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# Streptococcus pyogenes phage 6180.4

>M28_Spy0305 SAM-dependent methyltransferase
MTDLDRRKVMLKRPIHLSHDFLAEVVDKSSVVVDATMGNGNDTAFLAQLA
KKVYAFDVQEQAIRKTSERLAQLGLSNAELILAGHEAVDQYVTEPVRAAI
FNLGYLPSADKSIITLPNTTLQALSKLLTLLMVGGRIAIMVYYGHDGGSL
EKDALLDFVKQLDQRKVSAMLYQPLNQVNTPPFLIMLEKLADV
>M28_Spy1479 3-oxoacyl-[acyl-carrier protein] reductase
MEIKGKNIFITGSTRGIGLAMAHQFASLGANIVLNGRSAISEELVASFTD
YGVTVVTISGDVSEASEAKRMVNEAIESLGSIDVLVNNAGITNDKLMLKM
TEEDFERVLKINLTGAFNMTQSVLKPMIKARQGAIINVSSVVGLTGNIGQ
ANYAASKAGMIGFTKSVAREVAARNICVNAIAPGFIESDMTGVLPEKMQE
QILSQIPMKRIGKAQEVAHLASFLVEQDYITGQVIAIDGGMTMQ
>M28_Spy1343 SAM-dependent methyltransferase
MVTKEVGHDFLARLGKKRLRPGGVEATNWLIEQGQFSQDCHVLEVACNRC
TTAIELAKTFGCQIDAVDLNPKVVKEAQERVTVEGLTRHITVSQANALSL
PFPDNHFDIVINEAMLTMLNAKAKEKALNEYWRVLKPGGRLLTHDVAYED
PKTRQVLDELRQTIHVNVAPLSLTGWQALYQEHGFSQVTYHHGKMSLMTP
RGMIKDEGLMNTLNIMRRGLKKENRQQFLKMRRFFTRTGKNLCYIAVKSV
K
>M28_Spy0513 acetoin dehydrogenase
MTKKYEVEDMSKVAIVTGAGQGIGFAIAKRLHADGFKIGILDYNEETAQA
AVDKLSPEDTVAVVADVSKRDQVFDAFQKVVDTFGDLNVVVNNAGVAPTT
PLDTITEEQFEKAFAINVGGTIWGSQAAQKHFRELGHGGKIINATSQAGC
EGNPNLTVYGGTKFAVRGITQTLAKDLASEGITVNAYAPGIVKTPMMFDI
AHEVGKNAGKDDEWGMEQFAKDITLKRLSEPEDVANAVGFLVGDDSNYIT
GQTIVVDGGMVFH
>M28_Spy1283 phage protein
MMTPETVCQEKGIDLVYFDGRGTNIPGMFNKKHNVIAIDTYLDGIYKHKV
IYHELGHREHTASYYKLNKEKAELQADRCMIHHLLKEELSYWDNMEDFNY
IQFMEKYELTSIADEVMVKEEFKNLI
>M28_Spy0258 methyltransferase
MLQRDLVNTTGFLRMIMKHNYEKFASVYDAVMDDSLYDLWTDFSLRHLPK
SKGRNRLLELACGTGIQSVRFAQAGFDVTGLDLSQDMLAIAKKRAQSAKK
KIDFIQGNMLDLSQVGQFDFVTCYSDSICYMQDEVDVGDVFKEVYDVLAN
DGIFIFDVHSTYQTDECFPGYSYHENADDFAMVWDTYADEAPHSVVHELT
FFIQEDDGRFSRFDEVHEERTYELLTYDILLEQAGFKSFKVYADFEDKEP
TKTSKRWFFVAYK
>M28_Spy1331 hypothetical protein
MDLSTVIKKTEDLGITILFCNMPKTKGRYDSTLEKPCIYVDKSLSDIEKI
NIILHEKMHFTKNDQSNCLSYISSYSHHIENQAEKDRILDFMNLINEEYP
IDESFNYINYMKNACVPEKYESYIKNLAKEFYLRNHRKES
>M28_Spy1077 thioesterase superfamily protein
MSDLTQEMTLNVISIFDNYQIELAEKGHLILSTEVTETALNYYGNAHGGY
LFTLCDQVGGLVARTTGVESVTLQANANYLKAGHKGDKLMVEGRLVHGGR
TTQVVDVTIHNQTGALLTKTSLTMFVTGRRHNG
>M28_Spy1500 pyrazinamidase
MMRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQGDYIFF
AIDCHDQNDPWHPESKLFAAHNIKGTTGRHLYGPLAEVYSYMKQHPRVFW
IDKRYYSAFSGTDLDIRLRERGITQLVLTGVLSDICVLHTAIDAYHLGYQ
LEIVKSAVASLTKESYEWSLAHFEQVLGAKLINDY
>M28_Spy0421 long-chain-fatty-acid--CoA ligase
MLTKLEYWAKQCPNKKAIVADQISLTYQELWQAVLIKDQTIKDSVPYIIS
HSRYLNQLLSFLRGLKEGSCPIILHPNISGTFQQQIKHVDSELLKKADFA
VLSSGTTGKAKLFWRCLSTWTRLFDYQNKVFGMTGNSCLFLHGSFSFTGN
LNLALAQLWAGGCLVLSQKLSLKTWLSLWQAKKVSHLYLLPTYLNRLLPY
LTKNNMTATHLLTSSQMISQELLRHYYKKFPQLEIVIFYGASELSFITWC
NGRAAVKINGLVGQPFPDVSISFKDKEIFVETPYSVEGMSQPYSVSDLGK
MSPAGLILEGRQDDWVNQRGVKCHLPSLVELAHQAPNVKEAHALKIGKGE
NETLILVLVLTKKDCLAPIKDFLALYLNSGQLPKYYLVIDCLPLKDNGKI
NREVLLNKIPKQWLS
>M28_Spy1388 D-beta-hydroxybutyrate dehydrogenase
MTHTKEVAFITGAASGIGKQIGETFLKEGKTVVFSDINQEKLDQVVADYT
KEGYDAFSVVCDVTKEEAINAAIDTVVEKYGRIDILVNNAGLQHVAMIED
FPTEKFEFMIKIMLTAPFIAIKRAFPTMKAQKHGRIINMASINGVIGFAG
KSAYNSAKHGLIGLTKVTALEAADSGITVNAICPGYVDTPLVRGQFEDLS
KTRGIPLENVLEEVLYPLVPQKRLIDVQEIADYVSFLASDKAKGVTGQAC
ILDGGYTAQ
>M28_Spy0348 short chain dehydrogenase
MTKVVLVTGCASGIGYAQARYFLRQGYHVYGVDKSDKPDLSGNFHFIKLD
LSSELSPLFKVVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINFFAT
VKLTRHYLRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQ
LALDYAKDQIHIFGIAPGAVKTAMTASDFEPGGLAEWVARETPIGRWTEP
DEVAELTGFLASGKARSMQGEIVKIDGGWTLK
>M28_Spy1052 D-alanyl carrier protein
MSIEETVIELFDRLFMEDVSEMMDEDLFDAGVLDSLGTVELIVELESTFN
IKVPISEFGRDDWNTVTKIVQGVEELQHA
>M28_Spy0964 ABC transporter ATP-binding protein
MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKTTLIKLI
NGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSD
FYSDFDKSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYV
LDEPIGGVDPAARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFL
KQGRLFLSGNADDLRQEYQQSIDSLFRETYKV
>M28_Spy0021 acpP.1, acyl carrier protein
MTRQEIFERLINLIQKQRSYLSVAITEQTHLKNDLAVDSIELVEFIINVE
DEFHLAIPDEDVEDMVFMGDVLDYLVQRLT
>M28_Spy1482 acpP.2, acyl carrier protein
MAVFEKVQEIIVEELGKETEEVTLETTFDDLDADSLDVFQVISEIEDAFD
IQIETEEGLNTVGDLVAYVEEKSK
>M28_Spy1054 dltA, D-alanine-activating enzyme
MIKDMIDSIEQFAQTQADFPVYDCLGEHRTYGQLKRDSDSIAAFIDSLAL
LAKSPVLVFGAQTYDMLATFVALTKSGHAYIPVDVHSAPERILAIIEIAK
PSLIIAIEEFPLTIEGISLVSLSEIESAKLAEMPYERTHSVKGDDNYYII
FTSGTTGQPKGVQISHDNLLSFTNWMIEDAAFDVPKQPQMLAQPPYSFDL
SVMYWAPTLALGGTLFALPKELVADFKQLFTTIAQLPVGIWTSTPSFADM
AMLSDDFCQAKMPALTHFYFDGEELTVSTARKLFERFPSAKIINAYGPTE
ATVALSAIEITREMVDNYTRLPIGYPKPDSPTYIIDEDGKELASGEQGEI
IVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTEDNILLYGGR
LDFQIKYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIV
VKDGVKERFDRELELTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKI
DIKTLINEVNNR
>M28_Spy1478 fabF, 3-oxoacyl-[acyl-carrier-protein] synthase
MTFKRVVVTGYGLTSPIGHDPETFWNNLKAGQIGIGPITKFDTTDYAVKN
AAEIQDFPFDKYFVKKDLNRFDRYSLYALYAAKEAINHADLNIEMVDSDR
FGVIVASGIGGIAEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMS
LKAQGVCKSINTACASSNDAIGDAFRAIKFGTQDVMIVGGSEAAITKFAI
AGFQSLTALSTTEDPSRSSIPFDKDRNGFIMGEGSGMLVLESLEHAQERG
ATILAEIVGYGNTCDAYHMTSPNPEGLGARKAIHLALQEAGIEASAINYV
NAHGTSTPANEKGESQAIVAVLGKDVPVSSTKSFTGHLLGAAGAIEAIAT
IEAMRHNYVPMTAGTQALSEDIEANVIFGEGKETAINYAISNTFGFGGHN
AVLAFKCWEE
>M28_Spy1754 hutI, imidazolonepropionase
MLKKEVFMVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKD
GLIVALGSGEPDAELVGPQTIMRSYKGKIATPGIIDCHTHLVYGGSREHE
FAKKLAGVSYLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHG
VTTVEAKSGYGLDWETEKRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYK
GNPKAYLDVIIKDMLPVVKEENLAEFCDIFCEKNVFTADESRYLLSKAKE
MGFKLRIHADEIASIGGVDVAAELSAVSAEHLMMITDDGIAKLIGAGVIG
NLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPTANMQFVMQL
GCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNID
YPFYFFATNLIHQVYKKGQLTVDRGRIL
>M28_Spy0503 idnO, gluconate 5-dehydrogenase
MENMFSLQGKIALITGASYGIGFEIAKAYAQAGATIVFNDIKQELVDKGV
AAYRELGIEAHGYVCDVTDEAGIQQMVSQIEDEVGVIDILVNNAGIIRRT
PMLEMAAEDFRQVIDIDLNAPFIVSKAVLPSMIAKGHGKIINICSMMSEL
GRETVSAYAAAKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLR
ERQADGSRHPFDQFIIAKTPAARWGTTEDLAGPAVFLASDASNFVNGHIL
YVDGGILAYIGKQP
>M28_Spy1671 lrp, leucine rich protein
MCYNGLKTIMKGMAMELKDYFPEMQVGPHPLGDKEWVSVKEGDQYVHFPK
SCLSEKERLLLEVGLGQCEVLQPLGSPWQRYLLDHQGNPPQLFETSQFIY
LNHQQALPDDLVELLQQMIAGLEVILPISATQTAFLCRQAISIKVLRWLE
DLLPTLESDFGLALTMFVGNAWYQVAAGTLRECFEEECQLLTAYLRQQSG
RKLLTFSGLMLWSLLSHHTFLALTRQFHQSLSPQSDMADVVHALWSEHGN
LVQTAQRLYIHRNSLQYKLDKFAQQSGLHLKQLDDLAFAHLFLLKY