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# Thiomicrospira denitrificans ATCC 33889, ATCC 33889

>Tmden_1239 Ribonucleoside-triphosphate reductase, anaerobic
MVENILKRDGTHKEFLSFKIEDAIKKAFKSQNIIYDSSIFFNVLDELKNK
RVIAVEDIQDLIEKELYKSRYFDVMRSFMIYRHTHKMQRDSLLSEDTTYI
NSTQTIEEYILGTDWRIKANSNTGYSNAGLVNNTAGKVIANYWLDKIYSK
EEGYAHRNGDYHIHDLDCLTGYCAGWSLRVLLDEGFNGVRGRVESDAPRH
FREALGQMANFLGILQSEWAGAQAFSSFDTYLAPYVFKDKLPYNEVKKAI
RSFIYNLNVPARWGQSPFTNITIDWTVPSDLQDQIPTSKQLHLFKGMLDS
ELEEMALQRGVKSLQEMTYKNFQPEMNQINRAYYEIMTEGDLTGQPFTFP
IPTVNITEDFDWYGENTDVLFENTAKIGSSYFQNFIGSQYKRDVNGDLVP
NEEAYKPGHVRSMCCRLQLDLRELLKRGGGLFGSAEMTGSIGVVTINMAR
LGFLYKGSKEALYTRLDQLMEHAKSTLEKKRVFIQEMYDRGLYPYTKRYL
PGFRNHFSTIGVNGINEMIRNFTSDAYDISDKRGEDFAIEILEYIRARMV
EFQEETGNLYNLEATPAEGTTYRFAKEDKKRYGDSILQAGMGDNIYYTNS
SQIPVDLTNDPFEALTLQDDLQCKYTGGTVLHLYMQEKISSTEACRKLVK
NVISNFRLPYITVTPLFSVCPKHGYIAGEHEYCPKCDEELLSDVTIAS
>Tmden_1871 Amidophosphoribosyl transferase
MLEDMNEKCAVVGIYGNKEASKLAYFSLHALQHRGQEAAGISSSNGVKLQ
TIKKRGLVMRVFDEKKLETLRGSSAIGHTRYSTAGDDSILDAQPVFARYD
LGEMAIVHNGNLTNAEEIRNRLIDKGAIFQTFMDTENLIHLIAKSEKRKL
LDRIIDAVGKIEGAFSLVFLSRTKMFAMRDRHGFRPLSLGKLPGGGYIVA
SETCAFDLVGAEFIRDVKPGELLIFDEDKEPESIQVFEPTPKHCIFEYVY
FSRPDSKVFGQSVYQTRKDMGRELAHIKPVEADMVIPVPDGGVPAAIGYA
QESGIPYEMGIMRNHYIGRTFIEPTQEMRDLKVKMKLSPMTDIIKGKRVI
VVDDSIVRGTTSKRIVRMLKEAGASEVHMRVSSPPTTDPCFYGVDTPNKD
KLIAANMSQDDICKFIEADSLAYLDEASLLRSVKTDTDNYCTACFTGKYI
V
>Tmden_1118 Adenine phosphoribosyl transferase
MTLSNTERAIIESAIRDIKDFPKPGIVFKDITTLLNNGKAFGVTMNHLYE
KYKEYNLDYIAGIDARGFIFGAALAQMLGVGFVPIRKKGKLPYTTISEKY
SLEYGFDEVEIHLDAFSAIPNARVLLVDDLIATGGTAAASVKLINQAGAL
CVEACFILCLSFLDGYKKLQELTEVYSLVEVK
>Tmden_0122 hypothetical protein
MARDQTIFSEICIALSIIDARDTDFSFIENVTKKDEEIYLKELEKRSLLK
NGALSIEALKQSGLIIRNYLVGCGFTPKKIIWTGKDNIAGVVSVAKDLEI
LNFRISVKENADVFINGSPLTVFEDLPKGLFGQKKRGEDWFIKTAKDEIE
RYYALCRKHLSVHDDFSAIDKFYGNRDKAYKKEFSKKVALLHSEKNNEIL
ESYQIMCNKVSQISSEIFNQNLLKFKTAYTSSVSLQPIFHYFFKINGIKY
IIAGTEKNKPFASLLENSTSWTKQYSFLDIIASPKEAGQPEVLLRFIFKD
KKTNEQFEIPLKIEIRWSHGKFCGNPEAKVYKQWSYMELPWSENL
>Tmden_0422 Glutamine amidotransferase class-I
MTNVSIIVLDFGSQYTQLIARRLREDKIYCEILPYHTKVADIKAKNPQGI
ILSGGPSSVYNKDAYEVDQGVYKMDIPVLGICYGMQRIAADFGGSVVRAS
HHEYGKAELKILNLETNPSPLFKDCDDERIVWMSHSDKVDTLPAGFEPIA
VSSNSPYAAIANEEKRIYAMQYHPEVQHSEEGYLMLRNFARNICGVTEKW
KMEHFLKEQIKNIRAKVGSGKVLCGLSGGVDSSVVAAMLYEAIGDQLVPV
FVDNGLLRKGEREQVEEVFKINLKVPLVVVDARENFLSKLAGVSDPEKKR
KIIGHTFIEEFEKEAKKHDGIKFLAQGTLYPDVIESISVNGPSEVIKSHH
NVGGLPDWMDFELIEPLRELFKDEVRKIGLELGLPESMINRHPFPGPGLA
IRIMGDVNEADLTLLREADVILLDELKASGYYAKTWQAFVVLLNVKSVGV
MGDNRTYDNTVCVRVVEAVDGMTATFAHLPHDLLERISRRIINEVDGINR
VVYDISSKPPATIEWE
>Tmden_0547 Phosphoribosylformylglycinamidine synthase II
MSQQLQEIEKVLSSHKLSGDDYAHIKQILGREPNLVEIGIFSAMWSEHCS
YKSSKVHLSGFPTKAPWVIQGPGENAGVIDIGGGYAAVFKMESHNHPSFI
EPYQGAATGVGGIMRDVFTMGARPIANLNALRFGDVLKDNKTSAHQRYLV
RGVVAGIGGYGNCMGVPTIGGETSFDECYNGNILVNAFTLGLAKSDEIFY
GRADGIGNPVIYVGAKTGRDGLGGAVMSSDSFTEESKSLRPTVQVGDPFT
EKLLLEACLELFKTDHVVGIQDMGAAGLTSSSFEMAGRSGSGMIMHLDRV
PAREEGMTPYDFMLSESQERMLLCAKKGSEAEIIKIFEKWDLDAAVIGEV
TATGNMELFWHGDKVAEVPVNPVSEEAPVLNRPMSRPAYLDKIASVTIDD
FARVPNQEAFERLTKSMEVVDKSWIYTQYDSMVQTNTIKKGGMLDASVVR
VKENGKALAMSADCNVRYCYIDPKGGAAAAVIESGRNVAMSGARPLAITD
CLNFGNPENPEVMWQFGQSCLGIKEACSALTTPVIGGNVSLYNETNGVSV
FPTPSIATVGVNDDQNKVLMSSFQGEGNTLYLVGESNSEFGGSLYMKEIC
GVVAGVLPEIDYEKELTLWDLVIEANKKGILECAKDASSGGVAIALAKMA
AVSGLGCSARMLVNDERDIFAESMSRAIIEVKQENSASFESMAGVLQCQK
LGTVGGDIVKINNVSMSMKELQDNYFNTFKRVIERDI
>Tmden_2096 Ribonucleoside-diphosphate reductase
MVTIIKRNGRTEKLDISKIQKYTSAAVEGLSNVSQSELEVDAQIHFRDGI
TSKEIQQTLIKTAVDKIDIDAPNWTFVASRLFLFNLYHEVNGFTGYCSLE
NYFERGEKEGRLLYGLKGMYNLEELEKHIKPERDMLFNYLGVKTLYDRYL
IKDKNSNPIELPQHMFMAIAMFLAQREEKKEEWAIKFYNMISTFEVMLAT
PTLSNARTTRHQLSSCYIGSTPDNIEGIFDSYAEMAMLSKFGGGIGWDWT
NVRSMGSYIDGHKNAAGGTVPFLKITNDIAVAVDQLGTRKGAIAVYMEPW
HIDINDFLDLKKNSGEERRRAHDLFPALWLNDLFMQRVEEDAIWTLFDPY
DCRELTTLHGEEFNKKYVELEKNEAIIKEKLKAKNLWKKILTSYFETGSP
FLCFKDNANRANPNSHSGIIRSSNLCTEIFQNTNPNHYKIKFIFQNGDSV
SYEEEEIIEVDSGLKKPAKKVTALDSIGGREIYVVEKEKINGDTAVCNLA
SVNLSRINTKEDIDRVVPIAIRALDNVIDLNFYPIEKVKRTNMKTRAIGL
GVMGEAQMLAQEGISWGTQEHFDKIDEIMESVSFNAISASSDIALEKGSY
SEYEGSKWSRGIMPMDHATAEVKNLVDRGGLFASAYEWEELRTKVKNQGI
RNGYLMAIAPTSSISILTGTTQAIEPVFKRKWYEENLSGLIPVVVPELSP
ETWAYYTPAYDLNQTLLIKAAAIRQKWLDQGQSLNIFITLDKASGKYLNE
IYMLAWKLGLKSTYYLRSQSPEMASDVEDRSMECVGCQ
>Tmden_0490 Phosphoribosylformylglycinamidine synthetase PurS
MKVVVNVFLKAGVLDSQGKAVHHALKSIHFENVSDVRVGKQIVLKLNESD
EKKAMEDVTRMCEDLLANTVIEDYTIEIVK
>Tmden_0624 Dihydroorotase homodimeric type
MKTHTLLMPLDMHLHLRDGVMLENIAPLSAYSFSGALIMPNLVPPVETLE
DVKAYKERIMATVPNDFFEPYMTLFYKNYDKKFLATIVDHVTAIKLYPAG
ITTNSEGGLSSFNIEEMRETLEAMSILGIPLCVHGESDGFVMDREEEFMS
IYELLATNFPDLKIVMEHITTKAAVDMLDKHKNLYATITVHHLLFTLDDV
VGGMMMPHNFCKPIAKRPEDLDALLSVALEAHPKVMFGSDSAPHSKEKKE
CSGCAAGVFSAPIALQLLCEIFEQYDKLDNLQAFISDNAQSIYKICPEFK
EVILEKRPFIVPASYSNVVPMYASRAINWAIRSVE
>Tmden_1863 Phosphoribosylaminoimidazole carboxylase
MKFVSIVIGSRSDYEIMKSCSDTLEAFGVSYEMIISSAHRSPERTKDYIV
QAEKKGAHVFIAAAGMAAHLAGVLSSKTVKPIIGVPMSASALSGIDALLS
TVQMPAGMPVATVAIGKAGAINSAYLAMQILALDNEELAVKLKEDRIAKA
KKVEMDSMEIETILP
>Tmden_1098 Formyltetrahydrofolate deformylase
MSQYRVLIDANDEKGLVHKVSTVFYQNSFNILTNSEFVDSENNKFFMRSV
VEGDMPLDELYQSIVSVMPPSANIDVIAPKNKNIVIMATKEMHALGDILV
RHEAGELEANILCVISNYAELGSFVEKFNIPFIEISHVGLDRQEHEEKII
DTLAKFDNIDYIVLAKYMRILTPKFVEIYENRVINIHHSFLPAFIGANPY
KQAYERGVKIIGATSHFVNNNLDEGPIIAQEVIHVNHANGWRDMQRMGKD
VEKIVLSRALRLALEDRIFVYANKTVIF
>Tmden_1635 Cytosine deaminase
MDKFLQAAIEEAKKGLKEGGIPIGSVLVIDGKIVGRGHNRRVQDSSAILH
AEMDCLENAGRMAASEYKKAILYSTLSPCSMCSGAALLYKIPKIIIGENR
TFKGPEEYVRSCGVEVEILDNQECFDMMQSFIQKNPQLWNEDIGE
>Tmden_1224 Dihydroorotate dehydrogenase 2
MINYQSIKPWLFKLEPEDAHMLAEAALRIPNVCQVAFNPFLESHFITNSI
LKQELFGRTFFNPIGLGAGFDKNATMIRAMQILGFGFTEIGTITPKAQAG
NPKPRMFRHIEEQSIQNAMGFNNEGLLSAQKRLKKRFPFTTPIGINIGKN
KLTPDTQAINDYTTLIKALHELGDYLVINISSPNTPGLRDLQNEEFITKL
FEESKAITSKPILLKIAPDMSKEDAVALTKLAVLKGADGIIATNTTVDYS
LVKEPKSIGGLSGAVLKEKSFEIFEAVAKELYGKTTLISVGGISSAKEVY
RRIKAGASLVQIYSGLIYEGPDLIKNINNELTELIKADGYTNITQAIGAD
RK
>Tmden_0686 Amidohydrolase
MQIITPEYILTPQNLLRNFSVAFDKTIHKIAPLEELKILFPDAKIIKLQK
NSLLMPGLINAHVHVEFSANKTELSYGDFIPWLYSVLENRETLIEGCKKG
CMREAISCMLESGITTFGAISSHGMDLDVCADAKQNVVFFNELIGSQATM
ADALFADFLARLDASKSVNREGFYPAIAIHSPYSVHPILIKKALQIVKNE
NLKLTAHFMESSAEREWLDKSEGDFKEFFEKLLKQNSATCGASEFLEHFN
EQQTLFTHVVKANEEELLSIKKGNHTIIHCPISNRLLGNGALDLNEINKK
NINWICATDGLSSNYKLDLFEEMKCALFMHSNMPLLPLAKQLISSVTKDA
ALALGINSGEIEEGKNADMLVLDLDKEPNDELAIHLILHRYNISQIYING
KLIPKKGA
>Tmden_0550 Phosphoribosylaminoimidazolecarboxamideformyltransferase
MKRALVSVSDKSGVVDFCKSLVKNGFEIISTGGTYKILVENGIKAIEIDE
VTKFPECFEGRVKTLNPFVHGGILHRRDKQSHLDQAKELGVEAIDLVCVN
LYPFKATIEKTDDFEEIIENIDIGGPAMVRSAAKNFDGVMIVTDADDYVK
VIDAIENEKNTLEFRRNLMIKAYEHTAAYDSMIANYMNTRFNGGFGEKQF
IVGNKVMDTRYGENPHQKGALYEFDKHYSDNFKTLKGEASFNNLNDLSGA
VKIASAFGAENAVCITKHGNPCGFAIKDTLLEAYEEALKCDPVSAFGGVV
AVNGVVNKELALKMNEIFLEVIIAGRITQEAQEVFASKKRIKLFEMGSEK
LLLANDAKDFKHIDGGFVYQDADKVNNDEVKNAKLMTTRDATSQEKKDME
IAYKVASLTKSNCVVYVKNSAMVAVGMGMTSRVDASECALKKAKAMGLDV
TGAALASEAFFPFRDSIDAAAAAGVKSVIEPGGSIRDEEIIEAANEFGMS
LYFSEVRHFLH
>Tmden_1203 Histidine triad (HIT) protein
MKDILYAPWRDEYINDKEIKGCVFCHISQHAGEDEELHVLYRDESCFIVM
NRYPYTPGHFMIIPHLHTDKLELLPSEAWLHVSDLAQKCVRLLKEGFGAD
GVNIGMNLGIAGGAGIAEHIHMHLVPRWSRDTNFMTSIAQNRVYSTDFIR
VYKKIKDLIPSYIS
>Tmden_0745 Deoxyguanosinetriphosphate triphosphohydrolase
MFKKLLSNQRYCNKDEIKEDEQQQYYRSSFHKDYDRVIFSNSFRRLSKKT
QVHPLSKNDHVHNRLTHSLEVASVGRSLGLRAGEFLSKKYPQTDIDPYDV
AYIIQTACLAHDIGNPPFGHAGEEVIKEWFNKKKNETFLKELSEDELEDF
IHIDGNAQSFRVVSQIENNLFNGGMRLTFATLGALVKYPYASNRCKFTCK
SKFNFFQSEAEFFKLMFDELGLSRKDGSYKRHPLSYLMEAADDICYGLLD
LQDAVELKIITLKDTKNIFSLICGEREVEVIYEDNDYSDIKKVSRLVAIS
IHNLALHTMGVFEDNFDAIMSDEQPRDLIELFINKEYKSAIKEAKKLASA
KIFNEKRKIELELGAYNIIETLLDNLIHATYDFYKKEDETKLSFRYKRAL
ELMGEDRPKKEQSLYNMYQRVVDYIVGMTDNHAKYVANQLNGMGI
>Tmden_0264 Twin-arginine translocation pathway signal
MEVSRRDFMHICAIFGIGMATISSAAPRGAAQISLKDIFSFKDTGNFTLL
HMCDLHAHLKPLFWREPSTLISAPNLVGTPGFLCGDAFAKHYGLEPSSLD
AYFDTHIDFESLAKKFGKMGGVAHIKTVLDHVRKTRGADNVLFLDSGDTW
QGTGVALKSNGEAIVKAQNYLGVDVMVGHWEFTYGKKRVKELIGMLDAKF
ISQNIIGDDSFSDEFEELIFEPYTIEERGGAKIGIIGQSFPFTSTANPKE
FTQGWSFGLRLESLQEYVNELKDEHKVDCVVLLSHDGFSVDQEVARKVQG
IDFILSGHTHDPSPMPIVIDGTVIVIAGSHGKYIGRLDIDAKNGKVNNYE
YKLIPIASNIIPADPAGVKLVDELYAPYAAEMSEVLGKTKNILYKRDTFF
STFDQLINDAILDEMKCDISFTPGYRWGTTVLAGENILMDNVYEMCGITY
PNVYTFELEGNKIAKLLEDIADNVFNENPLYQQGGDMSRLGGATYDITVG
NPNGKRITNLKIGGKNIDLKKIYIVSSWGGNLQNAGSNLQKAKTRAVYDV
VRDYIKRKKVVDVSNKGNVKLVDFDCGCPTKGSRSCD
>Tmden_0868 Histidine triad (HIT) protein
MCIFCKIINNEIPSNIVLENKKFLAFNDINPKAPTHILVIPKLHVESFNE
VTPKSMKKMTKFMQDVAKEAGVEQSGYRIITNIGEDGGQEVKHLHFHLLG
GAKLAWPDLIDNNPKNDTDKKSTPNPKNRAKK
>Tmden_2050 Phosphoribosylformylglycinamidine cyclo-ligase
MSQISYKDAGVDIDAGNSFVENIKPLVKSTKILGVLGGIGSFAGAFELPQ
GFKEPVMLAATDGVGTKLKLAIDSGIHNTVGIDLVAMCVNDLLCNFGTPS
FFLDYYATGKLDVKTATSVVAGIAEGCIRAECALIGGETAEMPGMYSHDD
YDLAGFAVGVAEKCEMDRVSMVKAGYKLIALPSSGLHSNGFSLARKVLFE
KMNLNFNDDFNGEPLIQTLLEPTKIYVKTFKALKEHIVALAHITGGGIVE
NLPRVLPEGLMAEIKKESIRVLPIFELIAQHVESEEMYRAFNMGVGMILV
VKEEDVAVVLSKTDGYLIGEIKEGKREAKLI
>Tmden_0489 Phosphoribosylformylglycinamidine synthase I
MKVTILQFPGTNCEYDAQHAFKSLGAETEILWHKSDTIPSDTDLLIVAGG
FSYGDYLRSGAIAKFSPVMKAVIKYADDGGKVLGICNGFQVLTESGLLPG
ALKRNESLHFLSKHHHLKVINNENIFLEKLDKGDIVNIPIAHHDGNYYID
DSGLKELYANNQVLLKYCDENGNDKNPNGSIDSIAGICNKERNVFGLMPH
PERAMEAILGSDDGIKMLQGFLRA
>Tmden_0021 Deoxyguanosinetriphosphate triphosphohydrolase
MQAHDRFYKIDKDFRNPYARDRDRIIHSSSFRKLEYKTQVFLNQEGDFFR
TRLTHSIEVSQIARSITSHLGLNESLAEAIALAHDLGHTPFGHIGGDTLD
ECLKDDGFKNGFDHNFQSFRVVSSLERRYKNFDGLNLTFATLEGILKHSY
PYKKSFLPPFIDENFNLETHPSIEAMVVDRADEIAYITHDIDDGLNSGLI
RFEDLKESPLIEDILQKVKDEGIGEDEDEMFRYRFVSHLINHLVYSLIYF
SKDKIDNSKIYSASLSSKSELPIGFEPTLESEIKKLKKLLFKKLYQHKDI
MIKMYAGKQAIKGLYIGLHEEPKMMPKFYLEQLQSRSKHRVIADYIASMS
DRHALSFYNEMYGRL
>Tmden_2068 Orotate phosphoribosyltransferase, Thermus type
MNVKKIYMDADALLEGHFKLSSGNHSQFYLQSAKVLEDPKTAKLLADALA
LQIKESALEIDTVCAPALGGLIAGFALASALDVRSIFAERVDGVMNLRRG
FEIKKGERVLMCEDIITTGGSAMEAAEVVKSLGGEIVGVAALANRGFCKR
QNSDVTTKPNCKLPQDIPFFALDDFTFEMYAPEECPMCKSGSEAIKPGSR
GN
>Tmden_1126 Thymidylate kinase
MYIAIEGIDTAGKSTQIAKLQEHFSDAIITKEPGGTEAGKEIREIVLNAK
IKSKKAEFLLFLADRAEHIQEVIEPNLSKMIISDRSVVSGVAYALVQGEI
SETAILHLNRFATGGIYPQKIFLLQLTNEELSLRLSQKKLDGIELRGIEY
LLKIQDALIKASNLLNIELVLIDATKNIDSITQEILNNINI
>Tmden_0075 Adenylosuccinate synthase
MPSRKADLIVGIQWGDEGKGKIVDRLAKEYDMVCRSQGGHNAGHTIWVDG
VRYALHLIPSGILNPKAVNVIGNGVVLSPESIIKEMLQFENLEGRLFISD
KAHLNLSYHSLIDQAREKLKGDKAIGTTGKGIGPAYSDKINRVGMRVGEL
LNPEKLCERIVEHFEQNRDIFAILNINMPNKNELLEELKGYSEKLSPFIT
DTTQLIWRALDKENKRVLLEGAQGTMLDIDHGTYPYVTSSSTISAGACTG
LGINAKDIGKVIGIVKAYCTRVGNGPFPSEDLGKDGKLLGERGHEFGTTT
GRARRCGWFDAVACRYASRLNGCDELALMKLDVLDGFDEVKVCVAYELNG
AQIDYLPANLDDVKPIYKSFKGWDKTEGARRFEDLPKEAQDYIKIIEEIT
KTKVGIISTSPEREDTIIL
>Tmden_0147 CMP/dCMP deaminase, zinc-binding
MLSDENFINIAIEIAKASKCVSKQVGAVIVKDGRILSTGYNGTPAGYINC
REHWEDKYTHEHHEWSKTYEIHAEMNAIIWAARKGISIENATIYVTLEPC
SECSKNIIASGIQRIVYLKPYEHTHSEVISKFIKDNNVVIQKLQE
>Tmden_2095 Adenylosuccinate lyase
MIERYSREEMSSKWTMQAKYQAWMDVEKAVVKAWNRLGLIPNDDAKKIID
NAGFSIERIDEIEAITRHDLIAFTTSVSETLGEESRWFHYGMTSSDTVDT
AVALQMKSSLELVIEDVKMIMESIKKRAMEHKMTLMVGRSHGIHGEPITF
GLVLAVWYDEMARHLENLEQTLVVISVGQVSGAMGNFAHAPLELEEFTCE
ELGLKPAPASNQVIQRDRYARLATALALMASSIEKFAVQVRHWQRTEVYE
CEEYFAAGQKGSSAMPHKRNPILTENITGLARMIRAYAIPAMENVALWHE
RDISHSSTERFWLPDSFITTDFMLHRMNNVIANLTVYPQNMMKNLNLTGG
LVFSQRVLLELPLKGVSREDAYRIVQRNAMKVWQEIQQGKPTTNEKGESL
YLNHLLADEELRASLSEEAIRECFNYDYYTKNVDRIFDRVFRK
>Tmden_1831 Guanine deaminase
MKHSIFMKKAIKEATFGVERGDGGPFGAVIVKDGKVIAKAHNRVLKLNDA
TAHAEIEAIRKASKKLLTYDLSECEIYTTCMPCPMCMGAIRWANIKSVYF
GATSQDADDIGFRDKEFYEKDFLELKNIQRAECLELFEMWQKKEDKRLY
>Tmden_0013 Ribonucleoside-diphosphate reductase
MNRKKIYNPESNENVNDRRIFGGNPTGIFELNDIKYQWAYNLWEMMLNNT
WFPKEVDMTRDVSDYKQITDVEKASYDKALAQLIFMDSLQTNNIMDNINP
YVTSPEINLILVRQAYEEALHSQSYAVMVDTISTNSKEIYELWRRDMMLK
GKNDAIARVYEELSKNPTEHNFVKACFANQILEGIYFYSGFAYIYTLARS
GKMLGSAQMIRFIQRDEVTHLVLFQNLINSLRKERPDLFNEKLKEEVIEM
FKEAVALEVAWGKYITGGQILGLTDAIIEQYIQYLADDRLTSVGFAKLYN
VTNPIKWVDDFSKFNDQKTNFFEGTVANYSKGSLTFDDDF
>Tmden_0905 Amidohydrolase
MIFKSATICEANGERVCDVRVEDGIIAEIGTDIKGENIVDAKGCYLLPLL
VDINIKTPDSNLNAKNIKIVSTEALAGGIGHIVLNPDSTPAIDNEIVLEF
AQNGLHELRGAKVDLMINTLKEDTTLSNIAILLKRGAISPYMSTIAKNDV
AIKIAQYAQMYGVTIFCKAEDNSLISSGVMLDGDVSSKLGLAGIPDLSEV
LHVSRMIEIARHFKIKILFKAIASPRSIYLINKAKSEGVNVTCEVSIHHI
LNSDESCKGFNTTAKLNPPLASKTDMLLLQEALKNSQIDILTTLHQPSSP
LRKEVAFYDAAYGCDGLLHAMSLYYTKLVKSKMITMSRLLELCVINPLQA
IGQDGSEIKVGAKASFMLFDPNKKVIIDEKLSLYNGEELYGEIREVFND
>Tmden_0080 Carbamoyl-phosphate synthase, small subunit
MSMELLKKRAWIYLENGIFLEANSFGAESTVVGEIVFNVSMSGYQEIMSD
PSYAGQFVTFTMPEIGNVGVNAQDMESKSAHAKGMIVRKYQDRYSSFRAE
DSLSNFLKKQNVMGICDIDTRYLTKMLREEGSMMMIASTEISNKDELKKI
LQNSSRIEHVNYIEQVSTKVAYKHTQSTYNDREFKFDEAPASEANIVVLD
FGVKTNILNELVSAKIGVEVIPNNFSGDELIKRYNNKEIDGVFLSNGPGD
PLVLKHEQREIKKLIDAKVPMFGICLGHQLLSIAHGYDTFKLKFGHHGGN
QPVKNMRTGLVEITAQNHNYNVPDNIVEVAEVTHTNLFDNTIEGLKYNDS
PIFSVQHHPESSPGPKESRYIFNEFLSLIKR
>Tmden_1775 Nucleoside-diphosphate kinase
MERTLSIIKPDAVAKGVVGKILDRFESNGLKIAATRKMQLSRADAEAFYA
VHSERPFFGDLVDFMISGPVVVSVLEGEGALIKNRNLMGATNPKEAEAGT
IRADFAENIDANAVHGSDSLENAAVEIAFFFSEREIS
>Tmden_1768 HIT family protein
MIIYEDDEFYVENEKSEIPWLKIFTKEPYRELGDVPKDLRVKIWEVYDAI
EDEMRAYYNPKKINMASFANMLPRVHIHVMARFEEDSYFPNPMWGEKLRV
AKLNLPDEEKFFKKVKEALQNR
>Tmden_2092 conserved hypothetical protein
MIICAGNSETFDFATPMGVGLLEMTINLTRAALFDKPEFLLFVGSAGSYG
EYNIFDIVESKTAANIELAFLSNDAYTPLDNVISTNIDQTKKDVIVNSSN
YISTNEELTKKFLKLGIGIENMEFFAVLSVAKEFDIPAGGIFCITNYTNK
NAHNDFLKNHEEAKKLLDLHVKRRVEELTKK
>Tmden_2080 CTP synthase
MTKYIFVTGGVLSSLGKGITAASIGTLLKHSGIQVGMLKIDPYINVDPGT
MSPLEHGEVFVTKDGAETDLDIGNYERFLDTSYLKSSNFTTGQVYSAVIE
RERAGGYLGQTIQVIPHIVGEIVKRIKEAGEGHDILIVELGGTVGDIEGL
PFMEAIRQMKHDDEVEGTFFVHVTLIPFIKAAGELKSKPTQHSVQELRRI
GITPQMIIARSENALPKTFKKKLAMSCDVSSDSVIEALDAASIYDVPISF
LRQNILKPISKELSLGELNPNMEKWDSLVKKIVQPQNRIVLGFVGKYLEL
KEAYKSLTEALIHAGAHLDTRVDIHWVDSEKIEERGAEALLGDCDSVLVA
GGFGNRGVEGKIKAIEYARVNKIPYLGICLGMQLTLVEYARNVLGYEGAN
SIEFDENTPYPMIYLIDNFLDQSGNTQLRTHKSPMGGTLRLGEYPCDTLE
GSIIRKAYHGEKTIHERHRHRYEANPTYRKALEDAGMIVTGESNGLIEAV
EIKDHPWFLGVQFHPEFTSRLQTPNPSILAFVEATLAISQEE
>Tmden_0491 Phosphoribosylaminoimidazole-succinocarboxamidesynthase
MEKRELIYEGKAKKLFSTDDENLLISEFKDDLTAFNGEKKSSEVGKGALN
NKISTELFKLLEKSGIQTHFVKMLDDNHLLHKKTKVILIEVIVRNIATGS
LSKNLGIKDGTVLPFTLVEFDYKNDALGDPKLNDQHALILGLVEYQDELD
KLRRMARQINDILKPYFAQKGLNLVDFKLEFGKDSSGNIILIDEISPDNC
RFWDIESGEKMDKDRFRQGLGGLRVAYEQVLSRILAK
>Tmden_1636 Ribose-phosphate pyrophosphokinase
MRGYKIFAGSASVEFAKEVCQILDVPLAKATVKKFSDGEISVQIAESVRG
RDVFIIQSTGAPSNDNLMELLIMTDALRRSSASSITAVVPYYGYARQDRK
AAPRVPITARLVADMYEAAGIDRVVTIDLHAGQIQGFFNIPVDNLYGSVT
FENYIRSKNLKNPIIASPDIGGVARARYFASRMGLDMVIVDKRREKANES
EVMNIIGNVEGKDVIMIDDMVDTAGTMIKAATALKNKGASSVMACATHAV
LSGKAYENIENGELDELIITNTLESKPHKKIIVLTVAPLFAEVIRRVYHN
ESVNSLFA
>Tmden_0461 Aspartate carbamoyltransferase
MKHLIRTDDFTTQEIESILADAELFSDGRFDRILRDKIIITLFFENSTRT
RSSFEIAAKRLGAEIVHLDVANSSTKKGETLVDTAMNLDAMGPHAIIVRH
QNSGVAKILSNHTKASIINAGDGAHAHPTQALLDLFTLKKHFKNLEGKKI
AIVGDIKNSRVANSNIELLSRFKMEVILVAPPQFLPQSDLRTTHYLEDII
DEVDAIMSLRTQTERHSSQTYASLKDYASDFCITSEVVGDRDIIILHPGP
VHRNIDICDALLADKRCKVLEQVANGVAIRMAVLKKLIYDV
>Tmden_1087 Adenylate kinase
MKKLFLIIGAPGSGKTTDAELIAKENDNITHYSTGEMLRAEVATKSELGL
EIDNYISKGLIVPIEVAIKTITNAIKNAPTDIIIIDGYPRSMEQLNALDE
YLHIDSSLELASVIEVRVSEETARDRVLGRARGADDNTEVFDNRMKVYTE
PLFDIQAFYNAKNLLHVISGEGTIETIVSEMGSFVKAKI
>Tmden_0017 Thymidylate synthase complementing protein ThyX
MQSIYGIKYTKPEVVLIQETGIGVAEAAARTCYDSFENSENRAIQYIEKN
MPDSSTCREINGIEESNLLNDLAWTYFHHSILEHANLSFLVRGTSRGVLQ
EHARHRMQAISVRSTRYTMSSVINAFVASMSSNDRDFFIDKVLSFDMFVT
CDKEYNKIEIGAMYDKLFYQSKKVEDFNEIAVATSSLDLLEKFKGTPEAL
FDALESGKKKRNVGDAFKHIISDNVKVDMVVTFNLRSLKNYFTLRDSGAA
YFQIRWLAQEMMRKTPSKYLDLIIKKR
>Tmden_0717 Uridylate kinase
MANKRVLVKFSGEALAGEAGYGIDTKILNFISQEIKSLVEANIEVGIVIG
GGNIIRGVTAAQDGIIKRTSGDYMGMLATVINGIAMQEACEHAGLQVRMQ
TAIKMEQIAEPYINRRAVRHLEKGRVVIFAAGTGNPFFTTDTAATLRAVE
IGAEVIIKATKVDGVYDKDPNKFSDAIKLQELSYEQALNDNIKVMDDTSI
ALAKDNSLPILVCDMFKKGNLLDILQNGNMKNCSIVK
>Tmden_0071 Ham1-like protein
MRLILATSNRGKVKEIKALCKDFKVIPYSELIEEFEIIEDASTFKGNALI
KARAVFKVLSQKDEYKDMVVLADDSGISVDVLGGAPGIYSARYASKGASD
KENLYKLIEDVKKSGAKGSPAHYTAAIAIVTKNYEYSVHGWMYGDVIAEV
RGDGGFGYDPMFIPLGYDKTLGELDDDTKKNISHRAKALSLAKIILQTL
>Tmden_0424 Phosphoribosylamine--glycine ligase
MKILILGSGGREYSIARAILNENEAHELFFMPGNGATSSLGKNLNIKDYN
DLALFAKESGIELTIVGPEAPLVDGVVDIFKSNNLVIFGPSKEAAQLEGS
KVYMKNFLAKYNIPTARYIETASIEEAFKFTDKLQTPIVVKADGLCGGKG
VIIALTHDEAKVAISEMLSGKSFGDAGKKVIVEEFLDGYELSMFAVCDGD
DYILLPAAQDHKRVMDGDQGPNTGGMGAYAPTPLVDEELYQKVRDRIIRP
TLDGMKMENAPFEGVLFIGIMVVNGEPITLEFNVRFGDPECEILMPLMTS
SVSDMFYKAATNRLGEIKVEFSSQFAVGVVMASANYPYSNSTPAEIILDN
VYHEEIEKYTHISYAGVSMIDDKLYADGGRVLVCVGLGDTIKEARDRAYM
RCGQVHFAGKKLRTDIAYQALFKEVK
>Tmden_1088 Adenylate kinase, subfamily
MRIILLGAPGAGKGTQAGFLTKRYNIPQISTGDMLRAAIKAGTEMGKMAK
EAMDTGKLVTDEIIIGLVKDRIEEEDCKNGFLLDGFPRTLAQADAVTNAG
INIDAVIEIDVPDSEIVKRMSGRRAHLASGRTYHLVYNPPKVEGKDDITG
EELVQRDDDKESVVLDRLRVYHEQTSPLIGYYKNQATKLDTLTYITVDGT
ADIADVEAAIVSKLG
>Tmden_0033 Phosphoribosylglycinamide formyltransferase 2
MLFSAPLKSNSKKIMLLGSGELGREVAIEAQRLGLEVIAVDRYQNAPAHS
VAHRSYVVNMQDKDALLEIIYREKPDYILPEIEAISIDALFEAEDKGYNV
IPNANAVSKTMNRKNIRTFAAEVLELKTGAYEFVTTKEMLVSAAGRLGFP
CVIKPVMSSSGHGQSVARSASDIDASWEIAKEARGDASELIVEAFVDFDY
EITMLTARNGKETVFCEPIGHEQRDGDYVFSWQPMQMSEIAKQRAEDMAK
KITDGLGGRGLFGVELFIKGDEVYFSEVSPRPHDTGMVTLITQSQSEFAL
HLRAVLGLPLEFTFYGEGASAAFKSEVHNFSPVIHVDESLFSKNSFVRIF
GKPEAHKGRRLAVALVFDKAEQALQRARELITKVKDS
>Tmden_1467 Carbamoyl-phosphate synthase, large subunit, glutamine-dependent
MPKRTDIHTILLIGSGPIIIGQACEFDYSGTQAVKTLKELGYRVVLINSN
PATIMTDPEFADRTYIEPIREDIIAKIIKDEKVDAVLPTMGGQTALNVAT
SMYKKGMLEGVEFLGASPEAIHKGEDRSAFNKAMIKIGMDLPKSRNAYSV
EEALEVALEIGFPVISRASFTLAGGGSGVAYNMEEFKILAQEGISASPVS
EIEIMESMLGWKEYEMEVIRDKADNCIIVCSIENFDPMGVHTGDSITVAP
ALTLTDKEYQRMRDASFDILREIGVDTGGSNVQFSIDPKTGRMIVIEMNP
RVSRSSALASKATGYPIAKVATLLAVGFTLDEITNDITGTPASFEPVIDY
VVTKIPRFTFEKFPEAQSTLSTSMKSVGEVMAIGRTFKESIQKALCSLET
GLCGFDPIDADFDFIKHEIRRPNADRILYVAEGFRRGMSIEEMFDTCNID
PWFLYQIEEMIKVESIIDKKILSDETFMRSVKVDGFSDKRIAQLISQKSE
TKITEDDVYKAKKTLGVNLEYNEVDTCAAEFEALTPYLYSTTNITKLPNV
KNRVSEAKKVLILGGGPNRIGQGIEFDYCCVHAAFALKEMGIETIMYNCN
PETVSTDYDTSDVLYFEPIDFEHVREVIENEKPDGVIVHFGGQTPLKLAN
ALTKIGANIAGTPSHVIDLAEDREQFSNFVNSHGLKQPANGLARTKDEAH
DIALRLGFPVLVRPSYVLGGRGMRIVYSQEELRQYMDLAVLVSNDAPVLV
DKFLDQAIELDVDAICDGVDVYIGSVMQHIEEAGIHSGDSACSLPPVSLS
KELIDQVEAQTKTIALGLGVRGLMNVQYAIYQDEIYLIEVNPRASRTVPF
VSKATGMPLAKVATRVMVGETLKNALNYYDKYNIVMEENGLLKPRLKGHI
SVKEAVFPFHKLYGADLVLGPEMKSTGEVMGISSNFGISFAKAQIAAGNR
IVTEGTCFLSFVDTDKKYASEIASALHRHGFKLLATKGTQASIEEAGIPC
EVVLKISEGRPNIEDSMKNDAIDMAINTSDNNTSKKDAIVIRQEVLKRNI
PYFTTLSAARALILALDEMKNDSWTSSRALQDFLA
>Tmden_1447 Orotidine-5'-phosphate decarboxylase
MQLCVALDLPTKEENLELIGKIKDYDVWLKVGLRSYIRDGEDFLKDIKKI
NPDFKIFLDLKLYDIPNTMADAAESIISLGVDMFNVHASAGKRAMREVMV
RLERYEKRPIVLAVTALTSFNEDEFGKIYGDSISKKADQFAKDAYESGLD
GVVCSAYESSSIKNITNRDFMTLTPGIRPFGEDSGDQQRVADVAFAKNAH
VDFIVVGRPIYNSKNPAEVIRRILEQI
>Tmden_1796 Guanylate kinase
MNHKTGAILVLSGPSGAGKSSLIKEVIDDIGECYFSISTTTRPIREGEVD
GVHYHFVSESEFKKDIEDEFFLEYAVVHSNYYGTSIKPVKKALKSGKLVI
FDIDVQGNATIINRLGDITTSVFISPPTLSELKKRLEARSTDTKDVIERR
IEMAKREMQRVSEYDFLIVNDNLQEAAKTLRIIADAARVKIPSNEINDFV
RSWEDI
>Tmden_1617 Formyl transferase-like
MKRVAILASYNGSGFDALHVALKNGELSIEIPLVISNNSSAKVLKNAINY
GIDNFVVNSKTDQNPDEKIEELLNEYQCEYLFLSGYMKKVGINISKNFKV
INSHPALLPNYGGKGMYGRFVHEAVIKNSEKTSGVTIHEVNENYDEGKII
LQKELILDKDESVDSLEKKIKELEQITIVEAFKNI
>Tmden_0661 Ppx/GppA phosphatase
MAKRVAVIDIGSNSLRMVIYEKTSRFAFHILYEAKSRVRISQNAYQNGGN
LQEIPMQRAFDALSNFIPIIASFKARKTLCVATSALRDAPNKKEFLNRVK
NCLGLNIKVIDGQREAYLGAIACANLLPEQQSALSIDIGGGSTEFALISK
KNILKSVSLNLGTVRLKELFFDFNNIDGAKEYIDKELALLDEMDASTIIG
IGGTFRAISSAILTNSNYPMDKLHAYKPSYDDFEEFLEKILSSDDENLKK
LGIKSSRFDVIKSGALILLRVFKKFNIKELLTSGVGVREGVFLADLLRTS
NDRFPLNYNTSVRYILDAYIENISYANQISRVSKELFDLVADRLNMDKKY
RHELSIASKLCMSGNSIHFYSSNKHSYELIQDALEFGFTHEQIALIATLA
RFSKRKLPSASHVDKFSSLLPHNEQLNALSYILSLSVALLSHMPRNIDFK
LTLRDDTIEVESKNSLYLARECVEKLEPLKNSPLMVKFL
>Tmden_1392 Adenosylhomocysteine nucleosidase
MKIAIMGAMPEEISPILEKIGSYKSTSYAGNKYYEATYQGVELVIAYSKI
GKVFSALSAATMIEHFGATKLLFSGVAGAISTNLKVGDLIVATKLSQHDL
DITAFGHPYGYVPEGSVFVEADKDMIELSKKVALEMGKSVQEGIIATGDQ
FVANEERKNWIGTTFGADALEMEGGSVGVVCNALNIPFFILRSISDAADM
DASFSFDEFLESSAKESAEFIMKMVDELVALPLQDIK