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# Mesoplasma florum L1, L1; ATCC 33453

>Mfl556 uridine monophosphate kinase
MKYKYSTVLLKLSGEALKSENEIYNKEKLEDIAKQIVELAKNGLKLGIVI
GGGNIWRGKLGTDIDMPQINADYMGMLATVMNGLALESTIKRLGYDKVNV
YSSLPIETVTDDYNFKRARLKMNEGYISIFVGGTGFSYFTTDTNSVIRAI
EIGADAVLMAKNGVKGVYDSDPNLNPNAKFYKKLTHREIAENQLRVMDLT
AATLAKDAKLPIEVFDMQGQNNIIKVMEGSLESTIIEE
>Mfl343 IMP dehydrogenase (Inosine-5'-monophosphate dehydrogenase)
MRINMNKDLNGKIINEAITFDDVLLVPNYSEVLPHEVCLKTKLTKNIELN
IPIISAAMDTVTESELAIAIASIGGIGIVHKNLTIEQQANEIKIVKSIKP
TDEFPNACVDANGFLRVGGAVGVNDETLTRVEGLISAGIDVLVVDSAHGH
SKGIIDVVKAIRVKYPNLDIIAGNICTVEGAEALYKAGADCVKVGIGPGS
ICTTRVVAGVGVPQITAINDVYNWSINKDVTLIADGGIKYSGDVVKALAA
GAHSVMLGSMLAGTEEAPGQEVIINNKRYKTYVGMGSLAAMKRGSSDRYF
QKGAKKLVPEGIEAVVPFKGTLEEVIFQLVGGLRSGMGYTGSNTIETLRH
NAKFVKITGASLKESHPHDVEISAEAPNYK
>Mfl372 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase (purine nucleosidase)
MKLIIGAMHEELQDSIAFYKLNKVENEKFTIYKNEEIMFCITGIGLVNAA
AQLSYILSKYDIDSIINIGTSGGCDKELKQGDILIIDKIYNSVADATAFG
YAYGQVPRMPKYYETSNKDIIKTISKAKIKNIASSDIFIHSTEQVKNFIN
KIEDKISVLDMECFAYAQTAYLFEKEFSVIKIISDVIGEKNTNNVQFNDF
IKIAGKEILEILKKIL
>Mfl375 putative xanthosine triphosphatepyrophosphatase
MNKKELWIASNNEGKIKEFKLLLPDYEIKSVKDLPEYVEPEENGETLLEN
AKIKAEALSKYINGWAIGDDTGYFFDALDGFPGVYSRRWAYPVTDFKEIC
KMIMQKTKDSDNKNMSMQTAIVICNYEENQSFEALGITKGLMGEELKVSD
HTFGYDYIFKPEPFNVYCADLTEEDKINCSARAYALNDIKKIIEKEIK
>Mfl144 adenylate kinase
MNIMLLGAPGSGKGTLAEKLIKNQGFNQMSTGDLMRKEINDETPLGIECA
RYMNEGRLVPDEVTMGIVKNFLQDNHNQLIFDGIPRTLNQAKILEENLIE
LNAKIDKVIYIDVPSEILLNRISGRLICPKCKVSYHIISRKPKLEGICDN
DGTELVRRPDDAPEKVKVRLEAYANETAPLVDYYKNKPGFIHIVDNANTT
AEEVYAEVLGAL
>Mfl075 adenylosuccinate lyase
MIKRYSVNKIEKIWDENNKLNVWLDVEKKVTFAWMKLNVISKEEYLLIDK
NAKINIGRMLEIENETRHDVVAFTRAISETLGNEKKWIHLGLTSTDVVDT
AQNKLIQESNEVVLESLINLKNTLKEKALIYKKTLTMGRSHGIYGEPTSL
GLKFLLWFDEIDRQIERFSLARKQIEVAKISGSMGNYANLEFEIEEIVAE
QMGLGIDNISTQVTQRDRHAFLISVFANIASTLEKIATEIRLFQRSEVKE
WHEGFKANQKGSSSMPHKKNPISSENITGLSRYLRSFTNTAFENNVLWHE
RDISHSSNERIIFSDVFNVLVYTLDRLKNTLDDLVIDENKMLEHINSQFN
VFYSQPILNYLLINCDKSREEIYDFIQKCTFETMNNKVDFKQSLINNGIE
KYIDNIEVLNKLFNIDYFIRNVEKIYNRTLNK
>Mfl528 ribonucleoside-diphosphate reductase alpha chain
MEDKKINTLSGTDESDEYVTLNARAKILAAGSDNFKLDVDAAKAYLKHHV
EPRLVKFGSVKERIEYLVSNGYYEEELINKYTIEQIEEITDIAYGFHREF
PSFMGAMKFYNSYGLKTFDGQKYLENFEDRAVMNALFLGNGNFESATKTL
RQLMLGRFQPATPTFLNAGKKQRGEYVSCYLLRVEDNMESICRAVTTSLQ
LSKRGGGVALCLTNLRELGAPIKQIANQATGVIPVMKILEDSFSYANQLG
QRQGAGAVYLNAHHPDVMSFLDTKRENADEKIRIKSLSLGLVIPDITFEL
AQKNEEMALFSPYDVEREYGKAMSDISITQEYQNLVKNPNIKKTYINARK
FFLTVAELHFESGYPYILFDDTVNNNNAHAATGRIVMSNLCSEIAQVSTP
STFNDDLSFKSMGDDICCNLGSLNIAKVMESGAEFAEVIEHSINALDLVS
RTSDLSSAPSIQQGNKKNHAVGLGAMNLHGFLATNFIWYNSIEAVDFTNM
FFYAMAYNAFKASHKLALQYGTFDGFETSQFADGSWFNKYTKCAEDKWTP
ETQRVRELFAQYNVTIPTQKDWIELVELIKKDGIANSHLMAVAPTGSISY
LSSCTPSLQPVVAPIEVRKEGKLGRIYVPAYNINFDNMAYYALGAYEVGP
MPIIDIVAAAQQHVDQAISLTLFMTDQVTTRDLNKAYIHAFKKKCASIYY
VRVRQEVLEDSENYECDACVI
>Mfl530 ribonucleoside-diphosphate reductase beta chain
MAKIKNQYYNESVSPIEYAQQGFKGKMRSVNWNVVNDEKDLEVWNRITQN
FWLPEKIPVSNDLTSWRTLTPEWQELITRTFTGLTLLDTIQATVGDVAQV
PNSLTDHEQVIYTNFAFMVAVHARSYGSIFSTLCSSEQIEEAHEWVINTE
TLQERAKALIPYYVNDDPLKSKVAAALMPGFLLYGGFYLPFYLSARGKLP
NTSDIIRLILRDKVIHNYYSGYKYQKKVAKLSPEKQAEMKEFVFKLLYEL
IDLEKAYLKELYEDFGLADDAIRFSVYNAGKFLQNLGYDSPFTEEETRIE
PEIFTQLSARADENHDFFSGNGSSYIMGVSEETEDDDWEF
>Mfl074 adenylosuccinate synthase
MREINSLVVVGSQWGDEGKGKMTDYFAQKADVVVRFAGGDNAGHVINFNG
QKHKVTIIPSGIFNSEVTSVIGNGCAVNLINLVKELETIKNSGVKLGKLL
ISDRAQLILPYHILIDGAQEESRGARKIGTTKRGIGPTYQDKAARLGIRV
ADIEEEDFKETFKEIFEYQMMFLDRMFNVESIDFEETYANLINAYNVIKD
CVTDTGIFVEQAIKNGKKVLFEGAQGALLDIDHGTYPYVTSSNTSANNAS
TGTGISHKLINNTLGVVKAYSTRVGAGAFPTELLNEVGDGIRERGHEYGS
NTKRPRRVGWLDLVALKHAIRTSGIDYLFITLLDVLSGVEELLICDKYIL
NGEEINYIPATSSKHEKCKANYISMPGWKEDITKVKHFEELPLNAKNYLN
KIAEICEVEISGFSVGPDRLQTVITKEIM
>Mfl143 cytidine deaminase
MTEKQNVFKELLKLKDNSYSPYSNFKVACLIYLNNNEIIKGVNVENAAYP
ATICAERTALSQVYSLGYKKEDIKSLELYTDSESLGSPCGVCRQVISELV
NWTTPISIYNKNGFQLETNINELLPHAFEPAQLIK
>Mfl119 thymidine phosphorylase
MNYSFSEIIEKKKHSIELSAEEIKWLINSYVKNNVTDYQMAAFAMAVYFN
GMTKAETLALTQSYVESGYVYDVSEVTGLKADKHSTGGVGDKTSLVYSPL
VASYGVKVCKLSGRGLGVTGGTIDKLESCKGWTSELSKEKFIKTINEVGM
SITGQSDDIVPADKKMYALRDVTGTVDSIPLIAASIMSKKLVIDSDSLIL
DVKVGAGAFMKNVDIAEKLANEMITIGHGYNRKVSILLTDMQKPLGKAIG
NAIEVKEAWDTLNNNGPEDLKEVVCTAAGLTLTDLGIFDKLEDAITDCYK
KLETGECAHYLEEFVEAQGGNFELIKNYDQNFTTKNKIEVFAEKDGYIIS
QDAETIGLLSMDLGAGRKTKEDLIDFSAGIYLNKKTGDVVKTGDVVLTFY
TNFDINNDWIERAKKSFIISTENEKQQNIIKIIR
>Mfl385 deoxycytidylate deaminase
MKRENFLNWEQFFMTVAKVCAMRSKDPSTQVGAILVNNLNQIISTGYNGF
PRGVNDDEFPWTREGEWIDTKYPYVAHAELNAIVSARTNLTDSDVYVTLF
PCNECTKIIIQAGIKKVYYLEDKYKDSNEVKASKRMLDAAKIEYKQINDF
NVKISID
>Mfl648 CTP synthase (UTP-ammonia ligase)
MAKFVFVTGGVVSGLGKGITASSLGNLLKASGLKVFMQKFDPYLNVDPGT
MSPYQHGEVFVTDDGGETDLDLGHYERFIDEKLTKMSSTSAGKIYLETIN
AERRGDWGGQTIQVVPHITDSIKNKVYQAAKTSGADVIISEIGGTVGDIE
SQPFIEAIRQIRMEQGKENVVFIHVALLLYLNASKEYKTKPIQMSVKELL
SLGIQPDIIVQRTDKHSSKEIKEKISLFCNIPTSNVIDAIDKESIYEVPL
EMYEQNLHGLVLDQLQIRTKKTDMESWIKFCEKIKASKEEFEVTFVGKYI
ELQDAYLSVIESLKIAGYEFKRKLKINWIQADKLNESNYKEVLQNAKGIL
VPGGFGDRGIEGMILASKFARENSIPYLGICLGMQIATISIARDWLNLPE
ANSTEFDHSGAVPIFDFIRGIDVQNLGGTLRLGAFYKTTIKEGTKAEKLY
GSREVFERHRHRYEFNNEYKKALEEKGLVFSGIYEEKKLVEIIELPNHPF
FVGSQYHPEFTSRPNKPNPLFKGFVEAIVNNK
>Mfl529 ribonucleotide reductase
MHDDIKLVSGEEIVKPTGEVHVVYFSSISNNTHRFIQKLSVKNSRIPYEL
EEEINVDSDYVLITPTYSGGGEFTSGAVPKQVIKFLNKENNRNYCRGVIA
SGNTNFGNTFAMAGPILSKKLNVPLLYQFELLGTQNDVEKINEILKEFWG
K
>Mfl635 thymidine, deoxyuridine kinase
MIPNRDTIEQKQLGWVELITGCMFAGKTEEFIKRLRRHAFAKRNVIAFKP
VIDTRYAVNEVASHAGTLLPSIPVNSTAELKEKLEAKILEKKVDVVGIDE
IQFFDEAIVDYIEELADRGIIVIVTGLDKDFRSQPFKNVDRILPLAEMVD
KLTAICQKCGNFANRTQRIIDGKPADWNSPLILVDGNDSYEARCRNCYQI
EKG
>Mfl639 deoxyribose-phosphate aldolase
MKLNNYIDATLLKPDATLIEINKFVDLCIIKNVRCICVHISRIAVVKEII
KNTKISISGTVSFPFGNATTKLKINEIKECLKLGANEIDFVANIGNIKDH
DWEKVNSEFQKIRNSFKDIIIKVIFETCLLTEEEIIKCCQIAVKNKLDFV
KTSTGYSKMGATIEHVKLMKKIVNNECKVKASGGIKTKNFALELVEAGAE
RIGTSSISEVLN
>Mfl121 deoxyribose-phosphate aldolase
MKLNKYIDHTLLKQDATKAEIKQLCDEAIEFDFATVCVNSYWTSYCKELL
KGTNVGITNVVGFPLGACTTATKAFEVSEAIKDGATEIDMVLNIGALKDK
NYELVLEDMKAVKKAAGSHVVKCIMENCLLTKEEIMKACEIAVEAGLEFV
KTSTGFSKSGATFEDVKLMKSVVKDNALVKAAGGVRTFEDAQKMIEAGAD
RLGTSGGVAIIKGEENNASY
>Mfl665 purine-nucleoside phosphorylase
MTPHISAKKEDIAKTVLMPGDPLRAKKIAETYLENVKLVNEVRNMFMYTG
TYKGIQVTIAGSGMGCPSIGIYSYELFNFYNVENIIRIGSAGSYKEEIKV
YDVYNVKEAYGDSNYAKLAANIDDKVIKAGDKLYSLIEKIAKDKKIKTLT
GRAHSADVFYRHDDITEFVKENNLDVVEMESVALFANAIKAKKQAACLLT
ISDNLVTKEVTTAEERQNNFMQMVEIALDAAVESN
>Mfl547 deoxynucleoside kinase
MKIAIFGTVGAGKSSISQELSERLNYEIFPEPIDENPYFEDYYKDIKAYA
FRMQIFMLTARSKQLFAAKDLKNKIFDRTIIEDPIFMNVGHKMGNVNDTD
YKTYCDFFQYVVSENLRYPNDRLKFDLVVYLKVSDETSIRRINERGRAAE
LSIDKNYWKILNESYEEYYQEHKNDFPFLVIDANNDNLNEKVEEVIRNIE
KIKKEF
>Mfl107 uracil phosphoribosyltransferase
MAFTELKHPLIIDKLSRMRKKETSSKDFRENLNEIAQLMVYEIFRDLELE
AIEIETPMTKTVGYTIDKPIVLVPILRAGIGMLDGIQKLIPTARIAHIGL
YRDEETLEIHQYFAKKTESIDESYVIIVDPMLATGGSANKAIDIVKGWGV
KNIKFVCLVAVEPGISNVLEKHPDVEIYAASKDEKLSDKGYIIPGLGDAG
DRIFGTK
>Mfl658 xanthine/uracil permease
MKELKQEEIGLALEPREKPKSYGQWFIFSIQHVFAMFGSTVLVPIIINGL
AKEVVMTSSMALFCSGVGTLIYIALTKAKVPMYLGSSFAYMTAIGMNYQA
YGNSVFVAIMVAGLIYILFGILVYYLGTGFIEKIFPVIVIGPLIMIIGLS
AAPSALANAGITSAKSWSDSAKGYAQWIAALIAVFTFMVTIIVTLKAKGI
AKVIPVMIGILSGFVLSLIIHFSMKNSTLIDTTKITDVSQWEWYPSFKPL
WKQEAKNILPAILAISPLAIIAMAEHIGDHIAMGYITKKDFVKDPGIHRT
LIADGVSIVFDGLVGGPPNTTYGENTAVIGMTKVASVWVTGGAAVIAIIL
SFVAPVNQTISMLPEPVMGGVGMIMFGFISINGVRIMITSKTDFMNMRNV
FISATVLVIGVVLSVLGEGIDIGSFNLPGLGLAAFIGIILNLILPTKLNE
GFMCIEWIKSKFKK
>Mfl419 thymidylate synthase
MKQYLELVNEILKDGEKREDRTNTGTISKFGVQKRYDLREGFPLLTTKKV
FYKAIFHEMLWFIKGDTNIKYLVENNVKIWNEWPYENFKKSSEFNNETLQ
EFVERLKNDNEFCNKWGDLGPVYGKQWRDFGGIDQFAKLINDIKKNPFSR
RHIVSAWNPAEVDNMLLPPCHSFWQVYVSKDGWLDLQLYQRSGDVFLGVP
FNIASYALLMELIAKECNLKARYFVHTIGDAHIYLNHLEQINEQLKRKPL
PLCKIKINSEKSIFDIAFEDIEIEGYESHAKITGEVAV
>Mfl215 adenosine deaminase
MKNIENMPKIELHVHIEGTLEAKTVLAKIEQKQLNFDPMYLEKLSKPPVF
TSLSDFLKDYYKNMAVLENQQDFFDLAWNHLKNAKKQNVIYTEIFFDPQP
HIKRGIHLDDVIDGLYQALEKAEKELDLKAKLIMCFLKDESVDEALNILD
MSKLAIENKKIVGIGFDSNEIENWAAIFKPVVDKARNLGLNVTTHAAENS
FEQDPIEVINILNPDRIDHGLYIHKSLEALKLVKEKEIHLSLCPLPNFYS
KAWLDPKTFPIQVFLDNDISFSINSDDPAYFGPTTLNDNYLLVNQNNKIS
EEKWKNLLLKTLNSTFTNTEEKEYLKEKIENYFK
>Mfl676 thymidylate kinase
MFITIEGMDGSGKTTALQRVKQYLEDLNYKVVMTREPGGLPLSEKIRELI
LNKDGVGMEPWTEALLFIAARKEHLEKVIKPYLKKGYIVISDRFMDSTTA
YQGGARGLGVDYLNELQKNILEGFLPDLTLYFELSFEDAEKRLSARPEEK
NRLDEEGRKFKEAVKLAFEELVVKEPNRITVIDASKSPEEVFEETKKVIL
EKIELWKKEKR
>Mfl342 GMP synthase (glutamine hydrolyzing)
MKNTQILILDFGSQYTQLLARRVREANIYTEVLPFDTSIEKIKEYPLLKG
IILSGGPSSVYLQNAYKIDSEILNLDIAILGVCYGMQLLTQYFQGAVELA
DEQEFGKAIITIDDKKNPLFKNVTTESQVWMSHADHVTELPVDFKQIAHS
NASIAAIAHNTKPIYGIQFHAEVTHSLQGKEMLENFLYDIAKCNKDWNLD
DFIDQQIKEIKETVKDKQVILGLSGGVDSSVAAAIIGKAIGKQLTCIFVD
TGLLRKNETIEVMKAYETNFDINIKLVEASDLFFSELKGIKEPEAKRKII
GKCFIDVFTDAARQHKDADFLAQGTIYPDVIESSSHGASSKTIKSHHNVG
GLPEDLKFRLIEPLRNLFKDEVRQVGFKLGLPEEMINRHPFPGPGLGIRV
IEEVTKDKVEILQEADAIFIKKLREWNLYNTVSQAFVTLLPVKTVGVMGD
NRTYDYVVALRSVNTIDFMTATSTHLPWEFLDEVVNEIINKVDNVNRVVY
DVTSKPPGTIEWE
>Mfl170 GMP reductase
MYAFDYEDIQLIPNMCVVNSRSECNTSVTLGKHTFKMPVVPANMATVINE
ELSIMLAEKNYFYVMHRFDFDAVSFIKKMKEKKLISSISVGVKEQDFKMI
NELTELNLIPDYITIDIAHGHANSVKEMIEHIRTKMGDQTFIIAGNVATP
QAVRDLEHWGADATKVGVGPGKVCITKLKTGFGTGGWQLGAIKWCSKAAT
KPIIADGGLRVNGDIAKSIRFGATMCMIGSLFAAHEESPGKNVTVDNVLF
KEYYGSASEYNKGEKRYVEGKKELIKVRGKLMDTYKEMEEDLQSSISYAG
GKTLKAIKKVDYVILKTSNF
>Mfl076 phosphoribosylpyrophosphate synthetase
MLSKKENVHIFGLTQGVELAQEICDILGVKRKEVKTLKFADGEILIESLD
SVRGKEIFVIQSTSTPVNESIMELLIAIDAFKRGSAEKINVVIPYYGYAR
QDRKAKGRQPITSKLVADLLTKAGADRVMSIDIHSPQSMGFFDVPMDNFY
TAQTLATEIIDTIELNNWDPSNCILVSPDYGGMTRVHKVESYTGGVTNGI
AVIGKRRPEPNKAEVEFVLGDIKDKHCFIIDDMIDTGGTIINAAKALKEQ
GAKDVHIFACHGLFNGPAKERMEAAIKEKIVEEVVVTNTIQIADEKKFNG
LKIISVAPLLAEMIDSSISHESLTEVYNNKKQIIWDRAQCIVNKFKK
>Mfl276 adenine phosphoribosyltransferase
MDLKKHILNVKDFPIDGIDFKDVTPLLNDADAFAYVIDEMAKFVIECGAN
VVVAPEARGFLFASAVAYKSHTRFVLVRKPGKLPREVIDIEYTLEYGTNH
QQMHKGDIKPGDKVVIIDDVLATGGTIEAIVKLVEMQEGKVEGVSFLIDL
PALHDENLLQEYKVQKLVKY
>Mfl198 putative cytidylate kinase
MKRKIVIAVDGTAGSGKTATFNTVAKKIGYEFIDTGLMYRAFTLLCIESE
IDFNNKEEIIESLKKFDFSVKNNKPHLNGKEVEKRIQENDIVKFINYVTP
IPEVRKFMVEAQRAMVKGGGYIEIGRDITTVVLPNADLKIFLDSSVEARA
ERRFKQNERLGIKNNNLNEIKNSIINRDEQDFKNGLRKAEDAWLIDNSNI
PIQDVVNMVIDKIKELEGN
>Mfl463 hypoxanthine-guanine phosphoribosyltransferase
MKLHPLVKNVLFTEEQIKERTIEVAKEIKSFYEQNDKEDQSLLVIGLLKG
CIPFYQTFCMNFDFLIDMDFMVVSSYLGGTKSSGEPKINLDVNMSVKDRN
ILIVEDIVESGLTLEFVQNYLLNKGAKSVKILTMLDKPTERKVDIKPDWT
CFSIAKHFVIGYGLDYQEKLRNLPYVAVCDTDKLADWKW
>Mfl245 putative nucleotidyl hydrolase/transferase
MNDCIFCKIIKQEIPSYKIYENEYVYAFLDINPVSDGHALVIPKVHAENL
STTPDLYLSEVSKAKKVVAQILQEKLKGVKGFNYVSNQEAIAKQVVFHYH
EHILPKFKEDEGFLHDKNVNLKYATLEDVFNEITK
>Mfl466 cytidine deaminase
MNYDKLLEIVKKEVYTREFETDKVTAGAVASVLVTKDNNFYTGVCVVMDC
ALGTCAERSAAFQMIKNNETEIKTILTIGRNGYIYPPCGACLELIKLINP
NNKNTQFYISKNQTLNLNQLMIKNWQDKEKMEKY
>Mfl679 cytosine deaminase
MKNLNTYINKIKVKNKSKDIPVFSCLIKDNKIVFKSKNNSYKIKKITGHA
EINVMNKAFKKIKKGNLSEYTLFTTLEPCLMCYGAIKQAKIKEIIYLTEN
VKLSFRNDVNIDQIKINIRKLDHEELQSKYQKIISDFFQKKR
>Mfl306 uridine kinase
MSKNVTLILIAGGTASGKTTVADRIANEILKGKSVTHISMDNYYKDFGEL
TLEERRKINFDHPNSVDTELLLNDLQALKDYQPIKVPVYDFKTSSRTKET
ITVKPSDVVILDGIFALAIKEIRKLGDIKIFIKTANDLRFIRRLQRDVNE
RGRTLESVVEQYLNEVKPMHDAFIGPSIEYADLIIPYKEGNEVAVDLVAT
KILTLLTE