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# Tropheryma whipplei TW08/27, TW08/27

>TW063 putative ubiquinone/menaquinone methyltransferase
MGTNIHIDMVIHGKHTAEIRKMFNRVAQAYDRTNLVLSFLQDAHWRRAAC
KMLGVTAGEEVLDVGAGTGASTRTVARTGAAVTGIDISPRMLQIARNRCK
RFQNITWRLTNGDLPFPDKSFDAILMVFCLRNVSNIQGFLCDAARVLKPG
GRLVVCEFSHPRRFVAPFYRLYLRYVLPRLAKLISSDPAAYEYLTESIED
WYEVDELAFMLEQCGFQNTSWKRLSFGAVALHRALRGPE
>TW505 conserved hypothetical protein
MTVGVLSLQGSFYEHLSILSRLNTDHIQVKTSEDLSRVTRLIIPGGESTA
MLALTQKSGLFDLVRDRIMSGMPVYGTCAGMIMLSTFVEDFPNQKTLSCL
DIAVRRNAFGRQINSFESEVSFLNSKITVPFIRAPKITQIGEGVDVLSRL
ESGDIVAVRQGNVMATAFHPELTGGAAVHEYFLHLGLE
>TW011 putative glutamine amidotransferase
MFKVLVIDNHDSFIYTLVNYLQQLGVTTSVVRSDNNCHSVESMLGVHDAA
LISPGPGTPEESGITLSVIRAAYSTSTPLLGVCLGHQALAVAFGGDIGPS
GRIMHGKLVTVRPRPSAIFKDLPTAFTATRYNSLTVTKVPQALRVIARAD
CGEVMALEHRTAPMYGVQFHPESAVSEWGFRILGNWLYISGFNKALGISR
DLPIVVYNTRVR
>TW506 conserved hypothetical protein
MGLDNLKVGLAQMLKGGVIMDVVTPDQAKIAEDAGAVAVMALEKIPSDIR
ASGGVSRMSDPGLIERVMDSVSIPVMAKVRIGHFAEAQILQSLKVDYIDE
SEVLSVADSSYHIDKRKFTVPFVCGATNLGEALRRISEGASMIRSKGEAG
TGDIAQATKHIRAILSEISALTQAREDELPARARELGAPIDLVRETARLG
RLPVVLFTAGGIATPADSSLVMQLGSDGVFVGSGIFKSEDPKAYAAAIVQ
ATAQYDDADLLARVSRNLGQAMPGVSNLDVRFSSRGV
>TW641 conserved hypothetical protein
MGGAGLLTDQYELSMVNAARISGIAAKECVFEVYSRALPPGRPFGVFAGL
ERLLEKIENFSFADDEITWLREKNIVDNETLDWLRGYSFSGSISGHKEGE
IFFPNTPVLTVRAPFAEAVVLETLILSCINFDSAIASTAAQLVYRAKNKP
VYEMGSRRTNEQAAVAAARAAYIAGFAATSNLAAGKIWDIPTVGTMGHAF
ILAHKTESEAFYAQVKQGGGNNITLLIDTYDIQEAIDSAVTVAGKNLAAV
RIDSGNLPEVVHDVRRKLDLAGATETKIILTGDLDEASIRLVSTAPVDAL
GVGTSLVTAGGFPSAGFVYKPVACREKNRWRMLSKKSKNKVSTGGQKNVQ
RVLDKNKKIIKEQVLVFDPDNPPVTTYDTNVLQITSEHIRYGKRVAINST
NEIRAYHKSVINQIPEEVFNLEGKINTERISWHSVQGHRLEA
>TW176 putative integral membrane protein
MNKTAALVAALIVFSAVIAALASQVLSELGYSVFVPSYTFVFACLALALI
QIILAIRIKLVLVKGKRAINPAFAYRILALARSYILAGSLFFGFFSGTAL
YFVRGGFIPEKFYLLIPPAIASLIVIIAGVISKFLLRIPKNHGAAANLE
>TW554 putative polyprenyl diphosphate synthase
MTLLEMVNTKISRFILNNKTSKHTESMYDYLQDFTFGGKRLRAKLCFTGA
ECIGPIPENLFELISDIAVAIELFHAAALVHDDLIDKSDSRRGLPAVHKR
FAKFHEENSFVKCKENFGTASAILAGDMLLVWSSRFFYSALNNLLNTTAK
QASDFHLDTMNILWHEMQNEVVIGQYMDVLHEHRWRQLSVQEALDISKEI
MIKKSGKYSVQVPLCLGANTNGATIEHLEVLKRFSLPIGLAFQMRNDIDG
AFANDKITGKPSSDLSSAKHTMLIGLARIHSTKHGRIRLEEILGQADNEE
EIRAIVTESGALREAENLIKKWTDQAMEIIKEARLHSMGKEKLIKIASWL
SQAT
>TW745 porphyrin biosynthesis protein
MRHSCHHVWITRGGQWAREIAGMLKVRGVTSVVHPVIDCVPVMGYENELQ
KIPFFDWLIVTSSTTAGLLNTPIPQSVKVAAVGRETAESLIRAGHRVSLC
PENDFSSDGLASAIQAHLNFPRRTCDSVISQRILILTSDLSEGFLKSALE
RMGHKVTVLVIYKTVILDIPPMPQLDNITAAFVTSGSIAQGIAKTGLFFD
LPLVCIGHKTAEICQRSGLRVASIARTKNKEGLVQALFELS
>TW690 conserved hypothetical protein
MFTKHAIRQLIRARRISRVNLQNSYICNKEHLGRSLTLARNLQIVTEKAK
CITCYLPIKGEPDTRYFMTSNKHLKVLLPVIIDRQLYWRIWRNAKEHQGP
FGTFHPAGKNLSKHFLDKTDVMLIPAAAVDKRGYRLGWGKGYYDRYLARV
KRSIPVFAVVFDNEIFDEIPINDWDKKLTGVVTEKRILYFSRTHKPQVRT
RSK
>TW378 conserved hypothetical protein
MSKAIQDFISEKYKFPKDDWICANYIQSFSGNLNSDNCTSDTLSNPRDRM
ILHTIREANDAVFVGARTARVENISVKNKPLIVLTNSGNLGGISANRNTI
VIAPKTTETQIRHTIGASVNVIWLDNFGDITRYSQTMGVLIAKAVKSLGF
KRIVCEGGLTLIRMLLSAGAIDELCISIVDKNSTGPRIDTDTLCTPKLTQ
VLVDQEFYKKQRIKSVYTRWVLQNRRGRDEE
>TW408 putative flavoprotein
MMQNAIGRIFLGVCGSISAYKSVYLARLFVKEGYDVRVGFTNGASQFVTG
EPFRVFTGHHVLNFPCDDQSHIDISRWADAIVVAPATANILAAARAGLAS
DIVTQTILSSRSPVLFVPSMHTAMWENPATRDNVNCLLERGYHVLGPVTG
DLSSGDWGIGRMVDPCEIVQYVSRSLLNHQTGKLSGKKFLITAGGTRQPI
DPVRYIGNRSSGKQAIAIAKEAQKRSAEVILIAANVEAVTLPTGMRVITV
ATAEEMRKALSDNIDTSDVVIMAAAVSDFQPREVASQKIKSNDGWTLQLI
STDDLLRELASNKSRPRVLVGFSAETEESANCRIDIARQKLLSKGCDYMV
VNQVGFDVGFDVSDTEVSLIDDKQVFFTARGSKDYIAKRILDFLSERVIV
TYIDPLDRSL
>TW064 putative polyprenyl diphosphate synthase
MLVSGIFLSDILDPSGSLSDDISPALDRVEDLLLETVGDCHEIVSHLLVS
GGKRARPLLVLLTSCMGSGINDAVIRAAAGIELIHLGSLYHDDVMDNAYI
RHGSITAHRLWGKSAAILAGDFLFAKAGVLGLNLDKRAIAVQTEAFQRMI
SGQLSETLGISDSLDPLEAYIEVSRGKTGSLIAASAQVGAILGDASLSTL
EPLRDFGESIGVAFQLVDDVIDLSGKSGKTPGSDIRAGVMSLPILLLSNA
AKDDRDSAVLLEEIERVRRHSGACGSDDYSSEMNAVLAHLRKHDVTARTL
EIARTWGDKAKHALKKLPECAPRDALLAFVETVVSREF
>TW227 putative aminotransferase
MNTEYLHVLWFNPDTDCEPRFYDVHHPLIPATSDAINRGVGVFETIGILS
GRILNLDEHLERMCTSANRLGLRSIEPDRWRSLILQSAKKIADQERAGLR
VVYARNSNRSYLAWIAAFAVRDPDALSKGIKVITLQRGVRSDAGRLYPWL
LFGAKTVSYAVNMHALEVAQARGADDAIFLSEDGLVLEGTTSNLIAYNKG
AFITPCPRTMSILPGTTQKRLFMLLEAEGKKTLETSVATEALYNSEGVWL
TSSVRMITPVVSVDGNRVRFDPGLTDWLNELLARSAV
>TW068 putative iron-siderophore uptake system ATP-binding component
MITVDKLSFSYGKNKVLHDISIEIKRGSFIAIIGANGCGKSTFLRSIAGL
NRFEGDILLDKQHIRRLKPKNLAKHIAFLPQQVNLPEGLTIADLVSRGRY
PHQSILHRWTKTDEEVVKESLQAVQASHISQRAIEAVSGGQRQRALIAMV
LAQQTRILLLDEPTTFLDIAYQYEILELLASLNRESKTIICSLHDLNQAA
RYASHLFVMGEGRIIASGEPKKVITENLIENAFGLKSRIIDDPESNTPMI
IPRKSENLKRL
>TW062 putative chorismate binding enzyme
MLPIEVEITRIGNMDRSDFKRQYIRKVLSWDFVYCTHSTMMRTQGRVLKI
NLDSYSAEARFEAAESLINEIHTKIQYTSENLNPIGLIVLFGFTFSPYSA
RPSFLAIPEQMFFWSDGVAWKIDATICHNLSEPSRIFKWPKSISFKMGDF
RQEDYKHAITNVVNKLLNADISKVVLARDIIAEIHDDFDPEAHAIDLDEA
IQRLMNTANGTVFVFDGLFGASPEVLLRTDGNSGFEVSILAGSMSANHPK
HVIHNCAASPPYKALDETYLDEKLRLEHSFALNPTLERLSTLMNTAPTVN
SYKIRRFTHITHVASFISGTFKPNISPLRALSHIHPTGAIAGEPRERALE
IIKEIEPFDRELYGGAIGWIGQDSSCEFTLPIRCAQLNRGHIKAFAGCGI
VKSSIPQKELEESTLKFKTIIDAIS
>TW026 putative protein ligase
MFPCVFLDTVGSTNLYLLELLKAKDLDDFFAVFTTNQTAGRGRMARSWEC
KKGIALSVFLKHNLPGAYINWLPLVIGLAVVKAVNKMLEDATLPHRADIK
WPNDVLINGKKLSGILIETPSDGNGLIVGIGLNVAVAPIATSICLRQVGL
QASPKEVVSALLAEMHTIYQQLIALAAKDISFKDSECFGEIMRLCSTINK
TVRVTGTKTFVGVAQGLDSLGRLVIRHSGDTSIVSAGDIEHLRAIDSL
>TW008 conserved hypothetical protein
MLGMGVCYIYGAGEHFTPPEEVGMHDLVIAADGGLMQLKKHGARIDLYVG
DLDSIESIPINIDRVILPREKDKTDMMQAALIGAERGFRTFCIFGGTGGR
LDHTIGNIQLLAELTNMGYSVFIVGKYDVVTAIRNNEIYFPSHFTGNISI
FPHSGDASGVYEEGLKYALNNAHIPGTFNGVSNEFIGVKSRVAVESGMLL
VVYERQGGRMHLNISTCAMTAGNQIQKPSG
>TW280 Dxs, 1-deoxy-D-xylulose 5-phosphate synthase
MCTKRQYGLLESIRSPRDLDSFTPHQLDELECQVRDFLIQSVAKTGGHLG
SNLGVVELSIALHRSFRSPEDCIIFDVGHQCYVHKLITGRHDFKALRCKN
GLSGYPSRHESNHDIVENSHASAALSWADGVSRARTLLGNDNYVIAVVGD
GSLTGGMCWEALNNISDDNNRRLVIVVNDNGRSYARTIGGIARFLNAVRA
SKSYLWLRESSEAVFSHMGSPGRRLYQGIRGAIHGFLSRFSSSNKLFSNL
DIRYLGPINGHNRKALEKAFKQAKQYARPIIVHVITEKGHGYPPALEDAL
DCLHTVGVIDPSTGKSASVQGQVRQDTWTGVFGEELLRLAESNTNIVAVT
AAMLHPTGLSMFAEKFPHRVFDVGIAEQHAVASAAGLAYEGLHPVVAIYS
TFMNRAFDQVMMDVALHGAPVTFVLDRAGITGPDGASHHGIWDLSLLRIV
PGIKLYAPRDASTLRNTLALVCSEDCPTAIRFPRGSVCDDLPALRSLDDG
IDVLYGSCDREDIVIVAIGVMAHACVRAAQLLAESGIESTVINPVCFWPL
HRQVLARVSKAKLVVLAEEGAKSPGLGDYIAGRRLLEFVIPGDFQPQGSR
DELLDAIGLNGEHIARKIKARFNQIINCV
>TW156 coaA, pantothenate kinase
MGIEVFKKDITKTYTEMLKDIRKRVRERGKVGKSFIIGITGSVAAGKSTL
ASDLAKMLDGISVEVISTDGYLYPNKILEQKGLMLKKGFPESYDTAHLAS
LVKNIKAGAKTIGIRQYAHPIHDVTGVIKTVNKPEILIIEGLNVMRHPVK
TVVDLGIYIEAPKRSVFKWYVKRFFELRAQHEKNTYFRKYANLPRRQCIK
MLKQVWRDVNRKNFTENILPVKHTADFIVYKNPRHKMTLYRNEASSSGFP
V
>TW196 coaD, phosphopantetheine adenylyltransferase
MSNRIAVVPGTFDPVTRGHMDILTRTSRIFNTLYVLVANNPDKTPLLPMH
DRVDLVGQALEEYGFPRSEPKCDSESDRNGPIVKIHRFEKGLLVDCCKQL
GATVIVRGLISADAHREASMAYANRNMSGIETVFILPDPPLSVVSSSMVR
QLIALGGDISPYVPACVTRFFGTHSG
>TW478 coaE, dephospho-CoA kinase
MVMQLFALTGGIAAGKSCVAGLLSEFGLRVVSADSLVEVLYRTDVRLIEE
IKGRFLCNDEKSLSELVFSDSRARRVLNQLTHQRVNRLALDYFWQLRNEP
VVIYEIPILESTSPFVGFAPGECGVFASGKIQHSGVLFVHSDCESRIDRL
MKRNNLNRIQALQRIHSQTPYMPQYSLRAGDLLRTGDLSHDFREERAPHK
GVKVYSVHTSGVSKTLCMIQNTSDFSHLRQCVASVFQIMKTIDRSV
>TW288 fgs, folylpolyglutamate synthase
MSRAGEALPQPRLDGTKLALSYLSNPQECAPVIHITGTNGKTTVSRMIAC
ILTSLGLRVGLFTSPHITALEERIQIDMNPVQGHILEKHWFDIQFQLRLA
DAHLEKKNCPPLTFFECMTVLAFSCFADTPVDVMVLEVGMGGAWDATNVV
DARVCVFTPIDFDHTGRLGSRLEEIAHTKAGIIKPGSFVVAAEQHQVVQE
CLEDYFASINIGCQSYDTELPDKIRFFGQDFDCDYKPVAGGQILDLRGLY
GECNEVFLPLFGGYQAKNAALSLAAVESFFGRVEHDIVLEAFSNITSPGR
LQIISKNPVVLLDAAHNPHAAKHLAIALDEFFSFGKIVFILAFLSDKDIE
GIIRNLMSFLHGSLRVTSDSVGYSESESTRFSNPRVTFVITQSTHPRAVA
ADVAFSIAKRVVANEGLIVCESANDAFQYSTRLNPDAIVVSGSISILSSF
IPR
>TW653 folD, FolD bifunctional protein [includes: methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
MLDGLAVSAGIFERLHRACCELENNGVCPKLATVLVGNNPASRSYVLSKH
RDCNNIGIQSTLIELPANTSEKELISKVEILNASSDVSGIIVQLPLPESI
DQNKVIEAINPDKDADGLHPLNLGYLVTGKQGIVPCTPAGIVKLLEAHRI
TLEGKTIAVIGRGTTVGRPLGILLSGKGVNATVINIHSRSRNISGLSRIA
DVVVACAGVKHIVEPSWIKPGAVVVDVGINQSGVSSSGKMILTGDVHPLT
KNIASYISPVVGGVGPMTRAMLMSNVINLSERDFRKRLYAS
>TW174 folE, GTP cyclohydrolase I
MTKLCRFESGSAQSAVANLLSALGQDVGRLKETPSIASSGLESLISGSET
NPADCLVDLIPNTQKGIVILRDIPFRSICEHHLLPFVGTANLLYEPGKFL
AGLGNLTSLVRCAARRLSIQERVTDQIADAIYTGLCARRVLVSLAARHTC
ILDEAGNTEVTTFAHRGIGDADIISFMTIIR
>TW175 folP, dihydropteroate synthase
MMNMSYTPDPFPPPNVMGILNITDDSFSDGGLFLDPSAAITQGRKLFAEG
ASIIDVGGESTRPGAERISVEEEKKRVLPVVRELLSEGIHVSLDTMNADT
AKEGLSMGVAIINDVSAGKADPDMLRVIADAGCKYIAMHWRGHSMFMDSL
AHYDDVVSDVLRELKFDIERITAAGVKSDQIILDPGFGFSKTSDHNWQLF
RNLDCFVKLGFPVLIGLSRKRFLSRVFKGHDFSPKDSKNVGGLDNREILA
RDLPSGILSAIAITRGAWGVRVHDVASAHTALRTLQLAQYGSVYQAHKRA
ANTGIDTAIPGQGNTDDTTASSNHTNNSETGASLKSGVSQVRNMIAPPVI
KIRSLRVYAYHGVYRSERDYGQQFIIDADIQLKHFPEDKIDSTLDYDSLT
GKFVQYATASSVNLIETLADHLAKIAVLDPMVEWVSLSITKPNPPLAYMK
QSNTAACHAMHKPDTRGDYAKEHTNLTGLQLSCTVRKVRSESVTRVYIGI
GANVGNCLDNVQRAIKDIADHPMIELVSLGRLFRTTAVVGESLDESLPVF
LNTAIAIDTALSMQDLLALMLCIEKKLGRTRHSRTRHSLSSAQDAHQADS
TSDNPNQLHYPCAGRQGIQQPLHSSTLAHTQDGFVNRHIDLDILLAEGVQ
ITEHGLCIPHPRLSKRAFALLPLESIDPDLHIPGHGPITDLIHGLPEDQI
SSVATLRDSGYELFRHSITRLNNCSAHNKAYVTPSAGQNYDSEQDFDAGL
SHTESRGKTEPHGKI
>TW750 hemA, glutamyl-tRNA reductase
MLLCVSANHKKTSFTVLEQLARVSPDFASELVEAEDIDGAAILSTCNRFE
VYIDAIQKGDQDDVCKTGLLVQNRIGELCNISPSTIIEQTSFLAGCEVSR
HLFSVATGLESMIIGETEIAGQVKRALTYAQKCRTTSPELERLFQRASAV
NRHIRQSTKINEVGQSLVSLSLDLASSRIGDWSGVRAIIVGTGKYASKAL
ALLKERGVVDISVYSPSGHVNNICNTEGVRNIFNLQTALSGCDLVVGCSS
VDKPVITKQDIETAQASGSRTSRVRPVGRPSTDLTAIEASNRSRHVLIDL
GLPRNFDPAISDLPTADLIDLDMLRVHAPFDNLAAEKMAHELAIESSSQF
VNDCKQHEATPVIVSFRNYLESLTQTSLRRTDNCKHAQHALKHFVNSLIH
IPLTRCKQLAANGESHKFAESMEILFDVKTDCTEGTQYQSSCGKSFD
>TW744 hemB, delta-aminolevulinic acid dehydratase
MFQKIRTRRLRLSEAMRRLASEHVLVPHKLVLPIFVGEGLQPRPIPSMPG
VVQHSIDSFKRELQKAACAKLGGVMLFGIPDSRSEGAEDAFRPDGILNKA
CSIAVREVGDSLLIQTDLCLDEFTQHGHCGVVSKDGSIDNDATLEMYAEM
ALAQAAAGSQMLGLSGCMDGQTGFVREVLDSNGNHDVSLVAYSAKYASAL
YGPFRHATNSPFSGSRKTYQLNPANLREAIRKIEVDISEGADALIVKPAG
YYLDVLRCASEISRIPVMAYQVSGEYAMIKSAAAWTDTKQLVIESLLSIH
RAGADAILTYWALDAASWLSETF
>TW746 hemC, porphobilinogen deaminase
MYPLRIGTRSSLLATAQTAQVQKTMRDVFLLDTQQVLIQTGSVRRRDGSF
VAALRTALLEGECDLAVHSLKDIPIAPHEGTLITAVLPREDPCDVLCARK
DLTLTTLPSGAKVGTASARRRAQILNFRPDLDVVSLRGNIDKRLIHLDTL
DAIVLSAAGLKRIDREDAITESFDIHDWPTAAGQGSLAIEVCRAQLDDPQ
NRVAVTYRLDNPMARVTTTAERGVLSLLQADCFSPIAVHAVYTANDKSLR
LHAKVFSRDGKIFCESIRFARLVKQLTDTNQNHTKNSGSDDIGNALEVAM
TLAKTVVDELLSKNAREILKQ
>TW749 hemE, uroporphyrinogen decarboxylase
MTGASGVEGTRIPLHSLSCRPSAGRSAGSFVNTGIMEAFRGTRPGCLPVW
FMRQAGRSLPEYRAVRGTNTLLEACLNPDLACEITLQPVRRYSVDAAILF
SDIVVPLKLAGVGVDILPGTGPVLNNPIDTPDRVNTLLAKTADSIDFGII
AEITRHTVSVLNGIPLIGFAGAPYTLACYMVEGGPSKTHMKARAMMHGDK
KTWQKVMMLAARLSGQFLAAQITSGAQAVQIFDSWAGSLSRKDYVDNVAP
FSKMTIDLACGIDGNSDLSKTGKSLWPRVPVLHFAANAGHLLTAIRDIGV
SVMSVDYTKPLDEASELLDDSMPLQGNIDPAMLFAPWEVLKRHVLDIVQR
ASRAPSHVLNLGHGVPPDASCDQLARIVDLAHSMV
>TW747 hemH, ferrochelatase
MIRRSAVSRVVAEGSAIASDSGFALGASQYDAVVLLSFGGPEGPEDVVPF
LKKVTSGRGVPDERLYEVAEHYNHFSGISPINDCNRRLRGALEKELFSRG
IRIPVLWANRNWQPQLEEVLREAYDRGFRAFLTLFTSAYSCYSSCRQYRE
DIAHAVERAGLSGRIIVDKLRQFFDHPGFVLPFIEGIQDCLEQVKERGFK
VSRTAILFSTHSIPELDAAFSGPEDAHFGKYGAYVSQHKAVVEVIMSRLR
VTDPDLQNYQLVYQSRSGDPSTPWLEPDINDAIRVLRGCEAVLIVPLGFI
SDHMEVLWDLDNESMQTARECGLFAIRTPTPGTHPLYISGMVDLIVERLE
GVPRSARPAMTDLGPWFDVCQPGCCKNSRSGFKPAYGGVAP
>TW743 hemL, glutamate-1-semialdehyde 2,1-aminomutase
MRTNFEWFEEAKRFIPGGVNSPVRAYAAVGGTPRFLAKAQGAYVTDIEGR
EYVDLVSSWGPLILGHAHPKVIDAVINTAHRGMSYGAPTTLEVELAELVC
NRICNAQGIKPVERLRLVSTGTESCMTAIRLARCFTGRDLIVKFSGHYHG
HADPFLIDAGSGLVGHPSSGGVPESVAKNTLVVPYNDLAVLEYLFEAYPN
QIACIITEACPANMGVIPPDPGFNARVADLGHSHGALIIFDEVITGFRVG
SGGFWALETSLASQQPTQAVSEGSVSDSAYSAYVPDLFTFAKVLGGGLPI
GAIGGRAEIMDLLSPSGPVYQAGTLSGNPLATAAGLATLRLADSNIYEHM
NRVARALINEIQSAFHDAGVPCTVQSAGNLFGISFSAIAPRDFTQATSQE
HWRYSNFFHSMLNSGVLLPPSVYEAWFVSAAFDDRAIERVVNALPDAVRA
AGSAPARPKGFEPPTF
>TW567 ilvB, acetolactate synthase
MVRISGAQAVIKSLEELGIDLVFGIPGGAILEVYNSLFSSSIRHILVRHE
QGAGHAAEGYACSSGRLGVCLATSGPGATNLVTAIADAYMDSVPILAITG
QVYSHLLGSDAFQESDIIGITMPITKHAFSVKRATEIPAAIFAGAKIATT
GRPGPVLIDITKDAQQDEFDFMWPPKSIDLSGYSVAQNIPDTLAQFADGF
FDMLSGSIRPVIYAGGGTVRSGASEELIRFAEGFGIPVVTTLTARGVLPD
SNRLNLGMPGMHGTVAAILALQKSDLLIALGTRFDDRVTGRLDSFAQNAR
VVHVDIDPAEIGKNRRPDLFVIGDVKEVLGYINSHSENRTTGDLTAWWRS
LEKMRQIYPLVFPQKSSDGNLSPGYVIKRLGELSGPDAIYATGVGQHQMW
ASQAISFSRPNSFLTSGGAGTMGYAVPAAMGAKAANPEKIVWAIDGDGCF
QMTNQELATCSVNGLPIKVAVINNRSLGMVRQWQGLFYNKRYSQTDLNTG
DAYIPDFCKLAESYSCASCRVSSVDEVDNAIEFALAINDRPVVIDFVVCK
DSMVWPMVPQGLGNSHLKYLQDVSPVWHDNE
>TW565 ilvC, ketol-acid reductoisomerase
MSEIGTRVYTECDADLSLIQNVLVAVIGYGSQGHAQALNLRDSGVNVVIG
LKENSASRKSAQDSGFEVLLPQEAAKKAQLIALLVPDPAQRDVYESAIKH
NLSEGDALLFSHGFNIRYGYITPPDGVDVLMVAPKGPGHMVRREYLDNRG
TPAVFAIEKDASGRCFDLALSYAKGIGALRAGAIQTTFTEETETDLFGEQ
AVLCGGLEQLIQYGYETLVEAGYQPEVAYFEVLHELKLIIDLIVEGGLSK
SRWSISDTAEYGSYVSGPRVIDKHVKENMKKILGEIRSGEFANRFIKDQD
SGANEFTQLREIAARHPIEEVGARLRALFSWSK
>TW564 ilvE, branched-chain amino acid aminotransferase
MSAKNYKKTLLVNPISQDELQKRLSAPGFGSVFSEHMVSADWHRDLGWHD
YRVEPYGPISLAPSAMVFHYGQEIFEGLKIFRHSQDSSVRAFRPLENAKR
FQKSSERIALPVLPVEDFLQSLREWVMVDGRWVPNAPSCVYARPFMIATE
EALGLRATCSARYTLICCPVGDLFGQIRPIKVRVSSKYSRASRGGTGSVK
FGGNYAASILPQVEAGNNGFDQVLFLDSASYKNIEELSASNIFFVLSSKT
LITPSLDGTILPGVTRDSIIRIAEDLGFVVEQRQISLDEVTHLFSQDKVT
EMFCCGTAASVTPIGSVSFDGGTLGSGQAGPVTMLLREYLRDIQFGNRPD
KYNWMVNLEDT
>TW301 lipA, lipoic acid synthetase
MNDSGNSSKVNVRPPSAGLGAPSPGKRKMLRLEVRNSQVPIERKPSWIRA
RATIGTEYRKVQERVKKQNLRTVCQEAGCPNIYECWEDREATFLIGGSQC
TRRCDFCQIDTGKPAELDLDEPKRVGQSVAQMKLRYATVTGVARDDLPDG
GVWLYAETIREIHKQCPGSGVEILIPDFNGKPELLQQIFEAQPEVYAHNI
ETVPRIFRRIRPAFRYDRSLDVISQGQKAGMITKSNLILGMGETGEEVTQ
ALRDLKSAGCDIVTITQYLRPSPRHLPVARWVKPQEFIEYKEQAKEIGFS
GVLAGPLVRSSYRAGKLWAQSVKAKMVEIPERVRKLINEIEMQETSFRQA
V
>TW302 lipB, lipoate-protein ligase B
MYSIRVLAIECIRLAPEYLPFEEGWRMQQELHKKITESQTNKNRQASMIF
CEHEPVYTAGARTRSWEMPQNEKVIRVGRGGKITWHGPGQLVGYPILSLG
ATPDVLRYVRQIEEGLINALQSVGINGFRIAGRSGVWVRNGVSDEKVAAI
GVRVQKNVTLHGFALNCSNDLAPFEKIVPCGISDAGVTTISRILKRTITP
KEILDSVFNSICSALEYINTCRGNV
>TW080 menA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase
MALEKRRRKKKRSLILPWLLASRPATLIVSLSAVSLGWGAALLTVTGRKA
SLLLVALAALTAVLLQIGANYINDYGDGIRGADSNRSHASRRLTASGANP
FSVLTTGLSFLIAAAGSGLIAVILTQRWQLILVGVFSIAAAYLYTAGPFP
YAYFGLGELSVFIFFGPVTVIGTVFLLSGIVTLSSFLVAVVAGSWSAAIL
LMNNLRDHESDMQSNKRTFSVLFGVLIARIVCIALIAVPYIVVAILLIEL
PFIGYVFLTLLLSAPIVIILATAVTSKEFAIAFRLGIICLIPFAIFFTWG
LAS
>TW120 menB, naphthoate synthase
MGESKGAPTFDTLQHVLLSELFDPDLWVAHEGFEACDVTYHTAPGVARIA
FNRPEIRNAFRPETVDQLYAALDHARVSDKIGAVLLTGNGPSPRDGIRAF
CAGGDQKTRRRDGYAYSDSHRSSRMHILEVQRLIRFMPKPVIALVNGWAA
GGGHSLHVVCDLSIASLEHAKFKQTDATVASFDSGFGSAYFARQVGQKFA
REVCFLAAEYDAKTALEKGAVNAVVAHEYLEQTGYEWARRILEQSPTSIR
MFKYALNAVDDGLVGQQIFAGEATRLAYATDESKEGRDAFLEKRRPDWSS
FPWSF
>TW078 menD, putative menaquinone biosynthesis protein MenD
MTCASGIAFCLLNLLAERGVRDIVVAPGARSQALALAAVALERAGLVRLT
VRIDERVAAFTAFGMAKALDSPAVVITTSGSAVANLYPAVVEASHSFVPL
IVITADRPRELHGKRSNQTMNQEKFFSHWVRFFCHIEQDVPGERVIDSAL
QAALGVSSLRGAGPGPVHINVAFDNPLSCAHAVQPGDNKGSALKHKKVLR
SKRETLVLRKDDPPTVIIAGTGSGRRPADIACATGWPLVAEISSGSRFGP
FLIKNYRNWLTENSLDIRRAIVFGHPTLSSEIPTFLTKRNIDTIVVAPFG
REFYNPSGTARPVANVLVDEDSFSGIPLGAAKFASASAGCISQDVISSDR
PRGHRVTRQQLVSEIWNITKEDEILFFGSSQLIRVADSILPGKRVTVFAN
RGLSGIDGNLSTAAGIAIATNRTTRVLVGDLTGVHDIGALLIPLMEAKYR
LQIVIGNDFGGGIFDTLEVHATPSDYKRVLYVPCRVDFRLVSHAFGWKYT
FCPDPNSLRKALKSRIFPHLLEVHLAV
>TW409 metK, S-adenosylmethionine synthetase
MILTSESVTEGHPDKLCDQISDAILDGVICKDKNARAGIETIAGNGVVHV
FGEVSNPDSVDIPGIIRKTILDIGYTSEDAGIDGNTCSIQESITSQSKEI
ADAVNFSLEYRNQQGDLGRNSFSQQGSGDQGSVFGYACRETPEMMPLPIT
IAHKLAYSLAFVRKEKILPYLLPDGKSQVTLGYDSANRPKTLETVVISAQ
HEDSVDLDKLRFDILERVVRPVISATGLDCSKATFLINPAGRFVTGGPSA
DSGLTGRKIVVDTYGCAAKHGGGALSGKDPSKLDRFASYMARWVAKHVVA
ADFAESIEVQISYAIGKAHPVAFNIDTHGTSTIALDKLKCAILKVFDFRP
AAVIDSLDLKRPIYQKTAAYGHFGRDIFTWERICPDKLNALLGAV
>TW296 nadD, nicotinate-nucleotide adenylyltransferase
MGGTFDPIHHGHLVVASEVASRFCLDEVIFVPTGRPPHKKEVSDPWHRYL
MAVIATASNQRFSVSKIDIERTGPTFTVDTLRELREQLQSSDLFFITGTD
ALARIFSWKDADTLWSLAHFVAVSRPGHEVVDIPNDRISFLEVPAMAISS
SNCRERVRSGLPIWYLVPEGVVQYIAKHGLYRSLYG
>TW365 nadE, NH(3)-dependent NAD(+) synthetase
MCCDISKTLCVKPFIDPEEEISHRVSFLADYLRHSRASGYVLGISGGQDS
ALAGRLCQIAVESVRSIGFDATLWAIRLPYGQQFDESDAQTAMQFISPDE
ELSFDIRSATDNLCVDLNRSLGSKISDFNRGNIKARLRMVVQYAVAAHHD
ALVVGTDHAAEAVTGFFTKFGDGAADILPLYGLTKGQGRALLKALGACDS
IIEKVPTADLLDDLPCLPDETELGLQYRDIDAFLEGKPVSEDITMAITER
YKSTLHKRMPPITPHSTWWRK
>TW510 panB, 3-methyl-2-oxobutanoate hydroxymethyltransferase
MSRKPSPTRRTRIHRFHKGSCGRKLVGLTCYDFSTARVLSDCELDFLLVG
DSASGVIYGYENTGSVCLDEIIYLAAGVVRGAPNSFIIVDLPFGTYEKSD
ELAVETAIEVIKRTGASAVKLEGGARMACRISAIVRAGVPVMGHIGFTPQ
TINALGGYKIQGRDNADLIYLDAQAVEQAGAFAVVMEMVTEDLAKTITSE
IKIATIGVGAGRYTDGQLLVINDLIGLSEKKITFAPRYASIDNTVASCVK
LWRKDVLEGNFPQKDHIPA
>TW073 panC, pantoate--beta-alanine ligase
MNLKLASSPHELRTCLAGRAFVLVPTMGALHEGHIWLVDMARRCNLPVVV
SIFVNPLQFDDSLDLDTYPRTLEQDLEKLEGKAFAVYSPSVETMYPNGLD
SIRIDPGPIGRILEGAIRPGFFDGILTIVAKLLLQTAPERVFFSKKDAQQ
AFLVRRMVRELAFPVRVEVTGFLRDKFSLPYSSRNRKLGVDAREKAQRLS
QGLLSVVNNGPLTVRDCIDKITDLANSIGVDLGYAQILDENFCEIASDRM
VTRAFHSEACIGLNTPLFLLAARVHGVRVVDNVDLVVV
>TW709 ribA, GTP cyclohydrolase II
MMGNMDKGLDSQKQETARSCRFEVETNLPTKFGTLRVRGYRDIKNNEHIA
LITKQIKSEDVLLRIHSECITGEVFMSLKCDCHGQLHKALERISAEGGLV
IYMRGHEGRGIGILNKLRAYRLQEQGLDTFDSNVKLGLPVDARDYGPAAE
ILHDLGVRSVRLLSNNPDKQLQLEQSGIRVTGVLPWQVGLGKCNHEYLKV
KRDKMGHKIEL
>TW708 ribB, 3,4-dihydroxy-2-butanone 4-phosphate synthase
MRHIPDALNALRAGRPVVVLDDKNRENEADVIMAAQFATQEWVAWIIRHT
SGFLCVPLSNQRADKLQLPSMVAANEDRFKTAYTISVDAADAAITTGISA
ADRSLTIRTLAARDSSAKHLVRPGHILPLRARDGGLLERRGHTEAAIELM
RQAQLEPVAVIAELVSDTGELLRGRALDEFIRKNNLVLVEISQIIEYMKM
SDLKDISMNLNRDCL
>TW706 ribD, riboflavin biosynthesis protein RibD
MYMRSSACTDLFVLAMHRAITIAQHGPVFDRNPQVGCVILDRDYQLISQG
WHMGSGSEHAEIMALRGAKSILSEPYAAVITLEPCSSAGQTGPCVRALLD
AGVKHVVFGVHDPESSGAKVLSEAGVKITYGVLEREVWGLCAKHILPKVR
KTPWVIAKRAQGLDGRMSAPDGSSKWITGPYARGHAHVIRSQVDAIAIGS
NTLCCDNPSLRAFHPAGHLYAKQPKVVIFSGRPRRSNTAGRGSCELGRCV
RGHEFFARDPTILSGKDLKKDMRRLYELGVRSLLLEGGPTLLSSFVREDL
VDEFYIYTAPKLLGGGYGDINIGVESISDSFAFQLNSVTRFGDNNLLIRA
IKPIQCNPDTRTYRTKKHLRD
>TW707 ribE, riboflavin synthase alpha chain
MGAHKNDIAGQITETDSVRKIGVAIPRQHLVQQPKVGDSVSVNGVCLTVR
EVHEDVFVFDISQVTADATTINVWDVGQFVNIEMPLTPSDPIGGHIVQGH
VDGVGMIEQIIDNCLRIKIPDSLSLLVVKSGSIAVDGVSLTVVNVSEQLP
STANVSGNHGKQNCANSWFEINLIPETLERTTLGGLQVGQFVNLETDVLA
RHVRRFMSLVNSFS
>TW180 ribF, riboflavin biosynthesis protein RibF [includes: riboflavin kinase]
MRVFRSFDCLGRDKRTALTIGKFDGVHLGHRRLLERIVALQNQDTSALVV
TFDRDPKTFFKKDMSFVPLCSLEQKLSLLENCNIPNCLILRFDDEFASMS
AEDFVHKVLLEKLNMSSIVIGDGFRFGARGLGDAMLLEKLARELGFYLEV
IPKIQFGKTNISSTLIRKFLSLGQAGNASSCLGRNHVCTGTVVHGKKRGR
ELGFPTANLGKDVSGFIPADGVYIGRIISDRSYPAAVSIGRNPTFGDLEF
SQIEAHALYEDISSLDLYGRRIDVEFIAHLRDTMLYKSIDSLKAAIRSDV
ERCKEYFSTTVG
>TW710 ribH, 6,7-dimethyl-8-ribityllumazine synthase
MGKDRNLSLNSPESIQSVIGDTDIKIAVIAAMWHEKIVRGLIDGATREIV
SSGSHAELFRVPGSVELVLACKKLLKTFDAAVALGVILRGETDHNTHIAR
LVLSGITDVMLALEKPIGIGVLTIDTEQQGLDRSSGDYNAGVNAARAVIR
MVRLFR
>TW384 trpE, anthranilate synthase component I
MEEDRGVFWVDYPVDLSEDFADSCFRYLFEALFYDSENCFWLDDARPLQN
RRRSAIGSGPSVSLRSGSCLDPTDVESFFSKLLDCDPQPWPLGFVGWIDY
EVGACLLGVNYPTQQDAPATGQTNLSSWICCNRAICIDYRMGLLKIISFS
KNTVDAKEWVNRASTLVEKLLMKGSIDREDYIPQAKSRHLANSKLMPRNS
FASGLQWLHTDQQYLQLIHRVLEKIMRGDVYQICLANRLTIRNSGNRSPF
SAFWALRQKSPTQYCAYIKIGPRHFVSSSPELFLALSDNILVTEPIKGTR
PRGRSPSEDSYLISELKTSEKEKAENLMIVDLMRNDFSKICSSVEVDYMY
RVRTYKGLHQLVSRVSGILRPGRGFFDILCATFPAGSVTGAPKIAAVKSI
YDLERARRGVYSGAFGYISGDGKNICFAMSIRSAVFCNGEVSIGSGGGVV
FDSDPEFELAETKLKVAAMIDAILGR