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# Francisella tularensis subsp. tularensis SCHU S4, SCHU S4

>FTT0610 DNA/RNA endonuclease family protein
MTKKTSKQKDTKKQTTKKPINYIKIFILLALTIGGGFSGIFFDKFDLKEK
FINFRHAVYNYFTSEPIKHYTTKDNENIIARFFSQSDEGKKQQQQSNEFD
NLKQYPPVRTLPAVTDYCHGFLAYGNPSYGVTDGLGQANLYLCRDGYVVG
YNYQTKEASWVAFKLTKSKVANHLKRDDRFKEDSDVPFVYRAILDDYSRS
GYDRGHLASYASMDFSKKSADQSFLLSNMSPQKAGLNRQGWERLETYERI
WANMYDSIYVYTGPIYKKQKIHKTIGDNKIAVPDYFFKIIYVPSKNQAIA
FVMPNARVEKTKIANYRVSIKDIEQCTGLHFLTNISNRDAVINSVSLMWR
TAYL
>FTT0823 MutT protein
MWYILFYLLGKDKLMHKDKIFEFIKKVQAISHTGIVYSKCPYALDNYHEL
LELSSKMLHEYIKSDVQPYDIYRDMYYPTPQPGVRVVIFKDDKLMMTEDA
DTPNEWTIPGGWCDIDLSPVETCIKEVKEETGYDIKVVKFLALMDRNKYT
QSEIYNVYSLVFLAQIIGGENNPNFEVKKVDFFEIDKLPKLSHKLTKTEL
NIILEAYKQDIIYFE
>FTT1560 HAM1 protein
MKEIVLASSNKGKIREFTNIFKQKNIKILPQTDFNVSDADEIGLSFIENA
ILKARNCAKHTGLPAIADDSGLEVFSLNGEPGIYSARYSGEHGNDKANIQ
KLLAKLTGNDNRNARFVCALAYVKHEFDPAPILAYGFLEGKIAHKISGSN
GFGYDPIFILPQLQKTLAEISETDKNKISHRAIALDKIMQLL
>FTT1477c conservered hypothetical protein
MFKLDSRLAADTFEVCEHLDCKILVMNNSIVPWFIVVPFTDRTEWYQLDD
SQQYNINKIINKLSDFIVKEYNADKLNVATIGNVVRQMHIHVVGRFESDP
VWPAPVWGNIEPKAYTDQEKNKLREKVRSIF
>FTT0909 glutamine amidotransferase, class I
MKIAILQTDHIPEHRRGVAGGNYPEMFANLFFKLSVVVDFDIFDVTMQEY
PQDYDIYDGFIITGSKATAFDNLAWIIKLKTEIVKLHDNHKKIIGICFGH
QILAQALGGRVERGPKGFAVGVRNVEILTRKPWMEPFHSYLSLLFYHQDM
VVKLPQGAELISTSDYCKVQMFCINNHILGIQAHPEMLKVHKHALIKEYQ
DDIKNEFHHALESLRIRDNSLIIAHWMANFFEYKD
>FTT0184 Zinc-binding domain protein
MSNYSDQDIFFMQKAYQQALLAYQAGEVPIGAVLVRDDQIIVQNFNQTIG
LNDPTAHAEILVLRSAALKLGNYRLVNTKLYVTLEPCIMCLGGLIQARVP
ELVYACDDSRVGAFSREKLHHNKNINHNLGVTAGVMADECSKLLKDFFKQ
RRN
>FTT0939c add, adenosine deaminase
MLNEKLLLRPKAELHLHIEGTIEPEMMFQLAQRNNVKLKYNSIKEISKAY
VFNNLQNFLDLYYQGVSVLITEQDFYDITYSYLVKAHKDNVTHTEIFIDP
QVHSERGISLSVIFNGVTQAIREAEKNFGIKTSVIVCFLLHLSQDHALRY
FEKLMDFHDRFIGIGLDGYEFGNPPSKFKKLFEIAKKEGLYLTTHVSEPV
EYIWEAIDVLGVNRIDHGNSILEDETLIQRVIKDNIPLTMCPLSDKFLKT
NSNLSSRPVGILLEKGVKVTINSDDPAYFSGYINENYRQISQALKLSEDQ
IIKLINNSLESKFI
>FTT1161 adk, adenylate kinase
MRIILLGAPGAGKGTQAKIIEQKYNIAHISTGDMIRETIKSGSALGQELK
KVLDAGELVSDEFIIKIVKDRISKNDCNNGFLLDGVPRTIPQAQELDKLG
VNIDYIVEVDVADNLLIERITGRRIHPASGRTYHTKFNPPKVADKDDVTG
EPLITRTDDNEDTVKQRLSVYHAQTAKLIDFYRNFSSTNTKIPKYIKING
DQAVEKVSQDIFDQLNKR
>FTT0078 apt, adenine phosphoribosyltransferase
MNLDFIKSKIAAVPDFPKPGIMFRDITPLLADPQGLRKTAEAMAQELKNK
GIQPTIVAGTESRGFIFGVALAEVLGLGFVPVRKPGKLPRATYSVKYDLE
YGSDSLEIHQDAFKVTDEVLVVDDLLATGGTAKATVDLIEKTQAKVAGLI
FVMELDGLGGREVLAGYNVSALIKF
>FTT1663 carA, Carbamoyl-phosphate synthase small chain
MILANDMTNAILVFPDGTYYLGRSIGVRGWTDGEICFNTSMTGYQETLTD
PSYAGQIITFTFPHIGNVGINNEDNESLGVFAKGLIVRENLTNPSNFRAK
KHIDTWLKNRNIVGICGVDTRAIVRKVRKEGAVRVAILSVKPGEFLDANY
VRSRIKNKSNLNGRDLAISVTTNREYDWNEHTFTLGQQVYKQQQSYKYSV
VVIDYGVKYNILRNLVDAGFKVTVVPADSTYEDIMKHNPDGVFLSNGPGD
PFATSDYTMPVIKKLLEVKMPIFGICLGNQLLALAAGLKTKKMHKGHRGV
NQPVLDANTKKVLITSQNHGFVVCDDNVPDNIQIHMSSLFDGTVEGLRFK
DRPAFAVQYHPESSPGPHDCKYLFNEFAEMIAESKKGN
>FTT1664 carB, Carbamoyl-phosphate synthase large chain
MPKRTDIKSILVLGAGPIVIGQACEFDYSGTQACKVLKEDGYTVFLVNSN
PATIMTDPTTTDKIFIEPITVESVGKIIARERPDAILPTVGGQTALNCAL
ALDKAGILEKYNVEMLGAKADSIDKAENRERFNKAMAKIGLEVPRNVVVQ
SLEQAYKALEDIGLPAIIRPSFTLGGSGGGIAYTKEEFEKIVKNGLSLSP
TNEVLIDESILGWKEYEMEVIRDKADNSIIVCSIENIDPMGIHTGDSITV
APALTLTDKEYQIMRDASIAVLREIGVETGGSNVQFAVNPKDGKLVVIEM
NPRVSRSSALASKATGYPIAKVAARLAVGYTLDEIDNDITKVTPASFEPT
IDYIVTKIPRFTFEKFPTTPSNLSSQMKSVGEAMAIGRSFIESLQKALVS
LETGLTGLDQVEIPGVDESKSLKENKTAILKSLEELSPMRILRVAQALRY
GISQQEIHDACKIDPWFIEQIAIIIDAEERLKKTGLPNSKEEFSVYKNLG
FSDAKIAELVGRTERYIRNFRFGKEIYPTFKRVDTCAAEFESQSSYLYST
YEHYSYEEIVRDCESEISDKKKVIILGGGPNRIGQGIEFDYACVHAAKSL
KEEGIETIMINCNPETVSTDYDTSDKLYFEPLMAENVLNIIKNEMRKGEV
LGVIVQFGGQTPLKLVSALHENNIPILGTDPDKIDLAEDRERFKELLDKV
GLKQPLNTIAYTINELKKKIVNVGYPVVVRPSNVLGGRAMEIIHSQEELD
AYIKTNSKCILEGPILIDKFLEDATELDVDALADGGERVFVAGIMEHIEE
AGIHSGDSACSIPTRSLSNEQIEEVKQATIKLARELNVIGLMNVQFAYQN
GQLYVIEVNPRASRTVPFVAKATGNSIANIATKLMLGKKLSEFILNNPIP
RHFSVKEAVFPFGRFADVDCYLGPEMKSTGEAMGIDRTFGVAFYKAQEMS
FNKLPLKGNILISVSNADKPKIIEPVKELIELGFNIFATKGTERFLKENG
IECKLFDKASDNIGNDQVHSTVKAIEAGEVDLLVNTSIRQELKISLALRR
AAIMSRVSYVTTIGAFEAFVIAVRDMRKINNDFDVKTVKEWINS
>FTT1327 cdd, cytidine deaminase
MTQKQDQQLIEYAKEAFNNAYAPFSGFKVGAALLMKDGNIINSANIETSI
LGLSVCAERNAIFYAYSQGYRKDDIVKIAVVADTEKAISPCGACRQIMSE
HLNLDCPIILTNMSDTDRLDTNTKELLPYIFSL
>FTT0559c cmk, cytidylate kinase
MNNSKIITIDGPSGVGKGTLAKALAKYYDFKLLDSGAIYRLAALHCFKNN
ASLENEDDVCKTLRNLDISFKIEDDLVKAFLSNQDVTKDIRTEQIGMLAS
KVAAYPTVRAILLNKQREFATEQGLVADGRDMGTVVFPQAQYKFFLDAST
EITAKRRYDELKTKGQKPNFEKILADIKQRDFQDRNRKVAPLRPANDAII
VDTSQLFIKEVFDSVIKKITI
>FTT0993c dcd, deoxycytidine triphosphate deaminase
MTIKSDKWIKKMSQEHNMIEPFEAGQVKVINNQKIVSYGTSSYGYDVRCA
DEFKIFTNINSSIVDPKNFNDKNFVDFKGDVCIIPPNSFALARTVEKFKI
PRDTLVVCLGKSTYARCGIIVNVTPLEPEWEGYVTLEFSNTTPLPAKIYA
NEGVAQMLFFQSDEECETSYADKGGKYQGQVGVTLPKC
>FTT0114 deoC, Deoxyribose-phosphate aldolase
MVNQSLGLAMITKQEIVSLIDLTQLGDSDTQVDIVNLCSKARNSLGEVAA
LCVYKQFIPVVKKQLGNNFKVATVVNFPNGDNTIEDVISEVKQALSLGAD
EIDLVIDYKEYLDQGFSEKSCQMMVEVKKLCKDKTFKVIIESGELKTAKL
ITKVCQDVIDAGADFIKTSTGKTSEGATLAAAQVILETIKSSAKRIGFKA
SGGIRNYNQAVAYIELAANILANNFINPQTFRFGVSGLLDNLLNEQQEQI
DDY
>FTT0766 deoD, purine nucleoside phosphorylase
MSLPTPHIETLRKEEFAKTVIMPGDPLRAKYIADNYLENVVRVNAVRNMF
GYTGTYKGKKVSVMGSGMGMPSMGIYAYELFKYYDVDNIIRVGSAGSYKA
EFKVYDVVLIEESYCESNFIEIVTGSKTIDVRSSEELNKELIASAQRQDI
ELKKAKAHCTDVFYRKNSDDYKKIVKKYNCDLVEMETAALFATAAELGKK
ASAVVTISDSFITGESTTAQQREQSFTNMMEVALGTIKEN
>FTT0720c dgt, deoxyguanosinetriphosphate triphosphohydrolase
MAINLYNENDYLRQNNDISKKDNFSPFRRDYARVVHSSSFRRLQAKTQIF
PSFENDFFRNRLTHSLEVAQIAKSIAVKLNAEHELNLDYDLIETAALCHD
IGHPPFGHNGEVALNKKMREFGGFESNAQTLRLISHTAKKDIDQKQSFGL
NLTYRTLAATIKYDCLIPAISDLGYLTKGYYSEEARLVADIKHKLLQSYG
VTSIDGKFKTIECYIMDVADDIAYSTYDVEDALKGGFIDPLSMASIDDRL
LDKVFKAMPSDLEITKGEIRNILKNIFSDYIDFSADSRDIYKLSKNIANN
SLLRTKLTSKLVNSCIQNIELELNQDIPILSKVYLNTTIRKQVEVLKKYI
LFKIIKSPKLNVLRYRGREIISEIFDILISSTPDESLLPDDIGAIFYNTV
SLQAKARIISDNISSMTDRYIIELYNQFKSDPSAMIFKPFS
>FTT0319 dut, dUTP pyrophosphatase (Deoxyuridine 5'-triphosphate nucleotidohydrolase)
MKVELKILNKELIKELPGYATEGSAAIDLRACISESIYLKSGECKLVATG
IAINIANPNYAAMILPRSGLGHKKGLVLGNGTGLIDSDYQGELMVSCFNR
SQETIEIEPLMRFAQLVIVPVVQANFEIVEDFSQQSVRATGGFGHTGV
>FTT1470c gmk, guanylate kinase
MNNYIFIVSAPSGAGKSSLLKAFLATDIGKDNYAVAISHTTREPRVGEIN
SREYYFVTVAEFEQLLSQDGFIEYAKVFKNYYGTSKAELDRLLALGKNII
LEIDWQGAQQTRAIYGDRAKSIFILPPSLDELRKRLEKRNTDSKETIDYR
MEQAQSEISHADEYDYLLVNDDFSQSLEQFCKYFEQNIQS
>FTT1019c guaA, GMP synthase (glutamine-hydrolyzing)
MTDIHNHKILILDFGSQYTQLIARRVREVGVFCEIFPHDVAADFIKNYQA
KGIILSGGPESVYDSDVKAPEIVFELGVPVLGICYGMQTMVMQHGGEVKG
ADQSEFGKAIINILNSTNNIFSNMEHEQLVWMSHSDKVTQTGEHFEIIAS
STNAPVAAVAHKNKPFFGVQFHPETTHTENGKQIIENFVVNICGCDTLWN
IENIIENDIKEIKQKVGTDKVILGLSGGVDSSVVAAILHQAIGDQLTCIF
VDTGLLRLNEGDQVMQVFAEHMDINVIRINAKNRFLDALRGICDPEQKRK
IIGKLFVDIFDEEAAKIENAKWLAQGTIYSDVIESAGNNQSKAHVIKSHH
NVGGLPKEMKLKLLEPLRELFKDEVRKLGLGLGLPYNMLYRHPFPGPGLG
VRILGEIKKEYVETLQKADAIFTEELYKHNLYHDVSQAFGVFLPVKSVGV
VGDQRRYEYVIALRAVVSIDFMTATWANLPYDFLSLVSNRIVNEVKQVSR
VVYDVTGKPPGTIEWE
>FTT1299 hitA, histidine triad (HIT) family protein
MSDCIFCKIITGEIPSKKVYEDENIFAFHDINPAADVHILVIPKKHIASL
NDLTEQDQELMGKFILSIPKVAKLMGLKGFKTIFNTGKEGGQMVFHLHAH
ILGGKIRSKLPE
>FTT0205 hpt, Hypoxanthine-guanine phosphoribosyltransferase
MTYSAENTEVYITSQQLEQAVTRLAEQINQDYSGQQVTLVCVLKGSFMFF
ADLVRKLRIDLRTQFITASSYGSSTKSSGTVTLTETSLKEEYVKDKNIII
IEDIVDTGHTYHKLIEGIGKYNPKTLKFATLLFKPARLERDVKLDYVCFE
IEDKFIVGYGLDFDEKYRELPYIGLIK
>FTT1325c miaE, tRNA-(ms(2)io(6)a)-hydroxylase
MIKQQYADFATIENFLLCETPKQWIHKALANVELMLIDHAHCEMKAASSA
MTYIYKHPDKYDLVTRMSKIAREELVHFEQVMRILKKRDIEYRAITASRY
ASQLIKAARTDKEGRFIDALIIGAYIEARSCERFAKIAPFLDEELQKFYN
GLLESEKRHFTIYLHFAEKYSSVDIGKHIARIGEVEKELILSTDSEFRFH
SGI
>FTT0397 mtn, 5'-methylthioadenosine\S-adenosylhomocysteinenuc leosidase
MRKIAILGAMEIEILPILAKLDNYETIEYANNKYYLANYQDKELVIAYSK
IGKVFSSLTATIMIERFGVEALLFSGVAGGLQDLKVGDMIAATATVQHDV
DITAFGYPYGKIPISEVEIKTSAKLLKQAQNVANELGLNLHTGVIATGDQ
FVHCAERKDFVIKEFDAKAIEMEGASVNLICNEMGVPSLILRSISDTADG
DAPENFDEFAKMAAKRSANFIMQILSNI
>FTT0373c ndk, nucleoside diphosphate kinase
MTKQRTLSIIKPDAVEKNVIGEIYSRFEKAGLRIIAAKMKHLSKAEAERF
YAVHKDRPFFSALVEFMISGPVMIQVLEGENAIAKNRELMGATNPKEAKA
GTIRADFADSIDANAVHGSDAEDTAAQEIRYFFSDTEIFG
>FTT0534c nrdA, Ribonucleoside-diphosphate reductase, alpha subunit
MSNQSYLGINIDLSRDRELSEQAQQLLTNYYCLQNEPSPQYAFARAAVAY
SFGDMNLAHRIYDAAAKGWFMFASPVLSNAPLPGVKVKSLPISCFLSYVP
DSLEGLIEHSSELRWLSVKGGGVGGHWSSVRAVSDKAPGPIPFMHTVDAD
MVAYRQGKTRKGSYAAYMDISHPDIIEFLGIRVPTGDVNRKCLNLHHAVN
LTDDFMQAVANDQDWKLIDPDDKTVRDVIKARKIWETILETRYRTGEPYL
NFIDTANRALPKSQKDLGLTIKGSNLCNEIHLVTDEKRTAVCCLSSVNLE
RYDEWKDTSLIKDLIRFLDNVLQFFIDHAGDEISKARYSASRERSLGLGA
MGFHSYLQLHRVPFESQRAKEINEEIFKRIKEQALEETLILGAEKGEAPD
MAGTGRRNAHLLAIAPNANSSLILNTSPSIEPWKANAFTSRTRVGSHLNK
NKYLEQELEKIGKNTEEVWSDIITNGGSVQQLDFLSKELKEVFKTAIEMD
QDWLVYLGGERQKYLCQGQSLNVFFPAGASRGYLHKVHFNAWKYGCKGLY
YLRTETSNRAENISKKVEKKRLVEFSEIKQSENECIACEG
>FTT0116 nupC, nucleoside permease NUP family protein
MFVKILYLLLGLVTVFILAFIWSSDRKKIKYKHLFIILFFQLLVCFFILQ
SSEGIKLVAIISTGFDKILQHAHEGTAFVFGSLADTSKNGFVFFFNVGMP
IVLISGIIGVLQYFRILPLVIRWVGFILTKITGMGKLESFNAVSSLTVGQ
QENFLIYKKIIGHLPANVLYTMAATAMSTVSLAIAGSYMSIIEPKYVCTA
IVLNMLSTFFVLHIINPYDKDPSLNYDTLHADYETGRQSFFEMLSEYLLD
GFKIAVIVCAMLVGFIALLNLVDGIFQEILGITFRQILGYIFYPIAWVLN
IHGNEIFLSSQIMGTKIVTNEFVAMQELAKNSQQLSEHTKAVVSVFLVSF
ANFSSIGIIVGAVQALNKEASIKVARFSLKILYGAVLVSILSACVVGFIV
>FTT0115 nupC1, nucleoside permease NUP family protein
MIIKSLYFILGLIVIYFLAYIWSNNRRNIRYKNLIIILIVQLILAKFMLS
TSIGINIINYVNKCFEVLLDSTHIGVEFVFGNLANIKEFIFFFNAAMPIV
VMSAVIGILQYFRILQFLVFAIGSILSKVTGMGKLESFNAVSSLSVGQSE
NFLYYKKIIKYLPSNVLYTMAATAMSTVSIGTAAAYMTIIDPSYVCVAIV
MNMFGAFFVLNIINPYEKTKEVTYEFLTDQVEDYERQRFFEMLSEYILDG
FKVAIIVCVMIMGYIAFLNLADGIFSSLVGISLRDILGYIFYPIAWILNI
HGNEIFLSSQIMGTKIVTNEFVAMQELANHSTQLSQHTKAVVSVFLVSFA
NFSSIGIIIGAIQALSREASVKVARFSLKILYGAVLVSFLSANIVGFIL
>FTT1444c ppx, Exopolyphosphatase
MFYMSKIVATVDLGSNSFHMLISEIKPDGEVVTLSKQKHKVQLRAGLNNN
LTISKDAQERAIECLEFFAQEIQKYKVEYVRAVGTYTLRKAKNNIKGFKK
KLDKALGTKIKIISGLEEARLVYVGARDNHDIKQKTLVIDIGGGSTEFVI
GRGNKILIARSLDMGCVGMQKDFFANEKLDFANFHAAAAKAREIIAPILY
RYKRIGWSTVLGSSGTIISVTNICQKLTGNSVITKDFLNDLITMMMDKRE
VEHICFEGLREDRESVLAGGVVILYAIFDCLGISEMRLSNGAVREGMLYE
LVKSKYKIIIN
>FTT0674 prsA, Ribose-phosphate pyrophosphokinase
MSEDLMIFSGNASKKLASEVAKELGATLGNATVDRFKDGEIHVVLNENVR
GKDVFVIQSTCPPSDNLMELILLIDALKRSSAERVTAVLPYFGYARQDRR
SKSARVPISAKVVANLLQAVGLDRILSVDIHAEQIQGFFDIPFDNAFATK
IFLEYVRKNPEKYQNIKIVSPDMGGVVRARSVAKNLGVEIAVVDKRRPKP
NVAEVMNIIGEVDGKHCILVDDIMDTGGTMCQAAKALIEKGGAAKVSAFC
IHPLLSGDAIKNIEDSAIDELIVTDSIPLKPHAEACSKIKVITLAPLLAQ
IVEKTNGEESVSDIFRIDGLVD
>FTT0204 purA, adenylosuccinate synthetase
MSNIVIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKT
FLHLIPSGVLRQHTKCVIGHGVVLDPVALDEEITRLQAKGIAISAENLFV
SESCTIITSYHKLLDAVRESNTSEKIGTTGKGIGPAYEDKVSRKGIKFKH
LFDKDLLRSRLAISLAEKETLFRDLYKVEYPTLEQEFDKLFALGQKLKQY
AADTFSIIDQAIAAGKNVVYEGAQGVLLDVDYGTYPFVTSSNTSVAGVYS
GATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVT
TGRIRRCGWLDLPLLKYSAKCSNLTSIALTKVDVLSDMDTLKVCIGYKYE
GKEIYCAYPGIDLYKVEPILVEMEPFSIDETVTKDNMPAALKTYLKTIEN
HVGIPISSLAYGPSREQILFFEDYFKKG
>FTT0015 purB, adenylosuccinate lyase
MIKRYDVAEISKIWADENKYAKMLEVELAILEALEDRMVPKGTAAEIRAR
AQIRPERVDEIEKVTKHDIIAFCTSIAEQFTAETGKFFHFGVTSSDIIDS
ALSLQIRDSMSYVIKDLEALCDSLLTKAEETKEIITMGRSHGMFAEPMSF
GQKFLGAYVEFKRRLKDLKDFQKDGLTVQFSGAVGNYCILTTEDEKKAAD
ILGLPVEEVSTQVIPRDRIAKLISIHGLIASAIERLAVEIRHLHRSDVFE
VYEGFSKGQKGSSTMPHKKNPISTENLTGMARMLRSHVSIALENCVLWHE
RDISHSSAERFYLPDNFGIMVYALRRMKNTIDNLVVQRDIIEDRVRSTSA
YLSSFYLHFLVANTPFMREDCYKIVQQVAFDLKQGESFSKKLQKVMHDEH
NIILDIPEMDFEGIKKTYLKEIDHVFDRSVKA
>FTT0894 purCD, Fusion protein PurC/PurD
MLDKQIIANNIKNVLKSTNLDIKNKYIGKVRDMYFTDDKSILISTDRQSA
FDRSLGFIPFKGQILAQSSVWWFKETAHIVKNHFIDSPDPNVVIARKAKV
LPIEFVVRGYITGSTSTSLWTHYKNGSRDYCGNILPEGLKKNQKLPQNIL
TPTTKEQDHDRPISAEDIVKEGWLTQQQWDFASQKALELFEFGQKKALEH
GLILADTKYEFGIDEQTGEIILIDEIHTPDSSRFWLKDSYATRFENGEEP
ENIDKEFFRLWFAKNCDPYNDEVLPQAPQELVVELSQKYIALFEMITGQK
FEVPRDLENINQRIVKNVTDYLNMEKPVNILLVGSGSREHAIAEAVKRSS
IANKLFCISTAINPAIDKITQGYQIADICNCDEVLEYAKSQSIDIAIIGP
EAPLEAGLADALKTAAIGVVGPTKKLAQLETSKGFTRDLIRDYDIGANPF
FRKFNSMDGVEETLKKYQNQFVIKADGLCGGKGVLVWGDHLHSLDEAIRH
CQSLVDAGKEFVIEEKLVGQEFSLISFADGKNFIHMPAVQDHKRAHEGDK
GPNTGGMGTYSDANHSLPFLSAADIERAKQINEKVVRALADKFGEPYQGI
LYGGFMATKDDTKVIEYNARFGDPEAMNLLTLLETDFVEIAQAITQGKLD
TVKAKFKNQASVCKYLVPLGYPNQSVKNFEIDISQCPDNVELFLGAVDYK
DGKLIGTGSRAIAVLGLGDTIAEAEQKAENAVKNIYGKLFHRPDIGTKEL
INKRIKHMNLLRGDKYQELK
>FTT0896 purE, phosphoribosylaminoimidazole carboxylase,catalyic subunit
MSVQVGVIMGSKSDWSTMKECCDILDNLGIGYECEVVSAHRTPDKMFDYA
ETAKERGLKVIIAGAGGAAHLPGMVAAKTTLPVLGVPVKSSTLNGQDSLL
SIVQMPAGIPVATFAIGMAGAKNAALFAASILQHTDINIAKALAEFRAEQ
TRFVLENPDPREH
>FTT1721c purF, Amidophosphoribosyltransferase
MCGVIGVAGPDQVSYALFYGLSLLQHRGQDAAGIATMDHGHFFIRKNTGL
VSDVFTDEKLEKSKGNMGIGHVRYPTAGSLGAADSQPFYVNNPHGIVFVH
NGNLTNVPELAQMLHDIERRHLNTSSDSELLLNFFACGMNKSKGSATSEA
VYKACKFVFEHVKGGYACTAMIANFGLIAFRDPYGIRPLVLGFKEYDDGE
KAYMVASESVALDISGFKVLRDVEPGEVIIITEDRKVHSKICAKNPVLAP
CLFEYVYFARPDSIMNGVSVYQARVDAGKILSKRIKEAWKDKDIDIVIPV
PETGRASAQEIATALGVEYREGFVKNRYVGRTFIMPENVDRKNFVRRKLN
PIPAEFRDKNVLLVDDSIVRGTTSKRIIEMIRDLGAKSVYLASVSPAVRY
PNVYGIDMPVKSDLIAHGKTIEEIRQWIGVDGLIYLPLEDLKEIIQKQNP
KIREFEDSVFSGNYITGDVDDAYLDALEKHRKELKELEKKYKGFDN
>FTT0203c purH, bifunctional purine biosynthesis protein
MSKIKRVLISVSDKTGIIEFAKELSKYNIEILSTGGTSKTLKDAGINVID
VSEHTQFPEIMNGRVKTLHPLIHGGILADRDNPEHLDAMLKNHIGQIDMV
VVNLYPFVNTVKSGADFDTCIENIDIGGPSMVRSCAKNHKHTTIVTNPSQ
YDLVIKEMAENDGKTTLATRREFAKEAFAHTAEYDSHIANWFSKELDEEY
PEKLFSVGTLKQVLRYGENPHQKAAVYSTDADCVSITNARQLQGKELSYN
NLNDADGAFEMVCEYSEPSCAIIKHANPCGIASGKNAFEAWTKALACDPI
SAFGGIVAFNCEVDKEFAESLGKMFLEVIIAPSYTQEALDILAAKKNLRV
LETGKVFDTKSSRMISKNIHGGILSQSYDNGGVDINDCKVVTDRAPTDKE
WADLMFAWKAVKYVKSNAIVYARDTQTVGIGAGQMSRVDSARIGAEKAQA
HQGAKGSAVASDAFFPFADGLEECIKAGATAVIQPGGSKNDQEVIDAANK
AGITMVFTNMRHFRH
>FTT0897 purK, phosphoribosylaminoimidazole carboxylase, ATPase subunit
MKIGIIGAGQLARMLSLAGTPLGLEFHCLGKNGDCAEEVVKTVTDIELTK
VNDVVAWAKQFDVITFENENISHELIKAINHEVSVYPSAKAIAISQDRLL
EKSFMQDHGIATAKFVNIDSLAKLQSAVDDHGLPAILKTRRFGYDGKGQF
VIRSQEDITKAWDVLKDAPDGLIYEAFVDFDYEVSQICTADLKGNIAFYP
LARNTHKQGIIVESEAPFENVVLAEKAQQIAKILVKEFAYVGTLAIEFFV
KGDELIVNEIAPRVHNSGHWSIDGAVTSQFENHVRAIAGLILGDTTSRKT
VMLNCIGGMPATKDLAALDRVKIHSYNKEPRKGRKVGHLNLNLNDETDEY
QLLQVKKLIALSEEI
>FTT1720c purL, phosphoribosylformylglycinamidine synthase
MITIFEGLSALSPFKREKILAAAKKISNKVESVSAQYIHVTELESELNSE
QERIVKSLLNYNREYGIAQPMGHTFIIAPRVGTISPWSSKATDIIKNTGI
KAVKRIERAILFGVEGQVSASELKQIQDIVHDRMVEEVFSCKDDLYRLFS
VTAPKELEFVNVLEKGAQAIKEADRKLGLALSEQEIEYLADEYTKLGRNP
TDTELYMFAQANSEHCRHKIFNAKWTIDGQEQDKSLFKMIRNTTEKSPQG
VLSAYKDNAAVIEGATAQRFYPNTQTGVYSFNQEEVDILMKVETHNHPTA
IAPFSGSATGVGGEIRDEGATGLGAKPKAGLTGFTVSNLNIPGFEQAWET
SKYGKPNHIVTPLQIMLEAPIGGAHYSNEFGRPNLNGYFRTYEQEVNTSA
GKEMFGYHKPIMIAGGMGNIKRMHVEKGVIKVGAKLICLGGPAMRIGLGG
GAASSVVSSDTNSELDFASVQRDNAEMERRCQEVIDRCWQMGENNPITFI
HDVGAGGISNAFPELVKDGGVGGYFELRKVNVGEEGLSPLEIWSNESQER
YVLSVDPESLELFEQLCNRERCPFAVVGEAISEKHITLNDEYFDNKPVDL
PMGLLFGNTPQMHIDVKTVKVEQQAFDTSAIKLDEAIERVLKVPAVASKS
FLITIGDRSITGMVARDQMVGPWQVPVADCAVTTATVDSQAGEAMAMGER
TPVAAINAAASGRLAIAETVTNLLAADIEKLSDIRLSANWMVAANQGDEN
QKLYETVRAVGMEFAPELGIAIPVGKDSMSMKTKWSDNGQAKSVTSPLSL
VISGFSPVTNARKTLTPVLVDDNDTTLLHIDLSNGAGRLGASCLAQAYNQ
VGNVAPDIEASKVKVLFENITKLKAENKILAYHDVSDGGVFATLAEMSFA
GRKGLDVKLQTQDVLAKLFAEEVGVVIQVRNSDVSLVEEMFKDTQIHLCA
IAKLNSSDELNIFANGEKIYSNTRVNLQRWWAETSYQIQSIRDNSECAKQ
EFDSILNTNDKGIHVEATFDLEEDITAKFVNVEKPKVTILREQGVNGQVE
MAAAFTTAGFEAHDVHMSDLHAGRVTLADFKVLVACGGFSYGDVLGAGGG
WAKNILFTEKLRDEFSRFFGRDDTLALGVCNGCQMLAQLKSLIKGAENWP
IFIKNKSEQFEARVSMVEIQESDSIWFADMACTKAPIAVAHGEGRPLFEN
DNQQQAMLASAQVALKYIDGQGQATEMYPYNPNGAVNGLTAVTALDGRVL
AMMPHPERVYRAITNSHIPAEYDEYSVWMRMFRNARKWVG
>FTT0893 purM, Phosphoribosylaminoimidazol (AIR) synthetase
MAGLKYEDAGVNIEAGNQAVERMKQHVKKTFTQDVLTGLGSFGSLYSLKN
IINNYDDPVLVQSIDGVGTKTKVAVMCGKFENLGYDLFSAATNDIVVMGA
KPITFLDYVAHDKLDPAIMEELVKGMSKACAECGVSLVGGETAEMPGVYQ
AGEIDMVGVITGIVDRKRIINGENIKEGDIVFGLSSSGLHTNGYSFARKL
FFDVAGNKHTDTYPELEGKTIGDVLLEPHINYTNIIHDFLDNGVDIKGMA
HITGGGFIENIPRVLPQGLGAQIDKDSFATPAIFKLMQRIGDISEFEMYR
SFNMGIGMTIIASQDQFDKMQELAKKHTNTKLYQIGKITNSGKVEII
>FTT0895 purN, phosphoribosylglycinamide formyltransferase
MSKLNLVILGSTRGTNMQAIIDAIANKQLNAQISLVISNKSDAYILQRAA
DYNIPTKYIAAKGLTREQYDELVVAEIQKYNPDLILLIGFMRILSSVFIK
AFEGKILNIHPSLLPKHRGLMDLAVHQSVIDAGDSISGCTIHQVSEEVDG
GDIVLQLKCDVVKEDTADSLKEKVQALESKAWIEVIKNWDK
>FTT1767c purT, phosphoribosylglycinamide formyltransferase 2
MNISNIKIMLLGSGELGKEFIIAAQRLGIHTIVVDRYKNAPAMQVAHESY
VIDMLNSDALEQLILAKNPTYIVPEIEAINTDSLVKLEAHNFNIIPCAKA
AKLTMDRQGIRALAAQQLNLQTSKFAFANSEQEYLDVIQSIGLPFVIKPV
MSSSGKGQSIVKEHNEIKKAWDYAQNGSRGHAKGVIVEQFIDFDYEITLL
TVRHKDGTSFCDPIGHIQKDGDYRFSWQPHTMPDTALAKSQEIAKEITDA
LGGYGVFGVELFIKGDEVFFNEVSPRPHDTGMVTLISQNINEFELHLRAI
VGLPIPDIQTLQPSASAAILLEGDTANASICGIDKALADANVDIRIFGKK
EIHGKRRMGVVLAKAQNTHIALETSKQALAHIHLTK
>FTT1665 pyrB, aspartate carbamoyltransferase,
MLSFQKLLRGDQITKDDLFKLFHQADIYKNKLANSEPIKDLEGKILASLF
FEPSTRTRFSFESAMNRLGGKVISLENGSSSSTQKGETLDDTGRMIDQYA
DIIVMRHPKPHSVEEFSKYVNSPVINAGDGENEHPTQSLVDLYTIYSEKG
SLDNLKVGFLGDLKYGRTVHSLTNILAKYNASFKFISSKELQIPKKLKDF
IIKNGNSFIELDKVSADVLEDLDVLYVTRVQRERFPDEESYLKNKDLCYL
DRKHISPRSNFIILHPLPRVDEMDRSIDELECAKYFEQIKYSIPIRMTLL
ALLVIS
>FTT1660c pyrC, Dihydroorotase
MSNQSLLIKNATVVNEGKTFKSDVLVENGRIAKVAANIDKSADKILDATG
FHLLPGMIDDQVHFREPGLMHKGDIESESRAAVMGGITSYMEMPNVNPAT
TVVERLDEKKERAATRSHANYAFYLGATNDNVEELKRLKPNDACAIKIFM
GASTGNMLVNNPETLEGFFRDSPLLIVTHCEDTPMITELENKARQKYGEN
VPFDLHPEIRSREACFKSSDLAVSLAKKYNSRLHVLHLTTAEEMVHFNNT
IPLEEKRITAEVCAHHLFFSRKDYADKGSRIKCNPAIKEESDRLKLLECV
ANDTIDVIATDHAPHTWEEKQGTYFKTPAGLPLVEQALISILEHYHKGFL
TLEQVVQKTAHAPAIVYKVKERGFIREGYHADLVLVDLNDPHTVTDECCH
YKCGWTPFDGITFQSKVQTTIVNGVVKYHKGKIVSDQRGQCLEFNHEF
>FTT1647c pyrD, diyroorotate dehydrogenase
MQNQDLKRIIISPPFGKYLKFKETSNVYGSFTVNRRWGLIKQAIKTIRKI
DKNAWRNKIGLRNPGLANTNPPKRAQDIISLAALDMSDWHSFAETLKLPK
FAQHRNIEINIGCPNASIVDFPAELAPLFEDRNISIKMPPTVDHNAKIRE
YLAVGITTFHLCNTIPTAKGGISGYPLHKYSLPAIKKARQEFGDSITIIG
GGGIYTLDDAKKYIEAGADHLSLSSIMFNPIRGKKLVKEIVKFWLDDF
>FTT0437c pyrE, orotate phosphoribosyltransferase
MFIEFALKNQVLKFGEFTLKSGRISPYFFNAGLFNTGAQLATLADYYAQL
IIKSDVKYDILFGPAYKGIPLVAAISTVLALKYNIDMPYAFDRKEAKDHG
EGGVFVGADMTNKKVLLIDDVMTAGTAFYESYNKLKIINAKIAGVVLSID
RQEKAKDSDISATKKISQDFNIPVLAVTNFESIFEYVKENLDETMIDKFK
QYRQKYGS
>FTT1648c pyrF, Orotidine 5'-phosphate decarboxylase
MRNSMKIMFSADGISKSDLEKTAAVSKYVDCVKIGHILCSTLSFKEIHEL
VGDKDIFLDFKLHDIPNTVKTAIENYSKAIPNFKYFTFHGTASDEMIKAA
LTADTQAIPLAVITLSSDANFDKADSLAKFQRCVDLGVENFICHPHLVAD
VRAKFGDKIKLYVPGVRLESDLSDDHFNALTPKKAKELGVDYIIVGRPLL
RAENIVEKLKEFEC
>FTT0374c pyrG, CTP synthase
MNSNTKIIFVTGGVVSSLGKGVTAASLATLLESRGLNVTMMKLDPYINVD
PGTMSPLQHGEVFVTEDGAETDLDLGHYERFIRNKMTQANNFTTGKVYQS
VLRRERKGDYLGATIQVIPHITDEIKRRICSGIADDVDVAIVEIGGTVGD
IESQPFLEAIRQLRIELGRNRTLFVHLTLLPYIKVAGEIKTKPTQHSVKE
LRGIGIQADVLVCRCEKKFDDSEKRKIALFTNVDQDCIFTAEDVDTIYEV
PLKYNQQGFDAKLVELLNLNAKEADLSEWQNVVNTIRDVKGEVTIAMVGK
YVSLTEAYKSLNEALYNAGYKKGVKVKIKFVDSEDVNENNVESYFKDVAA
ILVPGGFGSRGVEGKIISIKYARENQIPFLGICLGMQLAVIEYARNILGI
KDAHSSELEPTTANPVIGLITEWQAEDGTVHQRTHSSDLGGTMRLGGYKC
VLKQGSRAREIYQADEVVERHRHRYEVNSNYVERLEEAGLIFSGRSEDNK
LMELIEIPQHKWFIACQAHPEFTSTPRYGHKLFESYIQAAIENSNN
>FTT0315 pyrH, uridylate kinase
MSNDSSECSQKLPKLKRILLKLSGESLSADQGFGINVESAQPIINQIKTL
TNFGVELALVVGGGNILRGGRANFGNKIRRATADSMGMIATMINALALRD
MLISEGVDAEVFSAKGVDGLLKVASAHEFNQELAKGRVLIFAGGTGNPFV
TTDTTASLRAVEIGADALLKATTVNGVYDKDPNKYSDAKRFDKVTFSEVV
SKELNVMDLGAFTQCRDFGIPIYVFDLTQPNALVDAVLDSKYGTWVTLD
>FTT0621 tdk, thymidine kinase
MAKLYFRYSAMDAGKTLDLLKVAYNYEDRGRKPLVLTSAIDKRAGLNKVK
SRIGINQDAYSLTDRDNIFEFVENYNSSNKIDCVLIDEIHFFTQEQVWQL
AEIVDELNIPVICYGLRTNYLGQPFETAALLLAIADTLEEVKTICHCGKK
ASFNMMVQNGKAIKQGNPIVVDDDSLKEIDTKYVSVCRKHWKEGVYE
>FTT1229 thyA, thymidylate synthase
MQEYLNFLKYIKENGVLKGDRTGTGTRSIFGYQMRFDLQKGFPLVTTKKI
HIPSVVHELLWFLSGSTNIKYLNDNNVRIWNEWATVDGELGPIYGKQWRD
FNGQGIDQIADVIQMLKTNPNSRRILVSAWNPCVVPSEKISPQENVVKGN
SALPPCHAMFQFYVANNKLSCMLTQRSADAFLGVPFNIASYSLLTNMVAQ
QCNLDVGEFIWSGGDCHIYNNHIEQVNEQLSREPLALPTLKILRKPNSIF
DYKYEDFEFENYNHHPAIKAKISV
>FTT0117 tmk, thymidylate kinase
MQSKFIVIEGLDGAGKSTAISFVRKYLEKNNLAAIYTREPGGTKIAEELR
NLVLHNKYDEEIHSDSELLMIYAGRVQHYRNLIAPALEKGINVVSDRFYW
SSMAYQGGGRGVELSKIRALNDNFLNGCEPDLVIYLDIDPILGLQRAQKV
GSPDRIEKAGLEFFNRTRKVFKDLVKDSDNAIEIDAAKSIQEVEKQIYLI
LDKHFNFQN
>FTT0702 udk, uridine kinase
MAGKGDVFIIGIVGGSGSGKTLFSNAIIKKLKSKHLNKIAVISEDRYYKN
WGEMVGFEEACKINYDHPDAFDHKLLRKDLNNLVQGNDIYIPHYDYTTHS
RVEEKAEKITGGVSVIILEGIMLFNDRKLLKMMDFKVYMDTPADLCFIRR
LMRDQNERGRSVESVINQYLETVRPMHIKFIEPSKRKADIIIPDGAQNKT
VIDIIYNKVRQLLKKNGVKNG
>FTT1326 udp, uridine phosphorylase
MSNINIANKRVAKSDVLYHIALSEEMINSATIAILPGDPKRSEYLAKMLD
TDATFLASNREYTSYLAKVANQNVIVISTGMGGPSVAICIEELAMIGVKK
FIRVGTCGAIQENIEIGDLILSTASVRLDGTSYHYAPIEYPAVASFSLNT
SLYRSAQTLNKKIHCGITGSSDTFFPGQDRKDNYSGYIRRHFINSLNEWR
KLNVLNFEMESSALFTVCATFGLEASCLCTVLAKRTTSEYIDKSKYDEGM
YNIMMIIKHSIENNFFS
>FTT0716 upp, uracil phosphoribosyltransferase
MFWRVMKVVEISHPMVKHKLGLMRAASISTQEFRRLTKEITSLLTYEVTA
GFELEKTEILGWQGENIEIDQIKGKKLTVVPILRAGLGMMDGVFEHVPAA
KVSMVGMYRDEKTAKPVAYFAKLCDKLDERVALIVDPMLATGGSMIATVS
LLKKAGSKDIKIITLVSAPEGIDALAKAHPDVELYTASIDSHLNDKKYII
PGLGDAGDKIFGTK