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# Streptococcus pyogenes phage 6180.4

>M28_Spy0843 antigen
MFRLLKRACSFLLLFVIYQSFVIHHNVQRVLAYKPMVEKTLAENDTKANV
DLVLAMIYTETKGGEADVMQSSESSSGQKNSITDSQASIEHGVNLLSHNL
ALAEEAGVDSWTAVQAYNFGTAYIDYIAKHGGQNTVDLATTYSKTVVAPS
LGNTSGQTYFYYHPLALISGGKLYKNGGNIYYSREVHFNLYLIELMSLF
>M28_Spy0601 phosphoglycerol transferase
MEMTSLGKNDKEVATVKKFKTLITGFINTRLGFIITLLFCYWIKTLWAYH
TDFSLDLGNIYQVFLTIINPIPLAFLLLGVALYVKNTRAFYICSWVVYII
LNILLISNSIYYREFSDFITVSAMLASSKVSAGLGDSALNLLRIWDIIYI
LDFIILISLSITKKIKNDQRPFNKRAAFAITALSSLLLSINLFLAEIDRP
ELLTRGFSNTYIVRALGLPAFTLYSGNQTYQAQKERNGATAEELIDVKTY
VKGHYAAPDPQYFGIGKGKNIIVLHLESFQQFLIDYKLKEGDKEYEVTPF
INSLYHSNATLAFPNFFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYGG
ENTQFATPSILTQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYFFDSSYF
SKQNSKNSFQYGLNDKYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLK
GESSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLYENSIF
VLYGDHYGISNSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTN
GSIKETFGGEIDALPTLLHILGIDTSQFVQLGQDLLSPQNSQIVAQRTSG
TYMTPEYTNYSGRLYNTQTGLEITNPDEMTIAKTKEIRSAVAQQLAASDA
IQTGDLLRFDTQNGLKAIDPNQFIYTKQLKQLKDISAKLGSESTSLYSKN
GHKSTQKLFKAPSYLELNPVEADAATSELKEDNPKNKE
>M28_Spy1520 putative Fe3+-siderophore transport protein
MKMKKISKCAFVAISALVLIQATQTVKSQEPLVQSQLVTTVALTQDNRLL
VEEIGPYASQSAGKEYYKHIEKVIVDNDVYEKSLEGERTFDINYQGIKIN
ANLIKDGKHELTIVNKKDGDILITFIKKGDKVTFISAQKLGTTDHQDSLK
KDVLSDKTVPQNQGTQKVVKSGKNTANLSLITKLSQEDGAILFPEIDRYS
DNKQIKALTQQITKVTVNGTVYKDLISDSVKDTNGWVSNMTGLHLGTKAF
KDGENTIVISSKGFEDVTITVTKKDGQIHFVSAKQKQHVTAEDRQSTKLD
VTTLKKAIKEADAIIAKESNKDAVKDLAEKLQVIKDSYKEIKDSKLLADT
HRLLKDTIESYQAGEVSINNLTEGTYTLNFKANKENSEESSMLQGAFDKR
AKLVVKADGTMEISMLNTALGQFLIDFSIESKGTYPAAVRKQVGQKDING
SYIRSEFTMPIDDLDKLHKGAVLVSAMGGQESDLNHYDKYTKLDMTFSKT
VTKGWSGYQVETDDKEKGVGTERLEKVLVKLGKDLDGDGKLSKTELEQIR
GELRLDHYELTDISLLKHAKNITELHLDGNQITEIPKELFSQMKQLRFLN
LRSNHLTYLDKDTFKSNAQLRELYLSSNFIHSLEGGLFQSLHHLEQLDLS
KNRIGRLCDNPFEGLSRLTSLGFAENSLEEIPEKALEPLTSLNFIDLSQN
NLALLPKTIEKLRALSTIVASRNHITRIDNISFKNLPKLSVLDLSTNEIS
NLPNGIFKQNNQLTKLDFFNNLLTQVEESVFPDVETLNLDVKFNQIKSVS
PKVRALIGQHKLTPQKHIAKLEASLDGEKIKYHQAFSLLDLYYWEQKTNS
AIDKELVSIEEYQQLLQEKGSDTVSLLNDMQVDWSIVIQLQKKASNGQYV
TVDEKLLSNDPKDDLTGEFSLKDPGTYRIRKALITKKFATQKEHIYLTSN
DILVAKGPHSHQKDLVEKGLRALNQKQLRDGIYYLNASMLKTDLASESMS
NKAINHRVTLVVKKGVSYLEVEFRGIKVGKMLGYLGELSYFVDGYQRDLA
GKPVGRTKKAEVVSYFTDVTGLPLADRYGKNYPKVLRMKLIEQAKKDGLV
PLQVFVPIMDAISKGSGLQTVFMRLDWASLTTEKAKVVKETNNPQENSHL
TSTDQLKGPQNRQQEKTPTSPPSAATGIANLTDLLAKKATGQSTQETSKT
DDTDKAEKLKQLVRDHQTSIEGKTAKDTKTKKSDKKHRSNQQSNGEESSS
RYHLIAGLSSFMIVALGFIIGRKTLFK
>M28_Spy0414 1,2-diacylglycerol 3-glucosyltransferase
MRVGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRDVKRFED
PTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKHYNLDIIHTQTEFSLGLL
GKMIGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLD
GVICPSRIVLNLLEGYEVTIPKRVIPTGIPLEKYIRDDITAEEVTNLKAE
LGIAGDETMLLSLSRISYEKNIQAIINQMPAILAENAKIKLIIVGDGPYL
QDLKHLAMQLEVDKHVTFTGMVPHDKVALYYKACDFFISASTSETQGLTY
IESLASGTPIIAHGNPYLDDVVTDKMFGTLYYAETDLTDAIIDAILKTPV
MDKRLLAKKRYEISAQHFGKSIYTFYLDTLIARNSKEAQKLSLYLNHSGK
SSSLKLVQGAIHLPKRAAKVTAITSVKVVKAPIKLVHAIKDFLD
>M28_Spy0830 glycine betaine transport system permease protein
MLLWPIYLEVMSMPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGV
PLAALLSRSKRWSDIMLQVTGVFQTIPSLALLGLFIPLMGIGTLPAVTAL
VIYAIFPILQNTITGLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVI
MSGVRTSAVMIIGTATLASLIGAGGLGSFILLGIDRNNANLILIGAISSA
LLAIIFNSLLQYLEKASLRRIMISFGITLLALLASYTPMALSQFSKGKDT
VVIAGKLGAEPDILINLYKELIEDQSDISVELKSNFGKTSFLYEALKSGD
IDIYPEFTGTITSSLLRDKPPLSNDPKQVYEDAKKGIAKQDKLTLLKPFA
YQNTYAVAMPEKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGM
QSQYGLQLSVATMEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDD
KQLFPPYQGAPLMKTSLLTKHPELKGILNQLAGKITEKEMQDMNYEVSVK
GADANKVARDYLLKTGLIQK
>M28_Spy0435 glycosyltransferase
MFVIGIPTLNEADNISRLVKQIDEYAVNLGKEIIIINSDSKSTDGTPQIF
LETKTYNTKVSIVSEAKGKGYNVRNIFEYAINHVPNFSGLILIDGDVVSM
KKMWLEKMFIAIESGNDLIIPNYARKSFEGNATNHFIYPMLVKFFKRDMP
YQCISGDFGFSRGLIKDLTLKCNWHKYTLGYGIDIFLTLTAILKSYKIKE
IDLQSKIHKKSFEKIEKIFLEVSQSFFETINDNSLNQDKLRLNINFESHS
RQFIKSSDILSSNDIENLKLRALFLLQEEKQYPHGLSEVEWDGILSNTIN
NIYRYSSEEHSLYLLPLYLLRVYNYLKYN
>M28_Spy1408 division specific D,D-transpeptidase
MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIINFMIIIG
TDQKFGVSLSEGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAI
LDKSFVSASDEKLYVQPSQYETVADILKKHLGMKKTDVIKQLKRKGLFQV
SFGPSGSGISYSTMSTIQKAMEDAKIKGIAFTTSPGRMYPNGTFASEFIG
LASLTEDKKTGVKSLVGKTGLEASFDKILSGQDGVITYQKDRNGTTLLGT
GKTVKKAIDGKDIYTTLSEPIQTFLETQMDVFQAKSNGQLASATLVNAKT
GEILATTQRPTYNADTLKGLENTNYKWYSALHQGNFEPGSTMKVMTLAAA
IDDKVFNPNETFSNANGLTIADATIQDWSINEGISTGQYMNYAQGFAFSS
NVGMTKLEQKMGNAKWMNYLTKFRFGFPTRFGLKDEDAGIFPSDNIVTQA
MSAFGQGISVTQIQMLRAFTAISNNGEMLEPQFISQIYDPNTASFRTANK
EIVGKPVSKKAASETRQYMIGVGTDPEFGTLYSKTFGPIIKVGDLPVAVK
SGTAQIGSEDGSGYQDGGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHFG
PLFWQDVVNPVLEEAYLMQDTLTKPVVSDANRQTTYKLPNFVGKNPGETS
SELRRNLVQPVVLGTGSKIKKVSHQPGQTLTENQQVLILSDRFVEVPDMY
GWTKSNVKTFAKWTGIDISFKGTDSGRVMKQSVDVGKSLKKIKKMTITLG
D
>M28_Spy0739 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase
MKMKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACNKDILKDLSKDYDI
VVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKG
KSGRQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQM
IVDGARNAPKATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNT
EGILCPKCEHILQYRLNTYANLGDFICLNCGFKRPQLDYRLTELTAITHQ
SSEFVIDGQNYKINVGGLYNIYNALAAVSVAEFFGVSPEKIKAGFNKSKA
VFGRQETFTIGDKSCTLILIKNPVGASQALEMIQLADYPFSLSVLLNANY
ADGIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVTGFDDTKIK
QAEKLEQIMEAIEKQESKHAYILATYTAMLEFRSLLADRHVVEKEMN
>M28_Spy0970 phage-associated lysin
MATYQEYKSRSNGNAYDIDGSLGAQCWDGYADYCKYLGLPYANCTNTGYA
RDIWEQRHKNGILNYFDEVETMQAGDVAIFMVVAGVTPYSHVAIFDSDAG
SGYGWFLGQNQGGANGAYNLVKIPYSTTYPTAFRPKVFKNAVTVIGNIGL
NKGDYFIDVSAYQQADLTATCQQAGTTKTIIKVSESLAWLSDRHQQQANT
SDPIGYYHFGRFGGDSNLAQREADLFLSNLPTKKVSYLVIDYEDSASADK
EANTNAVIAFMDKIANAGYKPVYYSYKPFTLNNIDYQQIIAKYPNSIWIA
GYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAGGLDKNIVLLADDSSKV
DIPKIDKPQSQLTFNQKLDTNTKLDNSNVPYYEATLRTDYYVESKPNASS
ADKEFIKAGTRVRVYEKVNGWSRINASQSDQWVEDKYLSNATQV
>M28_Spy0849 sortase
MVKKQKRRKIKSMSWARKLLIAVLLILGLALLFNKPIRNTLIARNSNKYQ
VTKVSKKQIKKNKEAKSTFDFQAVEPVSTESVLQAQMAAQQLPVIGGIAI
PELGINLPIFKGLGNTELIYGAGTMKEEQVMGGENNYSLASHHIFGITGS
SQMLFSPLERAQNGMSIYLTDKEKIYEYIIKDVFTVAPERVDVIDDTAGL
KEVTLVTCTDIEATERIIVKGELKTEYDFDKAPADVLKAFNHSYNQVST
>M28_Spy0437 UDP-glucose 6-dehydrogenase
MKITVVGIGYVGLSIGLLLAKEHDVTFFDIDNKKIDLINKRQSPLKEAAI
NKLLCKAKNINATSSEELAYKDATFIILSLPTNLKFNKLDTSIIEISVSN
ILKINKKATIVIKSTVPIGFTEYLRNRFHYNDIIFSPEFLREGSTIHDQL
YPSRTIVGNESRNSQLFLDILTDISVEKDSPSLLVGSSEAEAIKLFSNAY
LAQKIAFFNELDTFAEMQNLDSKKIIEAMGYDQRIGNSHNNPSFGFGGYC
LPKDIKQLEYHFKEIPAPIITSISESNLLRKIHIAKMILNSSAKTIGIYR
INSKKDSDNCRKSSTIDVAKLLKSSGKDVIIFEPLINQKKFLGCPLINDF
NEFIKYSDIIVANRIDDALRKCNSKVFTRDIFQYD
>M28_Spy1543 hypothetical protein
MFQKLKNLIDRYSWFVFIMMILVLFLNYIYPFDPSLSGLQLEWLIMTQVF
PGLGIVCAMVAIIFKKFNLFVLALILYFALWLKLFLAFSFFTYFLGV
>M28_Spy1602 mechanosensitive ion channel
MTFILHYLEQSHIENIGLTIFKKLVSLIILLLFFAILKRVTNYLFEKTIN
KSFAYSRQSEARKKTLSKLTHNILNYLLYFLLIYWILSLFGIPVSSLLAG
AGIAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDNVTISDIEGSVFGVG
IRTTQIRGFDGTLHFIPNRSITVVSNKSRGNMRALIEIPLYSTVNLSQVT
RIIDEVNQKELPNHPQIVGKPNILGPQNNSNGQFTFRIAIFTENGEQFKI
YHTFYRLYQEALLKEGIQLPTAISYSITSKS
>M28_Spy0408 glucosyltransferase
MKYLSFCVTIALKFHLKEKSMTLLSIIVPCFNEEANILPYFEEMHQLETS
MTNQLAFEYIFIDDGSKDNTLGILRELAARFPNVHYLSFSRHFGKEAGLL
AGLKEAKGNYITVMDVDLQDPPELLPVMYAKLKEGYDIVGTRRQNRQGEP
LIRSMCSNLFYGLIKHLSDTEMVNGVRDYRLMTRQVVDSILELGEVNRFS
KGIFSWVGYRITYLSFENQKRKYGKSRWHFWELLRYSLDGFINFSEMPLT
IATWTGTFSFLISIFAILFIIIRKILFGDPVSGWASTVSIILFMGGIQLF
CMGIIGKYISKIFLETKKRPLYIIKEKH
>M28_Spy0106 sortase
MTERLKNLGILLLFLLGTAIFLYPTLSSQWNAYRDRQLLSTYHKQVTQKK
PSEMEEVWQKAKAYNARLGIQPVPDAFSFRDGIHDKNYESLLQIENNDIM
GYVEVPSIKVTLPIYHYTTDEVLTKGAGHLVGSALPVGGDGTHTVISAHR
GLPSAEMFTNLNLVKRGDTFYFRVLNKVLAYKVDQILTVEPDQVTSLSGV
MGKDYATLVTCTPYGVNTKRLLVRGHRIAYHYKKYQQAKKAMKLVDKSRM
WTEVVCAAFGVVIAIILVFMYSKMTDKKVIKN
>M28_Spy1407 phospho-N-acetylmuramoyl-pentapeptide-transferase
MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHLAKAGTP
TMGGTVFLLVATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDD
FLKIFKQINEGLTAKQKLALQLVGGLMFYFLHVSPSGISSINVFGYQLPL
GIFYLFFVLFWVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQSQF
DVLLLIGAMIGALLGFFCFNHKPAKVFMGDVGSLALGAMLAAISIALRQE
WTLLIIGIVYVLETSSVMLQVSYFKYTKKKYGEGRRIFRMTPFHHHLELG
GLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILYVF
>M28_Spy0413 glycosyltransferase
MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQHFTTNPRETYDLVHLN
TYGLKSWLLMIKAQKAGKKVIMHGHSTEEDFRNSFIFSNLLSPWFKKYLC
HFYNKADAIITPTLYSKSLIESYGVKSPIFAVSNGIDLEQYGADSKKEAA
FRRYFDIKEGEKVVMGAGLFFLRKGIDDFVKVAQAMPDVRFIWFGETNKW
VIPAQVRQMVNGNHPKNLIFPGYIKGDVYEGAMTGADAFFFPSREETEGI
VVLEALASRQHLVLRDIPVYYGWVDQSSAELATDIPGFIEALKKVFSGAS
NKVEAGYKVAQSRRLETVGHALVDVYKKVMEL
>M28_Spy0242 D-alanyl-D-alanine carboxypeptidase
MTKRIILTIFTFICFSVMPLVQAEDVMDITRQAGYTVSEVNRPKSSIVVD
ANSSDILWQDNIDIPRDPASMSKMFTLYILFEELAKGKITMDTTITATPT
DQAIANIYEISNNNIVAGVAYPIRDLITMTAVPSSNAATVMIANYLSNND
ASAFIDRINATAKQLGMTNTHFSNASGAAAQAFQGYYNPTKYDLSASNIT
TARDLSKLLYAFLKKYPEIISFTNKSVVHTMVGTPYEEEFHTYNHSLPDN
QFGMKGVDGLKTGSSPSAAFNAMITAKRGKTRLITIVMGVGDWSDQNGEF
YRHPFVNALTEKGFKDSKTLSKKARQKLEKLVPQTKKETSPKQQHFKATK
KQSYLERVEDFMNHNHTFLLICLAIFIITILLLSLVVFAMGRQ
>M28_Spy1458 phosphotransferase enzyme family
MTTTEQELTLTPLRGKSGKAYKGTYPNGECVFIKLNTTPILPALAKEQIA
PQLLWAKRMGNGDMMSAQEWLNGRTLTKEDMNSKQIIHILLRLHKSKKLV
NQLLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFKS
EVATIVHGDIKHSNWVITTSGMIFLVDWDSVRLTDRMYDVAYLLSHYIPR
SRWSEWLSYYGYKNNDKVMQKIIWYGQFSHLTQILKCFDKRDMEHVNQEI
YALRKFREIFRKK
>M28_Spy1662 pheromone-processing membrane metalloprotease
MLGIITFIIIFGILVIVHEFGHFYFAKKSGILVREFAIGMGPKIFSHVDQ
GGTLYTLRMLPLGGYVRMAGWGDDKTEIKTGTPASLTLNEQGFVKRINLS
QSKLDPTSLPMHVTGYDLEDQLSITGLVLDETKTYKVAHDATIVEEDGTE
IRIAPLDVQYQNASIGGRLITNFAGPMNNFILGIVVFILLVFLQGGMSDF
SSNHVRVQENGAAAKAGLRDNDQIVAINGYKVTSWNDLTEAVDLATRDLG
PSQTIKVTYKSHQRLKTVAVKPQKHAKTYTIGVKASLKTGFKDKLLGGLE
LAWSGAFTILNALKGLITGFSLNKLGGPVAMYDMSNQAAQNGLESVLSLM
AMLSINLGIFNLIPIPALDGGKILMNIIEAIRRKPIKQETEAYITLAGVA
IMVVLMIAVTWNDIMRVFF
>M28_Spy0975 phage protein
MSRDPTLLIDESNLTIGSDGRAYYTFTADGDTKSVKIANNKCIGTTRFNQ
LMIERGGKPTNYVAPVVVEGTGNPTGLFKDLKEISLELTDTKNSKLWSKI
KLNNQGMIEEYYNGTIKSEIIKTAEGTQQRISSETDKKLALINETVSGIR
REYQDADRQLSSSYQAGIEGLKATMANDKIGLQAEIQTTAQGLYQRYDNE
IRKLSAKITTTSSGTTEAYESKLDGLRAEFTHSNQGMRVELESKISGLQS
TQQATARQISQEISNREGAVSRVQQGLDSYQRRLQNAEGSYSSLQQTVSG
LQSDVNSPNSKLNSRISQLASQIDQRVTRADVTSIINQSGDSIKLAIQRA
GGIDAKMSAKEIVSAINLNGYGVRISGERIALDGNTTVNGAFGAKIGEFI
KLKADQIIGGTIDANKINVINLNASSIVGLDANFIKARIEYAITSLLEGK
VIKARNGAMTIDLQSGQINHYTNESAMRRIDSSTASQFIKMTKSGFISEI
GNMQAAMTVIGSNSDGSENHENKTFGGIRIWNGKSSYQSTSFVELVGNRV
AIYGNKNRSPWLFDSTTSGYAYLIPQNESGIKHAIGRADRKIDQIHVGDI
YVQGERVAMMLKDLANRIGYIGTGGWANRIG
>M28_Spy1712 periplasmic component of efflux system
MFQLRKKMTRKQLALLSAGVLTCVVGGSYLIMNHQQQEIVSSVNKVKALT
IKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKDVFVKKGDVVKVG
QPLFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEIN
TLKSRYNTAPDESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKAN
ATATTEKGKLEYDTVKSDTAGTIVSLNTDLPNQSKSKKENETFMEIIDKS
KMLVKGNISEFDRDKLKIGQKVEVIDRKDNSKKWTGKVTQVGNLKAEEKG
QGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLIGSHTYVNVLNNVPEAG
KIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVEVTSGLTMQ
DKIAQPLPGMKDGMEVGSIVKP
>M28_Spy1325 putative cell surface protein
MKQMETKGYGYFRKTKAYGLVCGITLAGALTLGTTSVSADDVTTLNPATN
LTTLQTPPTADQTQLAHQAGQQSGELVSEVSNTEWDNAVTTAQKAGVTVK
QSEKVTHDSLSSAQADLEKQTQAVTEATTKQEANTTAINQAVSENKAIDQ
ANRDEKARVDALNTKGEADTKAKNETGQAQVDAQNKQAQAAADAMNAKLK
ADYEAKLTEIKQIESENEAIRQRNQQASQATHQANQAAQAAYQEKLAEIE
RIKAENAAIRDRNAKAQQEAERQNQALQAAYEAKLAEIKQIESENAAIRQ
RNEQAGQATNQTNQAAQAAYQEKLAEIERIKAGNAAIRDRNAKAQQEAER
QNQALQAAYEAKLAEIKQIESENAAIRKRNEQAGQTTNQTNQAAQAAYQE
KLAEIERINAENAAIRDRNTKARQEAERQNQQLKTTYEAQLSAYQQALQA
KKEAENKAIDQVVFGIDAKANGVDNAEYGNSIMTVTTQPDGSFVFKHDMI
DGVKTIGHGTLTGKINHHYEANKDGSITAYIDSVTFDKYEYQNVAKNDAV
DKNIAFRILSATGQELFVKAHDGDKTFSETLNKTVSLKLTYQLKPHEAVK
DIKVFQLHDDWVHDTHGSALVSYVNNNDAVPHIEVPEKPVEPDMVTPKVE
QEKPVPEAPQKPTDGVPNLEKEKPVPPTPVKPEAVKPVLEQEKPVPEAPQ
KPTDDVPNLEKEKPVPPTPVKPEAVKPVLEQEKPVPEAPQKPTDDVPNLE
KEKPVPPTPVEPEAIKPDLQSFTPEVYDPIKPVVKPHVTVPEKVVYEVMV
HPVQVKQTPTNVKSVTNSDQVNIDGQLVPKGSTVTWELVNTSLKAGRQDI
TSYELTDPLPDGFELDVTATQTLSPEWVITTDEAGKVSLKASQSLLAHFN
AKRDQDVEVPKVSLVGRLLNDAGTYHNTFKTVVTTPTGSYTVISNTPVIY
TPGNDPKTPRNPGGDNPTPHDNLIQPTKTIVDDKGQSIDGKSVLPNSTLT
YVAKQDFDQYKGMTAAKESVMKGFIYVDDYKDEAIDGHSLVVNSIKAANG
DDVTNLLEMRHVLSQDTLDDKLKALIKASGISPVGEFYMWVAKDPAAFYK
AYVQKGLDITYNLSFKLKQDFKKGDITNQTYQIDFGNGYYGNIVVNHLSE
LTVHKDVFDKEGGQSINAGTVKVGDEVTYRLEGWVVPTNRGYDLTEYKFV
DQLQHTHDLYQKDKVLATVDITLSDGSVITKGTDLAKYTETVYNKETGHY
ELAFKQDFLAKVVRSSEFGADAFVVVKRIKAGDVANEYTLYVNGNPVKSN
KVTTHTPEQPQPVTPKAPALPSTGEQGVSILTALGAALLSLLGYVGLKKR
QQ
>M28_Spy0235 undecaprenyl-phosphatealpha-N-acetylglucosaminephosphotransferase
MFSFTIDYVLVLIGALLMSLFLTPLVRFLAFRVGAVDNPNARRVNKVPMP
TSGGLAIFMSFLVASLGLIPIASKGAMFFGQTYFSYILPVVIGATVITLT
GFLDDLYELSPKLKMFGILIGAVIVWAFTDFKFDSFKIPFGGPLLVFGPF
LTLFLTVLWIVSITNAINLIDGLDGLVSGVSIISLVTMAIVSYFFLPQKD
FFLTLTILVLISAIAGFFPYNYHPAMIYLGDTGALFIGFMIGVLSLQGLK
NSTAVAVVTPVIILGVPIMDTIVAIIRRSLSGQKFYEPDKMHLHHRLLSM
GFTHRGAVLVVYGITMLFSLISLLLNVSSRIGGVLLMLGLLFGLEVFIEG
LEIWGEKRTPLFNLLKFIGNSDYRQAMLLKWKEKKDLKH
>M28_Spy0370 surface antigen
MIITKKSLFVTSVALSLAPLATAQAQEWTPRSVTQIKSELVLVDNVFTYT
VKYGDTLSTIAEAMGIDVHVLGDINHIANIDLIFPDTILTANYNQHGQAT
TLTVQAPASSPASVSHVPSSEPLPQASATSQSTIPMAPSATPSDVPTTPL
ASAKPDSFVTASSELTSSTNDVSTELSSESQKQPEVPQEAVPTPKAAETT
EVEPKTDISEDSTSANRPVPNESASEEASSAAPAQAPAEKEETSQMLTAP
AAQKAVADTTSVATSNGLSYAPNHAYNPMNAGLQPQTAAFKEEVASAFGI
TSFSGYRPGDPGDHGKGLAIDFMVPVSSTLGDQVAQYAIDHMAERGISYV
IWKQRFYAPFASIYGPAYTWNPMPDRGSITENHYDHVHVSFNA
>M28_Spy1053 DltB
MMMFFSHIPYMEPYGNPIYFVYLILAFLPVIIGIFKQKRLSTYETLVSLV
FILFMFGGDHYQQLVAFLFYLLWQIISVFAYQKYREKANSAGVFYLAIAM
ALFPLIWVKVAPLTGPSSQTLFSFLGISYLTFKSIGMIIEMRDGTLQEVR
LPDFIRFMIFFPTFSSGPIDRFRRFQEDYHKLPERDDYFAMLNKAVMYLM
LGFLYKHIISYCLGGILLPLLENKALMVGGYFNKETILVMYVYGLNLFFD
FAGYSMFAIGISYLLGIRTPENFNMPFLSASLKDFWNRWHMSLSFWFRDY
VFMRLVHLLIKHKTFKNRNVTSGVAYLVNMLVMGFWHGLTWYYIAYGLFH
GIGLIINDAWIRKKKEINRHRKKKGLSPLFQSRAFHVLCIVVTFHVVMFS
LLLFSGFLNDLWFNRPLH
>M28_Spy1154 penicillin-binding protein
MANPNGSVTIHAKIGTAETCITDNSDQTLVTYNLNVVAYNTNNEDNIAVA
VMYPHITNISAKM
>M28_Spy1326 putative cell surface protein
MKQTKVLTGIAVAALSTGTGLVQADDLSNTRPAKAAEVVTHTEVTENQVA
DAKTKADEATKAVKDQEATVKAIEAEKSQAQQSLVEATTAVNDTEKLASE
ATPDGLTKAQEETEASQSAVTDAQAQLEAAQEAESKAQTAVDHQKETVAK
ASQAVNQAKAALTTSNQAADVSAAEEKVLEAQEAVTKAETQVSQAQEADA
KHESDVRHAKEELDLKSQKLTEKQTTLEQVMAAIEAERLTKPVENGTYFN
QRDNEWQKAYGGKTFAATGCVPSALAMVFSELAKREVTPTEIADYLWHNT
DEFNKHYGGTSGKGLVAATNHYGFASTHLDSQSTIIAALQAGHHVLAAVQ
NNKFSPWGSQYSHEIVLRGYSNGNTYVYDPYNRANIGWYPIANLWNEQSR
DAIDTAEVGVPFFKITTQKMAQLEMAKAVANEGLDEAKQAVKQAEANVTA
LEQVISQTSQAKEQLAAAKANLVTAKDMLDKAKQTAKLTEQDLETKTANL
KQAQEHLTLKQDDLAKAQTELAAQEKSLEQLTQVLSLAQENLGRATKAVE
QTKADLTQKQAYVTNLKQVTKLRQESQAKVNQAKAVLSEASARLEQELET
LKTLQAKEANLTAQYQAIFKAYQAVLAVKHHSQLAESKAKLEAKGEEAVP
VVNEVGHVTDYVSGPTQLADAVAVRTEETSSKTKNTSPVSVKLMAKQGHQ
KALETIVTSQSSLPQTGEQVVSILSLVGLNFLGLSSFLGLRKQEEK
>M28_Spy0588 phosphoglycerol transferase
MIKDTFLKTNWLNISHHIILLVFGFYFSFYSLAKELVSSTAQPVNYYAHL
LNVSFVGYIISLIGLSYYLSRQVSRQLFLKTSFIVISYLIVSYWVQITQH
LNDKRFDIWSLTKNQFYQFQALPSLLIILVMATLIKILVAYFAIEKDRFG
LLGYQGNTFSVALILAVVPINDIHLLKLISSRFSELVRAGNSQIALLKIS
GLLIVLLVIFATIIYVVLNALKHLKSNKPSFSVAATTSLFLALVFNYTFQ
YGVKGDEALLGYYVFPGATLFQIVAITLVALLAYVITNRYWPTTFFLLIL
GTIISVVNDLKESMRSEPLLVTDFVWLQELGLVTSFVKKSVIVEMVVGLA
ICIVVAWYLHGRVLAGKLFMSPVKRASAVLGLFIVSCSMLIPFSYEKEGK
ILSGLPIISALNNDNDINWLGFSTNARYKSLAYVWTRQVTKKIMEKPTNY
SQETIASIAQKYQKLAEDINKDRKNNIADQTVIYLLSESLSDPDRVSNVT
VSHDVLPNIKAIKNSTTAGLMQSDSYGGGTANMEFQTLTSLPFYNFSSSV
SVLYSEVFPKMAKPHTISEFYQGKNRIAMHPASANNFNRKTVYSNLGFSK
FLALSGSKDKFKNIENVGLLTSDKTVYNNILSLINPSESQFFSVITMQNH
IPWSSDYPEEIVAEGKNFTEEENHNLTSYARLLSFTDKETRAFLEKLTQI
NKPITVVFYGDHLPGLYPDSAFNKHIENKYLTDYFIWSNGTNEKKNHPLI
NSSDFTAALFEHTDSKVSPYYALLTEVLNKASVDKSPDSPEVKAIQNDLK
NIQYDVTIGKGYLLKHKTFFKISR
>M28_Spy0589 glycosyltransferase involved in cell wall biogenesis
MKKLIIIPAYNESSNIVNTIRTIESDAPDFDYIIIDDCSTDNTLAICQKQ
GFNVISLPINLGIGGAVQTGYRYAQRCGYDVAVQVDGDGQHNPCYLEKMV
EVLVQSSVNMVIGSRFITKEGFQSSFARRIGIKYFTWLIALLTGKKITDA
TSGLRLIDRSLIERFANHYPDDYPEPETVVDVLVSHFKVKEIPVVMNERQ
GGVSSISLTKSVYYMIKVTLAILVVRLKGNR
>M28_Spy1491 D-alanyl-D-alanine carboxypeptidase
MKHNHFKLLLQTLVVLLFVGGIYLFIKPEKQATKTPSSQQASSQKVVKNS
KESTGLPKVSPKDWELILVNRDHMTEELSPELVDINGISVDKRIEQATSD
FLAAAQAIDPQEHLISGYRSVAYQAELYQSYIKKEMANDPTLTQEAAEAL
VQTYLQPPGASEHHTGLAIDMSTVDTLNASDPSVSKAVQKIAPDYGFVLR
FPEGKKTSTGVDYEDWHYRYVGKASARYMAQHNLTLEEYIAALKEKR
>M28_Spy0479 N-acetylmuramoyl-L-alanine amidase
MRRKIKPIVVLVFFILLAMVLIIGKRQANHAKQKEVEDAKSHIPIATSNP
SKAKTSTSETEDFILNPIVDVSGWQLPEEIDYDTLSRHISGAIVRVYGGS
QITAHNNAAFTTGIDKSFKTHIKEFQKRNVPVAVYSYALGRSTKEMKEEA
RAFYKNAAPYNPTYYWIDVEEATMKDMNKGVTAFREELKKLGAENVGLYI
GTYFMAEQDISTKGFDAVWIPTYGSDSGYYEAAPNTTLDYDLHQYTSQGY
LSGFNNALDLNQIAVTKDTKKTFEKLFGNSNN
>M28_Spy0625 periplasmic component of efflux system
MSKRGKIKITTKTKLITASVITLVLIITGVVLWKQQQNTLTADIAKEPYS
TVSVTEGSIASSTLLSGTVKALSEEYIYFDANKGNDATVTVKVGDQVTQG
QQLVQYNTTTAQSAYDTAVRSLNKIGRQINHLKTYGVPAVSTETNKDEAT
GEETTTTVQPSAQQNANYKQQLQDLNDAYADAQAEVNKAQIALNDTVVIS
SVSGTVVEVNNDIDPSSKNSQTLVHVATEGQLQVKGTLTEYDLANVKVGQ
SVKIKSKVYSNQEWTGKISYVSNYPTESNAGSTTPAGSTGAGSSTGAAYD
YKIDIISPLNQLKQGFTVSVEVVNEAKQALVPLTAVIKKDKKHYVWTYDD
ATGKAKKVEVTLGNADAQQQEIHKGVAVGDIVIANPDKNIKPDKKLEGVI
SIGTNTKPEKDSQSKNKKSGVDK
>M28_Spy1522 acpS, alanine racemase
MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAYGHGAVQ
VSKALLPQVDGYCVSNLDEALQLRQAGIDKEILILGVLLPNELELAVANA
ITVTIASLDWIALARLEKKECQGLKVHVKVDSGMGRIGLRSSKAVNLLID
SLKELGADVEGIFTHFATADEADDTKFNQQLQFFKKLIAGLEDKPRLVHA
SNSATSIWHSDTIFNAVRLGIVSYGLNPSGSDLSLPFPLQEALSLESSLV
HVKMISAGDTVGYGATYTAKKSEYVGTVPIGYADGWTRNMQGFSVLVDGQ
FCEIIGRVSMDQLTIRLPKAYPLGTKVTLIGSNQQKNISTTDIANYRNTI
NYEVLCLLSDRIPRIY
>M28_Spy0523 agaS, galactosamine-6-phosphate deaminase (isomerizing)
MFTKTQEALEALGAAITTKEIKQEPRLWQETMTFFEETRDSLDSFLKRVC
KSANGNNVHVIFTGAGTSEYIGNTICPYLKKVGNRQCYLFESVASTDLVA
APDYYLAEEETVLLVSFARSGNSPESVAAVNLVNQLVPNSYHLTITCAKD
GELAKKAQQDERSYLYLMPEDANDAGFAMTGSFTCMMLAALLIFDDANSI
AQKEAYVTDMILAGQAVIDQERRLQELADLGFERLVYLGSAGLAKLTQEA
QLKMLELTAGQVATLYESSMGFRHGPKSFINDRTLVIGFVNNDAYVRQYD
LDMLEEIQADGIALKILALLQGGDINFSEDQFRLDTRHLLPEAYLAFPMI
LVAQTLALLTAVTLGNSPDTPSATGTVNRVVKGVTIHPYPTSSRQCNKA
>M28_Spy0612 capA, capsule biosynthesis protein
MILLKSLYKGFFAAMKEENFEARCYNREKGGCVLIKTMQYKKTMATVVAL
IVALLLFGLIYDLLGVQKNKLAAQKSAQPKVKTARVVANGDILIHDILYM
SARKADDTYDFTPYFEYVKDWISGADLAIGDYEGTISPDYPLAGYPLFNA
PEEIAGALKNTGYDVVDLAHNHILDSQLDGALNTKKVFHQLGIDSIGIYD
KDRSKESFLIKNVNGIKIAILGYSYGYNGMEATLSQEDYEKHMSDLDEAK
IKKELQLAEKKADVTIVMPQMGTEYALEPTAEQKELYHKMIDWGADVVLG
GHPHVIEPSETVIKGRQKKFIIYSMGNFISNQRLETVDDIWTERGLLMDL
TFEKKDNKTKIKTVEAHPTMVLAKGKGIVGKEGFELYNYRTMVLEDFIKG
GKYHDKIDEETKAKVALAYQEINDLVNLKW
>M28_Spy0107 cpa, collagen-binding protein
MNNKKLQKKQDAPRVSNRKPKQLTVTLVGVFLMLLVLIGFEGKVRAAHEL
VEVPVPIFHNPDPQSDYQWYGYEAYTGGYPKYDLFKTYYHDLRVNLHGSK
SYQVYCFNVHKHYPRSSQSFDRKWYKKLDGTAENFDSLAMEPRVRKEELT
KKLRAVMYNAYPNDANGIMKDLEPLNAIKVTQEAVWYYSDSAQINPDESF
KTEAQSNGINDQQLGLMRKALKELIDPNLGSKYSNKTPSGYRLNVFESHD
KTFQNLLSAEYVPDTPPKPGEEPPAKTEKTSVIIRKYAEGDYSKLLEGAT
LRLTGEDIPDFQEKVFQSNGTGEKIELSNGTYTLTETSSPDGYKIAEPIK
FRVVNKKVFIVQKDGSQVENPNKEVGSPYTIEAYNDFDEFGLLSTQNYAK
FYYGKNYDGSSQIVYCFNANLKSPPDSEDHGATINPDFTTGDIRYSHIAG
SDLIKYANTARDEDPQLFLKHVKKVIENGYHKKGQAIPYNGLTEAQFRAA
TQLAIYYFTDSVDLTKDRLKDFHGFGDMNDQTLGVAKKIVEYALSDEDSK
LTNLDFFVPNNSKYQSLIGTEYHPDDLVDVIRMEDKKQEVIPVIHSLTVK
KTVVGELGDKTKGFQFELELKDKTGQPIVDALKTNNQDLVAKDGKYSFNL
KHGDTIRIEGLPTGYSYTLKETEAKDYIVTVDNKVSQEAQSASENVTADK
EVTFENRKDLVPPTGFTTDGGTYLWLLLLVPFGLLVWFFGRKGLKND
>M28_Spy0714 cpsFO, glucose-1-phosphate thymidylyltransferase
MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLAGIKDIL
IISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDD
RVALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDE
NMNAISIEEKPEVPKSHFAVTGLYFYDNDVVEIAKNIKPSARGELEITDV
NKAYLERGDLSVELMGRGFAWLDTGTHESLLEAAQYIETVQRLQNAQVAN
LEEIAYRMGYISKEDVHELAQSLKKNEYGQYLLRLIGEA
>M28_Spy0715 cpsFP, dTDP-4-dehydrorhamnose 3,5-epimerase
MTETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEKMLPIGF
PERFFEEGKLQNNVSFSRQHVLRGLHAEPWDKYISVADDGKVLGAWVDLR
EGETFGNVYQTVIDASKGMFVPRGVANGFQVLSETVSYSYLVNDYWALDL
KPKYAFVNYADPSLGITWENLAAAEVSEADKNHPLLSDVKPLKPKDL
>M28_Spy0716 cpsFQ, dTDP-glucose 4,6-dehydratase
MYKNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNRANIEAIL
GDRVELVVGDIADAELVDKLAAKTDAIVHYAAESHNDNSLEDPSPFIHTN
FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGQGEGPGEKFTAE
TKYNPSSPYSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFI
PRQITNILSGIKPKLYGEGKNVRDWIHTNDHSTGVWAILTKGRIGETYLI
GADGEKNNKEVLELILEKMGQPKDAYDHVTDRAGHDLRYAIDSTKLREEL
GWEPQFTNFSEGLEETIKWYTENETWWKAEKDAVEAKYAKTQEVIK
>M28_Spy0794 dacA1, D-alanyl-D-alanine carboxypeptidase
MLLLQGTCFMSLFKLLKVGATILPSKFLRIFAIIVTMKDIMIKRWVILFF
MVLTCSGFGKTVLAADFQVGAEHAIVVEADSGRVLYEKDAKTPDAIASLT
KLVTAYLVLDKVKSGQLQLSDQVNLSDYAFELTKDRSLSNVPFDKKTYSV
QDLLTATLVASSNSAAIALAEKVAGSELHFVNQMREQLSHWGITSGKILN
ASGLPNEVLKDNRYPGSALEEENTLSAQDVAVVTMHLLEDFPEILEITKQ
TEVNFAGNSIKSFNQLLPGMAKGRAGVDGLKTGTTDLAGHCLVVTSIENG
MRVITVILNADGSDKNQNTRFEQANRLLDYVDRTYCRRKILKKGSLVLER
SLPIQDGQVKELPVSVAEDVTIILQQGEQVPKPKQFMISETSLLAPITKG
EVVAYLTSPRITDQSVRYLKEPKRIPLKASQSLKKASDLQLWWRDFLEKR
R
>M28_Spy0243 dacA2, D-alanyl-D-alanine carboxypeptidase
MIKRLISLVVIALFFAASTVSGEEYSVTAKHAIAVDLESGKVLYEKDTKE
VVPVASVSKLLTTYLVYKEVSKGKLNWDSPVTISNYPYELTTNYTISNVP
LDKRKYTVKELLSALVVNNANSPAIALAEKIGGTEPKFVDKMKKQLRQWG
ISDAKVVNSTGLTNHFLGANTYPNTEPDDENCFCATDLAIIARHLLLEFP
EVLKLSSKSSTIFDGQTIYSYNYMLKGMPCYREGVDGLFVGYSKKAGASF
VATSVENQMRVITVVLNADQSHEDDLAIFKTTNQLLQYLLINFQKVQLIE
NNKPVKTLSVLDSPEKTVKLVAQNSLFFIKPIHTKTKNTVHITKKSSTMI
APLSKGQVLGRATLQDKHLIGQGYLDTPPSINLILQKNISKSFFLKVWWN
RFVRYVNTSL
>M28_Spy1152 ddlA, D-alanine--D-alanine ligase
MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFITQMGQFI
KTQQFSEKPSESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGED
GSIQGFLEVLRMPYIGTNVMSSSIAMDKITTKRVLESIGIPQVAYTVYID
GQDLEACLVETLARLTFPIFVKPANMGSSVGISKAQTKVELRKAIQLALT
YDSRVLIEQGVVAREIEVGLLGNDKVKSTLPGEVIKDVDFYDYQAKYVDN
KITMAIPADVDQSIVTEMRSYAEVAFKALGGCGLSRCDFFLTQDGQVYLN
ELNTMPGFTQWSMYPLLWENMGLAYPDLIEELVTLAQEMFDQRESHLI
>M28_Spy0375 dgk, diacylglycerol kinase
MALHDNNTTKRKWKNRTITSSLEFALTGVFTAFKEERNLRSHLLSACLAC
VAGLFFSISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAK
NAKDMAAGAVLMISGYAVLTGLIIFIPKIWNIFVH
>M28_Spy1190 divIB, cell division protein
MAKDKEKQSDDKLVLTEWQKRNIEFLKKKKQQAEEEKKLKEKLLSDKKAQ
QQAQNASEAVELKTDEKTDSQEIESETTSKPKKPKKVRQPKEKSATQIAF
QKSLPVLLGALLLMAVSIFMITPYSKKKEFSVRGNHQTNLDELIKASKVK
ASDYWLTLLTSPGQYERPILRTIPWVKSVHLSYQFPNHFLFNVIEFEIIA
YAQVENGFQPILENGKRVDKVRASELPKSFLILNLKDEKAIQQLVKQLTT
LPKKLVKNIKSVSLANSKTTADLLLIEMYDGNVVRVPQSQLTLKLPYYQK
LKKNLENDSIVDMEVGIYTTTQEIENQPEVPLTPEQNAADKEGDKPGEHQ
EQTDNDSETPANQSSPQQAPPSPETVLEQAHG
>M28_Spy1051 dltD, protein precursor
MLKRLWLILGPLLIAFVLVVITIFSFPTQLDHSIAQEKANAVAITDSSFK
NGLIKRQALSDETCRFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIG
KRGSASLSHYYGMQQITNEMQKKKAIFVVSPQWFTAQGINPSAVQMYLSN
TQVIEFLLKARTDKESQFAAKRLLELNPGVSKSNLLKKVSKGKSLSRLDR
AILKCQHQVALREESLFSFLGKSTNYEKRILPRVKGLPKVFSYKQLNALA
TKRGQLATTNNRFGIKNTFYRKRIAPKYNLYKNFQVNYSYLASPEYNDFQ
LLLSEFAKRKTDVLFVITPVNKAWADYTGLNQDKYQAAVRKIKFQLKSQG
FHRIADFSKDGGESYFMQDTIHLGWNGWLAFDKKVQPFLETKQPVPNYKM
NPYFYSKIWANRKDLQ
>M28_Spy0351 gcaD, glucosamine-1-phosphate acetyltransferase
MTNYAIILAAGKGTRMTSDLPKVLHKVSGLTMLEHVFRSVKAISPEKSVT
VIGHKSEMVRAVLADQSAFVHQTEQLGTGHAVMMAETQLEGLEGHTLVIA
GDTPLITGESLKSLIDFHVNHKNVATILTATAQDPFGYGRIVRNKDGEVI
KIVEQKDANEYEQQLKEINTGTYVFDNKRLFEALKCITTNNAQGEYYLTD
VVTIFRANKEKVGAYILRDFNESLGVNDRVALATAETVMRQRITQKHMVN
GVTFQNPETVYIESDVEIAPDVLIEGNVTLKGRTHIGSGTVLTNGTYIVD
SEIGDNCVVTNSMIESSVLAAGVTVGPYAHLRPGTTLDREVHIGNFVEVK
GSHIGEKTKAGHLTYIGNAQVGSSVNVGAGTITVNYDGQNKYETVIGDHA
FIGSNSTLIAPLEVGDHALTAAGSTISKTVPIDSIAIGRSRQVTKEGYAK
RLAHHPSRSK
>M28_Spy0270 gidB, glucose inhibited division protein B
MTPQDFYRTLEEDGFSLSSKQKEQFDTYFKLLVEWNTKINLTAITEENEV
YLKHFYDSIAPILQGFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTII
DSLNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDVVTARAV
ARMQVLSELTIPFLKIGGKLIALKAQAADQELEEAKNALCLLFGKVIKNH
SYQLPNGDSRFITIVEKKKETPNKYPRKAGLPNKKPL
>M28_Spy0958 glmS, isomerizing glucosamine--fructose-6-phosphate aminotransferase
MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNLIKSVGR
IADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNG
VIENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKAL
SIIEGSYAFALMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRE
TSEFMEIHDKELVILTKDKVTVTDYDGKELIRDSYTAELDLSDIGKGTYP
FYMLKEIDEQPTVMRQLISTYADETGNVQVDPAIITSIQEADRLYILAAG
TSYHAGFATKNMLEQLTDTPVELGVASEWGYHMPLLSKKPMFILLSQSGE
TADSRQVLVKANAMGIPSLTVTNVPGSTLSREATYTMLIHAGPEIAVAST
KAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKD
LVAEKVQALLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGE
LKHGTISLIEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEG
LDREGDDIIVNKVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKA
VTVE
>M28_Spy0292 glr, glutamate racemase
MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGPRPKKQI
KEYTWELVNFLLTQNVKMIVFACNTATAVAWEEVKAALDIPVLGVVLPGA
SAAIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSVQVRSLACPKFVPI
VESNEMCSSIAKKIVYDSLSPLVGKIDTLVLGCTHYPLLRPIIQNVMGPS
VKLIDSGAECVRDISVLLNYFDINGNYHQKAVKHRFFTTANPEIFQEIAS
IWLKQKINVEHVTL
>M28_Spy1884 hasA, hyaluronan synthase
MLAQTYPLSEIYIVDDGSSNTDAIQLIEEYVNREVDICRNVIVHRSLVNK
GKRHAQAWAFERSDADVFLTVDSDTYIYPNALEELLKSFNDKTVYAATGH
LNARNRQTNLLTRLTDIRYDNAFGVERAAQSLTGNILVCSGPLSIYRREV
IIPNLERYKNQTFLGLPVSIGDDRCLTNYAIDLGRTVYQSTARCDTDVPF
QLKSYLKQQNRWNKSFFRESIISVKKILSNPIVALWTIFEVVMFMMLIVA
IGNLLFNQAIQLDLIKLFAFLSIIFIVALCRNVHYMVKHPASFLLSPLYG
ILHLFVLQPLKLYSLCTIKNTEWGTRKKVTIFK
>M28_Spy1885 hasB, UDP-glucose 6-dehydrogenase
MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSPIQDEYI
EDYLKSKQLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETV
IKEVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALY
DNLYPSRIIVSCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEA
EAVKLFDNTYLALRVAYFNELDTYAESRKLNSHMIIQGISHDDRIGMHYN
NPSFGYGGYCLPKDTKQLLANYNNIPQTLIEAIVSSNNVRKSYIAKQIIN
VLEERESPVKVVGVYRLIMKSNSDNFRESAIKDVIDILKSKDIKIIIYEP
MLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNKVYSRDIFN
RD
>M28_Spy1886 hasC, UTP-glucose-1-phosphate uridylyltransferase
MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGI
EEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKNELLKLVDETTAINLHF
IRQSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLME
DYDKTHASTIAVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPED
APSDLAIIGRYLLTPEIFDILERQTPGAGNEVQLTDAIDTLNKTQRVFAR
EFKGNRYDVGDKFGFMKTSIDYALEHPEVKEDLKNYIIKLGKALEKSKVP
THSK
>M28_Spy0187 hasC.2, UTP-glucose-1-phosphate uridylyltransferase
MLMTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKS
GIEEILIVTGKSKRSIEDHFDSNFELEYNLQAKGKIELLKLVDETTSINL
HFIRQSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQL
IDDYEETHAATIAVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQP
QDAPSDLAIIGRYLLTPEIFSILEKQEPGAGNEVQLTDAIDTLNKTQRVF
AREFKGKRYDVGDKFGFMKTSLDYALKHPQVKDDLKAYIIQLGKALEKTK
P
>M28_Spy1707 isp, immunogenic secreted protein
MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNNTSSTDQPTTADTDTDDE
SETAKKDKKSKETASQHETQKDHKSSHTHLTPPSNDTKQTDQASSEATDK
PNKDKNDTKQPDSSDQSTPSPKDQSSQKESQNKDGRPTPSPDQQKDQTPD
KTPEKSADKTPEKGPEKATDKTPEPNRDAPKPIQPPLAAAPVFAPWRESD
KDLSKLKPSSRSSAAYVRHWTGDSAYTHNLLSRRYGITAEQLDGFLNSLG
IHYDKERLNGKRLLEWEKLTGLDVRAIVAIAMAESSLGTQGVAKEKGANM
FGYGAFDFNPNNAKKYSDEVAIRHMVEDTIIANKNQTFERQDLKAKKWSL
GQLDTLIDGGVYFTDTSGSGQRRADIMIKLDQWIDDHGSTPEIPEHLKIT
SGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVDR
YMGNGGDWQRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKE
DGSILISESNVMGLGTISYRTFTAEQARLLTYVVGDKLPRP
>M28_Spy0466 lgt, prolipoprotein diacylglyceryl transferase
MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSDAIFDFI
LIAFPLAIVGARIYYVIFEWSYYVKHLDEIIAIWNGGIAIYGGLITGALV
LLAYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNY
LPSFIQKQMFIEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIF
AFYLIWYGSGRLVIEGMRTDSLMFLGIRISQYVSALLIIIGLIFVIKRRR
QKGISYYQE
>M28_Spy0617 lsp, lipoprotein signal peptidase
MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLTYLQNNG
AAFSILQDQQWFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGI
GNFIDRLRLAYVIDMVHLDFVDFAIFNVADSYLTVGVILLVICLWKEEDY
GN
>M28_Spy1410 mraW, S-adenosyl-methyltransferase
MKSFSLTFSFLNLLKYGTIKVMTKEFHHVTVLLHETVDMLDIKPDGIYVD
ATLGGSGHSAYLLSKLGEEGHLYCFDQDQKAIDNAQVTLKSYIDKGQVTF
IKDNFRHLKARLTALGVDEIDGILYDLGVSSPQLDERERGFSYKQDAPLD
MRMDRQSLLTAYEVVNTYPFNDLVKIFFKYGEDKFSKQIARKIEQARAIK
PIETTTELAELIKAAKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESI
QDAMELLALDGRISVITFHSLEDRLTKQLFKEASTVDVPKGLPLIPEDMK
PKFELVSRKPILPSHSELTANKRAHSAKLRVAKKIRK
>M28_Spy0577 mscL, large-conductance mechanosensitive channel
MVKELKAFLFRGNIIELAVAVIIGGAFGAIVTSFVNDIITPLILNPALKA
ANVENITQLSWNGVKYGSFLGAVINFLIIGTSLFFVVKAAEKAMPKKEKE
AAAPTQEELLTEIRDLLAQK
>M28_Spy0562 murA, UDP-N-acetylglucosamine1-carboxyvinyltransferase
MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILRNVPILS
DVFTMNNVVRGLDIRVDFNEAANEITVDASGHILDEAPYEYVSQMRASIV
VLGPILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITA
QADRLQGAMIYMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLAQ
FLNKMGARIRGAGTETLTITGVTSLHGVEHDVVQDRIEAGTFMVAAAMTS
GNVLIRDAVWEHNRPLISKLMEMGVSVTEEEYGIRVQANTPKLKPVTVKT
LPHPGFPTDMQAQFTALMAVVNGESTMVETVFENRFQHLEEMRRMGLQSE
ILRETAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTIVNNLVHLD
RGYYQFHEKLAKLGATISRSSEV
>M28_Spy0802 murB, UDP-N-acetylenolpyruvoylglucosamine reductase
MITELHGIDIRENEPLKHYTYTKVGGPADFLAFPRNHYELSRIVAYANKE
NMPWLVLGNASNLIVRDGGIRGFVIMFDKLNAVHLNGYTLEAEAGANLIE
TTKIAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEISHIFLSAKVLTS
SGEIKTISARDMAFGYRHSAIQETGDIVISAKFALKPGNYDTISQEMNRL
NHLRQLKQPLEFPSCGSVFKRPPGHFAGQLIMEANLKGHRIGGVEVSEKH
AGFMINVVDGTAKDYEDLIAYVIETVENHSGVRLEPEVRIIGENL
>M28_Spy0282 murC, UDP-N-acetylmuramate--alanine ligase
MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGLEQAGIT
ILPFSEDNITPDMELIVGNAFRENNKEVAYALRHQIPFKRYHDFLGDFMK
SFISFAVAGAHGKTSTTGLLSHVLKNITDTSYLIGDGTGRGSANAQYFVF
ESDEYERHFMPYHPEYSIITNIDFDHPDYFTGIADVRNAFNDYAKQVKKA
LFVYGEDDELKKIEAPAPIYYYGFEEGNDFIAYDITRTTNGSDFKVKHQG
EVIGQFHVPAYGKHNILNATAVIANLFVAGIDTALVADHLKTFSGVKRRF
TEKIINDTIIIDDFAHHPTEIVATIDAARQKYPSKEIVAIFQPHTFTRTI
ALLEDFACALNEADSVYLAQIYGSAREVDKGEVKVEDLAAKIIKPSQVVT
VENVSPLLDHDNAVYVFMGAGDIQLYEHSFEELLANLTKNNQ
>M28_Spy1192 murD, UDP-N-acetylmuramoylalanine--D-glutamateligase
MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFDQNPAAQ
ALLEEGIKVICGSHPVELLDEDFEYMVKNPGIPYDNPMVKRALAKEIPIL
TEVELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYP
ASKVVQKAIAGDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSF
EDYVAAKWMIQAQMTESDYLILNANQEISATLAKTTKATVIPFSTQKVVD
GAYLKDGILYFKEQAIIAATDLGVPGSHNIENALATIAVAKLSGIADDII
AQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNILATQKALSGFDNSRLI
LIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKAEVSYLEAR
NVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRG
DA
>M28_Spy0314 murE, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--lysineligase
MITIEQLLDILKKDHNFREVLDADGYHYHYQGFSFERLSYDSRQVDGKTL
FFAKGATFKADYLKEAITNGLQLYISEVDYELGIPVVLVTDIKKAMSLIA
MVFYGNPQEKLKLLAFTGTKGKTTAAYFAYHMLKESYKPAMFSTMNTTLD
GKTFFKSQLTTPESLDLFAMMAECVTNGMTHLIMEVSSQAYLVDRVYGLT
FDVGVFLNISPDHIGPIEHPTFEDYFYHKRLLMENSRAVVINSGMDHFSF
LADQVADQEHVFYGPLSDNQITTSQAFSFEAKGQLAGHYDIQLIGHFNQE
NAMAAGLACLRLGASLADIQKGIAKTRVPGRMEVLTMTNHAKVFVDYAHN
GDSLEKLLSVVEEHQTGKLMLILGAPGNKGESRRADFGRVIHQHPNLTVI
LTADDPNFEDPEDISKEIASHIARPVEIISDREQAIQKAMSLCQGAKDAV
IIAGKGADAYQIVKGQQVAYAGDLAIARHYL
>M28_Spy1151 murF, UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-- D- alanyl-D-alanine ligase
MKLTLHEVAKIVDAQNNVSDLDDVPLHHIEFDSRKITKGDLFLPLKGQRD
GHEFIDLAFQNGAVATFSEKELPGKPHLLVEDCLKAFQKLAHYYIDKMRV
DVIAVTGSNGKTSTKDMIGAVLSTTYKTYKTQGNYNNEIGLPYTVLHMPD
DTEKIVLEMGQDHMGDIRLLSEIARPRIAVLTLVGEAHLEYFGSRDKIAQ
GKMQIVDGMNSDGILIAPGDPIIDPYLPENQMVIRFGNQQEIDVTGIQED
KDSLTFTTNVLATPVSLPLPGKYNATNAMVAAYVGKLLAVTDEDIIAALQ
TVTLTGNRTEWKKAANGADILSDVYNANPTAMRLILETFANIAKNPGGKK
IAVLADMKELGKDSVILHSQLIDSLTSGNIDQLVFYGDHIKELARLASQV
YPAEQVHYFLKTEQEDQFEAMAQYVQNILNPFDQILLKGSHSMSLEKLVD
RLVTDKNCDSYQP
>M28_Spy1191 murG, UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
MFKRRCLMPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIE
HTEIEKSGLDVTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKL
RPQALFSKGGFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTM
YTTFEQEDQLSKVKHLGAVTKVFKDANQMPESTQLEAVKEYFSRDLKTLL
FIGGSAGAHVFNQFISDHPELKQRYNIINITGDPHLNELSSHLYRVDYVT
DLYQPLMAMADLVVTRGGSNTLFELLAMAKLHLIVPLGKEASRGDQLENA
TYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATMLATKEIQSPD
FFYDLLRADISSAIKEK
>M28_Spy1099 murZ, UDP-N-acetylglucosamine1-carboxyvinyltransferase
MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDV
DSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGS
LLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNG
QKIHGAHIYMDTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLL
NNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTYIALAAAIGKG
VKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPY
PGFATDLQQPLTPLLLKADGRGTIIDTIYEKRINHVPELMRMGADISVIG
GQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITNIEFILRGY
ASIIAKLTALGADIQLIED
>M28_Spy0211 nanH, N-acetylneuraminate lyase
MTDLTKYQGIIPAFYACYDDQGAISPERVRALTQYYIDKGVQGLYINGSS
GECIYQSVFDRQLVLENVMAVAKGKLTIINHVACNNTKDSIELAAHSERL
GVDAIAAIPPIYFRLPEYAVADYWNAISSAAPHTDFIIYNIPQLAGVALT
PSLYKTMLANKRVIGVKNSSMPVQDIQTFCAIGGDDHIVFNGPDEQFLGG
RLMGAAAGIGGTYGAMPELFLRLNQLIVDKDLEKAKTLQYTINETIGVLV
SAHGNMYGVIKEVLRINEGLDIGSVRSPLAELVEEDRVICQRAAALINQA
KETF
>M28_Spy1396 pbp1A, multimodular transpeptidase-transglycosylase
MITIKNPKILKWLKYVLSAILSLIILVIIIGGLLFTFYISSAPKLSEAQL
KSTNSSLVYDGNNNLIADLGSEKRENVTADSIPINLVNAITSIEDKRFFN
HRGVDLYRIFGAAFHNLTSQTTQGGSTLDQQLIKLAYFSTNESDQTLKRK
AQEVWLALQMERKYTKQEILTFYINKVYMGNGNYGMLTAAKSYYGKDLKD
LSYAQLALLAGIPQAPSQYDPYLHPEAAQNRRNVVLQQMYMEKHLTKAEY
ETAIATPVAEGLQSLQQRSTYPKYMDNYLKQVIEEVKKETNKDIFTAGLK
VYTNIIPDAQQTLYNIYHSGDYVYYPDQDFQVASTIVDVTNGHVIAQLGG
RNQDENVSFGTNQAVLTDRDWGSTMKPITAYAPAIESGVYTSTAQSTNDS
VYYWPGTTTQLFNWDLRYNGWMTIQAAIMLSRNVPAVRALEAAGLDYARS
FLSSLGINYPEMHYSNAISSNNSSSDKKYGASSEKMAAAYAAFANGGIYH
KPRYVNKVEFSDGTSKTFDEKGKRAMKETTAYMMTDMLKTVLTYGTGTAA
AIPGVAQAGKTGTSNYTDEELAKIGEKYGLYPDYVGTLAPDENFVGFTKR
YAMAVWTGYKNRLTPVYGSSLEIASDVYRSMMTYLTNGYSEDWTMPNGLY
RSGGFLYLSGTYASNTDYTNSVYNNLYSNNTTTASSQTTSDDTSSSNDIS
NSTNTDNNSNHPSTDDKKTTH
>M28_Spy0080 pbp1b, multimodular transpeptidase-transglycosylase PBP 1B
MRYFMVKWNTKQKRISHQRLGLLDLGPVLLRTLRLLSNFFYIVIFLFGMM
GFGMAFGYLASQIESVKVPSKESLVKQVESLTMISQMNYSDNSLISTLDT
DLLRTPVANDAISENIKKAIVSTEDEHFQEHKGVVPKAVFRATLASVLGF
GEASGGSTLTQQLVKQQVLGDDPTFKRKSKEIVYALALERYMSKDNILCD
YLNVSPFGRNNKGQNIAGVEEAARGIFGVSAKDLTVPQAAFLAGLPQSPI
VYSPYLSTGQLKSEKDMAYGIKRQQNVLYNMYRTGVLSKKEYEDYKAYPI
QKDFIQPGSAIVNNHDYLYYTVLADAKKAMYSYLIKRDKVSSRDLKNDET
KAAYEERALTELQQGGYTITTTINKPIYNAMQTAAAQFGGLLDDGTGTVQ
MGNVLTDNATGAVLGFVGGRDYALNQNNHAFNTIRSPGSSIKPIIAYGPA
IDQGLMGSASVLSNYPTTYSSGQKIMHADSEGTAMMPLQEALNTSWNIPA
FWTQKLLREKGVDVENYMTKMGYKIADYSIESLPLGGGIEVSVAQQTNAY
QMLSNNGLYQKQYIVDKITASDGTVVYKHENKPIRIFSAATATILQELLR
GPITSGATTTFKNRLAAINPWLANADWIGKTGTTENYTDVWLVLSTPKVT
LGGWAGHDDNTSLAPLTGYNNNSNYLAYLANAINQADSNVIGVGQRFNLD
PGVIKANVLKSTGLQPGTVNVNGHTFSVGGEMTTSLWSQKGPGAMTYRFA
IGGTDADYQKAWGNFGFRKN
>M28_Spy1739 pbp2A, multimodular transpeptidase-transglycosylase
MRFLELLQKKFFPKAYQEKQFLMHQKTRLTPQHNQKQYSPNANHLDSSAT
KNSEQDPAIALQRSRAYEGSPKSRPAWLQKLEAVLPSPQHPIRRFWRRYH
IGKLLMILIGTLVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDHKGEYA
GSLSGQKGSYVELNAISDDLENAVIATEDRTFYSNSGINLKRFLLAVVTA
GRFGGGSTITQQLAKNAYLSQDQTIKRKAREFFLALELTKKYSKKDILTM
YLNNSYFGNGVWGVEDASQKYFGTTAANLTLDEAATLAGMLKGPEIYNPY
HSLKNATHRRDTVLGAMVDAKKITQTKAQQARAVGLKNRLADTYVGKTDD
YKYPSYFDAVISEAIATYGLSEKDIVNNGYKVYTELDQNYQTGMQTTFNN
DELFPVSAYDGSSAQAASVALDPKTGGVRGLIGRVNSSENPTFRSFNYAT
QAKRSPASTIKPLVVYAPAVASGWSIEKELPNTVQDFDGYQPHNYGNYES
EDVPMYQALANSYNIPAVSTLNDIGIDKAFTYGKTFGLDMSSAKKELGVA
LGGSVTTNPLEMAQAYAAFANNGVIHPAHLINRIENARGEVLKTFTDKAK
RVVSQSVADKMTAMMLGTFSNGTAVNANVYGYTLAGKTGTTETNFNPDLA
GDQWVIGYTPDVVISQWVGFNQTDENHYLTDSSAGTASAIFSTQASYILP
YTKGSQFHVDNAYAQNGISAVYGVNETGNQSGVDTQSIIDGLRKSAQEAS
QSLSKAVDQSGLRDKAQSIWKEIVDYFR
>M28_Spy0113 prtF2, fibronectin binding protein
MTQKNSYKLSFLLSLTGFILGLLLVFIGLSGVSVGHAETRNGANKQGSFE
IKKVDQNNKPLSGATFSLTPKDGKGKPVQTFTSSEEGIIDAQNLQPGTYT
LKEDKAPDGYDKTSRTWTVTVYENGYTKLVENPYNGEIISKAGSKDVSSS
LQLEKSTMSVFSKYGGTEVTSGAADFYRNHAAYFKMSFELKQKDKSETIN
PGDTFVLQLDKRLNPKGISQDIPKIIYDSENSPLAIGKYDAKTHQLTYTF
TNYIAGLDKVQLSAELSLFLENKVVLENQTISDFKSTIGDQEIKYGGTVN
VLYGNASGQDNNYVTNGLSNVGGSIESYNTQTGDFTWYVYVNPNRTNIPY
ATMNLWGFGRLVKSNNSTSKSEDSATSSAQLEKVEIYEVKEDYTLPTSYG
VDLTKLNLRKDLEAKLPQDSTQNSNKRLRIDFGDKLQNKAFVVKITGKTD
QSGKPLVVQSNLASFNNETAVTYGNPVNNVYFQNEIALSPSKGSGSGTSE
FTKPSITVANLKRVAQLRFKKMSTDNVPLPEAAFELRSSNGNSQKVEAKS
NTQGEVHFKDLTSGTYDLYEKQAPKGYQQVTEKLATVTVDTTKPAEEMVT
WGSPHSSVKVEDSKEVTIVNHKETLTFSGKKIWENDRPDQRPAKIQVQLL
QNGQKMSDKVQEVTKDNDWSYHFKDLPKYDDRNQEYKYSVEEVKVPDGYK
VSYLGNDIFNTRETEFVFEQNNFNLEFGNAEIKGQSGSKIIDEDTLTSFK
GKKIWKNDTAENRPQAIQVQLYADGVAVEGQTKFISGSGNEWSFEFKNLK
KYNGTGNDIIYSVREVTVPTGYDVTYSANDIINTKREVITQQGPKLEIEE
TLPLESGASGGTTTVEDSRPVDTLSGLSSEQGQSGDMTIEEDSATHIKFS
KRDIDGKELAGATMELRDSSGKTISTWISDGQVKDFYLMPGKYTFVETAA
PDGYEIATAITFTVNEQGQVTVNGKATKGDAHIVMVDAYKPTKGSGQVID
IEEKLPDEQGHSGSTTEIEDSKSSDLIIGGQGEVVDTTEDTQSGMTGHSG
STTEIEDSKSSDVIIGGQGQVVETTEDTQTGMHGDSGCKTEVEDTKLVQS
FHFDNKESESNSEIPKKDKPKSNTSLPATGEKQHNMFFWMVTSCSLISSV
FVISLKTKKRLSSC
>M28_Spy0582 rgpAc, alpha-(1,2)-rhamnosyltransferase
MQDVFIIGSRGLPAKYGGFETFVEELISHQSSKNIRYHVACLSDTKHKVH
FDYKGADCFYLNPPKLGPARVIAYDMMAITYALSYSDQHQIQNPIFYVLG
NTVGAFIAPFVKQIHNRGGRFFINPDGLEWKRSKWSKPVQAYLKFSEKQM
TRQADLVISDNIGIDRYLKQVYPWSKTCFIAYGTQTQPSRLTTADSKVRA
YFQTFDIREKDYYLILGRFVPENNYETAIKEFMASSTKRDLVIICNHEDN
AYFKQLLAETECDKDPRIKFVGTLYDKELLAYIREQAYAYIHGHEVGGTN
PGLLEALAHTNLNLVLGVDFNQSVAKSAALYWSKQKGQLAELINQVDAGF
DSDRLGKEAKAIIQEHYTWEKIVGEYEALFLNEH
>M28_Spy0583 rgpBc, alpha-L-Rha alpha-1,3-L-rhamnosyltransferase
MNINILLSTYNGERFLAEQIQSIQRQTVNDWTLLIRDDGSTDGTQDIIRT
FVKEDKRIQWINEGQTENLGVIKNFYTLLKHQKADVYFFSDQDDIWLDNK
LEVTLLEAQKHEMTAPLLVYTDLKVVTQHLAICHDSMIKTQSGHANTSLL
QELTENTVTGGTMMITHALAEEWTTCDGLLMHDWYLALLASATGKLVYLD
IPTELYRQHDANVLGARTWSKRMKNWLTPHHLVNKYWWLITSSQKQAQLL
LDLPLKPNDHELVTAYVSLLDMPFTKRLATLKRYGFRKNRIFHTFIFRSL
VVTLFGYRRK
>M28_Spy0584 rgpCc, polysaccharide export ABC transporter permease protein
MNFLTKKNRILLREMVKTDFKLRYQGSAIGYLWSILKPLMMFTIMYLVFI
RFLRLGGNVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFS
KHIIVFSAVLGALINFLINLVVVLIFALINGVTISGYAYLSLFLFIELVV
LVLGIALLLSNVFVYYRDLAQVWEVLLQAGMYATPIIYPITFVLDSHPLA
AKLLMLNPVAQMIQDFRYLLIDRANVTIWQMSTNWFYVVIPYLVPFVILF
IGIFVFKKNADRFAEII
>M28_Spy0585 rgpDc, polysaccharide export ATP-binding protein
MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQHVLKDI
NFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVDGKMVSFIEL
GVGFNPELTGRENVYMNGAMLGFTKDEVDDMYNDIVDFAELHHFMNQKLK
NYSSGMQVRLAFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKDS
GKTTILVTHDMGAVKKYCNRAVLIEDGLVKAYGEPFDVANQYSVDNTETA
EDAMNAEKISVSDIAKDLKVSLISNPRITPNDTITFEVSYEVLKDDFTYI
AFSLTDIDRNIWVYNDNSLDYPTQGIGRKCISYQCQLSQLNDIKLKLEVT
VRDKNGQMLLFSTAEQSPQIVIQRNDIDQDDLSALDSASGLYQRNGKWVF
H
>M28_Spy0586 rgpEc, glycosyltransferase
MYKVSIICTNYNKAPWISDALDSFLSQVTDFEVEIIVIDDASTDDSREIL
KSYQKKSSGKIKLLFNETNIGITKTWIKACLYAKGKYIARCDGDDYWTDS
FKLQKQVDVLEASKRSRWCNTDFDFVNSQGDLLYANAFSSGHTPLTDTYE
KVLALKGMTMASTWLVDADLMRQVNQKINVDTPDDTFDIQLELFQLTQLT
YIKDSTTVYRMTTDSDSRPTDTPKMIHRIQKLLDTQLNYLKKYNQVDTKE
MSELLLQQDAKQEIRIHELSCFIQELQQTIVDKTKQQETREVELQNVIEE
QKNQLSELRQQYHAIINSRQWKYTSKLIAFIRRKK
>M28_Spy0587 rgpFc, alpha-L-Rha alpha-1,2-L-rhamnosyltransferase
MNRILLYVHFNKYNKISAHVYYQLEQMRSLFSKIVFISNSKVSHEDLKRL
KNHCLIDEFLQRKNKGFDFSAWHDGLITMGFDKLEEFDSLTIMNDTCFGP
IWEMGPYFENFEEKEAVDFWGITNNRGTKAFKEHVQSYFMTFKNQVIQNK
VFQQFWQSIIEYENVQEVIQHYETQLTSILLNEGFSYQTVFDTRKAESSF
MPHPDFSYYNPTAILKHHVPFIKVKAIDANQHIAPYLLNLIRETTNYPID
LIVSHMSQISLPDAKYLLSQKYLNCQRLAKQTCQKVAVHLHVFYVDLLDE
FLTAFEDWNFHYDLFITTDSDIKRKEIKEILQRKGKTADIRVTGNRGRDI
YPMLLLKDKLSQYDYIGHFHTKKSKEADFWAGESWRKELIDMLVKPADSI
LSVFETDDIGIIIADIPSFFRFNKIVNAWNEHLIAQEMMSLWRKMDVKKQ
IDFQAMDTFVMSYGTFVWFKYDALKSLFDLELTQNDIPSEPLPQNSILHA
IERLFVYIAWGNSYDFRIVKNPYELTPFIDNKLLNLREDEGAHTYVNFNQ
MGGIKGALKYIIVGPAKAMKYIFLRLMEKLK
>M28_Spy0581 rmlD, dTDP-4-dehydrorhamnose reductase
MLENTKILRKVFYLWQKGELMILITGSNGQLGTELRYLLDERGVDYVAVD
VAEMDITNEDKVEAVFAQVKPTLVYHCAAYTAVDAAEDEGKALNEAINVT
GSENIAKACGKYGATLVYISTDYVFDGNKPVGQEWVETDRPDPKTEYGRT
KRLGELAVERYAEHFYIIRTAWVFGNYGKNFVFAMEQLAENHSRLTVVND
QHGRPTWTRTLAEFMCYLTENQKAFGYYHLSNDAKEDTTWYDFAKEILKD
KAVEVVPVDSSAFPAKAKRPLNSTMNLDKAKATGFVIPTWQEALKAFYQQ
GLKK
>M28_Spy1675 sclA, collagen-like surface protein A
MLTSKHHNLNKLVWRYGLTSAAAVLLAFGGGASSVKAEVSTAAMTKEERQ
QEIEKIKEDIKKEYPKASEEKFWESSFWGRRYFNEQEYLKSLQSFTEQRL
QDIVNLIEKGATKGDKGDAGPKGERGPAGPQGPVGPKGEAGKVGAQGPKG
DPGAPGKDGAKGEKGDKGDTGERGEKGDIGATGAQGPQGEAGKDGAPGEK
GDKGDRGETGAQGPVGPQGEKGETGAQGPAGPQGEAGKPGEQGPAGPQGE
AGKPGEKAPEKSPEGEAGQPGEKAPEKSPEVTPTPETPEQPGEKAPEKSP
EVTPTPETPEQPGEKAPEKSPEVTPTPETPEQPGEKAPEKSPEVTPTPEM
PEQPGEKAPEKSPEVTPTPEMPEQPGEKAPEKSKEVTPAPEKPADKEANQ
TPERRNGNMAKTPVANNHRRLPATGEQANPFFTAAAVAVMTTAGVLAVTK
RKENN