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# Haemophilus influenzae 86-028NP, 86-028NP

>NTHI1134 HIT-like protein
MDRLIRRTFYREQTMAEETIFSKIIRKEIPANIVYQDELVTAFRDISPQA
KTHILIIPNKVIPTVNDVTEQDEVALGRLFSVAAKLAKEEGIAEDGYRLI
VNCNKYGGQEVFHLHMHLVGGEPLGKMLAK
>NTHI1009 conserved hypothetical protein
MKSHVRSFKTYIRDEIIKKGGWVNAHAHADRAFTMTPEKIGIYHSSNLQQ
KWDLVDEVKRTSSVDDYYARFCQSIELMISQGVTAFGTFVDIDPICEDRA
IIAAHKAREVYKHDIILKFANQTLKGVIEPTARKWFDIGAEMVDMIGGLP
YRDELDYGRGLEAMDILLDKAKSLGIMCHVHVDQFNNPSEKETEQLCDKT
IEHGMEGRVVGIHGISIGSHSKEYRYKLYEKMRKAKMMMIACPMAWIDSN
RKEDLMPFHNALTPADEMIPEGITVALGTDNICDYMVPLCEGDLWQELSL
LAAGCRFPHLDEMVNIASINGRKVLGLELI
>NTHI1825 deoxyguanosinetriphosphate triphosphohydrolase-like protein
MQKNEIKQSDMKPLIIDSSWTERFLPDPPREKDNRPPFRRDRGRILHSAA
FRCLQAKTQIHAIGENDFYRTRLTHSLEVAQIGSSLVAQLKFLETFESLS
QTLNIDKNELQKQLKPLLPSNDLIESLCFAHDIGHPPFGHGGETALNYMM
AEQGGFEGNAQTFRILTKLEPYTENAGMNLTRRTLLGVVKYPALLGVASP
QYAELNFSRNIDPRFVRIHDWIPGKGIFRDDLKMFNWLLENLSENDRTLF
CQFKKVRENPAESLHTRFKSLDCSIMELADDIAYGVHDLEDAIVTGVVNP
HQWQAAHVALKQIPSAWLHENIDSISQRLFSDKHFERKQAIGALVNFFIT
NVRWKLTANFDEPLLRYNAELPPEVIAALGVFKKFVWDYVIRNVDTQRIE
YKGQRMLTEMFQIFESDPERLLPRNTENRWRNAPKEGKKRIICDYIAGMS
DAHALRVYQQL
>NTHI0645 predicted nucleoside permease
MSVLSSILGMVVLIAIAVLLSNNRKAISIRTVVGALAIQVGFAALILYVP
AGKQALGAAADMVSNVIAYGNDGINFVFGGLADPSKPSGFIFAVKVLPII
VFFSGLISVLYYLGIMQVVIKVLGGALQKALGTSKAESMSAAANIFVGQT
EAPLVVRPYIKNMTQSELFAIMVGGTASIAGSVMAGYAGMGVPLTYLIAA
SFMAAPAGLLFAKLMFPQTEQFTDKQPEDNDSEKPTNVLEAMAGGASAGM
QLALNVGAMLIAFVGLIALINGILSGVGGWFGYGDLTLQSIFGLIFKPLA
YLIGVTDGAEAGIAGQMIGMKLAVNEFVGYLEFAKYLQPDSAIVLTEKTK
AIITFALCGFANFSSIAILIGGLGGMAPSRRSDVARLGIKAVIAGTLANL
MSATIAGLFIGLGAAAL
>NTHI1073 conserved hypothetical protein
MDAAKVRSEFDEKMMRYALELADKAEALGEIPVGAVLVDDARNIIGEGWN
LSIVQSDPTAHAEIIALRNGAKNIQNYRLLNSTLYVTLEPCTMCAGAILH
SRIKRLVFGASDYKTGAIGSRFHFFDDYKMNHTLEITSGVLAEECSQKLS
TFFQKRREEKKIEKALLKSLSDN
>NTHI0468 adk, adenylate kinase
MKIILLGAPGAGKGTQAQFIMNKFGIPQISTGDMFRAAIKAGTELGKQAK
ALMDEGKLVPDELTVALVKDRIAQADCTNGFLLDGFPRTIPQADALKDSG
VKIDFVLEFDVPDEVIVERMSGRRVHQASGRSYHIVYNPPKVEGKDDVTG
EDLIIRADDKPETVLDRLAVYHKQTSPLIDYYQAEAKAGNTQYFRLDGTQ
KVEEVSQELDKILG
>NTHI1938 apt, adenine phosphoribosyltransferase
MTTQLDLIKSSIKSIPNYPKEGIIFRDITTLLEVPAAFKATIDLIVEQYR
DKGITKVLGTESRGFIFGAPVALALGLPFELVRKPKKLPRETISQSYQLE
YGQDTLEMHVDAISEGDNVLIIDDLLATGGTVEATVKLVQRLGGAVKHAA
FVINLPELGGEKRLNNLGVDCYTLVNFEGH
>NTHI1816 cdd, cytidine deaminase
MQELIKRTLPQDDALNQAIVNELRSQNWAGFLNYSQVQQLCHNFELTPLK
LAMHLLPLAASYSHTAISHFNVGAIAIGEQGDFYFGANQEFANSAIQQTI
HAEQSAISHAWLRNERRISDMVVNYTPCGHCRQFMNELHGAEKISIHLPH
SQNNPLHSYLPDAFGPKDLDIAAHLLAEENHDLVADHQDDLVNQAILAAN
QSHCPYSNSPHGIAILFKNGDVVTGRYAENAAFNPSLPALQTALNFAYLN
DKKLSDIERIVMAEKALKLSHKTMAETLLSTLTSVELEYYSL
>NTHI1949 cmk, cytidylate kinase
MKLTLLDKPYKTWKLVIISRMVMRGNCLYNAQNFDNERIICMGMIITVDG
PSGAGKGTLCYALAEKLGYALLDSGAIYRVTALAALQRKTDLTNETDLAE
LARHLDIQFIPQNGEVNILLAGMDVSRLIRTQEVADAASKVAVFQKVRSA
LLQLQQDFAKNDGLIADGRDMGTVVFPNAQVKLFLDASAEERAKRRYKQL
QNKGINGNFAQILAEIKERDLRDRNREVAPLKPADDALLLDSTALSINEV
IDQALSYIQEKVSV
>NTHI0741 cpdB, 2',3'-cyclic-nucleotide 2'-phosphodiesterase
MINRRHFIQIGATSILALSANRFAMAKGKSDVDLRIVATTDVHSFLTDFD
YYKDAPTDKFGFTRAASLIRQARAEVKNSVLVDNGDLIQGNPIADYQAAQ
GYKEGKSNPAVDCLNAMNYEVGTLGNHEFNYGLNYLADAIKQAKFQIVNA
NVVKAGTEEPYFTPYVIQEKSVVDNNGKTHKLKIGYIGFVPPQIMVWDKA
NLQGKVETHDIVKTAQKYVPEMKKKGADIIVALAHTGPSDEPYQEGAENS
AFYLADVPHIDAVIFGHSHRLFPNKEFAKSPNADIVNGTVKGVPESMAGY
WANNISVVDLGLTEHKGKWIVTSGKAVLRPIYDAKNKKVLAENDPEITAL
LKPVHEATRKFVSQPIGKATDNMYSYLALVQDDPTIQIVNQAQKAYVEKV
APNVAAMAGLPILSAGAPFKAGGRKNDPTGYTEVNKGELTFRNAADLYLY
PNTLVVVKATGEQLKEWLECSAGMFKQIDPTSDKPQSLIDWEGFRTYNFD
VIDGVNYEYDLTKPARYDGECKLINPESHRVVNLTYQGKPVDPKAEFLIA
TNNYRAYGNKFPGTGDQHIVYASPDENRQILADYIKVTSEKEGSVNPSAD
KNWRFVPISGNDKLDVRFETSPSEQAAQFIKEKAQYPMKQVGTDEVGFAV
YQIDLSK
>NTHI0859 cya, adenylate cyclase
MECNLAQAKQWVSALDQRRFERALQGSGDAFQHVLAIAPLLLHLNHPQLP
GYVIHAPSGIANFLASDYQKKWLTNEYSIHYADHKPSTLKSAVNFHEVLP
PILGVYVMGSFGSISQTSSSDLDTWICVRDGLSPDEYTLLTQKAKRISEW
AMQFNVEINFYLMDQQRFRNEHYADPLTIENSGSAQYMLLLDEFYRSAVR
LAGKPLLWLHLWVENEKDYEKQVARLITEGEIDPNDWVDFGGLGQFSANE
YFGASLWHLYKGIDSPYKSVLKILLLEAYSKEYPNTCLIARTFKRDLLSG
NTNPDHHFDPYIAILAKVTQYLTALSEFKRLDFVHRCFYVKATEDFARYQ
ANNWRIRYMEILAQEWGWSAETVKHLNKRPFWKIKAVKENHDNIMKFLML
SYRNLVEFARKHHIHSSVVPQDINILSRKLYTAFEELPGKVSLLNTQISH
NLSEAHLTFVEVRGNKHFKDSWYLINQPIHHIMFSKERVIEYGESLNKLV
SWAYFNHLLTEKTELSIFSKNVTLSTLQRFVTNLRQSFPSTIAKQPKNSD
LLNQCEIRSLFIAINLTTDPTSKVEEVLTGISSRDLFSFGSLEQSLVGSI
DFTYRNVWNEIRTLHFEGQNAILLALKVLSNKIYRGVNRPDSIQVYCYSE
RYRQDLRQLVMGLVNRCVSIQVGDIQQPCQTSRLRVAGKNWQLFFEDRGI
SLQEIGNESVCNDAESAVDFDEVLQTPIEDGETNQESRRYPPEMDAFASE
GFLQFFFEDNSDHSFNVYILDESNHLEIYRHCDGEKDEKVREINQLYQNA
KQEGDKNPYNIVQHNFNYPQFYQLQNGKNGISIVPFKFRQMNK
>NTHI0219 dcd, deoxycytidine triphosphate deaminase
MRLCDTDIERYLDDGIISLTPRPNNDKINGATIDVRLGNSFRVFREHSAP
FIDLSGPKEEVSAQLESVMSDEILIPEGEAFFLHPGTLALATTLESVKLP
ANIIGWLDGRSSLARLGLMVHVTAHRIDPGWEGKIVLEFYNSGKLPLALR
PNMVIGALSFEVLSGEAKRPYSSRKDAKYKNQQSAVASRIDEDKE
>NTHI1280 deoC, deoxyribose-phosphate aldolase
MTSNQLAQYIDHTALTAEKNEQDISTLCNEAIEHGFYSVCINSGYIPLAK
EKLAGSNVKICTVVGFPLGANLTSVKAFETQEAIKAGANEIDMVINVGWI
KSQKWDAVKQDIQAVFNACNGTPLKVILETCLLTKDEIVKACEICKEIGV
AFVKTSTGFNKGGATVEDVALMKQTVGNIGVKASGGVRDTETALAMIKAG
ATRIGASAGIAIISGTQDTQSTY
>NTHI0644 deoD, Purine nucleoside phosphorylase
MTPHINAPEGAFADVVLMPGDPLRAKYIAETFLQDVVEVTNVRNMLGFTG
TYKGRKISIMGHGMGIPSCSIYAKELITEYGVKKIIRVGSCGTVRMDVKV
RDVIIGLGACTDSKVNRIRFKDNDFAAIADFDMAQAAVQAAKAKGKVVRV
GNLFSADLFYTPDVEMFDVMEKYGILGVEMEAAGIYGVAAEYGAKALTIC
TVSDHIRTHEQTTAEERQLTFNDMIEIALDSVLIGDAL
>NTHI1127 dut, deoxyuridine 5'-triphosphate nucleotidohydrolase
MKKIDVKILDSRIGNEFPLPTYATEGSAGLDLRALIDESFEIQPGETKLI
PTGLSIYIADPNLAAVILPRSGLGHKHGIVLGNLVGLIDSDYQGPLMVSM
WNRGNEPFKIEVGDRIAQLVFVPVVQAEFNIVEDFQQTERGEGGFGHSGK
Q
>NTHI2054 gmk, guanylate kinase
MSQGNLYILSAPSGAGKSSLISALLASDSSTQKMVSVSHTTRAPRPGEVE
GVHYYFVSKEEFESLIEQDLFLEYAKVFGGNYYGTSLPAIEENLAKGIDV
FLDIDWQGAQQIRKKVPSVKSIFILPPSLPELERRLIGRGQDSEEVIAER
MSKAISEISHYDEYDYVIVNDDFEKTLKDLQSILQSERLTKDYQQKQNAM
LIQQLLAK
>NTHI0796 gpt, xanthine-guanine phosphoribosyltransferase
MSEKYVVTWDMFQMHARRLSERLLPASQWKGIIAVSRGGLFPAAVLAREL
GLRHIETVCIASYHDHNNQGELQVLHAAQVPNGGEGFIVVDDLVDTGNTA
RAIRQMYPNAKFVTVFAKPAGAELVDDYVIDIPQNTWIEQPWDLGLTFVP
PLSRK
>NTHI0814 gpt2, xanthine-guanine phosphoribosyltransferase
MSEKYVVTWDMFQMHARKLSERLLPASQWKGIIAVSRGGLFPAAVLAREL
GLRHIETVCIASYHDHNNQGELQVLHAAQVPNGGEGFIVVDDLVDTGNTA
RAIRQMYPNAKFVTVFAKPAGAELVDDYVIDIPQNTWIEQPWDLGLTFVP
PLSRK
>NTHI0326 guaA, glutamine-hydrolyzing GMP synthase
MTNIHNHKILILDFGSQYTQLIARRVREIGVYCELWAWDVTEQQIREFAP
TGIILSGSPESTTEENSPRAPEYVFNASVPVLGICYGMQTMAMQLGGLTE
TSDHREFGYASVSLENSTALFANLNDNSTASEPKLDVWMSHGDKVTRLPE
NFKVTGTTPTCPIAAMSDENRRFYGVQFHPEVTHTKKGLELLTNFVVNIC
GCETKWTAENIIEDAVARIKEQVGDDEVILGLSGGVDSSVVALLLHRAIG
KNLHCVFVDNGLLRLHEGDQVMEMFGDKFGLNITRVDAESRFLGELAGVS
DPEAKRKIIGKVFVDVFDDESKKLTNVKWLAQGTIYPDVIESAASKTGKA
HVIKSHHNVGGLPDYMKLGLVEPLRELFKDEVRKIGLALGLPAEMINRHP
FPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRNSGWYEKTSQAFSVFL
PVKSVGVMGDGRKYDWVISLRAVETIDFMTAHWAHLPYDLLGKVSNRIIN
EVNGISRVVYDISGKPPATIEWE
>NTHI1321 hpt, hypoxanthine phosphoribosyltransferase
MKKHHVDVLISENDVHARIAELGAQITKFYQEKQIDSLVVVGLLRGSFMF
MADIVRQINLPVEIEFMTTSSYGTGMTTNHDVRITKDLDGDIKGKHVLIV
EDIIDTGYTLEKVRDILNLREPASLAICTLLDKPSRREVEVLVEWVGFEI
PDEFVVGYGIDYAQRHRNLGYIGKVVLEE
>NTHI1389 mtnA, MTA/SAH nucleosidase
MKIGIVGAMAQEVEILKNLMADRTETRVASAVIFEGKINGKDIALLQSGI
GKVAAAIGTTALLQLAKPDCVINTGSAGGVAKGLKVGDIVISDETRYHDA
DVTAFGYEKGQLPANPAAFLSDKKLADLAQEMAEKQGQSVKRGLICSGDS
FINSEDKIAQIQADFPNVMGVEMEATAIAQVCYAFNVPFVVVRAISDGGD
GKASMSFEEFLPLAAKQSSALVLGMIDRLS
>NTHI0303 nadN, NAD nucleotidase
MLLSKKSATFALSAFAMLFTSVALAKEAPQAHKAVELSILHINDHHSYLE
PHETRINLNGQQTKVDIGGFSAVNAKLNKLRKKYKNPLVLHAGDAITGTL
YFTLFGGSADAAVMNAGNFHYFTLGNHEFDAGNEGLLKLLEPLKIPVLSA
NVIPDKSSILYNKWKPYDIFTVDGEKIAIIGLDTVNKTVNSSSPGKDVKF
YDEIATAQIMANALKQQGINKIILLSHAGSEKNIEIAQKVNDIDVIVTGD
SHYLYGNDELRSLKLPVIYEYPLEFKNPNGEPVFVMEGWAYSAVVGDLGV
KFSPEGIASITRKIPHVLMSSHKLQVKNSEGKWAELTGDERKKALDTLKS
MKSISLDDHDAKTDKLIAKYKSEKDRLAQEIVGVITGSAMPGGSANRIPN
KAGSNPEGSIATRFIAETMYNELKTVDLTIQNAGGVRADILPGNVTFNDA
YTFLPFGNTLYTYKMEGSLVKQVLEDAMQFALVDGSTGAFPYGAGIRYEA
NETPNAEGKRLVSVEVLNKQTQQWEPIDDNKRYLVGTNAYVAGGKDGYKT
FGKLFNDPKYEGVDTYLPDAESFIKFMKKHPHFEAYTSSNVKFNASTDAL
PKK
>NTHI1039 ndk, nucleoside diphosphate kinase
MMTERTFSIIKSDAVKRNLIGAILTRFEQNGFKIIASKMVRLTREQAEGF
YAEHQGKEFFAPLVEYMMSSPIVVSVLEKENAVKDYRTLIGTTNPETAEE
GTIRKDFALSQRENSVHGSDSIENANREIAYFFTDCEIFER
>NTHI1961 nrdA, ribonucleoside-diphosphate reductase alpha chain
MNKSLMVTKRDGTQEQINLDKIHRVITWAAEGLDNVSVSQVELRSHIQFY
EGIRTSDIHETIIKAAADLISKDSPDYQYLAARLAIFHLRKKAYGHFDPP
RLYDHVKKLVRMEKYDQALLDDYTREEWDTMDGFIDHWRDMTFSYAAVKQ
LEGKYLVQNRVTGEIYESAQFLYLLVSASLFSKYPKETRLDYVKRFYDAT
STFKISLPTPIMAGVRTPTRQFSSCVLIECDDSLDSINATASAIVKYVSQ
RAGIGINAGAIRALGSEIRGGEAFHTGCIPFYKYFQTAVKSCSQGGVRGG
AATLYYPIWHLEAENLLVLKNNRGVEDNRVRHMDYGVQLNKLMYQRLIKG
GEITLFSPSDVPGLYEAFFADQDKFEELYVKYEQDPTIRKRTVKAVEIFS
LLMQERASTGRIYIQNVDHCNTHSPFDPQVAPVRQSNLCLEIALPTKPLQ
HINDENGEIALCTLSAFNLGKIENLDELEELADLAVRSLDALLDYQDYPV
VAAKRSSLARRSLGIGVINYAYYLAKNGVRYSDGSANDLTHRTFEAIQYY
LLKASMNLAKEQGACEYFNETTYAKGILPIDTYKKDLDSLTQEPLHYDWE
SLRKDIQEFGLRNSTLTALMPSETSSQISNATNGIEPPRGHVSIKASKDG
ILKQVVPEYENLMDNYELLWDIPSNDGYLHLVGIMQKFVDQAISANTNYD
PKRFEDGKVPMKVLLKDLLTAYKYGLKTLYYQNTRDGAEDVQEDLDDGCA
GGACKI
>NTHI1962 nrdB, ribonucleoside-diphosphate reductase beta chain
MAYTTFSQNKNDQLKEPMFFGQNVNVARYDQQKYETFEKLIEKQLSFFWR
PEEVDVSQDRIDYAALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLV
SIPELETWIETWTFSETIHSRSYTHIIRNIVNDPSIVFDDIVTNEEIIKR
AQDISSYYDDLIRDSQLYGLYGEGTYTVDGKECVVTLRSLKKQLYLCLMS
VNALEAIRFYVSFACSFAFAERRLMEGNAKIIKFIARDEALHLTGTQHIL
NIMAAGQDDPEMAEIAEECKQEAYDLFVAAAEQEKAWADYLFKDGSMIGL
NRDILVQYVEYITNIRMQAVGLPLPFQTRSNPIPWINAWLVSDNVQVAPQ
EVEVSSYLVGQIDSKVDTNDFDDFSL
>NTHI0088 nrdD, anaerobic ribonucleoside-triphosphate reductase
MSNFGVIKRDGSRAEFEIQRIINAIKKAASAVNISDEFYCHQIGQEVGNE
IFTRHQGEIDINQIQKVVEDKLMASRYPEIARAYIEYRHDRDLAREKRSQ
LTKEIEGLIEQSNVELLNENANKDAKVIPTQRDLLAGIVAKHYAKHHILP
RDVVEAHEKGEIHYHDLDYAPFFPMFNCMLVDLEGMLSRGFKMGNAEIEP
PKSIGTATAVTAQIIAQVASHIYGGTTINRIDEVLSPYVQISYEKHLKHA
QEWNVPDVEGYAKALIEKECFDAFQSLEYEVNTLHTSNGQTPFVTFGFGL
GTSWQSRLIQQAILKNRIRGLGKNHKTPVFPKLVFTIKKGLNQNKGDPNY
DIKQLALECASKRMYPDILNYDQVVKVTGSFKAPMGCRSFLGAYEENSHE
IHDGRNNLGVVSLNLPRIALESKNEEDFYRTLDERLAIAKKALMTRVARL
ENTKARVAPILYMEGACGVRLKADENVAQIFKNGRASISLGYIGIHETIN
ALYKKGHIFDDEQLREKGIAIVRHLSEAVKRWQKETGYAFSLYSTPSENL
CDRFCRLDTKKFGVIEGITDKGYYTNSYHLDVEKKVNPYDKLDFEMSYPP
LASGGFICYGEYPNIQHNLKALEDVWDYSYDRVPYYGTNTPIDECYECGF
TGEFECTSRGFVCPKCGNHDSTKVSVTRRVCGYLGSPDARPFNAGKQEEV
KRRVKHL
>NTHI0366 orfM, predicted xanthosine triphosphate pyrophosphatase
MKQKIVLATGNKGKVKEMADVLSDFGFEVIAQTDLGIESPEETGLTFVEN
ALLKARYASEKSGLPAIADDSGLVVSALNGAPGLYSARYAGEEGNDAKNR
EKLLAELAHVAKDQRQAKFVSCIVFLQHPTDPSPIIAEGECCGVIGFEEK
GENGFGYDSLFFSPEQGCTFAELETAEKKKISHRAKALNILKNKL
>NTHI1433 prsA, Ribose-phosphate pyrophosphokinase
MPDIKLFAGNATPELAKRISERLYISLGDATVARFSDGEIQVQINENVRG
ADVFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRR
VRSARVPITAKVVADLLSIVGIDRVLTCDLHAEQIQGFFDVPVDNVFGSP
VLIHDILKKSDLENPIVVSPDIGGVVRARAVAKLLNDTDMAIIDKRRPRA
NVAQVMHIIGDIADRDCILVDDMIDTGGTLCKAAEALKERGAKRVFAYAT
HAVFSGAAAKNLASDAIDEVVVTDTIPLSEEMKAIGKVRVLTLSSMLAEA
IRRISNEESISAMFN
>NTHI1407 purA, adenylosuccinate synthetase
MGKSVVILGAQWGDEGKGKIVDLLTDRVKYVVRYQGGHNAGHTLIINGEK
TVLRLIPSGMLHPNVTCLIGNGVVVSPEALMKEMGELESRGIKVRERLLI
SEACPLILPYHVAMDHAREAALGKKAIGTTGRGIGPAYEDKVARRGLRVG
DLFNKEAFAEKLKNILEYYNFQLVNYYKVEPVDYQKTLDDVMAIADVITG
MVADITTILDTARKNGEHILFEGAQGTMLDIDHGTYPYVTSSNTTAGGVA
TGSGFGPRNLDYVLGIIKAYCTRVGGGPFTTELFDDVGAEIARKGNEFGA
VTGRPRRCGWFDAVAIRRAIQLNSISGFCMTKLDVLDGFDEVKICVAYKM
PNGEIVEYAPLAAKDWEGVEPIYETLPGWKENTFRITDVNKLPQNCINYI
KRIEEVTGVPIDILSTGPDRVETMILRDPFAA
>NTHI0758 purB, adenylosuccinate lyase
MQLSTLTALSPLDGRYQDKVTPLRAIFSEFGLMKFRVVVEVRWLQKLAST
ADITEVPPFSTQANAFLDGIVANFNEADAARIKEIERTTNHDVKAVEYFL
KEKIQNEVELVNVSEFIHFACTSEDINNLSHALMLSTARDEVILPEWQKL
IDEITRLAEEYKTIPLLSRTHGQPASPSTVGKEMANVVYRLKRQFKQLQN
AEILGKINGAVGNYNAHLSAYPNIDWHKFSEEFVTSLGIQWNPYTTQIEP
HDYIAEFFDAVVRFNTIIIDFDRDLWGYIALNHFKQRTIAGEIGSSTMPH
KVNPIDFENSEGNLGLANAVMTHLGQKLPISRWQRDLTDSTVLRNLGVGL
GYCLIAYASTRKGMSKLEVNQPHLLEELNQNWEVLAEPIQTVMRRYGIEK
PYEKLKELTRGKRVTEQAMREFIDKLDIPQEEKLRLQKLTPATYIGAAVE
LVEKLS
>NTHI2033 purC, phosphoribosylaminoimidazole-succinocarboxamidesynthase
MRYNTHQFLLSYRCKTMTQQLPILSLKKIYSGKVRDLYEIDDKRMLMVAS
DRLSAFDVILDDPIPRKGEILTQISNFWFNKLAHIMPNHFTGDSVYDVLP
KEEADLIRNRTVVCKRLNPIKIESIVRGYLTGSGLKDYKQTGTICGLKLP
EGLVEASKLPEAIFTPSSKEEVGNHDINISYAECEKLIGADLAAQVKEKA
IALYTVAAEYALTKGIIICDTKFEFGLDENGTLTLMDEVLTPDSSRFWSV
DTYQAGTNPPSFDKQFVRDWLENSGWNKQAPAPKVPENIIQKTVDKYQEA
LDLLTK
>NTHI1052 purD, phosphoribosylamine--glycine ligase
MNILIIGNGGREHALAWKVAQSPLADKVFVAPGNAGTALEHKVENVNISA
TDIPALVKFAQDKQIGLTIVGPEAPLVIGVVDAFREAGLKIFGPAKAAAQ
LEGSKAFTKDFLARHKIPTAEYQNFTEVEPALTYLREKGTPIVVKADGLA
AGKGVIVAMTLQEAEDAVRDMLSGNAFGEAGSRVVIEEFLDGEEASFIVM
VDGKNVEPMATSQDHKRVGENDTGLNTGGMGAYSPAPVITPEIHSRIMKE
VIYPTVNGMAAEGSVYTGFLYAGLMIMPNGQPKVIEFNCRFGDPETQPIM
LRLKSDLVELCLKACDGKLDEVISQWDPRASLGIVLAAEGYPKDYRKGDE
ISGLPKSAVKNEKVFLAGVAEQEGKLVTNGGRVLCVTALGESVFEAQQKA
LKLAEQIQWSGRFYRRDIGYRAVEREQAK
>NTHI1425 purE, phosphoribosylaminoimidazole carboxylase catalytic subunit
MSKTAQIAVVMGSKSDWATMQEATQILDELKVPYHVEIVSAHRTPDKLFE
FAENAQKNGYKVIIAGAGGAAHLPGMIAAKTLVPVLGVPVKSSMLSGVDS
LYSIVQMPKGIPVGTLAIGPAGAANAGLLAAQILASWDAELLSRLQSFRE
SQTSNVLDNPDPRT
>NTHI1378 purF, amidophosphoribosyltransferase
MCGIVGIVSQSPVNESIYAALTLLQHRGQDAAGIVTVDDENRFRLRKANG
LVSDVFRQEHMLRLQGNAGLGHIRYPTAGSSSVSEAQPFYVNSPYGVTLV
HNGNLTNSVELKEKVFKTARRHVNTNSDSELLLNILANHLDHIPQNHLDP
QDIFYAVRKTHNDIRGAYACVAMIIGHGMVAFRDPFGIRPLVLGKREENG
KTDYMFASETVALDIVGFEFVRDIAAGEAVYVTFDGELYSQQCTESAVLN
PCIFEYVYFARPDSTIDGVSVYAARVHMGEKLGKKIAKEWADEIDNIDVV
IPIPETSTDIALQIARVLGKPYRQGFVKNRYVGRTFIMPGQAQRISSVRR
KLNTIKAEFKDKNVLLVDDSIVRGTTSEQIVEMARSAGAKKIYFASAAPE
IRYPNVYGIDMPSCDELIAYGRNVEEIAHLIGVDKLIFQDLTALTESVQL
ENPAIQGFDCSVFTGEYITGDISPEYLDKIALQRNDSAKKKREKQASNLE
IYNEQ
>NTHI1051 purH, bifunctional purine biosynthesis protein PurH
MTDRPIRQALLSVSDKTGIVEFAQGLVKRGVKLLSTGGTAKLLAQNGLPV
IEVSNYTGFPEMMDGRVKTLHPKIHGGILGRRGTDDAIMQQHSIEGIDMV
VVNLYPFAATVAKPDCTLTDAVENIDIGGPTMVRSAAKNHKDVAIIVNNN
DFNAILTEMDKHQNSLTFETRFDLAIKAFEHTAQYDSMIANYFGQLVKPY
HIAEEEEANAKCGQFPRTLNLNFVRKQTMRYGENSHQNAAFYVDLNVKEA
SVATANQLQGKALSYNNIADTDAALECVKEFDEPACVIVKHANPCGVALG
KDILDAYNRAYQTDPTSAFGGIIAFNRELDEKTANEIVERQFVEVIIAPK
VSAEAQEVMKRKKNVRLLECGEWTSRSERLDFKRVNGGLLVQDADLGMVG
VDDLKVVSKRQPTEQELKDLLFCWKVAKFVKSNAIVYAKDNQTIGIGAGQ
MSRVYSAKIAGIKAQDEGLTVAGCVMASDAFFPFRDGIDAAAKVGIQCVI
HPGGSMRDQEVIDAADEHNMVMVLTGMRHFRH
>NTHI1424 purK, phosphoribosylaminoimidazole carboxylase ATPase subunit
MQNSTLYPTVYVLGNGQLGRMLGYAGAPLDIYVEPLAFNAPVFDLPENAI
ITAEIERWEKTPLTELLGNHKNFVNQHVFGLLADRFAQKSLLDELNLSTS
PWCLLKDKTQWNDVFQTVGEKVVVKRRTGGYDGRGQWIISDENKADITDD
LFGEVIAEKFIPFDYEVSIVGARFKNGEKRFYPVTHNLQQNGILRYSVID
NAFPQQSAQQKQAETMLGKIMDKLGYVGVMAMECFVVGDKLLINELAPRV
HNSGHWTQLGCAISQFELHLRTLLDLPTPDLQIFAPSVMVNLIGTNHNPK
WLNIPFAQLHWYGKEVRAGRKVGHINLSHPNKAVIIQQLEKLRIELPEDY
QSGLNWAIEKLK
>NTHI0909 purL, phosphoribosylformylglycinamidine synthase
MQTFALFVIIRLFFYFSFIRNCNMTVKTFRGSPALSEFRLTQLQQKCQQY
QLPITSVYAEYLHFVEQKTSLVEDEIVKLQALLHYGSMFSELKPAGYCLI
VTPRVGTISSWSSKATDIAHNCGLSKVNRIERGIAYYFNIERDLTEAELA
TLKDLLHDRMLETVLNHETEAALLFTQQEPKALTTIDILNGGRQALERAN
IALGLALADDEMDYLVESFTALKRNPQDVELYMFAQANSEHCRHKIFNAD
WIIDGKKQDKSLFKMIKNTFEQTPDFVLSAYKDNAAVMEGSKVGRWFPDP
DGQYRVHQEDAHILMKVETHNHPTAISPFPGAATGSGGEIRDEGATGRGA
KPKAGLTGFSVSNLVIPNFEQPWENPLSKPNRIASALDIMIDAPLGSAAF
NNEFGRPALLGYFRTYEEKVNSFAGKEVRGYHKPIMLAGGIGNIRGEQVQ
KGEIPIGAKLIVLGGAAMNIGLGGGAASSMDSGKSKEDLDFASVQRENPE
MERRCQEVIDRCWQLGEENPILFIHDVGAGGLSNAMPELVHDGRRGGKFD
LRSILCDEKGMSPLEIWCNESQERYVLAVAPENLELFTALCERERAPFAV
IGEATQAEHLILHDSHFDNNPIDLPMNVLLGKTPKMTREVLSKTVENQSL
KTEGIQLKEAFHRVLRLPVVAEKTFLITIGDRSVTGMVARDQMVGPWQIP
VSDVAVTTASLDSYHGEAMAMGERSPVALLNFSASARLAVAEAITNIAGT
HIGEMKRIKLSANWMSAAGHTGEDAGLYEAVKAVGEELCPALGLTIPVGK
DSMSMKTTWIDNGEQKSVTAPLSLVISAFARVEDVRKTLTPQLRTDKGLS
SLLLIDLGEGHNRLGATALAQVYKQLGDKPADVVKVQRLKDFYNAMQTLV
AEDKLLAYHDRSDGGLITTLAEMAFAGHCGVEVDISALGDNDLAVLFNEE
LGAVIQVADSQLESVREVLKAHNLLGITHQLGTVTADDRFEISRGSHKLF
SEKRSELRSIWAELTYQMQRLRDNPECAEQEFEAKKNPDDKGLSAFLTYD
VNEDITAPFINKGVKPTIAILREQGVNSHYEMAAAFDRAGFNAIDVHMSD
LMIGRRNLAEFNAMVACGGFSYGDVLGAGGGWAKSILFNPKLHEQFSQFF
INPNTLTLGVCNGCQMISNLAEIIPGTENWPHFVRNKSERFEARVSLVKI
NEVDSVWFAGMAGSHMPIAVSHGEGQVKFKSVEQFAGLKAQGIIAAQYID
NNGSPTELYPANPNGSAEGITAITNLDGRVAIMMPHPERVFRAVSNSWHP
ENWTEDGAWMRLFRNARMVF
>NTHI1704 purM, phosphoribosylformylglycinamidine cyclo-ligase
MSNTQLSYKDAGVDIHTGNELVERIKGDVKRTRRSEVMGGLGGFGALCAL
PTKYKEPILVSGTDGVGTKLRLAIDLKKHDTIGQDLVAMCVNDLIVQGAE
PLFFLDYYATGKLDVDVAASVIKGIADGCEMSGCALVGGETTEMPGMYHE
GDYDLAGFCVGVVEKSEIIDGTAVKTGDTLIALGSSGAHSNGYSLIRKVL
EVSGANPADLLEGKPLSEHFLAPTKIYVKSILQLIKQTEVHAIAHLTGGG
FWENIPRVLPANTKAVIDESSWQWPAIFNWLQEKGNISRYEMYRTFNCGV
GMVISLPEKEVETALALLEQAGEKAWVIGKIEHLGEGEAQVEIQ
>NTHI1706 purN, phosphoribosylglycinamide formyltransferase
MKKIAVLISGQGTNLQTIIDACHLGDIPAKIACVVSNKADAYGLVRAKQA
QIPQAVFLRKNFSNNLEMDDAIGDYLQSLAVDLIVLAGYMKILTPKFTQR
FAGKILNIHPSLLPKYAGLNTYQRAIEAGDNEHGTTVHFVNEEVDGGAIV
LQAKVPIFPEDSIEEVEAKTREQEYQIYPLVIKWFTEGRLRLKDNLAYLD
GKALPKSGYANE
>NTHI1463 purU, formyltetrahydrofolate deformylase
MIEKKILLTDCPDDKGLIAKITNICYKHQLNILHNNEFVDFETKHFFMRT
ELEGIFNEATLLEDLKYSLPEETNCRLIGTQRKRIVILVTKEAHCLGDIL
MKNYYGALDVEIAAVIGNHDNLRELVERFNIPFHLVSHENLTRVEHDKLL
AEKIDEYTPDYIVLAKYMRVLNPEFVARYPNRVINIHHSFLPAFIGAKPY
QQAYERGVKIIGATAHFINNELDQGPIIMQNVINVDHTYNAEAMMRAGRD
VEKTVLSRALDLALHDRIFVYKNKTVVL
>NTHI1745 pyrD, dihydroorotate dehydrogenase
MYQLFRHGIFQMDAEKAHDFTIQCLKLASNPLFQPILKSLIHAPKGFPKT
VMGVNFPNPIGLAAGADKNGDAIDGFGTLGFGFLEVGTVTPVAQDGNAKP
RQFRLIEAEGIINRNGFNNNGIDYLIENVKNARYKGVIGINIGKNKFTSL
EQGKDDYIFCLNKAYNYAGYITVNISSPNTPDLRQLQYGDYFDDLLRSIK
DRQAILANQYNKYVPIAVKIAPDLTESELVQIADTLVRHKMDGVIATNTT
VSRDTVMGMKNAEQQGGLSGKPLQHKSTEIIKRLHQELKGQIPIIGSGGI
DGLQNAQEKIEAGAELLQVYSGLIYHGPKLVKELVKNIK
>NTHI0380 pyrE, orotate phosphoribosyltransferase
MEQYKRDFIEFALSRNVLKFGEFTLKSGRKSPYFFNAGLFNTGADLARLG
EFYAAAIQASAVDFDVVFGPAYKGIPIGTSVSVALFNRYGIDKPVCFNRK
EVKDHGEGGNLIGSPLQGKILLVDDVITAGTAIRESMELISANKAELAAV
LIALNRKERGKGELSAIQEVERDYQCQVLSIIDLDDLMQFIEQDPRYSSH
LPEMRAYRAEFGV
>NTHI1944 pyrF, orotidine 5'-phosphate decarboxylase
MTSKIIVALDYEKEAEALALVDQIDPSLCRLKVGKEMFTTLGINFVKQLH
QRNFDVFLDLKYHDIPNTVARAVRSAADLGVWMVDLHASGGLRMMEEAKK
ILEPYGKDAPLLIAVTVLTSMEDLDLLQIGINASPMEQVLRLAHLTQRAG
LDGVVCSPQEVEILRNTCGKEFKLVTPGIRPIGTDFGDQRRVMTPTAAIR
AGSDYLVIGRPITQADNPAEVLRSINVSIG
>NTHI1238 pyrG, CTP synthase
MATNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPG
TMSPTQHGEVFVTQDGAETDLDLGHYERFIRTKMTKRNNFTTGKIYSEVL
RKERRGDYLGATIQVIPHITNEIKDRVIAGAQGHDVVIVEVGGTVGDIES
LPFLEALRQLAVQVGREHTLFMHLTLVPYIPTAGEVKTKPTQHSVKELLS
IGIQPDVLICRSDRMIPPNERAKIALFCNVAERAVISLKDVNSIYQIPAL
LKSQGLDDFVCERFRLTCPEADLTEWEQVLYKQANPVGEVTIGMVGKYTE
LPDAYKSVNEALKHAGLTNRLSVSIKYIDSQDVETKGVEVLKGVDGILVP
GGFGYRGVEGKIRTAQYARENKIPYLGICLGMQIALIEYARNVAGLTKAN
SSEFDKDCEQPVVALITEWQDAEGNTEVRTDESDLGGTMRLGAQQCHLVS
GSHARELYGKETIEERHRHRYEVNNTLLPQIEKAGLKVTGLSADKKLVEI
IEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAAYENHKKSVK
>NTHI1225 pyrH, uridylate kinase
MSQPIYKRILLKLSGEALQGEDGLGIDPAILDRMAVEIKELVEMGVEVGV
VLGGGNLFRGAKLAKAGMNRVVGDHMGMLATVMNGLAMRDSLFRADVNAK
LMSAFQLNGICDTYNWSEAIKMLREKRVVIFSAGTGNPFFTTDSTACLRG
IEIEADVVLKATKVDGVYDCDPAKNPDAKLYKNLTYAEVIDKELKVMDLS
AFTLARDHGMPIRVFNMGKPGALRQVVTGTEEGTTIC
>NTHI0589 pyrR, PyrR bifunctional protein
MEKIIIDHDRFLRTISRISHEIIEKHQTLDDLVIVGIKRRGAEIAELLQR
RVEELSGINLPSMELDITFYRDDLTLVDQEDKMPVYSGSSQYLNIQDKTV
ILVDDVLFTGRTIRAAMDALTDFGRAAKIELVIFVDRGHRELPIRADYVG
KNVPTSRDELVQVRTEKQDGCYEVAILGK
>NTHI0655 tdk, thymidine kinase
MAKLYFYYSTMNAGKSTTLLQSSYNYRERDMSTLVYTAAIDDRFGVGKVT
SRIGISQDAFLFRSETNLFDEINEHLKKEKVHCVLVDEAQFLSKQQVYQL
SDVVDKLKIPVLCYGLRTDFQAELFEGSKYLLAWADQLEELKTICYCGRK
ANFVLRLNDQGEVIKEGAQIQIGGNDSYLSVCRLHYKEKCGQI
>NTHI1072 thyA, thymidylate synthase
MKQYLDLCRRIVSEGEWVANERTGKHCLTVINADLEYDVANNQFPLITTR
KSYWKAAIAEFLGYIRGYDNAADFRALGTKTWDANANVNAAWLANPHRRG
VDDMGRVYGVQGRAWRKPNGETIDQLRKIVNNLTKGIDDRGEILTFFNPG
EFDLGCLRPCMHTHTFSLVGDTLHLTSYQRSCDVPLGLNFNQIQVFTFLA
LMAQITGKKAGKAYHKIVNAHIYEDQLELMRDVQLKREPFPLPKLEINPD
IKTLEDLETWVTMDDFKVVGYQSHEPIKYPFSV
>NTHI0586 tmk, thymidylate kinase
MPNKSAEENMKGKFIVIEGLEGAGKSSAHQSVVQVLHELGIQDVVFTREP
GGTPLAEKLRHLIKHETEEPVTDKAELLMLYAARIQLVDNIIKPALMQGK
WVVGDRHDMSSQAYQGGGRQLDPHFMLTLKETVLGDFEPDLTIYLDIDPI
VGLARARGRGELDRIEQMDLDFFHRTRARYLALVKENPKAVVINAEQSIE
LVQADIERAVKNWWKSNEK
>NTHI0218 udk, uridine kinase
MSNPSCIIIAITGASASGKSSIASTVHKELCNELGCQEIGIITEDSYYKD
QSHLEMTERVKTNYDHPNSMDRDLLIQHLKNLKNGSAVDVPVYSYVEHTR
TNETTHFTPKRIVILEGILLLTDERVRQLADISVFVDTPLDICFIRRLQR
DMEERGRSLQSVIDQYRATVRPMFLQFIEPSKQYADIVIPRGGKNRIAIN
MLKAQILHLLNQK
>NTHI0389 udp, uridine phosphorylase
MIIRRFIMSDVFHLNLTKAQLKGATLAIVPGDPARSERIAKQLDNPEFLT
STREFTSWLGYINGQPIVVCSTGIGGPSTSICVEELAQLGVRTFLRIGTT
GAIQPHINVGDVLITTAAVRLDGASCHFVPLEYPAVANFECTTALYNAAK
AKGIEPYVGVTVSSDTFYPGQERYDTYSGKVYRDYQGLLKQWQDLNVMNY
EMESSTLFTMCSALGLRAGMVAGVIVNRTQQEIPNEATIKQTEEKAVSVV
IAAAQALLS
>NTHI1940 upp, Uracil phosphoribosyltransferase
MKLVEVKHPLVKHKLGVMREAEIDTKKFRELATEIGSLLTYEATSDLETE
KVTINSWNGPVEIDRIKGKKVTVVPILRAGLGMMDGVLEHVPSARISVVG
IYRNEETLKPVPYFQKLASDLEERLAIVVDPMLATGGSMIATLDLLKAKG
CKHIKVLVLVAAPEGIKALEAAHPDIELYCASIDSHLNEQGYIIPGLGDA
GDKIFGTK
>NTHI1941 uraA, probable uracil permease
MTNQTSSFPSENQSKLKQSFVGLQMLFVAFGALVLVPLITGLDSNTALLT
AGVGTLLFQFCTGKQVPIFLASSFAFIAPIQYGVQTWGIATTMGGLAFTG
LVYFALSTLVKLRGAEALQRFFPPVVVGPVIIIIGMGLAPIAVDMSLGKN
SNYAYNDAVLVSMVTLLTTLSVAVFAKGLMKLIPIMFGITVGYILCLFLG
LINFQPVIDAPWFSLPKLTTPEFNLEAILYMLPIAIAPAVEHVGGIMAIS
SVTGKDFLKKPGLHRTLLGDGVATAAASLVGGPPNTTYAEVTGAVMLTRN
FNPNIMTWAAVWAIAISFCGKVGAFLSTIPTIVMGGIMMLVFGSIAVVGI
STLIRGKVDVTEARNLCIISVVMTFGIGNMFVDVGNVSLKGISLCAIVAI
ILNLVLPKAKNEVE