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# Anaplasma phagocytophilum HZ, HZ

>APH_0693 5-formyltetrahydrofolate cyclo-ligase family protein
MDHLEEKVRLRKEYRKLRKAVTTVADAAQMLLQNTISILSFGNHDIVSGY
IPIDGEIDVLPLMNFISKTSVVLVPEVKKDSRMLTFRRWFSGINELGEAL
SPNILLIPLVAFDRRLYRLGFGGGYYDYTIEHLKRRGQCKCVGIAYDLQL
CANLPVCEHDQKLDLVITEKGIYS
>APH_0441 hypothetical protein
MLFFYISASSVSYMLRFVLSVVVLLILSSCGGKYAFEMSRNYAPPYNPGG
DYFDDDESFAQSYEIYEKRREDALREQESMKKRNRGRDLQQKSGRRQISD
EEKGRIINELQRYGVMYNAGERRKGGMVNSEGIDLSRVRGARFIDVDLNK
SGVISGKEERVDESILVKTKEGELLDAEEQSSMLSGGLPGDSADEEHEEF
EVNIDCDCGDDCDCPTGAHKSHGGHKKLSHPVEVEEEQSPALDVISSELP
KDDIAEDQEGIGVKGGCNAGDDSDCPTGAHKSHGGHKKLSHPVEVKEEQR
PALDVISSELPKDDIAEDQEGIKVDCDCGDDCDCPTGAHKSHGGHKKLSH
PVEVKEEQRPALDVISSELPKDDIAEDQEGIGVKGGCNAGDDCPSDELNL
EHGNKEVAVYGEEGASSKDEDNVAEYGSVGDVGADRDDVAEGNDIYPWWE
EYDVVEGFGAFDDSSDGEGYYSESSPVFGEEERAEEDFDVYQDPVEVDDE
GVADSSEDLEADSGADSVTDWEEEGDYLPNDGDVTTSSSAGKGAADDLSV
DDSTFLDEGEEGGYKGIDKDSDGYRIPMSLPDSRSRYYDLGDFVSLR
>APH_1297 flavoprotein
MDILLLITGSVAAYKALEVIRELRRRKYNLRCVLSKAGEQFITPLSVSAL
SDANTYTESDSFSPQECMKHISLSRGTDLILVVPASADIMGKAAHGICDD
LPTTILMAANVPVIMAPAMNTVMWQSPAMQRNLNTLKQDKVFIIEPETGI
LACGEEGPGKMAKVEDIVAFVEKFQKC
>APH_0791 putative nicotinate (nicotinamide) nucleotide adenylyltransferase
MIVGIFGGTFDPPHEGHVYIAQKLRKLLRLREVWWVVTSRNYLKSSSKYD
LEKRKDLVQEVVLKLQGMRVITMDSPRGYEVVQYCKNKYPSFKFIWIAGS
DNMASIHRWYRWRDFCEMVPIVFLERAVSTYKVLKRPFASVVPRVNFSAD
NVCNISRGWSIIRARACDMSSTKIRNKL
>APH_0246 DNA / pantothenate metabolism flavoprotein family protein
MQRICKTECAGLYLSQFLIEIICVVSVLITAGSTREYIDPVRYISSGSSG
KQGYALAECMGKMGWDVKLVSCPVALAPRQDLYQTYHVNTSADMLNTCLS
LLPVDVAILTAAITDWVPYRCKHKLKKHAVDRIDMLHSPDIAKCISMNKD
RPKLVIGFCLESENLIESAKNKLAYKGCDWIIANHYYVNEHEPVMHSNYN
QVSIVTRDSVRPFQMMTKVEVAKLLTEEIIDYLNRLDIP
>APH_0058 S-adenosylmethionine synthetase, truncation
MPLSEAATIAGEVSGVIVEEEKVDGVVRKTLREIGYEKEGFHWREVKVRI
MLQEQSHDIMLGVNRGRKKKGAGDQGVMYGYAINETESYMPSPIFYSHRV
LKNLSDAVKQGSITGIGPDAKTEITLQYVDHKPVKVLRAVLSVQHDESRT
QQDVRDLVYPYFVSSIPEGWMCKEENFLVNPTGRFVVGGPVGDTGITGRK
IMVDTYGGHIPHGGGAFSGKDPSKVDRSAAYMARYIAKNVVHAGLASECL
VQMSYAIGVPAPLTFAINTFGTSVVDVKEIERCIISNIDLSVSGICEKLS
LYEQIYSPTSCYGHFGRTHENSFSWEKLDLSLILNREFSCN
>APH_0876 biotin--acetyl-CoA-carboxylase ligase
MKPFVIHRRSISQSTNLDAMELAEQGADSGTVIVADEQSSGVGRRGRQWY
SPKGNLYFSIVLKEHLHVPTLSFACALSVGISLEQIFSQHIENSKIPTLK
YKWPNDVFVDNKKISGVLLQSKVQGHSIPWIVCGVGVNILHHPEYATSIS
SYIPDLKLTNIELLDVVLENLAKLLDIYSASGFAPLRSLWLKKAHALNSH
VCITTSDGITHEGTFTDIGLDGSIVLKSGEDTLKLDYGSML
>APH_0070 thiamin biosynthesis ThiG
MWDVYGVQLRSRLLMGSAQFASPEILQRSLHNSGAEVVTVSLSRQMPEIG
GGQDYWDIIKQSKCRVLPNTAGCYTVKDAVLMAQMAREIFNTTWIKLEII
GDDYTLHPDVVALCEAAKELITQGFDVFPYCTDDLTVCRRLIDCGCRVIM
PGISPIGSGLGVLNMHGLRLLRNRYKDIVLIVDAGIGRPSDASVVMEQGI
DGVLLNSAVARAIDPSKMASAFRYAIECGRLGYEAGIINKRDLAVASTNL
VDTPFWHRNKS
>APH_0979 8-amino-7-oxononanoate synthase, truncation
MVFSSGYTTNIGSISALVGRHDMILADKFIHASSLDGARLSGATIYRFTH
NNVDHCMQLISKYRELHDNCLILLENIYGVDGDLAPVDEFIQLAKEWNAW
VIVDTAHGFGMLSSLQADIYVGTLSKAMGALGGFVCSSKITIEYLLNKSR
SFIYTTALPPAIIAAASASIDLFKSYAEVPMRLAKEFCKIMELPEPQSHI
VPLIMEDVRSVILAEQALAERGILVSAIRPPTAPTPRLRLTFTAAHKLID
VHRLCNALKACVVLTEAGNWRVL
>APH_0648 conserved hypothetical protein
MSVCFRSFVLLLSTVVCVINTTCMAASVVFQQQAQQVVVGFLQTAEETYP
EELTFSHNIYELFTGLGAKVIRLDYNKVLDFELIRQSALEEAHGDISKIH
DLEARMIKEGILSFLKENEIDRVFIPGNYYNVDAEPYAPTPNRQLVTAAI
AEIVHENPAIKLMGVCGGLQGVMHAMGIKVIRVYKLLGSHESAAVHAVSM
PDPHHKDVVLHRLRIVPGSRLASIVSKHVEPDTNGWYSLFFPDAHGGVVS
NDPENVKKLEDLGYKIVGFSDDGIIEAVEDVHGNILFQDHPEALAINMLR
GHVYPDADITTSSQQDLRYKAALSAISIIEDFLYRQ
>APH_0586 thiamine biosynthesis protein ThiC, truncation
MHMNISEIYPSSNKIYINCTLYPDVKVGMRQINIRNSSQRFLLYDTAGPY
TDCDIKVNLTEGISSIRRDWIARRNDTYPIRKAKTNSDARGVKALSGDDR
VILKGIAGGAPVTQLFYAKKGIITPEMEYVAVRENALLEQAEAIPGLLLP
TKTRKITPEFVREEVACV
>APH_0545 heme/FAD-binding domain protein
MLTLTPQDLYSIDGLRKIDELFQEEVKRHCPNLLERLIEARCTGEGDAEL
IIELAHLLERFITKIFHIEEELKAYQKLHEEFLDLYKCKRNFVQRYAIKK
FPDRESLTLNVEEALLSILEVANIPVDENVFASKVNAWMEDKEQYEQQLD
IAAQYAAHMVHSGSKSILFQVPQKYEAENLIPVDRACFDNNIDVTVAKSC
LIKERTGFNIANPPSANKALNEVHYCILCHKQKRDSCSKGMVDKQDIVKA
SPLQVLMTGCPLKVKISETNLLKSQGLVLSPLAVIAVDNPMCALTGHRIC
NDCSRACIYQKQQPVDVPSIESYILDSVLNLPYGFEIYSLFTRWNPLSFT
NILPKEPTDKNVLVVGLGPAGIGIAHYLLNEGHNVVAIDGLKIDPLPEHL
SGVTEHNKKTSFTLIKDAKTELFEHLDYRLAYGFGGVSEYGITARWSKNY
LKIARILLERRANFMMHGGVRLGSTLSAHDAFTIGFHHIALATGAGAPKI
PMLKNMLVKGVMTASSFLMALHLGNAAHKDSIANLQIRLPAIVIGGGLTA
VDAATELLAYYPVQVEKFLQRYETLLEECATNTSEICWSDEEREIFNEFI
EHARQIRCEKELAIAEQRSPNILKLLQKWGGVTIVYRGSFSSSTAYRLNS
EELEHAMSEGIYFAENLQLDEIIVDKHNSAAGLQVHDIDNAKKYIAAKSI
VVAIGTNENSITLEECKTYNSHSASSIDTQENMPLDENNFYISAEKTISA
FGDIHPYYKGSVVKALASAKSGYTSITKALEDFPKCSDSEGFFSDINRLF
SSQIVKVISLTDNIVEIVVRSPLAAANFQPGQFYRLQNLGRNNHPNLEME
CLAITGAYVDKENGTVSVVVLDVGGSSRLCKHLQPGQSISLMGPTGSPTH
IPHNENVMLIGGGVGNAVLFSIGEAMLTQQCKVLFFAGFKSESSIFGRQQ
IEYASDVAVWCCETGKFQPQRPDDKFFYGNILAAIEAYYNDPQTKITLNS
IDRIIMVGSSGMMAALQRAISGKFKHMFKSNIKIVASINSPMQCMMKEIC
GQCIQKHVDPLTGEERFVYSCVNQDQCANKVDFDFLQDRLKQNSVLEKCT
SIWVSHCLKQAFNTNQSRKDTHD
>APH_0814 GTP cyclohydrolase I, internal deletion
MAEVTQCGRVCPTIEEAEEAVRVIIRWMGDDPNREGLLKTPRRVLDYYKK
SCSGYAPELLSHYSILPYDGSSSEMVLVKNIGFSSNCEHHLSPICGVAHI
AYMPKEKILDPHGVAVLLEAEHWCVECSNRDTASRDERLNVQTSQMLGVF
EERCDLRNEFFLRIKM
>APH_0354 conserved hypothetical protein
MLLLTRAMCDSVKSRDALIALGFDVFIEPMFEVRYLAAEITGLEGYEVVL
ATSRHGIIGMAQATDNRSIPIVTVGDSSMKHALSLGFQNVKTVSGTAEDL
LHYLRTKSYSSKVLYIRGTNISHDLSKMARNFGITVEELILYETIRSTEL
SPECCYLLSKRKISGVLFYSMETAKIFMNLVEKKYKECLATVAAYTISSR
VCDALNTCKWKGVLVSESPTEESLFRLLLK
>APH_0856 putative biotin--acetyl-CoA-carboxylase ligase, truncation
MEDMFQSAIRRRKIFKGNRYSVTFYSEGGRCDNDLCGVIISHLETVNILH
HPEYATSISSYIPDLKLTNIELLDVVLENLAKLLDIYSASGFAPLRSLWL
KKAHALNSHVCITTSDGITHEGTFTDIGLDGSIVLKSGEDTLKLDYGSML
>APH_1140 hypothetical protein
MDCPALSSEARVTSGNYWLTALTPISGAITASAAIDLEDHNLYTFRSAIT
RNKRSAFMLA
>APH_0911 Coq7 family protein
MIRVNHAGEYAAVCIYHGQEMALRGKAEAESIREMQQHELVHFRYFDNAI
KERRVRPTVFLPIWHVAAVSLGYIAAMMGKEAAMACTEAVEEVICGHYYE
QAGQLERSDSEHELRDAIVRFREEECEHMEIAAHNGAERALGYKAISCAV
KTACRLAIAISKVL
>APH_0009 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family
MVDIVSNYYDVVILGGGINGVLCAIGLSHKDISVLVVEERDAILDGNQGR
VYAFSKRSKEILENFSVWNDEIRSSPIDHIMIYDGNSCSSVHYDRVLVDD
QPMGYVVEASEIAKFMHQKLNFDVITSSSCKLFTVKDGFAEIYLSCGKKI
YTKLVVCAEGKNSRFRNSLSLKTINYAFEQGFIVCNINHSKHHRNTAIEH
FCTNGPFAILPMYGGYSSSIVWTEKYEMAQLIQNLPIEEFTKLLQEKCSD
FLGKIEVNSKINCYKTSMSLLKKIFINRAIIIGDAAHAIHPVAGQGLNLG
IRDVGILVEIIEKYHKLGSDIGQRFILQEIDNRRLLDNVSMSFVCTGINS
IFSNDSAILKVARRATMSVVEMSPTLKKILMSHAMGISSICK
>APH_0482 bioA, adenosylmethionine-8-amino-7-oxononanoateaminotr ansferase
MYEHAHWFQEEKVLFPYSSAVPAVAPMRVVSGQGSYLELEDGKRLLDGIS
SWWSVCHGYSHPYIVGKMQEQLAKLSHVMFCRDLIHEGAYVLASRIAKLM
PPGLDRVFFADSGSMAVEVALKLAVQYWYSMGKREKHSFIYFKNSYHGDS
MGCISISDPAAIHGDSFTRYCPKQYLLDIPASEEDVVLLQQKIESIADKV
AAIIVEPLLQAAGGMVIYPPHVLSTLRKIAKENEILFIADEVATGFYRLG
TSFACEQASIQPDIMVIGKALSGGTCPLSAAVVSSNISELFISGGETFMH
GNTFMAHPLSCAAANASLDLFAGESYTQKVSGIERILKAELEELHALDYV
CNVRIKGAMAAFNIKNECVEKLKNGMTQKLLDLGIWIRPIKTVMYVMPPL
TIAEDELLALLSALKTLVYECRR
>APH_0218 bioB, biotin synthase
MIRNNWTLEETLELFGLPFNDLLFKAHMVHREYFRHNEVQVCALANIKAG
GCPENCCYCSQSAHNKTGLTKKGLSSVEEVRTAARRAKDVGVHRFCFAAA
WRNLHDRDVDRICEFVKAIKEEGLESCASLGMLKLEQAQKLKEAGLDFYN
HNVDTSRAYYHNIVTTRTYDERLDTINNVQEAGINVCCGGILGMGESTED
RAQMLLTLANLKQHPRSVPINRLVAFKGTPLEGAKKVNSVDFVRTIAVAR
IMMPASYVRLAAGRSDMTEEMHALCFFAGANSIFYGEQLLTTENATPEFD
QNLLSRLGVVATPSGAHESCAC
>APH_1228 bioD, dethiobiotin synthetase
MPAYFITSTGTDVGKTFVTTALCWHFRRIGHNVQAIKPVITGWNSATEGE
SDTVKIIQSLECTVSEQSISRVSPWRFEAPRAPNVAADMSGAHLDYEEIL
RFCRKSSQTLDSYTFIEGVGGVMSPITENKSCLELIHDLGIDVVLVIGSY
LGSISHTLTAMKVLQGLRIHVILSEKEEENPCARDVVEYVNQYYNCTVYI
QEHVSRNLRAPWTHTSPEIAHFLLR
>APH_1016 bioF, 8-amino-7-oxononanoate synthase
MLKDILRERLEVIESNGLLRKLKQSTIQSSIAGRKIQNDAGNELTSFSCN
DYMGLSTHDVVKQAAIDAINLYGMGARASRLTTGNHPLYAEIEAKLASLY
GTEAALVFSSGYTTNIGSISALVGRHDMILADKFIHASSLDGARLSGATI
YRFTHNNVDHCMQLISKYRELHDNCLILLENIYGVDGDLAPVDEFIQLAK
EWNAWVIVDTAHGFGMLSSLQADIYVGTLSKAMGALGGFVCSSKITIEYL
LNKSRSFIYTTALPPAIIAAASASIDLFKSYAEVPMRLAKEFCKIMELPE
PQSHIVPLIMEDVRSVILAEQALAERGILVSAIRPPTAPTPRLRLTFTAA
HKLIDVHRLCNALKACVVLTEAGNWRVL
>APH_0650 coaD, pantetheine-phosphate adenylyltransferase
MTKRLGIYPGTFDPITFGHIDIIKRACTLVDELVIGVARSVQKSTIFSAE
LRAEMIQREMHVLECKSVVKVEVFDGLLTAFAKQKKALMIIRGLRAVTDF
DYEFQMSWINYKLTPGIETVFLPAAEETQFISSSFVKEVARLGGDVSVFV
PHNVHEHLRDFYNNSSAK
>APH_0780 coaE, dephospho-CoA kinase
MIIFGLSGGVASGKTQVARLFSQFGKARVFNADREVHKMYEHDASIIGLV
REYFPDSIHDGCVSRKELLKHFVEYGSKWQMLQAALYSELLIRQNRFITE
SRIRKARYVILDIPMILEAGYWRSCDFIVWVRVSKAIQVRRLRERGISQE
GIKCLLSRQVQAEKRRNFADFSINTCGSIRDTALGVLAILNNSRVNAQRD
IRFHSQRLCILPRRNGLGRLPSVL
>APH_0628 folB, dihydroneopterin aldolase
MVFQLNIEDLVVFMCIGVYNWERIIKQKVYVSINVTYSSEQGGEFLDYDT
FSQRIIELLTAKDYLLLEDAISDVISFIVLEHETTLACEVKIYKPVVSFL
RDSKSISISAIWNKDR
>APH_0747 folC, folylpolyglutamate synthase
MVYMPHWPKVLEFKPEGLTLDRMREILCRIGNPENNLPPVVHVAGTNGKG
STIAFLSSILQAAGMRVHVYTSPHLLEFNERIVLNGSKISDNHLHEILEE
CRSKCDGMTVTFFEATTAAALLAFSRVHADIVLLEVGMGGRLDATNVVMP
ILTIITSISYDHTCFLGDTVELIAGEKAGILKEGVSCVLAPQKYDAARRT
IEYHAAVNHAPIYRGGIEWSCTKDADGMVFRSSEEYNFPLPALQGDHQID
NAGTAIAACSVLSGKFGYEISHEDIEAGLVNAVWPARLERIASGSLYNML
PKCWKLFLDGAHNVAGAEALRDWITAYMKHEDVYLIVGMTKDRDSKAFLE
PLKQHIRFLCTVCVKAEYRAQSAEDILKCALELDIPASAEEDIRASIQKI
IDIGDRVRSATILVCGSLFLAGDLLRESL
>APH_0175 folD, methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
MGIYENNIIDGKAAAADLLGRLKVVMEGLKEEHGLFPSLVVIIVGDDPAS
RLYVGNKQRKAEELGINSKTIALPYETTQEELLGIIQELNEDENVHGILV
QLPLPKHIDKILIINAIDPEKDVDGFHNANAGKLLTGEMDCMVPCTPQGC
IYLIKKVMPVLSSKRAVVIGRSNIVGKPVALLLMYENCTVSILHSATANI
EEHCRDAEIIIAAVGKARMVKSEWVSPGAVVIDVGINLITSESKNRFVGD
VDFESVRDKVAAITPVPGGVGPMTIAFLLVNTVLGACRQKGIKQYKNIKS
SVLQ
>APH_0706 folE, GTP cyclohydrolase I
MAEVTQCGRVCPTIEEAEEAVRVIIRWMGDDPNREGLLKTPRRVLDYYKK
SCSGYAPELLSHYSILPYDGSSSEMVLVKNIGFSSNCEHHLSPICGVAHI
AYMPKEKILGIGSIAHIVGCFSKRLQLQERLTNQVAEYLEKILDPHGVAV
LLEAEHWCVECSNRDTASRDERLNVQTSQMLGVFEERCDLRNEFFLRIKM
YK
>APH_0212 folK, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase
MVKQIYQPNKSAMVVLALGSNIGDRMSALKEAIKLIPLHNRLYSSVYESC
ALLPDNAPFCWNMPFLNMVIAGYTHFSPEDLLQSIKQIESQLGRCSLGHW
SPRSIDIDIILWEGVTVEDKALTIPHKEMHKRDFVLVPTCDICPRFPHPI
LKETVESILLNKQDINLVKKYQAIHL
>APH_0254 folP, dihydropteroate synthase
MQHSAVTTKIVGILNVTPNSFSDGGKFLEANAAIRHATDLIEHGADVIDV
GAESTAPGVSPITQEEEWSRLKEVLPEIIRIAHNAHVEVSIDTRNAKTAE
LALKLGVDYINDQGGLLDPDMPAIAAASSAKIIIMHHFGLPVSQDRSYVG
QPEQLLNEIIEWLCSRVDTLIAQGVVRERIILDPGLGFGKLPEYSWYIAK
NIGKLKKLGFPVCVGHSRKSMFSLIPVELSERDVPTAMLSTFLAQQQVDF
LRVHDVKLTGISIKIANLLV
>APH_0193 gshB, glutathione synthetase
MLKVAFQMDADVVVGKDLTVQFIQESKRRGHDVFFYQPRDLSFSRGEVVA
TAYSVDIGENSLHLRDRVRLSLEGLDILFIRQNPPFDMRYITNTYLLERL
AGVLFVNDPKAIRDFPEKLLPLSFPEFIPPTLITESVQEACEFYREYGDV
VIKPLYSFGGDGVIRICGNVDIAVIFDVMVARYGTQVVIQQIIPSVEDDK
RVVLLNGEPIGAIKRRVISSGEIRTNLRVGAVPEMTELSERDREICRVVG
DKLTAAGIIFAGIDILGGYLLEVNVTSPCGILEINQVYGTTLEKECWDQF
EGMLA
>APH_1243 hemA, 5-aminolevulinic acid synthase
MIDYEEVFRERINGIKEEGRYREFTGFRRVPGRFPYAIECQTERVVTLWC
SNDYLGMSQHESVLSAARNLNVNVGAGGTRNISGTTEEVIELERSLADLH
NKPAALAFVCGYVANQTSISTILATIPDVVVFSDEKNHSSMIEGIRAGNR
VKHIFRHNDVEHLESLLKAAGASPKIILFESVYSMDGDIAPIKEICDLAS
KYNAITYLDEVHAVGLYGARGGGISEMEGLADRISVIQGTLSKAFGVMGG
YVAASKSLVDVIRSFAPGFIFTTAISPLIAASARASVEHLKNSNIEREKH
REVIAKVKSALLQAGIEFLMTDTHIIPVIIGDATICKQVSQALLRDHGIY
IQSINYPTVPLGTERLRITPTPYHTDEMIDHLVKGLQEVFSRFSVPAGRS
YAYFEALGKLKESR
>APH_0851 hemB, delta-aminolevulinic acid dehydratase
MQFPKTRLRRKRAHGWMRAMVRETVLHPKDLILPIFIHEKDEASVVLEGL
DCMRRVSMTEAANLAQEAHSLGISAVILFPADCEKSPDAAEACNPENLVC
RTIRLIKESVPDIGVMADVALDPYTTSGHDGIVVNEVVDNDATLDVLCKQ
AVVLAAAGCDVVAPSEMMDGRVGVIREFLDNCSFSHVSILSYAAKFCSHL
HRPFRVVVGSRTASQSVDKSTYHMDPANAREALLEAQLDIDEGADMILVK
PGIFYLDVLSSISNTFDIPVLTYQVSGEYAMLKAAALQGWLDYEQCMHEA
LLSMKRAGARNIITYAALEVARKLRGAGDV
>APH_0746 hemC, porphobilinogen deaminase
MGIVMVIRIGTRGSLLAMQQARIVKTAIETNYAELSTRIITIKTSGDMNT
HVPLYDIGGKGLFIKEIEEALLDNIIDVAVHSAKDVPGIYSEDLDIPCIL
PRASALDAFLSSKYDSIASLPLNAKIGTSSVRRKVQLLTMRPDLEIIPMR
GNVETRISKMQMGECDGIVLAEAGLYRVSKDNLISEVLQPEVMLGAVGQG
AICVQCRRYDRRILEILKKLNCHKSYTTVSAERSFMRAVDGSCNTPLAAM
AKYIDMDILTMKCMLADDARNMVFTERVFAEQNAESAGYEMGTLLKNELH
LHRL
>APH_0020 hemE, uroporphyrinogen decarboxylase
MKIIIYNKKTITVLREILTTRRSTQRLPIWFMRQAGRYLPEYQKVMAHVQ
DFLEACYTPEIVEEVTLQPIQRFDLDAAIIFSDIMTVPDALGFEVVFKRG
YGPQINAKTRREVTLEWSLEKVSPVLESIKRVRKSLSPNKSLIGFAGSPW
TVATYILEQEKKITDIFALHRSGDNSVAKLIDEIVSFTTVYLKKQVEYGV
DILQLFDSNASGLPVDLFETFIVEPTQRIVKELRKHHPSIPIIGFPKGAG
VLYTHYALTTGISAVSVDYSIPSQWIKNNISGVVQGNLDPFLLAYDVEGA
LKCAGEIIADLRDKPLIFNLGHGIIPPTPVDNVYRLVDFVRSF
>APH_0423 hemF, coproporphyrinogen III oxidase, aerobic
MDEKKDLVTEWFAVLRDKIVSAFLAVEADFSDNAPTIKKRKWEREGGGGG
ESVIILGSVFEKAGVNFSIVHGKLKSDFAAEIPGARESNGEFWASGVSIV
AHMCSPFVPAIHMNTRFICTSKSWFGGGIDLTPVYHNDDDTIFFHDALKA
MCNKFDAHYYDQFKKNCDEYFYLPHRKEPRGVGGIFYDYLQTGFEKDFAF
TRAVGECFLEVYPAIVRRNMHKEWSEEERDYQLISRGRYVEFNLLYDRGT
RFGLMTDGNSDAIMMSMPPLAKWV
>APH_0263 hemH, ferrochelatase
MSRKIAVVLFNLGGPASLREVESFLFNMFNDSHIVSAPRPFRYFLAKAIS
KLRARSSREIYTLMGGKSIVEQETAKQAIALEELLNKNAETGCSYKVFTC
MRYSAPNALTVLGDIDEYKPCKVVLLPMYPQYSSATTQSSIEDWFSTSHK
AGYSFWTDIIWDYHSDEHFIAAHCKLISEAYEKALALNARARILFSAHSL
PVSFIEKGDPYKQQLRQTVLSILQNMGLQSIDNTLCYQSKLGPVRWLEPS
TKSELLRACNDNVSVVLVPIAFVSENSETLVELDIEYKALVGEKKFIRVP
TLGTDPKFIECLCNLVLAKQ
>APH_0329 ispA, geranyltranstransferase
MMRCHIKERVKDFSNLVGKELTKLIETQVTGGPAAGLVDAIGYCILPPGK
CLRAFLASSVAQTFGVSIERTLPLCLAIEVLHSYSLVHDDLPSMDNAPTR
RGKNSCHIEHGEALALLTGDALLTLTFELLSSMDESCTVKCAIIRVISDA
CGHRGMVAGQALDMGNLEPSLEAVKQIHKLKTARLFSAACESGAILAEVS
TANQQALASYGETLGCAFQAKDDLCDINEDDSCLNIARILGREKTLEYID
YLLHQSEEYLERIDEDTAVLKELVAFIRNL
>APH_1247 ispB, octaprenyl-diphosphate synthase
MKLLVASELQEMESLIVKQRHSEVQLIADIIQHLILSGGKRTRPVMLLAA
CGMLGCTDARRIVVAAAIEFLHSATLLHDDVVDKSDMRRGVETANSIWGN
KASILVGDFLFATAFQWIVSCNSIQLLSVLSNTASIIVSGEMQQLVHSSS
LDISRTKYLEIISSKTAVLFSAACESAAVLHDVGTLQRNALRDWGFNFGI
VFQILDDILDYTANQNELGKRTYNDIVSGKVTLPLIIAYEGASEKDRIGL
RGALSRERPDPDLAFSYIMAQNAIEKSVGLAKEYIAIAEKQLSHFPDSAY
KQKLLNLLNSAVNRRF
>APH_0367 lipA, lipoic acid synthetase
MNSKPSWLRVKMPGGEVFEEVRDLVKRQRLNTVCEEAACPNIGECWNKRH
ATIMVMGDVCTRACAFCNVKTGVPRALDLGEPERVGEAISKLGLKHVVIT
SVDRDDLPDGGASHFAKCIREIRKRDPNVTIEILTPDFQGKPGAVDVIAS
ARPDVYNHNLETVPRLYARVRPRAKYFNSLQLLQQVKDKTQGVFTKSGLM
LGLGEQKEEVYQVMDDLRCAGVDFLVLGQYLQPTKDNIDVDRYVTPEEFE
QYKRMAYAKGFSMVASSPLARSSYHAEDDFLRLRALRTARMRVAT
>APH_0243 lipB, lipoate-protein ligase B
MDIEWQISSGLVEYEVAVNAMVSRVDKIVQGSEREMVWLLEHPPVYTAGT
SANSSDLLIDNLFPVIKTTRGGKYSYHGPGQRVVYVMLDLKRRNRCDIRA
YVRDLGVWIVNTLAEFAIDSYFSSENIGVWVQNDMHSEKIAAFGIRLRRW
VTYHGVAINISTDLTHYSGIVPCGILGSGVTSLRALGKEVTFEQFDSALK
KEFYKVFA
>APH_0007 metK, S-adenosylmethionine synthetase
MFHLDRYYNSYFITSESVAHGHPDKVADRISDDILDYFMSINPEAHVAVE
ALVTRDNVIIAGEVSGVIVEEEKVDGVVRKTLREIGYEKEGFHWREVKVR
IMLQEQSHDIMLGVNRGRKKKGAGDQGVMYGYAINETESYMPSPIFYSHR
VLKNLSDAVKQGSITGIGPDAKTEITLQYVDHKPVKVLRAVLSVQHDESR
TQQDVRDLVYPYFVSSIPEGWMCKEENFLVNPTGRFVVGGPVGDTGITGR
KIMVDTYGGHIPHGGGAFSGKDPSKVDRSAAYMARYIAKNVVHAGLASEC
LVQMSYAIGVPAPLTFAINTFGTSVVDVKEIERCIISNIDLSVSGICEKL
SLYEQIYSPTSCYGHFGRTHENSFSWEKLDLSLILNREFSCN
>APH_0026 nadA, quinolinate synthetase complex, A subunit
MLQEHRDLLREIRDIARKKKAVILAHYYQEDEIQEVADFVGDSLDLSQKA
STTDADIIVFCGVFFMAEVAKILNPSKKVILPDLNAGCSLADSCRGEDFK
KFRQAHSDHVSVTYINSSAEVKCYSDIICTSSNAVSIINRIPKEKKILFA
PDRYLGEFLISKTGRDMLLWNGSCIVHERFSEEALVNLMVRHKDAHVVAH
PECPGNLLRHAHCVGSTKNLLQYVKDRPGNKFIVLTEEGIVYQMKKSSPG
STFYVVGAEHSSGCEYCSQCPYMRLNTMEKLYKCIAEELPEVTLDEDIIF
AARRSVNAMMDFSFAREPAVV
>APH_0016 nadC, nicotinate-nucleotide pyrophosphorylase
MFEYIIQRALEEDLGTIGDITTDCIIGDQRIKFEVNAREELIVSGMLFIS
DLANVLHKEDISFYPMEVDGTPVKSGTCLLRGEGSASKILSVERVLLNFI
QRASGISSLTRQFVEIIHGTNAIIRSTRKTCPGLRKFDLYAVHVGGGESF
RTGLFDGVLIKDNHIASCSGISECVHKVRAKLGNVVILVECDTTEQVEES
ILNNVDTVMLDNMSLDNIKKSVSIVNSRAKIEVSGGINLNNVRPIAECGV
DYISVGCITNAVKCKDIGLDVIEQI
>APH_1269 p44-16, P44-16 outer membrane protein
MMSMAIVMAGNDVRAHDDVSALETGGAGYFYVGLDYSPAFSKIRDFSIRE
SNGETKAVYPYLKDGKSVKLESHKFDWNTPDPRIGFKDNMLVAMEGSVGY
GIGGARVELEIGYERFKTKGIRDSGSKEDEADTVYLLAKELAYDVVTGQT
DNLAAALAKTSGKDIAQFANAVKITNSTIDGKVCSGKHAALVTGKGKTYH
EKPGTTEDNSAQCSGLGDGSAGADQKFLSKFVSAVGLSENKNWPTGQAGK
STGGPEVGAPNSNANAVAKDLVALNRDEKTIVAGLLTKTIEGGEVVEIRA
VSSTSVMVNACYDLLSEGLGVVPYACVGLGGNFVGVVDGHITPKLAYRLK
AGLSYQLSPEISAFAGGFYHRVVGDGVYDDLPAQRLVDDTSPAGRTKDTA
IANGFYHRVVGDDVYESRGIKIVGVQHHA
>APH_1287 p44-32, P44-32 outer membrane protein
MMSLAIVMAGNDVRAHDDVSALDTGGAGYFYVGLDYSPAFSKIRDFSIRE
SNGETKAVYPYLKDGKSVKLESHKFDWNTPDPRIGFKDNMLVAMEGSVGY
GIGGARVELEIGYERFKTKGIRDSGSKEDEADTVYLLAKELAYDVVTGQT
DKLTAALAKTSGKDIVQFANAVKITNSTIDGKVCSGKHAALVPNKGKDYD
ADAKESNTNAHKTAQCSGLADSAATGPKSFSGFVGAVKVGEGKNWPTGRA
ASATSNETVVGPTNSNATAVAKDLVALNSDEKTIVAGLLAKTIEGGEVVE
IRAVSSTSVMVNACYDLLSEGLGVVPYACVGLGGNFVGVVDGHITPKLAY
RLKAGLSYQLSPEISAFAGGFYHRVVGDGVYDDLPAQRLVDDTSPAGRTK
DTAIANFSMAYVGGEFGVRFAF
>APH_1008 pdxH, pyridoxamine 5'-phosphate oxidase
MTINKEGLRVDACSGDPMSIFGLWYEEVLRVKSVREPSAMVLATCDSENR
PSARVVLLKRYSDAGFEFYTNLESRKAREIALNPCVSLVFDWRPIYKQVR
VEGIAEFMDASESDAYFASRSRESQIGAWCSRQSMILEDRDVLLSKIELM
EREYEGREIPRPKFWGGIRVVPNVIEFWMDGKHRLHDRRQYSKNIDGTWT
SVYLYP
>APH_0790 pdxJ, pyridoxal phosphate biosynthesis protein PdxJ
MQLGVNVDHVATLRNLRGTTYPSIVELANIAVEHGADFITVHLREDRRHV
RDDDLYALKKHVNVPINLEMAATEEMLAIAKELSPEFVCLVPEKREEVTT
ESGLDTKLLYDTRLFIISELQRHGIKVTLFLDPSEEDIACAKRMNVDKIE
LHVGAYCISRAPQELEMITRAAQLVHEAGMICHAGHGIDYECAAAISKVK
HITAINVGHFLVCEAITQGMGNAVRKMKDIITS
>APH_1314 ribA, GTP cyclohydrolase II
MFGPIGNFFGLGNNLLSRAVNEIRRCAPVILHEDDKYLLVFASELLEEPS
LAVFKSFSDNVYILLTAQRASYVTTNDKLSRVGANTLSLADIRTLMSGLP
EETRSVPVEESLSPLDSLAIDLVKMAKLLPSALVIDMGFGNIEEMYDWCK
CNGILHLAGKALTDYTQEYVLQEVCRSDLYLQDSLKSKIIVYRSKIGEPE
HYAIVIGEPAIENIVVRLHSSCYTGDLLGSLSCDCRSQLLTAVKLLAEQA
GGIILYISQEGRGIGLANKIRAYSLQMQNSLDTVDANRFLGFDDDERIFL
PAAMILRNLGVSSLQLLTNNPHKVQEIGKYGFDVTKTIPFHMEINEYNGN
YIKTKQTRLGHTN
>APH_1332 ribB, 3,4-dihydroxy-2-butanone 4-phosphate synthase
MSFEPSAAVFSSIEEVVRDAAEGKVFVLLDDEERENEGDLVALADRVSPE
AINMMIRYGSGIVCLAFSEYHAKKLGLGLMSRRNANDGCPAFAESIDARH
GITTGVSASDRAATILKAVSDDSSADDIVTPGHVFPIVANPGGVLKRGGH
TEAGVDIAKLAGAAHAAVICELMNPDGTMARLPEIMEFASANGIKVTTIK
KLREYLSSS
>APH_0037 ribD, riboflavin biosynthesis protein RibD
MVPDERFMAMALTLARRGLGNVYPNPAVGCVVIRDGVVVGRGWTVAGGRP
HAEIVALQNAGNRAIGATVYVTLEPCCHDGVTGPCTSALINAGVSRVVIG
VQDPDYRVSGKGISSLEAAGIEVKYGVLQQQAEALNAGFFYSKVLHRPLI
TAKLATTLDGKISFDEGCDRWITNDLTRKWVHKQRAMYDAILVGSNTVVA
DDPMLDCRLPGLEKHSPIRVVVDRSGKLLAHHKIVCTAGTIPTYIVTDND
PQCVFENVKYIKVDGGTEFLENMVRALTAQLGITRLFVEGGGILITELLK
KKLIDRFIWTRANKISGSKGLNSITDIDAQFGQCCKFVKTDTLSFFDDTV
DLFDVKYTQLGSNL
>APH_0106 ribE, riboflavin synthase, alpha subunit
MFNGIVTLIGRVEDIQHDGDTDVIARISVQSEEFLSQIVIGSSIACSGVC
LSVVEKGATHFVTNISKATLDITNLRFWTLGTKVNLEPALRAGAPLDGHM
VQGHVDCIGEIHSITQVAGSHVMEICCDSSTSKYIAKKSSIALDGVSLTV
NSTTPGLFSVNLIPYTWNNTTFQYNTVGDFVNIETDLIARYLEALLAHRT
YGL
>APH_1161 ribF, riboflavin biosynthesis protein RibF
MRLASIASFVCKDICMEVLCERPSAREVVLTFGNFDGVHRGHMHVFSEVV
RLAQEHNLASAALTFSPHTAVFLKKRENFLLSDFERKVQLIESCDIDYLH
VVEFDELFAKMLPEAFIENILVQRCKARHVVVGEDCVFGYRCMGNIDTLR
SYSQSYGYKVMVVDHLSISGKKICSSSSIRKCVESGDIQAANLLLGRCHA
ISGKVMRGRARGRTIGFPTLNLSLEHTIMPCRGVYNARVLIGQEWLLGIA
NIGVRPTFSEVELPILEMHIFDFDEDIYGRKVTVELLDFIRPEQKFQSIE
QLVEQIKRDIAVVKRQKH
>APH_0539 ribH, 6,7-dimethyl-8-ribityllumazine synthase
MGSVMDAKLSALIVVGSFHTEVCGQLVKGAIERIKAYNAAAECEVIEVPG
ALEVPPAISFAVMSDRESYDGFVALGCVLKGYTDHNIHVSNSAFSALSDI
AVQHAVPMGTGIITADTMSLAMERADVNGINIGGRAAAAMLRMLELYRRF
LG
>APH_0600 thiC, thiamine biosynthesis protein ThiC
MHMNISEIYPSSNKIYINCTLYPDVKVGMRQINIRNSSQRFLLYDTAGPY
TDCDIKVNLTEGISSIRRDWIARRNDTYPIRKAKTNSDARGVKALSGDDR
VILKGIAGGAPVTQLFYAKKGIITPEMEYVAVRENALLEQAEAIPGLLLP
TKTRKITPEFVREEVACGRAVIPSNINHPESEPMIIGRNFLVKINANIGN
SAVLSNIEDEVKKMVLAVTYGADTVMDLSTGHDIHNIRELIVRNSPVPIG
TVPIYQALNKVNGIVGDLSFEVFKETIIEQAEQGVDYFTIHAGVLKSYIE
HTRSRTTGIVSRGGAIMAQWCLLHNKENFLYENFEEICEIMRSYDVTFSL
GDGLRPGSINDANDVAQFLELRTLGELVKIARAHDCQVIVEGPGHVPMHL
IEENVKKQLDFCDEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAM
LCYVTPKEHLGLPNAEDVKAGVISYKIAAHAADLAKGNPASFARDYALSQ
ARYDFRWEDQFNLSIDPATAKKLHDESLPGKGGKTAHFCSMCGPKFCSMK
LSKALND
>APH_0993 thiD, phosphomethylpyrimidine kinase
MYKGNVLSIAGSDSGGGAGIQADIKTITMLGCYAATCITAITAQNTQEVR
GVWELAPEVVKGQLEAVLDDLKVDAIKIGMLPVGLIGVVAESLPCEIPVI
LDPVMVSTSGFELTDPMGYTESIRPLAQNAALVTPNIKETEALSGMKNIR
TREEMVTAGNKIIQFLGIKAVLVKGCIWEEEEFVESVLIYDGKTVFFRNE
RAPGELHGTGCTLTSAIACFIARGLSLEESTRLAFDYVSCTIRNAPIVGQ
GLRPLFHNYFIVGDC
>APH_0960 thiE, thiamine-phosphate pyrophosphorylase
MDDIGFYLIVPDAHWFEFAASCGVRTIQLRAKDKPVSEVENMVKRCSEIA
VRYGVRFIVNDYWELALKYNAYGIHLGQEDIKTADLYRISSSGIRLGIST
HCYHEFARASFYKPSYIALGPIYDTTSKSMQFHAQGLELLKQWVKSSSCP
VVAIGGITLANIDDVVRCNAGGVAVISAVTEAADPKDAIRRFLDKCSVGV
>APH_1174 thiF, adenylyltransferase thiF
MKERYSQQVLVPEVGAQGQKRLLSSSVLVVGCGGLGSTTIPILAASGIGR
LVLCDDDTVKISNLNRQTIYREEDIGLSKVDVATRFVNKLNRDVEVIGLK
AAIGPRNFNTVLNDVDIVVDCVDRLAVKLFLNDACVAKNKVLIHSVAIGF
VGELMVINPGKSPCYRCFFEQQPVSTDLNCARAGVIGATVGVVGSMAAGE
VIKHVIGVSQPNTGKLHRIDLLNHNFTTYEFSKNPKCMCCGTDSTTDPYD
LESYEGKLRQHE
>APH_0735 thiL, thiamine-monophosphate kinase
MDEFQCIEKYIRPLLRSGFASENDDAAHVSSPTSSFIMTKDVLVENVHFL
NHSDPFLLAKKALRVNLSDIASMGATPHSYLLGLSLPKFIDEEWWKSFCA
GLQEDNSIFSIKLTGGDTTNNLADIIVISITALGIPSANILTRSNAKVGD
YLYVSGTIGDAALGLLAYNKKLIGEFSYLKQRYDLPQPRVMLGTSISNVA
SACIDVSDGLLQDIGLLCKLSGVGANLYAYEVPLSHEAAAAIMQNHDLLE
NVLAGGDDYELAFTVPPKYCPEVEQIATNIKIPVKRIGVITREQGIRVYD
RNNNLMKISKEGYSHTFS
>APH_0069 thiS, thiamine biosynthesis protein ThiS
MEDFIDVQINGKSETLNAGCTLSDAIAQCNVREPFAVAVNRVLVTKANYK
EHKLKKGDVIDIVYPMQGG
>APH_0310 ubiA, 4-hydroxybenzoate octaprenyltransferase
MFSRVKKVFGALVPYSQLIRLHSCEISLLATFPTCASIVLASNSLYSVLK
LFVLVAIGALVVRSAGCIINDIFDRNIDIHVHRTKSRPIACGRLKVREGL
CALAVLLCIAGVILLFTNKLSLYLSIICFCGVVLYPLMKRFFSYPQFVLG
IVWNFGILIGSAMAANEVKFGSILLYIGCIFWTTAFDTIYAHQDKVDDAR
LGLGSTALKFGDNTGLYVKRLYILTITMWVCAGVVSSLSWPYYVFILKSA
GVFYYQWRKTDFDNPARCMYMFKTNIYAGILLFLGVCLGRIV
>APH_1360 ubiD, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MSFRDLRGFLDFLEKKGELVRVGEEVSPVLEITEIHSRLIRSAGPAVVFE
NVVNEYGSSGIPVVANLFGTIERISYGLGIESCGLRDVGRLLAFLRMPTP
PESFRDLLGMFPILRNVVSARTTVVKKAKCQEVVLTGDDVDLRKFPIQTC
WPGDVAPLITWPIVVTHGPTNTREDNFNLGIYRLQVVSENTAIMRWLRHR
GGAQQYFRWKKEGKGDFPVAVVLGADPATTIAAVTPVPETLSEYQFAGIL
RKRPTELVNCITVPLRVPANAEIVLEGYVSASELLDEGPYGDHTGYYNSV
EKFPKFVIKAITMRNSPMYHSTFTGRPPDECSVLGEALNEIIIPMMISQY
PEIVDFWLPPEGCSYRVAIVSIKKAYPGHARRIVMGVLSFLRQFMYVKFV
IVVDDDICVRDWKDVIWAISTRMDPSRDMMYIEDAPIDYLDFASSETGLG
SKVGFDATNKIYPETKREWGVKIEMSKEIIDKVTSRWGQYGFEEKSQ
>APH_1075 ubiE, ubiquinone/menaquinone biosynthesis methlytransferase UbiE
MATQAEVNRVFSSVASRYDVMNDIMSFGLHRLWKRELCSRIVKHSGTLLD
VAGGTGDIALRALQQRGGLSITVCDINQEMLNVGRKKSIDCGQLSINWVC
ASGECLPFPDNAFDYYTIAFGIRNIPDRQAALKEAYRVLKPCGRFLCLEF
SPILEDSAFKTAYDLYSFFVIPKIGKIVAGDIDAYSYLVESIRAFPTQKQ
FSSEVADAGFFKITHKNVCGGIATLYSAWKV
>APH_0606 ubiG, 3-demethylubiquinone-9 3-methyltransferase
MSNVDESELVKFSNLASEWWDGESFSALHRINPLRVQYILENLQEATNSG
KRLLDIGCGGGLICEAMARLGFSVTGVDPCREGIEAARQHAAIEGLDIEY
HFTDIESFIHSSECSSYDIITLMEVVEHIPDLTEFLSSSCKLLKPGGMLF
ISTLNRTIKSMLLGKIAAEYILRMVPPGTHQWKKFVKPSEIHDALLKSRV
LVKDIKGITYKILHNDWVLNDRDISVNYILAAQKEQ
>APH_0749 ubiX, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MRIVVGISGASGAIYGVRLLQHLKNTDVEVHLVISNAAKLTLMHECADII
TLRELEEDLCYQCHNCENIGASIASGSFATAGMIVAPCSVRTMSEIASGA
ASNLLTRAADVTLKERRKLVLMLRETPFHFGHLRNMTALTEIGAIIAPPI
PSFYHHPKSITDIVDHSVSRVLNIFGFWDKAKEWQGLKK