVIKSLLM
>M28_Spy1129 oxalate/formate antiporter
MEKTKRYIIATAGILLHLMLGSTYAWSVYRNPILQETGWDQAPVAFAFSL
AIFCLGLSAAFMGNLVEQYGPRLTGTVSAILYASGNMLTGLAIDRKEIWL
LYIGYGVIGGLGLGAGYITPISTIIKWFPDKRGMATGFAIMGFGFASLLT
SPIAQWLIETEGLVATFYLLGLIYLIVMLFASQLIIKPTAAEIAILDKKR
LQNNSYLIEGMTAKEALKTKSFYCLWVILFINITCGLGLISVVAPMAQDL
TGMSPEMSAIVVGAMGIFNGFGRLVWASLSDYIGRRVTVILLFLVSIIMT
ISLIFAHSSLIFMISIATLMTCYGAGFSLIPPYLSDLFGAKELATLHGYI
LTAWAIAALTGPMLLSITVEWTHNYLLTLCVFIVLYILGLMVALRLKK
>M28_Spy1492 phosphoglycerate mutase
MTKTRLYIARHGKTMFNTIGRAQGWSDTPLTKKGEEGIRELGLGLKDATI
PFKAAFSSDSGRTMQTIEIILRESENEFLPYTKDNRIREWCFGSLEGTYD
SELFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLRKR
IWEGFEAIALSIQNAGGGNALVVSHGMTIGTFMWLIDPDREKQYIDNGSV
TVVEFEDGQFTIKTIGDMSYRYRGREIIEAMSDEA
>M28_Spy1609 glycerate kinase
MTINRVLKDDNLLQYTEKEFIEDMKILVAIDSFKGSVTSPELNTSVAQAL
LSVDKQLVIETRAIADGGEGSLAALSQTVAGRWHQVKTIDLLRRPIKVAY
YRHAKQAFIESASIIGIDKITPNSVTYAQATSYGLGLAVKDAIQKGATQI
EIMLGGTGTSDGGKGFLESLNYDFMTGRSYLDTLASPVTLLGLTDVTNPY
HGPQGFAAVFGPQKGGSLSQIEETDQIASNFAKKVFYQKTIDLQTIPGSG
AAGGLGGAIVLLGGTLTSGFSRIAELLNLDNSLQSCDLVITGEGCLDTQS
QSGKVPVAIARMAKKYQVPTIALCGSVKIETGLAAEDFLAVFSIQQQPIS
LEAAIDKTTTLSNIKILVANLMLLIAQFNK
>M28_Spy0454 multidrug resistance protein B
MSHHQQTVSKQTIMAIIAIALIGFSGILSETSMNVTFPTLMSVYQLPLNS
LQWMTTIYLLAVAIMMTTSATLKKNVRERPLFFMATGLFTFGTILAVLTQ
SFAIMLLARIFQGIGTGLVMPQMFNIILERVPMHKVGLFMGFAGLIISLA
PAFGPTYGGFMISHFSWQWIFICILPVPLIAGILAYYYLEDSPVSEKVPF
DWLAFIALSISLTSALLAITSLENGSVNLYYLGLFILSFVLFLYKNLTAK
QPFLDIRILKIPSLTFGLIPFFVFQLINLGINFLTPNFIVMEKIANSSQA
GMVLLPGTLLGALLAPAFGKLYDQKGAKLSLYLGNALFSLSLIIMTLQTR
HFMLLPFTLLYILFTFGRNMGFNNSLATAIRELPAEKNADATAIFQMMQQ
FAGALGTAMASLIANSQPEFTSGVQSVYLLFTIFALLDFIFFFAMFYHLG
KKGLA
>M28_Spy0399 multidrug resistance protein B
MNWRQNLKVAWLGNFFTGASFSLVMPFMALYVENLGTPKELVEYYAGLAV
AVTALASALFAPVWGKLADRYGRKPMMLRASFVMTFTMGGLAIIPNVFWL
LILRLLTGVFAGYVPNATALIASQAPKEESGYALGTLATGVTAGALIGPL
LGGILAELLGIRQVFLLVGVILFLCSLMTAVYVKEEFKPIRRFEMIPTKV
ILKQVKSPQIMLGLFVTSMIIQISAQSVAPILSLYIRHLGQTHNLMFTSG
LVVSAMGFSSLFSSSYLGKLGDRFGNHRLLLAALCYSFIMYFSSALAQTS
FQLGVLRFAYGFGVGALMPSINSLLTKLTPKEGISRVFAYNQMFSNLGQV
IGPFIGSNVAVVLGYRSVFYVTSLIVFVNLIWSLIIFRKYIKVKDIV
>M28_Spy1350 sugar transport system permease protein
MEKKKKVEKVNVRTFDRKTNAIFNILIGLFAISCIIPFIFVIIISFTDES
YLINHGYSFFPDVWSTKAYQYIFQGAMSHRIMRSFGISVFITVVGTFINT
TMTSTYAYAISRPYFPYRRFFTVYALITMLFAPGMVANYLVVSNLLHLKD
TVWALILPMALGPFGILVMRTFFKKTVPDSIIESARMDGASEWMIFMKIV
LPLAVPGIATISLFSALTYWNDWFNALLYVQSENLYPMQYLLMKIQSNLQ
ALAQNAGMSAQMADSLASLPKESVRMAIVVIATLPIALTYPFFQKYFVGG
LTIGGVKE
>M28_Spy0824 ATP-NAD kinase
MMTQMNYTGKVKRVAIIANGKYQSKRVASKLFSVFKDDPDFYLSKKNPDI
VISIGGDGMLLSAFHMYEKELDKVRFVGIHTGHLGFYTDYRDFEVDKLID
NLRKDKGEQISYPILKVAITLDDGRVVKARALNEATVKRIEKTMVADVII
NHVKFESFRGDGISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNN
RVFRTLGSSIIIPKKDKIELVPKRLGIYTISIDNKTYQLKNVTKVEYFID
DEKIHFVSSPSHTSFWKRVKDAFIGEIDS
>M28_Spy0212 N-acetylmannosamine kinase
MKHYLAIDIGGTAIKYGLISETGDLLEKEEMATEAYKGGPSILEKVKGLV
KTYQDQMDLAGVAISSAGMVNPDKGEIFYAGPQIPNYAGTQFKKEIEETF
GLPCEVENDVNCAGLAEAISGSAKDYPVALCLTIGTGIGGCLLFNSQVFH
GSSHSACEVGYLHLSDGQFQDLASTTALVQEVALAYGDDISQWDGRRIFE
QAKAGDAICIAAISKQVDYLGQGIANICYVVNPNVVVLGGGIMVQKDYLA
DKLKTALDSYLVSSLAKKTQLKFASHGNNAGILGAYYHFKQKNERSCSFI
TLEKIENNLASS
>M28_Spy1731 PTS system, cellobiose-specific IIC component
MAKMNMQNIIKPIMTFVNMRGIIALKDGMLAILPLTVVGSLFLIAGQIPF
QGVNDAIASVFGADWTEPFMQVYHGTFAIMGLISCFAIGYSYAKNSDVEP
LPSGVLSLSAFFILLRSSYVPAEGEAIGDAISKVWFGGQGIIGAIVIGLT
VGAVYTTFIRRHIVIKMPDQVPQAIAKQFEAMIPAFVIFTLSMLVYIIAK
SVTGGGTFIEMIYDVIQVPLQGLTGSLYGALGIAFFISFLWWFGVHGQSV
VNGIVTALLLSNLDANKALMAAGELSLDKGAHIVTQQFLDSFLILSGSGI
TFGLVVAMIFAAKSKQYKALGKVAAFPALFNVNEPVVFGFPIVMNPVMFL
PFILVPVLAALTVYGAIAIGFMQPFAGVTLPWSTPAIISGFMVGGWQGAI
VQILILIMSTLVYFPFFKIQDNMAYQNEQASEES
>M28_Spy1733 PTS system, cellobiose-specific IIA component
MQVIVPDQIIMGLILNAGDAKQHIYQALKCAKEDDYATSEKEMALADDAL
LEAHNLQTQFLAQEASGNKSEITALFVHSQDHLMTTITEINLIKEIIDLR
KELATK
>M28_Spy1353 hypothetical protein
MPGPFVDVIVADASVKGIGHQLILELLEAMLVIANKQSLT
>M28_Spy1768 PTS system, trehalose-specific IIBC component
MGKFEQDAKSLLTAIGGKENIKAVTHCATRMRFVLNDNNKANVKEIEKIS
VVKGTFTNAGQFQVIIGNDVPVFYNDFTAVSGIEGVSKEAAKSAAKSNQN
ALQQVMTMLAEIFTPIIPAIIVGGLILGFRNILESVPFEFLGQQVEKGKL
VFDAAGDPVWNTIVRVSPFWSGVNHFLWLPGEAIFHFLPVGITWSVTRKM
GTTQILGTVLGICLVSPQLLNAYAVAGTPAAEIAKNWVWDFGFFTINRIG
YQAQVIPALLAGLSLAYLEIFWRKRIPEVVSMIFVPFLSLIPALILAHTV
LGPIGWTIGKGISFVVLAGLTGPVKWLFGAIFGALYAPLVITGLHHMTNA
IDTQLIADTATRTTGLWPMIALSNIAQGSAVFAYYLMNRHEEREAEISLP
AAISAYLGVTEPALFGVNVKYVYPFVAGMIGSGIAGLLSTTFNVQANSIG
VGGLPGFMAINVKYMIPFFICMVVAIVVPMFLAFFFRKSHIMTKTEDEAK
LPETPVSDAPVATAPHKTMQGTVITLTSPLTGEVKALSEAVDPVFAQGVM
GQGALLQPTEGVLVAPCDAEVSVLFPTKHAICLVTTEGLELLMHIGMDTV
NLDGQGFEALVKQGDQVKAGQTLIQFDIAAISEAGYATETPLVVTNQDAF
TVTVEGSLPRQIKANDKLAVAMKK
>M28_Spy1637 hypothetical membrane spanning protein
MSYKDLKEKRIMFDSKQNLAKSQWGFIVITAVMDLVVIVATLLAKTSFQR
YLVGGVAVILTSFLILLVWGLKTAKKLQTRLDSKEVLDSKVRDDQKLPRY
DERQKQILLKGYTIGFWFMIVAVWLSIFLHRFSERLVSASFLFTLALWGG
LAVQTTYCNLNGVSPFVDRRFGKQGILVGMIATGMSLITIGLAVREMMAG
QLKMGSFFKAGGSGSLMVLGITLLSMGASIFYRHYLDAKEADE
>M28_Spy1442 PTS system, galactose-specific IIC component
MMQPFLDIINKILGFPIQLGSGVVMLIVMTGLAMIFGVKFTKALEGGIKL
AIALTGIGAIIGILTGAFSESLQAFVKNTGISLNIIDVGWAPLATITWGS
PYTLYFLLVMLVVNIVMIVMKKTDTLDVDIFDIWHLSITGLLIMWYADHN
HLPVLVSLLIATVAVILVGVLKIINSDLMKPTFDDLLGTGSQSPMTSTHM
NYMMNPIIMVLDKIFDKVFPGLDKYDFDAAKLNKKIGFWGSKFFIGMALG
FVIGIMGDPHFTVESIKNWFGLGFTAGACLELFSLIGSWFIAAVEPLSQG
ITNFANARMHGRRFNIGLDWPFIAGRAEIWACANILAPIMLIEAVLLSKV
GNGILPLAGIIAMGMTPALLVVTRGRLIRMIIFGSLLLPLFLLSGTMIAP
FATELAKKVGAFPAGTSAGSLITHSTLEGPMEKIFGYVIGQATTGQIASI
ITLIIFVAIYLGLFAWYANQMKARNAEYAKTMK
>M28_Spy1351 sugar transport system permease protein
MIYCNYNVINTKGGWEMTRQTNKKTSFWKNVIKYRALLLMVLPGFIWFIF
FFYIPVLANVVAFKDFHYSAGGFMESLKESPWVGLANFKYLFASKDAWLI
TRNTIAYNVIFLLFNVFFAIVFAIIMSELRNKRTVKVYHTMSLLPYFLSW
VVIEYFVSAFLNTDKGFINQLLVGSGADPIKWYSNPTWWPLILLFMSGWK
GLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQIRNITIPQLLPMMSIL
LIINIGNIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALTATGDIGMA
SAASLYQSVVGTSILLVTNAIVRRMDPDAALF
>M28_Spy0795 polysaccharide deacetylase
MNNRHKRRQKRKAFTLINLILLFACILGLTLIFYLYQGSNKFGLSDVSQF
VPKISLFHHKKTAKKETTKLKKTHFDSSKSQKKAHSKLTWTKQETPVKIP
ILMYHAIHVMFPEETANANLIVNPDLFDQQLQKMKDEGYYFLSPEEVYRA
LSNNELPAKKVVWLTFDDSMIDFYNVAYPILKKYDAKATNNVITGLTEIG
SAANLTLKQMKEMKQFGMSFQDHTVNHPDLEQASPDVQTTEMKDSKDYLD
KQLNQNTIAIAYPSGRYNDTTLQIAARLNYKLGVTTNEGIASAANGLLSL
NRIRILPNMSPENLLQTMEP
>M28_Spy1358 alpha-mannosidase
MATKKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTDPDFHSFH
LDGQTIILDDYLQVRPEREPEIRQAIASGKLRIGPFYILQDDFLTSSESN
VRNMLIGKEDCDRWGASVPLGYFPDTFGNMGQTPQLMLKAGLQAAAFGRG
IRPTGFNNQVDTSEKYSSQFSEISWQGPDNSRILGLLFANWYSNGNEIPT
TEAEARLFWDKKLADAERFASTKHLLMMNGCDHQPVQLDVTKAIALANQL
YPDYEFVHSCFEDYLSDLANDLPDNLSTVQGEITSQETDGWYTLANTASA
RIYLKQANTRVSRQLENITEPLAAMAYEVTSTYPHDQLRYAWKTLTQNHP
HDSICGCSVDSVHREMINRFEKAYEVGHYLAKEAAQQIAGAVNTSDFPTD
SQPFLLFNTSGHSKTSVTELTLTWKKYYFGQRFPKEVYQEAQEYLAGLSQ
SFQVIDVSGNTISEADILDTSIAFDYDLPKRTFREPYFAIKVRLRLPITL
PAMSWKALALQLGNETAPSATVPLYDDSNQCLENEFLKVMIQTDGRLTIT
DKQSGVSYQDLLRFEDCGDIGNEYISRQPTHDQPFYADQGTTKLNIISNT
AQVAELEIQQTFAIPISADKLLQAEMEAVIDITERQARRSQEKAELTLTT
LIRMEKNNPRLQFTTRFDNQMTNHRLRVLFPTHLKTDHHLADSIFETVKR
PNHPDATFWKNPSNPQHQECFVSLFDGENGVTIGNYGLNEYEILPDTNTI
AITLLRSVGEMGDWGYFPTPEAQCLGKHSLSYSFESITKQTQFASYWRAQ
EGQVPILVEQTSHHKGSLRAEHSYVTGADDQVALTAFKRRLADNALITRS
YNLSNDKTCDFSLSLPNYNAKVTNLLEKDSKQSTPSQLGKAEILTLAWKK
Q
>M28_Spy0965 ABC transporter permease protein
MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSDGLFGVL
TNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVN
SHQIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKM
DYFINMLTVLAYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILV
ILISVAATYVHSHIFNINTSADSFPFTEQKTIYLLILEQFIEMIMFYLAT
NFIIKNKLNLQ
>M28_Spy0746 4-nitrophenylphosphatase
MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNNTTRTPE
MVQSMLANQFHVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSA
IAAAGYVEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLN
IPTERGLMPGAGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSE
AVMVGDNYLTDIMAGIQNDIATILVTTGFTRPEEVPTLPIQPDHVLSSLD
EWRL
>M28_Spy0147 PTS system, 3-keto-L-gulonate specific IIB component
MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEAKGLASG
YDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQEVL
>M28_Spy0207 N-acetylneuraminate-binding protein
MNMKKLASLVMLGASVLGLAACGGKSQKEAGASKSDTAKTEITWWAFPVF
TQEKAEDGVGTYEKKLIAAFEKANPEIKVKLETIDFTSGPEKITTAIEAG
TAPDVLFDAPGRIIQYGKNGKLADLNDLFTEEFTKDVNNDKLIQASKAGD
TAYMYPISSAPFYMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKG
YNPGSFFANGQGGDQGPRAFFANLYSSHITDDKVTKYTTDDANSIKAMTK
ISNWIKDGLMMNGSQYDGSADIQNFANGQTSFTILWAPAQPGIQAKLLEA
SKVDYLEIPFPSDDGKPELEYLVNGFAVFNNKDEQKVAASKTFIQFIADD
KEWGPKNVVRTGAFPVRTSYGDLYKDKRMEKIAEWTKFYSPYYNTIDGFA
EMRTLWFPMVQAVSNGDEKPEDALKAFTEKANKTIKKTQ
>M28_Spy1444 PTS system, galactose-specific IIA component
MFPNILFTEARTQPELFDLVASYLEKVGYVTQEYHQALVEREAVFPTGLK
VDLKDGSDILYAAIPHTETKYCLVDQVVYVRNSQALTFKHMINPEEDCLV
TDFFFIINSQNEGQTTILSNLITFFITKGNLSYLASLKDDKQAISNYLIE
KGVFQHD
>M28_Spy0206 N-acetylmannosamine-6-phosphate 2-epimerase
MPDKPTKEKLMEQLKGGIIVSCQALPGEPLYSETGGIMPLLAKAAQEAGA
VGIRANSVRDIKEIQAITDLPIIGIIKKDYPPQEPFITATMAEVDQLAAL
NIAVIAMDCTKRDRHDGLDIASFIRQVKEKYPNQLLMADISTFDEGLVAH
QAGIDFVGTTLSGYTPYSRQEAGPDVALIEALCKAGIAVIAEGKIHSPEE
AKKINDLGVAGIVVGGAITRPKEIAERFIEALKS
>M28_Spy1352 glucokinase
MRHDRLFYYNKGEHLMSLLCIDIGGTSLKFALCHNGQLSQQSSFPTPSSL
EKFYQLLDQEVARYSAYHFSGIAISSPGAINKEKGVIEGASAIPYIHHFK
IQEALEERLHYPISIENDANCAALAEATLGAGKGASSLAMLVLGTGVGGS
LVIDGKIYHGAHLFGGEFGFMIMNDRYQTFSQLGTVVNMAKRYSAIVNNG
KDYTGKAVLALAEQGDHLALKERQVFLQSLAIGIFNIQHAFDPQLILIGG
GVSQADFLLSAIEAELDKLYQAVEISDLRPQLAICHFKNEANLLGAAIDF
YQEHKEA
>M28_Spy0430 hypothetical cytosolic protein
MTFHITVNLDEISDKLDDSLKFLNRLSIKSCELRMINTKNIIQLSDAELI
NLKERLQKYNITPISIASPLFKWNIEENHLESKLDLYGISANVTLNEQWL
YVRKIIFIAKFLNIKYVRIFGGIGCSVDDFLNNELFLNLLKETEIIFLIE
NELGTSVSTADDLLKIGHFIDEKSIKNLKIWFDIANYYIVEPQVDKVIPK
LKKYIYYIHCKNYVNNDLGIHYVELGKGIIDYKTIIHEIHEHFIDLIFSL
EVHEKEIDKKAEVVRKSYLTLNEYINGG
>M28_Spy0481 hypothetical exported protein
MNKRFKTGFLALVAMLLVACSQGTKQTQTPSVPKADHHVRLVVKEDTNTI
DEKVSFGKGDTVLEILKDNYEVKEKDGFITAIDGIEQDTKANKYWLFKVN
GKMADKGADQITVKDGDSIEFYQEVFK
>M28_Spy1439 tagatose-6-phosphate kinase
MATGFSGGKLGDFIIHQLQEQGISNQFFKIKGETRNCIAVLHEGMQTKIL
EAGPYSDVDEAEVSLSHMSTIAKPFDVLTSQAVCLGD
>M28_Spy0930 myo-inositol-1(or 4)-monophosphatase
MRKDSFPLETKYAFARQIIKEAGLFIKSKMSEQLDIQVKTQFDDLVTNVD
QETQQLLMDRIHQTYPCDAILAEENDVRHPINQGNVWVIDPIDGTVNFIV
QGSQFAVMIAYYEQGIGQFGLIYDVMADQLLAGGGDFEVTLNGDKLPAYQ
EKPLERSLIGCNAGMFARNDRNLAHLIAKTLGVRVYGGAGICMVKVMKQE
LLAYFSFIQPWDYAAAKVLGDKLGYVLLTIDGYEPDFQTRQKIMFVPKCQ
LTRIASFLTKDSAVTLEDQ
>M28_Spy1678 PTS system, glucose-specific IIABC component
MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMINHESAF
LASLGNIIAQIGWAVIVNLHLLFALAIGGSWAKERAGGALASGLAFVLIN
RITGAFYGVSSAMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFV
GIIAGFVGATAYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILV
VVWPVIQSGINSFGMWIASSQDSAPILAPFLYGTLERLLLPFGLHHMLTI
PMNYTALGGTYEVMTGAAAGTKVFGQDPLWLAWVTDLVHLKGSDASAYSH
LMDSVTPARFKVGQMIGATGTLMGVALAMYRNVDADKKHTYKMMFISAAA
AVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNLRVHSFGNI
ELLTRTPMALKAGLGMDVINFVWVSILFAVIMYFIADMMIKKMHLATAGR
LGNYDADILGDHNTQATPTQVADSNSQVVQIINLLGGAGNIDDVDACMTR
LRVTVKDPAKIGAEDDWKKAGAMGLIQKGNGVQAVYGPKADILKSDIQDL
LDSGAVIPEVNMSQLTSKPTPAKDFKHVTEEVLSVADGMVLPITGVKDQV
FAAKMMGDGFAVEPTHGNIYAPVAGLVTSVFPTKHAFGLLTDNGLEVLVH
VGLDTVALNGVPFSVKVSEGQRVHAGDLLVVADLAAIKSAERETTIVVAF
TNTTEIQDVTLTSLGAQPAKTKVATVEL
>M28_Spy0149 3-keto-L-gulonate-6-phosphate decarboxylase
MTHLPNLQVALDHSDLQGAVKAAVAVGHEVDVIEAGTVCLLQVGSELVEV
LRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMEAAL
KAIKEERGGRGEIQIELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGE
TWGEKDLNKVKTLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITE
AEDPAAAARAFKDEIKRIWG
>M28_Spy0499 PTS system, N-acetylgalactosamine-specific IIC component
MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGMILGDLPTALS
MGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALAL
STPIAVVIQFLQTFAYTAFAGAPETAKKQLQKGNIRGFKFAANGTIWAFA
FMGLGLGLLGALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSV
MAKKELIPFVLIGYVCAAYLQIPTIGIAIIGIIFALNEFYNKPKQVDATT
VQGGQQDDWI
>M28_Spy1443 PTS system, galactose-specific IIB component
MIKILAACGAGVNSSHQIKDAIETQMSDRGYDVHCDAVMVKDITEELVSR
YDIFTPIAKTDLGFEMPIPTVEAGPILYRIPIMSEPVFAELERVIKENHL
Q
>M28_Spy1063 PTS system, cellobiose-specific IIB component
MIKTIKRRNLMKSIMLVCNAGMSTSMLVTKMQKAAQARDLEVSIWAVPVS
EADNEVAANSIDVLLLGPQVKFLLKDFKDKFEPDIKVDAINMADYGLMNG
EKVLETALAMMEE
>M28_Spy0498 agaD, PTS system, N-acetylgalactosamine-specific IID component
MNFTTNLNKSMQQLSKEANKMTGSNKLTKKDYLKTALRAFFLQNGFNYSN
YQGIGYANVIYPALKKHFGSDKKGLYQALEDNCEFYNTNPHFLPFITSLH
LVMLENDRPEEETRNIKMALMGPLAGIGDSLSQFCLAPLFSTIAASLASD
GLVLGPIFFFLAMNIILTAIKIGSGLYGYKVGTSFIDKLSEQMAIVSRMA
NIVGVTVIAGLAATSVKITVPITFAAGKVDAANTAQKFVTIQGMLDKIAP
ALLPALFTLLMYYLIKNKKWTTYKLVILTVIIGVIGSWLGILA
>M28_Spy0500 agaV, PTS system, N-acetylgalactosamine-specific IIB component
MTQPNIIMTRVDERLIHGQGQLWVKFLNCNTVIVANDAVSEDKIQQSLMK
TVIPSSIAIRFFSIQKVIDIIHKASPAQSIFIVVKDLQDAKRLVEGGVPI
TEINIGNIHKTDDKVAITQFISLGETDKSAIRCLAHDHHVVFNTKTTPAG
NSASDVDILDYI
>M28_Spy1046 amyA, alpha-amylase
MDILCLVTKRLFEKEKAMRELHIKTYKLLTKSAVLLGLISFPLTVSAADN
ASVTNKADFSTDTIYQIVTDRFNDGNTSNNGKTDVFDKNDLKKYHGGDWQ
GIIAKIKDGYLTDMGISAIWISSPVENIDSIDPSNGSAAYHGYWAKDFFK
TNQHFGTEADFQQLVKVAHQHHIKVVIDFAPNHTSTAEKEGTTFKEDGAL
YKNGKLVGKFSDDKDKIFNHESWTDFSTYENSIYHSMYGLADLNNINPKV
DQYMKEAIDKWLDLGVDGIRVDAVKHMSQGWQKNWLSHIYEKHNVFVFGE
WFSGHTDDDYDMTTFANNSGMGLLDFRFANAIRQLYTGFSTFTMRDFYKV
LENRDQVTNEVTDQVTFIDNHDMERFATKVANNQTAVNQAYALLLTSRGV
PNIYYGTEQYATGDKDPNNRGDMPSFNKESQAYKVISKLAPLRKQNQALA
YGTTEQRWISDHVLVFERKFGNHVALVAINRDQTNGYTITNAKTALPQNS
YKDKLEGLLGGQELIVGADGTISSFELGAGQVAVWTYEGEDKTPQLGDVD
ASVGIAGNKITISGQGFGNSKGQVTFGEISAEILSWSDTLITLKVPTVPA
NYYNISVTTADKQTSNSYQAFEVLTDKQIPVRLLINDFKTVPGEQLYLMG
DVFEMGANDAKNAVGPLFNNTQTIAKYPNWFFDTHLPINKEIAVKLVKKD
SIGNVLWTSPETYSIKTGHEAQTITIKK
>M28_Spy1047 amyB, neopullulanase
MEVEMNVAGMLHIPDSRYCFAISQKELVIRLRVAKEDRGITVNLVHGPKY
GYHEFQEELEMSVAYTDHTHAYYETTLTLDDVRLAYIFKIEEEGQTYYFS
EDGLTTSYDFSNGFYNFFQMPYINAVDVHQVIPWTKDAVFYQIFVDRFNR
GDWEKGDSYVNMGWLEKPTPKSFAGGDLKGITEKLDYLKDLGITVIYLTP
IFQSISNHKYDISDYYAIDPQFGTKYDLQELIDLAHQMGIKIILDAVFNH
ASSDAVEFQDVLRYGKESKFFDWFMTHDEHPSMDLVNYETFAGCNYMPKW
NTSNRDVQDYLIEIGRYWIKEFCIDGWRLDVSDEVSHDFWRRFRQAVKAE
KADAILIGENWHDAYPYLAGDQYDGIMNYAFTKACLDYFAFETMTSKQLA
EKLSNILMRNTWQVNRMNLNLLDSHDTHRFFTQVKGSKDKLLAALALLFI
FMGIPCLYYGTEVAMEGGYDPDSRRGFPWDDAERDKDFFSKVKAIIALRQ
QPALQEGAISIDYDEDCLILKRSLGEQSISLVLNNGESAYSIKEGGQILT
SNGVTKNKKQLLQDGYIVFSN
>M28_Spy0151 araD, L-ribulose-5-phosphate 4-epimerase
MAKNLQEMRERVCAANKSLPQHGLVKFTWGNVSEVCRELGRIVIKPSGVD
YDLLTPENMVVTDLDGNVVEGDLNPSSDLPTHVELYKAWPEVGGIVHTHS
TEAVGWAQAGRDIPFYGTTHADYFYGPVPCARSLTKAEVDGAYEQETGSV
ILEEFSKRGLDPMAVPGIVVRNHGPFTWGKTPEQAVYHSVVLEEVAKMNR
LTEQINPRVEPAPRYIMDKHYLRKHGPNAYYGQK
>M28_Spy0457 bglA, 6-phospho-beta-glucosidase
MGIFPKDFLWGGAVAANQVEGAFEADTKGLSVQDVLPNGGLGEWTDSPTS
DNLTLEAIDFYHRYKEDIALFAEMDFKVFRTSIAWSRIFPNGDDDQPNEA
GLQFYDDLFDELLNYGIEPLVTLSHYETPLHLAKAYNGWTDRRLIGFFER
FAQTVMERYKDKVKYWLTFNEVNSILHMPFTSGGIMTEKEKLSLQDLYQA
IHHELVASASVTKLAHEINPDVKVGCMILAMPAYPMTSDPRDILAAHAFE
NLNLLFSDIHVRGKYPSYIKSYFKENGIEIVFEDGDKELLAEHTVDFLSF
SYYMSVTQAHNPEAYTSGQGNILGGLSNPYLESSEWGWQIDPIGLRLVLN
QYYDRYQIPLFIVENGLGAKDQLVQTADGSMTVHDDYRIDYMSQHLVQVA
KAIEDGVEVMGYTAWGCIDCVSMSTAQLSKRYGFIYVDRNDDGTGQLTRY
KKKSFDWYRQVIQTNGRYLEDNFS
>M28_Spy1066 bglA.2, beta-glucosidase
MSKERTKDMKQRKHRYQFPDGFLWGSSTSGPQSEGTVPGDGKGPSNWDYW
FSIESAKFHHQIGPEKTSTFYENYKGDIALLKETGHTIFRTSIQWSRLIP
EGVGEVNPKAVTFYREVFQDIIAQGIKLIVNLYHFDLPYALQEKGGWENK
ATVWAYETYAKTCFELFGDLVNTWITFNEPIVPVECGYLGYYHYPCKVDA
KAAVQVAYNTQLASSLAVKACHKLHPDHKISIVLNMTPAYPRSDAPEDVK
AARIAELFQTKSFLDPSVLGVYPAELVSILEEADLLPQYSADELEVIKNN
TVDFLGVNYYQPLRVQAPSKSQQEGDPLILDIYFEPYDMPGKKVNPHRGW
EIYEPGLYDIALNLKEHYGNIEWLVTENGMGVEGEEAFLADGQIQDDYRI
TFIEDHLIQLHKALGEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLE
SQKRTIKKSGYWFKALSESNGFDK
>M28_Spy0879 citE, citrate lyase beta chain
MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKDTSRALV
HFALKTFDYSSVETVVRVNGLDSCGALDIEAVVLAGVNVIRLPKTETAQD
IVDVEAVIERVERENSIEVGRTRMMAAIESAEGVLNAREIAKASKRLIGI
ALGAEDYVTNMKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNN
TEGFQNEVRMIKQLGFDGKSVINPRQIPLVNEIYTPTEKEIDHSKQVIWA
IREAESKGSGVISLNGKMVDKPIVERAERVIALATAAGVLSEEDI
>M28_Spy0676 deoB, phosphopentomutase
MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISETAGLSV
PNMAKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIM
GLNITEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGS
RQMETGELIVYTSADPVLQIAAHEDIIPVEELYKICEYARSITLERPALL
GRIIARPYVGEPGNFTRTANRHDYAVSPFQDTVLNKLADAGVPTYAVGKI
NDIFNGSGITNDMGHNKSNSHGIDTLIKTLQLPEFTKGFSFTNLVDFDAN
FGHRRDPEGYRDCLHEFDNRLPEIIANMKEDDLLLITADHGNDPTYAGTD
HTREYIPLLAYSASFTGNGLIPQGHFADISATVAENFGVDIAMIGESFLG
HLK
>M28_Spy1669 dexB, glucan 1,6-alpha-glucosidase
MINRRRIMKKHWWHKATIYQIYPRSFKDTSGNGIGDLKGITSQLDYLQKL
GITAIWLSPVYQSPMDDNGYDISDYEAIADVFGDMADMDELLAAANERGI
KIIMDLVVNHTSDEHAWFVEARENPNSPERDFYIWRDEPNDLTSIFSGSA
WEYDNASGQYYLHLFSKRQPDLNWENEALRHKIYDMMNFWIAKGIGGFRM
DVIDLIGKVPDSEITGNGPRLHDYLKEMNQATFGNHDVMTVGETWGATPE
IARQYSRPENKELSMVFQFEHVGLQHKPDAPKWDYAEELDVPALKTIFSK
WQTELKLGEGWNSLFWNNHDLPRVLSIWGNDSTYREKSAKALAILLHLMR
GTPYIYQGEEIGMTNYPFKDLTEVNDIESLNYAKEAMGNGVSAARVMDSI
RKVGRDNARTPMQWSKDTHAGFSEAKETWLPVNPNYQDINVADALADPDS
IFYTYQKLIALRKEQDWLVEADYHLLPTADKVFAYQRQLGEETYVIVVNV
SDEEQVFAKDLTGAQVIITNTDVDTVFETKHLQPWDAFCLKLKA
>M28_Spy1767 dexS, trehalose-6-phosphate hydrolase
MTIDKKKVVYQIYPKSYKDTTGNGVGDLRGIIDKLPYLQELGIDMIWLNP
FYPSPQRDNGYDVSDYTAVNPDFGTMADFEDLVKAAKEHQIELMLDMVLN
HCSTDHEWFQKALAGDPYYQDFFILRDQPTDWVSKFGGNAWAPFGDTGKY
YLHLFDVTQADLNWRNPHVREELAKVVNFWRDKGVKGFRFDVINLIGKDE
ELVDCPVNDGKPAYTDRPITHTYLHDLNQASFGQDDSFMTVGEMSATTID
NCLLYTAPEREELSMAFNFHHLKVDYENGQKWTIMAFDFAALRDLFHAWG
EGMSQGNGWNALFYNNHDQPRALNRFVDVTHFRNEGATMLAASIHLSRGT
PYIYMGEEIGMLDPDFDSMDDYVDVESLNAYSSLLVSGKSAEEAFAIIKA
KSRDNARTPMQWDASEHAGFTTGKPWLEVGKSYRDINVETEKEGRIFPFY
QRLIALRKELPIIAEGDYRAAFKDSQAVYAFERHLGDQCLLVLNHFYAGE
VELELPPRYQHGQALISNYEKVSICEKVMLKPYQTLAILADN
>M28_Spy0535 eno, enolase
MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVE
LRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGT
PNKGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNII
NGGSHSDAPIAFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVT
AVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGENGIMIGFDCASSEFY
DKERKVYDYTKFEGEGAAVRTSAEQVDYLEELVNKYPIITIEDGMDENDW
DGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIKENAANSILIKVNQIGT
LTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLS
RTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK
>M28_Spy1597 fba, fructose-bisphosphate aldolase
MAIVSAEKFVQAARENGYAVGGFNTNNLEWTQAILRAAEAKQAPVLIQTS
MGAAKYMGGYKVCQSLITNLVESMGITVPVAIHLDHGHYEDALECIEVGY
TSIMFDGSHLPVEENLAKTAEVVKIAHAKGVSVEAEVGTIGGEEDGIIGK
GELAPIEDAKAMVETGIDFLAAGIGNIHGPYPENWEGLALDHLEKLTAAV
PGFPIVLHGGSGIPDDQIKEAIRLGVAKVNVNTESQIAFSNATREFARNY
EANEAEYDGKKLFDPRKFLAPGMKAVQGAVEERIDVFGSANKA
>M28_Spy0742 femD, phosphoglucosamine mutase
MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDT
RISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISA
SHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTL
VDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEI
AVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVD
ETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGIN
KAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAK
VMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAIANIIAKME
DEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCD
N
>M28_Spy0643 fruA, PTS system, fructose-specific IIABC component
MKIQDLLRKDIMILDLQAISKEVAIDEMITKLVEKDIVHDFDVFKKSIMT
REEQTSTGLGDGIAMPHSKNIVVDKPAVLFAKSNKGVDYKALDGQPTDLF
FMIAAPQGANDTHLAALAELSQYLLKDGFADKLRAAATPEAVIAVFDEAS
TAKEEVVAPTSGQDFIVAVTACPTGIAHTYMAEEALKKQAAEMGVAIKVE
TNGASGVANRLTAEDIQRAKGVIVAADKAVEMDRFDGKQFIARPVADGIK
KSQELISLILNNEGNTYHAKNGKSETAVSTEKTSLGGAFYKHLMGGVSQM
LPFVIGGGIMIALAFLLDNMLGVPNDQLGSLGSYHEIAAIFMNIGGAAFS
FMLPVLAGYIAYSIAEKPGLVAGFVAGAIASNGLAFGKVPFAAGGEVSLG
LTGVPSGFLGALVGGFLAGGVILALRKLLAGLPRSLEGVKSILLYPLLGV
LVTGFLMLFVNIPMAAINTALNDFLQGLSGSSAVLMGLLVGGMMAVDMGG
PVNKAAYVFGTGTLAATVANGGSVVMAAVMAGGMVPPLAVFVATLLFKDK
FTKEERESGLTNIVMGLSFITEGAIPFGAADPARAIPSFIAGSALTGALV
GLAGIKLMAPHGGIFVIALTSNPILYLVFVVIGALVSGILFGALRKKA
>M28_Spy0642 fruB, 1-phosphofructokinase
MIYTVTLNPSIDFIVRIDQINLGSVNRMASDDKFAGGKGINVSRILQRLD
IASTATGFLGGFTGRFIEESLSAEGVKTDFVKGDQDTRINVKIKSQEETE
INGQGPVISREQLEDLKTKLSQLTAEDTVVFAGSAPANLGNAVYKELFPL
VRQSGAQVVCDFEGQTLIDALTYNPLLVKPNNHELEAIFGTILTSLDDVE
TYARRLLEMGAQNVIISMAGDGALLVTKEATYFAKPIKGEVKNSVGAGDS
MVAGFTGEFMKSQNPIEALKWGVACGTATAFSDDLATIAFIKETYHKVEV
EKR
>M28_Spy0641 fruR, fructose repressor
MAKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHGGAELFH
SLQEELSNQEKSVKNSHIKKTIAQRASQFIYDNDVIFIDAGTTTEFLLPF
LQAKNLTVVTNSIHHAARLVELSIETIIVGGYVKQTTDASIGNVALEQIR
QMNFDKAFLGMNGIDDSYLTTPDMEEAVIKKAVLSNAKLAYILVDGTKIG
QVSFVKVAPINDVTIITLGGSASILKQIKEKAKVIEL
>M28_Spy1196 glcK, glucokinase
MSQKLLGIDLGGTTIKFGILTAAGEVQEKWAIETNILEGGKHIVPDIIAS
IKHRLDLYGLSSADFVGIGMGSPGAVDRDTNTVTGAFNLNWKETQEVGSV
VEKELGIPFAIDNDANVAALGERWVGAGENNPDVVFMTLGTGVGGGIIAD
GNLIHGVAGAGGEIGHMIVEPENGFACTCGSHGCLETVASATGVVKVARL
LAEAYEGDSAIKAAIDNGEGVTSKDIFMAAEAGDSFADSVVEKVGYYLGL
ASANISNILNPDSVVIGGGVSAAGEFLRSRIEKYFVTFTFPQVRYSTKIK
IAELGNDAGIIGAASLARQFITK
>M28_Spy1036 glgP, glycogen phosphorylase
MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNTAKRKVYY
ISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNG
GLGRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNFWIE
DDSWLVPTDISYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVD
YGLIKDGISFDKTQIAKNLTLFLYPDDSDKNGELLRIYQQYFMVSNAAQL
IIDEAIERGSNLHDLADYAYVQINDTHPSMVIPELIRLLTEKHGFDFDEA
VAVVKNMVGYTNHTILAEALEKWPTAYLNEVVPHLVTIIEKLDALVRSEV
SDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSELKAFYDLY
PEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMAFA
DDKAVHAKLAEIKFNNKLALKRYLKDNKGIELDEHSIIDTQIKRFHEYKR
QQMNALYVIHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCL
SELINNDPEVSPYLNVHLVENYNVTVAEHLIPATDISEQISLASKEASGT
GNMKFMLNGALTLGTMDGANVEIAELAGMENIYTFGKDSDTIINLYATAS
YVAKDYYDNHPAIKAAVNFIISPELLAFGNEERLDRLYKELISKDWFMTL
IDLEEYIEVKEKMLADYEDQDLWMTKVVHNIAKAGFFSSDRTIEQYNEDI
WHSR
>M28_Spy1422 glpF, glycerol uptake facilitator protein
MDIFGEFLGTALLVLLGNGVVAGVVLPKTKTHASGWIVIATGWGIAVAVA
VFISGKVAPAHLNPAVSLAFAMSGTIAWSTAIAYSLAQLLGAMVGSTLVF
LQFRPHYLAAESQADILGTFATGPAIRDTSSNLLSEIFGTFVLMLGILAF
GLYDMPAGLGTLCVGTLVIGIGLSLGGTTGYAINPARDLGPRLVHAILPL
NNKGDSDWSYAWIPVVGPIIGAALAVLLFQVMS
>M28_Spy1561 glpF.2, aquaporin
MIILFIILLPLHSSISLLKWYLLYFIIWRKPENMEMTWTVKYITEFIATA
FLIILGNGAVANVDLKGTKGHNSGWLVIAFGYGLGVMMPALMFGNVSGNH
INPAFTVGLAVSGLFPWAHVLQYVVAQLLGAIFGQLVVVMVYKPYFMKTE
NPNHVLGSFSTISSLDNGQKDSHKVSYINGFLNEFVGSFVLFFGALALTK
NYFGVELVGKLIEAGYDQTTAATQISPYVTGSLAVAHIGIGFLVMVLVTS
LGGPTGPALNPARDFGPRLLHHFLPKSVLGQAKGDSKWWYAWVPVVAPIL
AAIVAVAAFKYLYIR
>M28_Spy1158 gpmA, phosphoglycerate mutase
MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEF
DLAFTSVLTRAIKTTNLALENAGQLWVPTEKSWRLNERHYGALTGKNKAE
AAEQFGDEQVHIWRRSYDVLPPAMAKDDEYSAHKDRRYADLDPALIPDAE
NLKVTLERAMPYWEEKIAPALLDGKNVFVGAHGNSIRALVKHIKGLSDDE
IMDVEIPNFPPLVFELDEKLNIVKEYYLGGE
>M28_Spy1461 hit, bis(5'-nucleosyl)-tetraphosphatase(asymmetrical)
MENCIFCSIIQGDIPSSKVYEDEQVLAFLDISQTTKGHTLVIPKQHVRNL
LEMTAETASHLFARIPKIARAIQLATGATAMNIINNNEALAGQTVFHAHV
HLVPRYNEKDGISIQYTTHEPNFPVLEKLARQINQEVSS
>M28_Spy0506 kgdA, 4-hydroxy-2-oxoglutarate aldolase
MSRGDDMGKIEILTKLKANRLVLVVRGESSEEALACSLASIEGGIKTIEV
TYTNPFASEVIGQLAERFKEDPEVLIGAGTVLDDVTARQAILAGAQFIVG
PNFNRAVALICHGYSIPYLPGCMTVNEVVTALESGVDMVKIFPGSTVGIS
FIRAIKSPLPQVEVMVTGGVSSDNLKDWLAAGVDVLGIGGEFNQLASQKQ
YNLITKKAAHYIKSLRQ
>M28_Spy1441 lacA.1, galactose-6-phosphate isomerase LacA subunit
MAIILGADAHGNALKELIKSFLQEEGYDIIDVTDINSDFIDNTLAVAKAV
NEAEGRLGIMVDAYGAGPFMVATKLKGMVAAEVSDERSAYMTRGHNNARM
ITIGAEIVGPELAKNIVKGFVTGPYDGGRHQIRVDMLNKMA
>M28_Spy1628 lacA.2, galactose-6-phosphate isomerase LacA subunit
MAIIIGADKAGQELKEVIKDYLKEGKYEVVDVSENEVRDFVDTTLAVAKE
VNASEDNLGIVIDAYGVGSFMVATKIKGMVAAEVSDERSAYMTRGHNNAR
IITLGSEISAPGIAKNIIKGFVEGKYDGGRHQVRVDMLNKMC
>M28_Spy1440 lacB.1, galactose-6-phosphate isomerase LacB subunit
MMKIAIGCDHIVTNEKMAVSDFLKSKGYDVIDCGTYDHTRTHYPIFGKKV
GEAVVNGQADLGVCICGTGVGINNAVNKVPGIRSALVRDMTTALYAKEEL
NANVIGFGGKITGELLMCDIIDAFIKAEYKETEENKKLIAKIAHLESHHA
NQEDPDFFTEFLEKWDRGEYHD
>M28_Spy1627 lacB.2, galactose-6-phosphate isomerase LacB subunit
MKIAVGCDHIVTYEKIAVVDYLKSQGHEIIDCGTYDNVRTHYPIFGKKVG
EAVASGEAELGVVICGTGVGITNAVNKVPGIRAALVRDMTSAIYSKEELN
ANVIGFGGKIIGGLLMNDIIDAFLAAEYKPTEENKKWIEKMDSLQHASQD
QNNPHFFDEFLEKWDRGEYHD
>M28_Spy1626 lacC.2, tagatose-6-phosphate kinase
MILTVTLNPAIDVSYPLNELKCDTVNRVVDVTKTPGGKGLNVSRVLNDFG
ETVKATGCIGGESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTE
ILEKGPLLSVDEIDGFTHHFKYLLNDVDVVTLSGSLPAGMPDDYYQKLIK
IANLNGKKTVLDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTKDF
EALKEVLQDELFEGIEWIIVSLGADGVFAKHKDTFYNVDIPKIKIVSAVG
SGDSTVAGIASGLANDEDDRALLTKANVLGMLNAQEKTTGHVNMANYDKL
YQSIKVKEV
>M28_Spy1438 lacD.1, tagatose-bisphosphate aldolase
MTITANKRHYLEKVSHQGIISALAFDQRGALKQMMAAHQEGEATVTQIET
LKVLVSEELTPYASSILLDPEYGLLATKVRANQTGLLLAYEKTGYDATTT
SRLPDCLVEWSVKRLKAAGADAIKFLLYYDVDGDEQINLQKQAYIERIGS
ECTAEDIPFFLELLSYDERISDNNSAAYAKLKPHKVNGAMSVFSDKRFGV
DVLKVEVPVNMAYVEGFTEGEVHYSQAEAIKAFQDQEAASHLPYIYLSAG
VSAKLFQETLYFAAAAGAQFSGVLCGRATWAGSVPVYITKGEDEARKWLC
TEGFQNIDELNRVLEETASPWTEKI
>M28_Spy1625 lacD.2, tagatose-bisphosphate aldolase
MTITLTENKRKSMEKLSIDGVISALAFDQRGALKRMMAQHQTKEPTVEQI
EELKSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDAT
TTSRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERI
GSECRAEDIPFYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSEERF
GVDVLKVEVPVNMKFVESFADGEVLFTKEEAAQAFRDQEASTDLPYIYLS
AGVSAKLFQDTLVFAAESGAKFNGVLCGRATWAGSVKVYIEEGPQAAREW
LRTEGFKNIDELNKVLDKTASPWTEKM
>M28_Spy1623 lacE, PTS system, lactose-specific IIBC component
MNGLIAQIEKGKPFFEKISRNIYLRAIRDGFIAGMQVILFSSIFILIAYV
PNAWGFHWSKDIENLLMTPYNYSMGILGLFVAGTTAKALTDSMNRSLPST
NQINFISTMLAAIVGFLLMAANPAKDGGFLTGFMGTKGLLTAFIAAFITV
NVYKTCVKNNVTIRMPEEVPPNISQVFKDLIPFTLSVVLLYVIELIVHTT
LGVNVAESIGKLLAPLFQAADGYVGITIIFGAFAFFWFVGIHGPSIVEPA
IAAITYANAETNLQLLQAGEHADKILTSGTQMFIVTMGGTGATLVVPFMF
MWLTKSKRNKAIGRASVVPTFFGVNEPILFGAPLVLNPIFFIPFILAPIV
NVWIFKFFIDTLGMNSFTANLPWTTPAPLGLILGTNFQVLAFILAALLIV
VDVIIYYPFLKVYDEQILAEEAAGTNSSDALKEKVAANFDTKKADAILEK
SAAKETKEITDQTNVLVLCAGGGTSGLLANALNKAAKEYGAPVTAAAGSY
GAHREILPQYQLVILAPQVASNYEDMKVETDKLDIKLAKTEGAQYIKLTR
DGQGALDFVKEQMEK
>M28_Spy1624 lacF, PTS system, lactose-specific IIA component
MNREETTLLGFEIVAYAGDARSKFLEALKAAQEGDYAKAEELIAAGSDCL
NDAHNAQTSLLQKEAAGDDLAYSVTLMHGQDHLMTTILLQDLMKHMIELY
KRGAK
>M28_Spy1622 lacG, 6-phospho-beta-galactosidase
MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWYTAEPAS
DFYNRYPVDLKLSEEFGVNGIRISIAWSRIFPTGKGEVNPKGVEYYHNLF
AECHKRHVEPFVTLHHFDTPEALHSDGDFLNRENIEHFVNYAEFCFKEFS
EVNYWTTFNEIGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAV
KLFKDSGYSGEIGVVHALPTKYPFDANNPDDVRAAELEDIIHNKFILDAT
YLGKYSDKTMEGVNHILEVNGGELDLREEDFAALDAAKDLNDFLGINYYM
SDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRRKAPVDVPKTDWDWIIF
PQGLYDQIMRVKADYPNYKKIYITENGLGYKDEFVDNTVYDDGRIDYVKK
HLEVISDAISDGANVKGYFMWSLMDVFSWSNGYEKRYGLFYVDFETQERY
PKKSAYWYKKVAETQVIE
>M28_Spy1445 lacR.1, lactose phosphotransferase system repressor
MLKRERLLKITEIVNEQGIVTVNDIIQTLNVSDMTVRRDLDELEKAGKLI
RIHGGAQSITMPNKKERSNIEKQTVQTKEKWELASYATQLVNDGETIFIG
PGTTLECFAEQLKNRQIRIVTNSLPVFNILQDSETIDLILIGGEYRSITG
AFVGSLASQNISSLKFAKAFISCNGIYKNDIATYSETEGEIQKLAFNNSI
EKYLLVDNQKFNAYDFFIFYHLNNIDAVVTDSQITEDVIERYSQFTQLLV
AHENKE
>M28_Spy1629 lacR.2, lactose phosphotransferase system repressor
MKKKERHEKILDILKVDGFIKVKDIIDEMNISDMTARRDLDTLADKGLLI
RTHGGAQYLDYSSAKDEGHEKTHTEKKVLQTTEKKQIAQRAKNIIKDGET
VFIGPGTTLEHLAVELKNRNIRVITNSLPVFLILHPSTTIDLILIGGECR
EITGAFVGAIAINNLESLTFSKAFVSANAVYNNSIATYSDLEGEVQRVAL
NNAVEKILLVDSTKFESYDFYNFYQLDQVDLIVTDKNVTTDIIEKYKKFS
KIIIADK
>M28_Spy1345 lacZ, beta-galactosidase
MVYRQKSSEIVTRTITKPSRATSNVKQEIDMTPDSKEQTVTGYQYHYIDQ
EGRKQPFNQGWRFLMADVACAQDPSFDDSNWQVIHLPHDFSLTQPYTRNG
EAESAYKLGGVGWYRHYLVLDEVLAGCHVAITFEGSYMETEIYVNGQFIG
KHLNGYQEFTYDISDVVTFGAENLLAVRVENKVPSSRWYSGSGLYREVSL
SVLPQLHFVADQVAMTLADTAVQEKGQQKVDLRFALNQSIQTCHYQLSLC
LWEQSHCSKDKKLLYQETEVPLADLAFQRQYGLTLSLEELQLWSPDNPHL
YDLELTLYYQGQVIDCFCLETGFRQLTFMANQGLFVNGRAVKLKGVCLHH
DQGGLGACAYEDALARQLVLLKDMGANTIRSTHNPSSPKLRQLANRLGFF
VIEEAFDTWTYAKNGNVNDFSNYFHQTIGTENASYLQRVRSPETSWAQYS
IEAMVWSAKNDPSVLMWSIGNELMEGFSADVSHYPELTRQMCQWIAAIDT
SRPITFGDNKLKEADFCWHEEVSQMATLLSQLDHPQGLIGLNYANGKDYD
KLHEEHSDWLLYGSETASAITSRAYYKETKKVLDSGYHLTSYDHAKVDWG
AFASQAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSGVVGLWPSPKN
AYFGILDTAGFPKDSYYFYQSQWAQGQTTLHLLPVWQKDQLCFDEQGLVE
VVVYSNAASVQLMFEDEQGNVTDYGRKAFHTYSTPTGHTYQLYQGADAAK
NPHENLYLTWRVPYQKGLLRAVAYDISGKSIPKTSGRSQVRTYGSVAKLS
WKAFEAPIDAPWELLYLDLSLLDSRGELVSHAQDWLKVQVEGPAHLLALD
NGNPTDHTPYQEPLRQAYGGKLLAILALTGEAGHIKVTAKVSQQLSSVFQ
TQVACRAPKEHLVTLPLEKYQFKKSRLTSQQEIGQSCLKTTQFLSVLENK
DTQQKAGKVSTPHILITSYQHYLSLPLQVCSQAFDFKKGDDIFLPQWLQV
KDAQGSFVKKAFPMTWYLKEKIFAKPILVTGYVSCFGQSIPVEARLNLAQ
ASKRRHQDLSLVAKQSLATSQKRLTYCYQYDTVQAIGAISLQNHTDTSLS
VSVAISYGSQSSIKQETLMLADSHLSQLEEVIFFDDILTVLYLVVTLEVI
EGPDLTEDSIQIGLWDLA
>M28_Spy1787 lmrP, multidrug resistance protein B
MQEFLNLPKQIQLRQLVRFVTITLGSSIFPFMAMYYTTYFGTFWTGLLMM
ITSLMGFVGTLYGGHLSDALGRKKVIMIGSVGTTLGWFLTILANLPNAAI
PWLTFVGILLVEIASNFYGPAYEAMLIDLTDESNRRFVYTINYWFINIAV
MFGAGLSGLFYDHHFLALLVALLLVNVLCFGVAYYYFDETRPETHAFDHG
KGLLASFQNYRQVFHDRAFVLFTLGAIFSGSIWMQMDNYVPVHLKLYFQP
TAVLGFQVTSSKMLSLMVLTNTLLIVLFMTVVNKLTEKWKLLPQLVVGSL
LFTLGMLLAFTFTQFYAIWLSVVLLTFGEMINVPASQVLRADMMDHSQIG
SYTGFVSMAQPLGAILASLLVSVSHFTGPLGVQCLFVVIALLGIYFTVVS
AKMKKV
>M28_Spy1045 malC, maltose transport system permease protein
MVDNQRQQKPNKAMWLSVIPGLGQLYNKQIVKGGVLLVVFFLELLEIVVL
GIPALTGFYSLGSVPMQDHSLFMLIKGAMQLITLVLFGIFHLVAMRDAKL
VAHQMNEGKKVPVTAKETLEAIYEKGFPYLLIIPAYLAMAFAIIFPVLVT
LLIAFTNYDFRHIPPYRLLDWVGLKNFLNILELSTFKTAFTSVLSWTLIW
TLAATSLQIVIGIATAVIANQSFIRGKRLFGVIFLLPWAVPAFISIMSFG
NFFNDSIGAMNVQVLPFIEKFLPFVDFGIVSWKTDPFWTKVAVIMVQGWL
GFPYIYILVSGILQAIPADLYEAATVDGATVLQKFRHITMPMIFAVAAPT
FISQYTFNFNNFSIIYLFNNGGPGTVGGGAGTTDILISWIYKLTTQTSPQ
FSMASAVTLIISVIVISVSLITFKKFKAFDMEERS
>M28_Spy1044 malD, maltodextrin transport system permease protein
MRKTYVSISMKRKRFFTQLLTYLYLISLVIVILFPILVTVSSAFRPGNTT
AFSFHFDGPWTLSNFKTLFQDTLYLRWYWNTLIVAFFTMLIQVTVITLTG
YAYSRYNFFGRKKSLIFFLVVQMVPTMAALTAYFVMAWLFNALNQYWFLI
LIYVGGGIPMNAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVLPLVR
PMIAVQSLWAFMGPFGDFMLAKFLLRAQENYTVAVGLQSFITNDARNPKV
TLFAAGAILIAVPISVLFFFLQKNFVSGLTSGGTKG
>M28_Spy1039 malE, maltose/maltodextrin-binding protein
MKSWQKVIVGGASLTLASTLLVGCGSGSKDKKEAGADSKTIKLWVPTGSK
KSYADTIAKFEKDSGYTVKVVESEDPKAQEKIKKDASTAADVFSLPHDQL
GQLVESGTIQEVPEKYNKEIAATSTDQALVGAQYKGKTYAFPFGIESQIL
FYNKSKLPAEDVTSYDTITTKATFGGTFKQANTYATGPLFMSVGNTLFGE
NGEDVKGTNWGNEKGAAVLKWIADQASNKGFVSLDANNVMSKFGDGSVAS
FESGPWDYEAAQKAIGKENLGVAIYPKVTIGGETVQQKAFLGVKLYAVNQ
APAKGDTKRIAASYKLASYLTNAESQENQFKTRNIVPANKEVQSSEAVQS
NELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDAFNGKIKESDY
LTKLQQFDKDIAATK
>M28_Spy1040 malF, maltose transport system permease protein
MTQSNFTPNISVIEALKRGSWDIKLSSIIMGFANFANKQFIKGILFLISE
LIFLVAFVSQIIPAIRGLVTLGTQTQGMTTKTIDGINIQVAVDGDNSMLM
LIFGLASLIFCLVFAYIYWCNLKSARNLYLFKQKGQKIPNFKEDLATLTN
GRFHMTLMAIPLIGVLLFTILPLIYMICLAFTNFDHNHLPPKSLFDWVGL
ANFGNVLSGRMAGTFFPIFSWTLIWAVFATVTNFFFGIILALLINAKGLK
WKKMWRTIFVITIAVPQFISLLIMRNLLNDEGPLNALLNKIGLINGSLPF
LSDPLWAKFSIIFVNMWIGIPFTMLIATGIIMNLPSEQIEAAEIDGASKF
QVFKSITFPQILLIMTPNLIQQFIGNINNFNVIYLLTGGGPTNSEYYQAG
TTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
AAK
>M28_Spy1041 malG, maltose transport system permease protein
MKNKRRFQLGLVYATLIILSIIWLFPIAWVILTSFRSEGTAYVNYFIPKT
FTLNHYINLFTNETFPFGKWFMNTLIVATFTCIISTFITVAIAYSLSRIK
FKFRNGFLKLALILNMFPGFMSMIAIYYILKALGLTQTLTALVLVYSSGA
ALGFYIAKGFFDTIPYSLDESAMIDGATRMDIFFKITLPLAKPIIVYTAL
LAFMGPWIDFIFAQVILGDATSKYTVAIGLFSMLQPDTINNWFMAFTAGS
VLIAVPITLLFMFMQKYYVEGITGGSVK
>M28_Spy1037 malM, 4-alpha-glucanotransferase
MNKRASGILMHISSLPGKFGIGTFGKSAFEFVDFLAETKQTYWQILPLTT
TSFGDSPYQSFSAIAGNTHFIDFELLVDDELLEAADLCDITFGTNPEAVD
YAQLFQVRRPLLEKAVRAFVAEQENVCKLEAFETASSWLTDFAEFMALKE
YFNNKALQDWDDETVIKRQEDSLNNYRELLAKKITYHKVCQYFFYQQWSA
LKTYANHKGIEIIGDMPIYVSADSVEVWTMPELFKVDSDKKPLFIAGVPA
DGFSEDGQLWGNPTYNWSAHEKSNFAWWIYRIQESFKLYDQLRIDHFKGF
SDFWEIPAGDKTARNGHWASAPGIALFSAVREALGELPIIAENLGYIDEK
AEQLLASTGFPGMKILEFGLFDITSQSIDLPHYYDRNCVAYTGTHDNEVV
NGWYDNLSEEQVHFVNNYLHKHADESITKAMLRTIFASVCDTAILCIQDL
LDKDGKSRMNMPNTIGGNWQWRMLDGELNQDHKDYLIYLTDLYGRAR
>M28_Spy1048 malX, maltose/maltodextrin-binding protein
MFKKKPFREEHVMSWNWKKASVLGTLSLASVLPLTACVSGGGKGVKETDG
KTIVVSVDEGYVDYIKSIKGEFEKEHKVTVKVKKEGMMDTLDKLSTDGPT
GASPDVFLAPFDRVGGLGTEGQISEVTLGNSKEFDDTVKKLVTIDGKTYG
APDVIETLVTYYNKDLVPQAPKSFTELEVLQKDSKFAFASEPGKSVGFLA
KWTDFYYGYGLIAGYGGYIFGDKGTKPSDLGLGNDGTVEGLNYAKQWYGT
WPQGMQDTKKAGDFITEQFISKKAGVIIDGPWAASSFKDAGVNFGVMEIP
TLTNGKKYQPFAGGKAWVISNYSKGKTTAQKFLDYVTNAENQKRFYDKTQ
EIPANLTARNYASKEGNELTKAVISQFESAQPMPNIPEMAEVWEPGANMF
FNVASGKEEASKAAKEAAKTIKEAIEQKYAE
>M28_Spy1468 manL, PTS system, mannose-specific IIAB component
MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDDLYGHFN
NAIQQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPML
IQAYTERLMDAGAGVEQVAANIIKESKDGIKALPEDLNPVEETAATEKVV
NALQGAIPAGTVIGDGKLKINLARVDTRLLHGQVATAWTPASKADRIIVA
SDEVAQDDLRKQLIKQAAPGGVKANVVPISKLIEASKDPRFGNTHALILF
QTPQDALRAVEGGVEINELNVGSMAHSTGKTMVNNVLSMDKEDVATFEKL
RDLGVTFDVRKVPNDSKKNLFELIQKANIK
>M28_Spy1469 manM, PTS system, mannose-specific IIC component
MSDISIISAILVVIIAFFAGLEGILDQFQMHQPLVACTLIGLVTGHLEAG
VILGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKSGDFTQKGITFA
YSTAIPLAVAGLFLTMIVRTLSTALVHAGDKAATEGNFAGIERFHFIALL
LQGLRIAVPAALLVAVPTSAVQSVLNAMPNWLNEGMQIGGAMVVAVGYAM
VINMMATREVWPFFALGFALAAISQLTLIAMGVIGVAIAFIYLNLSKKGG
NGGNAAGSADPIGDILEDY
>M28_Spy1470 manN, PTS system, mannose-specific IID component
MTEQIKLTKSDRQRVWWRSQFLQGSWNYERMQNMGWAYALIPALKKLYTS
PEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTPIDDKAIQGV
KIGMMGPLAGIGDPVFWFTVRPILGALGASLASTGNIVGPLLFFFGWNLI
RMAFLWYTQEFGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRW
VSINFTIDLPGKQLSDGAYVVFPDGAVKGAELKTILANAIGGMSLDKVQA
QTLQGQLDSLIPGLAGLLLTFLCMWLLKKKVSPIAIIIGLFAFGILAHLA
GIM
>M28_Spy0438 mefE, macrolide-efflux protein
MYSKVIYRIGDVMFDFANNTFLAGLNPASLSLVAVYQSLESVIGVLFNLF
GGVIADSFKRKKIIITTNILCGTACLVLSFLTKEQWLVYAIVLTNVILAF
MSAFSSPSYKAFTKEIVKKDSISQLNSLLETTSTVIKVTVPMVAIFLYKL
LGIHGVLLLDGLSFLIAALLISFILPVNDEVVIKEKVTIREIFNDLKIGF
KYVYSHKSIFIITVLSALVNFFLAAYNLLLPYSNQMFGEISTGLYGTFLT
AEAIGGFIGAILSGFVNKELSSMRLILFLSLSGLMLMLAPPFYIMFHNAI
ILALSPALFSLFLSIFNIQFFSLVQKDVDNDFLGRVFGIIFTITILFMPI
GTGFFSVALNPNNSFNLFIIGSCITILSLVFRILFKKYNIR
>M28_Spy1729 mipB, transaldolase
MEYMLDTLDLEAIKKWHHILPLAGVTSNPSIAKKEGDIDFFERIREVRAI
IGDKASIHVQVIAQDYEGILKDAAEIRRQCGDSVYVKVPVTTEGLAAIKT
LKAEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQ
LAEAINRENADSKILAASFKNVAQVNKSFALGAQAITAGPDVFEAGFAMP
SIQKAVDDFGKDWEAIHHRKSI
>M28_Spy1670 msmK, multiple sugar transport ATP-binding protein
MVELNLNHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGKSTTLRM
IAGLEDISEGELKIGGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAF
GLKLRKYKKDDIDRRVKEAAQILGLTEFLERKPADLSGGQRQRVAMGRAI
VRDAKVFLMDEPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAM
TLADRIVIMSATKNPQGNGTIGKIEQVGSPQELYNLPANKFVAGFIGSPA
MNFFEVEVKDGRIVSEDGLAIAIPEGQAKMLEAAGYKGKKVTFGIRPEDI
SSRQIVHDTYPSATVTAEVLVSELLGSETMLYVKLGQTEFASRVDARDFH
SPGEQVSLTFNVAKGHFFDRDTEQAIR
>M28_Spy1431 nagA, N-acetylglucosamine-6-phosphate deacetylase
MTCYLKADCFYYPTEVKPAGYLGLHDGVFGEWTEIVPADAQIIDYTGYQI
APGLVDTHIHGYAGADVMDNSAQGIHQMSEGLLATGVTSFLPTTLTSTFE
QLEKVSGTIASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPSYMKTPRLE
EFDAWQKAAKGLIKKIALAPEREGVKEFVSAVTKQGVTVALGHSNGTYQE
AKEAVQAGASVWVHAYNGMRGLTHREPGMVGAVYNLPNTYAELICDGHHV
SPIACDILMQQKGHDHVAMITDCMRAGGSPDGDYLLGEFSVVVANGTARL
KESGNLAGSILKLKDGLRNVVAWGIATPAEAIHMATYVPAVSVGIDDVCG
QIKAGHAADFIVLDKDLTLVATYLNGQKAFDA
>M28_Spy1133 nagB, glucosamine-6-phosphate isomerase
MSSNPSSLIFHQKVKDRLDKNWYIPYNKNTKGLYQLEKENDMKIIRVQDQ
IEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQEMVKSPLDFSDLTSI
NLDEYVGLSVESDQSYDYFMRQNLFNAKPFKKNYLPNGLATDIEAEAKRY
DQIIAEHPIDFQVLGIGRNGHIGFNEPGTSFEEETHVVDLQESTIKANSR
FFTSIEDVPKQAISMGIASIMKSKMIVLLAFGQEKADAIKGMVFGPITED
LPASILQKHDHVIVIVDEAAASQLD
>M28_Spy1563 norA, quinolone resistance norA protein
MLMPFDSNTYIIPLKYIIFCFFCKMFMKIERSSFSMEEKLFNKHFVAITV
INFIVYMVYYLFTVIIAFVATRELGAQTSQAGLATGIYILGTLLARLIFG
KQLEVFGRRLVLRGGAIFYLLTTLAYFYMPTISMMYLVRFLNGFGYGVVS
TATNTIVTAYIPARKRGEGINFYGLSTSLAAAIGPFVGTFMLDNLHIDFR
MVIVLCSVLIGCVVVGAFAFPVKNMSLNAEQLAKTKSWTVDSFIEKKALF
ITAIAFLMGIAYASVLGFQKLYTSEIHLTTVGAYFFVVYALIITITRPAM
GRLMDAKGDKWVLYPSYLFLAMGLFLLGSVSSGGSYLLSGALIGFGYGTF
MSCGQAASIQGVDEHRFNTAMSTYMIGLDLGLGAGPYLLGLIKDLALGSG
VASFRHLFWLAAVIPLICTLLYLLKTKTRQVLS
>M28_Spy0095 pepA, glutamyl aminopeptidase
MTDLFSKIKEVTELDGIAGYEHSVRDYLRTKITPLVDRVETDGLGGIFGI
RDSKAEKAPRILVAAHMDEVGFMVSDIKVDGTLRVVGIGGWNPLVVSSQR
FTLYTRTGQVIPLISGSVPPHFLRGANGSASLPNIENIVFDGGFTDKAEA
ESFGITPGDIIVPQSETILTANQKNIISKAWDNRYGVLMITEMLEALKGQ
DLNNTLIAGANVQEEVGLRGAHVSTTKFDPELFFAVDCSPAGDIYGNPGT
IGDGTLLRFYDPGHVMLKDMRDFLLTTAEDAGVNFQYYCGKGGTDAGAAH
LQNGGVPSTTIGVCARYIHSHQTLYAMDDFVEAQAFLQAIIKKLDRSTVD
LIKRY
>M28_Spy0961 pfk, non-allosteric 6-phosphofructokinase
MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGMVDGDIF
PLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVI
GGDGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAI
DKLRDTSSSHGRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEK
VASTIQYDFEHKGKNHHIIVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLG
HILRGGSPTARDRVIASWMGSHAVELLKEGKGGLAVGIHNEELVESPILG
TAEEGALFSLTEEGKIIVNNPHKARLDFAALNRSLSQ
>M28_Spy0183 pgi, glucose-6-phosphate isomerase
MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSDFLGWLD
LPENYDKEEFARILTAAEKIKADSEVLVVIGIGGSYLGAKAAIDFLNHHF
ANLQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTT
EPAIAFRVFKELLVKKYGQEEANKRIYATTDKVKGAVKLEADANNWETFV
VPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAARKDLSSDKISENI
AYQYAAVRNVLYRKGYITEILANYEPSLQYFGEWWKQLAGESEGKDQKGI
YPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDNPRKNVIIPELAEDLDG
LGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEFTLGYTIYF
FELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL
>M28_Spy1591 pgk, phosphoglycerate kinase
MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTIKYIIEQ
GGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVVFPGVTRGSKL
EEAINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVND
AFGTAHRAHASNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAIL
GGSKVSDKIGVIENLLEKADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKL
DVAKDLLEKSNGKLILPVDSKEANAFAGYTEVRDTEGEAVSEGFLGLDIG
PKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAGTIGVMDAIVKQPGVKS
IIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGLAALTEK
>M28_Spy0910 pgmA, phosphoglucomutase
MTYTENFQKWLDFEQLPDYLRQELLSMDEKTKEDAFYTNLEFGTAGMRGY
IGAGTNRINIYVVRQATEGLAKLIETKGEEAKKHGVAIAYDSRHFSPEFA
FESAQVLAQHGIKSYVFEALRPTPELSFAVRHLNAYAGIMVTASHNPAPF
NGYKVYGQDGGQLPPADADALTDFIRAIENPFAVELADLDESKSSGLIQV
IGEDVDMEYLREVKDVNINQDLINNFGKDMKIVYTPLHGTGEMLTRRALA
QAGFESVVVVESQAKADPDFSTVKSPNPESQAAFALAEELGREVDADVLV
ATDPDADRLGVEIRQPDGSYKNLSGNQIGAIIAKYILEAHKTAGTLPENA
ALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEEKHNHTYMF
GFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDEIYKE
YGYFAEKTISVTLSGVDGAAEIKKIMDKFRENGPKQFNNTDIVLLEDFQK
QTATKNDGTISNLTTPPSNVLKYTLADDSWIAVRPSGTEPKIKFYIATIG
DTLDIAQEKIANIETEINTFVG
>M28_Spy0227 plr, glyceraldehyde 3-phosphate dehydrogenase
MIFIRRKSLMVVKVGINGFGRIGRLAFRRIQNIEGVEVTRINDLTDPNML
AHLLKYDTTQGRFDGTVEVKEGGFEVNGNFIKVSAERDPENIDWATDGVE
IVLEATGFFAKKEAAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHDILD
GTETVISGASCTTNCLAPMAKALHDAFGIQKGLMTTIHAYTGDQMILDGP
HRGGDLRRARAGAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTG
SVTELVVTLDKNVSVDEINAAMKAASNDSFGYTEDPIVSSDIVGVSYGSL
FDATQTKVMEVDGSQLVKVVSWYDNEMSYTAQLVRTLEYFAKIAK
>M28_Spy1525 pmi, mannose-6-phosphate isomerase
MSEPLFLKSTMHDRIWGGTKLRDVFAYNIPSDTTGEYWAISAHPNGVSTV
TNGRYQGQPLNTLYAQEPALFGNPKEEVFPLLTKILDANDWLSVQVHPDD
AYGREHEGELGKTECWYIISAEEGSEIVYGHQAKSKEDLRAMIEAGAWDD
LLTRVPVKAGDFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRKDV
NGNLRDLHIEKSIDVLTIGKPENSVPATIVLDNMVETTLVSTPFFTVYKW
VTSQMVDMKQAAPYLLVSVLKGQGKLYVDQKAYELEKGMHFILPNDVKSW
SFDGQLEMIVSHPNQLV
>M28_Spy1113 pstI, phosphoenolpyruvate-protein phosphotransferase
MTEMLKGIAASDGVAVAKAYLLVQPDLSFETVTVADTNAEEARLDVALQA
AQDELSVIRENAVESLGEEAAAVFDAHLMVLADPEMISQVKETIRAKQTN
AETGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPN
PATINEESIVIAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLE
IAAVLGTNDITKRVKDGDVIAVNGITGEVIIDPSEDQVLAFKEAGAAYAK
QKAEWSLLKDAHTETADGKHFELAANIGTPKDVEGVNDNGAEAVGLYRTE
FLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVRTMDIGGDKELPYFDLP
KEMNPFLGFRALRISISETGDAMFRTQMRALLRASVHGQLRIMFPMVALL
KEFRAAKAVFDEEKANLLAEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEG
KWAGMCGEMAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKME
EYANRALTECSTAEEVLELSKEYVSED
>M28_Spy0758 ptsB, PTS system, mannose/fructose family IIB component
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAV
PNGMKLLIRSVEDSIKLFNDPRAKDKRIFVIVNSVKDACAIAKEVPDLEA
VNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVL
PSNTKVHLSQLVN
>M28_Spy0759 ptsC, PTS system, mannose/fructose family IIC component
MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDMKVGILM
GASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPI
GMLAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLII
ASISFIGILVGSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLW
TNKLAVFYLLGFVLTAYLKLPAVAVAALGAVICVISSQRDLELDAITRGA
ISKQTTFDSKESEEEDFFA
>M28_Spy0760 ptsD, PTS system, mannose/fructose family IID component
MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTLLPVINR
FYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASA
ITAVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLL
YNIPAFIIHYYSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGS
MTASNVKFKTILTVAAKGAKEAASIQDYLDQLFIGIVPLMVTLAAFWLLR
KKVNINWIMFGIMFLGIILGLLGIC
>M28_Spy1114 ptsH, phosphocarrier protein HPr
MASKDFHIVAETGIHARPATLLVQTASKFASDITLDYKGKAVNLKSIMGV
MSLGVGQGADVTISAEGADAEDAIAAIEETMTKEGLA
>M28_Spy1668 pulA, pullulanase
MNVILNGGLMKKKVNQGSKRYQYLLKKWGIGFVIAATGTVVLGCTPSILT
HQVAAKTIVGLARDEAQQGDGNAKSGDGLQSSSKEAKPVLDSSLANPASI
AEHHLRMHFKTLPAGESLGSLGLWVWGDVDQPSKDWPNGAITMTKAKKDD
YGYYLDVPLAAKHRQQVSYLINNKAGENLSKDQHISLLTPKMNEVWIDEN
YHAHAYRPLKKGYLRINYHNQSGHYDNLAVWTFKDVKTPTTDWPNGLDLS
HKGPYGAYVDVPLKEGANEIGFLILDKSKTGDAIKVQPKDYLFKELDNHT
QIFVKDTDPKVYNNPYYIDQVSLKGAEQTTPNEIKAIFTTLDGLDEDAVK
QNIKITDKAGKTVAIDELTLDRDKSVMTLKGDFKAQGAVYTVTFGEVSQV
ARQSWQLKDKLYAYDGELGATLAKDGSVDLALWSPSADTVKVVVYDKQDQ
TRVVGQADLTKSDKGVWRAHLTSDSIKGISDYTGYYYLYEITRGQEKVMV
LDPYAKSLAAWNDATATDDIKTAKAAFIDPSKLGPTGLDFAKINNFKKRE
DAIIYEAHVRDFTSDKALEGKLTHPFGTFSAFVEQLDYLKDLGVTHVQLL
PVLSYFYANELDKSRSTAYTSSDNNYNWGYDPQHYFALSGMYSVNPNDPA
LRIAELKNLVNEIHKRGMGVIFDVVYNHTARTYLFEDLEPNYYHFMNADG
TARESFGGGRLGTTHAMSRRILVDSIAYLTREFKVDGFRFDMMGDHDAAA
IEQAFKAAKAINPNTIMIGEGWRTYQGDEGKKEIAADQDWMKATNTVGVF
SDDIRNTLKSGFPNEGTAAFITGGAKNLEGLFKTIKAQPSNFEADAPGDV
VQYIAAHDNLTLHDVIAKSINKDPKVAEEEIHKRIRLGNTMILTAQGTAF
IHSGQEYGRTKQLLNPDYRTKVSDDKVPNKATLIDAVAKYPYFIHDSYDS
SDAVNHFDWAKATDSIAHPISNQTKAYTQGLIALRRSTDAFTKATKAEVD
RDVTLITQAGQDGIQQEDLIMGYQTVASNGDRYAVFVNADNKTRKVVLPQ
AYRYLLGAQVLADAEQAGVTAIAKPKGVQFTKEGLTIDGLTALVLKVSSK
TANPSQQKSQTDNHQTKTPDGSKDLDKSLMTRPKRAKTNQKLPKTGEASS
KGLLAAGVALLLLAISLLMKRQKD
>M28_Spy0960 pyk, pyruvate kinase
MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAELIEAGA
NVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFA
DDAKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTIL
IDDGKLGLKVIDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAE
RDNADIRFGLEQGLNFIAISFVRTAKDVEEVREICCETGNDHVQLFAKIE
NQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVFQKMIITKVNAAGK
AVITATNMLETMTEKPRATRSEVSDVFNAVIDGTDATMLSGESANGKYPV
ESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVKDATHSMDI
KLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
KPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK
>M28_Spy0584 rgpCc, polysaccharide export ABC transporter permease protein
MNFLTKKNRILLREMVKTDFKLRYQGSAIGYLWSILKPLMMFTIMYLVFI
RFLRLGGNVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFS
KHIIVFSAVLGALINFLINLVVVLIFALINGVTISGYAYLSLFLFIELVV
LVLGIALLLSNVFVYYRDLAQVWEVLLQAGMYATPIIYPITFVLDSHPLA
AKLLMLNPVAQMIQDFRYLLIDRANVTIWQMSTNWFYVVIPYLVPFVILF
IGIFVFKKNADRFAEII
>M28_Spy0585 rgpDc, polysaccharide export ATP-binding protein
MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQHVLKDI
NFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVDGKMVSFIEL
GVGFNPELTGRENVYMNGAMLGFTKDEVDDMYNDIVDFAELHHFMNQKLK
NYSSGMQVRLAFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKDS
GKTTILVTHDMGAVKKYCNRAVLIEDGLVKAYGEPFDVANQYSVDNTETA
EDAMNAEKISVSDIAKDLKVSLISNPRITPNDTITFEVSYEVLKDDFTYI
AFSLTDIDRNIWVYNDNSLDYPTQGIGRKCISYQCQLSQLNDIKLKLEVT
VRDKNGQMLLFSTAEQSPQIVIQRNDIDQDDLSALDSASGLYQRNGKWVF
H
>M28_Spy0218 rpe, ribulose-phosphate 3-epimerase
MSTLKIAPSILAADYANFASELARIEETDAEYVHIDIMDGQFVPNISFGA
DVVASMRKHSKLVFDCHLMVVDPERYVEAFAQAGVDIMTIHTESTRHIHG
ALQKIKAAGMKAGVVINPGTPATALEPLLDLVDQVLIMTVNPGFGGQAFI
PECLEKVATVAKWRDEKGLSFDIEVDGGVDNKTIRACYEAGANVFVAGSY
LFKASDLVSQVQTLRTALNV
>M28_Spy0675 rpiA, ribose 5-phosphate isomerase
MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQEGLQVVG
VTTSSVTSKQAEVLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAA
LLMEKIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEK
AGYKPSFRMKGDSRLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEH
GLFNGMVDKVIVASKDGVTVLEVPKAS
>M28_Spy1529 scrA, PTS system, sucrose-specific IIABC component
MDNRQIATEVIEALGGRENVRSVAHCATRLRVMVHDEGKIDKEKAEAIDK
VKGAFFNSGQYQMIFGTGTVNNIYDEVVALGLPTSSTSEQKAEAGKQGNI
FQRAIRTFGDVFVPIIPAIVATGLFMGVRGLVTQPAIMDLFGVHEYGENF
LMYTRILTDTAFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAW
VVASGGDVKPLTFFGFVPVVGYQGTVLPAFFVGLVGAKLEKWLHKKVPEA
LDLLVTPFLTFAIMSTLGLFVIGPVFHSLENLVLAGTQAVLHLPFGIAGL
IVGGIQQLIVVTGIHHIFNFLEAQLIANTGKDPFNAYLTAATAAQAGATL
AVAVKTKSTKLKGLAFPSTLSALLGITEPAIFGVNLRYPKVFVSGLIGGA
LGGWVAGLFGIAGTGFGITVLPGTLLYLNGHLLQYLVTMLVGLGVAFGIA
YTWGYQDRETLPLPAVEVDQTADQPALAEETLYSPLNGTVVDLAAVSDPV
FSSGAMGQGLAIKPEDNTLYSPVDGKVEIVFETGHAYAITSSQGAEVLLH
IGIDTVSMAGDGFESLVAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIV
TNSADYQSVDILAQGHVLIGDQVALIK
>M28_Spy1530 scrB, sucrose-6-phosphate hydrolase
MMDLPQAIRYRPYKEWSSKDYQAITEKMAQSPWHSQFHVEPKTGLLNDPN
GFSYFNGHYHLFYQNWPYGAAHGLKQWVHMTSTDLVHFTETRSRLLPDHA
HDSHGAYSGSAYAIDDKLFLFYTGNVRDANWVRTPLQVGAWMDKQGNISK
IPQVLIEQPDDVTEHFRDPQLFSYQGQFYAIIGAQGLDGKGKIKLYKAVD
NHVDNWRFIADLDFDDSGTEYMIECPNLVFVDDKPVLIFSPQGLAKADLD
YQNIYPNTYKIFESFNPETGQLLGGGALQNLDFGFEAYATQAFSSPDGRV
LAVSWIGLPDIDYPTDRYDYQGALSLVKELRIKDGILYQTPVSALQNLRG
PAELFHNKIDSSNCYELELTIPGQKKLDLLLFADQKGNGLRLKVDTTKGQ
LSIDRSRAGVQYAQDYGTVRSCQIPQGHVTLNVYVDNSILEIFINQGQKV
LTSRVFPTQGQTGIQVVEGQAFGHYYEMRY
>M28_Spy1526 scrK, fructokinase
MRHGCLDKSLCHHKDKKEQEKGENMGKLYGSIEAGGTKFVCAVGDEEFTV
VDKTQFLTTTPEETIARTIAYFKAFEADLAGMAIGSFGPIDIDPSSETYG
HITTTPKSGWANVDLLGQLSAAFKIPFDVTTDVNSSAYGEVLARPGVESL
VYYTIGTGIGAGAIQHGHFIGGLGHTEAGHTYVMPHPDDMAKGFLGVCPF
HKGCLEGMAAGPSIEARTGVRGERLDQEADVWDIQAFYIAQAALQATMLY
RPQVIVFGGGVMTQEHMVLRVHDKFTTLLSGYLPVPDLTDYIVTPAVADN
GSATLGNFALAKLAAQGK
>M28_Spy0122 sloR, PfoR
MDIIIGTSLLILVLAIFSLFNYKAPHGAKAMGALASAACASFLVEAFQDS
FFGKVLGFQFLSEVGGANGSLSGVAAAILVAIAIGVSPGYAVLIGLSVSG
TGIIPGFVAGYVVSFLIKWMEKNIPGGLDLISIIIVGAPLTRFLAQLITP
VINSTLLTIGDILTSSANSNPIIMGMILGGTIVVVATAPLSSMALTAMLG
LTGIPMAIGALSVFGSSFMNGVLFYRLKLGERKDNIAFAIEPLTQADVTS
ANPIPIYVTNFVGGAACGVLIALMKLVNDTPGTATPIAGFAVMFAYNPVA
KVLITALGCIIISLIVGYIGGSVFKNYRLVTKQELQARN
>M28_Spy1418 tkt, transketolase
MATVSTGSLIFIVQKNSPMMSKLVFFWQNREKEFRDFGGFSEKSVYFCDT
IDNRKRLILVVINREVLLMTFDAIDQLAVNTVRTLSMDAIQAANSGHPGL
PMGAAPMAYVLWNHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLHLA
GYDLSVEDLKNFRQWGSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAM
AEAHLAAKFNKPGFDIVNHYTFALNGDGDLMEGVSQEAASMAGHLKLGKL
VLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHILVKDGNDLEEIAAAI
EAAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFAKKAYQW
THQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAVYEAEYPELAAEYQK
AFTNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSAS
NNTMVKAETDFQPGHYEGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTF
FVFSNYLLPAVRMAALQNLPTVYVMTHDSIAVGEDGPTHEPIEQLASVRS
MPNFNVIRPADGNETNAAWKRAIAETDRPTMLVLTRQNLPVLEGTKELAE
DGLNKGAYILSEAKGDLEGILIATGSEVKLAMDTQEALEAEGIHVRVVSM
PSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGLAGKTLTID
TWGASAPGNRIFEEYGFTVANATELYKSL
>M28_Spy0488 tpi, triosephosphate isomerase
MSRKPIIAGNWKMNKNPQEAKAFVEAVASKLPSTDLVDVAVAAPAVDLVT
TIEAAKDSVLKVAAQNCYFENTGAFTGETSPKVLAEMGADYVVIGHSERR
DYFHETDEDINKKAKAIFANGLTPIVCCGESLETYEAGKAVEFVGAQVSA
ALAGLSAEQVASLVLAYEPIWAIGTGKSATQDDAQNMCKAVRDVVAADFG
QEVADKVRVQYGGSVKPENVKDYMACPDVDGALVGGASLEADSFLALLDF
LN