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# Tropheryma whipplei str. Twist, twist

>TWT047 two-component system response regulator
MLELVRIVAPAIFGNSALHAGSKFMSQTKILVVDDEANIRDLLAASLRFA
GYGVVTAGNGAGAVSAVLAEEPDLIIMDVMLPDMSGFAATKRLREAGFRC
PVIFLSARDSTEDKITGLTVGGDDYVTKPFSLDEILARVAAILRRTKIDD
VDATIRVGDLVIDQNSNEVFLKGNLIDLSPTEFKLLRYFMLNPNRVLSKS
QILGHVWDYDFDGDSSIVESYISYIRRKLAAYSSETIIHTKRGFGYIMRT
R
>TWT774 unknown
MNEFIFFTLKVGFLGLLWIFVLCSIVILYKSLPKGRDNLATPRISSKKFS
PSVGAKMVTVKTECSEQKIPIKQPRMLIGRTPDCQIALSDRFSSGHHAEL
VLTESGWKVRDLGSSNGTFVDGKRIPSGQAITLRIGEELKIGSSAIRLS
>TWT090 protein phosphatase
MLRAVSNRSTGSDDYIVSGKFSISWASLSHVGHHRESNEDSYSAKPPLWV
VADGMGGHACGDIASGVVTSFLSAISSDFVSPQDITGALRQALASLAKKI
GSTTAGTTLSGIGLSKVDNQPAWLVLNLGDSRVYCIESGKIRLLTEDHSI
VHEMIKSGQITPEEAAIHPYNNIITRAVSFNSEPIPDFSFLPLRSGVRFI
ICSDGLTKELNDAQIETHATRGSPREAAESLLYAALSAGGRDNITIILLD
VHDK
>TWT772 unknown
MSSQTHGPEPCASTNSATRAGQINPRNKFAIVNNTIDPQEWSMRVGIGIL
ERIEQSIAKIVDLVFTKTFRSQIQPTELTSALKHKIDSTACLVPNRRSSD
APSHYVIEVSPRGGEHILSRADQLAKELSEFAKEHVRVQGYRYPGGIDVT
VVPSKNLSRGFTIEVVNRSVAWRAFLIIGDKRYPIEQSVIIGRGLSADVR
LADSSVSRQHAKIDVDGEKAMIVDIGSSNGFKVNGKRCTKATLKNNSLIN
LGRQKILFVFLPIFD
>TWT597 putative serine/threonine-protein kinase
MIPFFNKHTRSTDDKDTEKARQIIGNYRVIKTLHESDRAVIYLAQEISGD
PGMVARQSFMDPGELVNLVALKMYRAGVTSEHIAIEADALDSLRGPGVVE
LRDVLNLPDKRGLVMRALHGPALVDLWETRGSLSPGEMVTILASLVATLA
RISSAGYAHGAVWPGNIRFDDIGRPVLTGFSSARKHAPPNADWLDFYSLL
RGCAVLINEKQEQMLQISAGVRKRLDPFDPELPAWVEASLFRLADPQPLR
FEHPISLHDTSGYNLRESPNPVDSNRQTGKSQIILKLTDNKYVAAILGKL
KRPSVLFIALFVSVFVVLLMVIPNNSGEDNERKSEKPGYVKSKGTFKKPS
KTGKSRKRSEVSEKLRKNMEECLASKDADCVDVMSEINADLGEKLDEG
>TWT234 unknown
MRGVSVSNVPEGETTLVNLSAALSYSQPLTHEERQVISALPPGAGLLIIR
RGGYSGSRFLLDTQISIAGRHPASDIFLDDVTVSRRHAEFKRDGDIFRVV
DLGSLNGTFVMQQRVDNAVLCDGFEVQIGKFHLTFFTSKALKG
>TWT291 two-component system response regulator
MLRVCRSATPADFNDTLCPQGRYLMRNESFPLQTADLSPCAVVAEDESII
RMDINDIMSDAGYKVVAEAGDGETAVALTLEHNPDIVVMDIKMPFMDGIT
AAEKISSRSAVVLLTAFNQQELVERAVDAGVMAYVSKPFSRGNLIPAVAV
ALERFRKINSLQKQLDDASTHLEVRKLTDHAKGLLCKHMGLSEPEAFRWI
QKMSMNRRISMKEVSKSIIAQLAGK
>TWT628 predicted secreted protein
MCIPRNNEIGFEVLMHCGLRSKRFRIGLLFLFLSCTLAGLLGLAPSGMLI
EQPGPILPLVGFGDKDVVKNKNLKTKTGKLIGLSVLLVGTPEARLPVAYV
ALSMFDRHLNIVPLDEVYPPGTSAEHFGQVQGYLMHTSRDTAVLTAMQRL
GIPVLKRVVIRRVWKGMASEGKLFMGDEILSVDNKPVPSLEVLRGAIQNR
PLKLEILRSGRVVLIELIPRVDGDRALLGIDVFEKPVSKTSIEFVDGDVG
GQSAGLMFAIASYELLSGQGITDGLYISGTGALHPDGRVLEIAGSVQKMW
AAYRAGSRIMLLPRENCPEIRSVAPHDMFAYSVSSFDEAISTIKNLKVGK
KELKNRCA
>TWT632 two-component system sensor histidine kinase
MPLPDNLSKECKLGKLEAEWIGLILNEGNLLAGLANSDVIFWLYKPNGQF
ISVEHIRPQGVFTLFHRDFVGKTCPETWAGALKKAYSSCKMIDLVESTDY
GPVKIVVTPVKMNYLGREKKIVPFVVTSHGVISDFNQSIQYVYTECAQEL
FGMLTRGDFPRSDFPIGSHFGLPRPNDGLIRLNQDGDVIHASPKAVSVFK
TLGILNEIEGENLSKLVLSLVEDNFKTDEALPLVVSGRADWISEIQVSGA
NVVFRSVPIRDGNRRNGAIVLCRDVTAQRFQHTQLMTRDATIREIHHRIK
NSLQTVASILRLQSRRSDSEIVRAEFADAVRRILGVSEVHDALSRDLSEN
LNFDDFFPKLVKLIISLAELDKNGIDLRIKGRFGFLDSKYAVPLMLVLTE
LVANAVEHGFSGTHDQLVIYGQRTDDAMHVLVSDNGVGIDLSRLGKGLGT
RIVNSIVDAEFSGRISWHRNPYTSDIPEVSDLLPARGTTVTLSIPFGQLT
RSTI
>TWT046 two-component system sensor histidine kinase
MSAKFPSKLYRLVARSSIKSKVVTLVALVLAFSFTAVGIGTTLVIKNEMI
KTIDEQLIHISGTFPLFESSFEVFSPGRASYKAHIYKFDGTLIWPIGENP
SIEFDRKIDITLYNEKGNTPFTLHSISRQKKYRMLLQPLETGSGQEILAY
YLPQSGTENTANFYQRSYIWFSLAVFAIAAYIVYLITAHTLSPLYALEKT
ARAFARGDYSRRIRSEYVSAEILNLNKSLNSMLDSLEKALGERDKTLGEM
KQFLADASHELRTPLVSLRGYAELYRIGALKGKEDIDNAIERIEKEAIRM
GTMVEDLLSLTRLEKATDLVPVDVKYLVQESVIDMNVLEKTRKITTGIPK
RQSCMILGNENMLRRLLANLINNALHYTPPGSPIEIVLRTDKTDVVIDVR
DHGPGVPRQLHDKVFKRFWRSDASRARNSGGVGLGLSIVASIVKVHKGTI
EILRTRGGGATFRTRIPKLVNKHRSGSSSHSLTR
>TWT777 pknA, serine/threonine-protein kinase
MSFDAGTVLGKRYRLIARIAIGGMGEVWKAHDEVIQRHIAIKILKEEYVG
SRDFIERFRTEARHAAIVNHVGIANIFDYGEEKGIAYLVMELVDGEPLSA
VLERERMLPVEEVLRIVVQISRALQAAHSAGLVHRDIKPGNILISESGLV
KITDFGIARIGDQVPLTTTGQVMGTVHYLSPEQAAGKKADAMTDVYSLGV
VAYECLTGKRPFVGDSQVAIAVAHVGDTPANLPKDIPRPVARLVLGCLEK
QPQRRPKSAGNLADAASALLKDDLAEAARAYPPLAASGEQNGSGQVLDNQ
TKAISTTTSLYSKLGQFDTRLLGQTMEFNGGSESKPARGKWVLPVVGTIT
ALAVIVGGGALAIIVTGNRGGLTETKTGVSTHDVTQTAASYIPTIVSPNT
RPAGNTVVIDPGKYVGLSFDGVQKALFALGVGIKRLSAGPAPSADKAGLV
ESISPTGTLTIPAVIDVKVYGPPVMTPPAFAPRLIGTPKIGGSVYVSWPV
YTSCPAGSQVTLYRISVDGAVLQGPGTVGADTTQVELLLIQNEASVKYSA
DCSVPGKNQTFNSGFSDVLKISTNGSHTPSIASSG
>TWT275 relA, GTP pyrophosphokinase
MHRSFVMKIANISLFSRLFSQYRTTGIDNILKVIAKHHPKADLSGVTLAY
KIASECHKGQKRYSGEEYISHPVAVAEILSDLGMGPNGVSAGLLHDTVED
TDFTIDQVSETFGQEVALLVDGVTKLDRMKYGVNVQSESWRKMIVAISKD
IRVLVIKLADRLHNARTWGFVPIESAKRKARETLEIYAPLSGRLGIQNIK
TELEDLSFMVLEPKIYQEILELVNKRSPRREKLINEVRSGIDDELKLLRI
RGKVSGRPKEIYSIYQKMVLRGHSFSDIQDLVAFRIVVPTLRDCYAVLGS
MHTRWTPMQGRFKDYIATPKSNFYQSIHTTVMLDGGFPVEIQIRTPEMHR
QAEFGIAAHWKYKEKLRSPTVAFRKTAALDHESVYISRIADWQESSDSNE
LLENMRYELSVKDIYVFTPAGKLVGLPAGSTPVDFAYAVHTEVGHRTVGA
KVNSSMVSLDTPLSTGDVVEVLTIKSANYSPNKNWLEFVKSTRARNKIKS
FFTKSRREEAIELGKNALLKCFRKRNVSVKYVQKRLPELLSSLRFSDIND
VYRAVGEGRLKALAVVDTLSKLIHDTVEDETSPIQVIRTDKPATDKPANE
PSVLVRGIHDILVRLARCCTPVPGDEIIGYVTRGTGVSVHIMSCGNISHM
PEKDSRLVKVEWSRSAQTKPFRVSIQIDGLNRPDLINDITKVFSEYRINI
LSANLSTNQHRASNKFVCEAYDVSRLEKVMSEIRKIDSVYDCYRA
>TWT595 typA, GTP-binding protein TypA/BipA-like protein
MITKDIRNIAVVAHVDHGKTTLISAMLQQTSDSTTAEDRVLDSHELEREK
GITILAKNTAVTYKSSGRSVTLNIVDTPGHADFGGEVERGMSMVDGVVVL
VDASEGPLPQTRFVLKKALLKKLPIVLAVNKTDRSDARIDDVVSEFQDLL
ISLAEEINDPALYSILDVPIVYVSGRAGRASINKPDNGQLPDRNNLDDLF
EKIISYIPAPEYDKNAPLQAHVANIDASAFLGRLALTRIYNGSISKGQTV
CWVNASSKQRVNVRVTELLKTVALDRVPVPSVSAGDIVAIAGIPDVMIGD
SICDPDDVRPLPGISIDEPAISVVIGVNTSPLAGGVPGHKLTATQIKERL
DRETIGNVSIRVIPTRGTDAWEVQGRGELALAVLIEQMRREGFELTVGKP
SAVTRIVDGSLHEPYELLTVNLMDEYFGSVTKLLAERKGRVESVISNAGW
TNADFVVPSRGLIGFRTEFLTITRGTGTANAIFHSYAPWSGQINQRAQGS
AVADRAGHVTSYAILGLQERVLFFVSPSEQVYEGMVVGRNSRPGDLNVNV
TKGKKLTNTRSSTAEELEKIVPARHLSLEECLEFAGPDECVEVTPEAIRI
RKIELSQSVRSKQR