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# Candidatus Blochmannia pennsylvanicus str. BPEN, BPEN

>BPEN_310 adk, adenylate kinase
MIRIIFLGPPGSGKGTQAHLIANKYNIPNISTGTMLRQALTRSTHKSYEL
HKNIMHTGDLVNDEFMVQLISTRINQNDCRNGFLLDGFPRTILQAKSMKQ
CKIFVNYIIEFFASDSVIIDRIAGRRIHVGSGRTYHIKFNPPRNYGLDDI
TGEILTTRKDDHEEAIRKRLSNYYQHTEPVLDYYREESKYKKMKYFSVDG
NRDISKIYKELINIISS
>BPEN_308 apt, adenine phosphoribosyltransferase
MTNVTDQQLELIKKSIQFVPNYPKKGILFRDITELLKNPQAYSASITLLA
YYYRNHKLTKVVGIEARGFLFSAPLALILKLGFIPARKSGRLPRDTIREP
YILEYDNGFLEIHTDSITPGDQVLIIDDLLATGGTIAAAVKLIRRLGGEV
NHAGFIIDLENLGGKSLLKEIGINSYSLVTFSNH
>BPEN_126 carA, carbamoyl-phosphate synthase, small chain
MKSALLVLEDGNQFYGYAIGAEGETVGEVVFNTSMTGYQEIITDPSYAYQ
IVILTCPHIGNVGTNEFDNESSCIQVRGLIIRDLAMVVSNFRYTLSLSDY
LVQQNIVGIAGVDTRKLTRLIREKGIQHGCIIACDMPDATLALRKAREFT
GLSGLNLVHEVSTSQRYIWNQGTWNIKSGVFCTPLYLPYRVVVYDFGVKR
NIMRILVDYGCLLTVVPAHTTAQEIIDMQPDGIFLANGPGDPNAYEYAIN
SIQTFLNTTTIPLFGICLGHQLLALASGAKTVKMKFGHHGSNHPVKDIET
NKVIITAQNHNFVVDKQTLPDTLKITHISLFDGTLQGIHHTNKPAFSFQG
HPEASPGPHDAASSLFGHFIKLIKNYRNK
>BPEN_127 carB, carbamoyl-phosphate synthase, large chain
MPKRTDIHSILLLGAGPIVIGQACEFDYSGAQACKALREEGYRIILVNSN
PATIMTDPDMADVTYIEAIQWKIIHKIIEKEHPDALLSTMGGQTALNCTL
DLERHGILKKFNIITIGATIDSICKAEDRQKFRESMKKISLETARSGVAR
DIDEAMMVLEKIGLPCIIRPSFTLGGTGGGVAYTQEEFEKLCRYRLDSYP
HHELLIDESLIGWKEYEMEVIRDIKDNCIIVCSIENVDPMGIHTGDSITV
APAQTLTDKEYQIMRNASIMVLREIGVETGGANVQFAVNPNNGRLIVVEM
NPRVSRSSALASKATGFPIAKIASKLAVGYALDELSNDITNGCIPASFEP
SIDYVVTKIPRFNFEKFPERHNKLTTQMKSVGEVMAIGRSQQESLQKAIR
GLEIGVMGLDSQIDLNHPKAFSIIVYELKNASSNRIWYIADAFRYGISLE
QVFYLTNIDRWFLVQIQELVQLENDIMLEGISCLDKNRLYCLKKKGFSDA
RLGKLTGVSENKIRTLRFIYDIHPVYKHVDACAAEFSTNTSYMYSTYDGE
CEFQFNHTNKTIMILGGGPNRIGQGIEFDYCCVHAAITLRESGYHVIMVN
CNPETVSTDYDISDILYFEPITLEDILEIIRINKPTGVIVQYGGQTPLKL
VKEMEASGISIIGTSPDAIDQAENRERFQRSIKCLGLQQPDNATVISIQS
ALKKAKNIGYPIVVRPSYVLGGRAMEIVYNEKELLFYFKNAILVSNNAPV
LLDSFLENAIEVDVDAICDGKQVFIGGIMEHIEYAGIHSGDSACSLPAHT
LSKNIQDRIRCQVKELAFKFNIKGLVNIQFAIQKDEIYIIEINPRASRTI
PFVSKATGMELAKIGTRVMIGQSLLDQGILKEVIPPYFSVKEVVLPFNKF
IGMNPKLGPEMRSTGEVMGIGRTFEEAFAKATLSSQLYMKKHGDVLLSLS
NKDTDKAVDLVTKFIKNGFMLDVTCETANILKSVGLVSQMIRPVHVTHPY
IHKKIKNGGYSYIVDTTLTDNISNDYAALLCRIALRHNVYYITTINGSFA
AAMSLAVDTTEHVVSLQDMHSKIVH
>BPEN_392 cmk, cytidine monophosphate (CMP) kinase
MNNIFPVITIDGPSGVGKGTLSRRLAKILGWNLLDSGVIYRVLALAALEN
KIDINREEKVAVLAEEIQISFINRKNNFFVSFNGKEIKKDIYTETIGNYA
SKIAVFSKVRKNLLTYQRTFCQCPGLVADGRDMGTVVFPNAELKIFLYAS
FEERERRRLHQLQKKNFGVNFKFLFSQIRERDVRDYNRQSAPLTPAIDSL
ILDSTHLSAEEVKSKVLMYIRESLVFSSRVLYNTTHNQG
>BPEN_638 dut, deoxyuridine 5'-triphosphate nucleotidohydrolase
MKIINVKIIDNRIYKHFYLPKYATSGSAGLDLSACLDKPLTIYPGKTHLI
STGIAIHISDTKIAGVILPRSGLGHKYGIVLGNLVGLIDSDYQGELIVSL
WNRGPKKYIVYPGKRIAQLVFMPIIQVRFSIVKSFIPTERGPHGFGHSM
>BPEN_641 gmk, guanylate kinase
MKNSGILCIISAPSGTGKSTLIHTVIQCDCFVYQTKLSISYTTRIKRPGE
IHGKDYYFISKKKFKYMIDKNMFFEYAMIFNHYYGTAKTDIETMLNTGIH
IVLNIDWKGAQQIRSKISKNIYTIFILPPSKKELARRLYLRGEDTEKVIV
ARMGQAMDEISHFKEYDYIIINDNFNIALMHLQSIMLSEQLRIAHQKIRY
ATLINHLLLPDI
>BPEN_546 guaA, GMP synthase (glutamine-hydrolyzing)
MKCNNHRILVIDFGSQYTQLLLRRIRELGVYSESCSWNISKSQVYAFNPN
GIILSGGPYSVIDNDSPYIPEFVFQLGIPIFGICYGMQIMSFQLGGRVER
VIAQREFGCTQVTILSKSVFINDIYDYVDDVTGRFALDVWMSHGDVVTTV
PKDFTVIGVNKYRQVAMMANEDRHLYGVQFHPEVTHTKKGKSILERFITC
ICRCKSSWKIANIIDDIVMDTRVKVGNDKVVLGFSGGIDSLVTALLLRRA
IGHQFICIYIDNGLLSNYEFDRIKNFCALNCNLDIIYLSQEQRFFNALIG
VNDPEKKRKIIGRVFTEVFEEQIRNLVAVKWLAQGTIYSDVIESGVSLSS
FKNVIKSHHNVGGFCGITDIQLLEPIRNLFKDEVRSIGLDLGIPYDIAYR
HPFPGPGLAIRILGEVKKEYCDILRRVDFIFIEELKREHLYSKISQAFAV
FLPTHSVGIQGDQRKYKWVIALRAVETIDFMTAHWAYLSYDFLNKVSNRI
VNEVEEVSRVVYDISSKPPATIEWE
>BPEN_553 ndk, nucleoside diphosphate kinase
MVCKENTLSIIKPDAVAKNIIGSIISRFETAGLIIVGAKILQLTYIQASE
FYFEHQKKYFFDSLVNFMISGPVFVQILEGNNSIQRNREIMGATDPANAL
AGTIRSDYGYNYTKNAIHGSDSKKSAIREISYFFDT
>BPEN_494 nrdA, ribonucleoside diphosphate reductase 1, alpha subunit
MNQTLLVTKRNGHHEPINLDKIHRVINWAAKGLEQVSVSQVELRSHIQFY
NGIKTSDIQETIIKAAADLISEEEPDYQYLAARLAVFHLRKKAYGQFEPP
KLYNHVLRLIKIGKYDQHLLDDYNAEEFNQMDTFIDHWRDMNFSYAAVKQ
LEGKYLVQNRVTGEIYESAQFLYILTAACLFSKYPKKTRMHYIQQFYDAI
STFKISLATPIMSGVRTPTRQFSSCVLIECDDSLDSINATSSSIVKYVAQ
RAGIGINAGRIRALGSPIRNGEAFHTGCIPFYKHFQTAVKSCSQGGVRGG
AATLFYPIWHLEIENLLVLKNNRGIDSNRIRHLDYGVQINKLMYQRLIEG
KYITLFSPSDVPGLYEAFFNNQNEFEHLYNIYENDHNIRHRKIKAIELFS
LMMQERASTGRIYIQHTDHCNTHSAFDSIAAPVRQSNLCLEITLPTKPLN
NINDHNGEIALCTLSAFNLGNIENLDDLSELSILIVRALDALLDYQHYPI
PAAQRSAVRRRSLGIGVINYAYYLAKHGVRYSDGSANKLTHRTFEAIQYH
LLRASNNLAQEKGSCEWFNDTSYSKGILPIDTYKTDLNSFINEPLHYNWE
DLRVKIKKYGLRNSTLSALMPSETSSQISNATNGIEPPRGYISIKTSKNG
ILRQVVPEFIKLKSDYELLWQIPDNRGYLQLVGIMQKFIDQSISTNTNYD
PSRFPENKVPMKQLLSDLLYAYRLGIKTLYYHNTRDGAQDVQKTLPHNQS
NICTSDACTI
>BPEN_495 nrdB, ribonucleoside-diphosphate reductase 1, beta subunit
MIYTTFSQNKNNQLLEPMFLGQPVNIARFDQQKHSIFEKLIEKQLSFFWR
PEEIDISKDRIDFQSLPDHEKHIFISNLKYQTLLDSIQGRSPNIALLPLI
SIPELEIWVETWSFFETIHSRSYTHIIRNIVNHPSLIFDDIISNKEILKR
AKDISTYYDNLIELTSYYHILGPGIHQINNNTVAVNLHELKKKLYLCLIS
VNVLEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLNATQHIL
NLMRSGSDDPEMADISTECQQESYALFLMAAEQEKNWANYLFKDGSMIGL
NKDILCQYIEYITNIRMQAIGLRTPFNIKSNVIPWINSWLSSDNVQVAPQ
EVEASSYLVGQIDPNIDENEFHDFQL
>BPEN_519 nupC, nucleoside transport protein (NUP family)
MSRIFHFVLGFTTIVILSLIVSSNPKKIRVRFIFQVLIIEILFGYFILHS
QLGSNSIRKLCTLFDTLLIFASEGTNFIFGGMHAQGLATFFLNILCPIIF
ISALIGILKYTHILVFSIRIIGTILSKINGMGKLESFNAVSSLILGQSEN
FIVYKNIIGKIPAPRMYTMAATAMSTVSLSIIGAYMTMLAPKYVVAALIL
NMFSAFIILSLLNPYVVDKEKDIDITDFYINNQNIFEIIGEYILIGFKIA
VTVAAMLIGFIALISALNFTFKILFNTSLQEILGYIFFPCAWIMGIPTDE
ILPVSSIMATKLISNEFIAIINLQNISSDLSPQTVGITSVFLVSFSNFSS
IGIIAGAIKGLNKTQGNMISQHLGFKLIYSSTLINMLSASIVGLLI
>BPEN_356 prsA, phosphoribosylpyrophosphate synthetase
MKLFTGNAIPELAQRIANRLYINLGKASVGRFSDGEVSVQINENVRGGDV
FIIQSTCAPTNDNLMELIVMVDALKRASAARITAVIPYFGYARQDRRVRS
ARVPITSRVVANFLSSVGVDRILTVDLHAEQIQGFFDVPVDNVFGSPILL
EDMTQQNFNNPIIVSPDIGGVVRARAIAKLLNDTDMAIIDKRRSRANISQ
VMHIIGDICNRDCILVDDMIDTGGTLCKAADVLKERGARRVFAYTTHPIF
SGDAYENIQNSMIDEIIVCDTIPLKPKIKSLSNVRVLTLSGMLAETIRRI
SNEESISAMFDH
>BPEN_086 purA, adenylosuccinate synthetase
MARSIVVLGAQWGDEGKGKIVDWLTSRAQYVVRYQGGHNAGHTIVVDQQK
ITLHLIPSGILHNHVTAVIANGVVLSPFSLIKEMKMLLKLGVSTCKRIFI
SASCPLLLPYHVAMDLARENHHISKAIGTTGCGIGPSYEDKVARRALRVS
DLYNLKYFKNKLKDVVDYYNFQLVYYYKTKPINYQIVLEEVMSISDILID
MVVDVPELLDDAAKRGDSVIFEGAQGSLLDIDHGTYPYVTSSHTIAGSVS
VGAGVGLNYIDYVLGIVKAYSTRVGFGPFPTELSNDTGNWLCMNGNEFGS
TTGRRRRTGWFDAVSVRYSVKINSFFSCCLTKIDVLDGLKELKICIAYRK
KNGKVIHNFPCSLEELENCVPIYEILPGWMISTVGITEFHQLPKESQLYV
KRIEELIGVPIHIVSTGSDRSAIIILRNPFDS
>BPEN_405 purB, adenylosuccinate lyase
MITLSPLTVISPIDGRYYKQTDSLRNIFSEFSFLKFRVQIEIYWLKKLAN
TIAITEIPPFTQIESDFLNKLTINFNIKDAERIKEIEKITNHDLKAIEYF
LKEKINILPNLKKISEFIHFACTSDDINNLAYGLMLTNTKKTVFLPIWKQ
IINEIKKMSINYKDIPVLSRTHGQPATPSTIGKEMANIAYRLIRQYHQLK
SIKILGKMNGAVGNYNAHVIAYPEINWRKFSEEFVISLGMKWNPYTTQIE
PHDYIAELSDCIARFNTILINFNRDIWGYIALNYFKQNHSNTTIGSSTMP
YKVNPINFENSEGNLGLANAMFNHFSAKLPISRWQRDLSDSTVLRNLGMA
MGYALIAYHSILKGIKTLTVNKEHVLTELNKNWIVLSEAIQTVMRRHNIH
ESYECTKQFINNTEINPEKIKIFIESLPLPATEKIRLQKITPLDYIGLAA
VMANDITDII
>BPEN_575 purH, IMP cyclohydrolase
MIQSSLLIRRVLISVFDKSNILEFAQSLIQRGIQLLSTGGTARILSDAGL
PVIKISEYTKLPEIMDGRVKTLHYKVYAGILGRRGLDDAIMRQYNIPPID
MVVVNFYSFNSLLAKNKKYSQEEMLDRIDISGPSMVRAAAKNYKNVAIVV
NNDSYKKILDEINLYDGLLSLDTRFHLAVKAFKYVTEYDNTISDYFNHQV
QSNYHTSMTNDHHCDQSFSYFPKNLTFMNLKFIKKQDIRYGENPHQRAAF
YMDISKKHTGSISDAQQLQGKPLSYNNIVDMDTALECAKMFDEPTCVIVK
HTNPCGVATSDTICTAYAKAYQADPISAFGGIIAFNRSLDKKTAQAIISQ
QFVEAIVAPNINRDCISIVSNKKHVRILRCGMWTPRTSDIDFKRINGGLL
IQDYDVMTNLEDLEIVTIRKPTKEEMKDALFCWKVVKFVKSNAIVCGKNC
QTIGIGTGQMNRVYAAKIATSFQERERQGTLNTKGSVMASDAFFPFSDIV
HIASEIGIKCIIQPGGSIRDQEIIKTADRHGIAMIFTHIRHFRH
>BPEN_161 pyrG, CTP synthetase
MRVNYIFVTGGVVSSLGKGIATASLAAVLEARGLSVTIIKLDPYINMDPG
TISPVQHGEVFITEDGAETDLDLGHYERFIRTKMRHHNNFTAGKIYADVL
RKERRGDYLGATIQIIPHVTDTIKKWLIAGAFGHDVLLVEIGGTVGDIES
LPFLEAIRQMVMEVNREQTLYIHLTLVPFIAVSGELKTKPTQHSVKELLS
IGIQPDILICRSDRVISNSERKKISLFCNVPKQAIIALQDVDSIYKIPAL
LKDQGLDNYICKRFNLNCPEANLSDWEEVIYYQEHPIGEVTVGMVGKYIE
LVDAYKSVTEALKHAGIKNRFIVNIRLINSQDVEKLGIEKTLKGLDAILV
PGGFGYRGVEGKILSAQYARENNIPYFGICLGMQVALIEFARHVAGMPEA
NSTEFVTNCKCPVIALITECKDENGIFITHNDNTNLGGTMRLGNQACYLI
KGSLTHQIYGKSTILERHRHRYEVNNMLLKHITHAGLSCVGFSKKNNLVE
VIEYPNHPWFIGSQFHPEFNSTPREGHPLFIGFIKAAIEYQHRHNKLI
>BPEN_281 pyrH, uridylate kinase
MVTHTKPIYRRIVLKMSGEALQGAEGFGIDTTILNRMVTEVKELVKIGIQ
IGIVMGGGNLFRGAELVKSGMNRIVGDHIGMLATIMNGLAMRSALNHAYV
HSHLMSAIPLNGVCDHYNWMKAINLLSNNWVVIFAAGTGNPLFTTDSAAC
LRGIEIKADVVLKATKVDGVFSTDPIQHPDATLYEQLSYQDVLERELKVM
DLTAFTLAREHNLPIRIFNINKLGALKRIIMGYKEGTLITK
>BPEN_557 tadA, tRNA-specific adenosine deaminase
MYEIENVDTIWMRHAIALAAHAEIIGEISVGAVLIQNGKLISYGWNSSII
CHDPSAHAEIVALRTGGKVLGNYRLLGTTLYVTLEPCMMCIGAIIHARVY
RLVCGAKNSKTEQRSWLKNTLRHPMNNHHVFLTTGVLEKECAYQLNKFFK
RQRKT
>BPEN_447 tdk, thymidine kinase
MAQLYFYYSAMNAGKTTALLQSSYNYQERGMRTVLYTADMNSRDNRYKQI
KSRIGLYASARVFNIKTNFFDQVVTIHQKDIIHCVLVDECHFLNRNQVID
LSKIVDVLNIPVLCYGLRTDFRADLFSGSLWLLAWADKLIELKTICYCGR
KANRVLRIDDQGLIIRDGNQILVGGNNRYVSVCRKHFVEQLESPLSLTKR
VYKNR
>BPEN_413 tmk, thymidylate kinase
MDNRFITIEGLDGAGKTTITHRVSKYLNQYGVTDILTTHEPGGTPVSDFL
RVLIKYGGPMNEPINSISELLMIYAARLQLIENVIKPALSKGYWVIGDRF
DLSSQAYQGGGRGIDILLLHALSNKITNTLSPDLTFYLDISPELSISRIN
HRQKLDRIEQEPLSFFDRVRSCYKKLASERKNIITIDATQSLEEVSMSIY
RHLDWWFLRPQE
>BPEN_651 udp, uridine phosphorylase
MTTTHSFHLGLKIGDLQGATLAILPGDPNRVKKIASLMDGAKYIFSNREF
TTWSAKINKETVIVCSTGIGGPSTSIVVEELSQLGIRTFLRVGTSGAIQK
YIKIGDVLIITAAVRCDGASQHFAPLEFPAVADLSCTIALIQAAKNIGIK
SHFGVTVSSDTFYPGQERQDTYSGRVIQKLRGSMEEWKNLGVMSYEMESA
TLLTMCLSQGLRAGVVTGVIVNRTQKEIPNVTLIHHTEYMAMKVAIEGAH
IILSKSNTFLHRYAE
>BPEN_538 upp, uracil phosphoribosyltransferase
MKIVEIKHPLVRHKLGLMRICDISTKRFRELSSELGSLLTYVATDDLEVE
IVTIKGWCGLVKIARIKGKKITVVPILRAGLGMMNGVLEHLPSARISIIG
IYRNEITFEPIPYFHKLVSNINERMAMVLDPMLATGGSIIATIDLLKKFG
CNNIKVLSIVAAPEGIKALEEKHPDIELYLASIDQKINKNGYIIPGFGDA
GDKTFGTK
>BPEN_410 ycfF, putative protein kinase C inhibitor
MKKDNIFMNIIHKKVKTDILYQDELVTAFYDLKPQAPVHVLIVPNILIPT
VNHAKTHDEIILGRLFIVAAKIAEQKNIHSSGYRLIVNCNDHSGQEIYHL
HMHLLGGKPLGPLLQK