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# Anaplasma phagocytophilum HZ, HZ

>APH_0248 hypothetical protein
MIPLAPWKSISVVYMSGSDEYKEIIKQCIGSVKEVFGEGRFDDVVASIMK
MQEKVLASSMQQDDTGTVGQIESGEGSGARLSDEQVQQLMNSIREEFKDD
LRAIKRRILKLERAVYGANTPKES
>APH_0160 putative thymidylate synthase, flavin-dependent, truncation
MVDEATEYTKRLVVPALENVLYQEHKVLDHGFVRVIDYMGDCGSLKVVPV
ML
>APH_0321 cytidine and deoxycytidylate deaminase family protein
MRASAYMKIAMEEANSSSGEIPVGALVVRNGVIIAKAHNLTIQNTDPTAH
AEIVAIRMACKALSTHILDGCDIYVTLEPCAMCTQAISLARIRRIYFGAC
NEKLGGIENGAQVLKYCLHVPEVYGGFLEQENAELLKAFFKKMRLKK
>APH_0104 uridylate kinase, truncation
MTLQATIAKQSHIQTPTESLYAYGSTDCNVVENVRYSRVLLKVSGEALAG
ERGFGFDQNVIGKLSCGLKNMRESGVKLCIVVGGGNIFRTKLKSSAH
>APH_0087 putative phosphoribosylglycinamide formyltransferase, truncation
MTFVVRRKPLDIEHISTVLREHDVGLVCLAGFMSILPEKFVTDWHHKIIN
IHPSLLPSFKGLNAQEQAYKAGVKIAGCTLHYVYQELDAGPIIMQAAVPV
LREDTAESLASRILAAEHVCYPKGVKLIAQDKIKLCDDGTVQCTGEDELF
LFQENF
>APH_0860 HIT family protein
MEPSLYDNDNVFAKILRGELPCTKVYEDDNVLAFHDIKPEAPVHVLVIPK
GKFVSFDDFVESGYDVSEFFKTVGKIARQFNLHTGGYRLVTNHGKSAGQI
VHHFHVHILGYPQREHDCTNNSGE
>APH_0225 putative phosphoribosylformylglycinamidine synthase I
MNVIVLSGYGLNCEEETLFAFQEAGRYLNTNISGKIVHIKELLSNPKQLA
SFNTMVIPGGFSYGDDTGAGNAYALRLIHGLNEHIRDFMARDTLLLGICN
GCQILLRMLCPNVALVSNDVGMYQCRWVTVKASNNSVWLDGIDKMYIPVA
HGEGKFYAAEDVLQNLETQGDIALRYVNSDGEYAEGEFPYNPNGSARDIA
AITCNSGRALMMMPHPERAIFFTQRYDWTDIVHGHQNTKGAVEKYADGFQ
IFVNAVRYFS
>APH_0211 phosphoribosylformylglycinamidine synthase domain protein
MHVSDSELMRISKDGIQNRGPLNLSLDALKAIRAYFEKHNRSPNDIELET
LAQTWSEHCKHNIFSPSIDEIAEGLYKHYIKRATTDINSPICVSTFPNVH
TIAA
>APH_0213 putative phosphoribosylformylglycinamidine synthase II
MIVSIVVDNILNPENKQVYTVSLPHEVNKELVVRIGQLLSNAVTDKFYAF
VYEDDVYAPGLPGYRNMASEAPYDMFEIFNAESSIETAYLPGMTDNVGDT
AAQIIRESLGIENVRVHASEISFYETCNPPAKNYNPLVKYCKLVTHNPSK
KLFNVQFFGNQHIEELNRVLANLNKTPHPIPYLRAIDIGGSAPYSHSVCS
VDLHVSDSELMRISKDGIQNRGPLNLSLDALKAIRAYFEKHNRSPNDIEL
ETLAQTWSEHCKHNIFSASIDEIASGLYKHYIKRATTDINSPICVSTFSD
NAGAIVFDDDFLVVDKVETHNSPSALDPFGGAETGILGVNRDIIGFGMGA
KPIMNAYYFCFAESLEQPLYRDKECKESVLAPTQIMDGVILGVNTGGNCS
GIPTAIGSMYFHNRFCGKPLVFVGSTGIIPRHIGEKPAHIKTVKNGDYIV
VIGGRVGRDGIHGATFSSHALKENVGCTVVQVGSPITQKKLSDAIVKEAR
DRGLYNAITDNGAGGLSSSVGEMGEKGFIVDLEKVPLKTDKIMPWEIWVS
ESQERMTLAVSPEQYPALEELMLKHDVEIRVIGEFNNTGKAVVRHNGTVI
MDIDTDFLHNGNPALTLHTEKWQPAYIHTTVTHDVSIEDDLLNMMGRKNI
CSREFLVSQYDHEVQGSSAIKPLQGKGRICGDAVVLRPVLSSTRGVVKAQ
GFGCVYAEIDPYNMAACAIDTAIRNHISVGGNIEHMALIDNFCWCDATNP
KRLWQLKQAAKACYDYATAFGTPFISGKDSMFNDFHGYDGSGTSIHISAL
PSLLVSTLGIIEDVSNAITQHVKGPSLIYVLGTTYNELGMSEYQLYSGMG
NENVPSVNAENAMLLYKRFHQASMRKVIASAIAPGLGGLATSLIKSLIGG
HMGAEIDLSAVITSDVPQNDMWAKTVLFSESQSRIIATVSVENQHEFESL
FADVPYALIGRVIPEYVLKISGITTISLELLERKYKEFSNSRYNGVRVDQ
L
>APH_0147 guanylate kinase, truncation
MREHVVSIFIMPPSMEELRRRLCGRRADDSEVVEARLKGAAFEISHCEAY
DYVIVNEDIEETADRISNILRAEQMKTCRQVGLRELLESRFPIED
>APH_0130 putative deoxycytidine triphosphate deaminase
MSVMPDHWIKERALKDGMISPFVDHKEGTGVLSYGLSSYGYDARLDNKFK
IFANTHSVVVDPKNFSQDSFVDREGDFCIIPPNSFMLAKTVEYFNIPRDV
MVVCVGKSTYARCGIVVNVTPLEPGWSGYVTLEFSNTSPLPVKVYAFEGA
CQFLFFSGKERCSKSYDEAGGKYMGQSDVTLPIIS
>APH_0300 adk, adenylate kinase
MEKEQVNLLIFGAPGSGKGTQARLLGEYLKGLEVISMGDLLRAEVASKTV
IGAEVEAIMQEGRLVGDPLVCEMIFRKLRGFSAGFLLDGFPRNLPQAEFL
TAVMQLLNRKIDAVLKLEVDAAVVENRLQGRLVCKGCGAVSNAVFNHGAC
QACGCEEYVRRNDDSLNVIRRRLMDYDREVTVLEGYYQDKVIRINGDRTV
EEIHGDVKHVLDRLNN
>APH_0381 carA, carbamoyl-phosphate synthase, small subunit
MTSEFHNAVIVLSDGRYFFGRSLGKRTDCVGEVCFTTGVTGYQYTITDPS
FAGQIVTFTFPHIGNVGINSKDFECEQVLAKGIVVREISGASHVSSHIDL
NSWIEQNNFTGISGVDTRALAIHLRENGTLGGVIHHFDDIGAVHIQELQN
VARTHKKSLATELPHLMDHSHHVDGHSVCVIDFGAKHGIFSALTRIGCAV
HVVAAQNDFAARALSLKPRGIVISNGPGDPADISDPVMDQLRVLIDSGIP
VLGICLGHQLIAKALGAKTIKMHHGHRGSNHPVYSLETKSVEVTSQNHGY
TVDASTLPDNIEVTHISLFDGTVEGIKMTNRPVLSVQYHPEGCPGPNDSH
YIFRKFADLITSAHA
>APH_0249 carB, carbamoyl-phosphate synthase, large subunit
MPKRTGIESILIIGAGPIVIGQACEFDYSGTQACKVLREEGYRTILVNSN
PATIMTDPDLADSTYIEPITANFIEQIIIKEKPDALLATVGGQTVLNVAL
ELFDKGVLSEHNVEMIGTNHTAIRKAEDRGLFREAVHKVGAKCPKSVIIR
QGDPIAPALEYIGLPAIIRPSFTLGGIGGGIATTEAEFYAAVERGFVMSP
TSEVQVDESIIGWKEFEMEVMRDCRDNCIVVCSIENIDPMGVHTGDSITV
APALTLRDEEYQKMRNISFDILREIGVETGGSNVQFAVNPQRDGEIVVIE
MNPRVSRSSALASKATGFPIAKIAAKLAVGYTLDEIVNDCAISIPASFEP
VMDYVVVKIPRFDFAKFRVPDQALSTSMKSVGEVMAIGRSLPEALQKALC
SLEVGYTGLNEVFDENTCIEHVYKELANPSPGRILMIADAIRMGVSSQKI
NEITCYDPWFIQQISRIIACESDIKQNGLPTTKEDLLYLKKMGFSDARLA
ELGNVSVDYVEDLRQKLSVNPVYKRIDTCAGEFRTNTAYMYGCYEGDSIN
TPECESHVTAKEKVIILGSGPNRVGQGIEFDYTCVHAAFTVKQLGLEAIM
INCNPETVSTDYDISDRLYFSPVSRECVLDIIRNESQGAASVKVIVQLGG
QTPLKLAKILKEKAVHVIGTDFESIDLAEDRMKFKGLLQSLGLKQPRSIT
CVTAEEVLRKVEEVGYPVLLRPSYVIGGQFMSVVRDRSALSSYLHINKNV
FDTGCLLIDEFLNDAVEVDVDAICDGDNVYIAGIMEHVEEAGIHSGDSAC
SLPYYTLGKEIVDLIAECTKKVASALNVRGLLNIQYAIKDKELYVLEVNP
RASRTVPFIAKASGVPVAKIATSVMLGNKLSIDQEINEMPYTAVKEAVFS
FSRFASADPLLGPEMKSTGEVMGIDETFGMAFLKSQAAAGYELPTSGKVF
ISVKNSDKPAAAVLAKKLIALGFEVLSTKGTNNYFNELNIPSTHVNKVRE
GSTHIVDMLNNNEISLVINTSEGIKTISDSADIRRTAMMKKIPHSTTLAA
AKATVISLEELAAGRTPKVIPVREYHEKNRHRRKAE
>APH_0274 cmkB, cytidylate monophosphate kinase
MGATSLEGNSVRRIVIAIDGPSSSGKGAMASAIAAELGFVHMDTGMLYRI
FAAEFAKNYIHSASAENYEICITAEDRCKMLSLLAENNSQYSSEAVGKAA
SIISRNGQVRAALLPIQQEFVRSSKRGVVLDGRDIATIVCPDADVKIFIT
AYASIRALRRYKQLRLRHGTRKVMYKNVFYSLLNRDIRDSCRSKGPLRRV
KEAYYLNNSHINKEISLHQLMKKIKTFL
>APH_0379 dut, deoxyuridine 5'-triphosphate nucleotidohydrolase
MKVGIIRMKGGEGLPLPSYATPQSAGLDLYAALSEEVVIRSGERCLIRTG
VAIELPDGYEAQVRSRSGLAVKAGVVVLNSPGTIDADYRGEIAVILANFG
ASDYVVKHGDRIAQLVIAPVMRISWEESSNITETQRGAGGFGSTGV
>APH_0170 gmk, guanylate kinase
MLKSVGVILVLSSPSGCGKTTVANKLLEKQKNNIVKSVSVTTRAARKGEK
EGKDYYFVDREEFLRLCSNGEIIEHAEVFGNFYGVPRKNLEDNVDKGVST
LLVIDWQGAFKFMEMMREHVVSIFIMPPSMEELRRRLCGRRADDSEVVEA
RLKGAAFEISHCEAYDYVIVNEDIEETADRISNILRAEQMKTCRQVGLRE
LLESRFPIED
>APH_1233 guaA, GMP synthase
MLTIAIIDFGSQVTQLIARRVRELGVYSEVFSVDTDFPALLAQGKKIAAF
ILSGGPNSVSELQNIPKVVSDVLEINLKTGTPIMGICYGFQLLAHSFSST
VESDKAREYGHAQLQIVGESAITKGIWSVGQTACVWMSHSDSVVDNVPQG
FNVVARSMNTQAIAFISNEERKIYGLQFHPEVSHTPEGRDILNSFLTTVG
CARNWTVSSFLNTQIDDIRRTVGNGVVVAAISGGVDSSVASVLLHRAIGD
QLKCVFVDTGLLRKGEVETVREFFVDKLKMSVSIVSAAFLFIERLRGVVD
PEEKRKIIGNTFIEVFEQEAKKLGDAQFLMQGTIYPDVIESGASGLGVKI
KSHHNVGGLPENMNLSLVEPLRCLFKDEVRALGSELGLPDVILKRHPFPG
PGLAVRIIGEVTEEKLQLLQEIDNIYISMLYESGLYHDIWQAFSVLIPAR
TVGVMGDSRTYGHVCCLRAVTSSDGMTADCFPFGEAKEKQLKFLEFLQKV
SVAIVGSLPRVNRVVYDVTSKPPATIEWE
>APH_1217 ndk, nucleoside diphosphate kinase
MQERTLSILKPDVVERGIIGNVISYIEAAGLKVVAQRMCRLTVSQAEEFY
DVHRDRPFFPELVKFMTSGPVVVQVLEGESAIAVYRDVMGATNPKEAAKG
TIRADFAESIDANCVHGSDNADNAKREIMFFFGECEIFKR
>APH_0331 nrdA, ribonucleoside-diphosphate reductase, alpha subunit
MVVGVYNVSQIVIDYTRDDNLTNFGKAVLSDRYLLEKEDYQQLFVRVAQY
YSDDSQHAQRLYDYMSKLWFMPATPILSNGGTSRGLPISCFLNETEDSLA
GILNLWNENVWLASRGGGIGSYWGNLRSIGERVRGSGKTSGIIPFIVVQN
ALTLAISQGSLRRGSSAVYLPVWHPEIEEFLDIRRPTGGDPNRKALNIHH
GVLLSDEFMEAVEHDKTWDLLSPKDKCVISTVKARDLWIKILTTRVETGE
PYIIFVDAVNRCKPEIYKKLGLDVKMSNLCTEITLTTGEDHLKKSRTAVC
CLSSLNLEYYDMWCGNPQFIEDVMRFLDNVLTDFVQKAPTELERARYSAM
RERSIGIGVMGFHSFLQSKMVPFESFAATMWNKKIFSYLKSQADAVSRKL
ALEKGACPDAQDANEMERFVHKLSVAPTASISIIAGNTSPGIEPYAANVF
THKTLTGSFIVRNKFLQELLKSKGKDDDQVWSSISTNEGSVQHLDFLTDH
EKLVFKTAYELDQRWVIEHSGDRTPYICQAQSVNIFLPAGVHKRYLHKVH
FLAWKKGLKSLYYMRSKSVQRADKVSHEVNGAAAVVPRKQLTNFSYDECL
SCQ
>APH_0560 nrdB, ribonucleoside-diphosphate reductase, beta subunit
MSLLDAKPVYKPFDYPWAYDAWLCQQRIHWLPEEVPLADDVQDWKTMLSE
KEKNLLVQIFRFFTQADIEVNNCYMKHYSNIFRPTEICMMLSAFSNMETI
HVAAYSYLLDTIGMPEVEYQAFLKFEVMKKKYDYMQRFEECRRGDKRHVA
KTLAVFGAFTEGLQLFASFAILLNFQRFGKMKGMGQIIAWSARDESLHTD
SIIRLFNTFVHENGEIWDDDLKQELYDACKVIVMLEDEFIDLAFALGDVE
GLSACEVKRYIRFIANRRLKQLHLEPIYDVAENPLPWLDEILNGVEHTNF
FENRVTEYARAATEGTWEEAFED
>APH_1112 prsA, ribose-phosphate pyrophosphokinase
MVIIPGSTSLALAKSVSGMLDVPMVIPCVSRFADGEINLEVPTGVATGSG
HIVLMQSLSAPASDNLIELTLLTDAVRRTLAPQRITAVIPYLCYSRQDRV
MQRVDSQETFTSALSAKVIARILSTSGLDHIVTLDLHSQQAAGFFDVPFT
NISAYDVFVDYLSSSNLLERLVIVSPDYGALGRVRAFVRMLSSRYNMNSI
QVAVIDKYREGPGISEVMHVVGNVQDRHCFILDDIVDSGGTLCNAAAALK
TRGAISVHSFITHGVLSGRAIDAIGTAELDSLVITDTIHNPDRVNLPEKI
KVLSVDRLLSDYLLSHAVWRKS
>APH_0336 purA, adenylosuccinate synthetase
MPSIVVVGLQWGDEGKGKIVDWLSENADTVVRFQGGSNAGHTIVIEGKVY
KLSLLPSSVLRPGKQSIIGNGVVLDPYALVREIEKLQESNIELTPENLSL
SETCPLVLSVHRETEVILENLRGVHAIGTTCMGIGPCYEDKIGRRAIRLC
DLLDEKSLREKVEFLLSYHNLLRKATNKDELQSEKVMEEILFIAPKVLPF
MKHVGGMIYEQLAEGKTVLFEGAQGALLDIDHGTYPYVTSSNTLAGCVPI
GCGVGSPGSIRVLGLAKAYTTRVGNGPFITELTGDLDDLMVERGREFGTV
SKRRRRCGWFDAALVRHAALLSGATELALTKLDVLDTLSEIKICVGYKHG
ESFYNYLPPASHIQGALEPIYEVLPGWQSSTLGAVSKNDLPANALAYVQR
IEELVQIPVSLVSTSPDRDHIVFLGDSSSIAKSY
>APH_0867 purB, adenylosuccinate lyase
MIARYSIPEMVEIWEEENKYRIWFAIEKSACEAQVKLGVVPVHVLDSLKL
VDDRKFDIKRICEIEAEVKHDVIAFLSYIAESTSTDIRYLHYGMTSSDVL
DTCLSFQLKQSCDILLKNIEDVLGILKRRSEETKYLLCMGRSHGVHAEPI
TFGLKLARFYAEFERNRQRLIRAREEISVCKISGAMGNFAHLDPYVEEYV
GNSLGLKPETISSQVISRDRYAVFFATLGVIASSMEKIATEIRHLQQTEV
LEVTEPFSQGQKGSSAMPHKQNPILGENLTGLSRMIRSYVVPAMENVALW
HERDISHSSVERFIAPDACVTLNFALVRLAHLLQNMCINEERIRANLDSS
KNMMLSQRVLLALVDTGMSREQGYKIVQDCAMDSWKNGTDFVENISNHPQ
ARDCLKDIGELADLSYYTKHVDFIFNKVFGTE
>APH_0119 purC, phosphoribosylaminoimidazole-succinocarboxamidesynthase
MENTREVLYEGKAKIILRHPENERAVIQHFKDTLTAFNAQRKSEIQGKGA
LTNRISSLLMEHLEASGIRTHFLSFLNDKEQLVSKLNMIPLEVVVRNIAA
GSMCKKFGIPKGKVLAEPIVEFYYKNDELSDPMIAEDHATCFGLASKSEL
ARMREIALQANNILSALFSEVKILLVDFKLEFGKDSHSEQEIVLGDEISP
DTCRLWDTSTLTVLDKDLYRFDIGNIEDGYKEVLQRLEQHFKNK
>APH_1088 purD, phosphoribosylamine--glycine ligase
MNVLVIGSGGREHALLSCLSRSPMLERLFVAPGREAMSDLATLVDVNVDN
FVEVVQLCKQEKIDLIVVGPEQPLINGLADALSDEGIFVFGPSKAASRLE
ASKGFTKELCSRYHIPTARYGYFMDINAAKQYVKRSKLPLVVKADGPAKG
KGVVVCRTHDEAYDALESMLVHGKFGKAGDAVVIEEFLEGKELSFLTLID
GTNPVVLGAVQDYKTLYDGNKGPNTGGMGSYSSPNIMTPEMEHLIVQKIV
YPTIKAMYNMGIRYRGLLFAGIMIRKNEPYLLEYNVRFGDPETQAILPRL
DSDLLRLMSLTAKGRLGSEVVELNRKSVVCVVAASKGYPDKCETGSVING
LDAVAKCPNVQVFHAGTKRVGNAWVADGGRVLNVVASADDLDAAKHQVYA
ALDLLDWPGGMYRYDIGS
>APH_1279 purE, phosphoribosylaminoimidazole carboxylase, catalytic subunit
MNEPKLPPVPVAVIMGSKSDLPTMSAAISVLDELMIAHEALVVSAHRTPE
RLFNFAKSAHETGFKVIIAGAGGAAHLPGMVAALTHIPVIGVPVMSECLK
GMDSLLSIVQMPKGTPVATMAIGPAGAFNAAVLAASIIGLWDENVSLRLQ
NWKQKITDSVSITPY
>APH_1300 purF, amidophosphoribosyltransferase
MPFASIYEECGIFAVQNHSNAVHKCLLGLHALQHRGQESFGIAASTPGIS
ELVSFYSGGCVSNIFSNPEVHTLTGRMAIGHVRYSTSGGLTASGAQPFIV
QGRFGPLAVAHNGNLTNARSLREELIDKGCQFTSEIDTEVVAHLAVVDEA
ETFVDCVINALKRTKGAYSFVIMVRDTLIGARDPAGIRPLVLGMVEGSYV
LASETCALDIVGATFVRDIKPGELVVIDKSNNITSLFPFKPLKYSFCIFE
YVYFARPDSVVESKPVYETRKNIGAMLATESPPPSDVDMVVPVPDSGIPA
AMGYATKSGVPFEFGIVRNRYVGRTFIQPTDKARKLGVELKHNANSAILK
GKSIVLVDDSIVRGTTLREVIVLLRKAGTKNIHLRISSPPTVYSCFYGID
TPHRSSLVANNMSIADLVKMLDCDSLSFISIDGLYKAIRGAKRDSDNPQY
CDACFTGYYPVGEMECNS
>APH_1207 purH, phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
MQKTKVALLSVTDKEGVEELARFLVKNGFRILATKNTNLLLRDSGIESTE
VSEYTEYDEIMGGRVKTLHPKIFAGILCNRGSHMQEGERLGIDNIDLLVV
NLYPFAQCVARADATEHDIIENIDIGGVALLRAGAKNFQHVTVVLSAQDY
DELKGEIENNGGNTSLEYRKKMAARAFALTAAYDARVHSWLLCDKQDEVL
PSEIVIHGKKVQDLRIGENPHQKAALYCVGSYGDALPIEQIHGKDLSYNN
IVDIESAIKIVADFDVPAVSVIKHGNPCGVAISSEGIDDAYEKAISCDPR
SSFGGIIALNKAMTMDIARKVMSIFIEAVVAPDFDDGVIDTLTAKKNMRI
MRYKPYTPDRLVVKSTLSGGLLVQECDRSVVNISDFKLATEVSASPEVLN
DLLFAWRVCKYVRSNAIVIARDGRAIGVGAGQMSRVDSVEIAIRKAGNCA
GAVLASDAFFPFADSIQHAVSAGIAAIVQPGGSLRDQEVIDAANASGIPM
YFTGVRGFCH
>APH_1119 purK, phosphoribosylaminoimidazole carboxylase, ATPase subunit
MRTSVSHNMLSATRVGIIGGGQLGKMLSLSSSKLGYQTSIFAESAIDPAV
FVTNSSVIGSFSDTEKLRTFASMVDVAVIEFENIPVSAVHTLQETIPVYP
GVKALHVAQNRIREKTHIQSLGIAVADFAVIHSHTDLHKAVQDVGVPSVL
KTAESGYDGKGQYVLRSTEDVGSLAHLPLEQGYILERLIEIEKEISIIIA
VDRNASHTFFPVAKNTHVDGVLSESIVPAGISTDLQKQAQEIAYAIATSL
EMVGILAVEFFISKSGKLLVNEIAPRPHNSGHWSQDACNVSQFEQLIRIA
CWLPMRVVHLLTPCVMRNVFGDNIIDEEIHQDHRNSISLYGKQPRAKRKM
GHINSLLY
>APH_0202 purM-1, phosphoribosylformylglycinamidine cyclo-ligase
MSKYLDSGVDIASADKLVGEIKQLSQETKSDNVVSEIGGFGAVFDLYATG
HKYRSPLLVSSTDGVGTKLLIAQATVQHQHIGVDLVAMCVNDVLAQGAKP
LFFLDYFATGALDPSVALEVLRGISHGCKLAGASLVGGETAEMPGMYSRG
HYDLAGFTVGIVEREDILPKLDLIQAGDVILGLPSSGLHSNGFSLVRKIL
KDLDIDYSSPCPFSEKELTWADVLLEPTRIYVNSVLPTCHLLKAIAHITG
GGLVHNVPRILPTHLAAEIRQDSWPKQNIFTWLEGAGNIPKEDMLETFNC
GIGLVLVTARETSAELMAMLAELGETAYVIGAVIPRGEKPVVLR
>APH_0210 purM-2, phosphoribosylformylglycinamidine cyclo-ligase
MSKYLDSGVDIASADKLVGEIKQLSQETKSDNVVSEIGGFGAVFDLYATG
HKYRSPLLVSSTDGVGTKLLIAQATVQHQHIGVDLVAMCVNDVLAQGAKP
LFFLDYFATGALDPSVALEVLRGISHGCKLAGASLVGGETAEMPGMYSRG
HYDLAGFTVGIVEREDILPKLDLIQAGDVILGLPSSGLHSNGFSLVRKIL
KDLDIDYSSPCPFSEKELTWADVLLEPTRIYVNSVLPTCHLLKAIAHITG
GGLVHNVPRILPTHLAAEIRQDSWPKQNIFTWLEGAGNIPKEDMLETFNC
GIGLVLVTARETSAELMAMLAELGETAYVIGAVIPRGEKPVVLR
>APH_0230 purN, phosphoribosylglycinamide formyltransferase
MKKELRVGVLISGRGSNLEALAKAFSTEESSVVISCVISNNAEARGLLIA
QSYGIPTFVVKRKPLDIEHISTVLREHDVDLVCLAGFMSILPEKFVTDWH
HKIINIHPSLLPSFKGLNAQEQAYKAGVKIAGCTLHYVYQELDAGPIIMQ
AAVPVLREDTAESLASRILAAEHVCYPKGVKLIAQDKIKLCDDGTVQCTG
EDELFLFQENF
>APH_0503 pyrB, aspartate carbamoyltransferase
MKKLNKLLRIQSLSDVDIENIVALAHRYLQDSSANNVLQGRVIANLFFEN
STRTLLAFEIAEKSLGAVSVTLNVETSSMKKGESVSDTLSTLSAMGVDLV
VVRSGFSGFIDEVVERVGDCCVINAGDGNHEHPTQALTDYATIRYLKGKY
IEGLNVTICGDIFHSRVARSNMRLLSRYGANINVVTPPCWSASVPSSNVT
KITHSLEEGIKDADVIMLLRIQKERMSGASFISANEYSRHYMLDNAKLSI
AKDDVIIMHPGPMNRGIEISDEVADASSSILLQVKMGVAVRKAILHYMLG
>APH_0245 pyrC, dihydroorotase, multifunctional complex type
MVSERQTWSLLQGGQCNEYTVAYINARIIDPASGTDYKGYLLTRGKEILD
FGPGFFDPNGAAFAASEVVDCNGHVLMPGIVDLHVHLREPGGEHKETVDT
GSRAAAAGGVTTVVCQPNTIPRLENVLVAKYLKMRALESSCVNIEFYGAV
TKSDGELCDMASLKDAGALGFTDDGLPVMNALYMKRAFEYAQDLDVVVAQ
HAEDCNLSDGGCINEGLVSRELGLKGIPDISESIMVSRDIQLLREVPGAH
YHVLHISTKKALDIVRAAKREGLRVTCEVTPHHFLLNESAVLEHGTMAKM
NPPLRTEEDRLSMISGLEDGTIDCIATDHAPHAAQEKTRPISCCAFGIVG
LETLLPLSLELYHNAGMSLMDVLSKLTSKPAEIVRLPRGKIAKGLVADLV
IFDLEHVWTIDTAKFSSKSKNSPFQGRKVKGKVLRTVVSGKTVYRAE
>APH_1013 pyrD, dihydroorotate dehydrogenase
MSLFRFNNPLFLIPPKVAHSLTLFALQQGLYSSSVRKMPECLSAQPLNFK
VRTPIGLAAGFDKNAEVIRPVLSLGFGFTEVGTVTKYPQSGNKGPRLFRM
HKQKAVINRLGFNNKGLTRLLKKVDSKDLNNLVFGINVGMYKGCSDPPAE
YAELVQKVYGLSSYITINLSSPNTAGLRELQKRNSLNEILASVRKARYAV
DHAESVPILLKIDPDLSDEVLQDVVDEVLRHKINGIIVSNTTTNFKLLGT
KAPISRGGLSGQPLFSLSTRVLADVYSQTRGRVVLVGCGGVSSGAQALEK
IRAGASLVQLYTAIVYGGFGIIDKINMELADLLTRDGFNKVEQAVGIDVH
>APH_1173 pyrE, orotate phosphoribosyltransferase
MRVSETCINSENDVLNILMERSAILKGHFLLTSGLHTDTYIQCAKLHEVP
SVCVLLCEALLKKARASGHEDLLNVDVVASPAIGGLMFGYEIARQLGVNF
VFFERVDGCFTLRRGFNVAENAKVLIVEDVITTGKSSLAVINAVTALGGK
VAGELSIVTRAKDVDMPVPVVSLLSLDIKNYREEEVPDFLAQIPISKPGS
SFIK
>APH_0527 pyrF, orotidine 5'-phosphate decarboxylase
MHQKNPIICALDTADLERATTLAKAISGKVAMAKVGLEFFTAHGLSGVQK
IVDLGFRIFLDLKLHDIPNTVRGALKSVVNLPAIDMLTIHVSGGKNMIMG
AIDALKECDIEPVGVTVLTSMDDVDLRACGINSSVEAHVMNLVDLAVSSG
LNAIVCSAKEVASIRKKYPSLKLVVPGIRMAQSATGDQKRVDTPKDTLAA
GADYLVIGRVITQSSDPAGEIDKILKTL
>APH_0038 pyrG, CTP synthase
MVGKLNPTRFIFVTGGVVSSLGKGLAAASIGALLQARGFSVRLRKLDPYL
NVDPGTMSPAQHGEVFVTSDGGETDLDLGHYERFTGVMKTRADNVTAGKI
YHELIVKERRGDYLGQTVQVIPHVIDLIISCILHNDAGADFVICEIGGTV
GDIESQPFLEAIRQVSYRLSKNLTIFVHLTLVPYIGAVGELKTKPTQHSV
KELSSLGIQPDIVLYRSRAQLPQYQCAKIANFCNVAEDNIIAALDVSNIY
MLPVMYHEHRLDTQILKHFDVDSPEPDLTQWENVLRMSETASDRIVIAIV
GKYVTSLDAYTSLEEALRHAGLHSGIRVEIKWVDARLPASEIDLTDADAI
LIPGGFGDNGIGTKICAIEYARVNNIPMLGICLGMQLAVIEFALNVAGIE
DANSTEFKSDCKNPVVCELPGLQVGDEYKMGGSMRLGSYTCNLAPGSRIM
SIYDSSTVVERRRHRYGINPEYRDVLSKCGLAFTGAAEDRDLPEVLELPD
HPWFIGVQFHPEFQSTPFKSHPLFLSFVTSTLQVKKASSRS
>APH_0111 pyrH, uridylate kinase
MSIDCNVVENVRYSRVLLKVSGEALAGERGFGFDQDVIGKLSCDLKKVRE
SGVELCIVVGGGNIFRGSSTSFGFERASNDYVGMLATMINALALQNSLED
MGIASRVLSAIPMTAVCETYIRRRAIRHLEKGRVVICAAGIGSPFFTTDT
AAVLRSIEMRCDAIFKGTQVDGVYSSDPKKDCSATRYDKISYHDLLASDL
KIMDAAAVSLARENSIPIIVFDLGKENAFSEVMKGRGTFTTISG
>APH_0163 thyX, thymidylate synthase, flavin-dependent
MVDEATEYTKRLVVPALENVLYQEHKVLDHGFVRVIDYMGSDASIVQAAR
VSYGKGTKQVSQDAALIGYLMRHAHTSPFEMCEIKFHIKLPIFVARQWVR
HRTASINESSARYSVVENEFYIPEACDVAEQSSNNAQGRGNPLTSEVAQN
VIGMFKDNSDSMYASYESMLSDGVARELARMTLPLNCYTHWYWKVDLHNL
LRFVTLRLGSGAQYELRAYAGKILDIIALWVPMVYAAYMEYCFESKTLSK
SALSVIRMLLKGEKVSREDVGMSKREWGELMATLYPDE
>APH_0093 tmk, thymidylate kinase
MFITFEGIDGCGKTTQSILLAKYMSDLYGEDNVVLTREPGGTSFNELLRS
VFLSVSDYKVDKLTELFLFLAMRRESFVKVVESALRANKIVISDRCVDST
VAYQGYGCGIDLDLIYKLNSLVMGIVPDMTFIIDIDIEKALSRATRNGYE
SNSMDFYHKVRKGFQRIAEEEKHRCVLLRCDDYEENGICDVYSVHNKIVG
LLQGVLHNKMDAASSSVKV