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# Staphylococcus aureus subsp. aureus Mu50, Mu50

>SAV0023 probable 5'-nucleotidase precursor
MKALLLKTSVWLVLLFSVMGLWQVSNAAEQYTPIKAHVVTTIDKATTDKQ
QVTPTKEAAHQFGEEAATNVSASAQGTADEINNKVTSNAFSNKPSTAVST
KVNETHDVDTQQASTQKPTQSATFTLSNAKTASLSPRMFAANVPQTTTHK
ILHTNDIHGRLAEEKGRVIGMAKLKTIKEQEKPDLMLDAGDAFQGLPLSN
QSKGEEMAKAMNAVGYDAMAVGNHEFDFGYDQLKKLEGMLDFPMLSTNVY
KDGKRAFKPSTIVTKNSIRYGIIGVTTPETKTKTRPEGIKGVEFRDPLQS
VTAEMMRIYKDVDTFVVISHLGIDPSTQETWRGDYLVKQLSQNPQLKKRI
TVIDGHSHTVLQNGQIYNNDALAQTGTALANIGKVTFNYRNGEVSNIKPS
LINVKDVENVTPNKALAEQINQADQTFRAQTAEVIIPNNTIDFKGERDDV
RTRETNLGNAIADAMEAYGVKNFSKKTDFAVTNGGGIRASIAKGKVTRYD
LISVLPFGNTIAQIDVKGSDVWTAFEHSLGAPTTQKDGKTVLTANGGLLH
ISDSIRVYYDMNKPSGKRINAIQILNKETGKFENIDLKRVYHVTMNDFTA
SGGDGYSMFGGPREEGISLDQVLASYLKTANIAKYDTTEPQRMLLGKPAV
SEQPAKGQQGSKGSESGKDVQPIGDDKAMNPAKQPATGKVVLLPTHRGTV
SSGTEGSGRTLEGATVSSKSGNQLVRMSVPKGSAHEKQLPKTGTNQSSSP
AAMFVLVAGIGLIATVRRRKAS
>SAV2589 dihydroorotate dehydrogenase
MYKLIKPFLFKIEPEKAHGLTIDALKTLQKFPVLFPVVDKLFTYKNPTLS
QTIQGNTYDNPIGLAAGFDKSCEVPKALEHLGFGALELGGITPKPQPGNP
QPRMFRLLEDDALINRMGFNNIGMNKALSHLRKNAYQVPVGINVGVNKMT
PYEARYQDYIKVIDTFKHDVSFFTVNISSPNTENLQNFHDKDEFSMLCQA
LTTFKKQHDVTVPIYLKLTSDMDFDGLKALLPAITETFDGIILANTTRQR
DGLTSANKVEEGGLSGRPLFERNLKLIKYAYQQTNGEFLIIGTGGVFSTE
DAIKMMRHGASLIQIYSSLVIEGPGLTKKMNKGIARYLKDHHFDNVSDII
GLDA
>SAV2137 deoxyribose-phosphate aldolase
MNSAKLIDHTLLKPESTRTQIDQIIDEAKAYHFKSVCVNPTHVKYAAERL
ADSEVLVCTVIGFPLGASTTATKAFETEDAIQNGADEIDMVINIGALKDG
RFDDVQQDIEAVVKAAKGHTVKVIIETVLLDHDEIVKASELTKVAGADFV
KTSTGFAGGGATAEDVKLMKDTVGADVEVKASGGVRNLEDFNKMVEAGAT
RIGASAGVQIMQGLEADSDY
>SAV0145 2'-3'-cyclic-nucleotide 2'-phosphodiesterase
MSNIAFYVVSDVHGYIFPTDFTSRNQYQPMGLLLANHVIEQDRRQYDQSF
KIDNGDFLQGSPFCNYLIAHSGSSQPLVDFYNQMAFDFGTLGNHEFNYGL
PYLKDTLRRLNYPVLCANIYENDSTLTDNGVQYFQVGDQTVGVIGLTTQF
IPHWEQPEHIQSLTFHSAFETLQQHLPEMKRHADIIVVCYHGGFEKDLEN
GTPTEVLTGENEGYAMLEAFSKDIDIFITGHQHRQIAERFKQTAVIQPGT
RGTTVGKVVLSTDEYENVSVESCELLPVIDDSTFTIDEDDHHLRKQLEDW
LDYEITTLPYDMTINHAFEARVAPHPFTNFMNYALLEKSDADVACTALFD
SASGFKQVVTMRDVINNYPFPNTFKVLAVSGAKLKEAIERSAEYFDVQND
EVSVSADFLGPKPQHFNYDIYGGVSYTIHVGRPKGQRVSNMMIQGHAVDL
KQTYTICVNNYRAVGGGQYDMFIDAPVVKDIQVEGAQLLIDFLSNNNLMR
IPQVVDFKVEK
>SAV0313 probable pyrimidine nucleoside transport protein
MNILFAITGIAFALFVAFLFSFDRKNIDFKKTLIMIFIQVLIVLFMMNTT
IGLTILTALGSFFEGLINVSKAGINFVFGDIQNKNGFTFFLNVLLPLVFI
SVLIGIFNYIKVLPFIIKYVGIAINKITRMGRLESYFAISTAMFGQPEVY
LTIKDIIPRLSRAKLYTIATSGMSAVSMAMLGSYMQMIEPKFVVTAVMLN
IFSALIIASVINPYKSDDSDVEIDNLTKSTETKSVNGKTGKPKKVAFFQM
IGDSAMDGFKIAVVVAVMLLAFISLMEAINIMFGSVGLNFKQLIGYVFAP
IAFLMGIPWSEAVPAGSLMATKLITNEFVAMLDFKNVLGDVSARTQGIIS
VYLVSFANFGTVGIIVGSIKGISDKQGEKVSSFAMRLLLGSTLASIISGS
IIGLVL
>SAV1152 conserved hypothetical protein
MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAI
LKSEAAAKALNKTVIADDSGLEVFALNGEPGIYSARYAGENKSDEANIEK
LLNKLGNTTDRRAQFVCVISMSGPDMETKVFKGTVSGEIADGKYGENGFG
YDPIFYVPKLDKTMAQLSKEQKGQISHRRNAINLLQAFLEGEKNV
>SAV0645 pyrimidine nucleoside transporter
MFLLINIIGLIVFLGIAVLFSRDRKNIQWQSIGILVVLNLFLAWFFIYFD
WGQKAVRGAANGIAWVVQSAHAGTGFAFASLTNVKMMDMAVAALFPILLI
VPLFDILMYFNILPKIIGGIGWLLAKVTRQPKFESFFGIEMMFLGNTEAL
AVSSEQLKRMNEMRVLTIAMMSMSSVSGAIVGAYVQMVPGELVLTAIPLN
IVNAIIVSCLLNPVSVEEKEDIIYSLKNNEVERQPFFSFLGDSVLAAGKL
VLIIIAFVISFVALADLFDRFINLITGLIAGWIGIKGSFGLNQILGVFMY
PFALLLGLPYDEAWLVAQQMAKKIVTNEFVVMGEISKDIASYTPHHRAVI
TTFLISFANFSTIGMIIGTLKGIVDKKTSDFVSKYVPMMLLSGILVSLLT
AAFVGLFAW
>SAV0556 deoxypurine kinase
MNNYGIPQNAIITIAGTVGVGKSTLTQALADKLNFKTSFENVEHNPYLDK
FYSDFERWSFHLQIYFLAERFKEQKRMFEYGGGFVQDRSIYEDVDIFAKM
HEEEGTMSKEDFKTYSDLFNAMVMTPYFPKPDVMIYLECNYDEVIDRIIE
RGREMEINTDPEYWKKLFKRYDDWINSFNACPVVRININEYDIHKDPESL
NPMIDKIARIIQTYRQVDTR
>SAV0510 hypoxanthine-guanine phosphoribosyltransferase homologue
MHNDLKEVLLTEEDIQNICKELGAQLTKDYQGKPLVCVGILKGSAMFMSD
LIKRIDTHLSIDFMDVSSYHGGTESTGEVQIIKDLGSSIENKDVLIIEDI
LETGTTLKSITELLQSRKVNSLEIVTLLDKPNRRKADIEAKYVGKKIPDE
FVVGYGLDYRELYRNLPYIGTLKPEVYSN
>SAV1064 putative phosphoribosylaminoimidazole carboxylase
MKVAVIMGSSSDWKIMQESCNMLDYFEIPYEKQVVSAHRTPKMMVQFASE
ARERGINIIIAGAGGAAHLPGMVASLTTLPVIGVPIETKSLKGIDSLLSI
VQMPGGIPVATTAIGAAGAKNAGILAARMLSIQNPSLVEKLNQYESSLIQ
KVEDMQNELQ
>SAV2475 hypothetical protein
MNKKHVFVIIGVILCICIVASVIYLKVKYDEKEKQKAIYYKEQQERITLY
LQHNTKEPNTIKSVHFTSLKRGPMGDAVIEGYINENKKDNFTAYATPEHN
YQFGGAMIESERLSELLKPAHQLKSPDEIKEELDKKEGH
>SAV2283 similar to inosine-adenosine-guanosine-nucleoside hydrolase
MTKKVYFNHDGGVDDLVSLFLLLQMENVQLIGVSTIGADCYLEPSLSASV
KIINRFSNEDIQVAPSYERGKNPFPKEWRMHAFFMDALPILNEPVKHVAS
NVSDKEAFEDIIQTLKRQSEKVTLLFTGPLTDLAKALQKDSSIVQYIEKL
VWMGGTFLPKGNVEEPEHDGSAEWNAYWDPEAVKIVFDSDIEIDMVALES
TNQVPLTLDVRQRWANERQYTGIDFLGVSYAAVPPLTHFITNSTYFLWDV
LTTAYIGNKDLVHSIEKKVDVISYGPSQGKTFECKDGRKINVINHVDNNA
FFDYITALAKKVN
>SAV1337 GMP reductase
MKIFDYEDIQLIPNKCIVESRSECDTTIQFGPKKFKLPVVPANMQTVMNE
KLAKWFAENDYFYIMHRFDEEARIPFIKHMQNSGLFASISVGVKKAEFDF
IEKLAQEKLIPEYITIDIAHGHSDSVINMIKHIKNHIPDSFVIAGNVGTP
EGVRELENAGADATKVGIGPGRVCITKIKTGFGTGGWQLAALNICSKAAR
KPLIADGGIRTHGDIAKSIRFGASMVMIGSLFAAHEESPGETVELDGKQY
KEYFGSASEFQKGEHKNVEGKKMFVEHKGSLMDTLKEMQQDLQSSISYAG
GKDLKSLRTVDYVIVRNSIFNGDRD
>SAV0557 similar to deoxypurine kinase
MNKPFIAIEGPIGVGKSSLAHKLSQTLDFYEEKEIITENPFLSDFYEDIS
KWSFQTEMFFLCNRYKQFQDVTQLNQGVVSDYHIHKNKIFAKNTLSPVEF
QKFSKIYDILTEDMIMPNMIIFLDADLDVLKSRIAKRNRSFEHQIEDEYL
LKLKKDYREYYESLQSNGSNVVLIDTTSIDFLKNEQDYEDILHIILPMIG
DITNE
>SAV0243 similar to inosine-uridine preferring nucleoside hydrolase
MKRKIIMDCDPGHDDAIALILAGAIDSPLEILAVTTVAGNQSVDKNTTNA
LNVLDIMGRQDIAVAKGADRPLIKPAAFASEIHGESGLDGPKLPSTPSRQ
AVAMPASDVIINKVMTSDTPVTIVATGPLTNVATALIREPRIAEHIESIT
LMGGGTFGNWTPTAEFNIWVDAEAAKRVFESGITINVFGLDVTHQVLADN
HVIERFESINNPVAQFVVELLQFFKKTYKTHFNMDGGPIHDACTILYLLQ
PELFTMVPVNIDIEHQSPLTYGTMAVDLNHVTGKPANAYFATAVDVEEVW
NLIDHKLRTYE
>SAV1025 similar to nucleotidase
MMEKNENINVEILTTSDMHSHFLNGDYGSNIYRAGTYVNQIRAQNHRVIL
LDSGGSLAGSLAAYYYAIVAPYKRHPMIKLMNRMHYDASGVSPSEFKFGL
SFLTRSIALARFPWLSANIEYNVTKEPYFSTPYCIKHFGDLKIAIVGVTA
DGLMENEYSEMEQDVSIEKTLVASKRWIRYIHEVEEPDFLIVIYHGGLNK
ISNSTKNKKASSNEAEKLMEELGVIDLMITAHQHQTIVGQDHETYYVQAG
QDAKELVHLSINFKKRTTTYDVESIDSKVIDLNEYEEDQELLDLTFYDRK
AVAYWSQEIISDKGLMLSVNGLQDLVCQTHPFSQLLHDAIQLAFDNDITC
VHVPLNGEKGLSGQIRNEDLYHAYPYPDKPMDMTISGQNIKDILEYSYSH
LDFVNEQLSLTIIDETLCTMWQGFNYEIDMNQEPGQRVMLDQIDLTKSYR
VTMTDYCYRNYKNYLKNAIIHESYDETMSTLIAEKLRDPNYRISCSDNFV
VKNR
>SAV0558 similar to cytosine deaminase
MTNDIYFMTLAIEEAKKAAQLGEVPIGAIITKDDEVIARAHNLRETLQQP
TAHAEHIAIERAAKVLGSWRLEGCTLYVTLEPCVMCAGTIVMSRIPRVVY
GADDPKGGCSGSLMNLLQQSNFNHRAIVDKGVLKEACSTLLTTFFKNLRA
NKKSTN
>SAV1067 conserved hypothetical protein
MKTIELHITLQPQVLDTQGQTLTRAVHDLGYAQVNDIRVGKVLYMTVDEV
SDEKVHNIITTLSEKLFANTVIEEYSYKVLDDEKENA
>SAV1974 dUTP pyrophosphatase
MNWLELMRRTRKMTNILQVKLLSENARMPERNHKTDAGYDIFSAETVVLE
PQEKAVIKTDVAVSIPEGYVGLLTSRSGVSSKTHLVIETGKIDAGYHGNL
GINIKNDNETLESEDMSNFGRSPAGIDGKYARLPVTDKILCMNGSYVINK
GDKLAQLVIVPIWTPELKQVEEFESVSERGAKGFGSSGV
>SAV2132 hypothetical protein
MTNNGNEPNLTLSDLYDKDVVYTSRPSYISNPWLKPDEHQSNFLTGRELL
IANQLPVIVHEASATDKLHQLFQVIGKEVPNSIFTFNNQQSYENLIKQLA
HKENKKIYFQYIHDETILNQQYYALDKTLFVALNNKARIPEWTNGKFLPK
RKVVKIEQFENEIKNWEFPLVIKPGDDLPTAGGYGVMICYHDADLQKAIT
RIKEATAETNSLIIEQKIEEKANYCVQFAYSESLGIQYLGAATQLTDKYG
FYNGNENTTNVPEHVIEAGRQIMENGVNQGFFGVAGFDLLVDEDDNVYAI
DLNFRQNGSTSMLLLANELNSGYQKFYSYHSKGDNTHFFNTILKYVKEGS
LYPLSYYDGDWYGEDKVKSRFGCIWHGDSKETVLENERAFLAELEHY
>SAV0923 conserved hypothetical protein
MRLTIYHTNDIHSHLHEYERIKVYMAEQRPRLNHPSLYVDLGDHVDLSAP
ITEATLGKKNVALLNEAKCDVATIGNNEGMTISHEALNHLYDEAKFIVTC
SNVIDESGHLPNNIVSSYIKDMDGVKILFVAATAPFTPFYRALDWIVTDP
LESIKEEIKHQRGKFDVIIVLSHCGIFFDETLCQELPEIDVIFGSHTHHY
FEHGEINNGVLMAAAGKYGNYLGEVNLTFEAHKVVHKTAKIIPLETLPEV
ETSFEEEGKTLMSNSVIQHPVVLKRSMNHITEAAYLLAQSVCEYTHAQCA
IINAGLLVKDIVKDEVTEYDIHQMLPHPINMVRVRLSGVKLKEIITKSNK
QEYMYEHAQGLGFRGNIFGGYILYNLGYIHSTGRYYLNGEEIEDDKEYVL
GTIDMYTFGRYFPTLKELPKEYLMPEFLRDIFKEKLLEY
>SAV2229 adk, adenylate kinase
MNIILMGLPGAGKGTQASEIVKKFPIPHISTGDMFRKAIKEETELGKEAK
SYMDRGELVPDEVTVGIVKERISEDDAKKGFLLDGFPRTIEQAEALNNIM
SELDRNIDAVINIEVPEEELMNRLTGRRICESCGTTYHLVFNPPKVEGIC
DIDGGKLYQREDDNPETVANRLSVNIKQSKPILDFYDQKGVLKNIDGSKD
ISDVTKDVIDILDHL
>SAV1635 apt, adenine phosphoribosyl transferase
MDLKQYVSEVQDWPKPGVSFKDITTIMDNGEAYGYATDKIVEYAKDRDVD
IVVGPEARGFIIGCPVAYSMGIGFAPVRKEGKLPREVIRYEYDLEYGTNV
LTMHKDAIKPGQRVLITDDLLATGGTIEAAIKLVEKLGGIVVGIAFIIEL
KYLNGIEKIKDYDVMSLISYDE
>SAV1568 cdd, cytidine deaminase
MSYQPHYFQEVRKAQQESYSPYSQFKVGAYLKTKDGRTFYGTNVENASYP
LSICAERASLVSAISQGYRPGDFESITVTVDADKPSSPCGACRQVLKELC
DDDMPVYMTNHKGDMVMMTVAELLPFGFSGKDLE
>SAV1478 cmk, cytidylate kinase
MKAINIALDGPAAAGKSTIAKRVASELSMIYVDTGAMYRALTYKYLKLNK
TEDFAKLVDQTTLDLTYKADKGQCVILDNEDVTDFLRNNDVTQHVSYVAS
KEPVRSFAVKKQKELAAEKGIVMDGRDIGTVVLPDADLKVYMIASVEERA
ERRYKDNQLRGIESNFEDLKRDIEARDQYDMNREISPLRKADDAVTLDTT
GKSIEEVTDEILAMVSQIK
>SAV1589 comEB, late competence operon required for DNA binding and uptake
MERIKWEEYFMAQSHLLALRSTCQRLSVGATIVKDNRIIAGGYNGSVAGE
VHCIDEGCLIEDGHCIRTIHAEMNALLQCAKQGVSTEGATIYVTHFPCLN
CTKSIIQAGIKRIYYAEDYHNHEYATKLLKQSGIEFKKIPFSPEYVAKYL
TKG
>SAV2138 deoD, purine nucleoside phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFG
YTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQEN
VNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGAT
THVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKAL
GIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>SAV0138 dra, deoxyribose-phosphate aldolase
MKFEKYIDHTLLKPESTRTQIDQIIDEAKAYNFKSVCVNPTHVKYAAERL
ADSEVLVCTVIGFPLGASTTATKAFETEDAIQNGADEIDMVINIGALKDG
RFDDVQQDIEAVVKAAKGHTVKVIIETVLLDHDEIVKASELTKAAGADFV
KTSTGFAGGGATAEDVKLMKDTVGADVEVKASGGVRNLEDFNKMVEAGAT
RIGASAGVQIMQGLEADSDY
>SAV1732 fhs, formyltetrahydrofolate synthetase
MTHLSDLDIANQSTLQPIKDIAASVGISEDALEPYGHYKAKIDINKITPR
ENKGKVVLVTAMSPTPAGEGKSTVTVGLADAFHELNKNVMVALREPALGP
TFGIKGGATGGGYAQVLPMEDINLHFNGDFHAITTANNALSAFIDNHIHQ
GNELGIDQRRIEWKRVLDMNDRALRHVNVGLGGPTNGVPREDGFNITVAS
EIMAILCLSRSIKDLKDKISRITIGYTRDRKPVTVADLKVQGALAMILKD
AIKPNLVQSIEGTPALVHGGPFANIAHGCNSILATETARDLADIVVTEAG
FGSDLGAEKFMDIKAREAGFDLAAVVVVATIRALKMHGGVAKDNLKEENV
EAVKAGIVNLERHVNNIKKFGVEPVVAINAFIHDTDAEVEYVKSWAKENN
VRIALTEVWEKGGKGGVDLANEVLEVIDQPNSFKPLYELELPLEQKIEKI
VTEIYGGSKVTFSSKAQKQLKQFKENGWDNYPVCMAKTQYSFSDDQTLLG
APSGFEITIRELEAKTGAGFIVALTGAIMTMPGLPKKPAALNMDVTDDGH
AIGLF
>SAV1209 gmk, guanylate kinase homolog
MDNEKGLLIVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEV
DGVDYFFKTRDAFEALIKDDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDV
FLEIEVEGAKQVRKKFPDALFIFLAPPSLDHLRERLVGRGTESNEKIQSR
INEARKEVEMMNLYDYVVVNDEVELAKNRIQCIVEAEHLKRERVEAKYRK
MILEAKK
>SAV0391 guaA, GMP synthase
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMN
PKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKV
ERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIAD
SPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCKGQWT
MENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIF
VDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRK
IIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVG
GLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRV
LGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGD
YRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVY
DITSKPPSTIEWE
>SAV1838 hit, Hit-like protein involved in cell-cycle regulation
MSETIFGKILTGEIPSFKVYEDDYVYAFLDISQVTKGHTLLIPKKASANI
FETDEETMKHIGAALPKVANAIKRAFNPDGLNIIQNNGEFADQSVFHIHF
HLIPRYENDIDGFGYKWETHEDILDNDAKQQIAEQIQAQF
>SAV1469 ndk, nucleoside diphosphate kinase
MERTFLMIKPDAVQRNLIGEVISRIERKGLKLVGGKLMQVPMELAETHYG
EHQGKPFYNDLISFITSAPVFAMVVEGEDAVNVSRHIIGSTNPSEASPGS
IRGDLGLTVGRNIIHGSDSLESAEREINLWFNENEITSYASPRDAWLYE
>SAV2617 nrdD, anaerobic ribonucleoside-triphosphate reductase
MNQIEEALTGLISKDPAIVNENANKDSDTFSTMRDLTAGIVSKSYALNYL
LPKHVADAHQRGDIHFHDLDYHPFQPLTNCCLIDAKNMLHNGFEIGNANV
TSPKSIQTASAQLVQIIANVSSSQYGGCTVDRVDELLSTYARHNEEQHRN
IAKQFVKESEIDRYVDQQVTKDINDAIESLEYEINTLYTSNGQTPFVTLG
FGLGTDHLSRKIQQAILNTRIKGLGKDRTTAIFPKLVFSIKKGTNFSPQD
PNYDIKQLALKCSTKRMYPDILNYDKLVEILGDFKAPMGCRSFLPSWKDA
EGHFENNGRCNLGVVTLNLPRMALESAGNMTKFWEIFYERIDVLHDALLY
RINRLKDAVPNNAPILYKSGAFNYKLKETDDVAELFKNKRATISMGYIGL
YETATVFYGPDWETSQEAKAFTLEILKEMKRYQTKWTELYDIWFSIYSTP
SESLTDRFCRLDQERFGDIKDITDKGYYQNSFHYDVRKDVTPFEKLDFEK
DYPYYASGGFIHYCEYPKLQHNLKALEAVWDYSYDKVGYLGTNIPIDHCY
ECDYDGDFEATEKGFKCPNCGNDNPKTVDVVKRTCGYLGNPVQRPVIKGR
HKEICARVKHMKAPKE
>SAV0731 nrdE, ribonuceloside diphosphate reductase major subunit
MEKTKTLLNLRTRWVILMKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQ
EALVAYLEEVKDKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITD
YAKSISFNFASYMSASKFFKDYALKTNDKSQYLEDYNQHVAIVALYLANG
NKAQAKQFISAMVEQRYQPATPTFLNAGRARRGELVSCFLLEVDDSLNSI
NFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPIAKSLEG
GFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGL
IVPSKFFDLAKEGKDFYMFAPHTVKEEYGVTLDDIDLEKYYDDMVANPNV
EKKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLC
TEIFQLQETSIINDYGIEDEIKRDISCNLGSLNIVNVMESGKFRDSVHSG
MDALTVVSDVANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGYESE
EAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDYANGKYFEFYT
TQEFEPQFEKVRELFDGMAIPTSEDWKKLQQDVEQYGLYHAYRLAIAPTQ
SISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTMWYYKSAFNT
DQMKLIDLIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKSL
YYTRNKLLSVEECTSCSI
>SAV0732 nrdF, ribonucleoside-diphosphate reductase minor subunit
MIAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLSEAEQDTF
KKALAGLTGLDTHQADDGMPLVMLHTTDLRKKAVYSFMAMMEQIHAKSYS
HIFTTLLPSSETNYLLDEWVLEEPHLKYKSDKIVANYHKLWGKEASIYDQ
YMARVTSVFLETFLFFSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGV
FTGLDAQHLRNELSESEKQKADQEMYKLLNDLYLNEESYTKMLYDDLGIT
EDVLNYVKYNGNKALSNLGFEPYFEEREFNPIIENALDTTTKNHDFFSVK
GDGYVLALNVEALQDDDFVFDNK
>SAV0730 nrdI, NrdI protein involved in ribonucleotide reductase function
MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFG
EVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMK
FELHGKNKDVIEFKNKVGNFNENHGREKVQSY
>SAV0521 nupC, pyrimidine nucleoside transport protein
MHILIGIIGIIFFLALAFLFSSDRKNIRWKYVGILLAIQLIFAFILLKTT
MGIKVIGGISNGFNYLLLKAADGVNFVFGGIQYIDPKQPPFFFSVLLPIV
FISAIIGILQYTKILPLIINVLGFLISKINGMGRLESYNAVAAAILGQSE
VFISIKKQLPYIPKQRLYTLTASAMSTVSASIIGAYFTLIEPKYVVTAVV
LNLFGGFIIASIINPYKVNEEDDKLLVEETEERQQSFFEMLGEYILDGFK
VAVIVGAMLIGYIAIIALLNGIVSNIFSTVSGGAISWDFQTLIGFVFAPF
AFLVGVPWQDAVQAGSVMATKLLSNEFVAMQALGKLSDLSEHAKGVTSVF
LVSFANFSSIGIISGAIKSLNDKKGDTVARFGLKLLFGATLVSFISAAIA
GFFI
>SAV0389 pbuX, xanthine permease
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVA
TFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILV
IIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDV
KNILLGLMTLIIILVLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQ
VNHAGWLGIPVPFRFSGFSFDVTSTLVFFILAIVSLIESTGVYHALSEIT
GKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNN
VIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILG
HIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAI
SAIILNFFFNGIKYKQTEENVK
>SAV2136 pdp, pyrimidine nucleoside phosphorylase
MLCPKLFKKRMIKMRMIDIIEKKRDGHTLTTEEINFFIDGYVKGDIPDYQ
ASSLAMAIYFQDMNDDERAALTMAMVNSGDMIDLSDIKGVKVDKHSTGGV
GDTTTLVLAPLVAAVDVPVAKMSGRGLGHTGGTIDKLEAIDGFHVEIDEA
TFVKLVNENKVAVVGQSGNLTPADKKLYALRDVTGTVNSIPLIASSIMSK
KIAAGADAIVLDVKTGSGAFMKTLEDAEALAHAMVRIGNNVGRNTMAIIS
DMNQPLGRAIGNALELQEAIDTLKGQGPKDLTELVLTLGSQMVVLANKAE
TLEEARALLIEAINSGAALEKFKTFIKNQGGDETVIDHPERLPQAQYQIE
YKAKKSGYVTELVSNDIGVASMMLGAGRLTKEDDIDLAVGIVLNKKIGDK
VEEGESLLTIHSNRQDVDDVVKKLDSSITIADHVVSPTLIHKIITE
>SAV1599 pfs, 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase
MIGIIGAMEEEVTILKNKLTQLSEISVAHVKFYTGILKDREVVITQSGIG
KVNAAISTTLLINKFKPDVIINTGSAGALDESLNVGDVLISDDVKYHDAD
ATAFGYEYGQIPQMPVAFQSSKPLIEKVSQVVQQQQLTAKVGLIVSGDSF
IGSVEQRQKIKKAFPNAMAVEMEATAIAQTCYQFNVPFVVVRAVSDLANG
EAEMSFEAFLEKAAVSSSQTVEALVSQL
>SAV0136 pnp, purine nucleoside phosphorylase
MKSTPHIKPMNDVEIAETVLLPGDPLRAKFIAETYLDDVEQFNTVRNMFG
FTGTYKGKKVSVMGSGMGMPSIGIYSYELIHTFGCKKLIRVGSCGAMQEN
IDLYDVIIAQGASTDSNYVQQYQLPGHFAPIASYQLLEKAVETARDKGVR
HHVGNVLSSDIFYNADTTASERWMRMGILGVEMESAALYMNAIYAGVEAL
GVFTVSDHLIHETSTTPEERERAFTDMIEIALSLV
>SAV0500 prs, ribose-phosphate pyrophosphokinase
MLNNEYKNSSLKIFSLKGNEALAQEVADQVGIELGKCSVKRFSDGEIQIN
IEESIRGCDVFIIQPTSYPVNLHLMELLIMIDACKRASAATINIVVPYYG
YARQDRKARSREPITAKLVANLIETAGATRMIALDLHAPQIQGFFDIPID
HLMGVPILAKHFKDDPNINPEECVVVSPDHGGVTRARKLADILKTPIAII
DKRRPRPNVAEVMNIVGEIEGRTAIIIDDIIDTAGTITLAAQALKDKGAK
EVYACCTHPVLSGPAKERIENSAIKELIVTNSIHLDEDRKPSNTKELSVA
GLIAQAIIRVYERESVSVLFD
>SAV0017 purA, adenylosuccinate synthase
MSSIVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETY
KLHLVPSGIFYKDKLAVIGNGVVVDPVALLKELDGLNERGIPTSNLRISN
RAQVILPYHLAQDEYEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADL
LEKETFERLLKSNIEYKQAYFKGMFNETCPSFDDIFEEYYAAGQRLKEFV
TDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVTSSNPIAGNVTVG
TGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTT
GRPRRVGWFDSVVLRHSRRVSGITDLSINSIDVLTGLDTVKICTAYELDG
KEITEYPANLDQLKRCKPIFEELPGWTEDVTSVRTLEELPENARKYLERI
SELCNVQISIFSVGPDREQTNLLKELW
>SAV1908 purB, adenylosuccinate lyase
MIERYSREEMSNIWTDQNRYEAWLEVEILACEAWSELGHIPKADVQKIRQ
NAKVNVERAQEIEQETRHDVVAFTRQVSETLGEERKWVHYGLTSTDVVDT
ALSFVIKQANDIIEKDLERFIDVLAEKAKNYKYTLMMGRTHGVHAEPTTF
GVKMALWYTEMQRNLQRFKQVREEIEVGKMSGAVGTFANIPPEIESYVCK
HLGIGTAPVSTQTLQRDRHAYYIATLALIATSLEKFAVEIRNLQKTETRE
VEEAFAKGQKGSSAMPHKRNPIGSENITGISRVIRGYITTAYENVPLWHE
RDISHSSAERIMLPDVTIALDYALNRFTNIVDRLTVFEDNMRNNIDKTFG
LIFSQRVLLALINKGMVREEAYDKVQPKAMISWETKTPFRELIEQDESIT
SVLTKEELDECFDPKHHLNQVDTIFERAGLA
>SAV1066 purC, phosphoribosylaminoimidazolesuccinocarboxamide synthetase homolog
MTLLYEGKAKRIFSTNQENELRVEYKDEVTAGNGAKKDTMAGKGRLNNQI
TSIIFKYLQENGIESHFIKQLSETEQLVKPVKIIPLEVVVRNIASGSITK
RLGFENGEVFREPLVEFFYKNDALNDPLITDDHVKLLNIASDEDIEILKS
KALKINNVLKQLMDAMNLKLVDFKIEFGKTETGQILLADEISPDTCRIWD
KATNANFDKDVYRNNTGSLIETYQIFLNKLEDLK
>SAV1074 purD, phosphoribosylamine-glycine ligase
MTPIAEVHTEISESNHQGILDFAKQQNVDWVVIGPEQPLIDGLADILRAN
GFKVFGPNKQAAQIEGSKLFAKKIMKKYNIPTADYKEVERKKDALTYIEN
CELPVVVKKDGLAAGKGVIIADTIEAARSAIEIMYGDEEEGTVVFETFLE
GEEFSLMTFVNGDLAVPFDCIAQDHKRAFDHDEGPNTGGMGAYCPVPHIS
DDVLKLTNETIAQPIAKAMLNEGYQFFGVLYIGAILTKDGPKVIEFNARF
GDPEAQVLLSRMESDLMQHIIDLDEGKRTEFKWKNESIVGVMLASKGYPD
AYEKGHKVSGFDLNENYFVSGLKKQGDTFVTSGGRVILAIGKGDNVQDAQ
RDAYEKVSQIQSDHLFYRHDIANKALQLK
>SAV1070 purF, phosphoribosylpyrophosphate amidotransferase
MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSDQNE
LKGERGLGLLTEAINDDQMERLKGYQHAIGHVRYATSGNKGIENIQPFLY
HFYDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKA
PTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTY
ILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAISAME
YIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAAS
GYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGK
NIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFPSFYGIDVS
TTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVE
SFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV
>SAV1073 purH, bifunctional purine biosynthesis protein
MMKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVS
DLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVV
NLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADY
HEVLTRLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGE
NPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATLALVKKFDTP
AAVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELA
EQLHSIFLEVIIAPKFTDEALDILKQKKNVRLLEIDMTIDSNEEEFVSVS
GGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAII
LSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVE
LAAQHGIKAIIQPGGSIKDQDSIDMANKHGIAMVVTGTRHFKH
>SAV1065 purK, phosphoribosylaminoimidazole carboxylase carbon dioxide-fixation chain PurK homolog
MNFNKLKFGATIGIIGGGQLGKMMAQSAQKMGYKVVVLDPSEDCPCRYVA
HEFIQAKYDDEKALNQLGQKCDVITYEFENISAQQLKLLCEKYNIPQGYQ
AIQLLQDRLTEKETLKSAGTKVVPFISVKESTDIDKAIETLGYPFIVKTR
FGGYDGKGQVLINNEKDLQEGFKLIETSECVAEKYLNIKKEVSLTVTRGN
NNQITFFPLQENEHRNQILFKTIVPARIDKTAEAKEQVNKIIQSIHFIGT
FTVEFFIDSNNQLYVNEIAPRPHNSGHYSIEACDYSQFDTHILAVTGQSL
PNSIELLKPAVMMNLLGKDLDLLENEFNEHPEWHLHIYGKSGRKDSRKMG
HMTVLTNDVNQTEQDMYAKFEGSN
>SAV1069 purL, phosphoribosylformylglycinamidine synthetase
MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVM
WSEHCSYKHSKPFLKQFPTSGEHVLMGPGEGAGVVDIGDNQAVVFKVESH
NHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRL
LKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQ
KGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPF
VGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQ
VPTREPGISPYEMMLSETQERMLLVVEKGNEQKFLDLFDKHELDSAVIGE
VTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHI
DVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTN
KAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYG
SPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPV
VGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHE
FESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLG
LKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVT
TPYTEISENVSDIKQIWEGAIAQCLTTQD
>SAV1071 purM, phosphoribosylformylglycinamidine cyclo-ligase
MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGATFDLSQL
NMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPL
YFLDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGE
YDVAGFAVGAVEKDDYVDGSEVKEGQVVIGLASSGIHSNGYSLVRKLINE
SGIDLASNFDNRPFIDVFLEPTKLYVKPVLALKKEVSIKAMNHITGGGFY
ENIPRALPAGYAARIDTTSFPTPKIFDWLQQQGNIDTNEMYNIFNMGIGY
TVIVDEKDASRALKILAEQNVEAYQIGHIVKNESTAIELLGV
>SAV1072 purN, phosphoribosylglycinamide formyltransferase
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKK
HDIPVYINEPKQFDSKAAYEQHLVTLLNKDKVEWIILAGYMRLIGPDLLA
SFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDCGMDTGEI
IEQRQCDIRPDDSKEQLEEKVKKLEYELYPSVIAKIVK
>SAV1068 purQ, phosphoribosylformylglycinamidine synthase I
MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGVLIPGGF
SFGDYLRSGAMASVAPIISEVKRLATEGKPVLGVCNGFQILTEIGLLPGA
LLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTD
EIYQQLKANNQIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERALET
LLGTDSGVKLFEAMVKSWREQHV
>SAV0496 purR, pur operon repressor homologue
MRYKRSERIVFMTQYLMNHPNKLIPLTFFVKKFKQAKSSISEDVQIIKNT
FQKEKLGTVITTAGASGGVTYKPMMSKEEATEVVNEVITLLEEKERLLPG
GYLFLSDLVGNPSLLNKVGKLIASIYMEEKLDAVVTIATKGISLANAVAN
ILNLPVVVIRKDNKVTEGSTVSINYVSGSSRKIETMVLSKRTLAENSNVL
VVDDFMRAGGSINGVMNLMNEFKAHVKGVSVLVESKEVKQRLIEDYTSLV
KLSDVDEYNQEFNVEPGNSLSKFS
>SAV1202 pyrAA, carbamoyl-phosphate synthase small chain
MQSKRYLVLEDGSFYEGYRLGSDNLTVGEIVFNTAMTGYQETISDPSYTG
QIITFTYPLIGNYGINRDDFESLVPTLNGIVVKEASAHPSNFRQQKTLHD
VLELHQIPGIAGVDTRSITRKIRQHGVLKAGFTDRKEDIDQLVKHLQQVE
LPKNEVEIVSTKTPYVSTGKDLSVVLVDFGKKQNIVRELNVRGCNVTVVP
YTTTAEEILAMAPDGVMLSNGPGNPEVVECAIPMIQGILGKIPFFGICLG
HQLFALSQGASSFKMKFGHRGANHPVKNLETGKVDITSQNHGYAIDIDSL
KSTDLEVTHLALNDGTVEGLKHKTLPAFSVQYHPEANPGPSDSNYLFDDF
VAMMTNFKEKERHINA
>SAV1203 pyrAB, carbamoyl-phosphate synthase large chain
MPKRNDIKTILVIGSGPIIIGQAAEFDYAGTQACLALKEEGYRVILVNSN
PATIMTDKEIADKVYIEPLTHDFIARIIRKEQPDALLPTLGGQTGLNMAI
QLHESGVLQDNNVQLLGTELTSIQQAEDREMFRTLMNDLNVPVPESDIVN
TVEQAFKFKEQVGYPLIVRPAFTMGGTGGGICHNDEELHEIVSNGLHYSP
ATQCLLEKSIAGFKEIEYEVMRDKNDNAIVVCNMENIDPVGIHTGDSIVV
APSQTLSDVEYQMLRDVSLKVIRALGIEGGCNVQLALDPHSFDYYIIEVN
PRVSRSSALASKATGYPIAKLAAKIAVGLTLDEMLNPITGTSYAAFEPTL
DYVISKIPRFPFDKFEKGERELGTQMKATGEVMAIGRTYEESLLKAIRSL
EYGVHHLGLPNGESFDLDYIKERISHQDDERLFFIGEAIRRGTTLEEIHN
MTQIDYFFLHKFQNIIDIEHQLKEHQGDLEYLKYAKDYGFSDKTIAHRFN
MTEEEVYQLRMENDIKPVYKMVDTCAAEFESSTPYYYGTYETENESIVTD
KEKILVLGSGPIRIGQGVEFDYATVHAVWAIQKAGYEAIIVNNNPETVST
DFSISDKLYFEPLTEEDVMNIINLEKPKGVVVQFGGQTAINLADKLAKHG
VKILGTSLENLNRAEDRKEFEALLRKINVPQPQGKSATSPEEALANAAEI
GYPVVVRPSYVLGGRAMEIVDNDKELENYMTQAVKASPEHPVLVDRYLTG
KEIEVDAICDGETVIIPGIMEHIERAGVHSGDSIAVYPPQTLTEDELATL
EDYTIKLAKGLNIIGLINIQFVIAHDGVYVLEVNPRSSRTVPFLSKITDI
PMAQLAMRAIIGEKLTDMGYQEGVQPYAEGVFVKAPVFSFNKLKNVDITL
GPEMKSTGEVMGKDTTLEKALFKGLTGSGVEVKDHGTVLMTVSDKDKEEV
VKLAQRLNEVGYKILATSGTANKLAEYDIPAEVVGKIGGENDLLTRIQNG
DVQIVINTMTKGKEVERDGFQIRRTTVENGIPCLTSLDTANALTNVIESM
TFTMRQM
>SAV1200 pyrB, aspartate transcarbamoylase chain A
MNHLLSMEHLSTDQIYKLIQKASQFKSGERQLPNFEGKYVANLFFENSTR
TKCSFEMAELKLGLKTISFETSTSSVSKGESLYDTCKTLESIGCDLLVIR
HPFNNYYEKLANINIPIANAGDGSGQHPTQSLLDLMTIYEEYGYFEGLNV
LICGDIKNSRVARSNYHSLKALGANVMFNSPNAWIDDSLEAPYVNIDDVI
ETVDIVMLLRIQHERHGLAEETRFAADDYHQKHGLNEVRYNKLQEHAIVM
HPAPVNRGVEIQSDLVEASKSRIFKQMENGVYLRMAVIDELLK
>SAV1201 pyrC, dihydroorotase
MKLIKNGKVLQNGELQQADILIDGKVIKQIAPAIEPSNGVDIIDAKGHFV
SPGFVDVHVHLREPGGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSV
EHFEALQKLIDDNAQVRVLPYASITTRQLGKELVDFPALVKEGAFAFTDD
GVGVQTASMMYEGMIEAAKVNKAIVAHCEDNSLIYGGAMHEGKRSKELGI
PGIPNICESVQIARDVLLAEAAGCHYHVCHVSTKESVRVIRDAKRAGIHV
TAEVTPHHLLLTEDDIPGNNAIYKMNPPLRSTEDREALLEGLLDGTIDCI
ATDHAPHARDEKAQPMEKAPFGIVGSETAFPLLYTHFVKNGDWTLQQLVD
YLTIKPCETFNLEYGTLKENGYADLTIIDLDSEQEIKGEDFLSKADNTPF
IGYKVYGNPILTMVEGEVKFEGDK
>SAV1205 pyrE, orotate phosphoribosyltransferase
MAKEIAKSLLDIEAVTLSPNDLYTWSSGIKSPIYCDNRVTLGYPLVRGAI
RDGLINLIKEHFPEVEVISGTATAGIPHAAFIAEKLKLPMNYVRSSNKSH
GKQNQIEGAKSEGKKVVVIEDLISTGGSSVTAVEALKQAGAEVLGVVAIF
TYGLKKADDTFSNIQLPFYTLSDYNELIEVAENEGKISSEDIQTLVEWRD
NLA
>SAV1204 pyrF, orotidine-5-phosphate decarboxylase
MKDLPIIALDFESKEKVNQFLDLFDESLFVKVGMELFYQEGPQLINEIKE
RGHDVFLDLKLHDIPNTVGKAMEGLAKLNVDLVNVHAAGGVKMMSEAIKG
LRKHNQHTKIIAVTQLTSTTEDMLRHEQNIQTSIEEAVLNYAKLANAAGL
DGVVCSPLESRMLTEKLGTSFLKVTPGIRPKGASQDDQHRITTPEEARQL
GSTHIVVGRPITQSDNPVESYHKIKESWLV
>SAV2127 pyrG, CTP synthase
MTKFIFVTGGVVSSLGKGITASSLGRLLKDRGLNVTIQKFDPYLNVDPGT
MSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKFSNVTAGKVYSHVLK
KERRGDYLGGTVQVIPHITNEIKERLLLAGESTNADVVITEIGGTTGDIE
SLPFIEAIRQIRSDLGRENVMYVHCTLLPYIKAAGEMKTKPTQHSVKELR
GLGIQPDLIVVRTEYEMTQDLKDKIALFCDINKESVIECRDADSLYEIPL
QLSQQNMDDIVIKRLQLNAKYETQLDEWKQLLDIVNNLDGKITIGLVGKY
VSLQDAYLSVVESLKHAGYPFAKDIDIRWIDSSEVTDENAAEYLADVDGI
LVPGGFGFRASEGKISAIKYARENNVPFFGICLGMQLATVEFSRNVLGLE
GAHSAELDPATPYPIIDLLPEQKDIEDLGGTLRLGLYPCSIKEGTLAQDV
YGKAEIEERHRHRYEFNNDYREQLEANGMVISGTSPDGRLVEMVEIPTND
FFIACQFHPEFLSRPNRPHPIFKSFIEASLKYQQNK
>SAV1199 pyrP, uracil permease
MQNDEMFERTVKPVLDVNEKPQPAQWAFLSLQHLFAMFGATVLVPFLTGL
PISAALLASGIGTLLYILITKAQIPAYLGSSFAFITPIITGLSTHSLGDM
LVALFMSGVMYVIIGILIKLSGTAWLMKLLPPVVVGPVIMVIGLSLAPTA
VNMAMYENPGDMKGYNISFLIVAMITLLVTIVVQGFFKGFLSLIPVLVGI
IVGYVVAIFMGIVKFDAIMSAKWIDFPHIYLPFKDYVPSFHLGLVLVMIP
IVFVTVSEHIGHQMVLNKIVGRNFFEKPGLDKSIIGDGVSTMFASIIGGP
PSTTYGENIGVLAITRIYSIYVIGGAAVIAIVLAFIGKFTALISSIPTPV
MGGVSILLFGIIAASGLRMLVESKVDFANNRNLVIASVILVVGIGNLVFN
LKEIGINLQIEGMALAALSGIILNLILPKEKKQNN
>SAV1198 pyrR, pyrimidine operon repressor chainA
MSERIIMDDAAIQRTVTRIAHEILEYNKGTDNLILLGIKTRGEYLANRIQ
DKIHQIEQQRIPTGTIDITYFRDDIEHMSSLTTKDAIDIDTDITDKVVII
IDDVLYTGRTVRASLDAILLNARPIKIGLAALVDRGHRELPIRADFVGKN
IPTSKEETVSVYLEEMDQRNAVIIK
>SAV1258 smbA, uridylate kinase
MAQISKYKRVVLKLSGEALAGEKGFGINPVIIKSVAEQVAEVAKMDCEIA
VIVGGGNIWRGKTGSDLGMDRGTADYMGMLATVMNALALQDSLEQLDCDT
RVLTSIEMKQVAEPYIRRRAIRHLEKKRVVIFAAGIGNPYFSTDTTAALR
AAEVEADVILMGKNNVDGVYSADPKVNKDAVKYEHLTHIQMLQEGLQVMD
STASSFCMDNNIPLTVFSIMEEGNIKRAVMGEKIGTLITK
>SAV2119 tdk, thymidine kinase
MYETYHSGWIECITGSMFSGKSEELIRRLRRGIYAKQKVVVFKPAIDDRY
HKEKVVSHNGNAIEAINISKASEIMTHNLTNVDVIGIDEVQFFDDEIVSI
VEKLSADGHRVIVAGLDMDFRGEPFEPMPKLMAVSEQVTKLQAVCAVCGS
SSSRTQRLINGKPAKIDDPIILVGANESYEPRCRAHHIVAPSDNNKEEL
>SAV1427 thyA, thymidylate synthase
MLNSFDAAYHSLCEEVLEIGNTRNDRTNTGTISKFGHQLRFDLSKGFPLL
TTKKVSFKLVATELLWFIKGDTNIQYLLKYNNNIWNEWAFENYIKSDEYN
GPDMTDFGHRALSDPEFNEQYKEQMKQFKQRILEDDTFAKQFGDLGNVYG
KQWRDWVDKDGNHFDQLKTVIEQIKHNPDSRRHIVSAWNPTEIDTMALPP
CHTMFQFYVQDGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAKECGLE
VGEFVHTFGDAHIYSNHIDAIQTQLARESFNPPTLKINSDKSIFDINYED
LEIVDYESHPAIKAPIAV
>SAV0482 tmk, thymidylate kinase homologue
MSAFITFEGPEGSGKTTVINEVYHRLVKDYDVIMTREPGGVPTGEEIRKI
VLEGNDMDIRTEAMLFAASRREHLVLKVIPALKEGKVVLCDRYIDSSLAY
QGYARGIGVEEVRALNEFAINGLYPDLTIYLNVSAEVGRERIIKNSRDQN
RLDQEDLKFHEKVIEGYQEIIHNESQRFKSVNADQPLENVVEDTYQTIIK
YLEKI
>SAV1611 udk, uridine kinase
MKATTIIGIAGGSGSGKTTVTNEIMKNLEGHSVALLAQDYYYKDQKHLTF
DERLETNYDHPFAFDNDLLIENLKDLKNGKAVEVPTYDYASHTRSDITID
FKPKDVIIVEGIFALENKVLRDMMDVKIYVDTDADLRILRRLTRDTKERG
RSMDSVINQYLSVVRPMHDQFIEPTKKYADIIIPEGGSNKVAIDIMTTKI
QSLVSKQ
>SAV2112 upp, uracil phosphoribosyl transferase
MSKVHVFDHPLIQHKLSYIRDVNTGTKEFRELVDEVGMLMAYEVTRDLEL
QDVDIETPVTKMTAKRLAGKKLAIVPILRAGLGMTDGILSLVPAARVGHI
GLYRDPETLKAVEYFAKLPQDITERQIIVVDPMLATGASAIEAITSLKKR
GAKNIRFMCLIAAPEGVEKMHEAHPDVDIYIAALDEKLNDKAYITPGLGD
AGDRLFGTK
>SAV0388 xprT, xanthine phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKG
ITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFT
KNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGI
GIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE