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# Streptococcus pyogenes M1 GAS, SF370

>SPy0838 conserved hypothetical protein
MENWKFALSSIWGHKMRSILTMLGIIIGVAAVVIIMGLGNAMKNSVTSTF
SSKQKDIQLYFQEKGEEEDLYAGLHTHENNHEVKPEWLEQIVKDIDGIDS
YYFTNSATSTISYEKKKVDNASIIGVSKDYFNIKNYDIVAGRTLTDNDYS
NFSRIILLDTVLADDLFGKGNYKSALNKVVSLSDKDYLVIGVYKTDQTPV
SFDGLSGGAVMANTQVASEFGTKEIGSIYIHVNDIQNSMNLGNQAADMLT
NISHIKDGQYAVPDNSKIVEEINSQFSIMTTVIGSIAAISLLVGGIGVMN
IMLVSVTERTREIGLRKALGATRLKILSQFLIESVVLTVLGGLIGLLLAQ
LSVGALGNAMTLKGACISLDVALIAVLFSASIGVFFGMLPANKASKLDPI
EALRYE
>SPy1468 conserved hypothetical protein-phage associated
MSQLRADKKGTHRVAFDRNKKKLLKAATVCGICGKPVDKSLKYPHPLSAA
IDHIVPIAKGGHPSALENLQLTHWQCNRQKSDKLFANQASNEPKTIGNRN
LPQSRDWSSFAFKK
>SPy1850 putative esterase
MVYEMTLAVIKCIENHLHKKVYKGASLALFQSGRWQEYHIGTIDGRRPVD
ANLVYDLASVSKVVGVATICNILLNNGTLALDDPLKVYYPSIADATVTIR
QLLTHTSGLDPYIPNRDVLNAQQLRKALNHLTQKENKNFYYTDVNFLLLG
FMLEELFSESLDQIFDKTIFTPFGMYHTSFGPRPEAVPTLKGVSDGEVHD
PKAKILKKHSGSAGLFSTLADLESFSNHYLNDPFSDCLWRNYSQQTIERS
LGWNLDGDWISHTGYTGPFLMLNKKEQTAAIFLTNRTYDEDDKSKWLKER
QLLYNALKHDLTTPVS
>SPy0045 conserved hypothetical protein
MIYNNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGVSIANN
IISIYQSLFIALGAAVSSLIARSIGENNQNKQLNYMAGVLQVTLLLSVGL
GLLSVAGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVR
AQGYPKIPMQVSLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGVF
LLCQFIPIKQVAKRLMRPLDKIIFDLSLPAAGERLMMRAGDVLIIGIVVR
FGTTALAGNAIGETLTQFNYMPGLAMATATIILVARQLGGGKVTEIRYII
REAFILSTLMMLVMGALTYLLGPSLLPLFTQNTDAQRSAMIVLLFSLLGA
PATAGTLVYTAVWQGLGKAKLPFYATTIGMWVIRIGLGYVIGVVWQYGLI
GVWMATVLDNTSRWFILSKHFKKYQEITFH
>SPy1674 putative ABC transporter (ATP-binding protein)
MIEFKHVSKLYGDKEALSDLNVTINDGEIFGLIGHNGAGKTTTISILTSI
IEASYGEVFVDGQLLTENREAIKKQIAYVPDSPDIFLNLTPNEYWQFLAK
IYGVSDEDREERLAQLTTLFELKEEVNQTIDSFSHGMRQKVIVIGALVSN
PNIWILDEPLTGLDPQASFDLKEMMKAHAASGHTVLFSTHVLSVAEQLCD
RIGILKKGKLIFVGTIDELKEHHPDKDLESIYLELAGRKAQEEG
>SPy1470 conserved hypothetical protein-phage associated
MIKIDEIHRILGIDEVYKAPKRLTDILFDKDSREDIFRQFLKYETDVSYD
WFMQYFEEEQADRKNKKQDFTPKSVSTLLSKIISGNQYYEVAVGTGGILI
QAWQEQRLNDSPFTYRPSKYWYHVEELSDKAVPFLLFNMSIRGINGVVVH
GDSLTRQVKNIYFLQNTKDDMLSFSDINVMPRTQDIEREFNVKEWIGDGI
EHIENPLIEWI
>SPy0744 putative ABC transporter (ATP-binding protein)
MSFVQLTNVVKSYKNGKKAVNDVSLSIEAGNIYGLLGPNGAGKSTLINLI
LGLIPLSSGKITVLGQSQKTIRKISSQIGYVPQDIAVYPDLTAYENVELF
GSLYGLKGAQLKKQVLKSLEFVGLHSQAKQFPSQFSGGMKRRLNIACALV
HSPKLIIFDEPTVGIDPQSRNHILESIRLLNKEGATVIYTTHYMEEVEAL
CDYIFIMDHGQVIEEGPKFELEKRYVANLANQIIVTLTDSRHLELADKPD
WSLIEDGEKLMLKIDNSDMTSVVHQLTQANITFSEIRHNHLNLEEIFLHL
TGKKLRD
>SPy1149 putative ABC transporter (ATP-binding protein)
MIKTDHHLLKRVLQDLLKKPLPVCILVIASFVQVGLSVYLPVLIGKAVDM
SLSVNSWQTLKWLLGQMLVIIVVNTLIQWVMPLVYSRLLYQYSQQLKDKL
LEKIHRLPFAYLDRQTIGDLVSRVITDTEQLINGLQMVFNQFILGLLTIL
CTIIAMAQIDWLMLILVLVLTPSSLFLARFIAQKSFHYAQAQTKSRGNLA
QFTEEILRQEGLVQLFNAQEQSICDYHVLNKTYCEASQKAIFYASTVNPA
TRFINSVIYALLAGLGAVRIMAGLFSVGQLTTFLNVVVQYTKPFNDISSV
LAEIQSSLACAQRLYDLLDIEIKEQEHFLTFKASAVKGQIDFEEVSFSYQ
KDRPLLKDINFSVPAGSKVAIVGPTGAGKSTLINLLMRFYELDAGSIKLD
KVPIKCYAKEELRSITGIVLQETWLKDATVHELIAYGSEEASRDEVVAAA
KAAHAHFFIMQLPKTYDTYLSASDDALSQGQLQLLAIARMFLKKPKVLVL
DEATSSIDIRTEAVIQEALKELMRGRTSFIIAHRLSTIQSADLILVMDQG
RLVEWGTHASLMSKNGCYVRLQKIE
>SPy1254 hypothetical protein
MENSIEAYLADSREKVTLGTVVDCFKGKAVSSKVVPGDVGLINLSDMGTL
GIQYHQLRTFQMDRRQLLRYLLEDGDVLIASKGTLKKVCVFHKQNRDVVA
SSNITVLRPQKLLRGYYIKFFLDSPIGQALLDVADHGKDVINLSTKELLD
IPIPVIPLVKQDYLINHYLRGLTDYHRKLNRAEQEWEYIQNEIQKGLG
>SPy1255 hypothetical protein
MIKKTLWKDILRAIKNSKGRFISLFFLMALGSFALVGLKVTGPDMERTAS
RYLERHQVMDLTVLASHQFSQADKQELDTLKGAHLEYGHLLDVSLTSNQK
SLRLYSVPKKVSKPVLVKGSWPKRETDLVLSSSLAKNYQIGDELAVTSPM
EGLLTTTHFQVVGFANSSEVWSKSNLGSSSTGDGSLYAYAFVNPNVFKSA
FNLLRIRFSHLRLTNAFSKDYQKRVTQNQAHLDNLLKDNGQKRYDDLQNQ
YDLALKNGRAALAKETVKLAASEENLTFLEGSALQEAKHQIEQGKQALAK
EEKQLEQVQATKDKLEKPSYLTYNRSTLPGGEGYHTYATSTTSISNVGNI
FPVVLYLVAALVAFTTMTRYVDEERTSSGLLKAIGYSNKDISLKFLIYGL
LASFLGTTLGIIGGTYLLSTLISEILTGALTIGKTHLYSYWFYNGIAYLL
AMLSAVLPAYLIVKKELFLNAAQLLLPKPPSKGAKIWLEHLTFVWKALSF
THKVTIRNIFRYKQRMLMTIVGVAGSVALLFAGLGIQSSLAKVVEHQFGD
LTTYDILAVGSAKATATEQTDLASYLKQEPITGYQKVSYASLTLPVKGLP
DKQSISILSSSATSLSPYFNLLDSQEQKKVPIPTSGVLISEKLASYYKVK
PGDQLVLTDRKGQSYKVTIKQVIDMTVGHYLIMSDTYFKNHFKGLEAAPA
YLIKVKDKDSKHIKETASDLLTLKAIRAVSQNVNHIKSVQLVVTSLNQVM
TLLVFLSILLAIVILYNLTTINIAERIRELSTIKVLGFYDQEVTLYIYRE
TISLSLVGILLGIYLGKGLHTYIMTMISTGDIQFGVKVDAYVYLVPILVI
LSLLAVLGIWVNRHLKKVDMLEALKSID
>SPy0746 putative ABC transporter (ATP-binding protein)
MICFIKTLFVKIKRKKTSYVTFFLMPILTTLLALSLSFSNNNQAKIGILD
KDNSQISKQFIAQLKQNKKYDIFTKIKKEHIDHYLQDKSLEAVLTIDKGF
SDKVLQGKSQKLNIRSIANSEITEWVKAQTNYLLENYNIIGDVALGNEDT
FNRILQKNQQLNYDVKQVTLTDRSRSKAVSSTTTGFLLILMLGSTSVIYS
GILADKSSQLYHRLMLSNLSRFRYMLSYVCVGFVAFTIQIVIMLSLLKVF
NISFFVPTSLLLIIFFLFSLLAIGFGLLIGAITQNSQQSSQLANLIVMPT
SMLAGCLWPLSITPSYMQAIGKLLPQNWVLSAIAIFQSGGTLSQAWPYLL
ALMGTALALISFSSLLLKPTKL
>SPy1729 putative ABC transporter (ATP-binding protein)
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGF
LKPYQGSISIDGLTLAENAVAYRQKIGFIPETPSLYEELTLSEHINTVAM
AYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVID
PSLFILDEPFLGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCD
RFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKED
>SPy1257 putative ABC transporter (ATP-binding protein)
MAFIELKQVSKSYQIGETTVFANHEVSFEINKGELVVILGASGAGKSTVL
NILGGMDTVDAGQVIIDGKDIAHYTSKALTQYRRNAIGFVFQFYNLVPNL
TAKENVELAVEIVADALDPVTILKEVGLSHRLDHFPAQLSGGEQQRVSIA
RALAKNPKLLLCDEPTGALDYQTGKQILTLLQDMAQTKGTTVVIVTHNAA
IAPIADRVIFMHDAQVTKTVINKEPASIETIDY
>SPy1205 putative antimicrobial resistance factor
MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQNERIGIY
KEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYG
KTKKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTM
EIADSIQPRFQANIYTQENLEMQFPKHTRRLIKDAKQRGVKTYRVSQSEL
HKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQ
YRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTDQYPEE
VVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIW
ANMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHIANTMYKIR
KQLKNKH
>SPy2029 putative ABC transporter (ATP-binding protein)
MEDIIAALSSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTENTKRQL
IGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKG
VKNALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKD
FIDQKQVIYLEKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGL
TSGTEKIAYIPLHQWYNINGVVDATPEITIQTYRADDLKPVAKRVSDMLN
QTIPKSDYMFGVMNLKEFERQLDNLNKSNFVLLAGIASISLIVGGIGVMN
IMLVSVTERTREIGIKKALGARRKLILKQFLIEAVILTLLGGVIGVISGM
VSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIKASKLDPIE
ALRFE
>SPy0837 putative ABC transporter (ATP-binding protein)
MQLSNIVKSYQNGDQVLKVLKGINLTVYEGEFLAIMGPSGSGKSTLMNII
GLLDRPTSGDYTLHNTKIEILNDRELAKVRNDEIGFVFQQFFLLAKLTAL
QNVELPLIYAGVNVSKRREQAKQFLEKVGLGRRIKHLPSELSGGQKQRVA
IARALVNDPSIILADEPTGALDTKTGQQIMELLTELNKEGKTIIMVTHEP
EIADFATRKIIIRDGDITTDTTASVVID
>SPy0012 hypothetical protein
MRKLLAAMLMTFFLTPLPVISTEKKLIFSKNAVYQLKQDVVQSTQFYNQI
PSNPNLYQETCAYKDSDLTLPAGRLGVNQPLLIKSLVLNKESLPVFELAD
GTYVEANRQLIYDDIVLNQVDIDSYFWTQKKLRLYSAPYVLGTQTIPSSF
LFAQKVHATQMAQTNHGTYYLIDDKGWASQEDLVQFDNRMLKVQEMLLQK
YNNPNYSIFVKQLNTQTSAGINADKKMYAASISKLAPLYIVQKQLQKKKL
AENKTLTYTKDVNHFYGDYDPLGSGKISKIADNKDYRVEDLLKAVAQQSD
NVATNILGYYLCHQYDKAFRSEIKALSGIDWDMEQRLLTSRSAANMMEAI
YHQKGQIISYLSNTEFDQQRITKNITVPVAHKIGDAYDYKHDVAIVYGNT
PFILSIFTNKSTYEDITAIADDVYGILK
>SPy1790 putative ABC transporter (ATP-binding protein)
MAKPNRSTLSLVWRLLTLMKTLLPWIILAVGFAVMGFVITVSIPTGIAYL
GLLAIRQEVIPILALYLLIALAFLRGFVRYGEHYFGHFVAFHSLAAFRNL
IFKKLRALSPACLDSQDSGYLLKMIGEDIEALEVFFAHTIAPICTAILSA
GLMFWYFCQSSWQLALLALATYACLAIVIPIYFANILQVLLKSQNEGRKD
YLSYFLESLRSVKDLLQFQVLDEQFERLIKKSNHVNALDRNVAQAQFLQM
ALTFFWLGLMILAFSYMVFDGICHDSLSFDKGLLTFIAFTASFSPFLELG
RLPLGFKRAMNAARNIFDLLDENVIVDEGTKQIDRLRSVSFEDLSFAYPK
RQELVFKDLTVTFQEKGIIGIKGESGSGKSTLVKLIMKWYNWKTGDIFLN
DRNSCLLNAAKLQDTIAYVPQTAQLFQQSIRENLIFGRQDISDESIWNLA
EACGMKDRLLACKEGLDTIIKSPSDFSAGEGQRLELMRALLKDASCYIFD
EPTSNLDSLNEAILLDLIKTHCQGLVFLISHRPSTLACVDHLFCVKNGSL
KEVNKK
>SPy0676 conserved hypothetical protein, phage associated
MIKIDEIHRILGIDEVYKAPKRLTDILFDKDSREDIFRQFLKYETDVSYD
WFMQYFEEEQADRKNKKQDFTPKSVSTLLSKIISGNQYYEVAVGTGGILI
QAWQEQRLNDSPFTYRPSKYWYHVEELSDKAVPFLLFNMSIRGINGVVVH
GDSLTRQVKNIYFLQNTKDDMLSFSDINVMPRTQDIEREFNVKEWIGDGI
EHIENPLIEWI
>SPy1784 putative ABC transporter (ATP-binding protein)
MTQQSMLLSIEQVNKSYGKNQVLSDISFDIYKGEICGLVGQNGAGKTTLM
RILSGLIGKDSGQIKQLQPYRMGSIIESPTLYPNMTAHDNLYYAALQLRL
ADAKERIHEVLELIGLEKVSKKKKVKDYSLGMRQRLAIGLSILDFPEFLI
LDEPINGLDPAGIKEMRQIILNLRDCYGITILISSHILSELDLVVDRYVI
MHKGKVIKSMDKAELKAQVKVQIALHTSDDQLVKNRLLELGLRVETDGQM
LLIKPTLSVMELIKIVLDLPVEIFDIYHHQVSFEHYYLDLLGKDAASPLI
>SPy0773 putative ABC transporter (ATP-binding protein)
MSVLTFKQVTKTFQDGHHEINALKATDFSIEAGEFVAIIGPSGSGKSTFL
TIAGGLQTPSSGQLIIDGTDYTHLSEKERSRLRFKSVGFILQASNLIPFS
TVQQQLELVDHLTGSKEKAKANQLFDDLGITGLKHQLPQELSGGERQRAA
IARALYHDPALILADEPTASLDTEKAYEVVKLLAKESKEKNKAIIMVTHD
DRMLKYCDKVYRMQDGELCQER
>SPy0229 putative ABC transporter, ATP-binding protein
MLKDAILRYKWYALGSFFMVIGVVASSLLQPHYLKSVLSAVIQNNQEKIY
EVGKPLLIIALLGLMSGAINTVLAAKIAQGVSADMREKTFRKIQDFSYAN
IEAFNAGNLVVRLTNDINQIQSLVMMMFQILFRLPILFIGAFIMAVQTFP
QLWWVIVVMVILIALIMGLVMRQMGPRFGKFQRLMDKINRIAKENLRGVR
VVKSFVQEQQQYTKFKETSNDLLALNLSIGYGFSLMQPALMLVSYLAVYV
SINVVSTMVETDPTVIGNIASFMTYMMQIMFSIIVVGSMGMQVSRAFVSM
ARIRQILSTEPAMTFENEKEETISGSIVFDDVSFTYPNDDEPTLKHISFA
IEPGQMVGIVGATGSGKSTLAQLIPRLFDPQDGQILLGGKPIKTLSQTTL
RQSVSIVLQKAILFSGTIADNLRQGSAKADIDAMQKAAQIAQAKEFIDRM
DSRYESQVEERGSNLSGGQKQRLSIARGVINHPKILILDDSTSALDAKSE
KRVQEALSHKLEGTTTVIVAQKISSVVKADKILVLDQGQLIGEGTHAELV
ANNAIYREIYETQKGREE
>SPy1148 putative ABC transporter (ATP-binding protein)
MKRLRPYVKGYLKESILGPLFKLLEALFELLVPLLIANMIDISISQHNSQ
GILRVVLTLFGLATIGLLLSVTAQYFSSKAAVGFTRQMTDDLFKKIMFLS
KEDQDHLGYASLLSRLTSDSFQIQTGINQFLRLFLRAPIIVCGAMVMAYW
ISPSLTLWFVMMVIVLLTLVFVMSHLLGPLYLLIRRETDHLVRLTSQQLQ
GIRVIKAFNQTQKELQAFKQQNMLLSRHQYQAATLANVLNPMTFLVVNLT
LLILIWQGSWQVAHRSLSQGMLVALINYLLQILAELLKMTMLMGTINQSV
TAAKRINQVFVLADEAPLPLLKDGPISTHLLTIRHLTFTYPGAAEPSLYD
IQLSADQGEWIGIIGGTGAGKTTLIDLICQTYSQYSGEISLNWQGEVPKT
LTEWRNVIALVPQKAQLFKGTIRSNLLLGQSMPISDEELWRALELAQAKE
FVAALPEQLEAPVEAFGRHFSGGQRQRLAIARALLKPKPILILDDASSAL
DNETRGRLFKALKEELSDVLVILVTQSIKNLQFADKILVLEQGHQLDFAS
HDQLKVSNALYQEMLALYVKGEQK
>SPy0772 conserved hypothetical protein
MFLALNEMKQSKLRYGLIAGLLCLVAYLMFFLSGLAFGLMQENRSAVDLW
KADSVLLAKDADATLTLSQVSRAQENQITADKVAPLAQLNTVAWSVKNPK
DADKVKVSLFGIDSNSFIRPNIVKGRLFKTNKEVVLDQSLAKEEAFAIGK
DFYTSSSSQALTIVGYTQNARFSVAPVVYMNLEAFETLKYGEPLPKDKQV
VNAFITKGSLTDYPKKDFQKLDIKTFITKLPGYSAQLLTFGFMISFLVII
SAIIIGIFMYILTIQKAPIFGIMKAQGISNKTITTAVLMQTFFLSFLGSG
LGLLGTWLTSLLLPTVVPFQSNWFLYLAIFVSMICFALLGTLFSVFNIIR
IDPLKAIG
>SPy0230 putative ABC transporter (ATP-binding protein)
MKTARFFWFYFKRYRFSFTVIAVAVILATYLQVKAPVFLGESLTELGKIG
QAYYVAKMSGQTHFSPDLSAFNAVMFKLLMTYFFTVLANLIYSFLLTRVV
SHSTNRMRKGLFGKLERLTVAFFDRHKDGEILSRFTSDLDNIQNSLNQSL
IQVVTNIALYIGLVWMMFRQDSRLALLTIASTPVALIFLVINIRLARKYT
NIQQQEVSALNAFMDETISGQKAIIVQGVQEDTMTAFLKHNERVRQATFK
RRLFSGQLFPVMNGMSLINTAIVIFVGSTIVLSDKSMPAAAALGLVVTFV
QYSQQYYQPMMQIASSWGELQLAFTGAHRIQEMFDETEEVRPQNAPAFTS
LKEAVAINHVDFGYLPGQKVLSDVSIVAPKGKMIAVVGPTGSGKTTIMNL
INRFYDVDAGSITFDGRDIRDYDLDSLRQKVGIVLQESVLFSGTITDNIR
FGDQTISQDMVETAARATHIHDFIMSLPKGYNTYVSDDDNVFSTGQKQLI
SIARTLLTDPEVLILDEATSNVDTVTESKIQRAMEAIVAGRTSFVIAHRL
KTILNADHIIVLKDGKVIEQGNHHELLHQKGFYAELYHNQFVFE
>SPy0280 bacA, putative undecaprenol kinase (bacitracin resistance protein)
MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKAFIEMFN
IVIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSIL
IAVPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKRNAQQEPAVTELARM
SYKTAFFIGCFQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIP
TMFGYSGLKAVKFFLDGHHLDFAQVLILLVASLTAFVVSLLAIRFLTDYV
KKHDFTIFGKYRIVLGSLLLIYSFFKFVF
>SPy1906 hsdM, putative type I site-specific deoxyribonuclease
MAEKTTSLRQALWHSADQLRGQMDANDYKNYLLGLIFYKHLSDKLLLAVC
DNLEKHFNTFTEAQKIFEDAYQDEGLKDDLISVVTGDLGYFIEPTLTFEK
LIQDVYHNTFQLESLAQGFRDIEQSGEDFENLFEDIDLYSKKLGSTPQKQ
NQTISNVMKTLNEIDFEAVDGDTLGDAYEYLIGEFASESGKKAGEFYTPQ
AVSHLMTQIVFLGREDQKGMTLYDPAMGSGSLLLNAKKYSNQSDTVSYYG
QEINTSTYNLARMNMMLHGVAIENQHLSNADTLDADWPTDEPINFDGVLM
NPPYSLKWSATAGFLTDPRFSSYGVLAPKSKADFAFLLHGFYHLKNTGTM
AIVLPHGVLFRGAAEGKIRQKLLEQGAIDTIIGLPSNIFYNTSIPTTIII
LKKNRTNKDVFFIDASKEFDKGKNQNTMTDNHIKKILDAYKSRDNSDKFS
YLASFDEIIENDYNLNIPRYVDTFEEVPVKPLPELAKQLSDIDQEIAKTN
AKLDQLMKQLVGTTKEAQDELDTFRN
>SPy1904 hsdR, putative type I site-specific deoxyribonuclease
MGNQTKTELELEKELIHLLETGESQWTYRKELKTEDALWDNFFKILAQNN
TQYLNEEPLTASEKEQIKNQLNFVNYYEAAKWLAGENGIAKVQVQREDAK
LGTIRLEVVKADNVAGGTSVYEIANQVAFSGSRDRRGDVTLLINGLPMIQ
IELKSQNHQCIEAFNQVKKYDKEGQFRGIFSTLQMFVVSNKTDTRYIAAA
KENKLNPNFLTQWVDQNNKPQKDLFAFAKEVLSIPRAHQMVMTYSVIDDD
KKALILLRPYQIHAIEAVAEASRHRKSGYIWHTTGSGKTLTSYKVARNIL
QIPAVEKSIFVIDRKDLDNQTASAFQSYAQNDIFDVDETEDTRQLIKNLE
SSDRRVVVTTIQKLNAMISQMESYDTPKFKKLKERLAHLNVVFVVDECHR
AVTPERQRYLTNTFRNSRWYGFTGTPIFVENKRAQLGDLAQTTEQQYGKC
LHQYTVKEAIHDKAVLGFQVEYKTTIPDMPEDSIPEEAYDHEEHMLAVLD
SIINQSRKKLGFNNGIGQTFEGLLTVKSIARAQAYYDLMKKVKAGETDLV
ISKKVKEKLPDFPKVAITYSITENDNASISRQDKMTKNLEDYNHLFGTNF
TIDNLQGYNRDLNDRLARKKDKFKDRHEQLDLVIVVDRLLTGFDAPCLST
IFIDRQPMKPQHIIQAFSRTNRIFESRKHYGQVVTFQTPLRFKEAVDKAL
SLYSNGGENDVLAPSWEEEKARFFEKVTVLKNIVPDPDAFPTIESAQTAF
LKQYAKAFQAFDKLFASVQVYSDFNETLLSEVGLSDEVIDTYKGTYQNVI
AEIRKRREDDEAIPEINIDYELESVQMDDINYHYILTLIQAFVDQEQEAL
QERLNDNPMDQYIQDLAKSNPAMADSLAELWQDIQKEPKAYEGKSIVYEL
DNLIGDKIQRAIKHFADQWKADPDKLAFVATNYHSANSTKQVGMSTLKES
LDYQAYKEKQGDSAMNKLKYKSQFERELVQFIRDQIQPLKGH
>SPy1905 hsdS, putative type I site-specific deoxyribonuclease
MTKSKQPQYRFDGFEGEWEEKELGDIVQITMGQSPSSQNYTTNPSDYILV
QGNADIKNGYVFPRVWTTQITKQADKGDIILSVRAPVGDVGKTNYHVIIG
RGVAAIKGNEFIFQILKYLKEIGYWKRISTGSTFDSISSSDIKYAKIQIP
SLPEQEAIGELFQMVDQLIQLQDQKLATLKEQKQTFLRKMFPAQGQKVPE
IRLQGFKGEWEEKKLREVSTHRSGTAIEKYFDSEGEFKVISIGSYGTNNL
YVDQNIRAVSNELTNSKLVASGELTMVLNDKTANGAIIGRCLLITENNKY
VVNQRTEIIRPDINISSYYLFHYLNGEFRNGIIKIAQGGTQIYVNYSSVE
QLKINIPTLKEQEAIGNFFQTLDQQIAQSEEKLTELKALKQTLLNRLFV
>SPy0616 murM, putative peptidoglycan branched peptide synthesis protein, serine/alanine adding enzyme
MYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERISFYENGV
QVAAAACLIRKLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKR
ALFIKIDPSLVIKQTLEGKESKENDVTLSIIAFLKKLGVEWSGRTKELED
TIQPRIQANIYAKDFDFDSLPKKAKQSIRTATNKGVNVTIGGSELLDDFS
ALMKKTENRKGIILRGKSYYQKLLGIYAGQSYITMASLDLPEQKKLLIQQ
LDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLATGQTRIPL
AATLTLIYGETSENLYAGMDDDYRNYQAPLLTWYETAKEAFKRGCRWHNL
GGVENQQDGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAILTYNLRKKL
RSTTNGTN
>SPy0615 murN, putative peptidoglycan branched peptide synthesis protein, alanine adding enzyme
MALIEISQEQFDHYCHSLVHHSFIQTSEMASLMAKRGAKPQFLGLEKDGE
LKVAAMVFSQKVAGGWRMELNAGPNTNHPEELEHFYTQLKDYAKQKDVIE
LILKPYDNYQSFDTDGIPISRPNTDLISLLTALGYKHDGLKTGYPEGEPV
WHYVKKLEGIDSSRLTRSFSKKGKALIKKANTFGIKLRQLKRDELHHFKE
ITEATSDRRDYLDKSLSYYQDFYDSFGDSCEFMVATLNFEDYLNNLKQRQ
LQLATSINKVKGDLGKNPHSEKKQNRLKELSSQFETFQVRISEALHFLEE
YGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKFYSPALLQEHAMLKAIH
KGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCYPFPIKYHF
IRLAKKLLNRY
>SPy0745 sagH, ABC transporter (ATP-binding protein)-streptolysin S associated ORF
MVLFHLIKKESLQIFRNRTALLMMVIFPILMIVILSFAFKSSFNTATTVP
KLTIRYQLEGEKTDYQKNFLAFLKVLNQKLHLETKPSNSLEKDRQRVSEG
ALTAVLEVKKNQTIKVITNNINQQNADLINMLVKNYVDNAKTYDSIAALY
PQQLNHIRKRSVDYVKVSSIQTSKGMTSADYYAISMFTMITFYSMMSAMN
LVLSDRQQRITNRIHLTGVSPSFLVFGKLIGAMLATTVQLSLLYIFTRFV
LRVNWGTNEWMLIGITASLVYLSVAIGIGLGISIKNEAFLTVASNTIIPI
FAFLGGSYVPLTTLHSSIINQLSNISPIKWVNDSLFYLIFGGQYNPIPVT
LIVNISIGTIFIILALIGMRKQVTT
>SPy1914 salB, putative salivaricin A modification enzyme; amino acid dehydration
MIKRNELKLEYQQHQFYEYFNSIFDYDILDTSIRETSEVLRKKTHKLFYS
EFENQLFETIMFLSMKTLVLDINHFSKEIENKSEAYEQYIQQIREENGIN
HFFDRYPYLLKQINKEVGLIEESYSLLFDRFLEDLSEIKSCFNISEPLSN
VAFSLGDSHSKKQTVVKIAFKEKSVYYKPKSYHSHSILLELTSLLKSSNI
PSFSLPKSLVKADYCWQLGVAYTSSNKDEVAKIYFKYGVLAAFSEIFSIT
DLHMENVIVSGGDLYLIDVETFFQRKLNVQNQNFEGITVDTYQRIYETSL
SNGLFPVQFEKNSAPNVSGISRKGGKRQKGKYELINKNRGDLKLVKVDYF
QEDRFNIPTLNGKVVEPLDYANEIISGFRECYIFLLSQRSKIKEIVEGFP
ELKSRVPFRNTSDYGKFLQASTNPKYLFSEKKRKNLFSILYETKHIEHFI
VDNEIKDLMNGDIPYFSMDTRGNVYNSVGTLIGNLGDTTSLFDSITILND
ERLKFTCELLEIVLKKPIKHWEREKGKSYQFLSISSEHYLL
>SPy1912 salX, putative salivaricin A ABC transporter (ATP-binding protein)
MKQLVLKDVCKKYPNQLNYALDHINLIVEKGEFVAVMGRSGSGKTTLLNV
TSIIDKIDSGNIYCADKEISTFSDKEATNFRKNDIGFVFQDYMLLDSLTI
RENISVALSLKNIDSSKIDDLINSYAKRFNLYEQLKKYPYQLSGGQRQRV
SIIRAIIKEPEIIFADEPTGALDLKSSEETMMILSEINKTEKVTILMVTH
DVLSASYADRVILLKDGKLHMEIDKKDCGESFYDVISQALSDRGE
>SPy1911 salY, putative ABC transporter (permease) associated with salivaricin lantibiotic
MIWSITKSNIKKNFSLYRIYFLATIGLLSIFIAFLNFISDKIITEKIGDS
GQALVIANGSLIFLIVFLVVFLIYFNNFFVKKRSQELGVLAILGFSKREL
TKLLTLENLVILVLSYLVSLLLGPTLYFLAVLAITHLLNLTMEVQWFITV
NEIIESLGILVVVFLINVITNGLIISKQSLIEFVNFSRKAEKKIKIRKVR
AIIAITALLLSYILCLATVFSSTRNMLLSIGMVPVSLLIIVLVVLGTVFT
IRYGLAFVVSLLKENKKRLYRPLSNIIYPKFNYRIATKNKLLTVLGGLLT
VTVSVAGMMVMLYAYSLNGIERLTPSAIEYNVESENGQVNVTTILENDQV
SLVDVGLLRLNTIPEVTITDSGQTIPYFDIINYSDYKELMKAQGRTNSIE
GSKSLPLLINYYPTEISLGKTFNLGNAYDVTVKQVSTNNVFSFSTSVTTL
VVSDKLYAKLSSRFPEKEMTIRTFNGTSIRSSEAFYNQFSMVPDVISSYS
KEHTVKTANIATYIFITFLSILFIICTGSILYFTSLIEIMENKEEYGYLS
KLGYSKKMIHRILRYETGILFLIPVFIGIVNGGMLLIYYKYLFMDTLVAG
NIIMLSLLLCLLFFLIIYGTFYVLTLRLVTSIIKN
>SPy1085 srtF, ABC transporter (ATP-binding)-lantibiotic associated
MLKIQNLKKSYGKRTILNNVNMNIPKGKVYALIGPNGAGKSTIMKILTGL
VSKTSGSIIFEGREWSRRDLRKIGSIIEEPPLYKNLSAYDNMKVVTTMLG
VSESTILPLLNKVGLGNIDKRPVKQFSLGMKQRLGIAISLINSPKLLILD
EPTNGLDPIGIQELREIIESFKSEGMTIMISSHILSEVEHLADFIGFIYE
GKIILEKEYDGSENLEELFNNQILFEKRR
>SPy1084 srtT, ABC transporter (ATP binding)-lantibiotic associated
MIKAQLKNLIKTIHLVKEAGFSLNGSLYMELLHDFTHDELVHNPIIESTV
DTIQSVEFERVSFSYNGKDNVINDISFSIKAGERLAIVGGNGSGKSTIFK
LACGLYDNYEGNIYINGINLCSIQKKSYYKRISALFQDFLKYELTLRENV
GLGELSKLYSDESYNTSFFTTSWDSENELRLEDIYIRYSDGKFHFTTIDE
SIKRD