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# Leptospira interrogans serovar Lai str. 56601, 56601

>LB361 hypothetical protein
MFMASKVKRSSFQKLLNAMKKMSLEVNDYEICRRLETIMMTSKEDLSQVV
VKSLLDNPLDFDPKTLPEPYGQYIRHFVYMVKRNKKQGIDTNFDSPINNL
KPPEKQTQTTEILKMPSKKEGSKKAPKR
>LB023 ferrochelatase
MLEDLGKKGVKRVAVYPISFVSDHLETLEEIGEQLKKVAYQNGILEYYRI
PAPGIYPKFIKAMAKIALESSQTSKKECLCKKLGGYNLNSVVCTRLIS
>LB024 ferrochelatase
MGFGGGSPLVSETNKQAAAITQILKKITGEIWESSVTMTCGYPNIRDIPA
EFLIPSNKNIIFPLYPHFSRSTVLSTAKLIEQIVGFCPVGAEGWVTPFHS
SQIYLESIRDLILDFFQGKLNRENFLHSDSFQEIPDWKTIDLVFSAHGIP
IRLIQKGDHYKEEIDSNITNLKKLLYKNGFSGECHTLFSE
>LB018 conserved hypothetical protein
MGRFVLKSSLEKLILVFGILFIFIFSISAETVLLQEGGSYRGKVITQNQK
TLTIQTKHGKHVISKKEILKVIYKDVSEEEEEKVRNAEIQRLEEEKLTKQ
RSLELKKQQEEEERLRREREAAEKNKPAPPPPPPPKKQPEVSRVGALARS
VVLPGWGQWASGRKFAAIIYPTLFLAAGYAVYENNRKYVVAKREYESYGN
PYSNSSLALAALGIPNPELPPVITDPVVLHFYNQELSPYQDKREAVDKAY
KNLQASIGVLAGIYVINLMDAFIFGGQISSTVGISNGATKGLIFDYNPMA
NSGTINGGFTNGPTFESKYTFGYRYQF
>LB106 S-adenosylhomocysteine hydrolase
MSVTTQEKDLSYKVKDLSQAEWGRQEIILAEKEMPGLMALRQEYKGKKPL
AGARIAGSLHMTIQTAVLIETLTELGAEVRWSSCNIFSTQDHAAAAIAKA
GIPVFAWKGETEEEYWWCIEQTIFFGDKGPNMILDDGGDLTAYIHEKYPK
LLSEIRGISEETTTGVKSLYKLLKKGELKVPAFNVNDSVTKSKFDNLYGC
RESLADGIKRATDVMLAGKVALVCGFGDVGKGSAASLRNFGARVIVTEID
PICALQASMEGYQVLRVEDIIEQVDIVVTATGNDDIITLEHMKAMKDGAI
LCNIGHFDTEIQMSRLNNEKGVTKKEIKPQVDKYTFPDGKSIIVLAEGRL
VNLGCATGHPSFVMSCSFTNQVLAQIELYNNKYELGVYTLPKHLDEKVAA
LHLEQLGVRLTKLNQKQADYLGVPINGPFKPDHYRY
>LB154 cbiA, cobyrinic acid-diamide synthase
MNIKIPRIVIGGTGSGVGKTTIALALTQILRKKGLKVATFKCGPDYLDPT
YHSRASQKICHNLDGWLMGKESVLNTFYQACHNVDIVIIEGMMGLFDGHS
PNSEIGSTAEIAKWLASPVLVVLDTRGMARTVSAILKGLKIFDPDLNLAG
AFANFTGSPSHIQLLKDASTEVPILGGLCKHSEQTFPERHLGLYSASEEN
VSEEKFNFWGEEGEKSLEVNSILEIANSAPEISIPVSNINTTLKRCKIGI
AMDSAFHFYYEENLMRLRQAGAELVFFSPLSDSKLTDVDGLYFGGGYPEV
FAPTLSKNKSLLNYIQDLSYKNIPIYAECGGLMYLSKGIKLVEGEFFPML
GLISATSIMEKKLKALGYVEVTTKKETIFGEVGLRFRGHQFRYSDLELDE
SNPIELVYNLRKRKSDQVSEEGYSKNSILASYIHAHWASNPNLAEGFVQS
CLRK
>LB150 cbiB, cobalamin biosynthesis protein B
MPWGIAISILVDLILGDPKDLPHPVRAIGKLARALEKFFRNNCSSEEIAG
ILTSCLVYLISFIIPFLSVQFANQLHWILGELLSIMIIYTTIAIRDMIDH
SKEVYDALVQTNLPLARKKVSKIVARDTENLSESEIIRACVESTAENLVD
GITTPLFYAVFGGPAWAMLYRSINTLDSLFGYKNKKYLRFGSFPARIDDL
ANYLPARITSYILVLSSLFLGYNFKNSLYILQRDGKKHPSPNSGLTEAAV
AGALEIQLGGVNLYSGVQNIKPKLGDPKKEFQIEQILQTNKLILLSSILT
FIFYILIYSGAAYFL
>LB161 cbiC, cobalamin biosynthesis precorrin isomerase
MNDMRQITNLGRNIENKSFSIIDEEAGPHSFAQEEWEVVRRIIHATADFD
YKNITKIHPQAIDSGIQALKKGCPIVCDVQMILSGLNPERLKVYGCKTYC
FISDEDVIENAKRKNSTRAIESIQKANSFNLLNESIIVIGNAPTALLEIE
KLIRQEGIKPALIVGVPVGFVSAKESKESILKLEYYNVTSIPYILTMGRK
GGSTIAVAILHALLLLSSKRGER
>LB162 cbiD, cobalamin biosynthetic protein
MTGKKLKEGFTTGACSAAAAKAATRLLLKGKPILEIETTLPNKRQVLFTV
KRCQLEGEIATCSVVKDAGDDPDCTHGAELTARVRLTKENEIKLKGGDGV
AVVTKAGLGLEIGQSAINPIPRKNIKEMILEELQGSSFNGAEVEISVPGG
QEMAKKTMNERLGLIGGISILGTTGIVKPYSTAAFKASVIQAIQMAKEYG
IDTIVLTTGGKSEKFAMDLLPNLNELSFIQVGDFIGTGIKTSVKESIRHT
IIVGMIGKLSKMADGVMMTHRGGSSVNTTMLSTIARSIGVPEEIAIEIQN
ANTARHVLEICKVSGYKIITTKICEIVAEKCSKHAGTNIMISCYMVDFDG
KLLGKCENFSPNVGLNL
>LB160 cbiE, precorrin-6Y methylase
MKAVTVVGMGDEGCPGLSSIAANAVAKAQILAGGKRHLDFFPQFSGEKIV
FKDDLTQTIKRIAELSLEHTICVLASGDPLFFGIGNLIRKKVGPEYVDFI
PAPSSVQHAFAKIGIPWDDAEVLSLHGRSSKGLITKLQFLNKVALFTDKI
NHPKEIASYLLSFNESEWTAFVCENLGGEKERIRKFDLKSLSEEEGIDPL
NVLVLIRNSVNWKPPTVVPNVSEENYSKRVPKKGLITKKEVRILSIAFLN
IREDSVIWDIGAGSGSIAIEAAQIAKNGKSYAIEIDPEGIEICKQNILLQ
KTDNVHVISGKAPEVLEKLPDPDCIFVGGSNGDIYEIIRISLNKLSPLGS
LVINAVTIDNVSQIYQSFKKLKLVPEVTLLNVSRGRVLKDYLRYEALNPI
HIFKIKKPEKM
>LB156 cbiF, precorrin-3 methylase
MKVYIIGAGPGDPELITIKGAKLIEACPIVLYTGSLVPKAVIERTKKDAI
VLDSSSMTLDEIISVILSAKENDQDVARVHTGDPSIFGSIAEQIRKLDSL
NIQYEIVPGVSSFTAAAAVLGKELTLPEVSQTIIITRISGRTPVPERERL
EILAQSGATLTLFLSVLHIRAIVERLTPYYGEKCPVAVIQKATWPEQKVV
VGTLDDIVSKVKREKISSTAIIFIGPILDCNDFADSRLYSANFSHGFRKA
KRNL
>LB158 cbiG, cobalamin biosynthesis protein
MKRNRKQYSVFVITKHGLEIAKKIQAIWQDIDLFVSAKFIQDAPSNSKLL
SFPMDKTLRETFREYDCHIFIISVGAVVRMIAPLLENKKVDPAVLCVDDK
AKFSICVLSGHVGRGNFFTEKLSEILNNIPVITTASDVSGTLTVDILGRE
FGWILENPDRNITKGCAAVVNETKVLFIQETGEPNWWPLDRPLPKGVEYS
ISLNNVQPEDYEILLIATDRSNVHKTHKEHYKNSVLYYTKTLILGLGCDR
NIPFEIVENGIYKILDENGFAIQSVRAIATIDLKKEESAFLKLSQKYGWE
LIFFSPEELDRVSQVRSPSEIVKGFTGTKSVSEAASLLASGADSLLLTKQ
KYKEEPNGKNLTIAVSRIPHPKRPNLHRSVLKADK
>LB157 cbiH, precorrin methylase
MKKGRLNIVGIGPGNDEHITPAAFHAIQEADLVIGYVTYINLVKHQLVGK
QVTQTGMTEEIDRAQEAVNTAKEGKIVTLVSSGDAGVYGMAGLVFEVLRK
MGWKKEESPEIKIIPGITADSSCASLIGAPIIHDTARISLSDLLTPWSVI
ENRLKCAAQGDFVITLYNPASGRRQRQIVKASKIIKRHRSGDTPVALIKS
AYRKQQNVFLSDLDNFLNYEIGMNTTVIVGSSNTFVYEGFMITPRGYTNK
YSLEDASLKEGQKKGFSLRTIEDLKSNTNLEDTSLNLNVTKIRGAFIKKS
TSIVSDQELSKSPASITNTDSSKIQSQDSSAIKAIKTLDLLSKIQKESSK
KSHKQLEPGKKTLAYIGRLGGAILFKTLEKFYIIGKLKNSICFEEYGFQN
PGENYNKYLELKIVDMEKVLNFPFEFSMFLPNQILPEEIYEKLVIHRNSS
ISERLLNYAYEKSERVFLNGQEYRDISWLGIIPLEVWNLVRGILLKC
>LB151 cbiP, cobyric acid synthase
MFQGTASNVGKSILTAALCRILSQDGIKVAPFKSQNMALNSFVTLNGEEI
GRAQALQAQAAKILPDIRMNPILLKPSNEKDSQVIINGKPLNSMNFKDYD
QYKPIAFEEVKKSYDSLASEYNVIIIEGAGSASEVNLKKNDIVNMKMAEY
AKADVLLVGNIDHGGLFGSLLGTMETLTEWERKLVFGFIINRFRGAKELL
KTGINYIEEYTNKPILGIVPYIKNLKLPEEDSLEFKSGALDDTSKLEERL
DVVLIDIPRISNHTDIDALRAEPDVRVRIVRTVEDLGEPDVLILPGSKNV
ISDLNHLYDVGLVNKIFALSRNQKTDIVGICGGYQMLGKNIFDPYRIESD
QGSIQGISLLQIETILEKNKSLKRVFATHIPTKTEVEGYEIHHGKTKSIG
NTRVILLNEKAEELGHSDPTGRIWGTYIHGIFDKDEFRRKYLDQIRIRKG
KSPLVKVQVSYNLEKSLDRLARYVRQSLNINLIYRKLGLG
>LB155 cobA, cob(I)alamin adenosyltransferase
MNSDEKNSKGLVIVYTGNGKGKTTAALGIVFRALGRGLKCGVVQFLKGKW
ETGEKMFSKKIPELDFHVMGLGFTWNSENLDKDKTAARMAWTFSSKMILE
ENYNIIILDEITYTFHYGWLNVEEVINILKKRRKDLHVVITGRNCPKVLM
DYADLVSVIEAQKHPYQNGIPAQKGIDF
>LB159 cobI, precorrin-2 methyltransferase
MNLSRYGKLYGVGVGPGATDLITLRAVQILNSVNVLAIPKTSEHLKPFAW
RVCSPIIQENPSQEKLFLHFPMTKDPDILVPAWDKAFTEIGKRLEKKLNV
AFITQGDPSVYSSWSYLLEEANDRWPGIEIEIIPAVSSITAIPAVLQTPL
ADGRERFCVIPGTYGIEELPKLVQHFDTIVLTKVGQIIPKLVQILKKLNI
LKNASYVSYATTDRQKIVTNLETIQNESCDYFSTVILSIRKRKGILRGQN
CETE
>LB152 cobP, cobinamide kinase
MEKKQIQSKNKKMQIPTITLITGGCRSGKSRFALELANDIKGKKYFIATC
PTFDEEMNQRILKHKKERNHFIWETIEEEFNFLNLFKSEYFLEKSIIVVD
CLSLWINNLLYKSKIEKRKIEEVTIKKSCTKLLQHIRNTKVKHVIFVSSE
VGLGLVPESKAGRIYRDLLGICNQTIAHNADYVYFMSSGIPIKIKGQIKQ
NQKVKI
>LB010 hemA, glutamyl-tRNA reductase
MWSTLRVYHSIQKDRENLKIPGSYFWSTCMRTIWITDSRIHREPSNLPVT
LEKYSGYQGYRFVLEVISGLHSKLLGETEVLAQFRNKFKVLPSSAFGEYL
ARLRDSLIQDSRSIRSRYLQNIGEQSYGGLANKYLKDHDFVSVLGTGQLA
EKVLPWLKHRNILLVGRNQKRLLELSKQFNVTIKLLNDWNPTKGAIVIAA
PIDLSGYINSITSGTVVVDFREVPLEKNWSNTISYISFAEMLDSIRETEE
RTWQIRKMLQPFLDELVKERELEAQQFIFGWEELTCPAF
>LB012 hemB, porphobilinogen synthase
METKQRRIRLNAGLRNLASSESLNSKKLIQPIFIVEGLKEKEKMDSLPGV
FRDTESSVFKQVESDLKAGVTHFILFFIPELKSNSEIPKSFYERSISSLK
KKFPESFLWIDTCMCSLTTHGHCGLLHPDGSIDNHTSVKHLSDIALVYAQ
SGADGIAPSDMMDGRIKSHRSILDVNGFSNIPILSYSTKFKSNFYGPFRA
AADSAPAQGDRSSYQIDVRNREDAVLSSIRDKEEGADFLMVKPGMTSIDL
IGPIREKTGLPTGVYQVSGEYASIHYLSQNGFCDFDSALSETWQIFSRAG
ASYLITYAARRGKEILS
>LB011 hemC, porphobilinogen deaminase
MGRTDLSRILKIGSRKSALAKLQTYLVLGALKKKFPEIQVELFFREASGD
QDLQTPLWKMGTKGVFTQDLTADLVEKKVDIVIHSWKDLDLEGHPDTTII
GVLDRADQRDVLLWKKSSLSKYSPSVLKIHTSSPRREYNLRKFLSFSLPS
RYTNSSLVFLPIRGNIQTRIRKWKESDSDGLVLAKAALDRLLSEDFFNSD
ELEYQEIRKFLKDSMDESVYQIFPLSLNPTAPGQGAIAAEVRTEDNWVLD
RIRTLSKSEVVLAVEEERKILKRFGGGCHQKIGVSILQKAYGKILYQRGL
SDSGEVLEVEEQFSEIFAPPADSVSKVYPVPGEAVKQKRTPLDSSNGLIF
SEDGQNNKTIFPTELILKDWLVTRGNAFPNLSPALEHTGLIWTSGLKTWF
QLAQRDIWVHGSLDALGEDELPKHSIFGKPLDFIKCTHLGSTEIASGLGR
VLTYQTQAMEDHPDLSEKTHFFWMSASQFDKALSIFPQICNGFHACGPGI
TYSHIRKVLGESANLSIFIRYESWLASLGLEEFKGKKIGNQTEKNSP
>LB016 hemE, uroporphyrinogen decarboxylase
MVINGPEKSKMPNERYTNVLNGIAQKIPPVWMMRQAGRYHKHYQTLRTKY
SFEELCKNPDLAAEVAYGPVDEFDFDVAILFSDILFPLEALGMGLRYTDS
GPVLDLEIRSKEDLNKLKSVEDSISFMQFQKKAIQRTLEKLPKEKSLIGF
VGGPWTLFTYAVCGKHEGNLFLPKTLTEVRKEFLEKIIQFLKENISIQLE
GGAELILIFDTAGGDLSPELFREIVIPGIKTLSDFYPGKVGYYGRGTSSI
HFEMIREITTLAGFGFDHRWNLREIFKTESRMIQGNFDQSLLFLGKEEFK
KILMNYLKPFRELPPAERIGWVCGLGHGVMPKTPEYNVKTFVEIVRDTFR
>LB017 hemF, oxygen-independent coproporphyrinogen III oxidase
MGLWSGARCDAKNARIQRENIRRNCERYVSMTTVKDLIAKYDIPAPRYTS
YPTVPYWSENPTTEEWLEKVRNRLRFENTSLSLYLHIPFCETLCSFCGCN
TSITKNHSVEDPYIESILLEFSNYLKEVPEIAKRELKELHLGGGTPTYLS
EKNLEILLDSILKKMNLSSKYEFSLEVDPRRTRDTQLKILRDFGFKRISL
GVQDFDPEVQRLVNRTQPFEMTERITELSRKLGYTSVNFDLIYGLPKQNL
QNMKRTIKKTLELRPDRIAFYSYAHVPWLKASQRLFTEVDLPSGSAKREL
YEVSREMFLKAGYIEIGMDHFALESDSLFQAVKNGNLHRNFMGYTAKTTD
MLLGLGVSAISDSWDCFHQNEKIVKKYQKRIYSEGFATLRGHKLNEEDLI
QRSLILQLSTSGKVIVPEEILREVRLYLASMEDDTLVRWEGNLLSLTEKG
RPFLRNVCTSLDLRLRRKSPELRVFSSSI
>LB020 hemG, protoporphyrinogen oxidase
MRTQSPDYIVIGAGFTGLLYSTLAVLEGRSVFLYEKQNRSGGLVGSIQTP
FGLVETAANGILNSYQLEELASALGLNILTTEKKSKKRFIWKNGSPRRFP
LSFLDTLRVLYGILGISAEIRAGESVYQWGVRVLGKGAVKNVLEPGLGGI
YAGNLKDMSAELALGSWISSKGSLLKNIREIKKIKTKNPKQKKGTVSFRG
GLGELLNAMEAKIKSSPNSKIYYSQESPTLSSIRKKYPNSKIILSCGLES
SLKLLSSGFPVFKKYEKLCKTLGVVTVTRFGNQPLLGKKSGFGILFPSDS
GFRALGVLLNSSIFSGRVSKGHYSETFIFGGALDQEIVKFKEKEIINVLE
EDRKKITVQNDEPLNHYVTIWKSALPIYDLALLEFNKELDRSLPEGIFVE
GNFRYGIGLSSILERAWNVMRNQKGRT
>LB013 hemL, glutamate-1-semialdehyde aminotransferase
MNQNKPTSKLISDFWKGKTSEELFERAKKVSPGGVHSPVRSFRSVGGTPV
FFASAKGATLTDISGKEYIDYCLSFGPLILGHRDPEVEEVVRETTEIAWS
FGAAEPYSLELAELISSRVPWAEKVRFVNSGTEAVMSALRVARAATGREK
ILKFDGCYHGHLDSLLVKAGSGLAGESSSDSAGISATSIANTLVLPLDDE
ASVERVFETEGKNIAALIIEPLPANYGLLIQRKEFLLKIVETARKYGTLV
VFDEVISGFRVGFQGMSGLLGIWPDLVTYGKIIGGGFPVGCYAGKKDLLD
LVAPSGPVYQAGTLSANPFGMRAGLATLKKVQRDSIYSVLDDRTKIFTDT
MTKLLNKKSNQEWEAVIHSSLFWFRKKTQQPIRRIDLIPEGHKESFAKVF
HTFLKNGIYLAPSGYEVGFLSWAHDDEIIAKTLEIADKALKTF
>LB335 phhB, pterin-4-alpha-carbinolamine dehydratase
MPILRRLIPLLLNYDPSRILFIDCILVENKTTTLCGRSFMSDLNNADLEL
FKQKGWEIKFRTEIPLLSKTFLFPTYLSGLEFVNSLAHIAERLDHHPDLF
LSYRKVTVEIFTHSKNTITDLDLRFAEETETIIRQG
>LB215 ubiE, ubiquinone/menaquinone biosynthesis methlytransferase
MSGFQMPQANFKAGFVRENFNKIAKKYDRFNDWNSFLLHRVWKNHLVREI
ENNFSGHLHVLDLCCGTGDISLRLENSSFVDHVTCVDFSENMLEIAKTRL
KKQAQKGRVHFELGDATKLIQFQNSQFDVVSIGFGLRNVDNLSKAIGEIF
RVLKPGGMFLNLDVGKVKNPWIRWIADFYFFKIVPILGYILWGGKNEMFD
YLPVSSLSYPDQETLQLILEKEGFQRVQYKNFVFGNVVLHVAKKPSEKT