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# Bordetella pertussis, Tohama I

>BP2880 conserved hypothetical protein
MRANSNSNPGAATPDDDALLREAIALARANARAGGRPFGALVAKDGVVLA
RGVNRMLADHDPTAHTELLALREAGRALRSARLDGCVVYASGQPCPMCLA
AMRMSGVARAVYAYSNEQAEPYGLSTAALAVELALPPQRQPGFAFEHRPG
AAAPDADLYREWQDGPQAP
>BP1593 conserved hypothetical protein
MSAEILNPNLRRVVLASNNAGKLREFSALFAPLGIELVPQSELGVSEAEE
PHATFVENALAKARHASRHTGLPALADDSGLCVVALGGAPGVHSARYAQQ
PGGARSDAANNALLVRELAAAGDRRAWYVALLALVRTENDPCPLIGEGLW
HGEIVDAPAGEHGFGYDPHFYLPQQGCTAAQLAPEHKNRISHRAQALAQL
LDKLRATGPVDRP
>BP3669 putative chlorohydrolase
MLTQIKGEWVLGFADGNHRMLCDASVVYEGERIVHVGTEFDGVADRVIDA
RGCLVAPGFIDTHVHSGHRALHKLLADGGRPDLFGQPYMDVTIARDGTRI
KGYPNYLSREEAAVDPGIALHAAFTVAELLRNGVTTFVELGGHVMVQEAL
WRECERLGVRGYLGPGYDSGRWAADDQGRLRRVPYPDGGDHLFEEAVAFI
KRVQAAGNDLVNGILVPREVENCSVDILRRTVQAAQELGVPMATHAGYNV
IEFYETVREHRMTPIELLHSVGMLGPRLNIGHANLISDSPRLNYSGGRDL
ALMGEHRVSISHCPINIVRRARVLDSWKKYREAGVNLTIGSDTYPRDMVM
NMRTASYHGKVMSHDLNAASAAEVFEAATLGGARSLGRTDIGRLEPGARA
DVIAINVGRQDVLRYGPIWDPIRSLVECGVGDDVELVVTNGQVRMEQGRI
AGVDLGALRAEAQQFADNVWRDLQDWDPLRRTAQAMCPPSFCPDCM
>BP3658 putative phosphohydrolase
MNKDGTVVLMNELASYASDPSKTRGRRHSEPPPENRTEFQRDRDRIIHSN
AFRRLEYKTQVFVNHEGDLFRTRLTHSLEVAQIARTLARSLRVSEDLTEA
IALAHDLGHTPFGHAGQDELNACMRELAPQAGGFEHNLQSLRVVDELEER
YAEFNGLNLCFETREGILKHCSATHARQLGAVGERFLDRTQPSLEAQLAN
LADEVAYNNHDVDDGLRSGLITLEQLQEVGIFARHYAEVARRYPQLAPRR
ATSETIRRMINTLIVDLTATSLARIRDHAPASADDVRRAPPLAGFSAAVR
READELKKFLFDNLYRHYRVVRMTTKAQRIVRELFQAFLGDPRLLPPDYR
REQPQDQARAISDYIAGMTDRYAIREHRRLFEMG
>BP2269 putative xanthine/uracil family permease
MSNTYFPRWRLADDTVPGAVIAPDERLSWPKNIAMGAQHVVAMFGSTVLA
PLLMGFDPNVAILMSGIGTLIFFLFVGGRVPSYLGSSFAFIGGVVAVTGY
VAPGANANIGVALGAIIACGLVYALIGLVVWAASARGNGARWIEAMMPPV
VTGAVVAVIGLNLAPIAAKGAMGSSGFEASMALMTILCVGGIAVYTRGMV
QRLLILVGLVLACVIYAVCANGLGLGAPMDFAKVAAAPWFGLPSFAAPVF
EPQAMGLIVPVAIILVAENLGHVKAVAAMTGQDLDRYVGRAFVGDGVATM
VSGAVGGTGVTTYAENIGVMAVTRIYSTLVFVVAAVIALVLGFSPKFGAL
IQTIPGPVLGGMSVVVFGLIAIAGARIWVVNQVDFSDNRNLIVAAVTLVL
GAGDFSVKLGDFSMNGIGTATFGAIILYALLGLARRR
>BP3445 putative NUDIX hydrolase
MSAQQSLQYFPAPRRARFCSQCGSPVDHRVPEGDNRARDICDRCGAIHYQ
NPRMVVGTVPVWENRILLCRRAIEPRYDTWTLPAGFMELGESAAQGAERE
TLEESGARIRLGQLYTVIDVPQVEQVHFFYLAEALGPGLDPGPESLEARY
FDEAEIPWDDLSFRTVVTTLRRYLEDRRKGEFPTHHYSLESHR
>BP3254 putative formyltetrahydrofolate deformylase
MQHNDYILTLSCPDRTGIVFRVSGLLFELGCNIRDSQQFGDEETGRFFLR
VHFDLPRAAAESALREQFAALANGYDMQWQIHDAHRKARLLIMVSKQGHC
LNDLLFRVSSGQLRAEVAAIVSNHNDYASLAASYGIPFHHMPVTPDTKAA
QERQVLELVEREQIDLVVLARYMQILSADMCQALAGRAINIHHSFLPSFK
GARPYHQAHARGVKIIGATAHYVTSDLDEGPIIEQDIERVDHTMTAADLT
QVGSDIESLVLSRAVRSHVEHRILLNRSKTVVFR
>BP1437 probable class-I glutamine amidotransferase
MTAALPVLILHTGNPAAALRAAHGSYAEMLRQAAGLDAAGTHVVASYKDE
APRAPGAYRAALITGSPAMVTDRAPWSEAAADWLRQAAGAGLPMFGICYG
HQLLAHALGGVVGDNPAGRELGTLPVELLPAAATDPLLAGLPAAFDAQMM
HEQAVLAAPPGATVLARSAQDAHQILRLAPRIYTAQFHPEFTPGFVAAHL
RHHAALYAAHGLDVEGLARAAGPTPLAASLVRRFLACCA
>BP0530 conserved hypothetical protein
MRLYWRMPTTTPALRPQDLTETAFAPYGWMLGKPLPAGDDVLRFSNPATD
FWQEHVFDTGAGAGRETEVLWVNYRISQPGFDTLEKHLLTQQAIVPLTGA
IVQIVARSAFDGSPDLASLAAFVVPPGQGICMRPGCWHATRISGGEVTCL
MLTRRSTTLDLVRHLHGEPARESEIVAIVPHGLDLPARPTAEGPAPHGR
>BP3154 putative thymidylate synthase
MKQYLDLVQSILDQGAWQENRTGVRTLSLPGAALRFDLQQGFPAVTTKKL
AFKSAIGEMVGFLRATRSAAQFRALGCKVWDQNANENEQWLANPYREGPD
DLGPVYGVQWRHWPAYKLLPSSAGGQVADALARGYRQVAEVDENGAPHVL
LYKAVDQLRQCLDTIRQSPGDRRILFHGWNWAQIEEMALPPCHLLYQFLP
NAGTREISLCLYIRSNDVGLGTPFNLTEGAALLHLVGRLTGYKPRWFSYF
IGDAHVYENHLPMLREQLAREPYPAPQLVLSDRIPDFAVTGKYEPQWLEQ
VEPGDFTLSGYQHHAPLTAPMAV
>BP3776 MttA/Hcf106 family protein
MSDNCIFCKIARGEIPAKKVFEDDEFVAFHDINPAAPVHLLLIPRRHVVS
LQDIAEGDAGWLGRMTVLASRLAAGNGCNPGPDGGFRLMANSGAEGGQEV
PHLHFHILGGPRPWKGRVAPAA
>BP2769 adK, adenylate kinase
MRLILLGPPGAGKGTQAAFLTQHYGIPQISTGDMLRAAVKAGTPLGLEAK
KVMDAGGLVSDDLIIGLVRDRLTQPDCANGYLFDGFPRTIPQADALKSAG
IALDYVVEIEVPESDIIERMSERRVHPASGRSYHVRFNPPKAEGVDDVTG
EPLVQRDDDREETVRHRLNVYQNQTRPLVDYYSSWAQSDAAAAPKYRKIS
GVGSVDEIKSRLSQALQS
>BP1583 amn, putative nucleosidase
MPSDYSIAQLHCPDPVPFEAFDSAVAATDRLIELYRRNTGFVRELFHEVV
GGRELSGRVRAYYPAIRIGVQTYDPIDSRLSYGHVAEPGEYQTTITQPHL
FRDYLIEQIGLLLQNHRVPVEVGESDMPIPLHFAFPDGTYVEGEHIENLR
RPLRDLFDVPDLAVTDDAIVNGSWRGQPGEPRPLAPFTATRVDYSLHRLQ
HYTATAPTHFQNFVLFTNYQFYVDEFCVWARGLMASGGGDYDALIEPGNR
ITRRGDQAPVEAAAVRLPQMPAYHLVRPNHSGITLVNIGVGPSNAKTITD
HIAVLRPHAWLMLGHCAGLRDSQRLGDYVLAHGYVREDHVLDADLPTWVP
VPPLAEVQVALEQAVEEVAGLSGWELKRIMRTGTVATIDNRNWELRDQGE
LVQRFAQSRAIALDMESATIAANGFRFRVPYGTLLCVSDKPLHGELKLPG
MASAFYRRQVNQHLEIGIRALERLREMPPERLQSRKLRTFMETAFQ
>BP0264 apt, adenine phosphoribosyltransferase
MQTDYAELVRRTIRSVPDWPTPGVTFRDITPVLQDPRTFRVLIDLFVYRY
MRQRLDLVAGVDARGFIVGAVLAHELNLGFVPVRKKSKLPYRTVAEEYSL
EYGNAAVEMHTDSVRTGQRVLLVDDLIDTGGTMLAAIKLLQRLGANVVEA
AAIIDLPYLGGSAQITATGTPLYTVCQYQEGD
>BP1452 carA, carbamoyl-phosphate synthase small chain
MADGTIFRGVSIGVPGHTVAEVVFNTSMTGYQEILTDPSYAGQTVMLTYP
HIGNTGVNPEDVEANRVYAAGLVVRDCPARVSNFRATQSLPEYLNAQGIV
AIAGIDTRKLTRILRESGAQGSCILVGEDAERAVELARGFPGMSGQDLAK
VVSIKERADWTQGTWELGSGYTQPAQDRFHVVAYDYGVKSNILRLLADRG
CRVTLVPAQTTAEEAFKLQPDGVFLSNGPGDPEPCDYAVDATRAFLERKL
PVFGICLGHQLMGLALGGKTVKMKTGHHGANHPVQDVQSGRVFITSQNHG
FAVDAATLPANTRVTHISLFDGTLQGFELTDRPAFCFQGHPEASPGPHDI
IVLFDKFISLMAGQK
>BP1453 carB, carbamoyl-phosphate synthase large chain
MPKRTDLKSILIIGAGPIIIGQACEFDYSGAQACKALKAEGYRTILVNSN
PATIMTDPETADVTYIEPITWQAVEKIIEREKPDALLPTMGGQTALNCAL
DLAHHGVLKKHNVELIGANEHAIEKAEDRQKFKQAMTDIGLESAKSGVAH
SMDEAWEVQRRIAADIGTAGFPVVIRPSFTLGGSGGGIAYNAEEFEVICR
RGLEASPTKELLIEESLLGWKEFEMEVVRDKADNCIIVCSIENLDPMGVH
TGDSITVAPAQTLTDKEYQIMRNASIAVLREIGVDTGGSNVQFAVNPQNG
RMIVIEMNPRVSRSSALASKATGFPIAKVAARLAVGYTLDELRNEITGGA
TPASFEPTIDYVVTKVPRFAFEKFPQADARLTTQMKSVGEVMAMGRTFQE
SFQKALRGLEVGVDGLNQKTTDREKLQIELGEPGPERIWYVGDAFAQGFT
LDEVHGLTRIDPWFLAQIKEIVDIELALEQKTLADLDYATLWELKRRGFS
DRRLAFLLDSSESEVRKLRHQLNVRPVYKRVDTCAAEFATNTAYMYSTYE
EECESQPTDRKKIIVLGGGPNRIGQGIEFDYCCVHAALALREDGYETIMV
NCNPETVSTDYDTSDRLYFEPLTLEDVLEIVHKENPVGMIVQYGGQTPLK
LARALEANGVSIIGTSPESIDVAEDRERFQKLLNKLGLRQPPNRTARTEA
EALAHASEIGYPLVVRPSYVLGGRAMEIVHEQQDLERYMREAVKVSNDSP
VLLDRFLNDATEVDVDCLADGQTVFIGGVMEHIEQAGVHSGDSACSLPPY
SLSAEVIAEIKRQTTMMAKALNVSGLMNVQFAIQGGDVYVLEVNPRASRT
VPYVSKATGLQLAKIAARAMAGRTLADQGITREVVPPYFSVKEAVFPFVK
FPGVDTILGPEMKSTGEVMGVGNSFGEAFVKSQLAAGVRLPDSGTVFISV
RNQDKPRAVEVARGLHNLGFKLVATRGTAAEIEAAGIPVQVVNKVTEGRP
HIVDMVKNGEVSLVINTVEERRNAIADSRTIRTQALANRITFFTTIAGAR
AAVEGMQFMRQGLGLQVYPLQELHAGLTAQ
>BP0949 cmk, cytidylate kinase
MAIFASAGAAPVITIDGPTASGKGTIAHRVAKQLGWDVLDSGALYRLTAL
AALRRGLPATDEPAVAAVAQALDVRFDGPHVYLEGRDAGHEIRQEEVGNY
ASRIAAYPGVRQALLERQRAFRQPPGLVADGRDMGAVVFPDASLKIFLVA
DVEARAQRRCKQLIEKGISANLDDLLRDMRERDARDTQRAVAPLAPAADA
HVLDSSGLTIEQTVQAVLDFWCA
>BP1700 cumB, putative zinc-binding hydrolase
MALALEQAQEAARLGEVPVGAVVVDAQGEVLGTGYNRTIIDRDPTAHAEI
VALRAAARRLDNYRLPGVSLYVTLEPCVMCIGAMLHARLARVVYGARDPK
TGACGSVLDVGAVGQLNHHTTITGGVLAEPCGELLRGFFRARRAKESPV
>BP0185 dcd, deoxycytidine triphosphate deaminase
MSIKSDRWIRRAAEAGMIEPFEPGQVRTAGGNRIVSYGTSSYGYDVRCAD
EFKIFTNINSTIVDPKQFDEKSFVDFKGDVCIIPPNSFALARTVEYFRIP
RSVLTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKVYAG
EGCAQMLFLESDEVCETSYRDRGGKYQGQRGVTLPRT
>BP2578 dut, deoxyuridine 5'-triphosphate nucleotidohydrolase
MKSVDLKILDARMREYLPAYATPGSAGLDLRACTEASLVIEPGQTVLVPT
GLAIHIGDPRYAAMILPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSTWN
RGTQPFTLDPMERLAQLVIVPVQQVAFNVVEDFDASERGAGGFGSTGRG
>BP1578 gmK, guanylate kinase
MSAPSGNVFMVVAPSGAGKSSLVRALLDRDPSLVLSISCTTRAPRPGEQD
GREYRFVDQAEFARLRDAQQLLEWAEVHGNFYGTPRDRIDEATRAGHDVL
LEIDWQGARQVKQRYPEAIGIFVLPPSIDELESRLKARGQDAPQVIARRL
LAAGGEIAHAPECEYVIINQEFSVALTELVQIISAARLRFSSQAVRNAQL
FSQLGIPAAH
>BP2624 guaA, GMP synthase [glutamine-hydrolyzing]
MHQRILILDYGSQVTQLIARRVREAGVYSEIHAGDVDDAFVRDQVAQGLK
GIILSGSHASAYEEGSMRVPAAVFDVGVPVLGICYGMQSMAQQLGGTVSF
SDHREFGYAEVRAHGHTKLLDGLADFTTDEGHGMLKVWMSHGDKVTELPP
GFKLMASTASCPIAGMADESRGFYAVQFHPEVTHTVQGKAMLARFVKDIC
GCEGDWNMPDYISEAVARIREQVGSDEVILGLSGGVDSSVAAALIHRAIG
DQLTCVFVDHGLLRLDEGKQVMQTFTENMGVKIVHVDATSQFMGKLTGVA
DPEAKRKIIGREFVEVFQDEAGKLQGAKWLAQGTIYPDVIESAGAKTGKA
TSIKSHHNVGGLPDTLNLQLLEPLRELFKDEVRELGVALGLPPQMVYRHP
FPGPGLGVRILGEVKHEYAELLRRADAIFIEELRNAKDPASGLTWYELTS
QAFAVFLPVKSVGVMGDGRTYEYVVALRAVQTFDFMTADWAPLPHPLLAR
VSSRIINEVRGINRVVYDVSSKPPATIEWE
>BP2202 ndk, nucleoside diphosphate kinase
MSIERTLSIIKPDAVAKNVVGQIVARFEQAGLKVIAARMQQLSRTDAERF
YAVHKERPFFKDLVDFMVSGPVFVQVLEGESAIQKNRDLMGATDPKKAAP
GTIRADFADSIDANAVHGSDAPETAAVEVAFFFPEINIHSR
>BP2983 nrdA, ribonucleoside-diphosphate reductase alpha chain
MQTTIASVTRPTAVPPAQSETSTDPNSGQWASYNIIRRNGSVVGFEPSKI
AIAMTKAFLAVNGGQGAASARVRELVEQLTAQAVSALVRNRPAGGTFHIE
DVQDQVELALMRSGEHDVARAYVLYRERRAQERAAAAEVLEKSSPAAAQE
PTLSVVDNGVRRPLDLAALRATIEAAGEGLTQYTDTEAILKETVKNLYDG
VPVDEVFKSAILAARALVEKDPAYSQVTARLLLHTIRKEVLGEEVSQADM
ATRYAEYFPAFIQRGIEGGLLDAKLAEYDLERVAKALDGRRDLQFGYLGL
QTLYDRYFLHVRGTRIELPQVFFMRVAMGLALREADREARAIEFYEILSS
FDFMSSTPTLFNSGTLHSQLSSCYLTTVSDDLEGIYDAIKENALLAKYAG
GLGNDWTPVRALRSHIKGTNGESQGVVPFLKVVNDTAVAVNQGGKRKGAV
CTYLETWHLDIEEFLELRKNTGDERRRTHDMNTANWIPDLFMKRVMENGE
WTLFSPSDCPDLHDKYGKAFEQAYAGYEAKVASGELKLFKKMPAVSLWRK
MLSMLFETGHPWITFKDPCNIRSPQQHVGVVHSSNLCTEITLNTNATEIA
VCNLGSVNLVAHMKPNANGGYELNHDKLKRTIGVAMRMLDNVIDINYYAV
DKARNSNERHRPVGMGIMGFQDCLHVMRVPYASQDAIDFADRSMEAVCYH
AYWASSELAQERGRYQSYEGSLWSRGILPQDTLAMLREERGGNVDVDDSS
SLDWDTLRSRIKEHGMRNSNCIAIAPTATISNIIGASACIEPTFQNLYVK
SNLSGEFTVVNDYLVRDLKKLGLWDEVMVADLKYFDGSLSRIDRVPSELR
KLYATAFEVEPSWLVECASRRQKWIDQAQSLNIYMSGASGKKLDDTYKLA
WQRGLKTTYYLRTLGATSAEKSTGRGGELNAVSAGDHGAGSAVSAAPVLP
EPEIVGAVCTMRPGDPGFEECEACQ
>BP2984 nrdB, ribonucleoside-diphosphate reductase beta chain
MLNWEEENIATKPATSPAPAGGREAAPAVRAATGVFGDAALPTPTAPQHA
ASLGASDATAGRVKVADKRIINGETDVNQLVPFKYKWAWEKYLATCANHW
MPQEINMSRDIALWKNPNGLTEDERRIVKRNLGFFVTADSLAANNIVLGT
YRHITAPECRQFLLRQAFEEAIHTHAYQYIVESLDLDEAEIFNAYNEVPS
IRAKDEFLIPFIDAIADPNFHTGTPEADQKLLKSLIVFACLMEGLFFYVG
FTQILALGRQNKMTGAAEQYMYILRDESMHCNFGIDLINTIKLENPHLWT
PEFREEIRELFRKAVELEYAYAEDTMPRGVLGLNAPMFKSYLRFIANRRC
QQIGIEPLFPQEENPFPWMAEMIDLKKERNFFETRVIEYQTGGTLSWE
>BP1073 ppx, exopolyphosphatase
MDHLLAAVDLGSNSFRLSIGRVVQQDGTAQIYQIDRLKETVRLAAGLDQD
KNLGEDALARALAVLERFGERLRSFHPSRVRAVATNTFRVARNTRDFLPR
AERALGFPIEVIAGREEARLIFSGVAHSLPPSLNRRLVIDIGGGSTEVII
GKGVEPNLMSSLYMGCVSFSRQFFGDGVVDSHQMKQAELAARREIEVISK
QYRKTGWKEAYGSSGTAKALYAILTECGFSTRGITRAGLAKLKDRIIRSG
RVIPAELPGIKLERADVLPGGLAIMSALFDELNIDVMHTGDGALRLGVLY
DLLGRDDEHDKRHESVQQFMKRYHVDANQARRVRQAALALFDVLLPDGDG
HERAELRLALGWAADLHEVGLSIAHNAYHKHTAYVLEHADMPGFSNDEQE
LLALLALGHHGKLSKLESLVANRSQWIAILCLRLAALLFRRREDITPLPL
AVSIKGTSIVVRAQQAWLNRHPLSDFTLRAEDGEWSKVGFSFELLET
>BP3125 prsA, ribose-phosphate pyrophosphokinase
MANDSFMIFTGTANTRLAVDVVNHLDMSLGKMTVGRYSDGEVMVEINENV
RGKDVFVLQPTCAPTNDNLMEIMVMVDALRRASAGRITAAIPYFGYARQD
RRPRSARVAISAKVVANMLQVAGVDRVLTMDLHADQIQGFFDIPVDNIYA
GPILLGDIWRRNFSNLVVVSPDIGGVVRARALAKQLEADLAIIDKRRPRA
NVSEVMNIIGEVDGRTCIIMDDMVDTAGTLCKAAQALKDRGAGAVYAYCT
HPVLSGGAIERIETSSLDELVVTDTIPLSEQAQACGKIRQLSCAALLGET
ILRISNAESVSSLFAD
>BP2188 purA, adenylosuccinate synthetase
MIRKMSKNVVVIGTQWGDEGKGKIVDWLAESVQGVVRFQGGHNAGHTLWI
NGKKTILRLIPSGIMHDGVTCFIGNGVVLSPEALLREIEELEAAGLDVRS
RLQVSEICTLILPYHVAVDKAREARKGEGKIGTTGRGIGPAYEDKVARRA
LRVQDLFNPALFDEKLAEVLDYHNFVLTQYLGAEPVSANEVRDQAMALAP
ALAPMVRDVSSNLFALQQEGKNLLFEGAQGALLDVDHGTYPFVTSSNCVA
GAASAGAGVGPQALQYVLGITKAYTTRVGSGPFPTELVDEIGARLATIGK
EFGSVTGRPRRCGWLDGAALKRSVRLNGISGLCITKLDVLDGLETIQLGV
GYRVNGEFRDVLPYGAHAVAQAQAVLEELPGWTESTVGITEYSKLPVNAR
RYLERVAEVCGVPIDLVSTGPDRNKTIVLRHPFKG
>BP2890 purB, adenylosuccinate lyase
MQIADQLTQLNALSPLDGRYASRAGALRGLLSEAGFMAHRVEVEVAWLVA
LSDAGLPELPAFPAAARERLAALVRNFSEADAARIKDIERVTNHDVKAVE
YWLKEQVADDAELARAAEFIHFACTSEDINNTSHALMLTRARAEVVVPQL
NQVLAKLNELARTHADQPMLSRTHGQPASPTTLGKEFANVAARLQRAVAA
IEAVEPLAKLNGATGNYNAHLSAYPEIDWPAFSRNVLAGLGLIQNRHTIQ
IEPHDWMAALFDAVARANVIVLDLDRDIWGYVALGYFKQRLKEGEVGSST
MPHKVNPIDFENSEGNLGLANAVLRHLSEKLPVSRWQRDLTDSTVLRNLG
VGLGYALVAWDACLRGLNKLEVNAAAIDADIDACWEVLAEPVQTVMRRYG
LPQPYEQLKTLTRGKGITEEALREFIGGLALPDEPKARLLAMTPRSYIGL
AAQLARAV
>BP1521 purC, phosphoribosylaminoimidazole-succinocarboxamidesynthase
MTSALHESSIKSLPLLGRGKVRDMYAVGDDKLLIVASDRISAFDVILDDP
IPGKGQVLTELTDFWLRKLAHILPNHSTGIQPEDVVAPDEVDQVRGRAVV
VKRLKPILVEAVARGYLIGSGWKDYQASGSVCGIALPAGLQQASQLPEPI
FTPAAKAEFGMHDENVDFAHVVKEVGQEMAERIRDVTLRLYGEAARFAAT
KGIIIADTKFEFGLDDNGTLHLMDEVLTPDSSRFWPADGYRVGISPPSFD
KQFVRDWLETQPWDKTPPAPRLPRDVLEKTAAKYREALDRLLA
>BP2309 purD, phosphoribosylamine--glycine ligase
MSGNLQKPRNMKLLVIGSGGREHALAWRLARSPRVHKVYVAPGNGGTAQG
EQLENVPLTSAEELADFVQREGVSLTVVGPEAPLAAGVVDVFRARGLKIF
GPTKAAAQLESSKDYAKAFMVRHAIPTARYETFTDPAQAHAYVDQHGAPI
VIKADGLAAGKGVVVAMTLDEAHGAIDAMLGDGSLGEAGARVVIEEFLTG
EEASFIVMCDGRHVLALATSQDHKRLKDGDAGPNTGGMGAYSPAPVVTPE
LHHRIMREIILPTVQGMARDGIPYTGFLYAGLMIAAGDDPDRPIKTLEYN
CRMGDPETQPIMMRVKSDLLDAFEHAVDGTLDQADIVWDRRTALGVVLAA
HNYPATPRTGDVIAGLPAATEDCVVFHAATALDGDATKTTGGRVLCVTAL
GDSVRIARDRAYEAVDAIHFDGRQYRTDIGWRALKPSQQKAPKPTA
>BP1526 purE, phosphoribosylaminoimidazole carboxylase catalytic subunit
MGVIMGSSSDWEVMKHAVAMLQDFGVAHEARVISAHRMPQDMAEYGAAAR
ARGLRAIIAGAGGAAHLPGMMAALTEVPVFGVPVPSRYLRGEDSLLSIVQ
MPKGVPVATFAIGEAGAANAALHAIATLATTDDALHARLVAFRARQTDAA
RAMKVPPEA
>BP1415 purF, amidophosphoribosyltransferase
MCGIVGVIGRGPVNQLLYDSLLLLQHRGQDAAGIATLQGNHFNMYKAHGL
VRDVFRTRNMRALPGTSGVGQVRYPTAGSSASEEEAQPFYVNAPFGIMFA
HNGNLTNWRELRESLYRVDRRHINTNSDSEVLLNVLAHELQSAASGVSLD
DDTIFRAVSAVHQRVKGAYAVVAQISGYGMLAFRDPHGIRPLCIGRQETE
EGVEWMAASESVALEGSGFAFVRDVEPGEAIFVDLDGRMTSRQCADNAQL
VPCIFEYVYFARPDSLIDGVSVYDARLRMGEYLADKVARSMRLGDIDVVM
PIPDSSRPAAMQLAHRLGLDYREGLIKNRYVGRTFIMPGQAVRRKSVRQK
LNAIGMEFKGKNVLLVDDSIVRGTTSREIVDMARAAGANKVYFASAAPPV
RFPNVYGIDMPTQKELIATGRTDDEIARTIGADALIYQDLQDMQQAVRDI
NPRLSRFEASCFDGEYVTGDITAEYLARLGQSRDSSAGDEEAGGLQFNMG
YAANDA
>BP3416 purH, bifunctional purine biosynthesis protein
MKIETALLSVSDKTGIVEFARALTARGVRLLSTGGTARLLSEAGLAVTEV
AQHTGSPEILEGRVKTLHPKIHGGLLARRDSAEHMDTIAACGIDRIDMLV
VNLYPFRETVAKPDCTFADAIENIDIGGPAMLRAAAKNHGTDAGGVTVVI
DPADYSRVLAQMDQGGSTSYALRLELAAKVYSHTAAYDGAIAAYLTSLAE
AAPAQDAVPARNEWPGTLTIQVRQEQALRYGENPHQTAAFYVDAQRPAGL
LGNYRQLQGKELSYNNIADADAAWECVRSFDSTACVIVKHANPCGVAIGD
GTLHVYQQAFKTDPTSAFGGIIAFNRPVDAATAEAVSGQFLEVLLAPAYD
GAALAILAAKKNVRVLEVPAGPGQNAFDIKRVGGGWLVQSPDAYNVPRDA
LKVVSKRQPTEQEMNDLAFAWKVAKYVKSNAIVFVGGGMTLGVGAGQMSR
IDSARIASIKAENAGLTLRGSAVASDAFFPFRDGLDVVVAAGATCVIQPG
GSVRDDEVIAAADEHGIAMVLTGTRHFRH
>BP1527 purK, phosphoribosylaminoimidazole carboxylase ATPase subunit
MTQSSTFDPIASGDWLGLLGGGQLGRMFCHAAQSLGYKVAVLDPADECPA
GMVADLHIQAAYDDADGLARLAGRCRAVTTEFENVPADSLRALAARCRVS
PAADAVAVVQDRIAEKTFIAGQGIEVAPHAAICARDDLLAAPQALFPGIL
KVARLGYDGKGQARIASREEALAAFDEFGGVPCVLEALLPLDYEISVVIA
RGFDGASMVFPIARNVHRDGILAVSSVTPGAADASHAARQVQATQAAQAI
AQGLGYHGVLCVEFFVLGDGRLVVNEIAPRPHNSGHYTIDACVTSQFEQQ
ARVMAGLPLGSADLLAPAVMLNILGDVWFEPGAHAPREPDWSAALAVPSA
KLHLYGKREARRGRKMGHVTIVAATPEQARDDAARVACALGMAAPL
>BP2668 purL, phosphoribosylformylglycinamidine synthase
MSLVQHLPGSSVLSAFRRERLLAQLKKAGLPVADISARYEHFIHTDSALP
AEQQARLAQLLDYGTPAAETPAKSLELLVIPRLGTMSPWASKATDIAHNC
GLDAVRRIERGVRYALTPERGLLGAKSFDADMLARAADCLHDRMTETVVD
GAFDGQALFETLAGKPMRTVAVQAEGRAALEQANVALGLALSEDEIDYLA
QSFGDLGRDPTDVELMMFAQANSEHCRHKIFNAQWVIDGQEQSNTLFGMI
RATHKAQPAGTVVAYSDNAAIMEGGPAQRFQAGVPGVAGEGAQAARYVRR
DTTVHTLMKVETHNHPTAIAPFPGAATGAGGEIRDEGATGRGSKPKAGLT
GFTVSHLRFDDALQPWENDHHGLPERIASPLSIMIDGPIGGAAFNNEFGR
SNLLGYFRAFEQTAGGTRWGYHKPIMIAGGLGSIDAGLTHKEVIPPGALL
IQLGGPGLRIGMGGGAASSISMGSNSAELDFDSVQRGNPELERRAQEVID
RCWQQGERNPIVAIHDVGAGGLSNAFPELVNDAGRGAIFDLKRVPLEESG
MSPAEIWSNESQERYVLSILPQDLERFDAIARRERCPYAVVGVATEERQL
RVVDGEGLPGLDTIRAQGENEVRPVDVPIDVILGKPPRMTRDVQRLPGVS
EPLDLAGLDLTEAAYRVLRHPTVANKSFLITIGDRTVGGLSSRDQMVGPW
QVPVADCAVTLADFEGTRGEAMSMGERTPLAMLDAPASGRMAVAEALTNL
AAADVARLEDIKLSANWMAACGVPGQDAALYDTVSAVSELCQSVGLSIPV
GKDSLSMKTSWDEVGEQRQVVAPVSLVVTAFAPVGDVRASLTPQLRTDAG
DTVLILIDLGRGRHRMAGSILAQAYNQVGETVPDIDAPQDLRAFFVTIRT
LAEAGTILAYHDRSDGGLFATLAEMAFAGRTGVSVNLDMLTFDPQSADWG
DYKIRPEQVAVQREELTLKALFSEEAGAVIQVPASQRDAVMQVLRGAGLS
AHSHVIGGLNGADEVEFYRDGRKVWSQPRADLGRAWSEVSYRIMARRDNP
ACAQAELDVWNDAKDPGLAPRVAFDPQEDVAAPFIGTGKRPRVAILREQG
CNSQVEMGWAFDTAGFEAIDVHMTDLLSGRIDLAGMQGLVAVGGFSYGDV
LGAGEGWARTIRYNDKLSDQFAAYFARPDTFALGVCNGCQMMAALAPMIP
GAEHWPRFTRNQSEKYEARLSLVEVTASPSIFFAGMEGARIPVAVAHGEG
YADFSQQGDAARALMAVRYIDNHGAATETYPFNPNGSPGGLTAVTTADGR
FTVMMPHPERVTRNVMMSWAPAQWGERDAGGAFSPWMRIFRNARVWLK
>BP0242 purM, phosphoribosylformylglycinamidine cyclo-ligase
MTNQHSAPLTYRDAGVDIDAGDALVDRIKPLAARTMRPGVLAGIGGFGAL
FEVPKKFREPVLVSGTDGVGTKLRLAFDWNRHDTVGIDLVAMSVNDILVQ
GAEPLYFLDYFACGKLSVDTAAAVVGGIARGCELAGCALIGGETAEMPGM
YPDGEYDLAGFAVGAVDKSAIIDGKSIQPGDVVLGLASSGAHSNGYSLVR
KILERAGARPDQDFHGQPLVDVVMAPTRIYVKQVLAALDRHGPAIKGLAH
ITGGGLLDNVPRILQPGMAAQLQRDGWEMPKLFQWLQQQGSVADAEMHRV
FNCGIGMVLVVAADQADAVAATLREQGEIVNRIGEIVPQQDGMAQTVVV
>BP0702 purT, phosphoribosylglycinamide formyltransferase 2
MSTFPAPVLGTPLSPTATRVMLLGAGELGKEVVIALQRLGVEVIAVDRYA
DAPGHQVAHRAHVVSMTDPQALRQVIEQERPHVVVPEIEAIATDLLVALE
DEGAVHVTPTARAAHLTMNREGIRRLAAETLGLPTSPYRFVDTEQALREA
IDGGIGYPCVIKPVMSSSGKGQSIIRSADDIAAAWRYAQEGGRVGAGRVI
VEGFIEFDYEITLLTVRARGADGQIVTQFCEPIGHRQVDGDYVESWQPHP
MSPVALQRSREIALAVTGDLGGLGIFGVELFVAGDQVWFSEVSPRPHDTG
MVTLISQVQNEFELHARALLGLPVDTRLRQPGASSVIYGGVDARGVAFEG
VAQALAEPGTDIRLFGKPESYAKRRMGVGLAVADDVDQARAKAARVSQAV
RVRA
>BP2514 purU, putative formyltetrahydrofolate deformylase
MKQYVLLLKCLDRPGIVHEISGGLFQEGCNIEESAQFSESGTAVFYMRVR
FSAPDRACVQKIATALKRLYNGDEAGLAIHDMDKRSRVLILVSKHGHCLN
DLLFRQRSGLLNMDVAGVVSNHPDFRELAASYDIPFHHFPVTPQTRAEQE
GRILDLVASTQSDLVVLARYMQILSDRASNALSGRAINIHHSFLPGFKGA
RPYYQAYDRGVKLIGATAHYVTSELDEGPIIEQDVARVSHSLEPQALTDV
GRDVECMTLARAVKWHTEHRIILNGRKTIVFA
>BP0321 pyrB, aspartate carbamoyltransferase
MLNPQLNRHGELIHLLSTEGLPRRIIEQILDLAATFVPAPGQEFPKLPLL
HGKSVFNLFFENSTRTRTTFEIAAKRLSADVVNLNIAASSTSKGESLLDT
IANLSAMQADLFVVRHGASGAPYLIAQHVAPHVHVINAGDGRHAHPTQAL
LDMYTIRHHKGDFNQLTVAIVGDVLHSRVARSDIHALTTLGVPEVRVVAP
ATLLPEGLAQMGVRVCTDMEEGLRDADVVIMLRLQNERMRGALLPSAHEY
FKHYGLTQARLALARPDAIVMHPGPMNRGVEIASEVADSGQAVILDQVTF
GIAVRMAAMSLVAGVRP
>BP2562 pyrB, aspartate transcarbamoylase
MSISQQAFLRDAMRRLNLTRDVFAGRIGVKRRALDTWLLPEGSQEFRAMP
EVVERFVSEIVQNRDLLEKYTQSGQVGPLRDRIAVEGRHQLLSVDQFTRE
SVEDLFRVADMMQPIARRQKVSRVLEGAVLGNLFFEASTRTRVSFGAAFC
RLGGSVCDTTGFTFSSMAKGESIYDTSRVMSGYVDAMVIRHPEQGSVAEF
AEATNIPVVNGGDGPGEHPSQALLDLYTILTEFSRLGKLLDGAHIAMVGD
LKYGRTVHSLIKLLALYKGVKFTLISPQGLEMPGYIVEQASRNGNVIEQK
STLAEGLAGADVIYATRVQKERFANEEAGEGYTADFQVSRAIIDAYCGPD
TIVMHPLPRDSRPGSNDLSTDLNHDPRLAIFRQTDNGIPIRMAIFAVLLG
VEGLVQHSMRDVTWQHPSHIGPDDSVFHGLD
>BP0322 pyrC, dihydroorotase
MTVRTVRIAGGRLIDPASGADARADLYLADGRIAAIGQAPAGFQAQQHID
ARGLAVLPGLVDLSARVHGAGLAPLACEMQAALAGGVTRLVVPPDTDPPL
DEPGRVEMLRHRAHQAGQAQLHPLGALTEGLRGERLSEMAALAEAGCVAF
SQAGLPVADTRVLWRAMQYARTFGLALWLRPLDPWMGRDGVAAAGAYASR
LGLAEVPVQAETLALHTIFELQRATGARVHLMRLSSAAGVALVRAARREG
LPLTCDVAAHQIHLTDVDIGFFDSRFRLDPPLRGQRDRDAIVAGLADDTI
DAICSDHRPVGDTGKLLPFAEAEAGASGLELLLSLTLKWAQRERVPLARA
LALVTSAPAAILRAATAAPPPCGELAAGAPADLCLVDLDAD
>BP3035 pyrC, dihydroorotase
MRPASMSNQHATELTITRPDDWHLHLRDGSALEAVVLDTARQFARAIVMP
NLRPPVTTTEQALVYRARIEAALRKAGGDTAAFTPLMTLYLTDNTPAEEI
VRAHESGQVAAVKLYPAGATTNSDAGVTDLLGKCGAALAALERCGMPLLV
HGEVTDPAIDVFDREAVFIERVMQPLRRAYPGLKVVFEHITTREGAHYVR
DAEGPTAATITPQHMLYNRNAIFTGGVRPHWYCLPILKREVHRQALVEAA
TSGSPRFFLGTDSAPHARGLKEHACGCAGCYTALHAMELYATAFDAVGRL
DRLEGFASFHGPDFYGLPRNTGTLTLRREAYEIPAEVAFGDTTLVPLSGG
ESLGWRALA
>BP3442 pyrD, dihydroorotate dehydrogenase
MSILFHAYPLARPALFAMDAETAHEVTLAQLQRAYDCGLTRKLLHAQPEA
PATLMGLSLRNPVGLAAGLDKNGAHIDALGNLGFGFVEVGTVTPRAQPGN
PKPRMFRLPRANALINRLGFNNQGLDAFIANVQRSQWRSQGRILGLNIGK
NADTPIERAAEDYLIGLAGVYPHADYVTVNISSPNTKNLRALQGGDELSA
LLGQLQERRLALADQHQRHVPLAVKIAPDLSDDQIDAIAEILPRHGIDGV
IATNTTLARDAVQGLPHAEEAGGVSGAPVHELSLRVIERLRSRLGDAVAI
IGVGGILSGRQASEKMAAGAQAVQLYTGLIYRGPALVGECVRALAQGSR
>BP0370 pyrE, orotate phosphoribosyltransferase
MSASASTAADFVRFALDEGVLRFGSFKVKSGRISPYFFNAGLFNSGRSVG
TLAGFYAQALIDSGVAFDMLFGPAYKGIPLATATSVALAGHGAMAGRDVP
FAFNRKEAKDHGEGGTLVGAPLTGKVVIIDDVITAGTSVRESVEIIRAAG
AEPAAVLIALDRMERAGPDDALSPHSAVQDVARTYGIPVVSIASLADIMT
LLQDDAQFAEHRAAVQAYRSKYGV
>BP3490 pyrF, putative orotidine 5'-phosphate decarboxylase
MTFLKKLEHAWSASQSLLQVGLDPDPKRFPRELEGKPDAIFQFCRDIVDA
TAPYACSFKPQIAYFAAHRAEDQLEALCQHIRAQHPDLPIVLDAKRGDIG
STAENYAREAFERYQAHALTVSPYMGLDSVEPYLAWGDRGVIVLCRTSNP
GGSDLQFLKMADGQPLYLHVAGLVADKWNANGQCGLVVGATFPNELAAVR
QRIGDAVPLLVPGIGAQGGDINATVQAGANSAGAGMMINSSRAILYASTG
EDWRQAAGEAARGLRDAINAVRT
>BP2389 pyrG, CTP synthase
MTKYVFVTGGVVSSLGKGIAAASLAAILESRGLQVTLLKLDPYINVDPGT
MSPFQHGEVFVTEDGAETDLDLGHYERFISARMRKVNNFTTGQIYESVLR
KERRGDYLGKTVQVIPHITNEIQDFVARGAEAAWNGATDVAIVEIGGTVG
DIESLPFLEAARQMSLRMGRNNAAFVHLTLVPYIASAGELKTKPTQHSVQ
KLREIGIYPNVLLCRADRRIPDDERAKISMFSNVPLDAVISVWDVDSIYK
IPAMLHKQGVDNIVCEALGLTPPPADLSMWDNLVDALEHPQDSVTIGMVG
KYVDLTESYKSLSEALVHAGIHTRSKVNIEYIDSEDIETRGTDQLKHLDA
ILVPGGFGKRGTEGKIAAIRYARENGVPYLGICLGMQLAVIEFARHVAGL
GGANSTEFDPAAPHPVVALITEWMDREGRVERRDNSSDLGGTMRKGAQRC
PIRPGTRAQSIYGDDVNERHRHRYEVNNVYVPRLEDAGMVISARTPTENL
PEMMELPSHPWFVGVQFHPEFTSTPRDGHPLFSSYIRAALEHKAQRAKEA
>BP1421 pyrH, uridylate kinase
MSSRSYKRVLLKLSGEALMGEDAFGINRSTIVRMTDEIAEVAALGVELAI
VIGGGNIFRGVAPGAQGMDRATADYMGMMATIMNALALQDALKHKGVDTR
VQSALNIDQVVEPYIRPKALRYLEEGKVVIFAAGTGNPFFTTDTAAALRG
AEIGAEIVLKATKVDGIYSADPNKDPTATRYARISFDEVIVRRLEVMDAT
AFALCRDQKLPIKVFSINKSGALKRAVSGEDEGTLVHV
>BP1847 tmk, thymidylate kinase
MTPRGRFITLEGVDGAGKSTHTAWMVQALRDLGLTVLATREPGGTPVGEK
LRELLLSEPMALETETLLMFAARCEHVREVIAPALARGEWVVCDRFTDAS
YAYQGGGRQLGAARVAALEQWVHPDLQPDRTWLFDVPLDVARARLARSRQ
LDRFEREEDAFFERTRAAYHERARSSDGRIRIIDSSRPLEVVRAQLDSEV
RELVAQAA
>BP1052 upp, uracil phosphoribosyltransferase
MPVHEIRHPLIRHKLGIMRRADLSTKSFRELSQEVAALLTYEATKDMPLA
PASVEGWCGTVEVDKITGKKVTVVPILRAGIGMLDGVLSLIPGAKVSVVG
VARNEETLQAHTYLERLVGELDQRLALIVDPMLATGGSMVAAIDMLKRAG
CREIRALTLVSAPEGIDAVLKAHPDVQIYTASIDQGLNENGYIMPGLGDA
GDRIFGTTQKHAE