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# Neorickettsia sennetsu str. Miyayama, Miyayama

>NSE_0085 cytidine/deoxycytidylate deaminase family protein
MDKKFMELAMSVARQSDCEVPVGAVLVRQGAVIASSGNRVFRDSDPTAHA
EMFVIREAIQRLGVKFLVDFELYVTLEPCPMCMYAMSLSRVGTLCFAAYD
EKRGAISNGCLGTGTYFHVPIIYEGLMEDEAKELLSSFFRILRN
>NSE_0460 putative deoxyguanosinetriphosphate triphosphohydrolase
MLSSYSSFPERSKGRLFLEKEDPQRDCYQRDRDRLIHSSAFRRLMYKTQV
FSHCGDDHYRTRLTHSLEVAQIARSIARLLGLNEDLTETIALAHDIGHPP
FAHIGEEALQEVAAEHYRFEHNAQVLRILGEFEHQYMDFDGLNLTWETIE
GLAKHNGPIQEPHQIIEEYNGLLDLELNKQPSLEAQIVSLADDIAYSSHD
IDDGLLSGVITYQDLRHLPIIGENILKFEKTFPEASKSQVMYKARRRMIR
FLIYDVVDVARENIKRYLLKTVDDIRELGFPAANFSEKVGKEMKEIKAFL
YNNLYFYYSIRKSRVKLKRIVKELFEVFFHDPQCLPKDYYERFRIADSMN
KKAQLVCDFIANLTDSSAIREHRQFFSTCVLERDY
>NSE_0812 putative phosphoribosylformylglycinamidine synthase II
MQAIIEVRKPYSDPRITTLESNGVINIREVVDAYRFYSTDCSLKDNLLEI
AHALTNHVSEQFRCFIYEPDKNKIEILETNKTSYHEGNSILWDFRRCYTS
NFWIIEKQPLQGVKNSLAEVILGIVSTLLQQKGINAIEQCIQVETSLLMI
GTGRLPDLNLLYNPMIEELSLEKVHSKKVAFCYSHEMDSVTFSGDTKDLT
LEELASFNCQNALNLSDIQLSKIVEYFRLQEGRSYVRDIELETIAQTWSE
HCKHNIMSYPIDDLQEGIFRGYIKKSTETIIRNNPNHICASVFTDNAGAI
WFDKDYLICVKVETHNSPSALEPFGGAMTGILGVNRDILGFGLAAKPIAN
YYAFCVEDPDTENQDLYHDSHKTKPKLDSRTILKGIIRGVNAGGNCSGIP
TPQGALYFSSAFRAKPLVFVGCAGIIPAKIAEKESWVKAPRDGDLIVIAG
GRTGRDGIHGATFSSTGITDSNVKGTEVQLGDPFTQKKLSDAIIREVRDA
DLCNAITDNGAGGLSSSVGEMGKNGFVVHLEKVLLKTIGLAPWEIWISES
QERMTFAIPREKLEAFGRIMTKHGVEFAVIGEFNRSGRGLITFEGKTVFD
LSLCFLHDGNPTIHLQTKKPREMRGQPHVSFSSLEEAIRDKNVCSRKFIA
EQYDHEVQGTSILKPLQGKNEIFSDVTAIKPLYNSRKCIGQSQDLAIITR
DPYLDTCSSIEKAVRNLVTIGVNPQKIALLDNFCWSDSNDPEKLWLLKEA
GRACHDTSIALGTPFISGKDSMFNDFSGYTTSGAKVKVSNIPSLLITAVG
IIDDYEDIVSLDAKYPEDLIYLIDMKVEVKRALEIFGRYYSALKNQLVAS
AIPVGLGGRLVSIAKMLIANGHGGTIFLENNKDNLEKSHEIVVTVAPKNE
LAFRETFLDTEITKIGTVTREAAVEIGKSTKIEVDALLSLYKRILL
>NSE_0964 putative deoxycytidine triphosphate deaminase
MPVMPDQWIKSKALESRMIEPFVSSKISTGVISYGLSSYGYDARVSNKFK
IFTNLAVSQVDPKNFDESMLIERTGDFCIIPPNSFALGCTIEYFRVPRGV
IVICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKIYSNEGV
CQMIFLKGSTNCDVSYKDAKGKYMGQAGITLPIVK
>NSE_0413 HIT domain protein
MSMYDQQNVFARILRRELPSRVVYEDDGVLAFYDAFPKAPVHVLVIPKGQ
FVSFSDFISTAPIEVASFFSKVGHVIDLLGVKEAGYRLITNHGEDGGQIV
KHFHVHILAGKKMSDIA
>NSE_0205 hypothetical protein
MMSDFMRVLCLRFIEKFTFPSICFLLFLVPALAVPRIGIFSTDLYVYERE
AFGVEKFFKLPEALGHDFEVVMVDYNLIHSDYLKKNKKVPLEKLLENALE
AKGVRHLILPGDVYNVHMSPLHPTSTKSHMYKALLGLVKENKVSIFGICG
GMQQFFNADGIRILNLLQMGITEPHKKQKDPHSASNSGPHPDRLIRKVMV
NPASKVGAIISQVPLEVTANGWLILYVPELHSEGVALDKANLKTLRDFGY
KVVGFAEDGVIEIVEDQYGNFYFQPHIESFLLEFTPEKINELPEKLLSSV
DAAKYLLLHFVGS
>NSE_0448 putative phosphoribosylformylglycinamidine synthase I
MASVLVLSGYGLNCEDETLRAFELSGFAGSVLHLDDLLNKPNKLCNHQVL
AIPGGFSFADNTGAGNAFACKTIPLLEEVENFLNKDKLVIGICNGAQILT
RLIKDLEVTFEANTSNQYQCGWQDIEVPESDSIWMRGIHEIRLPIAHGEG
KLLPLDKTNLKVSVAMRYKQDVNGSYNRIAAVTAYGGKMLITMPHPERAV
SLVQTDDYYLVREEYRRRYLPTPKDGPGMRIFKNAYDYFH
>NSE_0286 adk, adenylate kinase
MNLVMFGPPGSGKGTQSSRICSYVSASVVDCGKLLRVAALTMRQSEDLKA
GKLLPDELVIGVVREKLRELIKVGDNFILDGFPRSVVQCHALFEMSSELE
FEISCLVKFEVSEREIFARLLDRLVCSACGALHDVVLGRCVSCGSVECER
RSDDLKVEIIKKRLMLYGAVERDIVNLFRSRSIKVLSIDAGRSVDEVAAD
LRTQLLMFI
>NSE_0502 carA, carbamoyl-phosphate synthase, small subunit
MSYDSCLAFAGGECFFGFSYGKRDVAVGEVCFTTGMTGYQHTITDPSFSG
QIILFAFPHIGNVAINSCDNESSRIFARGLVFREGPQDFLHHLRMRSFSS
WLEDNNVTAIYGVDTRAITRLVRLKGNQGGIIFPVNDISIDEAILLLRET
EDMNGNELATSASGNARCSPCCVGDKRKKVCVVDFGIKDGIVRNLEKYFT
VVVVDGKKGFSSALESEDFAGIVLSNGPGDPSATYLQLCEDFSRVLTSNL
PVLGICLGHQLLLLAFGCKTKKMLVGHRGTNHPVINLETQRVEITSQNHG
FVLDESTLNSKDIIVTHRSLFDGSVEGIKIKDRKIFSVQYHPEGSPGPHD
SHYIFSKFFNEISSQ
>NSE_0222 carB, carbamoyl-phosphate synthase, large subunit
MQEKKSTILVIGAGPIVIGQACEFDYSGTQACRILRKCGYKVVLINPNPA
TIMTDPDTADVVYIEPINIGIIERIIAIERPDKLLPTVGGQTALNIAIEL
FDRGILSRYGVELIGASKRVIENAEKRSVFNRLMGEIGLQVPKNTMVTHV
NEIEKAFEFIGVPAIIRPSFTLGGLGGGVATTKFDFFTIINNGLKFSPVS
EVQVDESVLGWQEFELEVVRDSVGNSIIVCSIENTDPMGVHTGDSVTVSP
ILTLRDEEYQEMRDAAFKVLDCIGVTTGGANVQFALNPENGELRVIEMNP
RVSRSSALASKATGYPIAKVAAQLAAGLTLPEIYNDAVPTIPASFEPAMD
YVVVKIPRFNFEKFFHAEERLSSSMKSVGTTMAIGRCFQEALQKAFSSLE
QGLDGLNTVLDLNVSRKVIERKLRSLIPNKILVIADAIRAGFQIKEIVYL
SKYNEWFLLQIDELVNLENEIKSGNFSPNRLLIWKKKGFSDSRIASLKGC
DEAFVRSTRKKMAIRPVFKRVDTCAAEFESDIKYLYSTYEGDTVTQPECE
AYPSDRKKVIVLGSGPNRIGQGIEFDYTCVHAISAIKELGYEAIMVNCNP
ETVSTDYDISDKLYFSPMNVESVLDIVEKESERGELLGVVLQCGGQTPLK
LARAMHENNVRIIGTGFASINTAEDRKSFNSLVAELEMLQPENAIVLARE
EIAKNVKKIGFPLIVRPSYVLGGESMQIIYDDAMLEDYLERHTQLFSGSS
LLLDKFLVNALELDVDAISDGEDVYIAGIMEHIEEAGVHSGDSAFVFPPQ
KLSEEILERIKSCTKKVAIALNVVGFLNIQFAIDGRDVYVLEVNPRSSRT
IPFVAKALGIPVARIATKVMLGMKLRDFQLKGYEDYVKHVFVKQPVFSFE
KFPESDVLLGPEMKSTGEVMGVGDDFDTAFAKVCMASMRKLPTSGKVFFS
IRDEDKLKSVEVAKILSELQFTILATKGSAAFLEKHNIDAVTVNKVKEGS
PHVVDMIMNSEISLVINTSSHVLESVRDSMSIRSSSIINQIPCCTNIHSA
LALVRGIKKIVKCKLPVYQLSYV
>NSE_0957 dut, deoxyuridine 5'triphosphate nucleotidohydrolase
MQEHAKILLLPHGKDLEIPRYASKGSSGLDLRAAIEGSMTLKPGMFELVP
TGICIELPEGLEAQIRPRSGLAAKFGITVLNSPGTVDQDYRGEIKVCLVN
LSKNEFTINRGDRIAQMVIAKVEQILLVEAEEIGETERASGSFGSTGTE
>NSE_0726 gmk, guanylate kinase
MRKGILFIISSPSGGGKTTVADFLVGQDLSIKRSISFTTRQPRGEEKDGI
DYYFVSKDEFNRLLQEGEMLEHATVLQNQYGTSHRYIEETLALGIDVLCC
IDWQGAEQIRKKTNCISIFLLPPSLQKLKTRLTSRGTDTADVIEYRLKVA
LEEIQHFSKYDYVLVNDDLTETKQKVLSIITAEREKLVQNHRVVECFVAS
LLEQTI
>NSE_0887 guaA, GMP synthase
MMPEIAIIDLGSQFTQLIARKLRENGCCSCIYNPSGFTFSNDIKGVILSG
SHQSTSEYANYRDLIAMVLSLNSTHGIPVLGICYGKQLLSDFLGASVVSG
KNREYGRARLQIVAESPIVSNISASDFTVWMSHGDAVVTLPCGFKCVAKT
DDCQFALIADENRKIYGFQFHPEVSHTENGGVLLRNFISIAGVENTWDLQ
VFSEEEKRMVVATTGDAGVLAAVSGGVDSTVAAKFMHGAIGERLHCIFVD
TGLLRKNEANEVKESFSSLGIPLKIVFAADRFFKKLAGVADPEQKRRIVG
ETFIQVFEEEALKIQGVEFLLQGTLYPDVIESGGGGSHTIKSHHNVGGLP
KKMGLKLLEPFRLLFKDEVRAIGRQLGVSEVLLMRHPSPGPALAIRILGE
VTQEKVAVLQDIDEIYISTMKEYNLYSHIWQAFSVLLPVCSVGVMGDKRS
YNYVCALRAIVSHDGMTASAYPFEAHDDDKLRFLSFLNEVATKIPNRVSA
VSRVVYDITSKPPATVEWE
>NSE_0560 ndk, nucleoside diphosphate kinase
MKRTLSILKPDVISRNITGKVNAYIEAAGLQIIAMKQLHLTRIQAEAFYV
VHKDRFFFNDLVNFMTSAPVIVQVLSGDDAVHRYRKLMGDTDPKKAAKGT
IRGDFAESIDANCVHGSDSEENAKNEIAFFFSRCEIFDR
>NSE_0411 nrdA, ribonucleoside-diphosphate reductase, alpha subunit
MLDPSPIFHHDHDEKKIHTLHARDSFLTDFGKAVLKDRYLQNGEDYQGLF
ARVAKYYSDDPKHACRLYDYMSNLWFMPATPILSNGGTSRGLPVSCFLNE
TEDSLEGIVGLWNENVWLASHGGGVGSYWGNLRSIGEKVKCSGKTSGIIP
FIVVQNALTLAISQGSLRRGSSAVYLPVNHPEIIEFIDLRKPTGGDPNRK
ALNLHHAVVINDDFMKAVLEDKEWDLISPKDGSVIATVGARGIWIRILTA
RLETGEPYILFIDTVQRLRPDVYKNLNLDVKMSNLCSEITLTTGKDHLDN
HRTAICCLSSLNLEKFDEWEHNEQFVRDVMHFLDNVLEDFIRKAPDCMHR
ARYSAMRERSIGLGVMGFHSFLQSKGIPFESAIAKSVNLKIFKKIKHEAD
KISKEMALERGPCKDAVDCDTMERFVHKIAVAPTASISIIAGNTSPGIEP
YAANVFTQKTLSGSFVVKNKHLAALLERKGKNTDCVWSSIISNEGSVQHL
DFLDENEKMVFRTAYEMDQRWVIELAADRTPYICQSQSVNLFLHSNIHKK
ELSNLHFLGWKKGLKSLYYCRSKSIQRAYKISQEYKHKSDTPSPVGESDD
CIACQ
>NSE_0520 nrdB, ribonucleoside-diphosphate reductase, beta subunit
MSLLEPRLSYKPFQYDWAYQAWEIQQKIHWLPEEIPMADDVQDWHHKICG
TEKNLLTQIFRFFTQADVEVHDCYMRHYAGVFKPPEVCMMLTAFANMETI
HIAAYAHLLDTVGMPETEYLAFTKYKQMKEKCEYLKAFKMDNPTEIAKTL
AVYGAFTEGLQLFASFAILLNFPRFNKMKGMGQIIAYSVRDETLHSNSIT
KLFRTFLLENNIDKFKLEAEIREICNAMVHHEDAFIDLAFEMGDVEGLKA
SEVKEYIRYIANLRLKQLGFSEIYEQKVNPLLWLEAVLNTVEHTNFFENK
ATEYSKAATKGTWDEAFNFSDA
>NSE_0816 prs, ribose-phosphate pyrophosphokinase
MKVLMGSKAGKLGQEIASLLNLAVVRAQANRFPDGESDVLVHHEDVIPGT
KVLVIQSLCSDADIMEFLFIVDALNRLGVRDIALVSPYFGYARADRIVAP
GSAISAKVVARLIGERISLLFVLDVHFPQFEGFFEIPVYNILPWTLLKES
VHVGHNMALVAPDVGAVKKLKPLSEELGTNLVIMNKRRPRACLSEVTEVV
GEIHGRDCIIVDDIVCGGGTLCNSAAKLKELGAKSVAAFVTHGVFSGSAR
QKIMDSQIDRIVVTNSIPGPGCEAKGKIEIISAADLLARKIHSVYLDVNT
KSPNC
>NSE_0225 purA, adenylosuccinate synthetase
MDAAVIGLQWGDEGKGKIVDHLAGDFDSVVRFNGGNNAGHTVIVGERTYK
LRVLPSGILREDVVSVIGNGVVLDPQGLLDEIHLLKKEGVQIHPGKLLIA
DNCHLVLPIHRELDVLFEQKQKLGTTKCGIGPCYQDKVARRGIRLCDLRS
EEQLRKTLAGLSYYHNIVRKGAGLQEVCQEILFASLFAMRDELLCYAVPP
CELQGILSGKSKLYEGAQGMLLDIDHGTYPFVTSGSSGLGQVMNGAALGC
VNRVIGVMKGYVTRVGEGILPTEQDNAFGSELQKLGKEVGTVSGRIRRCG
WCDLPLVRYVNAVAGVTEIVITKLDVLDSFNEIFLCCAYKGKKGKLIEIC
SPSKLCYSKYEAQYIVMKGWRSSTVGVTSFCDLPDGAKSFVETIEKCLDL
PVTMISNGPERTQVLHR
>NSE_0059 purB, adenylosuccinate lyase
MIPRYSREVAASIWRDDTRFSLWLEIELLACEAQARLGNIPQESLSVILE
KAAFDIERIGFIEKEVKHDVIAFLTSVAEFVGPDARYIHMGMTSSDVVDT
AFSLQLRRAGTLLLEGLDKVTEALRERALEHKNTICVARTHGIHAEPITL
GLKFARFYQEFKRNRLRLSQVIKEISVCKISGAVGQFGNIDPFVQEYVAE
KLGLEPEPLATQVIPRDRYAVFFSTLALIASSIENVATEIRHLQRSEVLE
CSEYFSPGQKGSSAMPHKKNPILSENLTGLARIVRSTVIPFLENVSLWHE
RDISHSSVERVCAPMACVTLDFALERLSTVIRELVVFEKNIEKNLNLLGG
LIFSQKVLLALIESGKTREEAYHIVQENAMKSWNDTSTSFVENIKMDKRV
TFQEVDKLFCYESYLRHLDYIFEHVFSASEVS
>NSE_0852 purC, phosphoribosylaminoimidazole-succinocarboxamidesynthase
MRERRKIYEGKAKILFSFPDNPNLVTQHFKDDVTAYNNRKHSVIPGKGVI
NNYISAFFMQNLQNVGIKTHFVKVLNMREQLVKKAELIPIEVVIRNIVAG
GLAKRLGLEEGMILDAPLIETYYKSDSLGDPMVTDDHILSFNWLKLSEIE
EMKVMAWRINDFLSGALSSAGIILVDLKLEFGFYDDQIILIDEISPDTCR
FWDTETKEKMDKDRFRRDLGGVSKYYREVARRLGILNGSF
>NSE_0924 purD, phosphoribosylamine--glycine ligase
MQLKKVLIVGNGAREHALITKIKESPMLDKVYTTNSNFGQFAEYLDTNLE
NYLYTSATCKTEGIDLVVIGQEEHLARGITDALTAEGIPVFGPTKNAAKL
ESSKFFAKEIAEMNGIPVARYSFCSSINNLKKQIENIGSFPLVIKADGLA
SGKGVIVCETMGEALEAGEAMLNGLFGEAGRNIIIEEFLYGQELSYFVLV
DGQTILPIGHARDHKQISYNGKKYNTGGMGAYSPVLLSKKTEQEILGKIV
YPTINALSAINVQYKGVLFAGLMLTNSGPKLLEYNVRFGDPETQAILPRL
NADLLDLMLKTLDGGLDRATISFKKEVCMSVVLATRGYPVSYETGYRIDN
IEKALQSVEGLQILNAAVRYDAEGRMISNGGRVLNLVVSAPTLLECKRKV
KRGLELIDWKEGVYLDELVVV
>NSE_0235 purE, phosphoribosylaminoimidazole carboxylase, catalytic subunit
MGSEKVAIVMGSTSDYPTMQHAEKILEQLVVHFETYVISAHRTPARLYEF
SKNAADKGIRTIIAGAGGAAHLPGMIAAISDIPVLGVPVESKTLNGLDSL
LSICQMPAGTPVGTLSIGKAGAENAALLACRILALQDKDLQDRLRIWIRK
QTETVPERP
>NSE_0194 purF, amidophosphoribosyltransferase
MVSRDQSGWLTEKCGVVAVVGTPNAVELSLLGLHGLQHRGHEAFGIAFVH
NGDVGVVHRFGRIMSVNPVDLSIPSAETVIGHVRYSTSGGSDFSQPVYLK
YRSCEVVVAHNGNLTNTDEIRTKLESEGCVLQSEVDTEVIAHLIARSSRK
TPTEKIVDALQQVEGAYSLLLFVGGEIFAVRDPHGVRPLSLGKLGDGIVI
ASETCALDMLKATFVRDMAPGELLQIKDGKLTSLFPFKRMEHKFCIFEHV
YFARPDSVLEGRSVYASRKEIGKELARESKIEADMVVPVLDSGVVAALGY
SEESNLPLELAITKNHYSSRSFIEPTPERRNMRVKLKHNANRFLLKGKKV
VLVDDSIVRGTTLKHLITMLWEAGTSEIHVRISSPRILNPCYYGVDTPNR
KDLISANLPLGEMSVYLGATSLYFLTLEGLYKAVSGSEKRIGFCDACFTG
DYPIKCLGTSQST
>NSE_0185 purH, phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
MIKRALISVYDKTDLLPLAHKLQAANVEIIATGKTHKYLLENQIRAINLS
DYTHQPEILGGRVKTLHPLIHAGLLADPALHEAEMQTLTIKQIDLVVVNL
YPFEKCVNSGAPESEIIENIDIGGVSLLRSAAKNFKNVCVLSDPSDYGTF
DVNPTLSFRTKMARKAFARVARYDCKIAEWFASSTSLPEVLNLSVMKKND
FRYGENPHQNASFYSNGEFPLTKLQGKELSYNNLLDLDSALSIVTNFTEP
TCAIIKHSNPCGVASHKSSLEQAYEKALAADSLSAFGGVVALNQIVTRNV
AEKLLNTFFEVIVAYGITQDAIFLFSNKPNLRILTCKGYTAPEKHMLSLL
GGLLVQSGNTKLFQDFDIVTKRQPTNEEVNQLIFAWKICKYVKSNAIVTA
HDYTTVGIGAGQMSRVKSVEIALGKSKVGQPLAMASDAFFPFADSIELAA
KSGVKSIIQPGGSIRDKEVIEAADHHNIAMIFTRMRHFRH
>NSE_0965 purK, phosphoribosylaminoimidazole carboxylase, ATPase subunit
MDLYSRKMQRIGIIGGGQLGKMTAIAAYNLGFKVCVLAEKENSPAIDVAR
DYVVSPFLDRSGILNFVEHVDAITFESENIPTETLDLLHDKFDVPNTKAI
KVAQDRFLEKEFLRKNGIPTTEYWYIEKEEDLDSVDFPAILKTINGGYDG
KGQFLLEDHDYVRREAGNLKFPLIAEKLFRISKEFSIIVSRNETGSVCFP
IAENVHVNGILKTSSVPAVLPHHVALEIKNIGFQIADLLEIKGLLCVEFF
LDEDNKLVVNEIAPRPHNSGHWSMDCCDIDQFEELVLAITGNKLKKPNLV
VPCTMKNILGNEINTWKDLFLQKNVKLYNYGKEQPKILRKMGHINILHP
>NSE_0031 purM, phosphoribosylformylglycinamidine cyclo-ligase
MKKTLSYKSSGVNIDTANSFVDFIKKNAEVDKHCVSAIGGFASLFSVGNL
NYKDPVIAAATDGVGTKLLIANECNNHASIGIDLVAMCANDLICHGAKPL
FFLDYYSTGKLELDVARAVISGILVGCREASMSLVGGETAEMPGLYSAGE
YDLAGFAVGIVEKEEILPQNVTKGDILIGLKSSGFHANGFSLIRKTFSSL
SIKYSTLFDKRTWGEILLTPTKIYVNSFLSLKKFIKAAAHITGGGLLENL
RRVLPEDLKICIQPYEFPEIFKWLMLNGNIPQEEMLTTFNCGIGMVLVVA
EQNAEFVSETLGEEALIIGNLK
>NSE_0474 purN, phosphoribosylglycinamide formyltransferase
MRKKVAIFISGRGSNMKSLLEFSKNEGKKIFSVALVISNKPDAAGISIAH
TYGIDTRICTSEEEILTVLSYVKVDLICLAGFMKILSKDFISRVGCDIIN
IHPSLLPSFRGLNAQAEALAAGVKIAGCTVHYVTPEVDAGKIIVQGAVPV
LKNDTVKSLSERILKAEHKCFPIAVEKVLTDNVEEDFIILQG
>NSE_0510 pyrB, aspartate carbamoyltransferase
MRSLLSNKDITVDEIYEIFDLAAFYLKNGIKNDLLGKVVFSVFFESSTRT
ETSFSLAASKLGCLVEKVNVSTVALKKGEHLVDFFTSLNALSPDAFIIRY
SQSGVLHILEKYIDCCIINAGDGTNEHPTQGLIDAFTILLLKEKIEGLNI
LVCGDIIRSRVAHSTIPILQRLGATVAISGPLSFMPTIQVEEIVYYDNFP
AAAKSADVIIMLRTQTERMGQKVLAGATANFHLDENILKDLGTDVLIMHP
GPIHRNCEISNAVLDDSRSTVLTQVRNSQYVRAAVLNFLMKS
>NSE_0154 pyrC, dihydroorotase, multifunctional complex type
MKKWNLPTGSDRKVAFVDARIVDPESGLEILGDLVVHGRRIGDFGESLLS
DVELKSFDEVVNCDGHILMPGIIDIHVHLRDPGQLQNEDIHSGTKSAAAG
GVTTVVCQPNTDPPIDTVETLAYIRDKAKRVGFVNVLCYASITGRGGDLT
DMFALHKAGAVGFTDDGLPVMNSLFMRQAFMNAALLKVPVAQHAEDLDLS
NGGCINEGAISHKLNVPGISHLAESVMVARDVLLLEQLGAHYHVLHVSTK
KTVEIVRAAKDKGMRVTCEVTPHHLLLTEEAVDGYNTAAKMNPPLRTEED
RLCMIEALKDGTIDAIASDHAPHNEVYKELPLKEAAFGVVGLETILPLSL
ELYHSGALELHSLLAKLTCNPAKIIGSEAGRIKVGAPADLVLLDLNSEVR
IETRQFVSKSKNSPFGGRKTRGKVLRTIVGGDTVYMDV
>NSE_0179 pyrD, dihydroorotate dehydrogenase
MHEKLLVALLQRLNPSFAHDVTRVVLKHFPGFVSQNSFEDPILESRVCGL
HFKNPIGIAAGFDKNAECVTALRRVGFGFIELGTVTLKPQKGNPSPRLFR
LPQDGAIINRLGFNNKGIAYFLKSLKKAMTHMDLPPLGVNIGKNAVSSNA
VSDYARLAAYVSSVADYITLNISSPNTVSLRDMQKVEILEELLIAVKAAV
GSNVRIFIKVAPDLAEGAEVGIISLALKHKVAGIIVSNTTIGCRESLHSK
HKVEYGGLSGTPLFKLSTGLLRKMYRCTNGELVFIGCGGISDAETAYAKI
RNGAALIQAYTSFTYHGFGLLNQIKKDLVQRLKADGFSSVSEAVGVDA
>NSE_0538 pyrE, orotate phosphoribosyltransferase
MRVSRKGQVEEALLDELYASGAILKGHFVLSSGLHSDTYVQCALLLQNPR
RVFKFASALVQLIPEKIKSVVDLIVAPALGGLIIGYEVARLLDKDFVFFE
RFNGELTLRRGFKVESGQNVLLIEDVVTTAGSSIDVIQKVHDRGANVIFA
ASIIDRSEGAAEKRFKKHSCEFLSVVKLNCVTFDAANIPKELSNVPCIKP
GSNNLN
>NSE_0793 pyrF, orotidine 5'-phosphate decarboxylase
MKPKIICAVDNPDFGYSYSLVSSILEYVHVIKLGLEFFSSCGIAGIEKVA
ALGLPIFLDLKLHDIPNTVARTISVIKQIERVEFLTVHITGGMEMLAAAK
EALQGTKILLIGVSVLTSLVQKDLENNGIEIPLLEYVKKLSVFAKKCCLD
GVVCSNQEAPTVRDACGEEFIIVTPGIASKYSDDQKRVSQISALKNSVSD
YVVIGRAITRASDPVKATKEIISSLTRE
>NSE_0877 pyrG, CTP synthase
MNRRSCAFIFVTGGVSSSIGKGLTTSALASLMQSMGFRVCIRKMDPYLNV
DPGTMSPLQHGEVFVTEDGTEADLDLGHYERFTGINCTHRDSTTAGRIYV
DLIERERNGEYLGATVQVIPHVTNLIKDFIYSGSDQYDVILCEIGGTVGD
IEGQPFFESARQVAYEVGKENVIYIHLTLVPYLEASGELKTKPSQHSVKA
LNALGIQPDFLICRTQSAQMSAADKRKIALFCNIREGNVIEAQDVDNIYK
IPLIYKEQGLDTKISALLGCGPLEAGVSHWKEIVGRTRSLANSGKKLFVA
IIGKYSGLCDAYISVDSALQHAAFAVGVNLSVQIIDARGKDMSDLSKFDM
ILIPGGFGNNGIDGKLLAITHARINNIPFLGICFGFQLAILEFARNVVGI
KDADSTEFNKNCKAPVICFLDEWHRSDSSVERRRQSSQVGGTMRLGGYNC
VLKKESKAYAIYNETEVISERHRHRYEANPHYLPELEAKGMLFSGYSEKG
CDIPEILELKDHPWFLGVQFHPEFKSRIFKPHPLFLSFVRAGLLRKYS
>NSE_0946 pyrH, uridylate kinase
MRRVLLKISGERLAARGVSVHDAEVIGMLARGIKRVHEMGIQVCLVIGGG
NIYRGSSGIPNIDRATGDYMGMLATVINALALQGAINNLGVVSRVQSAIP
MRSICEPYVRQKAISHMEKNRIVIFAAGTGNPFFTTDTAAVLRSVEMGCD
VMLKGTLVDGIYSDDPRTNINAERITKLSYTDVLSKKLRVLDSSAVSIAR
DNGMPVVIFSLDSEMAFYEVINKQGNYSTIEGE
>NSE_0163 thyX, thymidylate synthase, flavin-dependent
MVDKENLNKTKRVVSESLEEKLGESYQVFNSGFVRVVDYMGNDQAIVQAA
RVSYGKGTKTVNQDRGLIHYLMRHGHTTPFEMCEIKFHVKMPIFVARQWI
RHRTANVNEYSARYSIVKEEFYIPEIDKVCYQSATNSQGRGDRLEQEFAQ
EFRHFLIESNSATYDEYTRFIETGLAREIARIAMPLNTYTEMYWKVDLHN
LFHFLKLRSHQGAQYEIRKYAEVIEEIVGSWVPMAYEAFLEYVKHAKTLS
RSAIKYVRDNLKGELSSEREKYGIGMREFTEVTEILSGTEEG
>NSE_0547 tmk, thymidylate kinase
MFIVLEGIDGSGKSTQVKLLSKFLAKDGYPCVLTREPGGTSFAESLRSMI
LHDPIDPMARLLLIVSARVDHYNKVILPALKEGKVVVCDRFIYSTLAYQG
YGDKIDLQTILDLHRLSGCLVEPDLTLLLLGSGHKKLGRDNFERMPREYL
SNVCMGYEKIARMYPNIHVIKCMGVGRTSEEIVKIVQGKISEKQTSSCR