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# Streptococcus pyogenes M1 GAS, SF370

>SPy1035 putative UDP-N-acetylmuramyl tripeptide synthetase
MKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACDKDILKDLSKDYDIVV
VTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKGKS
ERQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQMIV
DGARNAPKATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNTEG
ILCPKCEHILQYRLNTYANLGDFVCLNCQFQRPTLDYQLTELTAITHQSS
EFVIDGQNYKINVGGLYNIYNALAAVSVAEFFGVSPEKIKAGFNKSKAVF
GRQETFTVGDKSCTLILIKNPVGASQALEMIQLADYPFSLSVLLNANYAD
GIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVTGFDDTKIKQA
EKLEQIIETIEKQEAKHAYILATYTAMLEFRSLLADRHVVEKEMI
>SPy1765 putative D,D-carboxypeptidase
MKYNSLNYLVQLLIVIVFLGGLYLFIKPEESVTPTQLNKKEIQQKDIKKT
DRLRALPKVSVEDWELVLVNRDHITKEMSPELADINGISVDKRIEQATSD
FLAAAQAIDLQEHLISGYRSVDYQTELYQSYIKKEMANDPTLTQEAAEAL
VQTYSQPPGASEHHTGLAIDMSTVDTLNASDPSVAKAVQKIAPDYGFVLR
FPEGKKTSTGVDYEDWHYRYVGKASARYMAQHNLTLEEYIAALKEKR
>SPy0515 putative sugar transferase
MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQHFTTNPRETYDLVHLN
TYGLKSWLLMIKAQKAGKKVIMHGHSTEEDFRNSFIFSNLLSPWFKKYLC
HFYNKADAIITPTLYSKSLIESYGVKSPIFAVSNGIDLEQYGADPKKEAA
FRRYFDIKEGEKVVMGAGLFFLRKGIDDFVKVAQAMPDVRFIWFGETNKW
VIPAQVRQMVNGNHPKNLIFPGYIKGDVYEGAMTGADAFFFPSREETEGI
VVLEALASRQHLVLRDIPVYYGWVDQSSAELATDIPGFIEALKKVFSGAS
NKVEAGYKVAQSRRLETVGHALVDVYKKVMEL
>SPy0542 putative nucleotide sugar dehydrogenase
MKITVVGIGYVGLSIGLLLAKEHDVTFFDIDNKKIDLINKRQSPLKEAAI
NKLLCKAKNINATSSEELAYKDATFIILSLPTNLKFNKLDTSIIEISVSN
ILKINKKATIVIKSTVPIGFTEYLRNRFHYNDIIFSPEFLREGSTIHDQL
YPSRTIVGNESRNSQLFLDILTDISVEKDSPSLLVGSSEAEAIKLFSNAY
LAQKIAFFNELDTFAEMQNLDSKKIIEAMGYDQRIGNSHNNPSFGFGGYC
LPKDIKQLEYHFKEIPAPIITSISESNLLRKIHIAKMILNSSAKTIGIYR
INSKKDSDNCRESSTIDVAKLLKSSGKDVIIFEPLINQKKFLGCPLSNDF
NEFIKYSDIIVANRIDDALRKCNSKVFTRDIFQYD
>SPy0540 conserved hypothetical protein
MFVIGIPTLNEADNISRLVKQIDEYAVNLGKEIIIINSDSKSTDGTPQIF
LETKTYNTKVSIVSEAKGKGYNVRNIFEYAINHVPNFSGLILIDGDVVSM
KKMWLEKMFIAIESGNDLIIPNYARKSFEGNATNHFIYPMLVKIFKRDMP
YQCISGDFGFSRGLIKDLTLKCNWHKYTLGYGIDIFLTLTAILKSYKIKE
IDLQSKIHKKSFEKIEKIFLEVSQSFFETINDNSLNQDKLRLNINFESHS
RQFIKSSDILSSNDIENLKLRALFLLQEEKQYLHGLSEVEWDGILSNTIN
NIYRYSSEEHSLYLLPLYLLRVYNYLKYN
>SPy1963 may be involved in production of a peptide sex pheromone
MLGIITFIIIFGILVIVHEFGHFYFAKKSGILVREFAIGMGPKIFSHVDQ
GGTLYTLRMLPLGGYVRMAGWGDDKTEIKTGTPASLTLNEQGFVKRINLS
QSKLDPTSLPMHVTGYDLEDQLSITGLVLEETKTYKVAHDATIVEEDGTE
IRIAPLDVQYQNASIGGRLITNFAGPMNNFILGIVVFILLVFLQGGMPDF
SSNHVRVQENGAAAKAGLRDNDQIVAINGYKVTSWNDLTEAVDLATRDLG
PSQTIKVTYKSHQRLKTVAVKPQKHAKTYTIGVKASLKTGFKDKLLGGLE
LAWSRAFTILNALKGLITGFSLNKLGGPVAMYDMSNQAAQNGLESVLSLM
AMLSINLGIFNLIPIPALDGGKILMNIIEAIRRKPIKQETEAYITLAGVA
IMVVLMIAVTWNDIMRVFF
>SPy0763 putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase
MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILRNVPILS
DVFTMNNVVRGLDIRVDFNEAANEITVDASGHILDEAPYEYVSQMRASIV
VLGPILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITA
QADRLQGAMIYMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLAQ
FLNKMGARIRGAGTETLTITGVTHLRGVEHDVVQDRIEAGTFMVAAAMTS
GNVLIRDAVWEHNRPLISKLMEMGVSVTEEEYGIRVQANTPKLKPVTVKT
LPHPGFPTDMQAQFTALMAVVNGESTMVETVFENRFQHLEEMRRMGLQSE
ILRETAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTIVNNLVHLD
RGYYQFHEKLAKLGATISRSSEV
>SPy1897 conserved hypothetical protein
MTFILHYLEQSHIENIGLTIFKKLVSLIILLLFFAILKRVTNYLFEKTIN
KSFAYSRQSEARKKTLSKLTHNILNYLLYFLLIYWILSLFGIPVSSLLAG
AGIAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDNVTISDIEGSVFGVG
IRTTQIRGFDGTLHFIPNRSITVVSNKSRGNMRALIEIPLYSTVNLSQVT
RIIDEVNQKELPNHPQIVGKPNILGPQNNSNGQFTFRIAIFTENGEQFKI
YHTFYRLYQEALLKEGIQLPTAISYSITSKS
>SPy0469 putative 42 kDa protein
MIITKKSLFVTSVALSLVPLATAQAQEWTPRSVTEIKSELVLVDNVFTYT
VKYGDTLSTIAEAMGIDVHVLGDINHIANIDLIFPDTILTANYNQHGQAT
NLTVQAPASSPASVSHVPSSEPLPQASATSQPTVPMAPPATPSDVPTTPF
ASAKPDSSVTASSELTSSTNDVSTELSSESQKQPEVPQEAVPTPKAAETT
EVEPKTDISEAPTSANRPVPNESASEEVSSAAPAQAPAEKEETSAPAAQK
AVADTTSVATSNGLSYAPNHAYNPMNAGLQPQTAAFKEEVASAFGITSFS
GYRPGDPGDHGKGLAIDFMVPENSALGDQVAQYAIDHMAERGISYVIWKQ
RFYAPFASIYGPAYTWNPMPDRGSITENHYDHVHVSFNA
>SPy0818 hypothetical protein
MILLKSLYKGFFAAMKEENFEARCYNREKGGCVLIKTMQYKKTMATVVAL
IVALLLFGLIYDLLGVQKNELAAQKSAQPKVKTARVVANGDILIHDILYM
SARKADDTYDFTPYFEYVKDWISGADLAIGDYEGTISPDYPLAGYPLFNA
PEEIAGALKNTGYDVVDLAHNHILDSQLDGALNTKKVFHQLGIDSIGIYD
KDRSKESFLIKNVNGIKIAILGYSYGYNGMEATLSQEDYEKHMSDLDEAK
IKKELQLAEKKADVTIVMPQMGTEYALEPTAEQKELYHKMIDWGADVVLG
GHPHVIEPSETVIKGRQKKFIIYSMGNFISNQRLETVDDIWTERGLLMDL
TFEKKDNKTKIKTVEAHPTMVLAKGKGIVGKEGFELYNYRTMVLEDFIKG
GKYHDKIDEETKAKVALAYQEINDLVNLKW
>SPy0944 hypothetical protein
MDPLKINIKFDGDFRQVVLKLANTFEPSELPQLDSFSNLQELTEELSISI
SQDFAHQLQPLIAQRIDELIQKQLP
>SPy1147 conserved hypothetical protein
MFRLLKRACSFLLLFVIYQSFVIHHNVQRVLAYKPMVEKTLAENDTKANV
DLVLAMIYTETKGGEADVMQSSESSSGQKNSITDSQASIEHGVNLLSHNL
ALAEEAGVDSWTAVQAYNFGTAYIDYIAEHGGQNTVDLATTYSKTVVAPS
LGNTSGQTYFYYHPLALISGGKLYKNGGNIYYSREVHFNLYLIELMSLF
>SPy1154 hypothetical protein
MVKKQKRRKIKSMSWARKLLIAVLLILGLALLFNKPIRNTLIARNSNKYQ
VTKVSKKQIKKNKEAKSTFDFQAVEPVSTESVLQAQMAAQQLPVIGGIAI
PELGINLPIFKGLGNTELIYGAGTMKEEQVMGGENNYSLASHHIFGITGS
SQMLFSPLERAQNGMSIYLTDKEKIYEYIIKDVFTVAPERVDVIDDTAGL
KEVTLVTCTDIEATERIIVKGELKTEYDFDKAPADVLKAFNHSYNQVST
>SPy1727 conserved hypothetical protein
MTTTEQELTLTPLRGKSGKAYKGTYPNGECVFIKLNTTPILPALAKEQIA
PQLLWAKRMGNGDMMSAQEWLNGRTLTKEDMNSKQIIHILLRLHKSKKLV
NQLLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFKS
EVATIVHGDIKHSNWVITTSGMIFLVDWDSVRLTDRMYDVAYLLSHYIPR
SRWSEWLSYYGYKNNDKVMQKIIWYGQFSHLTQILKCFDKRDMEHVNQEI
YALRKFREIFRKK
>SPy1832 hypothetical protein
MFQKLKNLIDRYSWFVFIMMILVLFLNYIYPFDPSLSGLQLEWLIMTQVF
PGLGIVCAMVAIIFKKFNLFVLALILYFALWLKLFLAFSFFTYFLGV
>SPy0135 putative fimbria-associated protein
MECYRDRQLLSTYHKQVTQKKPSEMEEVWQKAKAYNARLGIQPVPDAFSF
RDGIHDKNYESLLQIENNDIMGYVEVPSIKVTLPIYHYTTDEVLTKGAGH
LFGSALPVGGDGTHTVISAHRGLPSAEMFTNLNLVKKGDTFYFRVLNKVL
AYKVDQILTVEPDQVTSLSGVMGKDYATLVTCTPYGVNTKRLLVRGHRIA
YHYKKYQQAKKAMKLVDKSRMWAEVVCAAFGVVIAIILVFMYSRVSAKKS
K
>SPy1798 hypothetical protein sharing similarity with several eukaryotic proteins
MKKISKCAFVAISALVLIQATQTVKSQEPLVQSQLVTTVALTQDNRLLVE
EIGPYASQSAGKEYYKHIEKIIVDNDVYEKSLEGERTFDINYQGIKINAD
LIKDGKHELTIVNKKDGDILITFIKKGDKVTFISAQKLGTTDHQDSLKKD
VLSDKTVPQNQGTQKVVKSGKNTANLSLITKLSQEDGAILFPEIDRYSDN
KQIKALTQQITKVTVNGTVYKDLISDSVKDTNGWVSNMTGLHLGTKAFKD
GENTIVISSKGFEDVTITVTKKDGQIHFVSAKQKQHVTAEDRQSTKLDVT
TLEKAIKEADAIIAKESNKDAVKDLAEKLQVIKDSYKEIKDSKLLADTHR
LLKDTIESYQAGEVSINNLTEGTYTLNFKANKENSEESSMLQGAFDKRAK
LVVKADGTMEISMLNTALGQFLIDFSIESKGTYPAAVRKQVGQKDINGSY
IRSEFTMPIDDLDKLHKGAVLVSAMGGQESDLNHYDKYTKLDMTFSKTVT
KGWSGYQVETDDKEKGVGTERLEKVLVKLGKDLDGDGKLSKTELEQIRGE
LRLDHYELTDISLLKHAKNITELHLDGNQITEIPKELFSQMKQLRFLNLR
SNHLTYLDKDTFKSNAQLRELYLSSNFIHSLEGGLFQSLHHLEQLDLSKN
RIGRLCDNPFEGLSRLTSLGFAENSLEEIPEKALEPLTSLNFIDLSQNNL
ALLPKTIEKLRALSTIVASRNHITRIDNISFKNLPKLSVLDLSTNEISNL
PNGIFKQNNQLTKLDFFNNLLTQVEESVFPDVETLNLDVKFNQIKSVSPK
VRALIGQHKLTPQKHIAKLEASLDGEKIKYHQAFSLLDLYYWEQKTNSAI
DKELVSVEEYQQLLQEKGSDTVSLLNDMQVDWSIVIQLQKKASNGQYVTV
DEKLLSNDPKDDLTGEFSLKDPGTYRIRKALITKKFATQKEHIYLTSNDI
LVAKGPHSHQKDLVENGLRALNQKQLRDGIYYLNASMLKTDLASESMSNK
AINHRVTLVVKKGVSYLEVEFRGIKVGKMLGYLGELSYFVDGYQRDLAGK
PVGRTKKAEVVSYFTDVTGLPLADRYGKNYPKVLRMKLIEQAKKDGLVPL
QVFVPIMDAISKGSGLQTVFMRLDWASLTTEKAKVVKETNNPQENSHLTS
TDQLKGPQNRQQEKTPTSPPSAATGIANLTDLLAKKATGQSTQETSKTDD
TDKAEKLKQLVRDHQTSIEGKTAKDTKTKKSDKKHRSNQQSNGEESSSRY
HLIAGLSSFMIVALGFIIGRKTLFK
>SPy0601 putative endolysin, phage associated
MRRKIKPIVVLVFFILLAMVLIIGKRQANHAKQKEVEDAKSHIPIATSNP
GKAKTSTSETEDFILNPIVDVSGWQLPEEIDYDTLSRHISGAIVRVYGGS
QITAHNNAAFTTGIDKSFKTHIKEFQKRNVPVAVYSYALGRSTKEMKEEA
RAFYKNAAPYNPTYYWIDVEEATMKDMNKGVTAFREELKKLGAENVGLYI
GTYFMAEQDISTKGFDSVWIPTYGSDSGYYEAAPNTTLDYDLHQYTSQGY
LSGFNNALDLNQIAVTKDTKKTFEKLFGNSNN
>SPy0807 conserved hypothetical protein
MTSLGKNDKEVATVKKFKTLITGFINTRLGFIITLLFCYWIKTLWAYHTD
FSLDLGNIYQVFLTIINPIPLAFLLLGVALYVKNTRAFYICSWVVYIILN
ILLISNSIYYREFSDFITVSAMLASSKVSAGLGDSALNLLRIWDIIYILD
FIILISLSIAKKIKNDQRPFNKRAAFAITALSSLLLSINLFLAEIDRPEL
LTRGFSNTYIVRALGLPAFTLYSGNQTYQAQKERNGATAEELIDVKTYVK
GHYAAPDPQYFGIGKGKNIIVLHLESFQQFLIDYKLKEGDKEYEVTPFIN
SLYHSNATLAFPNFFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYGGEN
TQFATPSILAQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYFFDSSYFSK
QNSKNSFQYGLNDKYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGE
SSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLYDNSIFVL
YGDHYGISNSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGS
IKETFGGEIDALPTLLHILGIDTSQFVQLGQDLLSPQNSQIVAQRTSGTY
MTPEYTNYSGRLYNTQTGLEITNPDEMTIAKTKEIRSAVAQQLAASDAIQ
TGDLLRFDTQNGLKAIDPNQFIYTKQLKQLKDISAKLGSESTSLYSKNGH
KSTQKLFKAPSYLELNPVEADAATSELKEDNPKNKE
>SPy2032 putative ATP-binding cassette transporter-like protein
MFQLRKKMTRKQLALLSAGVLTCVVGGSYLIMNHQQQEIVSSVNKVKALT
IKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKEVFVKKGDVVKVG
QPLFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEIN
TLKSRYNTAPDESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKAN
ATATTEKGKLEYDTVKSDTAGTIVSLNTDLPNQSKSKKENETFMEIIDKS
KMLVKGNISEFDRDKLKIGQKVEVIDRKDNSKKWTGKVTQVGNLKAEEKG
QGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLIGSHTYVNVLNNVPEAG
KIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVEVTSGLTMQ
DKIAQPLPGMKDGMEVGSIVKP
>SPy0793 conserved hypothetical protein
MIKDTFLKTNWLNISHHIILLVFGFYFSFYSLAKELVSSTAQPVNYYAHL
LNVSFVGYIISLIGLSYYLSRQVSRQLFLKTSFIVISYLIVSYWVQITQH
LNDKRFDIWSLTKNQFYQFQALPSLLIILVMATLIKILAAYFAIEKDRFG
LLGYQGNTFSVALILAVVPINDIHLLKLISSRFSELVTAGNSQIALLKIS
GLLIVLLVIFATIIYVVLNALKHLKSNKPSFSVAATTSLFLALVFNYTFQ
YGVKGDEALLGYYVFPGATLFQIVAITLVALLAYVITNRYWPTTFFLLIL
GTIISVVNDLKESMRSEPLLVTDFVWLQELGLVTSFVKKSVIVEMVVGLA
ICIVVAWYLHGRVLAGKLFMSPVKRASAVLGLFIVSCSMLIPFSYEKEGK
ILSGLPIISALNNDNDINWLGFSTNARYKSLAYVWTRQVTKKIMEKPTNY
SQETIASIAQKYQKLAEDINKDRKNNIADQTVIYLLSESLSDPDRVSNVT
VSHDVLPNIKAIKNSTTAGLMQSDSYGGGTANMEFQTLTSLPFYNFSSSV
SVLYSEVFPKMAKPHTISEFYQGKNRIAMHPASANNFNRKTVYSNLGFSK
FLALSGSKDKFKNIENVGLLTSDKTVYNNILSLINPSESQFFSVITMQNH
IPWSSDYPEEIVAEGKNFTEEENHNLTSYARLLSFTDKETRAFLEKLTQI
NKPITVVFYGDHLPGLYPDSAFNKHIENKYLTDYFIWSNGTNEKKNHPLI
NSSDFTAALFEHTDSKVSPYYALLTEVLNKASVDKSPDSPEVKAIQNDLK
NIQYDVTIGKGYLLKHKTFFKISR
>SPy0510 putative sugar transferase
MTLLSIIVPCFNEEANILPYFEEMHQLETSMTNQLAFEYIFIDDGSKDNT
LGILRELAARFPNVHYLSFSRHFGKEAGLLAGLKEAKGNYITVMDVDLQD
PPELLPIMYAKLKEGYDIVGTRRQNRQGEPLIRSMCSNLFYGLIKHLSDT
EMVNGVRDYRLMTRQVVDSILELGEVNRFSKGIFSWVGYRITYLSFENQK
RKYGKSRWHFWELLRYSLDGFINFSEMPLTIATWTGTFSFLISIFAILFI
IIRKILFGDPVSGWASTVSIILFMGGIQLFCMGIIGKYISKIFLETKKRP
LYIIKEKH
>SPy0794 putative glycosyl transferase
MKKLIIIPAYNESSNIVNTIRTIESDAPDFDYIIIDDCSTDNTLAICQKQ
GFNVISLPINLGIGGAVQTGYRYAQRCGYDVAVQVDGDGQHNPCYLEKMV
EVLVQSSVNMVIGSRFITKEGFQSSFARRIGIKYFTWLIALLTGKKITDA
TSGLRLIDRSLIERFANHYPDDYPEPETVVDVLVSHFKVKEIPVVMNERQ
GGVSSISLTKSVYYMIKVTLAILVVRLKGNR
>SPy0516 putative glucosyl transferase
MRIGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRDVKRFED
PTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKHYNLDIIHTQTEFSLGLL
GKMIGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLD
GVICPSRIVLNLLEGYEVTIPKRVIPTGIPLEKYIRDDITAEEVTNLKAE
LGIAGDETMLLSLSRISYEKNIQAIINQMPAILAENAKIKLIIVGNGPYL
QDLKHLAMQLEVDKHVTFTGMVPHDKVALYYKACDFFISASTSETQGLTY
IESLASGTPIIAHGNPYLDDVVTDKMFGTLYYAETDLTDAIIDAILKTPV
MDKRLLAKKRYEISAQHFGKSIYTFYLDTLIARNSKEAQKLSLYLNHSGK
SSSLKLVQGAIHLPKRAAKVTAITSVKVVKAPIKLVHAIKDFLD
>SPy1134 putative ABC transporter (binding protein)
MSMPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALLSRSK
RWSDIMLQVTGVFQTIPSLALLGLFIPLMGIGTLPAVTALVIYAIFPILQ
NTITGLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVM
IIGTATLASLIGAGGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLL
QYLEKASLRRIMISFGITLLALLASYTPMALSQFSKGKDTVVIAGKLGAE
PDILINLYKELIEDQSDISVELKSNFGKTSFLYEALKSGDIDMYPEFTGT
ITSSLLRDKPPLSNDPKQVYEDAKKGIAKQDKLTLLKPFAYQNTYAVAMP
EKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGMQSQYGLQLSV
ATMEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGA
PLMKTSLLTKHPELKGILNQLAGKITEKEMQDMNYEVSVKGADANKVARD
YLLKTGLIQK
>SPy0836 conserved hypothetical protein
MSKRGKIKITTKTKLITASVITLVLIITGIVLWKQQRNTLTADIAKEPYS
TVSVTEGSIASSTLLSGTVKALSEEYIYFDANKGNDATVTVKVGDQVTQG
QQLVQYNTTTAQSAYDTAVRSLNKIGRQINHLKTYGVPAVSTETNRDEAT
GEETTTTVQPSAQQNANYKQQLQDLNDAYADAQAEVNKAQIALNDTVVIS
SVSGTVVEVNNDIDPSSKNSQTLVHVATEGQLQVKGTLTEYDLANVKVGQ
SVKIKSKVYSNQEWTGKISYVSNYPTESNAGSTTPAGSTGAGSSTGATYD
YKIDIISPLNQLKQGFTVSVEVVNEAKQALVPLTAVIKKDKKHYVWTYDD
ATGKAKKVEVTLGNADAQQQEIHKGVAVGDIVIANPDKNIKPDKKLEGVI
SIGTNTKPEKDSQSKNKKSGVDK
>SPy1666 conserved hypothetical protein
MKSFSLTFSFLNLLKYGTIKVMTKEFHHVTVLLHETVDMLDIKPDGIYVD
ATLGGSGHSAYLLSKLGEEGHLYCFDQDQKAIDNAQVTLKSYIDKGQVTF
IKDNFRHLKARLTALGVDEIDGILYDLGVSSPQLDERERGFSYKQDAPLD
MRMDRQSLLTAYEVVNTYPFNDLVKIFFKYGEDKFSKQIARKIEQARAIK
PIETTTELAELIKAAKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESI
QDAMELLALDGRISVITFHSLEDRLTKQLFKEASTVDVPKGLPLIPEDMK
PKFELVSRKPILPSHSELTANKRAHSAKLRVAKKIRK
>SPy1093 putative D,D-carboxypeptidase, penicillin-binding protein
MIKRWVILFFMVLTCSGFGKTVLAADFQVGAEHAIVVEADSGRVLYEKDA
KTPDAIASLTKLVTAYLVLDKVKSGQLQLSDQVNLSDYAFELTKDRSLSN
VPFDKKTYSVQDLLTATLVASSNSAAIALAEKVAGSELHFVNQMREQLSH
WGITSGKILNASGLPNEVLKDHRYPGSALEEENMLSAQDVAIVTMHLLED
FPEILEITKQTEVDFAGNSIKSFNQLLPGMAKGRAGVDGLKTGTTDLAGH
CLVVTSIENGMRLITVILNADGSDKNQNTRFEQANRLLDYVARTYCRRKI
LKKGSLVSERSLPIQDGQVKELPISVAEDVTIILQQGEQVPKPKQFMISE
TSLLAPITKGEVVAYLTSPRITDQSVRYLKEPKRIPLKASQSLKKASDLQ
LWWRDFLEKRR
>SPy0716 agaS, putative tagatose-6-phosphate aldose/ketose isomerase
MFTKTQEALEALGAAITTKEIKQEPRLWQETMTFFEETRDSLDSFLKRVC
NSANRNNVHVIFTGAGTSEYIGNTICPYLKKVGNRQRYLFESVASTDLVA
APDYYLVEEETVLLVSFARSGNSPESVAAVNLVNQLVPNSYHLTITCAKD
GELAKKAQQDERSYLYLMPEDANDAGFAMTGSFTCMMLAALLIFDDANSI
AQKEAYVTDMILAGQAVIDQERRLQELADLGFERLVYLGSAGLAKLTQEA
QLKMLELTAGQVATLYESFMGFRHGPKSFINDRTLVIGFVNNDAYVRQYD
LDMLEEIQADGIALKILALLQGGDINFSEDQFRLDTRHLLPDAYLAFPMI
LVAQTLALLTAVTLGNSPDTPSATGTVNRVVKGVTIHPYPTSSRQCNKA
>SPy1802 alr, putative alanine racemase
MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAYGHGAVQ
VSKALLPQVDGYCVSNLDEALQLRQAGIDKEILILGVLLPNELELAVANA
ITVTIASLDWIALARLEKKECQGLKVHVKVDSGMGRIGLRSSKEVNLLID
SLKELGADVEGIFTHFATADEADDTKFNQQLQFFKKLIAGLEDKPRLVHA
SNSATSIWHSDTIFNAVRLGIVSYGLNPSGSDLSLPFPLQEALSLESSLV
HVKMISAGDTVGYGATYTAKKSEYVGTVPIGYADGWTRNMQGFSVLVDGQ
FCEIIGRVSMDQLTIRLPKAYPLGTKVTLIGSNQQKNISTTDIANYRNTI
NYEVLCLLSDRIPRIY
>SPy0933 cpsFO, glucose-1-phosphate thymidyl transferase
MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLAGIKDVL
IISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDD
RVALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDE
NMNAISIEEKPEVPKSHFAVTGLYFYDNDVVEIAKNIKPSARGELEITDV
NKAYLERGDLSVELMGRGFAWLDTGTHESLLEAAQYIETVQRLQNAQVAN
LEEIAYRMGYISKEDVHKLAQSLKKNEYGQYLLRLIGEA
>SPy0935 cpsFP, putativedTDP-4-keto-6-deoxyglucose-3,5-epimerase
MTETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEKMLPIGF
PERFFEEGKLQNNVSFSRQHVLRGLHAEPWDKYISVADDGKVLGAWVDLR
EGETFGNVYQTVIDASKGMFVPRGVANGFQVLSETVSYSYLVNDYWALDL
KPKYAFVNYADPSLGITWENLAAAEVSEADKNHPLLSDVKPLKPKDL
>SPy0936 cpsFQ, putative dTDP-glucose-4,6-dehydratase
MYKNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNRANIEAIL
GDRVELVVGDIADAELVDKLAAKTDAIVHYAAESHNDNSLEDPSPFIHTN
FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGQGEGPGEKFTAE
TKYNPSSPYSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFI
PRQITNILAGIKPKLYGEGKNVRDWIHTNDHSTGVWAILTKGRIGETYLI
GADGEKNNKEVLELILEKMGQPKDAYDHVTDRAGHDLRYAIDSTKLREEL
GWEPQFTNFSEGLEETIKWYTENETWWKAEKDAVEAKYAKTQEVIK
>SPy0292 dacA, penicillin-binding protein (D-alanyl-D-alanine carboxypeptidase)
MIKRLISLVVIALFFAASTVSGEEYSVTAKHAIAVDLESGKVLYEKDAKE
VVPVASVSKLLTTYLVYKEVSKGKLNWDSPVTISNYPYELTTNYTISNVP
LDKRKYTVKELLSALVVNNANSPAIALAEKIGGTEPKFVDKMKKQLRQWG
ISDAKVVNSTGLTNHFLGANTYPNTEPDDENCFCATDLAIIARHLLLEFP
EVLKLSSKSSTIFAGQTIYSYNYMLKGMPCYREGVDGLFVGYSKKAGASF
VATSVENQMRVITVVLNADQSHEDDLAIFKTTNQLLQYLLINFQKVQLIE
NNKPVKTLYVLDSPEKTVKLVAQNSLFFIKPIHTKTKNTVHITKKSSTMI
APLSKGQVLGRATLQDKHLIGQGYLDTPPSINLILQKNISKSFFLKVWWN
RFVRYVNTSL
>SPy1421 ddlA, putative D-ala,D-ala ligase
MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFITQMGQFI
KTQQFSEKPSESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGED
GSIQGFLEVLRMPYIGTNVMSSSIAMDKITTKRVLESIGIPQVAYTVYID
GQDLEACLVETLARLTFPIFVKPANMGSSVGISKAQTKVELRKAIQLALT
YDSRVLIEQGVVAREIEVGLLGNDKVKSTLPGEVIKDVDFYDYQAKYVDN
KITMAIPADVDQSIVTEMRSYAEVAFKALGGCGLSRCDFFLTQDGQVYLN
ELNTMPGFTQWSMYPLLWENMGLAYPDLIEELVTLAQEMFDQRESHLI
>SPy0475 dgk, putative diacylglycerol kinase
MALHDNNTTKRKWKNRTITSSLEFALTGVFTAFKEERNLRSHLLSACLAC
VAGLFFSISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAK
NAKDMAAGAVLMISGYAVLTGLIIFIPKIWNIFVH
>SPy1523 divIB, cell division protein
MAKDKEKQSDDKLVLTEWQKRNIEFLKKKKQQAEEEKKLKEKLLSDKKAQ
QQAQNASEAVELKTDEKTDSQEIESETTSKPKKTKKVRQPKEKSATQIAF
QKSLPVLLGALLLMAVSIFMITPYSKKKEFSVRGNHQTNLDELIKASKVK
ASDYWLTLLTSPGQYERPILRTIPWVKSVHLSYQFPNHFLFNVIEFEIIA
YAQVENGFQPILENGKRVDKVRASELPKSFLILNLKDEKAIQQLVKQLTT
LPKKLVKNIKSVSLANSKTTADLLLIEMHDGNVVRVPQSQLTLKLPYYQK
LKKNLENDSIVDMEVGIYTTTQEIENQPEVPLTPEQNAADKEGDKPGEHQ
EQTDNDSETPANQSSPQQTPPSPETVLEQAHG
>SPy1311 dltB, putative integral membrane protein
MMMFFSHIPYMEPYGNPIYFVYLILAFLPVIIGIFKQKRLSTYETLVSLV
FILFMFGGDHYQQLVAFLFYLLWQIISVFAYQKYRENANSAGVFYLAIAM
ALFPLIWVKVAPLTGPSSQTLFSFLGISYLTFKSIGMIIEMRDGTLQEVR
LPDFIRFMIFFPTFSSGPIDRFRHFQEDYHKLPERDDYFAMLNKAVMYLM
LGFLYKHIISYCLGGILLPLLENKALMVGGYFNKETILVMYVYGLNLFFD
FAGYSMFAIGISYLLGIRTPENFNMPFLSASLKDFWNRWHMSLSFWFRDY
VFMRLVHLLIKHKTFKNRNVTSGVAYLVNMLVMGFWHGLTWYYIAYGLFH
GIGLIINDAWIRKKKEINRHRKKKGLSPLFQSRAFHVLCIVVTFHVVMFS
LLLFSGFLNDLWFNRPLH
>SPy1309 dltD, putative extramembranal protein
MLKRLWLILGPLLIAFVLVVITIFSFPTQLDHSIAQEKANAVAITDSSFK
NGLIKRQALSDETCRFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIG
KRGSASLSHYYGIQQITNEMQKKKAIFVVSPQWFTAQGINPSAVQMYLSN
TQVIEFLLKARTDKESQFAAKRLLELNPGVSKSNLLKKVSKGKSLSRLDR
AILKCQHQVALREESLFSFLGKSTNYEKRILPRVKGLPKVFSYKQLNALA
TKRGQLATTNNRFGIKNTFYRKRIAPKYNLYKNFQVNYSYLASPEYNDFQ
LLLSEFAKRKTDVLFVITPVNKAWADYTGLNQDKYQAAVRKIKFQLKSQG
FHRIADFSKDGGESYFMQDTIHLGWNGWLAFDKKVQPFLETKQPVPNYKM
NPYFYSKIWANRKDLQ
>SPy0737 epf, putative extracellular matrix binding protein
MRKVKKVFVSSCMLLTVGLGVAVPTGFSQSNGVMVVKAAEVPATDLSRQA
SDSERVDESSLLQKENLSVDSFKLENLNGWEAENDTAGNLGKFKDPDSSG
YQNILTSSGKNISVAVAPKGSGKMNIKVTKRSNFQGGYYVGGLRTQTPVL
KLNDVYRYSFTTKKLSGNSSEFKTRVKPVESNNKLGKELVIRVDNKNVST
KHDWLPDISDGTHTVDFTGLDKKLSVAFRFSPRQTSNVVYEFSNINIKNI
SPASVPAIPSKVLEGTSVLSGTAISSGDTLEKRKSFDGDILRVYKDSKII
ARTVIKGNKWDVKLSKPLIAGEKLDFEILHPRSQNVSKKISKQVEAKPFD
PASYKEKVIAKLKPVYEATSEKITNDAWLDENAKDLQKQKLEEQYISGKV
AISEAGTKQEAIDAAYNKYSSQTDPDSLPSQYKQGNKENEQEKGRQDLIQ
TRDLTLKAIQEDKWLTEQEKTIQKEEALKAFETGIESVNQTVSLEQLKQR
LIVYKASEKDSEKKEYPESIPNQHIPGKEKEVKAAKQEELKKLHDTTLEK
INQDKWLTPDQQAEQLKQAEVTFKKGQEAIKSAQTLTQLETDLADYVSEN
EGKGNSIPDKYKSGNKDDLVNKAEVKLKEAHEATKQAIEKDPWLSPEQKK
AQKEKAKARLDEGLKALKAADSLEILKVTEEAFVDKEKNPDSIPNQHKAG
TADQARKQALDSLDKEVQKELESIDNDNTLTTDEKAAAKKKVNDAYDVAK
QTAMEANSYEDLTTIKDEFLSNLPHKQGTPLKDQQSDAIAELEKKQQEIE
KAIEGDKTLPRDEKEKQIADSKERLKSDTQKVKDAKNADAIKKAFEEGKV
NIPQAHIPGDLNKDKEKLLAELKQKADDTEKAIDVDKTLTEDEKKEQKVK
TKAELEKAKTDVKNTQTREELDKKVPELKKAIEDTHVKGNLEGVKNKAIE
DLKKAHTETVAKINGDDTLDKATKEAQVKEADKALAAGKDAITKADDADK
VSTAVTEHTPKIKAAHKTGDLKKAQVDANTALDKAAEKERGEINKDATLT
TEDKAKQLKEVETALTKAKDNVKAAKTADAINDARDKGVATIDAVHKAGQ
DLGARKSGQVAKLEEAAKATKDKISADPTLTSKEKEEQSKAVDAELKKAI
EAVNAADTADKVDDALGEGVTDIKNQHKSGDSIDARREAHGKELDRVAQE
TKGAIEKDPTLTTEEKAKQVKDVDAAKERGMAKLNEAKDADALDKAYGEG
VTDIKNQHKSGDPVDARRGLHNKSIDEVAQATKDAITADTTLTEAEKETQ
RGNVDKEATKAKEELAKAKDADALDKAYGDGVTSIKNQHKSGKGLDVRKD
EHKKALEAVAKRVTAEIEADPTLTPEVREQQKAEVQKELELATDKIAEAK
DADEADKAYGDGVTAIENAHVIGKGIEARKDLAKKDLAEAAAKTKALIIE
DKTLTDDQRKEQLLGVDTEYAKGIENIDAAKDAAGVDKAYSDGVRDILAQ
YKEGQNLNDRRNAAKEFLLKEADKVTKLINDDPTLTHDQKVDQINKVEQA
KLDAIKSVDDAQTADAINDALGKGIENINNQYQHGDGVDVRKATAKGDLE
KEAAKVKALIAKDPTLTQADKDKQTAAVDAAKNTAIAAVDKATTTEGINQ
ELGKGITAINKAYRPGEGVKARKEAAKADLEKEAAKVKALITNDPTLTKA
DKAKQTEAVAKALKAAIAAVDKATTAEGINQELGKGITAINKAYRPGEGV
KARKEAAKADLEREAAKVREAIANDPTLTKADKAKQTEAVAKALKAAIAA
VDKATTAEGINQELGKGITAINKAYRPGEGVEAHKEAAKANLEKVAKETK
ALISGDRYLSETEKAVQKQAVEQALAKALGQVEAAKTVEAVKLAENLGTV
AIRSAYVAGLAKDTDQATAALNEAKQAAIEALKQAAAETLAKITTDAKLT
EAQKAEQSENVSLALKTAIATVRSAQSIASVKEAKDKGITAIRAAYVPNK
AVAKSSSANHLPKSGDANSIVLVGLGVMSLLLGMVLYSKKKESKD
>SPy0443 gcaD, putative UDP-N-acetylglucosamine pyrophosphorylase
MTNYAIILAAGKGTRMTSDLPKVLHKVSGLTMLEHVFRSVKAISPEKSVT
VIGHKSEMVRAVLADQSAFVHQTEQLGTGHAVMMAETQLEGLEGHTLVIA
GDTPLITGESLKSLIDFHVNHKNVATILTATAQDPFGYGRIVRNKDGEVI
KIVEQKDANEYEQQLKEINTGTYVFDNKRLFEALKCITTNNAQGEYYLTD
VVAIFRANKEKVGAYILRDFNESLGVNDRVALAIAETVMRQRITQKHMVN
GVTFQNPETVYIESDVEIAPDVLIEGNVTLKGRTHIGSGTVLTNGTYIVD
SEIGDNCVVTNSMIESSVLAAGVTVGPYAHLRPGTTLDREVHIGNFVEVK
GSHIGEKTKAGHLTYIGNAQVGSSVNVGAGTITVNYDGQNKYETVIGDHA
FIGSNSTLIAPLEVGDHALTAAGSTISKTVPIDSIAIGRSRQVTKEGYAK
RLAHHPSRSK
>SPy0329 gidB, putative glucose-inhibited division protein
MTPQDFYRTLEEDGFSLSSKQKEQFDTYFKSLVEWNTKINLTAITEENEV
YLKHFYDSIAPILQGFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTII
DSLNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDVVTARAV
ARMQVLSELTIPFLKIGGKLIALKAQAADQELEEAKNALCLLFGKVIKNH
SYQLPNGDSRFITIVEKKKETPNKYPRKAGLPNKKPL
>SPy1280 glmS, putative L-glutamine-D-fructose-6-phosphate amidotransferase
MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNLIKSVGR
IADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNG
VIENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKSL
SIIEGSYAFALMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRE
TSEFMEIHDKELVILTKDKVTVTDYDGKELIRDSYTAELDLSDIGKGTYP
FYMLKEIDEQPTVMRQLISTYADETGNVQVDPAIITSIQEADRLYILAAG
TSYHAGFATKNMLEQLTDTPVELGVASEWGYHMPLLSKKPMFILLSQSGE
TADSRQVLVKANAMGIPSLTVTNVPGSTLSREATYTMLIHAGPEIAVAST
KAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKD
LVAEKVQALLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGE
LKHGTISLIEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEG
LDREGDDIIVNKVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKA
VTVE
>SPy0361 glr, putative glutamate racemase
MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGPRPKKQI
KEYTWELVNFLLTQNVKMIVFACNTATAVAWEEVKAALDIPVLGVVLPGA
SAAIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSIQVRSLACPKFVPI
VESNEMCSSIAKKIVYDSLAPLVGKIDTLVLGCTHYPLLRPIIQNVMGPS
VKLIDSGAECVRDISVLLNYFDINGNYHQKAVEHRFFTTANPEIFQEIAS
IWLKQKINVEHVTL
>SPy2200 hasA, hyaluronate synthase
MPIFKKTLIVLSFIFLISILIYLNMYLFGTSTVGIYGVILITYLVIKLGL
SFLYEPFKGKPHDYKVAAVIPSYNEDAESLLETLKSVLAQTYPLSEIYIV
DDGSSNTDAIQLIEEYVNREVDICRNVIVHRSLVNKGKRHAQAWAFERSD
ADVFLTVDSDTYIYPNALEELLKSFNDETVYAATGHLNARNRQTNLLTRL
TDIRYDNAFGVERAAQSLTGNILVCSGPLSIYRREVIIPNLERYKNQTFL
GLPVSIGDDRCLTNYAIDLGRTVYQSTARCDTDVPFQLKSYLKQQNRWNK
SFFKESIISVKKILSNPIVALWTIFEVVMFMMLIVAIGNLLFNQAIQLDL
IKLFAFLSIIFIVALCRNVHYMIKHPASFLLSPLYGILHLFVLQPLKLYS
LCTIKNTEWGTRKKVTIFK
>SPy2201 hasB, UDP-glucose 6-dehydrogenase
MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSPIQDEYI
EYYLKSKQLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETV
IKEVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALY
DNLYPSRIIVSCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEA
EAVKLFANTYLALRVAYFNELDTYAESRKLNSHMIIQGISYDDRIGMHYN
NPSFGYGGYCLPKDTKQLLANYNNIPQTLIEAIVSSNNVRKSYIAKQIIN
VLEERESPVKVVGVYRLIMKSNSDNFRESAIKDVIDILKSKDIKIIIYEP
MLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNKVYSRDIFN
RD
>SPy2202 hasC, UDP-glucose pyrophosphorylase
MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGI
EEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKNELLKLVDETTAINLHF
IRQSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLME
DYDKTHASTIAVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPED
APSDLAIIGRYLLTPEIFGILERQTPGAGNEVQLTDAIDTLNKTQRVFAR
EFKGNRYDVGDKFGFMKTSIDYALEHPQVKEDLKNYIIKLGKALEKSKVP
THSK
>SPy0224 hasC.2, putative UDP-glucose pyrophosphorylase
MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGI
EEILIVTGKSKRSIEDHFDSNFELEYNLQAKGKIELLKLVDETTSINLHF
IRQSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQLID
DYEETHAATIAVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQPQD
APSDLAIIGRYLLTPEIFSILEKQEPGAGNEVQLTDAIDTLNKTQRVFAR
EFKGKRYDVGDKFGFMKTSLDYALKHPQVKDDLKAYIIQLGKALEKTKP
>SPy1053 lepA, GTP-binding protein
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLL
DSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRS
LAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPE
RVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPL
QALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFT
PKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQM
NPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCG
FLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFP
DPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVN
VIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGD
KVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARS
DIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLS
VLSMDDDTKK
>SPy0585 lgt, putative prolipoprotein diacylglycerol transferase
MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSDAIFDFI
LIAFPLAIVGARIYYVIFEWSYYVKHLDEIIAIWNGGIAIYGGLITGALV
LLAYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNY
LPSFIQKQMFIEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIF
AFYLIWYGSGRLVIEGMRTDSLMFLGIRISQYVSALLIIIGLIFVIKRRR
QKGISYYQE
>SPy0826 lsp, putative prolipoprotein signal peptidase
MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLTYLQNNG
AAFSILQDQQWFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGI
GNFIDRLRLAYVIDMIHLDFVDFAIFNVADSYLTVGVILLLICLWKEEDY
GN
>SPy1006 lys, putative lysin-phage associated
MATYQEYKSRSNGNAYDIDGSLGAQCWDGYADYCKYLGLPYANCTNTGYA
KDIWEQRHKNGILNYFDEVETMQAGDVAIFMVVAGVTPYSHVAIFDSDAG
SGYGWFLGQNQGGANGAYNLVKIPYSTTYPTAFRPKVFKNAVTVIGNIGL
NKGDYFIDVSAYQQADLTATCQQAGTTKTIIKVSESLAWLSDRHQQQANT
SDPIGYYHFGRFGGDSNLAQREADLFLSNLPTKKVSYLVIDYEDSASADK
EANTNAVIAFMDKIANAGYKPVYYSYKPFTLNNIDYQQIIAKYPNSIWIA
GYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAGGLDKNIVLLADDSSKV
DIPKIDKPQSQLTFNQKLDTNTKLDNSNVPYYEATLRTDYYVESKPNASS
ADKEFIKAGTRVRVYEKVNGWSRINASQSDQWVEDKYLSNATQV
>SPy1662 mraY, putativeundecaprenyl-phosphate-UDP-MurNAc- pentapeptide phospho-MurNAc-pentapeptide transferase
MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHLAKAGTP
TMGGTVFLLVATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDD
FLKIFKQINEGLTAKQKLALQLVGGLMFYFLHVSPSGISSINVFGYQLPL
GIFYLFFVLFWVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQSQF
DVLLLIGAMIGALLGFFCFNHKPAKVFMGDVGSLALGAMLAAISIALRQE
WTLLIIGIVYVLETSSVMLQVSYFKYTKKKYGEGRRIFRMTPFHHHLELG
GLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILYVF
>SPy0780 mscL, putative large conductance mechanosensitive channel
MVKELKAFLFRGNIIELAVAVIIGGAFGAIVTSFVNDIITPLILNPALKA
ANVENITQLSWNGVKYGSFLGAVINFLIIGTSLFFVVKAAEKAMPKKEKE
AAAPTQEELLTEIRDLLAQK
>SPy1101 murB, putative UDP-N-acetylenolpyruvoylglucosamine reductase
MITELHGIDIRENEPLKHYTYTKVGGPADFLAFPRNHYELSRIVAYANKE
NMPWLVLGNASNLIVRDGGIRGFVIMFDKLNAVHLNGYTLEAEAGANLIE
TTKIAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEISHIFLSAKVLTP
SGEIKTISARDMAFGYRHSAIQETGDIVISAKFALKPGNYDTISQEMNRL
NHLRQLKQPLEFPSCGSVFKRPPGHFAGQLIMEANLKGHRIGGVEVSEKH
TGFMINVADGTAKDYEDLIAYVIETVENHSGVRLEPEVRIIGENL
>SPy0345 murC, putative UDP-N-acetyl muramate-alanine ligase
MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGLEQAGIT
ILPFSEDNITPDMELIVGNAFRENNKEVAYALRHQIPFKRYHDFLGDFMK
SFISFAVAGAHGKTSTTGLLSHVLKNITDTSYLIGDGTGRGSANAQYFVF
ESDEYERHFMPYHPEYSIITNIDFDHPDYFTGIADVRNAFNDYAKQVKKA
LFVYGEDDELKKIEAPAPIYYYGFEEGNDFIAYDITRTTNGSDFKVKHQG
EVIGQFHVPAYGKHNILNATAVIANLFVAGIDMALVADHLKTFSGVKRRF
TEKIINDTIIIDDFAHHPTEIVATIDAARQKYPSKEIVAIFQPHTFTRTI
ALLEDFACALNEADSVYLAQIYGSAREVDKGEVKVEDLAAKIIKPSQVVT
VENVSPLLDHDNAVYVFMGAGDIQLYEHSFEELLANLTKNNQ
>SPy1525 murD, putative UDP-N-acetylmuramoylalanine-D-glutamate ligase
MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFDQNPAAQ
ALLEEGIKVICGSHPVELLDENFEYMVKNPGIPYDNPMVKRALAKEIPIL
TEVELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYP
ASKVVQKAIAGDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSF
EDYVAAKWMIQAQMTESDYLILNANQEISATLAKTTKATVIPFSTQKVVD
GAYLKDGILYFKEQAIIAATDLGVPGSHNIENALATIAVAKLSGIADDII
AQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNILATQKALSGFDNSRLI
LIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKAEVSYLEAR
NVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRG
DA
>SPy0388 murE, putativeUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelateligase
MITIEQLLDILKKDHNFREVLDADGYHYHYQGFSFERLSYDSRQVDGKTL
FFAKGATFKADYLKEAITNGLQLYISEVDYELGIPVVLVTDIKKAMSLIA
MAFYGNPQEKLKLLAFTGTKGKTTAAYFAYHMLKESYKPAMFSTMNTTLD
GKTFFKSQLTTPESLDLFAMMAECVTNGMTHLIMEVSSQAYLVDRVYGLT
FDVGVFLNISPDHIGPIEHPTFEDYFYHKRLLMENSRAVVINSGMDHFSF
LADQVADQEHVFYGPLSDNQITTSQAFSFEAKGQLAGHYDIQLIGHFNQE
NAMAAGLACLRLGASLADIQKGIAKTRVPGRMEVLTMTNHAKVFVDYAHN
GDSLEKLLSVVEEHQTGKLMLILGAPGNKGESRRADFGRVIHQHPNLTVI
LTADDPNFEDPEDISKEIASHIARPVEIISDREQAIQKAMSLCQGAKDAV
IIAGKGADAYQIVKGQQVAYAGDLAIAKHYL
>SPy1420 murF, putative D-Ala-D-Ala adding enzyme
MKLTLHEVAKIVDAQNNVSDLDDVPLHHIEFDSRKITKGDLFLPLKGQRD
GHEFIDLAFQNGAVATFSEKELPGKPHLLVEDCLKAFQKLAHYYIDKMRV
DVIAVTGSNGKTSTKDMIGAVLSTTYKTYKTQGNYNNEIGLPYTVLHMPD
DTEKIVLEMGQDHMGDIRLLSEIARPRIAVLTLVGEAHLEYFGSRDKIAQ
GKMQIVDGMNSDGILIAPGDPIIDPYLPENQMVIRFGNQQEIDVTGIQED
KDSLTFTTNVLATPVSLPLPGKYNATNAMVAAYVGKLLAVTDEDIIAALQ
TVTLTGNRTEWKKAANGADILSDVYNANPTAMRLILETFANIAKNPGGKK
IAVLADMKELGKDSVILHSQLIDSLTSGNIDQLVFYGDHIKELARLASQV
YPAEQVHYFLKTEQEDQFEAMAQYVQNILNPFDQILLKGSHSMSLEKLVD
RLVTDKNCDSYQP
>SPy1524 murG, putative undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase
MPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEHTEIEKS
GLDVTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKLRPQALFS
KGGFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQE
DQLSKVKHLGAVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAG
AHVFNQFISDHPELKQRYNIINITGDPHLNELSSHLYRVDYVTDLYQPLM
AMADLVVTRGGSNTLFELLAMAKLHLIVPLGKEASRGDQLENATYFEKRG
YAKQLQEPDLTLHNFDQAMADLFEHQADYEATMLATKEIQSPDFFYDLLR
ADISSAIKEK
>SPy1358 murZ, putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase
MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDV
DSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGS
LLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNG
QKIHGAHIYMDTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLL
NNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTYIALAAAIGKG
VKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPY
PGFATDLQQPLTPLLLKADGRGTIIDTIYEKRINHVPELMRMGADISVIG
GQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITNIEFILRGY
ASIIAKLTALGADIQLIED
>SPy0257 nanH, putative acylneuraminate lyase
MTDLTKYQGIIPAFYACYDDQGNISPERVRALTQYYIDKGVQGLYINGSS
GECIYQSVFDRQLVLENVMAVAKGKLTIINHVACNNTKDSIELAAHSERL
GVDAIAAIPPIYFRLPEYAVADYWNAISSAAPHTDFIIYNIPQLAGVALT
PSLYKTMLANKRVIGVKNSSMPVQDIQTFCAIGGDDHIVFNGPDEQFLGG
RLMGAAAGIGGTYGAMPELFLRLNQLIADKDLEKAKALQYTINEIIGVLV
SAHGNMYGVIKEVLRINEGLDIGSVRSPLAELVEEDRVICQRAAALINQA
KETF
>SPy1649 pbp1A, putative penicillin-binding protein 1a
MITIKNPKILKWLKYVLSAILSLIILVIIIGGLLFTFYISSAPKLSEAQL
KSTNSSLVYDGNNNLIADLGSEKRENVTADSIPINLVNAITSIEDKRFFN
HRGVDLYRIFGAAFHNLTSQTTQGGSTLDQQLIKLAYFSTNESDQTLKRK
AQEVWLALQMERKYTKQEILTFYINKVYMGNGNYGMLTAAKSYYGKDLKD
LSYAQLALLAGIPQAPSQYDPYLHPEAAQNRRNVVLQQMYMEKHLTKAEY
ETAIATPVAEGLQSLQQRSTYPKYMDNYLKQVIEEVKKETNKDIFTAGLK
VYTNIIPDAQQTLYNIYHSGDYVYYPDQDFQVASTIVDVTNGHVIAQLGG
RNQDENVSFGTNQAVLTDRDWGSTMKPITAYAPAIESGVYTSTAQSTNDS
VYYWPGTTTQLFNWDLRYNGWMTIQAAIMLSRNVPAVRALEAAGLDYARS
FLSSLGINYPEMHYSNAISSNNSSSDKKYGASSEKMAAAYAAFANGGIYH
KPRYVNKVEFSDGTSKTFDEKGKRAMKETTAYMMTDMLKTVLTYGTGTAA
AIPGVAQAGKTGTSNYTDEELAKIGEKYGLYPDYVGTLAPDENFVGFTKR
YAMAVWTGYKNRLTPVYGSSLEIASDVYRSMMTYLTNGYSEDWTMPNGLY
RSGGFLYLSGTYASNTDYTNSVYNNLYSNNTTTASSQTTSDDTSSSNDTS
NSTNTDNNGSHPSTDDKKTTH
>SPy0097 pbp1b, putative penicillin-binding protein 1b
MRYFMVKWNTKQKRISHQRLGLLDLGPVLLRTLRLLSNFFYIVIFLFGMM
GFGMAFGYLASQIESVKVPSKESLVKQVESLTMISQMNYSDNSLISTLDT
DLLRTPVANDAISENIKKAIVSTEDEHFQEHKGIVPKAVFRATLASVLGF
GEASGGSTLTQQLVKQQVLGDDPTFKRKSKEIVYALALERYMSKDNILCD
YLNVSPFGRNNKGQNIAGVEEAARGIFGVSAKDLTVPQAAFLAGLPQSPI
VYSPYLSTGQLKSEKDMAYGIKRQQNVLFNMYRTGVLSKKEYEDYKAYPI
QKDFIQPGSAIVNNHDYLYYTVLADAKKAMYSYLIKRDKVSSRDLKNDET
KAAYEERALTELQQGGYTITTTINKPIYNAMQTAAAQFGGLLDDGTGTVQ
MGNVLTDNATGAVLGFVGGRDYALNQNNHAFNTVRSPGSSIKPIIAYGPA
IDQGLMGSASVLSNYPTTYSSGQKIMHADSEGTAMMPLQEALNTSWNIPA
FWTQKLLREKGVDVENYMTKMGYKIADYSIESLPLGGGIEVSVAQQTNAY
QMLSNNGLYQKQYIVDKITASDGTVVYKHENKPIRIFSAATATILQELLR
GPITSGATTTFKNRLAAINPWLANADWIGKTGTTENYTDVWLVLSTPKVT
LGGWAGHDDNTSLAPLTGYNNNSNYLAYLANAINQADPNVIGVGQRFNLD
PGVIKANVLKSTGLQPGTVNVNGHTFSVGGEMTTSLWSQKGPGAMTYRFA
IGGTDADYQKAWGNFGFRKN
>SPy2059 pbp2A, penicillin-binding protein 2a
MRFLELLQKKFFPKAYQEKQFLMHQKTRLTPQHNQKQYSPNANHLDSSAT
KNSEQDPATALQRSRAYEGSPKSRPAWLQKLEAVLPSPQRPIRRFWRRYH
IGKLLMILIGTLVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDHKGEYA
GSLSGQKGSYVELNAISDDLENAVIATEDRTFYSNSGINLKRFLLAVVTA
GRFGGGSTITQQLAKNAYLSQDQTIKRKAREFFLALELTKKYSKKDILTM
YLNNSYFGNGVWGVEDASQKYFGTTAANLTLDEAATLAGMLKGPEIYNPY
HSLKNATHRRDTVLGAMVDAKKITQTKAQQARAVGLKNRLADTYVGKTDD
YKYPSYFDAVISEAIATYGLSEKDIVNNGYKVYTELDQNYQTGMQTTFNN
DELFPVSAYDGSSAQAASVALDPKTGGVRGLIGRVNSSENPTFRSFNYAT
QAKRSPASTIKPLVVYAPAVASGWSIEKELPNTVQDFDGYQPHNYGNYES
EDVPMYQALANSYNIPAVSTLNDIGIDKAFTYGKTFGLDMSSAKKELGVA
LGGSVTTNPLEMAQAYAAFANNGVIHPAHLINRIENARGEVLKTFTDKAK
RVVSQSVADKMTAMMLGTFSNGTAVNANVYGYTLAGKTGTTETNFNPDLA
GDQWVIGYTPDVVISQWVGFNQTDENHYLTDSSAGTASAIFSTQASYILP
YTKGSQFHVDNAYAQNGISAVYGVNETGNQSGVDTQSIIDGLRKSAQEAS
QSLSKAVDQSGLRDKAQSIWKEIVDYFR
>SPy1664 pbpX, putative penicillin binding protein 2X
MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIINFMIIIG
TDQKFGVSLSEGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAI
LDKSFVSASDEKLYVQPSQYETVADILKKHLGMKKTDVIKQLKRKGLFQV
SFGPSGSGISYSTMSTIQKAMEDAKIKGIAFTTSPGRMYPNGTFASEFIG
LASLTEDKKTGVKSLVGKTGLEASFDKILSGQDGVITYQKDRNGTTLLGT
GKTVKKAIDGKDIYTTLSEPIQTFLETQMDVFQAKSNGQLASATLVNAKT
GEILATTQRPTYNADTLKGLENTNYKWYSALHQGNFEPGSTMKVMTLAAA
IDDKVFNPNETFSNANGLTIADATIQDWSINEGISTGQYMNYAQGFAFSS
NVGMTKLEQKMGNAKWMNYLTKFRFGFPTRFGLKDEDAGIFPSDNIVTQA
MSAFGQGISVTQIQMLRAFTAISNNGEMLEPQFISQIYDPNTASFRTANK
EIVGKPVSKKAASETRQYMIGVGTDPEFGTLYSKTFGPIIKVGDLPVAVK
SGTAQIGSEDGSGYQDGGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHFG
PLFWQDVVNPVLEEAYLMQDTLTKPVVSDANRQTTYKLPNFVGKNPGETS
SELRRNLVQPVVLGTGSKIKKVSHQPGQTLTENQQVLILSDRFVEVPDMY
GWTKSNVKTFAKWTGIDISFKGTDSGRVMKQSVDVGKSLKKIKKMTITLG
D
>SPy0786 rgpAc, conserved hypothetical protein-possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide
MQDVFIIGSRGLPAKYGGFETFVEELISHQSSKNIRYHVACLSDTKHKVH
FDYKGADCFYLNPPKLGPARVIAYDMMAITYALSYSDQHQIQNPIFYVLG
NTVGAFIAPFVKQIHNRGGRFFINPDGLEWKRSKWSRPVQAYLKFSEKQM
TRQADLVISDNIGIDRYLKQVYPWSKTCFIAYGTQTQPSRLATADSKVRA
YFQTFDIREKDYYLILGRFVPENNYETAIKEFMASSTKRDLVIICNHEGN
AYFKQLLAETECDKDPRIKFVGTLYDKELLAYIREQAYAYIHGHEVGGTN
PGLLEALAHTNLNLVLGVDFNQSVAKSAALYWTKQKGQLAELINQVDAGF
DSDHLGKEAKAIIQEHYTWEKIVGEYEALFLNEH
>SPy0787 rgpBc, putative rhamnosyltransferase-possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide
MNINILLSTYNGERFLAEQIQSIQRQTVNDWTLLIRDDGSTDGTQDIIRT
FVKEDKRIQWINEGQTENLGVIKNFYTLLKHQKADVYFFSDQDDIWLDNK
LEVTLLEAQKHEMTAPLLVYTDLKVVTQHLAVCHDSMIKTQSGHANTSLL
QELTENTVTGGTMMITHALAEEWTTCDGLLMHDWYLALLASAIGKLVYLD
IPTELYRQHDANVLGARTWSKRMKNWLTPHHLVNKYWWLITSSQKQAQLL
LDLPLKPNDHELVTAYVSLLDMPFTKRLATLKRYGFRKNRIFHTFIFRSL
VVTLFGYRRK
>SPy0789 rgpCc, putative ABC-transporter (permease protein)-possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide
MVKTDFKLRYQGSAIGYLWSILKPLMMFTIMYLVFIRFLRLGGNVPHFPV
ALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKHIIVFSAVLGALI
NFLINLVVVLIFALINGVTISGYAYLSLFLFIELVVLVLGIALLLSNVFV
YYRDLAQVWEVLLQAGMYATPIIYPITFVLDSHPLAAKLLMLNPVAQMIQ
DFRYLLIDRANVTIWQMSTNWFYIVIPYLVPFVILFIGIFVFKKNADRFA
EII
>SPy0790 rgpDc, ABC-transporter (ATP-binding protein)-possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide
MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQHVLKDI
NFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVDGKMVSFIEL
GVGFNPELTGRENVYMNGAMLGFTKDEVDDMYNDIVDFAELHHFMNQKLK
NYSSGMQVRLAFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKDS
GKTTILVTHDMGAVKKYCNRAVLIEDGLVKAYGEPFDVANQYSVDNTETA
EDAMNAEKISVSDIAKDLKVSLISNPRITPNDTITFEVSYEVLKDDFTYI
AFSLTDIDRNIWVYNDNSLDYPTQGIGRKCISYQCQLSQLNDIKLKLEVT
VRDKNGQMLLFSTAEQSPQIVIQRNDIDQDDLSALDSASGLYQRNGKWVF
H
>SPy0791 rgpEc, putative glycosyltransferase-possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide
MYKVSIICTNYNKAPWISDALDSFLSQVTDFEVEIIVIDDASTDDSREIL
KSYQKKSSGKIKLLFNETNIGITKTWIKACLYAKGKYIARCDGDDYWTDS
FKLQKQVDVLEASKRSRWCNTDFDFVNSQGDLLYANAFSSGHTPLTDTYE
KVLALKGMTMASTWLVDADLMRQVNQKINVDTPDDTFDIQLELFQLTQLT
YIKDSTTIYRMTTDSDSRPTDTPKMIYRIQKLLDTQLNYLKKYNQVDTKE
VSELLLQQDAKQEIRIHELSCFIQELQQTIVDKTKQQETREVELQNVIEE
QKNQLSELRQQYHAIINSRQWKYTSKLIAFIRRKK
>SPy0792 rgpFc, conserved hypothetical protein-possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide
MNRILLYVHFNKYNKISAHVYYQLEQMRSLFSKIVFISNSKVSHEDLKRL
KNHCLIDEFLQRKNKGFDFSAWHDGLIIMGFDKLEEFDSLTIMNDTCFGP
IWEMAPYFENFEEKETVDFWGITNNRGTKAFKEHVQSYFMTFKNQVIQNK
VFQQFWQSIIEYENVQEVIQHYETQLTSILLNEGFSYQTVFDTRKAESSF
MPHPDFSYYNPTAILKHHVPFIKVKAIDANQHIAPYLLNLIRETTNYPID
LIVSHMSQISLPDTKYLLSQKYLNCQRLAKQTCQKVAVHLHVFYVDLLDE
FLTAFENWNFHYDLFITTDSDIKRKEIKEILQRKGKTADIRVTGNRGRDI
YPMLLLKDKLSQYDYIGHFHTKKSKEADFWAGESWRKELIDMLVKPADSI
LSAFETDDIGIIIADIPSFFRFNKIVNAWNEHLIAQEMMSLWRKMDVKKQ
IDFQAMDTFVMSYGTFVWFKYDALKSLFDLELTQNDIPSEPLPQNSILHA
IERLLVYIAWGDSYDFRIVKNPYELTPFIDNKLLNLREDEGAHTYVNFNQ
MGGIKGALKYIIVGPAKAMKYIFLRLMEKLK
>SPy0282 rgpG, possibly involved in regulation of genetic competence
MFSFTIDYVLVLIGALLMSLFLTPLVRFLAFRVGAVDNPNARRVNKVPMP
TSGGLAIFMSFLVASLGLIPIASKGAMFFGQTYFSYILPVVIGATVITLT
GFLDDLYELSPKLKMFGILIGAVIVWAFTDFKFDSFKIPFGGPLLVFGPF
LTLFLTVLWIVSITNAINLIDGLDGLVSGVSIISLVTMAIVSYFFLPQKD
FFLTLTILVLISAIAGFFPYNYHPAMIYLGDTGALFIGFMIGVLSLQGLK
NSTAVAVVTPVIILGVPIMDTIVAIIRRSLSGQKFYEPDKMHLHHRLLSM
GFTHRGAVLVVYGITMLFSLISLLLNVSSRIGGVLLMLGLLFGLEVFIEG
LEIWGEKRTPLFNLLKFIGNSDYRQAMLLKWKEKKDLKH
>SPy0784 rmlD, putative dTDP-4-keto-L-rhamnose reductase
MILITGSNGQLGTELRYLLDERGVDYVAVDVAEMDITNEDKVEAVFAQVK
PTLVYHCAAYTAVDAAEDEGKALNEAINVTGSENIAKACGKYGATLVYIS
TDYVFDGNKPVGQEWVETDHPDPKTEYGRTKRLGELAVERYAEHFYIIRT
AWVFGNYGKNFVFTMEQLAENHSRLTVVNDQHGRPTWTRTLAEFMCYLTE
NQKAFGYYHLSNDAKEDTTWYDFAKEILKDKAVEVVPVDSSAFPAKAKRP
LNSTMNLDKAKATGFVIPTWQEALKAFYQQGLKK
>SPy2016 sic, inhibitor of complement-mediated lysis
MNIRNKIENSKTLLFTSLVAVALLGATQPVSAETYTSRNFDWSGDDWSGD
DWPEDDWSGDGLSKYDRSGVGLSQYGWSKYGWSSDKEEWPEDWPEDDWSS
DKKDETEDKTRPPYGEALGTGYEKRDDWGGPGTVATDPYTPPYGGALGTG
YEKRDDWGGPGTVATDPYTPPYGGALGTGYEKRDDWRGPGHIPKPENEQS
PNPLHIPEPPQIEWPQWNGFDGLSFGPSDWGQSEDTPPSEPRVPEKPQHT
PQKNPQESDFDRGFSAGLKAKNSGRGIDFEGFQYGGWSDEYKKGYMQAFG
TPYTPSAT