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# Lactobacillus sakei subsp. sakei 23K, 23K

>LSA0430 Putative nucleotide phosphoesterase
METIHILHTNDLHSHFENWPRMRRFLLAHQAAYRQKGETVLTFDIGDAMD
RSHPLTEATDGQINTTLLNQIGYDGVTIGNNEGIGNSHAQLEHLYDHANF
PVLLANLYEQSTNTLAKFAQPYRIITTDQGTRIAVVGLTAPFFLTYRPNG
WDPVTISEEMPQLLAQIEGQYDVLVLLSHLGLTTDQWLAEHYPEIDVMCG
AHTHHLLKDGLMVNQTLLTAAEKYGHYIGDITLTLDANHRPVDRKARTVL
TADLPEEAADEAEIAGYLAQGHAQLAAQVVADLPEALPIATIGESPMMTA
GLKAIEAATQTEAAVLNTGLFLGGLEPGLVTKDDLQSQLPHPMHLIKVTL
KGYDLWRLVLEMEKNRLFLRKFPIKGMSFRGKIFGDIVYDGITVDMTLRR
VFWHGQEIAPEASYTLTTVDHYLFIPFFPTIEIVGETEIMFPDFLRNAVA
TYLTQKYPV
>LSA0259 Pyrimidine-specific nucleoside symporter
MSILMGIVGLVFIFAIGWLVSSNRKKIRYKQIGILLVTQFVISFLCLHTS
GGVKVLAGISNFFSWLMGQAAGGVDFVFGGVVIKSGASVFFLNVLMPIVF
ISALVGILNYIKVLPFIIKWLGKGINKLSGMGELESYFAVSTAVLGQPEV
FLTIKERIPNLSPQRLYTICASAMSAVSAAMLASYMKMVPGKFVVVAVFL
NIFSALIISCIVNPYEPEVEDQKTIEAHLSTEKEPFFQVLGNYIVDGFQL
ALTVAAMLIGFVSLVTFLNNTFGFFFNVTFTDIIGWVFAPVAFVIGVPAD
DIVKVGSLMATKLITNEFVAMGNLSQIAHSLSPKATAIISTYLVSFANFG
TIGIISGSIKAIDKKQGAVVAKFTMKLLLGATMASMLTGTIVGMYF
>LSA1651 Putative purine phosphoribosyltransferase, PRT family
MKVRRSDRLIDMTRYLLERPHTLIPLTFFSNRYESAKSSISEDLSIVKRT
FFNRGTGILETVPGAAGGVRYMPMIKQVEAEEFIAEMAERLSENDRLLPG
GYVYLSDLLGRPEVLRQVGRLIANQYVGKEVTAVMTVATKGIPIAQSVAM
FLNVPFVIVRRDSKITEGSTVSVNYVSGSSARIEKMELSKRSLPENSKVL
IVDDFMKGGGTVNGMKSLIEEFDSEMVGISVFAESVFEGNHMVEDYTSIL
KVDKVDIENKALSVSAGNYLTKNAEQLS
>LSA0446 Putative dihydroorotate oxidase, catalytic subunit
MISTETTLAGIHFDNCLMNAAGVYCYDADELNQIQKSAAGTFVTKSATVV
PRAGNPEPRYLSTPWGSINSMGLPNKGLPYYLDYVSQQQTLFPEKRYFQS
ITGFNIDEDEALLKQITDSDFNGLVELNLSCPNVPGKPQTGYDFETVEQI
LTRVFEVYEGPLGVKLPPYFDIVHFDQMAAILNQFPLAFINSVNSIGNGL
TIDAATERVSIKPKHGFGGIGGDYIKPTALANVHTFYQRLKPEIQIIGTG
GVKSGQDVFEHLLCGASMVQVGTALHKEGPQIFDRLTAELQTIMQQKGYN
KIADFKGKLKYLD
>LSA0055 Putative thiamine/thiamine precursor:cation symporter
MKVNHNQFLLWFGAAISIAEIITGTLIAPLGLVKGSLAIIIGHLIGAFLL
LLPASFLGGTRHQNAIELTAPIYGKIGFILFAILNVIQLIGWTGIMIANA
AQAMQQLKLTHLSYLMNAIIVAGLIIFWLAIKTQFFFKLNNSIVLLLVVA
CLGLFWQLSQFAGHATHLSANPLSFGAAIELSIAMALSWLPLIADYTKDS
KKPLALSLWSTSGYFLGSLMMFFLGFLTVITTGYTDFNQFLATSRFGFLI
LFIIIFSTITTTFLDAYSAGVNLKNLFPKIRYSENGLGIVVTLIGLGLIA
NQQLFKYELFLTLISAAFTPLYTIVFFNYFYRRLPIAVNFSGWLLGAIAY
YGLQRFDFPLGTTVLLMICLWLILCCIAQVVGHRKINR
>LSA1070 Putative bacterial type II secretion/competence system, DCMP deaminase ComEB-like
MANKRMPWNQYFMLQSVLLSMRSTCPRLFVGALVIRNRRIIAGGYNGSVA
HEDHCIDVGCLMRDGHCLRTIHAEMNALTQCAKFGVQTEGAEIYVTHFPC
LQCTKLIIQAGISKIHYQKDYHNDPYALKLIEKSGIELDQVNLSVDDAHT
LVNFLENEQATE
>LSA1210 Putative cytosine:cation symporter (C-terminal fragment), authentic frameshift
MTATIATAITLNHFDPNNADPSTIAAKLGLGVLALLVIVITSTTANAVNL
MAAGSALTNIFPKLKLTPALWCVTLLATVVTFIPVYVASFLTTFETFLDS
IGMFLGPEIAIFLVDYFWIRRRHYQVDALNTIAGPYWYTKGYYLTALFSW
VIGVISYLILNQFAIVHAYTGATFIAMLITALFYRVAVQLQTKKVI
>LSA1212 Cytosine deaminase, (N-terminal fragment), authentic frameshift
MLIQNVHIENQTALKSIRIENGLITAIESHLEPQQNEKIIDGQQQLALPP
FVDPHVHLDSTLTAGQPEWNESGTLFDGIRIWSERKKALTHQDVKDRALK
ALKMQASHGVQFVRSHVDVTDPELVALKALIEVREEAKDWMTLQLVAFPQ
EGILSFPNGKALMTKSAQLGVDAIGAIPHFEFNREYAVESLKFAFELAQE
YDLLFDAHTDEIDDPNSRSLETVATLALETGMKDKVTASHTTAMGCYNDA
YMYKLMRLLKMADLNFTANPLVNLFLGGVLIPIPNAAVSPESRN
>LSA1168 Putative nucleoside deoxyribosyltransferase
MSTNKKIYLAGPFFSPEQIERLDKVAALLAQNPTVETESIFRPNQHSYSE
AEFGSFEWQTATFGFDIRQIDQADLVVAVLDYQTESGQFEPDSGTMWECG
YAFAHNKPVVLARYKDDLPINLMLSGSATAVFNGDADLTNLATYDFNALQ
TKYVATKIY
>LSA1481 Hypothetical protein
MKIYFANALFSQADFDYNTRVVAALRQAMPTLDIYLPQENAAINDKEAYA
NSEMIAQADTEQLVASDLVIAVLDGPTIDVGVASEIGVAYARNIPIVGLY
TDSRQQGATNSQKVAALQTIAENQFHYLNLYTVGLIKLNGTIVNSVDALI
ETVQKY
>LSA0508 Putative nucleoside deoxyribosyltransferase
MQKQIYLAGGWFTPKQADMVARAHKALAANPTVGYIHSPQEHQYKDVTED
NDPNGLFGGYEWANQTYQNDITAMDLADMAVVLWDMADEDTGTAFEVGYL
NASHTPIVFVCEDDLQENPINLMLAKGISKCVTDINELETLDFQFVAGEP
YPGKII
>LSA1847 Hypothetical integral membrane protein
MKKERFEAFTDAVIAIILTILVLELHLPEDDHSWMAILDVRMKFFAYVLT
FIFIATMWVNHHYLFAQVKQINGQIIWVNILLLFWTSLLPATTAWLGTDI
HSVAASTLYNVNVLLFNITTAYLRRLVIKTNPIHNMHMLLIGELVSFSLN
FITLIVSFFYPPFPFIGLSLNIMIWAVVGLRGRITV
>LSA0931 Hypothetical integral membrane protein
MFKAMLRYRLTAIWKTLLIALAIGAVVTTASELILSKQAFSIGLLGASLA
MTGLIVTQLCLIVLSFTMTRPCFEFGILNGISRKTNYATHLVSLLGSQLV
TFMLFYPATAAIFQSHIEDNTNLFDPYLMFIMIIGAWIVIASGIEISSFI
TLFERKIWWIVITLWVVLDILFEHYVHPVINSILPTWTKLTALNFNNASI
MTAAKVVVMSPYFWLTVFTSFVFPLLVAWVCQYFMQTKKIALKWRRSA
>LSA1211 Putative cytosine:cation symporter (N-terminal fragment), authentic frameshit
MAKQHTIHSVAKSERTMGDWDLFATWIGANANNGTWYIGGIIAATGLIQD
STLLIAIGCLSYVLLALASYMGYQTGVGAMGLTRASFGVKGSVLPSLINV
VQFIGWAAVNTYIAATSVSFILKEIMGWSGNDAATNRLSLVVGIIIMSIL
HLISISLGEKSVRWIERIGIVLVIILVTWESIIVFKMVPFKDLVAWRPAA
KFRLEAGRAIDILAAFNLAWVTAAADFSRFAKRKKAATVYSFLGANIGLF
>LSA0628 Putative diadenosine polyphosphate hydrolase
MDDCIFCKIVRQEIPSTVVYEDDVVKAFLDITQTTPGHTLVIPKQHVANI
FEYDADLAAAVFSRVPKIANAIKASNPAIKGMNICNNNGEVAYQSVFHSH
IHLLPRYTAADGFSMQFADNSADYTPEKLQTIADAIKQQLEA
>LSA0798 Pyrimidine-specific nucleoside symporter
MYLLVNIIGLIVFVGLAFLFSKKKSKIKWRSIGIMMAINLFLAWFLTGFP
IGRNIVMGAANGFNWLVQVAYTGIAFALPSWVAVKQMDFVTSVLLPILMI
IPLFDILTYIGVLPWIIKWLGRGLSKVTGQPKFESFFAVEMMFLGNTEAL
AVSALQLKQMKGERNLTLAMMSMSCVTASIIGAYTQMMPGQFILTAIPIN
IINAIIVTNILNPVEVTPEEDTIATMSGSGSDTSDEQVDVQGKEPFFSFL
GDSILNAGKLVLIITANVIAFVALAALIDKILQLINPWITLEHLLGIIMF
PFAWLMGLDVSHAFEFAQFMGTKLVTNEFVVMGKVTNTIGDFAPHYKAIL
TVFMTSFANFSTVGMIIGAFKGLVDKSKNNLIAKNVGYMLLSGILVSLLS
AATVGLFVW
>LSA0335 Putative cytidine deaminase
MGYTQTEIDQWMQVAIDEANQARIIGEVPIGAVIVKDGQIIGRGHNIREH
AQDATLHAEIIAIQEACMVEKSWRLEDTAIFVTLEPCPMCAGAIINSRIP
NVYFGASDPKAGVTGTLMNLLTDKRFNHQATVVAGVREAECAALLQTFFK
KIRENRRKKKKKTGNFKPNRVE
>LSA0287 Pyrimidine-specific nucleoside symporter
MYLLVNVIGLLVFIGVGFLFSKKKKDIDWRSVLIMLVINLVLAWFLTSFS
VGRDIVLGAANGFNWLVQVAYTGIAFALPSWVNVKQMDFVASVLLPILMI
IPLFDILTYIGVLPWIIKWLGRGLAKITGQPKFESFFAVEMMFLGNTEAL
AVSSLQLKQMKAERTLTLAMMSMSCVTASIIGAYTQMMPGQFILTAIPVN
IINAIIVTNILNPVKVTPEEDTIAKMGGSGSAVGEEEAADGKIEREPFFS
FLGDSILNAGKLVLIITANVIAFVALAALIDKVLQLFNPWITLEHLLGIV
MFPFAWLMGLDVSHAFEFAQYMGTKLVTNEFVVMGKVQNSITTFAPHYQA
VLTVFVTSFANFSTVGMIIGAFKGLVDREKNDMIAKNVGYMLLSGILVSL
LSAATVGLFVW
>LSA0023 Putative ribonucleotide reductase (NrdI-like)
MMTNLSILYISLAGNTRSFVTDLQDYAQQQHTTNPALPTIKLTEISDATP
LKDETAPFYAFVPTYLDGGNGIDNGVKELMTNSLGEYIAYGHNADLCYGV
IGSGNRNFNEQYCLTAKRYAEQFNVPFIADYELRGNSRDVGRIYMLLVAN
AQKHA
>LSA1213 Cytosine deaminase (C-terminal fragment), authentic frameshift
MNVAFGEDDIQDPWYPMGDGNMLDVLHAGLHATQMMGYTEIMNAYRFITH
NGARAMHVTDQYGLEVGKPAHLILMASDNFYNALNQRAAVTLSIHAGRII
SETQPATTQLFI
>LSA0013 Putative nucleobase: cation symporter
MADFQSDSARTIEPAPKLSHIKAAILGLQHLLAMYSGDVLIPLLVGAALH
FNAAQMTYLVSVDIFMCGIATLLQLKRTPLTGIALPVVLGCAVEYVGPLT
AIGTNSQLGIDVMYGSIIGAGVFILLISGVVARLRWLFPPIVTGSLITLI
GFTLIPVAFQNLGGGDITAKSFGSVPNLIAGFSTIVLILIFSIWGRGFIQ
QIAILIGIIGGTLVGAAVGLVSLDPVGQASWFKLPELFYFGTPRFEWTSI
ASMSLAALTTMIESIGVFFALGEIVGRNITSNDLKRGFRAEGLAAILGGL
FNTFPYSTFSQNVGIVQLSGIKTKKPVYYSAFFLIFLGLLPKIGAVATII
PTSVLGGAMVVMFGIVGIQGIKMLHKVDLEDNRNLLVATLSIGMGLGIAI
HPTLLQALPASVQTILGNGLVVGSLTAVILNLLVNYRSLIEAKHQQ
>LSA0086 add, Adenosine deaminase
MTQLATRDFIDGLPKAELHLHLEGTLEPELKLALAQKNGVDIGQSTIEEV
QASYNFNSLASFLAVYYPAMNVLQTEDDFYQLALTYLKKAHQENVRYAEL
FFDPQAHMTRGVAFEAVVNGFYRACVDARAFNVDAHLIMCFLRDLSAESA
RQLLEIAKPYQAKILGIGLDSDEHHNPPLKFLREYGDAVAQGYRITMHAD
IDQVDSIQHIQQALEIIRVERLDHGTNIVENPDLVDWVEQLKIGLTFCPL
SNRLVADDMKDREVLELIDHNVKVSINSDDPAYFGGYINDNYEANTTKND
LTIDQVVQLAKNSFETAWISDFQKQTYLAEIDAYVADYL
>LSA0088 adeC1, Adenine deaminase
MIMSDRLTAFKELIQAGGAKRPADLIIKNGQLVNVMTAEIYPAEVAIYQG
KIVAVDPDVSAYQGTETRVIDAKQQYIVPGLIDGHIHVECSKLSMTSFAE
AVVPHGTTSIISGLDEYISVIGVDGLSEIFKEVDQLPMRVFWGAPFKTPY
TIPASTIADNIDSTVQAQLQKRSDVYGVWETVREAVETLDEDTLKTLLNA
QDNHVPVWGCAPMATGTKLNEYLMSGVRVDHESYDHQELLEKVRKGINVV
IRESSVTHFLAENIRAITETNGQIARHVSFCTDDVNAMDIVNKGHLDHLV
RLAIAAGVAPMTAIQMATINSAEAYRIDDQVGLIAPGRNADILLVSDLEA
FEIKRVLAKGQPVATDGHINQSIERPVRPASLANTIIREAVQASDFEYHV
AADASQVTVQTIASEGPFVRHAKTKTLTVEDGIVQIDPAKDVALISVLER
FGKNGNQSLGFTSGWTLKKGAMASTAAPDDNNIIVMGVNPDDMALAVNTL
IERDGGQVVVADGQILSFLPLPIAGIVSDVTPAELAVQEEGILKASQAIG
SEVVDPMFYMTFLPITAIPDLAITDLGNVDCNELRLFDPILTIQ
>LSA1670 adeC2, Adenine deaminase
MDKSTLKQLIDQAAGRKPADTIIKNAKIVDVYNARIIEGTLAIADSRFLG
IDAAYTADNVINAHGQYVVPGLIDPHIHIESANVSPAVFGSLVTPHGTTT
ILADPHEIVNVAGMRGLEYMVASAKNTALDIKYTMPSCVPAANPTLETSG
AVITADEIKQSYDQGLTYGLAEFMNYPGVVNADDGVLDELLVSLNARKMI
DGHSPALHGQGLNAYAAAGVHNDHECTQVDEMLDRISRGMYVYLRYGTVS
KNMPTLLKGVTPQNARFCCLCGDDLQSVTLRETGHLDESIRVAIQNGIDP
LTAIQMATINTAQCTGLSDRGGIAPGLKADFLLVDDLEHFNVNQTFIDGQ
KIAANGAYLLPTDDSVAGFDDLLETVHLDNFSADQLKLNLTSDKAHVIGL
QSISRTQNLVLPVAHDAEGDFHYKPSEDIVKVAVVERHHLTGNVGVGLLS
GFGLQNGAIATSIGHDSHNLVVVGTNDADMVVAIDALKACQGGGVAVQNG
QVIATLPFVIGGLMSTEPIDSLIAHQKAFNTICHEQLNVTAQFDPIMKLG
AMPLDVIPNLRITDKGLVDVTKFEIIDINA
>LSA1744 adk, Adenylate kinase (ATP-AMP transphosphorylase)
MNLMLMGLPGAGKGTQAEKIVDAYHIPHISTGDMFRAAMADQTDLGVKAK
AFIDKGELVPDDVTNGIVEERLSQADTNVGYLLDGFPRTLDQADALAVIT
DKLNKPLDGVINIDVDPEILADRLSGRFICKTCGATYHKLYHPTQVEGTC
DRCGGHVFFQREDDKPETVKNRLKVNIEMNTPLLDFYEKRNLLYTVDGNQ
EIDDVFAAVKKVLDTIKD
>LSA1276 apt, Adenine phosphoribosyltransferase (APRT)
MSINFKDYVASVPDFPEAGVTFRDISPLMSDGEAYAAATDKIVEYAKNKG
VEMIVGPEARGFIVGCPVAYKLGVGFAPARKKGKLPRETVSASYGLEYGK
STLYMHKDAVKPGQKVLVTDDLLATGGTIAATIKMVEELGGIVVGTAFFI
ELKDLNGREKIKDYDIFKLMEY
>LSA1018 cmk, Cytidylate kinase
MQIAIDGPASSGKSTVAKIVATKLGFVYVDTGAMYRSATVLAQQLGLDYG
DEAGLMAELTKADIQFQPDEAGQKVFLNGLDITLAIRTPEITNNVSQVSA
LPAVRTEMVDRQRQIAEQGQVVMDGRDIGTTVLPDAKVKIFMVASAKERA
KRRYAENTAKGIMTPLATLQAEIELRDQKDSTRAVSPLRKADDAIEIDTT
KLLIDEVVAEILTIAKQNM
>LSA0795 deoC, 2 Deoxyribose-5 phosphate aldolase
MNLAKYIDHTLLKPEATMTQVDQIIAEAKTYQFASVCLNPYWVKRASEAL
QDSDVKVVTVIGFPLGATTTATKVFEAQAAIENGADELDMVINVGELKAG
HDEQVLSDIQAVVKAGHAAQKHVKVIIETCLLSDVEKRRACELSEKAGAD
FVKTSTGFSTGGATVADVTLMRSVVGDRLGVKASGGIHSKEDAEAMIAAG
ANRLGASAGVKIMNSK
>LSA0797 deoD, Purine-nucleoside phosphorylase
MSTHIEAQQGDIAETVLLPGDPLRAKYIAETFLTDVHRYNTIRNAFGYTG
YYKGQAISVQASGMGIPSISIYANELIQFYGVKRLIRVGTCGGLGTDVHV
RDVMIAQSASTDSAIIQNTFGAGLYYAPTADFKLLMKAYQAAQQAQIAVK
VGNILSEDRFYNDEIDRQKLIQYGVLGSEMEAAALYMLAAKFNVQALAVL
TISNHIITGEETSAEEREKSFNEMITVALEAGIA
>LSA1805 dgk, Deoxyguanosine kinase
MTLLVLAGTIGAGKTSLTKYLSDHLGTEAFYESVDDNEVLPLFYKDPTKY
AFLLQIYFLNKRFDSIKQAYTDDNNILDRSIFEDSLLFHLNADLGRATAT
EVRVYDELLANMMQELPFAAHKKRPDLLIHVRVSFETMLSRIQKRGRSYE
QLEADPTLYDYYKELNSRYDAWYDTYDESPKMQIDGDVLDFVENEADRKK
VIDMIDQRVKELNEQQSKAI
>LSA1684 dut, Deoxyuridine 5'-triphosphatase
MKKRGFEIVTKYQSANLSLPVRSTAHSAGYDFACAEDFVLPSIWHYNFVR
LFRMIRNGKPLVDDDFERASKTLKPFLVPTGIKAYMQDDEYLMIANRSSN
PLKKGLVIPNGVGIIDSDYYGNDANEGEIFIQMLNFSPRDVILRKGERIG
QGIFMPYLVADDEVAVTTKRTGGFGSSGR
>LSA0947 fhs, Formate-tetrahydrofolate ligase (Formyltetrahydrofolate synthetase)
MSDIQIAQANEATEMKSITAIAEQIGLQATDIEQYGPYKAKLNFQAINRL
KEKEDGKLVLVTSINPTPAGEGKSTVTVGLGDALRQLDQSAVIALREPSL
GPVMGMKGGATGGGYAQVVPMADINLHFTGDMHALTATVNTLAALIDNHL
QQGNVLNIDPRRIIWKRALDINDRALRQVVIGLGGPVQGMPRQDGFDITV
ASELMAILCLATDITDLKNRISKIVIGYNYDREPVTVGDLEVTGAIAMLL
KDALKPNMVQTLEHTPALVHGGPFANIAHGCNSILATQTALKLGDIAITE
AGFGADLGAEKFLDIKVPQLGKTPDTIVIVATIRALKYNGGVALADLTTE
NLDALKAGFSNLAKHIANMQRYGVPVVVSVNEFTSDTAAEVQLLQDLCQA
MKVTAVPTSVWANGGQGGIELAKAVLAALQQPKAFKPLYDPQADIKSKLT
TVVTEIYGGRDVVFEGKAINQLKQIEKNGWAHLPVCIAKTQYSLSDDPKA
LGAPSDFTIHVRELIPKLGAGFIVAMTGAVLTMPGLPKKPAALNMDVTAD
GQISGLF
>LSA0107 gmk1, Guanylate kinase
MVEKQLLVITGATGSGKTTVSHWLTEMYQIPQVVTHTTRPKRHNEVDGVD
YYFETESSLAQKHLIESVTYSGYHYGSSHEALELAWAKSPLISLVVDTKG
AQTYLETFGKQVTVLFLTVSEATALISRLEKRNDSPEAIQKRLASAEFKR
DLMVSGPLHDQAQIIVNDDWQETQKTLTTIIEQLRQ
>LSA0685 gmk2, Guanylate kinase
MSNRGMLIVLSGPSGVGKGTVRQAMLEDEFRDFHYSVSMTTRKPRPGEQD
GVDYYFVSKEEFEQEIANDGMLEYAQYVDNYYGTPMKYVNQTLESGRDVL
LEIEVQGAMQVREKCPDGVFIFLTPPDLLELRNRIQKRGTDDQATIDKRM
QKAADEIRMMENYDYAVVNDEIPNAVQRIEKIIESEHLRVPRVIDQYKKM
IGE
>LSA0139 guaA, Guanosine monophosphate synthase (Glutamine amidotransferase)
MAQKDMQDFDKIIVLDYGSQYNQLITRRIREFGIFSELLPNTTTAAEIKK
IAPKGIIFSGGPMSVYDGGAFSVDPEIFELGIPILGICYGMQLISFKNGG
NVEASTEREYGKAEITVTDKDSDLFKGLPEKQTVWMSHGDKVTAIPEGYV
TVAESDNTPFTAIENRDKHIYGIQFHTEVQNTEFGNDILKNFAFGVCGAQ
DNWTMNDFIDMQIEKIREQVGDKKVLLGLSGGVDSSVVGVLLHRAIGDQL
VSIFVDHGLLRKGEVEQVMESLGGKFGLNIIQVDAKERFMSKLAGVSDPE
KKRKIIGNEFIQVFDEEATKLNGIDFLAQGTLYTDIIESGTSTATTIKSH
HNVGGLPEDMQFSLIEPLNTLFKDEVRDLGEKLGMPYELVWRQPFPGPGL
GIRVLGEVTEDKLKIVRDSDLILREEFALAGLDKTVWQYFTVLPGIRSVG
VMGDGRTYDYTVGIRAVNSIDGMTADFSRIPWDILQKVSVRIVNEVDHVN
RIVYDITSKPPSTVEWE
>LSA0476 guaC, Guanosine 5'-monophosphate reductase (GMP reductase)
MDVFDYEDVQLIPNKCIVKSRSEIDTTVRFGSETFKIPVVPANMQTIIDE
PLAIWLAENHYFYVMHRFQPEKRPAFIKMMHERNLFASISVGVKDDEFDF
INQLAQDNLIPEYITIDIAHGHSQVVIDMIQHIKKVLPKSFVIAGNVGTP
EAVRDLERAGADATKVGIGPGKVCITKIKTGFGTGGWQLGALRWCAKAAT
KPIIADGGIRTNGDIAKSIRFGANMVMIGSLFAGHTESPGELVEEDGQQF
KEYFGSASEFQKGTHQNVEGKRILVPYKGSISDTLTEMRQDLQSSISYAG
GKRLSALRKVDYVLVRHSIFNGDML
>LSA1598 hpt, Hypoxanthine phosphoribosyltranferase
MLEQDIERILYTREDIQRVNEKLGKQITADYQGKNPLMIGILKGAIVFMT
DLIREIDLHVEIDFMDVSSYGDGTISSGEVKIIKDLDTSVQGRDIIIVED
IVDTGRTLNYLMAILKTRQANSIKVCTLMDKPSRRVVPVHSDYVGMEVPN
EFVVGYGLDYAERYRNMGTIGVLKPEIYSGK
>LSA0252 iunH1, Inosine-uridine preferring nucleoside hydrolase
MTKKIILDCDPGHDDAVAMMIAHGNPEIDLLAVTTVAANQTLTKVTRNAL
AVATMIGMHDVPIAAGCSRPLIEEIKVAADIHGESGLDGVVLPKPTVELE
KIHAVDLIIDLIMSHPAKTITLVPTGALTNIAMAARKEPKIIDRVKEVVL
MGGGYHEANASAVAEFNIKFDPEAAKIVFNAGWQVTMVGLDLTHQALATP
DIVSEIKAIHTETSAFVVDLLAFFRDMYKKGQNFDAPPVHDPCAVAYVID
PTVMTTKKVPVDIELNGTLTRGMTVADFSYPIPEDCQTSVAVKLDHAKFW
GLVEDALRTIG
>LSA0533 iunH2, Inosine-uridine preferring nucleoside hydrolase
MTHKMILDLDTGIDDALAIAYALGSPEVELIGITSEYGNVLTERSVVNSQ
QILHLLGHPEIPVYLGAGHSTMTNDFSVLPISAEIHGQDGVGEIHLTQPH
PDAASESAVDFILAACQQYGADLSIVATGPMTNLALAIQKDLPTLQKVGQ
IVIMGGALTVCGNVSPYAEANISQDPEAADLLFKSGLPVTMVGLDVTLRT
LFTKKDTQEWRALATDAAKAYADMVDYYIKAYEVTSPHLHGCALHDPLAV
AVAINPSLVTTFPLNLKTEVEGPSRGRTIGDNARLDDPKTRTAVCVQVDT
PRFLNAFKTRIGQLLKAVK
>LSA0830 iunH3, Inosine-uridine preferring nucleoside hydrolase
MQTRKIIIDCDPGIDDTLALNLAIQSPEVEVVALTIVCGNVPVEIGVDNA
FKCLERLGRLDIPVYAGAAQPLKKTFVSAQDTHGMDGLGDSHIPRQTTTK
AAEQSAADFLATTFKAPCDISIIALGPLTNIATALTLNPQLGANCARFVS
MGGTYKSHGNCSPVAEFNYWSDPEAALAVYEHLNQKIEMIGLDITREIVF
TPTLLAYCQRINPEVGDYLAAITQFYFDFHWQYEHIIGCVINDPLAVAYF
IDPTLCQGFESYTTVETTGISIGQTLVDRFDFWHRPINSLILTEVDTNRF
FEQFLTVVLNAQASIIKTDLKKLR
>LSA1459 nrdD, Anaerobic ribonucleoside-triphosphate reductase
MLEIREEQDPKMDLEIKVLKRDGRILPFSADKIEQAVIKAAKNVKDELEP
LDYQILNSVATDVVSEVGARFDKDVKIYEIQNIVEHKLLEHHQYDIAQEY
INYRTQRDFARNKATDINFTIQKLLAKDQTVVNENANKDSQVFNTQRDLT
AGTVAKAMGLKMLPPKVANAHLKGEIHWHDLDYQPYSPMTNCCLIDFKEM
LNHGFKIGNAEVEAPHSIQTATAQMSQIIANVASSQYGGCSADRVDELLA
PFAQKNYDKHLTDAKNWIDGEAKQTAYAQTKTEKDIYDAMQALEYEINTL
YSSQGQTPFTTLGFGLGTSWMERAIQKAILEIRIEGLGKEKRTAIFPKLV
FAVKRGLNLAPTDPNYDIKQLAVECATKRMYPDVLMYDKLVELTGSFKAP
MGCRSFLQGWKNEQGQEVNSGRMNLGVVTVNLPRIALEAAGDQAKFWEIL
EQRLKVCKEALVFKVERAKEAKPENAPILYRYGAFGKRLKKTDSVDEVFK
NSRATVSLGYIGLYEVGAAFFGPDWEKDATAKQFTLDVVKDLYNHCVDWE
KEYGYHFSVYSTPAESLTNTFCQKDTQKFGIVENITDKEYYTNSFHYDVR
KAPTPFEKLDFEKDYPKYCAGGFIHYCEYPNLRQNPKALEAVWDYAYDRV
GYLGTNTPIDQCFKCGFKGDFKPTERGFQCPQCGNTDPATCDVVKRTCGY
LGNPQQRPMVHGRHKEISSRVKHMHITIGNDNNNVARQ
>LSA0941 nrdE, Ribonucleoside-diphosphate reductase, alpha chain
MSLKEIKTENVTYYELNNQINIPVNGQIPLQKDQEALEAFLEQNVQPNMV
TFKSLQDRLNYMVAENYYEADFLKAYSIDFMERLNQYLIDQDFHFKSFMA
AYKFYAQYALKTNDNGFYLEDFKDRVFTNALYFADGDEALAMSVADEMIH
QRYQPATPTFLNAGRSRRGELVSCFLLQTTDDMNSIGRTINSALQLSRIG
GGVGISLSNLRGAGDPIKGIDGAASGVLPVMKLLEDSFSYSNQLGQRQGA
GVVYLNVFHPDVVAFLGAKKENADEKYRLKTLSLGLTVPDKYYELVKEDA
DMYLFSPYSVEREYGQPFSYIDITAEYDNLVANEAIKKTKIKARDLENEI
SKLQQESGYPYIVNIDTANKANPIDGKIIMSNLCSEVLQVQTPSQINNRQ
EYDVLGTDISCNLGSTNIPNMMTSPDFGHSIETMVRSLTYVTDHSDIDVV
PSVAHGNQLAHTIGLGGMGLHTYFAKNQMMYGSEESIDFTSNYFMLLNYW
TLVASNKIAKERGITFDNFENSKYADGSYFDQYLNTEWAPKTAKVKGLFD
GVFIPTQADWAALKEAIMQDGLYHQNRLAVAPNGSISYINDTSASLQPIV
NRVEDRQEKKIGTIYYPAPGLSNETMPYYESAYDIDMRKVIDIYAAAQKH
VDQGMSMTLFMRSTIPAGLYDWKDGRTDKMTTRDLNILRNYAHHKSIKSI
YYIRTYTDDENEVGANACESCVI
>LSA0940 nrdF, Ribonucleoside-diphosphate reductase, beta chain
MTENYHAINWNQVEDQIDKATWEKLTEQFWLDTRIPLSNDLDDWRSLPDN
EKWIVGHVFGGLTLLDTLQSQDGMASLKANIRTPHEEAVLNNIQFMESVH
AKSYSSIFSTLNTPNEIDEIFDWTNTNEYLQYKANKINSIYQNGSPLQQK
IASVFLETFLFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGY
KFQLGFNELAKAEQEELQNWMYDLLYDLYANEEKYTHEVYDGTGWTEEVL
TYLRYNANKALMNLGQGALFPDTAEDVNPVVLNGMSTSTANHDFFSQVGN
GYRLGNVEAMNDSDYDFD
>LSA0801 pdp, Pyrimidine-nucleoside phosphorylase
MRMVDIIDHKRQGGALTAEEIQFFIDGYTDGTIPDYQASALLMAIYFNDM
TDDERALLTMTMMRSGDQLDLSMIDGIKVDKHSTGGVGDKTSIPLAPMIA
ALGIPIPMISGRGLGHTGGTLDKLEAIPNFNISLTEEAFKKQVAEIKLAI
IGATGNIAPADKKIYALRDVTDTVDSIPLIAGSIMSKKIASGTDALVLDV
KTGSGAFMKTEEDAKELAQALVNIGRSVGMQCMAVISDMNQPLGNAIGNA
LEIEESIAILKGEGPADITELILTLGSQMVVLAGKASTLDEARQLLQGVI
DDGRALEAFRQMIIYQGGDPAVIENPKLMPQAQYQIELPAKENGYVTEMT
ANEMGIASMLLGGGRQAKTDEIDYAVGLVLHKKIGDPVQKGESLLTIYSN
REDIEAIKDLLYDNIKIGPKAQKVTLIHALIQ
>LSA0776 pfs, Methylthioadenosine nucleosidase (nucleoside phosphorylase)
MKISVVCAMEEEIRTLLTKLEDVQEHTVAGNTFYKGQLYGHEVTLVESGI
GKVQAGMTTAILLAEEKPDVVINTGSAGGIGEGLHIGDVVISSQVAYHDA
EATAFGYLPGQLPQQPQRFEGDANTVKQIEAAAKAVDLQPRVGLIVTGDQ
FIASQDKIKAIKEIYPEALSCEMEGAAIGQVATQFGIPFVVIRAMSDVGD
EDAGVTFDEFIVEAGQKSAAMLLNFLKNIK
>LSA1646 prs, Ribose-phosphate diphosphokinase (Phosphoribosyl pyrophosphate synthetase)
MSEQYFDPKLKIFALNSNKPLAEKIAAEVGVPLGKSSVKRFSDGEIQINI
EESIRGDEIFLIQSTSAPVNDNLMEILIMIDALRRASAKTINVVLPYYGY
ARQDRKARSREPITAKLVANMLTMAGADRILALDLHAVQIQGFFDIPVDH
LMGAPLLADYFLSNDLAENAVVVSPDHGGVTRARKLADFLKTPIAIIDKR
RPRPNVSEVMNIIGNVNGKRAIIIDDMIDTAGTITLAAQALKDAGATEVF
ACCTHPVLSGPAIQRIEDSVIKQMIVTDSIDLPKEKLIDKMVQVSVGPLI
GDAIKRIHENKPVSPLFENRFKR
>LSA0063 purA, Adenylosuccinate synthetase (IMP-aspartate ligase)
MTSAVVVGTQWGDEGKGKITDFLGQNADAIARYQGGDNAGHTIKLGEDTY
HLQLIPSGIFNSDKVSVIGNGVVVNPKSLVGELRGLADKNVDTSQLKLSD
RAHVILPYHIKLDSLQEAAKGDQKIGTTNRGIGPAYMDKAARSGIRVADL
LDKDLFATKLKQNLAEKNALFTKIYEVEALDFDSIFEEYYQYGQELKQYV
CDTSVVLNDVLDQKGNVLFEGAQGILLDIDQGTYPFVTSSNPAGGVSTGS
GVGASRIDEVVGVAKAYTSRVGDGPFPTELFDETGDFIRQAGHEYGTVTG
RPRRIGWFDTVVLRHSKRVAGLTQLCLNCVDVLTGLKTLKICVAYELDGE
RIDRYPASLSELARCTPIYEELPGWDEDITGVKTLEELPVNARRYVERLQ
ELVDLPLATFAVGPDRDQTNILKAIW
>LSA0654 purB1, Adenylosuccinate lyase
MIERYTNPEMGAIWTDHNKYEAWLAVEILADETWSKLGHIPAEDVAKIKA
NAQFSIPRILEIEQETRHDVVAFTRAVSESLGAERKWVHYGLTSTDVVDT
AYGYLLKQANAILRADINALIEVIGKQAKRYQDTVMMGRTHGVHAEPTTF
GLKLALWYSELKRHKERFETAAEGVEAGKISGAVGTFANIPPFVESYVCD
QLGIRAQEISTQVLPRDLHAAYVAEMALLATSIEKFATEIRGLQKSETRE
VEEYFAKGQKGSSAMPHKRNPIGSENITGLTRVIRGHMVTAYEDVALWHE
RDISHSSAERIILPDTTILLDYILKRFTKIMTNLTVFPENMKRNMGRTFG
LIYSQRVLLKLIDHGLSREAAYDLIQPKTARSWDEQIDFRPLLEADEQVM
SILTPADLDDAFDYHYHIRHVAEIFERVGLG
>LSA1555 purB2, Adenylosuccinate lyase
MLERYTRPEMGAIWTTENRYQAWLEVEILAVEAWAKLGDIPAEDAAKVRA
NASFDVEEINRLEAITHHDVVAFTRAVSESLGAEKKWVHYGLTSTDVVDT
AQGYILKQANDLIRADIERFMAVLKQKAYEYQNTVMIGRTHGVHAEPTTF
GLKLATWYAEMKRNQERFERAAAGVEAGKISGAVGTFANISPEIEAYVTE
NLGIRAQDISTQVLPRDLHADYINTMAVVATSIEHFATEIRHLQRTEVRE
VEEFFAKGQKGSSAMPHKRNPISSENVSGLARVIRGHVITGMEDVSLWHE
RDISHSSAERIILPDTTILLDYILNRFTRIIEKLTVFPEKMKADMNLTHG
LIYSQRVLLKLVDSGLSREAAYDLVQPKTALAWDEQKDFRQLLEADPKVM
VQLTPAEMDDAFDYHWHLSQVQTIFDRVFK
>LSA0655 purC, Phospho ribosylaminoimidazole-succinocarboxamide synthase
MSETLLYSGKAKDLFSTDDPEVLKMIYKDQATALNGKRKEQITGKGEVNY
EISKLIFAYLSQQGIETHLIKNVSETEQLVKKVTIIPLEVVLRNVVAGSF
ARKFGQPLGQRLEQPIIEYYYKNDALDDPAINISQATALKLVTPTEVATI
EAMTKQINTLLIKLFNEIGIDLIDFKLEFGRYQGRLILADEFSPDNCRLW
DQKTHSSLDKDVFRQNKGDLVTVYETVLQRLTKMIGGFANV
>LSA0663 purD, Phosphoribosylamine--glycine ligase (Phosphoribosylglycinamide synthetase)
MDILVIGSGAREHTLARELLKSEQVEQVYCLPGNPGMQLDQIKTAAIDVN
DFEQLIAFAKKQAVAYTIVGPEQPLVAGVVDAFQAAGLAIFGPTKQAAAL
EGSKTFAKEMMARAQVPTAQYQTVTNESEALTALQGRSLPIVIKADGLAA
GKGVVIAETLADGLAAVRRFFKQGRRQILIEDYLIGEEFSLMALVADDQV
YPLPIAQDHKRAFEGDRGPNTGGMGAYCPVPQISDQIVQTAVETIIKPVV
ATMAANGTPFTGVLYAGLIATATGIKVIEFNVRFGDPETQVVLPRLQGDL
AQVFQQLLTHQQPTLDWQADGVTLGVVVAAKGYPNQTPAIFQLAPTARFK
GANSQFSFAGVVATTGGLMSAGGRLYTAVYTAPTMAQARVQIEAGLQSVA
DPQSFFRRDIGFKSQM
>LSA0652 purE, Phospho ribosylaminoimidazole carboxylase (AIR carboxylase), catalytic subunit
MTDVAIVMGSISDWETMQETAQILTDLNVSYTKKVISAHRMPIEMIAFAQ
SAAEEGYQVIIAGTGGAAHLPGMLAANTVLPVIGVPIQSKALNGMDSLLS
IVQMPSGVPVATVAIGKAGAINAGLLATQICGLKTPTYQKALVQYKQALH
QKAVASNDQLN
>LSA0659 purF, Amidophosphoribosyltransferase
MLNEIRSLNEECGVFGVWGHPDANQLAYFGLHSLQHRGQEGAGIVTNDNG
QLLGYRDRGLLADVFRNPENLAQLTGEAAIGHVRYATAGSHGLENIQPFL
FDFADGQFALAHNGNLTNAVTLRRQLEDEGAILKSSSDSEILMHLIRRAA
GPDLHTKVKTALNQIHGGFAYVLLTQDSLIAMLDPNGFRPLSIGQMANGA
YVVASETCALNAVEAIFIRDVQPGEVVTIDRDGLHSDFFTTETTHSICSM
EYIYFARPDSDICGINVHAARKRMGKRLAAETGVDADMVIGVPNSSLSAA
SGYAEASGLPYEMGLVKNQYVGRTFIQPTQALREQGVNRKLAVVKSVVAG
KRIVLVDDSIVRGTTSKHIVKRLKEAGALEVHLRVASPPLKYPCFYGIDI
QTREELIASQQSVAQMCETIGADSLAFLSQEGLIDAIGLHQDAPYSGLCM
AYFNGDYPTPLYDYEADYQASLKQDKE
>LSA0662 purH, Bifunctional protein:phospho ribosylaminoimidazole carboxamide formyltransferase (AICAR transformylase)and IMP cyclohydrolase (inosinicase)
MKRALISVSDKTGIVAFAQGLVAADFEIISTGGTFSVLEKAGVPVTPIDE
VTHFPEMLDGRVKTLHPNIHGGLLAKRDEPTHMAALAEHEIAPIDLVCVN
LYPFKETIQKPEITQEQAIEQIDIGGPSMLRSAAKNFKSVYVVVDQADYD
ETLAQLQQDDVTYRRHLAAKAFRHTAAYDSLIAGYLSDADAVEFPEKLSL
TYDFKQALRYGENAHQKAAFYQSALPSAFSIAAAHQLHGKELSYNNIKDA
DAAIKVAAEFSEPCVVAMKHMNPCGVGLGTTIYDAWQKAFAADSVSIFGG
IIALNREVDVQTANALHELFLEIVIAPSFAPEALAILEKKKNIRLMTLDF
EQAAKADRFETVSVLGGLLVQERDRLTDQASELKTVTTKAPTEDEKEALL
FAQRVVKHVKSNAIVVATKGQTLGVGAGQMNRVGSVKIALEQALANGMQA
PFVLASDAFFPMDDSVAYAAEHGITAIIQPGGSIKDQDSIDMANQKGVSM
VFTNRRHFKH
>LSA0653 purK1, Phospho ribosylaminoimidazole carboxylase (AIR carboxylase), ATPase subunit
MTNLTKQILPGQVIGIIGGGQLGQMMTLAAKSMGFKVIVLDPQVDCPAGQ
VADDQIVAAYDDENQIIELAKRSDVVTYEFENVDATTIEKAQQLTQTPQG
TKALRIAQDRVLEKQFLATEKLPHAAFKVVTSISELTKAVAEIGLPCLLK
TARGGYDGKGQLVLRWPSDIEAARALLDFGVCVLEEMVTFDQEISVMISQ
NWAGQQALFPVIENQHRHNILHISICPARVPAAVAQEAKEIAQKIATEIE
LVGTLGVEFFVTPTGQLFVNEIAPRPHNSGHLTIEACDLSQFMAHIRGVC
NWPLQTPRLWQSAVMVNVLGQDVPGALAKSCQSTDWSYHDYGKAERKENR
KMGHITLLTDDLNKTLSEIEATQIWALPKEQTK
>LSA1556 purK2, Phospho ribosylaminoimidazole carboxylase (AIR carboxylase), ATPase subunit
MPVIYPGQTIGIIGNDQRAYKLALKAKEMGYRVAAIVTEQTQDSSLAAVL
DIQIEGDPQQYETLARLGDCCQVLTYTDESLDETLLEQLVQDYNVPQGSD
ALSMTQDRYLEKVFLSDLNINISPYVTVVDKTDIEQGVDSIGYPCILKPI
QRGFGRQYHQYLESPADLAKMDDTLELGAYLLESWVPKQQELAVMVAKDY
EGQVVTLPIIENQMQDQDLQLSITPARIDQDVAEEIERLATVIGQNLDYM
GIFGIEFFLTADMNIYVKRIVTAPHETGDVLNRILNFSQYEYHLKAICQL
AIGPSRLNNAGVCLRTTPEQWPLIQTQMKIKPDWYFNRCQTIGAQESGYI
TAVGHNIQPLLDNFEAAELI
>LSA0658 purL, Phospho ribosylformylglycinamidine synthase, synthetase domain
MVNNPTAIEIQQTKLYQQWGLTDSEYELICTKILKRLPNYTETGLFSVMW
SEHCSYKNSKPILKKFPTNGPHVLQGPGEGAGILDIGDGQAVVFKAESHN
HPSAVEPYEGAATGVGGIIRDIFSMGATPIAILDSLRFGELNDNQTKYLV
QEVVAGIGGYGNCIGIPTVGGEISFDPCYQANPLVNAMCVGLIEQKDIQQ
GKARGAGNSVLYVGAKTGRDGIHGATFASDEFAEGKATQRSAVQVGDPFM
EKLLMDACLELILQHSDWLVGIQDMGAAGLVSSTAEMAAKAGTGMILDLD
QVPQRETDMSAYEIMLSESQERMALCVRAGYEDQVIALFKGYDLDAVRIG
EVTTKEQYQLWHQGQLVADLPVAALTDAAPVYHKDQAKPERLATFAAQAP
YVPSVTDTQATWLALLKQPTIADKSSFYRHYDAQVKTNTVVLPGSDAAVV
RIRGTKKALAMTTDCNGRYLYLDPHVGGQIAVAEAARNIVAAGGQPLGIT
DCLNYGNPEKPAVFWEFDQSAQGIAAACETFGTPVISGNVSLYNEFNGEA
IYPTPMIGMVGLIRDIQDITTQDFKQVDDLIYLIGETDDNYAGSELQKMQ
QGTISDQLGHFSLATEKANQDLVLKAIQQGLITSAHDLSEGGLAVALSEA
TFKQGLGYHVQVDLASRQLFAETQSRFIVTVKAANQAAFEQISDQSAQLI
GRVTAEPIMHIQTKDEMIDLTVEAAKDAWEAALPCLMKSEA
>LSA0660 purM, Phospho ribosylformylglycinamidine cyclo-ligase
MTDAYQKAGVDVTAGYEVVARIQKKVGADNHNIGSFGGQYALEMAQYQKP
VLVSSTDGVGTKLMVAFAADQHATIGIDCVAMCVNDIVAQGAQPLYFLDY
LATGKTDPDKIEDIVAGVLEGCKQANMALIGGETAEMPGMYAAKHYDVAG
FAVGIAEQDALVTGETIQAGDVLIGLASSGIHSNGYSLVRKIFFEQNNLT
VASQLPELPGKTLGDWLLTPTKIYVEDLQPLLQQRVIKGAAHITGGGFIE
NVPRMLPADLAAHLTLGSWPILPIFKALQQYGQLAEMEMYNIFNMGIGMV
LAVAPEAAPAVLAQLNAKQEQAYQIGTVQKRQQAAVELVTAK
>LSA0661 purN, Phospho ribosylglycinamide formyltransferase
MRVAIFASGTGSNFEAIADNQRLQQAGLEIVQLVCDRPQAAVIEKAHRRE
VPVTVLAPRQFENRQAYEQAVVAQLAPLAIDYIILAGYMRIITPVLLGTY
PQRIINIHPALLPDFPGIHGIEDAYRAKVSETGVTVHYIDEGVDTGPIIA
QATVPVKPNDTLATLEARVHAVEHQLYPAVIYDLVQKNN
>LSA0657 purQ, Phospho ribosylformylglycinamidine synthase, glutamine amidotransferase domain
MKFAVLVFPGSNCDADLYHAIVDVCHEEAAYVSYTATSLAGFDAVLIPGG
FSYDDYLRSGAIAKLAPIMTAVVAFAKAGKPVLGICNGFQILTEAGLLPG
ALLPNRQTHFICETVTLQVENNDTRFTNQYAKGATIALPIAHGEGNYYCD
PETLAQLHANHQIAFTYTTDVNGSLDNIAGITNEAGNVLGMMPHPERAVE
VLLGSADGLGVFQSILTTLKSGVVTHGE
>LSA0656 purS, Phospho ribosylformylglycinamidine synthase
MYNVQVYVTYKDSVLDPQGQAVQGAIQRLGFEGISQMRIGKFFEMQVTGT
DQATVIEKVEAICDRLLANPNMEQYRYDVQLVEDAK
>LSA0954 pyrAA, Carbamoyl-phosphate synthase, glutaminase subunit
MKRYLILEDGTVFSGFGFGAPTISTGEIVFNTGMSGYQETITDQSYNGQI
IAFTYPLIGNYGVNRDDFESIKPTCKGVVVHEVPRLANNWRMNMSLDDFL
KQKKIPGIWGIDTRALTRRLRDKGTMKASIVDAADDHAFDQLKALVLPKN
QVQQVSTAKPYPSPATGRNIVVIDFGLKHSILRELSKRNCNLTVLPYNAT
AEEILSLDPDGVMLTNGPGDPEDVPEAIEMIRGIQGKLPIFGICLGHQLF
ALANGAKTYKMKFGHRGFNHPVREIATNRIDFTSQNHGFAVDADSIDPQQ
LLVTHVEINDHTVEGLRHRQYPAFSVQFHPDAAPGPHDAVHLFDEFIDMI
DDFNRRQK
>LSA0955 pyrAB, Carbamoyl-phosphate synthase, catalytic subunit
MPKRTDIRKILVIGSGPIVIGQAAEFDYSGTQACLALKEEGYQVVLINSN
PATIMTDKTVADTVYIEPITLDFVTQILRKELPDAILPTLGGQTGLNMAL
ELANCGILAELNIELLGTKLSAIDQAEDRELFKNLMNQLNEPIPESAIAH
SLDDAQEFVKQNGFPVIIRPAFTLGGTGGGIAENAGQLKTIVKNGIALSP
VGQVLVEQSIAGYKEIEFEVMRDRNDNALVVCNMENFDPVGIHTGDSIVF
APVQTLSDREVQMLRDASLKIIRALKIEGGCNVQLALDPNSERYFIIEVN
PRVSRSSALASKATGYPIAKMAAKIAVGLTLDEIYNPITGTTYAQFEPML
DYVVAKIPRWPFDKFNKGDRQLGTQMKATGEVMAIGRNIEESLLKAVRSL
EIGTAHLELDGLTSVSDNDLVQRIIHPQDDRLFYLAEALRRGYLIQELAE
LTKIDLFFLDKISHIVELEEQLRSEKGDVELLEIVKKNGFSDEKIAKTWQ
ITPIQVRQMRQESGIQPVYKMVDTCAAEFESQTPYYYTTYEQENESLVSA
KPSILVIGSGPIRIGQGVEFDYATVHCVQAIQKAGYEAIIMNSNPETVST
DFSISDKLYFEPLTLEDVLNVVELEKPEGVIVQFGGQTAINLAAPLEENG
VKILGTSVANLDRAEDRDLFDQLIQELNIPQPVGKTATNAPDALTIATEI
GYPVLIRPSFVLGGRAMEIVHTPEDLTHYMQEAVKVSDEHPVLIDRYLMG
KECEVDAICDGQEVLIPGIMEHIERAGVHSGDSMAVYPPQNLTEDQKAAI
IDYTTKLCLALDCHGLLNIQFIIQNDEVYVIEVNPRASRTVPFLSKVTQI
PMAQLATQLILGSTLAELKSPTGLLPAGPLIHVKAPVFSFSKLTRVDSLL
GPEMKSTGEVMGTDVTMQKALYKAFEASGMHLPSHGNVLMTVTNQDKAQA
LALAERFREVGYQIIATPGTTQQFKAAGIPVQQVDKINATSGDLLDKIKA
GHIQLVINTTGLNEAPQVAKDSIVIRQTAIEHGIPLLTSLDTTDAILTVL
ESQSLLTKPL
>LSA0952 pyrB, Aspartate carbamoyltransferase (Asparate transcarbamylase)
MTNQTAIVSVEQLTNSSVLNLIERAEAFKQGATCELTRPVYAMNLFFENS
TRTKTSFEMAERKLGLSVMSFEAETSSVSKGETLSDTLKTVQAIGVDFVA
VRHPQNYYYDDLLADPAFHLALANGGDGSGQHPSQCLLDMMTIHEEFGHF
DGLKVVICGDLRHSRVAKSNMQLLKRLGAQLYFAGPEEWFTAEFNDYGQH
VALDSILDQVDVVMLLRIQHERFDSAETMTDEAFHVKYGLTAQRAAQLKA
STIWLHPAPVNRDVEIADELVEAPQSRIFKQMHNGVFMRMAMIEYLLKQK
NLIKD
>LSA0953 pyrC, Dihydroorotase
MYRLIQNGQLLIDDQLVKRDIAIDEKGRITAIEAQITPTDEPTETIFDAQ
GALVSAGLIDGHVHFRDPGFTDKETLQTGSQAAAHGGYTSVIAMPNLNPV
PDNLSDFKTLVARNQTETSVHTYQFAPITGDLVNNDLVDMPAFKAAGAAG
FTNDGHGVQDAQTMYLAMQQAAAIDAPIVAHVEDISLVNGGVIHDGAAAK
RLNVPGIPSVSESAQVARDIELARATGVHYHICHISTKETVALVRRAKAD
GVNITCEVTPHHLLLDDRSIISDDTMLKMNPPLRTLADRQSLWAGLMDGT
IDVIATDHAPHTAAEKSQSLLQAPFGIVGSETAFSLLYTHLVVNGPFSLA
QLLAKMTTVPAQVFNLPAAGQLRVGDQADIAVFNLTQPTTIQATDFQSKG
HNTPFIGETVLGGTELTLVAGQVAYQRSK
>LSA0957 pyrDB, Dihydroorotate oxidase, catalytic subunit
MTSDLRVSLPGLELKNPIMPASGCFGFGQEYGRYYDLNLLGAFIIKAATK
EPRLGNATPRVAETPSGMLNAIGLQNPGIEAIMAEKLPWLAERYPDLPII
ANVAGNTEADYVAVCERISQAPNVHAIELNISCPNVAHGGLEFGTSPEAA
ATLTKACVAVSQVPVYVKLSPNVTDIRPIAKAVEAAGAAGFSLINTLVGM
RIDPKTRQPILANQTGGLSGLAIKPVAIRLVHQVRSISNLPIIGMGGVAT
AGDALELMAAGANAIAVGTANFSEPFACPNIIKALPDELAKYDLHDFKTF
AVNQEVL
>LSA0959 pyrE, Orotate phosphoribosyltransferase
MTTIAEQVAQALIDIKAVSLSPNQPFTWASGLKSPIYCDNRLTIGYPKVR
KLIASQLAAAIKAQFPEVEVIGGTATAGIPHAAWIAAELDLPMVYIRSKP
KDHGQGRQIEGPFTAGQKMVLIDDLISTGGSVLQAAQAAQKEGAEILGVF
GIFSYELAAGRKNFEQAGFPLMTLSNFSALLAVEQAADNLTPEQATSLNE
WRQDPQAWSDAH
>LSA0958 pyrF, Orotidine-5'-phosphate decarboxylase
MTNPVIIALDFPNWQKTDQFLQQFPKDEALFVKIGMELFYQEGPQLIKTL
KARDYRIFLDLKLYDIPNTVQSAMTVIGQLGVDYTTIHAAGGQTMLQAGA
AGLKAGAKQANVKPAKLLAITQLTSTNEAQMQQEQLVSVSLPESVAHYAQ
LAQQSDCDGVICSAQEITTIKSKTATDFLCVTPGIRPATSQNNDQKRAVT
PLEAAQMHSNGIVVGRPITQASDPYQAYQAIKSEWESFK
>LSA1629 pyrG, Cytidine triphosphate synthase
MTKYVFVTGGVVSSLGKGIVAASLGRLLKNRGLKVTIQKFDPYINVDPGT
MSPYQHGEVFVTDDGTETDLDLGHYERFIDNNLNKYSNVTTGKIYSEVLR
KERKGEYLGATVQVIPHITNMIKEKIMRAATTTDSDIVITEIGGTVGDIE
SLPFLEALRQMKADVGAENCIYIHTTLVPYLKAAGEMKTKPTQHSVKELR
GIGIQPNVLVCRTEKAIPDDMRNKIAQFCDVEPEAVVESRDAESIYDIPL
LLKNQGLDDFVLNHFKMTAPEADMTEWIDMLHTIKNLEGTKKIALVGKYI
ELQDAYISVNEALRHAGYVYNTDVKVTPIQSEDITKENVAETLAGFDGII
VPGGFGDRGLEGMILSIQYARENDVPYLGICLGMQMASIEFARNVAGITD
ATTGEVHPDAEHKLIDIMSDQKDLENMGGTQRLGLYPCKLKPGTKTAEAY
DNQSVIQQRHRHRYEFNNEYRDLLTDKGLVFAGTSPDNRLVEVIEIPENK
FFVAAQYHPEFLSRPNKPEGLFKAFIGATM
>LSA1263 pyrH, Uridylate kinase (Uridine monophosphate kinase) (UMP kinase)
MTNTKYKRIVLKVSGEALAGEQGFGINPEIVKVVANEIKSVHDLGVQIAI
VCGGGNIWRGVTGEQMGMERAQADYMGMMATVMNALALQDNLESIGVPTR
VQTSIEMRQIAEPYIRRKAVRHLEKGRVVIFAGGTGNPYFSTDTTAALRA
AEIDADVILMAKNNVDGVYSADPNTDPSAVKFDTLTHLDIINKGLQVMDS
TASTLSMDNDIPLVVFNLNEADNIKKVVEGANIGTTIEGEE
>LSA0951 pyrP, Uracil:cation symporter
MTKSTYRNPDAVLDVNERPTTGKWIGLSIQHMFAMFGSTVLVPILVGLNP
GIALFSSGVGTLMYLLITKGKIPAYMGSSFSFIVPMLALMKTTGYPGIAQ
GTMAVGAVYLIVSVLVSLIGSGWIDKALPPIVVGPIVMVIGLSLAGTAAK
QATINAAGNYDLKFFAVAILTLLITIAFNMYLKGFMSLIPVLLGIVSGYI
IAVLFGIVDFQPVLNAPWFKVPDFQVPFVTYKPGLYWGAILSMAPIAFVT
MTEHMGHIMVLNKLTKRNFFKNPGLHRTLAGDGTASIIAAFVGGPPVTSY
GENIGVLAITKVHSVWVLGGAAFFAIIFGFIGKLSALIQSIPAPVIGGIS
FLLFGVIASSGLRVLIDNQVDFDKKRNLMIGSSILVIGIGNAYLQLGQYQ
FSGLAIATVLGIAMNLILPQKSKSEIELEAQQND
>LSA0950 pyrR, Bifunctional protein: uracil phosphoribosyltransferase and pyrimidine operon transcriptional regulator
MVKEVVDSTTMKRVFTRITYEIIEQNKGISDLVFVGIKTRGVFIAERIAK
RLEQLEGVTVPVGTLDITLYRDDQHDLNSHNEPQLNGNDIPVDITDKHVI
LIDDVLYTGRTIRAALDALMDLGRPKKISLAVLVDRGHRELPIRPDFVGK
NIPTALNEQIKVAMQEIDEHDGITIEKLN
>LSA1138 tdk, Thymidine kinase (deoxuuridine kinase)
MAQLFFRYGAMNSGKSIEILKVAHNYEEQNKSVIILTSGIDNRDGVGIVS
SRIGLKREATPIFSDTNIYELVEATNPDAACVLIDESQFLERHHVIEAAK
VVDDLNIPVMAFGLKNDFKNELFEGSKYLLLFANKIEEMKTICWFCRKKA
IMNLRMNNGLPVYTGEQIQIGGNEAYYPVCRKHYFNPPIQEEIEKEG
>LSA1001 thyA, Thymidylate synthase
MSEQVYLDLARTILEEGHYKGDRTNTGTYSLFGYQMRFNLQEGFPLLTTK
KMPFGLIKSELLWFLKGDSNIRYLLQHNNHIWDEWAFERFVKSTDYTGPD
MTDFSHRAQDDADFKVVYQEQMRLFNDRILADEGFAKQYGELGDIYGKQW
RAWQTRSGETIDQIKNVIEMIKTNPDSRRLIVSAWNPEDVPSMALPPCHT
MFQFYVNDGKLSCQLYQRSGDVFLGVPFNIASYALLTHLIAHETGLEVGE
FIHTLGDAHIYSNHVTQVKTQLARSMHAAPKLWLNPDKKSIFDFDVADIK
VENYESEPAIKAPVAV
>LSA0340 tmk, Thymidylate kinase (dTMP kinase)
MVGKLITFEGPDGAGKTSALEAVVARLQKEVSQEIVVTREPGGNPISEQI
RQIILDVKNTAMDDRTEALLYAAARRQHIVEKIQPALAADKLVICDRFVD
SSIAYQGAGRGIGEEAVAQMNLFATDGLTPDLTLYLDVPSEVGLARIKQH
RQNQYDRLDQEKLAFHQKVRQSYLKLAQAHPDRIKTIDASQPLEAVVTQC
LQVIAQANLHLFEV
>LSA1373 udk, Uridine monophosphokinase (Cytidine monophosphokinase)
MTSQKKAPIIIGVTGGSGSGKTTVSQAIAQKFANHSVMLLPQDAYYKHQD
GSFEERQETNYDHPDAFDTDLLIEQATMLKNHQPIEQPVYDYKIHNRTDE
VVHVEPQDVIILEGILVLADARLRDLMDIKVYVDTDDDIRLLRRMSRDME
SRGRSFDDIVMQYLKTVKPMFHEFIEPTKRYADLIVPEGGNNRVAIDLLV
TKIQSILNMND
>LSA1133 upp, Uracil phosphoribosyltransferase (UMP pyrophosphorylase)
MAKFTVLNHPLIQHKLTIIRNKNTGTKVFREVANEIAELMVYEITRDLAM
EDVEVETPMGPAIEKQLSGKKLAVVPILRAGLGMVDGVLELIPAAKVGHI
GMYRDEKTLQPHEYFVKLPTDIDQRQLFIVDPMLATGGSAIMAIDALKKR
GATSMRLVVLVAAPEGVKAVQEAHPDVDIYAAGLDDGLNEEGYIYPGLGD
AGDRLFGTK
>LSA1557 xpt, Xanthine phosphoribosyltransferase
MRLLEERIKKDGQVLGEDVLKVDNFLNHQVDPELMAAMGEEFKRLFEGAP
ITKILTVESSGIAPAVFSGLAFHVPVVFARKHKSLTLQDNMYSATVYSYT
KKVNNHISISKKFLNENDRVLVIDDFLANGQAVEGLLEIIDQAGAQLEGV
GIVIEKTFQKGRELLDQRGIHVESLARIAAFEQGEVVFLDENNEN