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# Prochlorococcus marinus subsp. pastoris str. CCMP1986, MED4

>PMM0243 possible Thy1 protein homolog
MSKVELISLTPEAEKTMAYIARVSNPSNQANDKFAGLLRYCIKHEHWSVF
EQSCMTLKIETNRGIAAQILRHRSFTFQEFSQRYAETSLLGNEIPIPNLR
RQDQKNRQNSIDDIPDELKIKFSEKISKHFQEANKLYEEMLNEGIAKECA
RFIMPLATPTRIYMTGSCRSWIHYIQLRSKEGTQKEHMEIAEDCKKVFIK
YFPSVSEALNWE
>PMM0986 conserved hypothetical
MNKKKLYLANPYGFSKQTKNLLPEFIKIFQNLNVEVYEPFERTKHLITNK
NNWAYDLAKANFNDLKSCDCIFAIVNGNPPDEGVMVELGISIALNKEIFL
FRDDFRNCSDSDQYPLNLMLFVGLSKESWSKNYFESIEDILNPKKSFLNW
AKRI
>PMM0067 HIT (Histidine triad) family protein
MAETTIFSKIINGEIPCEKLHEDELCLAFNDIASQAPVHFLVIPKKPLVS
LCECLEEDRDLLGHLLLIGKNIAKSKQLKNWRTVINTGEESGQTVFHLHI
HFLAGRKMSWPPG
>PMM0514 putative dihydroorotase
MGKSFFFENINILMGSNATVIKDNLLIIDGKIEAFGNKAKEDALKKNIKI
SKSGNKILAPMLVDSHSFLEDPLTGVDDNLENLKFRAKKSGFGTIAFLPN
SNNWRDNPEKIPFQKNYDFDLNIYFWGSLSLEDQGKKLSPHCELLKSGSI
GLSTSNFFDNSIIFKGLSLDAVKKSPILFSLTKKNSLQKGIINKDIKTLQ
SGFYIIDNNNEIAEVRNILGIKNIFPDKNIVIKNISDSNSLKEIEKHAIP
ISTTISWWSLIADTNNLEFDDLGWKVDPPLGSQENREFLIKGLENDLIQA
IAVNSKALSDEDIFIPINDRPAGISSFELVLPLLWKEFVVKRDWPIPMLW
KYLSFNPSNLLGIMQEKLSIGSKRWLIFDPDTKWINNQINLGYDSPSNFP
KKNKLIKGKVIHVGLDF
>PMM0918 putative cytidine/deoxycytidylate deaminase
MNQKTINRHRKIEHLDYLKWMKFILRRSEEVGKVELPITAVIIDENGRCI
GRGSNKREINNDPLGHAELIALRQASWIKNDWRFNECSIIVNLEPCTMCA
AALVQARMGQVIYGTKDDKRGGFGGTIDLSKHESAHHKMKVVGGVLNQDC
KNNIKLWFKKMRNQK
>PMM0046 Nucleoside diphosphate kinase
MIKERTFLAIKPDGVQRGYVSDIIGRFEKKGFKLVGLKQLIPTKQLAQDH
YGVHRERPFFKDLVEFISSGPVVAMIWEGEGVILSARKLIGATKPLEAEP
GTIRGDLAIDIGRNIIHGSDGEETAKFEINLWFNQDEICDWETSDSEWRA
EN
>PMM0279 conserved hypothetical protein
MKKLYLASKNQGKIEEYKKLLLNVNCQLLLQPESIEVEENGITFRENAIK
KASEVSKKTRNYAIADDSGICIDALDGRPGIYSSRYAENDQKRIERVLHE
LDGEKNRGAFFIANVCVCSPSRDVILESEAKCFGNIILSPRGKGGFGYDP
IFEERSTRLTFAEMNNVIKDSCSHRGRALKKIIPGLLEIFS
>PMM0399 Putative deoxyribose-phosphate aldolase
MFNIDYELNEKIHAIIINPYLSLEELNANCDLIQKYNIRNVSTSLNFLSP
IKDALNNHKVNINTLISYPLADLPLDFIDEFVCYAKDNGASGIEYIPNFL
KLSKNDLNSFASEIESINASELPVTIIINKTKLDKELFEKAIEISLELGI
TNFQFGDGFGAAISKVDIVEILKFIGNQNSIKVVGSIKTLTQVVDLFDSG
IDCIGTSNFNEIFKEIRLI
>PMM0388 putative similar to tRNA-(MS[2]IO[6]A)-hydroxylase
MLVDFKRPSSNIKYLSSLSSESWLEQALSNPIEILIDHAHCERKAAGVAI
QLMFRYPSEPDLAEVLSPIAREELEHFEKILVLLKDLGHSLKALKPPPYG
AELAKCVRKEEPYRMLDSFLIAGLIEARSHERLSLLALNSEHKSFKLLYV
SLLESEARHFGIYWKLAQTKFSKNETNKRLEELSNIESEILSQTFALPRI
HS
>PMM1447 conserved hypothetical protein
MSISPTIFIIPTGIGCEIGGFAGDALPAAKLLASASGCLITHPNVMNGGS
LSEQNKDIFYVEGYSLDRFAKGEIGLKSVKQQKIGIIFDSSIEHEILMRH
LQAADACVATLGIDVDSYVLTKEPLGIVIESELQGISEGLIENPDTLIEA
GERLIEKGITAIAIVAKFPDNTDLIETNSYREGKGVDPIAGVEAVISHLI
SKYLKVPCAHAPALSPIELNENLDPRAASEEIGYTFLPSVLIGLSNAPDL
IELNDNNENITLHPSHIESIVVPSGALGGEGVLACIERGLNVISVKNKNI
LNLGNHNLNYPKLIEVDSYFEAAGLILALRQGINLKSIKRPLNKVQELNF
KK
>PMM0776 putative uracil phosphoribosyltransferase
MAMSLKVIVPPHPLIKHWLSILREKNTPNILYSTGYEQLGKWLTYEALRD
WLPYKKESIKTDHGEAEGVFINNDYPIKVIAIMPEGLSLWYGAKEVIPNS
TLLLGELPTKIEDNIGVMVYSDQIKMKSNPIETLIKLKRLGVESNRILLI
SSICSNKGLNEIAKVFPQQVIYTSCIDEEDENSNLLKPGIGNPLLRLSTI
FSDKN
>PMM0695 Glutamine amidotransferase class-I
MKRLLVLQHLEIEGPGLFYQIAKEREMNIEIIRLDQGDDLPKTNKDDLLL
IMGGPMGVKDIGSTKYPWLKKESDFINSELKKKTRIIGVCLGAQLLANAA
AGDVEILKQGSPPKPLPEIGWSQVFFNQSNNDFKKFCETPFHVLHWHGDR
ILLPKNAELIASSIRCKEQFFKIGDLAYGLQFHVELKKEMTERWINENKL
FITKGLGPKGQSILREEDKQYGEKTILKRKELINKLFNLLSK
>PMM0130 Thymidylate kinase
MRGKFIVIEGIDGCGKTTQIDEISKWIPTSGLLRGKQKLVKTREPGGSLL
GKKIRNLILDNHKDNKPSSLAELLLYSADRAEHISKTISPALENQDWVLS
DRFCDSTLAYQGYGRNINLEIIKNIESIVCQGESPDLTIFLEISAEESVL
RREKFIPDRMESEGIKFLEKVNEGFKLIAKEKNWTTISALQDINTITNEI
KETLLKKFSRVNND
>PMM0548 HAM1 family protein
MNSSSVLTIASGNQKKVSEILEMLDVLSLKVKKQPEHLNVEETGKTYFDN
AFLKAKAASLETKTWALADDSGLEVDYLDGRPGIYSARYAKNNDDKLIKL
IRELSDIPYRSAKFISCMVLCDPEGKLVKDATGICWGEILKEPKYPNGEF
ESIFWVKEANCVYGELSHSQLSKLGSRGKAAKNIAPFLKREFGID
>PMM0779 conserved hypothetical protein
MDQFEVKVFIRLRPSVLDPAGEAIKSASSKLGVAGIKSLRIGKLIEVKIE
SNEEDIKEKIELLCDRLFANTVIEDYEYSINKL
>PMM0379 hypothetical
MLFLISYKFSDANAQEKGAKMLTEWYDKGGPQNRPEGYNVKSWIFLPQHG
NGYSVVNTDSLETIWRQWRPWRELMEITIEPCADLDETVALYR
>PMM0874 possible ATP adenylyltransferase
MRNEKYWVKALDQTHLSITNNGLFPLKTTVVTREYYNKNDFIIRELDTSR
FTKKNNYGPNQNPFNPWDKILEVDKVGTNHQLILNKYPVQKGHILLITNT
WRPQDGWLDINDWIAIQMVNEDTSGLWFFNSSPIAGASQPHRHFQLLRRD
HGEIICPREKWFLDFENNNDQDSKLKKNTVVSKFNFLNNSINIYNLYLEL
SNKIGLGNPIDDEKPRFPYNILITNNWIAIIKRKYDHVHGFSVNGLGFAG
YLLVTEKSNINYLKKYGPEKLLENFV
>PMM0301 5'-methylthioadenosine phosphorylase
MINSHFITMNKQHLLPIKESRLGVIGGSGFYSINKIDCHEEIEVNTPYGK
PSDSIRLFKTGNLEIAFIARHGRTHKLNPTEIPYKANIWALRSIGVRWII
APSAVGSLQEQIRPLDIVIPDQFIDRTHKRPATFFNEGAVAHVTMGDPFC
MNLSGILCNVSEENIPGGRQLHRGGTYLAMEGPAFSTRAESNLYRSWGCS
IIGMTNHTEARLAKEAEIAYSSLSMVTDYDCWHQTHQEVSVEMVLENLRA
NTEVANKIVFEIAKVIDKKRPQSKSHSSLKDGLITQKENIPSFTKEKLKI
FTDSYWG
>PMM1433 Phosphoribosyl transferase
MSKPDKKIIILTEDELRKTFSRLTFEIIEKISNLENLLLVGIPTRGVHLA
EVLRKEMLDKTGVDVKKGIIDPTFYRDDQNRVGTRLIEATDFPTSIEKKD
IVLIDDVIYTGRTIRAAIEALLLWGRPKSIMLLVMIDRGHRELPIQPDFC
GRKVPTSKKEIVYLSLKEVDGEDGVYLDKI
>PMM0989 ATP/GTP-binding site motif A (P-loop)
MQLIVISGPSGSGKTTLSKRILKKIKNGIILNTDNYYRTGILSQLLSRTL
TSYFDRKISFNIGLFKRDLEFIVKNGFSDFYYIYNFKSKSIKKVYQNTKN
IRFLIIEGIFGQEILKTLSKENCLLIKLKANKQTCLNRVIKRDFLERGKS
KDLATRDFIKAWELFHKNKKKCNSRNYFNTIVIRKKSDIDLLLKKIINIV
N
>PMM1642 possible transcription regulator
MPLTVSIEDLRGLFTKPYGADAPTKAKWAEFYNENVTFIDPTQETKGLDS
YVEAQEKLVKRCDDVYLETHAISISGNYGFVEWTMGLKIMGKEFIYPGTT
RLIFSDNGLIQEHRDYFDFCGPTFGPVPILGPFIRWLYARFIS
>PMM1539 adk, Adenylate kinase
MKKHLLFLGPPGAGKGTQAALLSAANSYLHLSTGELLRKEIDLDTDLGKQ
VKDIMNRGELVSDQLVLEIVKKNLDKDNNGWILDGYPRNLSQVNSLNDVL
ININQPLEIVFYLDIPDEVLIKRLLIRGRKDDNEKTIKTRLKIYKETTEP
LIEYYKDLALLENIKADGDLKTISADIKQKMACR
>PMM1122 apt, Phosphoribosyl transferase
MEILNELISTYKDHPKEGIDFKDVLEIVQHPIVFKELILKMASSKIVSNA
EALISIDARGFIFGSAISFQVSKPMIFARKPGKLPGELIKKKYTLEYGEN
SLSIQKKSLNNFYSFAIIDDLLATGGTVNCVSNILKDNGKKITGLLTVVE
LIELEGRSKFDFPVESWLKCK
>PMM0951 carA, pyrA, carbamoyl-phosphate synthase small chain
MNHLFKKNAKLVLSNGITFTGYSFGAMGSTVGEIVFNTGMTGYQEVISDP
SYFGQIITFTYPEIGNTGINFEDSESDNSVRGIIVRNFSNNNSNWRSKLN
FNQWLIEKNIIGLYGIDTRALVKILRSNGSMNGVITSEKNDLDSCLEIIS
NTPNMQGLNLAKDVSTKKNYIFKATTMTDFDVREKIHKNINKFRVVAIDF
GIKKSILNRLASHGCEILVLPSNSSFEDVLSHDPDGIFFSNGPGDPSSVL
DGINLAKLLINYGKIPMFGICLGHQIFGLALGGKTYKLPFGHRGLNHPCG
MNNNNIEITSQNHGFAIDPNSLSTELVEITHLNLNDKTVAGLKLINKPIF
SVQYHPEASPGPHDSDYLFEKFVSLMLERC
>PMM0825 carB, carbamoyl-phosphate synthase, large subunit
MPQRGDLKRILILGSGPIVIGQACEFDYSGTQACKALRKAGYEIVLVNSN
PASIMTDPEIANKTYIEPLTPEIVSQIILKEKPDAILPTMGGQTALNLAV
KLSESDFLTNNNVELIGADLKAINKAEDRKLFKESMENINVNVCPSGIAS
DLFEAREVSKQINSYPLIIRPAFTLGGVGGGIAYNLEEFNDLCKSGLDES
PSNQILIEKSLIGWKEFELEVMRDTADNVVIICSIENLDPMGVHTGDSIT
VAPAQTLTDREYQRLRDLSLKIIREVGVETGGSNIQFAVNPKNGDVIVIE
MNPRVSRSSALASKATGFPIAKIAALLSVGYTLDEIINDITKKTPACFEP
SIDYVVTKVPRFAFEKFKGSSNILNTSMKSVGESMAIGRSFEESFQKALR
SLEIGIFGWECDSIEDFNNDNDLKNNLQNPTAERILIVKKAMESGKTNSY
INEITNIDLWFIEKLRNIFNFQNEFLKGNELTRIDRDLMLNAKQLGFSDQ
QIAKLTNSEFFEVRNYRKKLKVLPLYKTVDTCSAEFSSETPYHYSSYEEA
FLHNNLNINDNEISADNHKHLKKIMILGGGPNRIGQGIEFDYCCCHASYQ
ASSNGYQTIMVNSNPETVSTDYDTSDILYFEPVTLEDVLNIIEAENPYGL
IVQFGGQTPLKLSLPLSNWLESYEGIKCKSKILGTSPHSIDIAEDREEFT
KILEELNIRQPLNGIARNEKEAMLVANNIGFPLVVRPSYVLGGRAMEIVK
DKNDLSRYIKEAVKVSPDHPILLDQYLSNAIEIDVDALCDKTGSVVIAGL
MEHVEPAGIHSGDSACCLPSISLSQETIETVKKWTKLIANRLNVVGLINL
QFAIRNHSNEENQLFILEANPRASRTIPFVSKAIGKPVAKLATQLMQGSS
LKDINFTKELIPKYQAVKEAVLPFKRFPGSDALLGPEMRSTGEVMGLADN
FGLAYAKSELAAGNGVPSEGVAFLSTNDLDKDKLEYIARELIVLGFKLVA
TKGTAKYLFNLGIEVDEVLKVHEGRPNIEDSIRSGLIQLVINTPVGSQAL
HDDAYLRRASLEYNIPTFTTIPGAKAALQAIKSLRLNKIDTLSLQEIHN
>PMM1304 codA, possible cytosine deaminase
MINSGKTEVLIPRCLCEIENVDNLNVDDEGFASVFVAWEKGIISELKPIN
IKNKKPKKILFPRFVETHSHLDKSFTFGEFPNFKSNYHEALSVNLEEHKT
RSKIKVLERAEKSLNLALKNGYRAIRSHVDTYESQDNNIWDELFKIQKKY
SSKLKLQYVALAPLEFWDTPHGEELAKIFSKKKGILGGVLVPPFKNRAKI
KYLLSKTLLLADKYKLEIDLHIDESTIEPGAGIKVLLETIDRLNIKVPIT
CSHLSSILSLNNNEILNLGSKIAEKDIKVIALPLTNFWLLNRKEKSTSLN
RPVAPIKQLQKSLVDVSIGSDNVQDPWYPFGNYDPFYLMSLAMPMLQLNP
WERLTLSSIFLSPSRLLNLTWDGVVKKGCPVNFVLLDAGNWADIFSTNLK
REVLINGELYS
>PMM0244 dcd, dCTP Deaminase
MLKNDLWINQKASKGMINPFQSNLVRHLDPNNKKNAVLSYGCSSYGYDLR
LSSKEFLIFKHVPGTVMNPKKFNPDNLEKTILHEDKDGEFFILPAHSYGL
GVALEKMKVPENITVICIGKSTYARLGIIVNTTPAEAGWEGHLTLEFSNS
SGADCRIYANEGICQLLFFEGDPCSTTYEDRKGKYQNQPEKVTLAKI
>PMM0467 gmk, Guanylate kinase
MKNLKKLIIITGPSGVGKGTVIKELLDRNKDIWLSISATTRNPRVGEKDD
LNYYFIGEERFKDMIDKKEFLEWAQFAGNYYGTPLSTVNEKIEKGFIVLL
EIEVEGAKQIKEKFPESLSIFLLPPSKEELEKRIRNRGTEKEEAIDRRLS
RANYEIASSNQFDFVLTNHDVDETVKEVLKIIKS
>PMM0037 guaA, Glutamine amidotransferase class-I:GMP synthase
MSKKLLKKERDPSILILDFGSQYSELIARRIREADVFSLVVSNFTSVKEI
QDINPKGIILSGGPSSVYEDNAPKCDAKIFDLGIPILGICYGMQLMVKEL
GGEVTPAINKAEYGRAPINIDCESDLLSNVQDKSIMWMSHGDSINNLPEG
FIKISHTENTLHAAISNKQKKLFGVQFHPEVIHSEFGMTVIKNFVYSIAK
CKADWTTETFLEETIPRIKQQVGDKRVLLALSGGVDSSTLAFLLNKAIGK
KLTCMFIDQGFMRKGEPEFLMEFFDKKFHIKVEYINARERFIDKLNGITD
PEEKRKIIGREFIRVFEEESNRLGPFQYLAQGTLYPDVIESAGTNLDPKT
GERIAVKIKSHHNVGGLPKDLQFKLVEPLRKLFKDEVRKVGGALGLPDEI
IKRHPFPGPGLAIRILGDVSHEKLNCLRDADWIVRDEIKKAGLYNDIWQA
FAVLLPVKTVGVMGDKRTYAWPIVLRCVSSEDGMTADWSRIPYETLERIS
NRIVNEVEQVNRVVFDITSKPPGTIEWE
>PMM1062 guaB, putative IMP dehydrogenase
MNIEIGLNKKVRRAYGIDEIALVPGTRTLDYDLTNPSWSIGNVKREIPII
ASAMDSVVDVDTAVELSELGALGVLNMEGIQTRYENPKEILSQISSVGKS
EFVPLMQKIYSEPIKEDLIIKRINEIKEKGGIAALSGTPQAAIKFKEILV
KSKIDLFFLQGTVVSTEHLGMEGKETLNIKSLCKSLKIPVVAGNCVTYEV
ADLLMKAGVAGLMVGIGPGAACTSRGVLGIGIPQATAISDCSSARDDYFE
ETGRYVPIIADGGIITGGDICKCLACGADAVMIGSPIAKSSSAPGNGFHW
GMATPSPILPRGTRIEVGSTGSLERIIKGPALLDDGTHNLIGAIRTSMST
LGAKNIKEMQKVEIVIAPSLLTEGKVYQKAQRLGMGK
>PMM1080 kprS, Ribose-phosphate pyrophosphokinase
MTSFITAVDNEEPTFNLTNSRLRLVSGTSNPKLAEEIASYLGIENVPLVS
KRFADGELYVQIQQSIRGCDVFLIQPTCAPVNDSLMELMIMVDACKRASA
RQITAVIPYFGYARADRKTSGRESITAKLTANLLEKSGVDRVLAMDLHSA
QIQGYFDIPCDHIYGSPVLIDYLESLKLEEVVVVSPDVGGVARARAFAKL
MSDAPLAIIDKRRSAHNIAESLTVIGEVKGKTAILIDDMIDTGGTICSGA
NLLKKEGAKRIFACASHAVFSPPSYERLSSKDLFEQVIVTNSIPVIDNYE
FPQLKVLSVANMLGEAIWRIHEESSVSSMFR
>PMM0457 ppx, putative exopolyphosphatase
MIQKKKLSNLQEKDISVASIDIGTNSTHLLIAEINSDLKSFSIKFTDKST
TRLGERDEEGNLTEESIQRVLKTLKRFQEYCKSNGVNQIVTAATSAVREA
PNGRDFLNRVQSDLDIQIELISGSEEARLIYLGVLSGMVLEDKSYVIIDI
GGGSTELILADQKDAIALTSSRVGAVRLKNDFFLDSEPINRERSNFLRTF
IQGSLEPSIEKIKRRLQRGKTVSMIATSGTAISLGNLILSDLGQPKQKMH
GYKFKKENLEIVLEKLIKMPISEIKKIPSLSERRSEIIIPGALILKTSME
MLNFDQLTISERALREGLVVDWMLRQGIIKNEFNIQSNIRKTTIVHQARK
FGVDKERSEKVTNIAFQIYDQTKNIFHGDTDSKAKDLLWAACNLYDCGKY
VNISSYHKHSWYLIKNCELLGYSQSETNIIASIVRYHRKTLPKKRHESWQ
SLISKEDKTLVLEMSLILRLAASLDQRPENVLSSIKIKLLNNIFAIELIP
LKSNKDLLLEKWSLELCSKVVKELKNLELKVV
>PMM0506 purA,adeK, Adenylosuccinate synthetase
MANVVVIGAQWGDEGKGKITDLLSRSADVVVRYQGGVNAGHTIVVDDKVL
KLHLIPSGILYRETICLIGSGTVVDPKILLKEIDMLIDNGIDISGLKISS
TSHVTMPYHRLLDEAMEADRGSNKIGTTGRGIGPTYADKSQRNGIRIRDL
LNEDRLRDVIEIPLKEKNGLLEKIYGIAPLNKDEIIEEYLDYGQRLSKHV
VDCTRTIHAAAKNKKNILFEGAQGTLLDLDHGTYPYVTSSNPISGGACIG
AGVGPTLIDRVIGVAKAYTTRVGEGPFPTELQGSINDQLCDRGSEFGTTT
GRRRRCGWFDGIIGKYAVYVNGLDCLAVTKLDVLDELDEIQVCIAYELDG
KEIDYFPTNSDDLKKCKPIFKKLKGWQCSTANCRKLSDLPENAMNYLRFL
AELMEVPIAIVSLGANRDQTIVIEDPIHGPKRALLR
>PMM1465 purB, Fumarate lyase:Adenylosuccinate lyase
MIERYTLPEMGRIWTENAKFQSWLKVEIAACEANCTLGKMPEAALKEIRL
NAKFEESRIKEIEKEVKHDVIAFLTNINEYVGDSGRYIHVGMTSSDILDT
GLSLQLKDSCELLLEEIEKLENEVRSLARKHKNTLMIGRSHAIHGEPISF
GFKLAGWLAEILRDKKRLLILKESISIGQISGAMGTYANTNPEIEKITCE
LLGLKPDTASTQVISRDRHAEYVQTIALIGASLDRFATEIRNLQRTDVLE
VEEGFSKGQKGSSAMPHKRNPIRSERVSGLSRILRSYVVTALENVPLWHE
RDISHSSNERIMLPDVSICLHFMLREMKEIINNLKVYPDNMLKNLNIYGG
VIFSQKVLLLLVEKGMSREKAYSLVQKSAHQAWNNENGNFKENIEGDQEI
MTLVSENDLKVCFDPSIHLNNLNVIWDKLSI
>PMM1339 purC, SAICAR synthetase
MNSKLKFIYEGKAKKIFAYEDSDKVIIEFKDDATAFNALKKAKFEGKGEL
NCLISSKIFEFLIKNNIPTHYIGLKNNNSMIAQKIKIIPLEVVLRNTAYG
SLCKQTTIKPGTVLESPLIDFYLKNDTLNDPLLTKDRINLLKIVDEEELD
FISNMTLKINKLLKKFFYNIKLDLVDFKLEFGYNSNGQIVLGDEISPDNC
RLWDLNQKNGMIVSLDKDRFRNDLGGFIEAYSEINKRINNFI
>PMM1340 purD, phosphoribosylglycinamide synthetase
MSINTINSKSSNKLENILIIGNGGRENALAWAIQKNDLIKKIYLLPGNAG
SKKINKSERINLDLKNTKVLTSKLKFLNIDLIVIGPETPLAEGLGEVLRR
NNFDVFGPGPDGAKLESSKSWAKEFMKDANIPTANFWKVKSLKEAKKIIF
TSPNPLVVKADGLASGKGVFIPESKEASINATEEIFKGKFGNAGEIIVLE
EKIEGPEVSVFALCDGKKYVLLPTAQDHKRLNENDKGPNTGGMGAYSPTP
MMTKSLLETITKEIIEPTINSLLRKNIDYKGVLYFGLMITKSGPKVIEYN
CRFGDPECQTIMPLMDKDFVILLQKCAKGNLLGNEKIKMSNKFSGCVIAT
SKGYPHNYKKGFPITYGNIDYEHCQIFDSGTSLNSKGEFITDGGRVLSIV
CQGEDFNKVFEKAYKNLKEISFDGIYYRKDIGHQVRIKKIAERTN
>PMM0167 purE, Phosphoribosylaminoimidazole carboxylase
MGSDSDLKTLKPAIDILNEFGIETEVCILSAHRTPMEMMEYAKKAESENI
KVIIAGAGGAAHLPGMIASLTCIPVIGVPVESKTLKGIDSLLSIVQMPAG
IPVATVAINGAKNAGLLAIQILSLFDEALRLKMKKFRENLHTQVRTKNSK
LSALGADNYLKTD
>PMM0004 purF, Glutamine amidotransferase class-II:Phosphoribosyl transferase
MCGIVGIVSCDDVNQQIYDSLLLLQHRGQDSTGIATMENTVFHIHKAKGQ
VNTAYRTRDMRNLIGKIGLGHVRYATKGSAESVEEAQPFYVNAPYGIVLI
HNGNLTNTRDLEKQLFNVDKRHTNSSSDTEMLLNIFATELQEQIHNQDLE
PDIIFNAVKNLHKRIQGSYASIALISGHGLLAFRDPFGIRPLVIGKRISL
ITQKEEWMVASESLVLENNDYHVVRDVEPGEAIFITNNGEFFSKQCSENP
RLFPCAFEYVYLARPDSVMNGISVYQARLKMGDYLAETIKQSIQCGDVDV
VMPIPDSSRPAAMQVARQLGIEYREGFFKNRYVGRTFIMPGHQKRKQSVR
QKLNAMSTEFKNKNVLIVDDSIVRGTTSKQIVQMAKDAGANKVFFTSAAP
PVRYPHVYGINMPNRDELIAHDRSIIEIAEKLEIDHLVYQSVENLRKSII
NDSPIQELEMSCFTGSYVTGTVNQEYLKWVENEYNS
>PMM0266 purH, AICARFT/IMPCHase bienzyme:Methylglyoxal synthase-like domain
MSPLALVSVSDKKNIIPFCTELVEKFNYKILSSGGTAKHLMEAKIPVIKV
ADFTNSPEILGGRVKTLHPKIHGGILAKRTDEEHKKDIEAYDLELIELVV
VNLYPFKKTVEKGSKWEDAIENIDIGGPSMIRSAAKNHKDVSVLVDPSQY
QEFIEESKKGELKETYKAKLALEAFQHTADYDTAISNWIRKERGLQSSKY
IESYPLIKTLRYGENPHQKAFWYGLNNIGWNSAEQLQGKELSYNNLLDLE
SALSTVLEFGYEEKDELTTETFASVILKHNNPCGASIGNSASQAFLNALK
CDSVSAFGGIVAFNSNVDSETAINLKDIFLECVVAPSFDPEALEILKIKK
NLRILKFSKDQIPNKNQTSTKSIMGGLLVQDTDNIEEKTESWITVTKKFP
STQDYLDLSFAWKICKHIKSNAIVIAKDQQTLGIGAGQMNRVGASKIALQ
AAKENGYGGVLASDGFFPFADTVELANEYGINSIIQPGGSIRDEESIEMC
NLKGISMVFTNKRHFLH
>PMM0683 purK, phosphoribosylaminoimidazole carboxylase
MNQKKNIENIQKNYSIGIIGGGQLALMLAEAAKNRGIKVCVQTKSSNDPA
GSKADYVIEADPLKVKGNKDLIKECEKIIFENEWIKIEKLNSIDSKNIFV
PSLESIQPLVDRISQKILIERLNLPSPRWKSIEEFKSLNDEEIESWNFPL
MIKSYKGGYDGKGNTKINTREDLNSFFVETNSEEWIIEEWVDYKNEFALV
GSRDFDGTIRFFPIVETFQKNNICDWVLSPAEIDYDLKTFAKNIFSSIVN
ELDYVGVMGIEFFYGDKGLLINEIAPRTHNSAHFSIEACSSSQFDQYVCI
SSGIKPPEIKMHSQGSLMINLLGLNKKFPLSIKKRLELLSQIRGSNLHWY
GKSKESVGRKMAHITFLLNEDNQSKRFVKSKEILNKVREIWPSPND
>PMM0003 purL, phosphoribosylformylglycinamidine synthetase II
MIDSSSNNTYDVNESLKVENLTRDDYEEICKRLGRKPNRTELGMFGVMWS
EHCCYRNSKPLLANFPTTGKNVLVGPGENAGVIDVGNDQKLVFKIESHNH
PSAIEPFQGAATGVGGILRDIFTMGARPIAVLNSLRFGNLDKLSNISLLR
GVVSGISHYGNCVGVPTVGGEIDFDDSYSGNPLVNVMALGLLETDEIVCS
GAKEVGSPVLYVGNTTGKDGVGGASFASSELNTNSLDNRPAVQVGDPFIE
KSLIEACLDAFKTGDVLSAQDMGAAGLTCSSAEMAANGSLGISINLDLVP
ARENDMSAYQYLLSESQERMLLVVKEEKLNTLINQFKKWGLFANVIGEVI
SRKEVIISQKNQIVAQIPTSALSDETPINIHNIIKEPPIHLLEKWEWTEE
ELPAISENKILSLKDQQKYSFSEIILKLLSNPSIASKSWVYRQYDSQVQS
NTVFKPGDADAALIRLRRQDEKNKNNEFSGVAASVDCNSRWVLLDPYRGS
IAAVAESARNVSCVGAQPIAITNNLNFSSPETEIGYWQLSSACDGISKAC
IALETPVTGGNVSLYNESKNQNNQVTPINPTPVIGMVGTIKNVDKAISSG
WKNINDQIWIIGSNASESSIAASSYLEYFHDLVTGRPPKIHLQDEKYCQS
FLRDSIQKNYIASSHDVSDGGLAVALSECCILSSKGAYIQLEEKNARQDN
LLFSEGGSRILFSVNKKEEQNFLNFLEIKSKDFGRNVYVKKIGFVSEHNL
DITLQDQTLCNLRVDELTEKFNNSISNCF
>PMM1589 purM,purG, phosphoribosyl formylglycinamidine cyclo-ligase
MDYKTSGVDIKAGREFVSEIKQSVESTYSSNVLEGIGGFGGLFKIPLEGL
KKPVLVSGTDGVGTKLELAQIKNFHFEVGIDLVAMCMNDIITTGAKPLFF
LDYIATGKLEKNQLLEVINGIAHSCRENKCSILGGETAEMPGFYSKNKYD
LAGFCVGIADEEKLINGKKICENDLIIALQSNGMHSNGFSLVRKIIENNN
QIDKQFEKKYNLDFYDELLKPTKIYFKIVNQILSQNIQIKGMSHITGGGI
PENLPRCMSSDFIPYIDKKSWKIPVLFEFLKDVGQIPEKDFWNTFNLGVG
FCLIIDKKYKDKILNICNAFDISSWVLGKVLKKNNSKENNFLPEIII
>PMM0891 purN, phosphoribosylglycinamide formyltransferase
MDKSFNYLISPEISQLREFSPKLKIAILASGEGSNFQELIDLSNSNKFDI
DIKILITNKSEAGCISRAKNSNISYKVIKSSDYENKDYFENEIINTIKKQ
DIELVVMAGWMKIMSSKFVNEFKNKIINIHPSLLPSFKGSNAIKEAITND
AKITGCSVHFVEPEVDSGPLIMQAALAISDKDNLETITQKLHILEHKVLP
LSISQAGYIIRNKFMGND
>PMM0780 purQ (purL, pur4), phosphoribosylformylglycinamidine synthase
MASFTVGIVVFPGSNCDRDVSWALEGCLDIKTKFLWHESSDLNDVDSIVL
PGGFSYGDYLRCGAIARFSPLINSLHDFIKSGRRVLGICNGFQILTESGF
LPGALVANKNLNFICDDVDLNVITSKGGWFQKLNENQNIKLPIAHGEGCY
HCDQDTLKRLVDNDLIALKYKTNPNGSTSDIAGITNEKGNVLGLMPHPER
ACDESIGGIDGLYTLRSLITQ
>PMM1004 purT, GAR transformylase 2
MSSFKFIPKKILLLGSGELGKELVVEAKRLGLEVIAIDKYENAPAMQLAD
NSFVIDMSDKEILKKKIKELNPDFVVPEIEALSIEALKELEDEGINIVPN
ARTVEITMNRDKIRDLASKELNIKTAKFSYVFNVDELEIKSSEIGFPLLI
KPLMSSSGKGQSLVNRKEDLLLAWNDALKNSRGKIVGVILEEFLNFDYEF
TLLTIRKTSGENIFCEPIGHEQYKGDYQCSWQPLDMNQSLINEARKMTTK
ILNNLNGSGIYGVEFFVRGKEVIFSELSPRPHDTGMVTLVSQNINEFELH
LRAFLNLPIPNISLLKPSATRVIISDKESNTPSYSGLNEALELENTKVLI
FGKPTAKKGRRMGVVLSTDDDLNIARENADKSALKIKIVS
>PMM1702 purU, formyltetrahydrofolate deformylase
MEHPSIIFKIVCPDRPGLVSKLTSWISDYGGNIKHSDHHTDQDAGLFLSR
IEWNSIHTTINRKDIYDKFQTIAVDINGKFNINYSDEIPNVAIFVSKQNH
CLIDLLWRVRNGELKMNVPLIISNHPDLESIANDFNSQFVYFDTVNSSKS
DVEDQILKLIDQFDIDFVVLAKYMQILSDSFVQKFSSIINIHHSFLPAFK
GAQPYHRAWKRGVKLIGATAHYVTKDLDEGPIIEQCTVNVSHRDEVDDLI
RKGRDIERVALARAVRLHLNHQVFVYKSKTAVFD
>PMM0233 pyrB, aspartate carbamoyltransferase
MGNWPHKHILTLSNFSIDDYESVIELTERFKSLNNAGTKKIPALQGKLIT
SIFFEASTRTRNSFELAAKRLSADVQSFSPSSSSLSKGETLIDTALTYAA
MGSDILVIRHSSSHVPLEISKKLDASKAKTSVLNAGDGLHSHPSQGLLDL
YTLIKFFSPKLLKPEILNSKKILIVGDVIHSRVARSNLWALTAFGANIIL
CGPPTLIPEEFTDFVSSSPPNQLRDPISSRGSITISSSLEESIKCADAVI
VLRLQKERMIENLLSSIKSYSENYCLTPEKLSLNCKDIPILHPGPINRGI
EISSRVVDEYPNCLINDQVSNGIPTRMALLYLLSKFNN
>PMM0569 pyrC, Dihydroorotase
MKELTISKPDDWHLHLREGIVLKNIIRFTSQYFGRAIVMPNTKNPITSIE
KCISYKNSIFEALSNNSTFEPLMTIYLTDETIKHELVEGFKNKVFFAAKL
YPANATTNSRHGVKKIENLYEIFEVMQELGMPLLIHGEVTDPEVDIFDRE
EVFIDKELSPLIQQFPRLKIVLEHITTSYAVDFVQRNNLGATITPHHLHI
NRNAMFFGGLNSDFYCLPVAKRENNRIALRKAATSGKECFFIGTDSAPHL
RQWKAFCGCAGIFNSPVAIESYLKVFEEENALNQFEKFASLNGPNFYNLP
INNEKIRLVSRSNKIPEFIEVIEQNKVVGQIKPFHGGETLTWRVEGVVK
>PMM0199 pyrD, Dihydroorotate dehydrogenase
MIDQKGIFNNIYKNLVTPILKKDTGIDAEYLTNFSLSLLTFSSNNRDWPL
ISRIIKSLNQEFCVVDKRLHQKICGIDFCNPVGLAAGFDKNGNAANIWKE
FGFGFAEIGTVTKFAQSGNPKPRLFRLAKEQAALNRMGFNNHGAENLVKN
FLKQNVDLKKHRKNNCLGINFGKSKITSLSKATEDYLTSLKLLIPYCDYA
VINVSSPNTEGLRKLQDPILLKELLREVKNLDNCPPLFVKIAPDLSYKDI
EDICQLIIDENIDGIIATNTSLDRLGFEQRKIKQTGLLLSEENGGLSGKP
LQRKANKIIRHIHNIDNNINLIGVGGIDSPESAWERICSGASLVQIYTGW
IYKGPQLVPNILNGILKQINIHQLSNVREAIGSNLEWIE
>PMM0275 pyrE, Orotate phosphoribosyltransferase
MNNFSQKNKLNKENLLKLLIEKSYKKGNFTLASGKKSAHYLNCKPVSLNG
TGLKLISNLFLELMDPSSKAVAGLTLGADPLVSGLIVTAASQGLLIDALI
IRKEIKEYGTKAGLEGPILKEGTEVTVLEDVVTTAGSAIKAINKLRENNL
LVKEVLSIVDRREGGYEALKEQNIQLKSLFSIEDFL
>PMM1328 pyrF, orotidine 5'-phosphate decarboxylase
MKKFNTEEKIILAIDGLDIFQAKVLLERCPNIKWVKVGLELFTREGPSVI
KILKNLNKKIFLDLKFHDIPNTMSAACYEVSKLGVDIISVHASAGSKALT
ASKKASLEGAKIATVNAPCVIGITVLTSLSSEEFQTDLDRKNSIEENVIR
LAKLSFDAGLDGCVCSPLEAKILRSMYKNNFELITPGIRTNIQKKDDQNR
IMTPFEAISNGSSKLVIGRAITKAKDPNKAFLDICESIC
>PMM1689 pyrG, Glutamine amidotransferase class-I:CTP synthase
MSKFVFVTGGVVSSIGKGIVAASLGRLLKSRGYSVSILKLDPYLNVDPGT
MSPFQHGEVFVTEDGAETDLDLGHYERFTDTAMTRLNSVTTGSIYQAVIN
KERRGSYNGGTVQVIPHITREIRERIHRVAANSNADIVITEIGGTVGDIE
SLPFLEAIREFKNDVNKNDVAYIHVTLLPYIKTSGEIKTKPTQHSVKELR
SIGIQPDLLVCRSDKEINEGLKRKLSGFCGVNLNCVIEALDADSIYSVPL
SLKNEGLCKQTLNCLELEDKECDLENWEKIIHNLRNPGNPIKVALVGKYI
ELGDAYLSVVEALRHACIEQKALLDLYWISAEMIEEKSAEEYLNDVDAIV
VPGGFGNRGVNGKIEAIKFAREKNIPFLGLCLGMQCAVIEWARNIAQLPD
ASSSELNPDSENPVIHLLPEQEDIVDLGGTMRLGVYPCRLQKNTTGKELY
NEDVIYERHRHRYEFNNYYKQSFLDSGYKISGTSPDGRLVELIELVDHPY
FLACQYHPEFLSRPGKPHPLFKGLIKASQEKLEQSN
>PMM0522 pyrH,smbA, uridylate kinase
MTYKRVLLKLSGEALMGDKPYGIDPAIVQSIAEDVERVIANKVQLAIVVG
GGNIFRGLKGSADGMDRATADYVGMLATVMNAISLQDGLERVGVETRVQT
AIEMQEIAEPYIRRRAMRHLEKGRVVVFGGGCGNPFFTTDTTAALRAAEI
NAEVVMKATKVDGVYDRDPNKFKEAKKYSSLTYQQVLSDEIAVMDSTAIA
LCKDNNIPIMVFDIFKKGNISRAVAGESIGSLIS