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# IncP-1beta multiresistance plasmid pB8

>pB8_006 hypothetical protein
MSKQAVFTMKLEPELRAEFMAEAEAAHRPASQVLRELMREFVQRQRESRE
YDEFLRRKVEAGRASMRAGLGRSNDEVEAEFAARRASVASQA
>pB8_008 putative transcriptional regulator
MKNGVRRPKRPELVKALLLDAGAQLLVHGEQLSIGAVAEIADVTKGAVQH
HFPTREALVMALYDHLVAEFQDRVADDGSGEPAAWRYARLALESADEASS
DHGKALLAACVVERSVSTNWAQWVRDDRALDGSDTNKLLARLAADGLWLS
EVLGIYELSAAEREALSISIKKLTQGS
>pB8_002 putative polyketide cyclase
MNRRTKLLAALSGAALAVSAAYAQDPKDVPQKTGVTPNDLVVRGVDGAEN
LEFIVIDVKYEPGGINRRHYHPAAVTFYVLSGTPVFQEEGKEPVTLKPGD
SLLVPAGTTHSHWNPSRTQGVRWLEFIVAERGKGKSIRKP
>pB8_036 putative acetyltransferase
MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARIDRTFAE
TFVLRSELLVASCSDGIVGCCTLSAEDPEFWPDALKGEAAYLHKLAVRRT
HAGRGVSSALIEACRHAARTQGCAKLRLDCHPNLRGLYERLGFTHVDTFN
PGWDPTFIAERLELEI
>pB8_001 'merR, MerC protein (truncated)
MREKMADLARMEAVLSELVCACHARRGNVSCPLIASLQGGASLAGSAMP
>pB8_033 aadA4, aminoglycoside adenylyltransferase
MGEFFPAQVFKQLSHTRAVIERHLAATLDTIHLFGSAIDGGLKPDSDIDL
LVTVSAAPNDSLRQALMLDLLKVSSPPGDGGTWRPLELTVVARSEVVPWR
YPARRELQFGEWLRHDILSGTFEPAVLDHDLAILLTKARQHSLALLGPSA
ATFFEPVPKEHFSKALFDTIAQWNAESDWKGDERNVVLALARIWYSASTG
LIAPKDVAAAWVSERLPAEHRPLICKARAAYLGGEDDDLAMRVEETAAFV
RYAKATIERILR
>pB8_053 incC2, IncC2 protein
MKTLVTAIQKGGQGKTFATCHLAFDFLERGLRVAVIDLDTQGNASFTLSA
YQSGYLASQLFTGDTDDLRYWFGKREGESLALIAADANLANLDKMELSQA
AAALRASVAALGEFFDVCLIDTAPSLGVAMTAAVLTADYMLSPIEMEAYS
LQGMKKMVAVISNLRKQNPKLRFLGMVPNKVDARKPRHVNNLATLQQAYP
QLILPFSIGARDSIAEALGEQMPVWKIKKTAARKATQEVRALADYVFTKM
EIAQ
>pB8_031 intI1, integrase
MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVHWVRAFIRFHGV
RHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPW
LQEIGRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEG
LQLRVKDLDFDHGTIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWL
KDQAEGRSGVALPDALERKYPRAGHSWPWFWVFAQHTHSTDPRSGVVRRH
HMYDQTFQRAFKRAVEQAGITKPATPHTLRHSFATALLRSGYDIRTVQDL
LGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLTSER
>pB8_051 kfrA, KfrA protein
MAISKEQIFAVADELDAAGQNPTLANVRKQLGSGSFTTISEAMNEWRARK
ASQAAPIREPAPQAITDKLAELGGDLWAVALEMANNRLAAEREALEAVRQ
ETEAARQEAAELADQLTGELDEAKARVAALEAVEAAAKGEADELRGKLAA
TSERAATAEARAGELRTELDHAHQEARQARAERDKAQERATASADQVEAL
RADLAAANSRTAEIERRAGELRADLERANQATDQARAAQAEQRKATEVAA
AERDQVRAELVKVQAKAEAAEQAHQEQRKAMAAEAHRQAERLTAAQGERD
QAKRDAAQAREEAAGLRGRLEALETVMAQGRAADPTSGGRKKT
>pB8_050 kfrB, KfrB protein
MKERLLVMNGQRIVQAEKDGAWTNQKVDKAGALKPGIYNLYTAQAADKKQ
THAGVIVHADATNVYQQIGKNFVMHARSDFDKVPEIGSAKSISYNAQGKA
AVAAEAPKLTRGRSM
>pB8_049 kfrC, KfrC protein
MKRLTIPGSGTESRATKPARVSAPATLGGAAFGASREDTGADLLEAAQAA
EIEQQATLEAAPVEQSYPETLALYVQAKHDQVEHIEDRLENLIDRQQARL
QQTQASAPGRLSLPGSKRAWQNQQAQQQARLQTLHARLEAVREIKEGMGL
HSPKIEELATRKMRAENPELASDWDAMREAARRHELLMRKQEQERKQSQA
QERPGRSQSLGLSARPA
>pB8_062 klcA, KlcA protein
MNTQDQPVTASLVAEAQRLDFLPTYFGPRLMMRGEALVYAWLRRLCERYN
GAYWHYYTLSDGGFYLAPDLAERLEIEVDGNGFRGELSADAAGIVATLFA
LGQLAAEIAGTDAADALIDRYHFLRGFAAGHPEAAAIYRAID
>pB8_061 klcB, KlcB protein
MAKRTKQPAQTGQDWSAPAAELLAELPADRDGLLAAAVAAVVEIDAAVMR
GDGAAAELAGDRYEAIIWKLNGGTNFGCMADDEAAGRVIERHCAAVPGDV
PLWGQRGQFLAVAGDVRALVEYEAGYGGPLNAHFQFHAVDLDRPFISATG
YRSHFDTARGCMTVDEVARGILTAMLAEKKRPVLIEANYRDRLADAPLPD
WLAGLVPPARREPATVTIPPGFVLVDVVLPAHKAFIARRWAAEAAGKVKA
ARAARSNAKGKAGGRERDPASAETAMRCSTAKADDCKAEAGPVSPEATMP
GAGEASCSTARNGDAGPADLVEFTPAPGQRCEIVSVHHPVFAKEIGKRVI
IVKVHPDTRQVWAHDDRPVTYKTNRAGRRVVDSDPSCIQSIYGFDQLRLI
T
>pB8_059 kleA, KleA protein
MSKNKIMPWVDALPNVEATDFQARRDQIEATMAEAAELVKQAEELRGKAY
FAALSLEASAKGEWSSQAVEQAKRSVGW
>pB8_058 kleB, KleB protein
MSKGKIEIIETCCRRCGKSIRTLSHTIIGADDAREKFGSICGGCITPEED
NELTEMLLAAAVRRMSGATLQ
>pB8_057 kleE, KleE protein
MSNIVKFPRASKPPAPEPVQPAAPAAAPAAPKAEGRGLVAGLVKFVWVAT
VLVWPVLKWVLAIITFFQFVRMLYHWNTPGVYAGWSFLAYFAALTAITYF
VSIYKPKGL
>pB8_056 kleF, KleF protein
MAKQTLPYPPGFVEPTTGRVAVMVREYADSDLNGDAPAYWYSAQSEEWGL
DPWRLVEGVDPHVGGGSFDVCFASGGTRTVGPLMTFFLSAAHAAQLIDAK
GEELALQRATLAVIADGLGLPAKALRIEAKVEGRPAVFYDQDGATLCACA
VDSDHWRQARATAATASAIDKARTNF
>pB8_055 kleG, KleG protein
MRHSSLTPRGKSWPCSAPPWPSSRTGWACLPRRCASRRRWRAGRPCSTTR
TGPRFARARWIPTTGDRRGRRPQRHRPSTRREQIFSR
>pB8_063 kluA, KluA regulatory protein
MRTTQQLSITLPNDMADVVKTKVKTGEYASESEVIRDGLRALLARDRAVE
SWLHNQVGPAYDALKADPSRAVTADQVRARLAAEHAKAQ
>pB8_064 kluB, plasmid stability protein
MSYAVVFSPEAEEQLAELYRYIAAAASPDVAARYTEAIVTYCESLRTFPL
RGTMRDDVRPGLRITNYRKRAVIAFDVAGDLVSIIGVFYGGQDYETILHD
DADD
>pB8_054 korA, KorA protein
MKKRLTEAQFQTAIKGLEIGQQTIDIARGVLVDGRPQAEFVTSLGLTKGA
VSQAVSRVWAAAGEQLPEGFERVTAVLPEHQAFIVKKWEADAKRKQEPKS
>pB8_052 korB, KorB protein
MSAKTNAKKKEQDKPQSSGLGLDGLGDLAGLLNEQPAANAGGAGPQELPL
DLIDEDPHQPRTADNPGFSPESIAEIGETIKARGVKSPISVRENPDAPGR
YLINHGARRYRGSKWAHKTTIPAFIDNDYNEADQVIENLQRNELTAREIA
DFIGRELAKGKKKGEIAKEIGKSPAFVTQHVTLLDLPEPIAEAFNSGRGK
DVTVINELVTAYKKNPDEVAAWLADDSQELTRGSVKLLREFLEDKRSHED
GDRDPNTVDALTGKTDAEAGDGEQGPQDDDAKGKKEPKEADPDKLKKAII
QVKHDDRPARLILNRRPPAEGWAWLKYEDDGQEFEADLGTVQLVALLEG
>pB8_060 korC, KorC protein
MTNDANIRLECLKPAERWAQPSGEEVREVLRLAGLTGGKAAKVLGLGPKG
DRTIRRWVGEDTPIPYAAWALLCDYAGLGLIWKEV
>pB8_032 oxa-2, Oxa-2 beta-lactamase precursor
MAIRIFAILFSIFSLATFAHAQEGTLERSDWRKFFSEFQAKGTIVVADER
QADRAMLVFDPVRSKKRYSPASTFKIPHTLFALDAGAVRDEFQIFRWDGV
NRGFAGHNQDQDLRSAMRNSTVWVYELFAKEIGDDKARRYLKKIDYGNAD
PSTSNGDYWIEGSLAISAQEQIAFLRKLYRNELPFRVEHQRLVKDLMIVE
AGRNWILRAKTGWEGRMGWWVGWVEWPTGSVFFALNIDTPNRMDDLFKRE
AIVRAILRSIEALPPNPAVNSDAAR
>pB8_007 parE-like, plasmid stabilization protein ParE
MRVVWTPEAQQDRADVWDYIAADNPRAAARMDEIFSDAAARLIQHPMLGK
PGKIPGTRELIPHESYRLVYQIDGETVWILTLVHTARLWPPVRD
>pB8_034 qacEdelta1, small multidrug resistance protein
MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAFYFLSLV
LKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLL
ARSPSWKSLRRPTPW
>pB8_009 qacF, small multidrug resistance protein (SMR)
MSPYIPLSIAIVAEVIATTAMKSSDNFTRLVPSVIVVVGYVVAFYFLSIT
FKFIPTGIAYAIWAGAGIVLITLMGWIVHKQTLDLAAMLGMGLIVSGVLV
INIFSKSGAH
>pB8_012 ssb, single strand DNA binding protein
MSHNLFQFIGNLTRDTDVRHSENSARAVFDLAVNRVWRNAAGAKQEQTDF
FRIKSFGGLAENAGKYLGKGSKVFVQGRIEPTKYEKDGKTEYGFDFIAEE
IEYLDTKAPGGGQ
>pB8_035 sul1, dihydropteroate synthase
MVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDVGPAASH
PDARPVSPADEIRRIAPLLDALSDQMHRVSIDSFQPETQRYALKRGVGYL
NDIQGFPDPALYPDIAEADCRLVVMHSAQRDGIATRTGHLRPEDALDEIV
RFFEARVSALRRSGVAADRLILDPGMGFFLSPAPETSLHVLSNLQKLKSA
LGLPLLVSVSRKSFLGATVGLPVKDLGPASLAAELHAIGNGADYVRTHAP
GDLRSAITFSETLAKFRSRDARDRGLDHA
>pB8_038 tniA, possible transposase
MATDTPRIPEQGVATLPDEAWERARRRAEIISPLAQSETVGHEAADMAAQ
ALGLSRRQVYVLIRRARQGSGLVTDLVPGQSGGGKGKGRLPEPVERVIHE
LLQKRFLTKQKRSLAAFHREVTQVCKAQKLRVPARNTVALRIASLDPRKV
IRRREGQDAARDLQGVGGEPPAVTAPLEQVQIDHTVIDLIVVDDRDRQPI
GRPYLTLAIDVFTRCVLGMVVTLEAPSAVSVGLCLVHVACDKRPWLEGLN
VEMDWQMSGKPLLLYLDNAAEFKSEALRRGCEQHGIRLDYRPLGQPHYGG
IVERIIGTAMQMIHDELPGTTFSNPDQRGDYDSENKAALTLRELERWLTL
AVGTYHGSVHNGLLQPPAARWAEAVARVGVPAVVTRATSFLVDFLPILRR
TLTRTGFVIDHIHYYADALKPWIARRERWPSFLIRRDPRDISRIWVLEPE
GQHYLEIPYRTLSHPAVTLWEQRQALAKLRQQGREQVDESALFRMIGQMR
EIVTSAQKATRKARRDADRRQHLKTSARPDKPVPPDTDIADPQADNLPPA
KPFDQIEEW
>pB8_037 tniB, NTP-binding protein
MDEYPIIDLSHLLPAAQGLARLPADERIQRLRADRWIGYPRAVEALNRLE
ALYAWPNKQRMPNLLLVGPTNNGKSMIVEKFRRTHPASSDADQEHIPVLV
VQMPSEPSVIRFYVALLAAMGAPLRPRPRLPEMEQLALALLRKVGVRMLV
IDELHNVLAGNSVNRREFLNLLRFLGNELRIPLVGVGTRDAYLAIRSDDQ
LENRFEPMMLPVWEANDDCCSLLASFAASLPLRRPSPIATLDMARYLLTR
SEGTIGELAHLLMAAAIVAVESGEEAINHRTLSMACRQPLAQPRHRGRTA
SDLEATGPSHPDMDLDARTDVRFRVLGVLR
>pB8_004 tnpA, Transposase
MTTKSERLTVLSDAEQEALYGLPDFDDAQRLEYLALTETELALASSRPGL
HAQVYCILQIGYFKAKHAFFRFDWSEVEHDCAFVLSRYFHGESFEHKPIS
KHEHYTQREWIADLFGYRPWAAEFLAQLAQQAAQTVRRDVMPGFIAAELI
VWLNEHKIIRPGYTTLQELVSEALSAERRRLAGLLSEVLDESAKAALGRL
LVRDDTLSQLAALKQDAKDFGWRQMAREREKRATLEPLHRIAKALLPKLG
VSQQNLLYYASLANFYTVHDLRNLKADQTYLYLLCYAWVRYRQLSDNLVD
AMAYHMKQLEDESSAGAKQSFVAEQVRRQQDTPQVGRLLSLYIDDSVPDP
TPFGDVRQRAYKIMPRDTLQTTAQRMSVKPVSKLALHWQAVDGLAERIRR
HLRPLYVALDLAGTDPGSPWLVALAWAKDVFAKQQRLSQRPLAECPAATL
PKRLRPYLLTFDADGKPTGLHADRYEFWLYRQVRKRFQSGELYLDDSLQH
RHFSDELVSLDEKAAVLAQIDIPFLRQPLDAQLDALATELRAQWLAFNRE
LKQGKLTHLEYDKDTQKLTWRKPKGENQKAREKAFYEQLPFCDVADVFRF
VNGQCQFLSALTPLQPRYAKKVADADSLMAVIIAQAMNHGNQVMARTSDI
PYHVLESAYQQYLRHATLHAANDCISNAIAALPIFPYYSFDLDALYGAVD
GQKFGVERPTVKARHSRKYFGRGKGVVAYTLLCNHVPLNGYLIGAHDYEA
HHVFDIWYRNTSDIVPTAITGDMHSVNKANFAILHWFGLRFEPRFTDLGD
QLKELYSADDPALYDQCLIRPAGRIDRDLIVSEKPNLDQIVATLGLKEMT
QGTLIRKLCTYTAPNPTRRAVFEFDKLIRSIYTLRYLRDPQLERNVHRSQ
NRIESYHQLRSTIAQVGGKKELTGRTDIEIEISNQCARLIANAVIFYNSA
ILSRLLMKYEASGNAKAHALLTQISPAAWRHILLNGHYTFQSDGKMIDLD
ALVAGLELG
>pB8_005 tnpR, resolvase
MLVGYMRVSSDSDRQSTNLQRDALLAAGVDARHLFEDHASGAKDDRAGLA
RALEFVRPGDVLVVWKLDRLGRSLSHLLAIVTSLKEKQVAFRSLTENLDT
TTPSGEFLFQVFGALAQYERALIQERVVAGLAAARKRGRIGGRPQAITGE
KLEAIVAALDGGMSKAAVCRNFGVKRTTLIETLARVGWTGSRGASSR
>pB8_039 traC2, TraC2 primase
MPITKAEAQGVTRAFVRDYPGALELAYKFREDAAELYGPRAAEVPADMKG
GYVPKETLHAGRAYRGRVDVPLQNVESASDLLMTLRHEVLGHYGANTFAP
GEKRALLDGLAAARNEPTLKPLWDDVNRRYAGQSLDVRAEEVFALHCEGI
EPSQHQVADQVQQRGQQSFTETCIARVRPMQADDLHNIVCMVAQGLRDRS
RTQQNFPQFNELFRRDENMEPKKPFHEVVAEKLIEQLKAGTAPWQKPWEP
GEPNAYLPMNPTTGKRYKGINAIHLMAQGRSDARWMTYKQAAAVGAQVRK
GEKGTPVQYWKFSEEQDKLDDSGRPVLDAKGQPVKETVMLERPRVFFATV
FNGEQIDGLPPLQPKKEQTWNAVERAEHILKASGATITHAAGDRAFYRPS
TDSITLPERGQFPSSDRYYATALHELGHWTGHASRLDRDLAHPFGSEGYA
KEELRAEIASMIVGDELGIGHDPGQHAAYVGSWIKALQDEPLEVFRAAAD
AEKIHDYVLAFEQKQVQEQDQQQSQAQDEAVAQALAVDIAEVLDNPDVSF
SHYQAFQGDTLEDALRSRGLETVGSITGTDPEQFYAVAHDRLSPVFGIDP
SHTDTDNAYLERKGLAQEFANMAEQLHLAQQLQQHGEQIVSSIDAEARWS
DGQRIFAFHDQDGEPHQVRSLDELNNYAPDQLMALPALTQQQAAVADQEA
NMTPPTIDQAAALLAAHPADAVQGIEQAAAARRQLAAGEIDGQAFADATR
QHLGVELPPDWSGELRIVGVAEQDGQTVDAAQAGIEPQAFQVYARKADAQ
FGEDAFAFVAGTRTEGQAEALAERLHLVDALGTDNQHERAAKLARVQEER
VRRDPNATEEDISAAKEARKTAEASAMLNDSDAQRRAAELERQERDRQQA
QPQAEKPERQYINVPYKEKDEAKSLGARWDRQQQSWYVPPGTDAAPFAKW
AQGAATAAVEPRSAQPAPEAQGEAQKPAQQAQQARQYLAVPYEQRNAAKA
AGALWDKAAKSWYVGPRADAAKLERWKPENVQAQQGPAMTPREEFAEAMR
SAGLFTGSNAQGDHPIMDGKRHRVPVEGGKKGALDGFYVGHLDGHPAGRI
INNKTGTDITWKSKGYALSDQEKAKLQAEAAEKLAQRAVEQDKAQEATAQ
RVGRQMADLVPIEQPTPYLQAKGIQAQAGVMTDREGQKTYIPAFDAEGKQ
WTMQYIQEDGTKRFAKDSKKEGCFHPVGGMDALAAAPALVISEGYATAAQ
VAEAVGHATVAAFDSGNLEAVAKALHAKFPDKPVIIAGDDDRHLVMTHGN
NPGREKAEAAAQAVGGKAIFPIFAPAENTYPRDLPAITPDSFKTHLRAEQ
RLADAAAGKVELAGDEAAKLKASMLSGAQIAALSTMKQHTDFNDLAHKSE
LGIEGVKRQIGAAISQVQRDEQQHQEQKHVEKKQQQIEQRPRRAARIG
>pB8_040 traD, TraD protein
MNEQTTTNTAAHDEPLAVLPPVDDDAAGREAVREKMADALTPGFQVEFDP
DEAERVGAFVEDALSEQDAAASGDDLVEVDGALEPAFLDDEGPSADIPPF
ITTTNARELYDLRPGETVAQAAARKASEG
>pB8_041 traE, possible DNA topoisomerase
MRLFIAEKPSVAKAIAGELGATGKGDGFIECGTDKVTWCFGHMLEQADPD
EYTPDDVPRGQSGKKVWRVDELPIIPESWILKPKDDAKKQLAVIGKLLKE
AKEIVNAGDPDREGQLLVDEVLEHFRNSKPVRRFWVSAQDSVSVKRGLAA
LKENTTYAGWADAARGRQRADWLIGMNLSRAYTLRAQRGGSRALLTVGRV
QTPTLALVVARDREIEAFKAVPYHTIRAVVQHAGGSFAAAWKAKEDQAGL
DSEGRLVDTAVADALVAAVKGQPGTIAAYKQEAKKQNQPLAFALSDITAL
ASAKFGYSAEDVLNTCQALYETHKLTSYPRTDCAYLPESQHADAPRVLEA
IKHVNPELAGLVDGADPRIKSKTWDDSKITAHHGIVPTMQKGSKAALSER
ERNIYDLIVRAYLAQFYPLHEYMQTTVGVEIAGENFAASGKVVTRNGWRD
VYSQADEEGEKDEDDDSGTQALPSMAQGDAVTCTDATRKDAKTKPPARFT
EGTLIRAMENIHKFVSDAEHKKMLREGDGIGTSATRASIISELKRREFLA
VKGKQIISTTLGRSVIDALPEVVKSPVLTALYERMLKGVEQGTAALDAFI
TKQETFIRDQVAKANSGAVTIAGGKEAAPVSSLHKCMACGSGLSRRPSKK
KGQFWWGCSNFPTCKQTYPDLKGRPDYSKGRNGQASE
>pB8_042 traF, possible protease
MSRILKRIAAGVVIAGVAALLLAAGGYAAGARVNTTKSIPVGLYWTSSAP
VEKGAYVLFCPPQLGVFDDAKERGYIGAGFCQGGYGYMMKRVLAAKDDAV
AVADDGVRVNGELLPLSAPIKADKAGRPLPRYQSNSYTLGNSEVLLMSDV
SATSFDGRYFGPINRSQIKTVIRPVITW
>pB8_043 traG, TraG protein
MKIKMNNAVGPQVRTAKPKPSKLLPVLGAASMVGGLQAATQFFAHTFAYH
ATLGPNVGHVYAPWSILHWTYKWYSQYPDEIMKAGSMGMLVSTVGLLGVA
VAKVVTSNSSKANEYLHGSARWAEKKDIQAAGLLPRERNVLEIVTGKAAP
TATGVYVGGWQDKDGNFFYLRHSGPEHVLTYAPTRSGKGVGLVVPTLLSW
GASSVITDLKGELWALTAGWRQKHAKNKVLRFEPASTSGGVCWNPLDEIR
LGTEYEVGDVQNLATLIVDPDGKGLDSHWQKTAFALLVGVILHALYKAKD
DGGTATLPSVDAMLADPNRDIGELWMEMATYGHVDGQNHHAIGSAARDMM
DRPEEEAGSVLSTAKSYLALYRDPVVARNVSRSDFRIKQLMHEDDPVSLY
IVTQPNDKARLRPLVRVMVNMIVRLLADKMDFEGGRPVAHYKHRLLMMLD
EFPSLGKLEIMQESLAFVAGYGIKCYLICQDINQLKSRETGYGHDESITS
NCHVQNAYPPNRVETAEHLSRLTGQTTVVKEQITTSGRRTAAMLGQVSRT
YQEVQRPLLTPDECLRMPGPKKNAQGEIEEAGDMVIYVAGYPAIYGKQPL
YFKDPVFSARAAIPAPKVSDRLRAVAQAETEGEGITI
>pB8_044 traH, TraH protein
MSEPKDQSIEDELDAALAALDSGPLPTSTLPEPQPSPEQATAGQPPAEAT
APTPAFTPPPSTGSPTLDALEENRRPKASTVCEHCPNSVWFASPAEVKCY
CRVMFLVTWSSKEPNQITHCDGEFLGQEQE
>pB8_044 traI, DNA relaxase
MIAKHVPMRSLGKSDFAGLANYITDAQSKDHRLGHVQATNCEAGSIQDAI
TEVLATQHTNTRAKGDKTYHLIVSFRAGEQPSADTLRAIEERICVGLGYG
EHQRISAVHNDTDNLHIHIAINKIHPTRHTMHEPYYPHRALAELCTALER
DYGLERDNHEPRKRGAEGRAADMERHAGVESLVGWIKRECLDEIKGAQSW
QELHQVMRDNGMELRVRANGLVFEAGDGTMVKASTVARDLSKPSLEARLG
PFEASPERQAQTTAKRQYRKDPIRLRVNTVELYAKYKAEQQSLTTARAQA
LERARHRKDRLIEAAKRSNRLRRATIKVVGEGRANKKLLYAQASKALRSE
IQAINKQFQQERTALYAEHSRRTWADWLKKEAQHGGADALAALRAREAAQ
GLKGNTIRGEGQAKPGHAPAVDNITKKGTIIFRAGMSAVRDDGDRLQVSR
EATREGLQEALRLAMQRYGNRITVNGTVEFKAQMIRAAVDSQLPITFTDP
ALESRRQALLNKENTHERTERPEHRGRTGRGAGGPGQRPAADQHATGAAA
VARAGDGRPAAGRGDRADAGLHAATVHRKPDVGRLGRKPPPQSQHRLRAL
SELGVVRIAGGSEVLLPRDVPRHVEQQGTQPDHALRRGISRPGTGVGQTP
PGVAAADKYIAEREAKRLKGFDIPKHSRYTAGDGALTFQGTRTIEGQALA
LLKRGDEVMVMPIDQATARRLTRIAVGDAVSITAKGSIKTSKGRSR
>pB8_045 traJ, oriT binding protein
MENDEKEHGRRRRQHLRVPVFPEEKDEIEANAKRAGVSVARYLRDVGQGY
QIKGVMDYQHVRELVRVNGDLGRLGGLLKLWLTDDVRTLQFGEATILALL
GRIEATQDEMSRIMKAVVQPRAEP
>pB8_046 traK, oriT binding protein
MPKTYPEELAEWVKGREAKKPRQDKHVVAFLAVKSDVQAALDAGYAMKTI
WEHMKETGRLRCRYETFTQHVKRYIKAAPVASPPPPATPPDSQPKGAKPE
PKAAPPASESKSEPPKIGGFTFDATPKKEDLL
>pB8_047 traL, TraL protein
MAKIHMVLQGKGGVGKSMIAATIAQYKAGKGQKPLCIDTDPVNATFEGYK
ALNVRRLNIMDGDEINTRNFDALVEMIASAEGDVIIDNGASSFVPLSHYL
ISNQVPALLQDMGHELVVHTVVTGGQALVDTVSGFAQLASQFPAECLFVV
WLNPYWGPIEHEGKGFEQLKAYTANKGRVSAIIQIPALKEETYGRDFAEM
LQDRRTFDEALADSALTIMTRQRLKIVKTQLFAQLENAAVL
>pB8_048 traM, TraM protein
MAADDKIEELIREIAAKHGIAVGRDDPILILQTINMKLMQDSASAQQEIL
DAFKSELESIAHRWGDDAKGKAERTLNAALAASKDAMTRGMQEGAKAAAE
AVRREVEAVTAQLVAPIREARRVAMMNMVAAGMAVVAAGLALWASL
>pB8_013 trbA, DNA binding protein
MYNYIFFTNVLRLLDERHMTKKELSDRSGVSISFLSDLTTGKANPSLKVM
EDIAQALETPLPLLLESTDLDKEALDALAGGKAPRSLPPGFERVAAVLPE
HQAFIVKKWGEATRKKLRGS
>pB8_014 trbB, ATPase
MTDQKPEHNSIKERAKKKLERDMGPELLAALNDPKTVEIMLNADGKLWLE
RLGEPMKCIGTLRVAQAQAIIETIAGYHGKEVTRSKPILEGELPLDGSRF
AGQLPPVVPAPTFAIRKKAVAIFTLDQYVERGIMTAPQREALIAAVRAHR
NILVIGGTGSGKTTLVNAIINEMVIQDPTERVFIIEDTGEIQCAAENYVQ
YHTSIDVNMTALLKTTLRMRPDRILVGEVRGPEALDLLMAWNTGHEGGAA
TLHANNAKAGLDRLAMLISMHPDSPKPIEPLIGEAVHVVVHIARVEGSRR
IQEILEVSGFANGQYITKTL
>pB8_015 trbC, putative prepilin
MQATFPAFRLNRNALFYMGLFALLAFFLLAPQHAFASEGTGGSLPYESWL
TNLRNSVTGPVAFALSIIGIVVAGGILIFGGELNGFFRTLIFIVLVMALL
VGAQNMMSTFFGRGAEIAALTDGALHQVKVAALDVAGFPGEAVMRWAERG
HIAG
>pB8_016 trbD, TrbD protein
MALRAIPIRRAGNRENLFMGGDRELVMFSGLLAGALIFSAQEVRATVFGI
ALWFGALFALRLMAKADPKLRHVYLRHRRYKPYYPARSTPFRDNTPSQGK
QYK
>pB8_017 trbE, TrbE protein
MIEAIAIAIAVLGAVLLLILFARIRAVDAELKLKKHRAKDAGLADLLNYA
AAVDDGVIVGKNGSFMAAWLYKGDDNASSTEEQREMVSFRINQALAGLGN
GWMVHVDAVRRPAPNYSERGVSSFPDSVSFAIDEERRRLFEGLGAMFEGY
FVLTVTWFPPVLAQRKFVELMFDDDAVAPDHTARTTGLIAQFKREITSLE
SRLSSAVKMTRLRGQKVVSEEGREVTHDDFLSWLQFCVTGLHHPVMLPSN
PMYLDAVIGGQELWGGVVPKIGRKFIQVVAIEGFPLESTPGVLSALAELP
SEYRWSSRFIFMDQHESLKHLDKFRKKWKQKIRGFFDQVFNTNTGSINQD
AAAMVGDAEAAIAEVNSGLVAAGYYTSVVVLMDEDRERLAASALLVEKAV
NRLAFAARIETINTLDAYLGSLPGHGVENVRRPLINTMNLADLLPTSSIW
TGSATAPCPMYPPLSPALMHCVTVGATPFRLNLHVRDLGHTFMFGPTGAG
KSTHLGIIAAQLRRYAGMSIYAFDKGMSMYPLAAGIRAATKGKSGLHFTV
AADDDRLAFCPLQFLETKGDRAWAMEWIDTILALNGVNTTPAQRNEIGNA
IMSMHASGARTLSEFSVTIQDEAIREAIKQYTVDGSMGHLLDAEEDGLSL
SDFTVFEIEELMNLGEKFALPVLLYLFRRIERALKGQPSVIILDEAWLML
GHPAFRAKIREWLKVLRKANCLVLMATQSLSDAANSGILDVIVESTATKI
FLPNVYARDEDTSALYRRMGLNARQIEILATAIPKRQYYYVSENGRRLYD
LALGPMALAFVGASDKESVATIKSLEAKFGHEWVHEWLAGRGLNLNDYLE
AA
>pB8_018 trbF, TrbF protein
MSIADTLKGLIFKKPANSAEPRDPRRSKEPLAGGRRAGEAENPYLAARRT
WNDHVGGVVSQRQTWQVIGILSLLIALAGVGGVIHIGSQSKFIPYVVEVD
KLGQTVAAGPVQAAGKADPRVIHAAVADWMSCARMVSPDVALQRKCVFKA
YSMLAPNDPATPKMNEWLNGTPDSSPFKRAEKEMVSVEIKTVIPQTPDTW
QVEWVETTRDRQGTLKGQPVTWRALVTTYIAEVTPNTTDEQLRNNPLSIY
VRDYSWSRIQ
>pB8_019 trbG, TrbG protein
MNSRSSTMKKTLSALIVGAAVAVPSLALAAPGDDIADKYFNKTNPTLTAQ
ERAALAIAKRWEAGSATGIKPVAGSGGAIKFVYGAQQPSIVCAVLQVCDV
ALQPGEQVNSINLGDTARWTVEPAITGSGATEVQHLIIKPMDVGLETSLV
VTTNRRSYHFRLRSHRTEYMPQVSFTYPEEAQAKWDAIQRREKQERTDNT
LPATGEYLGDLSFDYELSGSASWKPVRVYNDGRKTIIEMPGTMQQTEAPT
LLVVRKEGGLFTDDETVLVNYRVQGNRYIVDTVFDRAILIAGVGSSQDRV
TISRRK
>pB8_020 trbH, TrbH protein
MRKIVSLALLALALGLGGCATTSQYGNFVQSAALDQQKLATDAVQQLATL
YAPARTRLELQQPTPDPFGQALVKSLRDKGYALLEYAPAGASTQAPASAA
SQASAPATTAASGGLPLRYVLDQAGDSNLYRLTLMVGNQSITRPYLAQNG
TFAPAGYWVRKE
>pB8_021 trbI, TrbI protein
MTENADQMAPDASPGEVSKKAGVRRVNNMPMYILGGVLLSFVLVMALVAA
DRAAKQNAPADGPKEKAGNTSMFAKEIAGDKTGGLIEPASPLKVPDMPTG
PASAPLEIARPSNPDAPPAPPANPGNPGQPVNDDEAQRIRMAKMQMFGEA
VKAKTTVRVDAPRSNGSAPGGPSTYTGTPQTRDEMLNRIAAVQQQIDAQR
SNDPTAAYQARLAQIRGMGVGGGGAAPAAGGMGAGGAPQLLQTSTSGGGR
NSMAQFGQGGQGDRWKLDSQPEAPRTPFELRAGFVVPATLISGINSDLPG
QIMAQVAQDVYDTPTGKHLLIPQGSRLVGSYSSDVAYGQARVLVAWQRIV
FPDGKAMDIGAMPGADSAGYAGFHDQVNNHYVRLFGSAFLMSGVTAGITY
SQRQNQATNTYGAPSASSALSEALGQQLGQVTAQLIAKNLSISPTLEIRP
GYRFNVVVTKDMTFSKPYRSFDY
>pB8_022 trbJ, TrbJ protein
MKPKFLAAKLALVIAVSSTLAVTPVQAGIPVIDGTNLSQNIMTAIESVAQ
TLKQIEQYSTQLQQYQNQLQNTMAPAAYIWDQAQSTINGLMNAVNTLDYY
KTQLGSLDSYIGKFQDVNYYKNSPCFTAAGCSDAERAALRNVAQLASESQ
KKANDALFKGLDRQQTNLTADAATLQRLQSAAQGAQGQMQAIGYANQLAS
QQANQLLQIRGLLIAQQNAMATKMQADADKEAQQAAAAAQLRQGSYRASP
ARTW
>pB8_023 trbK, TrbK protein
MKAIKALSLASAALVAALVAGCDNKPATAPMPEVNDENCKPENIAKIEDK
GVQQAFSSLCLRRGGDFKPSPKREW
>pB8_024 trbL, TrbL protein
MRMPANLKTLALPLFVWLAFFAVDAHAAIDNAGVFDSVLDRYQAAASGWA
GVITTAATWLFWTLVVISMVWTFGMMALRKADIGEFFAEFVRFTIFTGFF
WWALTNGPNFASSIYASLRQLAGNATGLGNALSPSGIVDVGFAIFDKVMD
QSSVWSPVDSMAGILMAVAILVILALVGVNMLLLLASGWVLAYGGVFFLG
FGGSRWTSDMAINYYKVVLGVAAQLFAMVLLVGIGKTFLDDYYSRMSAGI
SLKEMGVMLIVVIILLALVNKIPPLIAGIITGASVGGAGIGQFGAGAALG
AAGMAAAAAATGGAALAAGAASAAGGASAVMAAFSKANENVSAGTDVMSA
FSGGGSSGGGAGGGGDAGTGSTPFAQAAGFSGSSGGGSSSGGGSPSTGSS
SGSSKGGDKGGGKADAGGQGSSSTASTGSSADKAAKNEPKPAGGAGQGQQ
AAPGSTGPGLLASAASALGTAGRIAADAGANLAKGTADVAKAKAASLREA
AAERIADTTGGKIAAAIKAQGSGTAENIDVPDQQPAPSFGDNSLAGGPAD
ADPESEVAAFANREQGRDGTTA
>pB8_025 trbM, TrbM protein
MKKKLFALAALVAALGSTAGTASAQDVLTGDTRLACEAILCLSSGTRPSE
CTPSLSRYFNITKRKLSDTIRARLNFLQLCPVASQTPEMQSLVSAISRGA
GRCDAQSLNSTLVMWTGGYDDGRTYISNQLPDYCGAYTGHAYTDFASSGT
LPRYVGTPERGGYWVEARDYDRALAEYNERIRREDEERRRQSWLN
>pB8_026 trbN, putative muramidase
MPFFADLPPQLQERVVCSISAAVKYEVPVNIVLAVAEKEGGKPGQWVRNS
NGTHDVGPMQFNTAYLGDLARYGITANDVAAAGCYSFDLAAWRLRMHIRN
DKGDLWTKAANYHSRTPQYNAVYRADLMRKASKWADWLEARFVTLDVTKA
GATPSTPSQPATVAQRATPAARPAPAPQQAAPAAAAARSVSVAGYVPRTV
SFNTSREGSAE
>pB8_027 trbO, TrbO protein
MDKFHAFMMRYTLGVGRLLQAYCKWAEGQAKNQLDLLLLGLGPIFALGLL
LWALPAWIGKPIAFVLSLPALYIIFLVLRAYAIRGGRR
>pB8_028 trbP, TrbP protein
MKALRIPDGTVEALKWLALVLMTGDHVNKYLFNATLPVLFEAGRVALPLF
VFVLAYNLARPGTLERGVYGRTMSRLAMFGALASVPFVALGGLYAGWWPL
NVMFTLLVVTATAYLVERGGKLHLAAAGVVFLVGGSSVEYWWPAVAFGLA
VWSYTRRPSWAAAAVAVLACAALWFVNRNLWALAALPVLFLASRVDVRVP
RLRWAFYAYYPLHLASLWLIRIPMSKAGYLFF
>pB8_011 trfA, replication initiation protein
MQNEFNEQEYRRKLIEGGLSEADATDLAARTAAARRDSGSAGGAFRPAGS
LFELPATAGDNEAALPPKLPTPASAAVERSERMAQESAELARTMGLPPEP
RTAVNKMAEQIGALAQDKRSSAMATKKRTAGGELAEKVSEAKQTALLKHT
KQQIKDMQLSLFDLAPWPDHMRALPNDFGRSAIFTVRNKKVPRAALQGQS
IYHVNKDVEITYTGIELRADDDELVFAQVLEYAKRTALGEPVSFTFYELC
QDLDWSINGRYYTRAEECLTRLQASAMQFSSQRIGRLESVSLIRRFRVLD
RGKRTSRCQVEIDAEIVVLFAGDHYTKFVWEKYRKLSPTARRMFDYFATH
KEPYPLKLETFRLMCGSDSTRPKKWREQVGEACDELRENGLVESAWVNDD
LVHCKR
>pB8_029 upf30.5, putative outer membrane protein
MRKPVLLALSLAFLVSAQSALAAGDAGNFGTPIKSGVSVSFPDSSATFQP
TPEALELLADARNAAIIYISGRTSTLRPSAADEALALRRALSARSYLVAR
GVSPLKIMVNFASAADFVADNSTAEGRRENQRVDIEVVYIPTY
>pB8_030 upf31.0, putative adenine methylase
MRYPGGKGGAGVYQTIINNIPPHDTYIETHLGGGNILERKRPAARSVGID
VDPEVIEVWQQLDVPGLELHHGDAVAWLESHQFTGSEFVYADPPYVMDSR
RGGKLYRHEYDDADHVRLLDVLAGLPCAVMVSGYSSTIYDSSPLASWRTI
DFNAMTRGGIAIERLWMNYPEPAELHDLRYLGSNFRERERIKRKKARWQA
KLAKLDPLERAAIMECLRELEAAE