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# Idiomarina loihiensis L2TR, L2TR

>IL0049 Riboflavin-specific deaminase
MSEKFMLEALNISKQALPHCEPNPPVGCVLVKDGEVISKGFTQAIGGSHA
EVEALNAHSGDLSGVTAYVTLEPCSFVGRTAACASTLLASGIKHVIIAML
DPDIRNNGKGAEILTAGGVKVEVGLCAELVAQFLSPYLAKS
>IL2394 Glutathione synthase
MRDIVILHENEEWLVPLRAEFEKRGVQAKEWFLDTGVIPFSELPEDAVYY
NRMSASSHTRGHRFAPELTRMALTWLENSNRTVVNGTRVLALEVCKLSQY
AALQKAGLNVPKTQAVVGKELLTEAAEKFAEWPLILKPNRGGKGLGVIKF
DDVAGLKSYINSDDYEEPLDGIWLLQEYIQPKQPHITRSEFVGQKFVYAV
NVNTEQGFELCPADVCSVDDAFCPTSEAPADGNQPNKFTITQRFNDHEII
FALEAFLKANDIDVAGIEFIEDAKGELYVYDVNTNTNYNQSAEREAGVKK
TGMGALADYLISLAQ
>IL2102 5-formyltetrahydrofolate cyclo-ligase family protein
MTRHNLRRKLQQIRRNLPAEQQQTAAREVANRLQQRLSHLQPEQTTVAVY
KSFDGELPTFPVIETLWQLGFNTVLPVLHPFAKGHLLFLRYTPDTPMTLN
KYGIQEPELNVQNMVPLSNIQILLMPLVGFDQNGNRLGMGGGYYDRTLAQ
WHNGNRPNLFPIGLSYNQQQVEHIPVESWDIPLPEVITPAKHWRF
>IL0485 S-adenosylhomocysteine hydrolase
MSAENSQDYKVADISLAEWGRKEIAIAESEMPALMTIRRKYADSKPLAGA
RIIGCIHMTIQTAVLIETLLELGAEVRWSSCNIFSTQDHAAAAMAAAGVP
VFAWKGETEEEYDWCLKQTCHKDGELWDANMILDDGGDLTLMIHDEFPQM
LEKVHGITEETTTGVHRLLDMLEKGTLKVPAINVNDAVTKSKNDNKYGCR
HSLNDAIKRSTDHLLSGKKALVVGYGDVGKGSAASLRQEGMIVKISEIDP
ICAMQACMDGFEVVSPYLEGKNNGTGDNINKDLLSNTDLIVTTTGNMDVC
DRYMLAALKPTALVCNIGHFDNEIDTAFMRKNWRWEEIKPQVHKIYRSDD
DNDYLILLAEGRLVNLGNATGHPSRIMDGSFANQVLAQIHLFEQKFADME
IKQQEEYLRVEVLPKQLDEEVARYMVQGFGGVITKLTADQANYIHVDVEG
PFKTDEYRY
>IL1569 2-hydroxyacid dehydrogenase
MKAVILDAETLGKGIDLSAIEKSVDELVLYDSTTTEQLNERINDAEIVIT
NKVVINEQALESAEQLKLICVLATGMNNIDLAAAEKLNIPVRNVEAYGTQ
SVVQHTLMMMLSLATKQPVMQKRVAAGDWQSSSMFCLLDPSIIQLAGKKL
VIVGSGELGQEVKTMAEALGMHVEFSARPGKKDDPRPSLNELLPSADVIS
FHCPLTNDTKNLLNADNLELCKKDALIINNARGGVINEQDVTEALRAGKI
GGVAADVLPQEPPKDGNPLLDAMNEGLNLIVTPHNAWTSPEARQRIVELT
AENIQSTQGKN
>IL1752 Anthranilate synthase component II
MTQSARIVLIDNVDSFSYNLVDELRQLGFPLVVYRNQLAAADVIEQLESY
SGPQLVCLSPGPGHPANAGNLMEVIRYCGGRIPMLGICLGFQALIEHAGG
RVDTCGEIVHGKTAKIDTVPHPVFVSATDNNQCVVARYHSLSGYDLPSTV
SIIASLDGPDGSIPMAAEFFGKEENNTNAIGFQFHPESLLTPKGKQLLSN
SIQYLLTGAKP
>IL1980 Uncharacterized Fe-S oxidoreductase
MTSPLTLPPLSLYIHIPWCIQKCPYCDFNSHKLTGDVPEASYVGRLLEDL
RADIDWVQGREIQSIFIGGGTPSVLSAKAIQQLMDGVRSIVALSPDCEVT
MEANPGTFETEKFSAFVAAGINRLSIGVQSLQEHQLQRLGRIHNPQQAIN
AAAHASELPLSSFNLDLMHGLPDQTVEMALDDLRQIIALNPPHISWYQLT
IEPNTLFASQPPELPDDDTLWEIYQQGHKLLEAAGYSQYEVSAYAKPGHQ
SRHNRNYWQYGDYLGIGCGAHSKVTLPQQNKILRCEKVKHPKGYLDLTKP
LRYQLKEVAVEDRLFEFFMNQFRLLEPVSKSNFEQTTALSAEVASKQLTE
AKTLELVTEDELNWQLTQRGHRFLNSVLDTLLD
>IL1620 Uncharacterized conserved protein
MMAKNTLLKDNEEAQDSLGEDDAFASEFIDGLQEVNYQLMMNFGQEVAAN
LFIFDLWVRNGDRTLSMKGGNPNVFYQPAEQRFWALDHNLAFDDSFEFYD
FTKDHLGRDAWIQQRDLLSRQLYQDRASNCLRQLDEIFSLVPDEWDLTDD
FMEQIRLTLGLINHDNFWERI
>IL0171 Uncharacterized conserved secreted protein
MPYRKILAFTVLFTLAQAASAQDSWGDDEWESDWGTEQDQGIDVYGYVEA
AIGGRFESSPYHKRLSIAEPRLQLGFDERWQDIAWTAKADGWYDGFDETW
HGQIRELNAQFTVFDNTDIKIGRQVLTWGTGDYLFLNDLFPKDWQSFFVG
RDQEYLKAPSDALRITSYFDWFNLDFVWSPEFDPDNYIRGERISYFNPLT
QQLTGDDPSIQFVEPTRDEYALRLFRNHEGVEYAVYGYDGFTKSPEAVTD
NFQPTFGRLTVVGASVRMPLGPGLVNTEVANYNRHDAEDHWRALVGYEQE
LWTRFTGGFQAYVEKGDNQTRTVFTTRLTWRDERDDLNLSLFAFVSPNQS
DGYLRPTFDYRIDDNWSLSGGFNLFFRERPETFFGQFTENNNAYLRMRYA
F
>IL0512 Dinucleotide-utilizing enzyme of HesA/MoeB/ThiF family
MSEEVPDQRFGGVSRVYGQASLTQFQQLHIVVAGLGGVGSWAVEALARTG
IGKLTLIDLDDVCVTNINRQLPATDDTIGQLKSEVLAQRVKSINPNCEVR
VIDDYLLPENFEEYLTGADAVLDAIDSVNTKSALVAWCKRRKLRIVVCGG
AGGQIDPGMIRVGDLAKAKQDPLLAKVRSQLRRDYGFSKNPKRKWGVDCV
YSEEQLRYPIISGEQEGEVTLQKPGSGSMRMDCSSGFGAAMVVTCSFAMQ
ATAILLKRLSHLT
>IL1808 Beta-lactamase class D (N-terminal domain) fused to uncharacterized conserved domain
MKISLLVLFILSFAVPVCAETQERSDWGSVFEKYEAEGTIVVVDGRDSEQ
TTLVFDKERAAKRFSPASTFKIPHTLFALDAGVVQDEFEVFKWDGVERSF
AGHNSDQNLRSAIRNSTVWVYQQFAEDIGAEKAKSYLKRIDYGNADPSDD
VRNYWLDGQLAISANEQIAFLQRLYRNELPFAVEHQRLIKDLMIVEAERN
WILRAKTGWEGRFGWWVGWVEWPEGSVFFALNIDTPNRMADLAKREKITR
EILTSIDALPSRTAEKNEVDSETTVAVVDTNLYLLGTFDGNTADKVISTL
EAHPGVQRIVFTANGGSVNDRDTLRLGRYIRQKGLHTHLISNGVAASGGV
SLFLAGVKRSVGQGAHVGVHSWAQCSDSAEASHCKPATDFPRHDTAHDLH
RIYTDEMLGADDFYWFSIKSASHNSIHWLSRDELLEFQVVNNELEDTLEI
PFADKFRKEYESTCHNCPRASD
>IL0939 FAD-binding oxidoreductase, UbiH/Coq6 family
MKQLSVLINGGGMVGASAALALAQHGANVTLLEPFPPGKDSGTDPDWDLR
ISSVNNSNWEWLLELGIGVCVRQQRVFDYQKLSVTSQSGHNLSFQANEAG
LSKLGVMVENNALQLALWTKLRSLKNVDLREGETLDKLNAGTKTVVLSQG
DTLSYDLLLGCDGANSIVAQLAGFHYRGWDYEQRCLLANVSLEKPIEPET
WEVFRPQGPYALLPLTEQQACLIDYGLRDNINSLQRDKAGLEAYLRETFS
PHIGNFRVLKSASFALQRKHAAHYVKEGSIVLLGDAAHSIHPMAGQGVNL
GFADVRCLVEVLQENTPSVALDKYEKTRQGENAKMMRMMDAIQFGWRSRN
PVMQFATAASLKVAAFPWVKRWLLKQAVGE
>IL0950 Nicotinic acid mononucleotide adenylyltransferase
MIRAIFGGTFDPIHNGHLQTAAALVKELGISTLALMPSAVPPHRPQPDAS
PEQRLDMVKLASQYHKAFTVEDWELRQDRPSFTANTLSEFKTQFPDDTLL
FVMGMDSLMSLHRWHHWCQLIECAHLVVMPRAGVPFNPKNDELKEFISVH
LTRDKNALNTQSQGLLYIAETPMVDVSATELRKQLQQREKNLPLPSNVYN
YIRQHQLYL
>IL2160 RimK-like domain (C-terminal) fused to uncharacterized conserved domain
MQQHVHLIIDNAADWQPYYPSQSLLTASEYLQSAHLQSRYHVLNLCNDLS
YLSTGYYVSLLAEARGQRVMPSVATINDLTNFSHYQLLINTADRSLTKYL
QNRDEKSLSLLICFGLCEQPELASFARQIFERYPCPILKVELEFNGRWHI
NKLTSGALNQLTDEQQSFFGNSLDHFSKRVWRKARTRKEYRFDLAILYNP
DEAIPTSDKKALSLFIKAAKEADIEAELITANDFNRLLEFDALFIRETTR
INHYTYHFAKKAEANGMVVIDHPDSIVKCANKVFLKELLDKHKVATPKTE
LLLSQSDIDYEAIGERLGYPVVLKIPDGSFSIGVEKAEDLAQFKQVATEL
FKQSTILLAQEYMRTDYDWRIGVLNNRPIYACQYFMARNHWQIYNHSESS
SRGKSGSFATLGVHQAPKDVVRLALQATRLIGDGLYGVDIKQTPQGPVVI
EINDNPSIESGVEDKHLGYELYRLIMADFGRRLDEY
>IL0124 Phosphopantetheinyl transferase related enzyme
MVIGYRLYNEAASKKQVSAAAKDLLLRLVKKYWPATEPQRISIENSDSGA
PLLNVDGCPVYCSLSHKSGCIAAAYSTTSTIGIDLENVHTRKDYHRIRDY
YKDGFLAGSTLTKSDFFHHWTLAEAFAKASGVPLLSVLERPLHRQKHSAK
YFQIEPFLLCAYQSDSSEREDAVLLYQLDNDNQWQ
>IL0724 Pterin-4a-carbinolamine dehydratase
MSNLENARCEACHADAPQVSDEELKELMREIPDWTPVTNDNVMMLQREFK
FKNFKQALAFTNRVGDLAEEEKHHPELVTEWGKVTVTWWTHAINGLHKND
FIMAAKTDSVVDA
>IL1256 Uncharacterized conserved protein
MQLFVNDLTVIDCSYLCPERGIVGESWIVDIVLDGALNEQSMVLDFGRVK
KQVKAIIDNSVDHKLVVPAEHSYTKVTHNSDDSANWVDFLRPEQGSIHLF
CPADAFAFIDADVVSMETVTDYLKAVIKRELPVNVEGLQLFLRPENIDGF
YYHYTHGLKKHDGNCQRIAHGHRSKIQIRLDNIRQPVLEKEWSDKWEDIY
LGTTEDVRSKKELTLSEAATSATSDSTHTYYSYVADQGLFELIVPNAENF
VIETDSTVECIADFLAAEIKSKHAGQAVEVRAFEGVGKGAIAYA
>IL0106 N-terminal Zn-ribbon domain fused to SAM-dependent methyltransferase
MQCTLCSSISQPFCADKKRQYFRCTECDLIFADPDTLLSQTEEKLIYDYH
ENGPNDIGYCEFLNHLTTPLLDKLSPGMKGLDFGSGPGPTLNLMLEEQGM
KMSVYDIYYAPDTGQLSRQYDFVTCTEVAEHFREPDKSWAQLIGLVKPGG
WLGVMTCMFTKETADDFNLWSYKGDPTHISFYTPKTIQWIARHFRLELEI
VNDRVILFRKNKVAL
>IL1666 abgT_1, Probable p-aminobenzoyl-glutamate transporter
MQSPNNDYNATSKRGWFTRFLDGVEWLGNLLPHPITLFAVFCLFIIFISG
IAAYFGVSAVDPRDGETVIKAVSLLNAEGIQRIVTNLVTNFTGFTPLGTV
LVALLGVGVAERSGLISAAMRGLVMKAPPRLVTVTIVFAGVISNTAAELG
YVVLVPLAAMIFYGLGRHPLAGLSAAFAGVSAGYSANLLIGTVDPLLSGI
TEEAAKIIDPAYTVGAEANWYFMMVSTFLIAIMGALITDKIVEPKLGKYN
KDEASIDLSDQSSMDPLNKQEKRGLIYAGLSVLVLAGILALTVVPEWGIL
RHPETGDVKGSPFLKGVVVYIFFFFAIPGFVYGRTVETMRNDRDVIDAMS
HSMSTMGMYIVLVFFAAQFVNFFKWTNFGTIFAINGAEFLTNIGMTGPII
FLFFIMVCGFVNLMLGSASAQWAITAPIFVPMLMLVGYSPEVIQAAYRIG
DSVTNVITPMMSYFGLILAVAARYKKDLGIGTLVAMMLPYSMFFFVGWSV
LFFLWVFVFGFPVGPAAPTYYN
>IL1671 abgT_2, Probable p-aminobenzoyl-glutamate transporter
MAQSPQPDRSQKDKPDSLLNRLLDGVEKVGNKLPDPAVMFFGLLIIVWVM
SWLLSGVSFDEKHPLTGDSIGVINLLSGTEFAAFLANMVDTFMGFAPPGG
CAGRYAGCRCSRTLGLY
>IL1672 abgT_3, Probable p-aminobenzoyl-glutamate transporter
MLGVGVAERSGFINVAIKLMLNVTPKMLLTPVLILVAIVSHTAVDAGYVL
VIPLGGVIFYAAGRHPLAGIAAAFAGVSGGFSANFVPSAIDPLLQGFTES
AAQIIDADMQLNPLNNYYFTAASSIVVVAIGWFLTDKVVEPRLRGAEIDG
DAEDMPALDEVSPRDRKAFYAGVITMAVGLTLLYFSATAENTPLADPTTG
ELASYSAPLMGMIVPLIFLLFIIPGIVHGYVSGNFTNSQDVIGAMTKSME
GMAYYMVMAFFCALFIKAFGDSQLGTLISVKGANFLASLELSGGVTMVGI
VFLVAFINLFVGSASAKWALISPIFVPMLMQLGYSPDLTQAAYRVGDSSS
NIITPLLPYFPLVVLYCQRYVKGTGIGTLVAMMLPYTVALLILWSAFLIL
YWTLGFPLGIQANYVYPAG
>IL0456 ampE, Membrane protein required for beta-lactamase induction
MVLIALLIALSVERLYHSPAFLHWSFFLERWQHWSAARLTNEKWKSEPLQ
LVRLLVPALAVGFLVVLLDNLMVTFIVSILSLLLAMNCEPARKSYKAYLK
AANRGDEQQVNEHQHALTEFAGQHQPKQLSDSLIWINYRQYIAVMFYFVL
FGSFGALVYASLRYAEKQISEPESTKLWQQFMWFADWVPARLAGFGLLIV
GHFSRAFPVWVKHSLNPQADPDKLLFNVASKAEDIPQHPDDRTEHIACQL
RLMRRQQIFWVCVIAALTLTGWVN
>IL1868 apbA, 2-dehydropantoate 2-reductase
MTKANLNWVVLGPGAIGGLIAGALLEHGQSVSVLPRKNRTREINWQVTHK
QFKADYSAPVITQLLAENTVFVIAVKAFDVIQALQRITTLRGFNKAMPII
ISHNGMVELPEPLKELNLHPLVTTHGAVRSRNENADLCIEHRGAGRSWLE
VDPAVRNQPTDFDPGLVLQQAFPPLTLEQDLSQRRWLKFVINCVINPLTA
VHQCANGELLKGSWQAQVYSLVAEAVAVANSQNVSLTTEECYKEVLLVAK
ETALNHSSMLQDIQQQRRTEIQQLTGYLINAGKTAGVATPTHQQLLNEFQ
QRYSG
>IL1044 apbE, Thiamine biosynthesis lipoprotein ApbE
MMLSKLSIAKIWLALLGLAFLVSCSDSPEKISFSGKTMGTTYSVTVYSKD
PRHNKEEIQKKVDIVLKRVNAQMSTYDPESELSQFNQFKSTQPMVISRDL
ERVVNRGLEIAEETEGALDITVGPLVNLWGFGPQARPEKEPSEEELNAVR
EKTGYQKLRVENHQLIKDNPELYVDLSTIAKGYGVDRVAHLLDQLRIKQY
LVEIGGEVIAKGGKPDEALWRLAIEKPVSTERAVQRVVQFKDGALATSGD
YRNYYEEDGKRYSHIIDPVTGAPVQHNLVSTSVYAEDTMSADAYATALFV
MGTEKAKSFAKKHNMAVMLIYKTDDGFEEYMSEAFKPLLAEQ
>IL1325 bioA, Adenosylmethionine-8-amino-7-oxononanoateaminotr ansferase
MSKSDIEFDRQHIWHPYTSMLNPLPAYKVESAKGCRLTLDTGHEVVDGMS
SWWAVIHGYRNPRLDAVAHRQIDKMSHVMFGGITHQPAIDLARRLIELTP
EPLQRVFIADSGSVSVEVAIKMALQFWLAQERPEKHRLLTIKGGYHGDTF
KAMSVCDPVNGMHHLFNRAINSQLFAEAPRLTPDDDWAETAGDELRHWFE
QHHHELAAVILEPVVQGAGGMRFYHPEYLRLIRQLCDDFDVLLIADEIAT
GFGRTGKLFACEHAGITPDVLCVGKALTGGYMTLAATLTTKQVAETIGHG
PGGGALMHGPTFMGNPLACAVAAESLAIIAEGKWQQQVAEIEAQLKQQLL
PLAECDAVKDARVFGAIGVLEMHHPIDVAIAQKRFVELGVWIRPFGRLLY
IMPPYVISTNELSRLTVAMKDYVETQSSIKA
>IL1324 bioB, Biotin synthase
MPQIRNDWTIEEVQNLLQMPLNDLVFEAQTVHRQHFNPNEVQVSTLLSIK
TGACPEDCKYCPQSAHYHTGLDRERLMAVESVLAEAQAAKEKGASRFCMG
AAWRNPKDRDMPYVIEMIKGVKALGLESCMTLGMLSNEQAKMLQQAGLDY
YNHNLDTSPEFYGDIITTRTYQDRLNTLNNVRDAGMKVCAGGIVGMGESV
TDRASLLVQLANLPKHPESVPINMLVKVEGTPFAKLEDLDNFEFVRTVAV
ARILMPASHVRLSAGREDMNDEMQALCFLAGANSIFYGEKLLTTANPEAD
ADLRLFERLGIKPEQRDGYDDEVHTAVIEDAIKEQQNPVRYYDAS
>IL1321 bioD, Dethiobiotin synthetase
MNTYFIAGTDTDAGKTVAACAFVQYLVKQSQQVAVMKPVASGCHWQNGQL
VNEDALNLMRQSNTSFDYDRVNPYTFEAAIAPHIAAADSGVVIDKERLLK
AVDWFHERPIDSLVIEGAGGWQLPLASGLRMPQVVKEVNAKVVLVVGLKL
GCLNHALLSLQSIKQEGCDVAGWIAVQTGPEPMPRQAENLASLRELLDEK
ELASIPYLPGWTEEDLSIYFHK
>IL1323 bioF, 7-keto-8-aminopelargonate synthetase
MLGYEQRLNERKDSSLFRSRKVRSSDAHWQLDFSTNDYLGLSQHPDIKRA
FKQAIDTWGVGSTGSPLLSGYSKVHQELEELLAEWMNKPRALLFNSGFAA
NHGVLTTLVDKQQKLFADKLVHASIIDGMQHGEGRFKRFPHNQPEPLIGK
ASPGDWLVTEGVFSMDGDVCDLNHLAYLKQRYGLKIMLDDAHGIAAYGAE
GKGSLVADSAVADVITGTFGKALGVGGAFVCADDDEIESLIQFCRDYIYS
TAMPPAQAAAIKASVEIVRSAEGDDRRGRLAERIQYFREQLKQRGLKTIE
SNSAIQTWLFNSDEDALNMATELQAQGYLCSVIRPPTVPAGSSRIRFSLT
SEMSKPELAQFWSRVDRILSQL
>IL2003 birA, Biotin operon repressor/biotin--protein ligase fusion protein
MKQAERLDQLITLLANGEFHSGQAIGESLAISRAAVNQHIHKLEELGLEL
FSVTGRGYKLAWPIELLQARVIENESPEKWRQSPEFEVKSVVDSSNDRVK
ELAKEGPLEAGFSIFAEAQTAGRGRRGKKWISPFGNNLYFSVYWPLDEGI
HGAMGLSLAAGVALAECFTDLGIEGVSVKWPNDVYIRGKKVTGILVDLET
SPEGAAHSIIGIGINLTMPEHVGASIDQAWTDLNSELPQPMSRNHIAAQV
RASVLSALQQYEQHGLAAFQQSWRRYDCFLDKPVKLIMGQRVCLGTCRGI
DENGALLVEDEQGVRRYFGGEVSLRAQDATN
>IL0487 cbiB, Cobalamin biosynthesis membrane protein
MNTELLTDIILSPVALALLALLAERWFPWPEQWHPFAVLRLMAAYMSGKV
NRPNRPVGQQRLAGFLAWLTMSLLVLLPAAIVFAGAEVSLAIGWLILLVS
LRQQPVSHAVKLADSHLQRGRKNAARAWLSRITWRDCDLLSEHGIAKTSI
ELRATSILEHRFTPLLFWFVGGPLAALGVRTLSELTQVWPVAQAKYRHFG
LATHWLHTITHFLPSFILALAARFMALFQRNKFRLQPLKRNPLFSTILLS
WLQSFSYCHRVSLGGPIQVQGIRIARQRFDGRPAELLIPRASRWQRQWQG
FFIACLLIALFALFIYRP
>IL0271 coaD, Phosphopantetheine adenylyltransferase
MHRRAIYPGTFDPITNGHADLIERAANLFSEIVVGIAESPSKKPLFSLEE
RVLLAQQVTENLDNVTVVGFSGLLVNFAKEYEATVLIRGLRAVSDFEYEF
QLANMNRRLAPNLESVFLTPAEENSFISSSLVKEVALHGGDVSGFTDARV
ASALEQKFSGKRPGKS
>IL0449 coaE, Dephospho-CoA kinase
MTYVVGVTGGIGSGKSAATAEFEKLGITVIDADIVSRQVVMPGTPCLRAI
AEHFGRDLLTDKGELDRKALRQKVFSDPAEKDWLNSLLHPAIREEILTQL
EQASSPYVILSAPLLLENNLDKYCQRVLVVDVPEELQLQRTIQRDESPKE
EVEAIMKAQLSRKARLRKADDILNNESSIDQLRRQVNQLHQRYLAATVAQ
EE
>IL0239 dfp, Phosphopantothenoylcysteinesynthetase/decarboxyl ase
MAQLQNKHILLGITGGIAAYKAPDLVRRLREQGAEVRVVLTAGAKAFVTP
LSLQAVSGFTVSDDLLDPTAEAAMSHIELARWADLILIAPATANTIARIA
HGFADDLLSTLVLASKAPLAIAPAMNQQMWAATAVQENIETLLSRGVQMI
GPESGEQACGDVGYGRMSDPTEIVQALIKKAPEAKQDWQGKTFIITAGPT
REAIDPVRYISNHSSGKMGYALAEAAAHAGAKVILVSGPTQLPTPTGVQR
VDVETTEQMLNAVQQQLPNCDVFIGCAAVSDYRVAEVASQKIKKEQNNQP
PQLKLVQNPDILQQVASSEKPPFTVGFAAETENLKANALRKLERKQLQMI
VANDVSQVGLGFNSDSNNAIILSKDSEQSLPTMSKHDMAIAIIDAIAKRY
FNTTAN
>IL2138 dxs, Deoxyxylulose-5-phosphate synthase
MTQQYPLLDKINSPADLRRLPRTQLPELCAEIRQFLLTSVSQSSGHLASG
LGTVELTVALHYVYHTPEDKLVWDVGHQAYPHKILTGRKQRLHSIRQKDG
LHPFPWREESEYDVLSVGHSSTSISAALGMAVAAQRQSLRQKVVSIIGDG
AMTAGMAFEAMNHAGDIKPDMLVVLNDNDMSISENVGALNHHFARLLSGR
FYTSLREGSKKLLSPLPHIRHFASRAEEHMKGMMAPGTIFEELGFNYIGP
IDGHDVDTLVDTLSNMRSLGGPQLLHIVTQKGKGYRPAERDPIGYHGVPK
FDPKESSLPEKAPGIPSYSEIFGQWLCDTASNDKSLMAITPAMREGSGMV
TFSQQYPQQYFDVAIAEQHSVTYAAGLAISGLKPVVAIYSTFLQRGYDQL
IHDVALQNLDVLFAIDRAGIVGADGPTHQGAFDLSYLRCIPNMVVMAPSN
EQECLDMLTTGYQYKGPAAVRYPRGAGVGLELRKGKVIDIGKAQTLTEGQ
NIAFLNFGTLLPEVEAAAAKFNATVVDMRFIKPLDTACLDQLMTTHSVLV
TVEENVIAGGAGGAVSEYVAQHKASPQVLTIGLPDEFIKHGSQGEVRAEL
GLDAAGIERQVNDFIKKS
>IL0478 folA, Dihydrofolate reductase
MKISLVVAMADNRVIGKDNKMPWHLPDELQYFKKITLGKPIVMGRRTFES
IGRPLPGRKNIVLSRRTDRSENQDSQVVWVSGVQQAIAAAGPVEELMIIG
GGKIYEKFLPLADRLYVTKIELNVEGDTYFPDYHQVADWQEIERQNFAAD
ERNSHNFSTLIFDRVS
>IL1968 folB, Dihydroneopterin aldolase
MEQADIDVVSIEGLTVETIIGVYDWEKEKKQQLVLDIQMSWDNQRAAVTD
NIDDALDYALVSERVSAWVAEKPRQLIETVAEGVASLILNEFGVQNVEVR
VAKPGAVPNAKTVAVSVRRSVFDSPFG
>IL1015 folC, Folylpolyglutamate synthase
MAEISSSAPAVTASLQEWLTYLEKLHPKNIDMGLERVARVAANAGVLKPA
ALVITVSGTNGKGSTVCYLETILQAAGYTTGVYTSPHITEYRERVRVNAQ
ELPDSEHVKAFHAIEQARNNTSLTYFEFGTLAALWLMGRQSPDVAILEVG
LGGRLDAVNCVDADVAVVTSIGIDHIAFLGNNREHIGYEKAGIARSGKPL
ICGEASPTASIAESAERIGAKLYQVGRDFHRTEYDESWSYRSQNTQLNDL
PLPKLPLINASTAIAAIEQLPLPVSLSAIREGITQASLPGRMQPDTVNGI
EVLLDVAHNPQAAVYASRYLNKFYPQHKIFAVVGMLSDKDHAGVANALSS
QASAWYLGSLSEPRGETADNLVINAKLPTESCYLFESVEQAFAAAVTAAQ
QWQMNDGKALVFGFGSFYTVARINAYLKGA
>IL1008 folD, 5,10-methylene-tetrahydrofolate dehydrogenase
MPAQIIDGKTIAATVRQAVKQQVKERIDSGLRAPGLAVVLVGSDAASEVY
VGNKRRACEDVGFRSFDYDLPITTTQKELEKLIEELNDDDAVDGILVQLP
LPAGLDATPILERIRPDKDVDGFHPFNIGRLSQRIPALRPCTPKGIMTLL
EHTHVDLHGLNAVVVGASNIVGRPMSLELLLAGATTTVCHRFTKDLSDHV
KRADIVVVAVGKAEFIPGEWIKPGAIVIDVGMNRLPDGRLTGDVEFSVAA
ERAGWITPVPGGVGPMTVASLIENTLQACVDYHDVR
>IL1530 folK_1, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokin ase
MQKYLCSLGSNLEPETHFPQAQVALKALSDDIRFSRNIPTSPVDMDTNND
FLNALFIIRTPMSANELKQKFNAIEEAMGRDRSDPQRSFKDRTIDIDILG
RLEEKPPVPEYLTSLLPDLGLTS
>IL1967 folK_2, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokin ase
MAQVFLGIGSNTDREKHIRAGLKAIAKSFTWQQRSRIFRSASVGFSGSDF
YNLVVEVITNLSVTEVLAECKRIEQENGRIPGSAKFSPRTLDIDVLLYDD
VIREQQPQLPRGEILENAFVLWPLAEIAGHHLHPLLNVSYEQLWEQYQQT
HKDSPQQLEPISDTSWLEG
>IL2253 folK_3, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokin ase
MTQHKAFIALGSNLGKPMDNILSALKALNNDSRWQLLAYSSLYGSKPMGP
QDQPDYVNAVCSVSTSLPAAELLQALHDIEDAFGRKRVRHWGERTLDLDL
LLFDEQQHQSDSLRVPHPGLYERSFVLYPLVEIAADKLLPNGNTAKQQTE
TLTEEGLDVLICRSDITI
>IL0974 folP, Dihydropteroate synthase
MPKNPKPLRVMGIVNVTPDSFSDGGEYNHLNDAIDHVAQLIKDGADIVDI
GGESTRPGAYSVAEQEELDRVVPLVKAVRDRFDVAISVDTTKPQVMTESI
EVGANIINDVNALREKGALEALAATNAEVCLMHMQGEPRSMQHNPNYDDV
VCDVKTFLQERVIACEKAGIERERIWLDPGFGFGKSQRHNYQLLQRLQAF
HELQLPLLVGMSRKSMIGHVTGREVKDRLAGSLAAATIAAMKGARIIRVH
DVKETVDAMKVVAATIEGEHL
>IL1731 gshA, Gamma-glutamylcysteine synthetase
MQATFQAVIEKLKQSGKTAVWQGIKRGIEREALRIKENGTLAPGDHPQEL
GKTLTHPTITTDYSENLLEFITPVASDIDTTLSQLRDIHRVAYNAINDEL
LWPMSMPCYIGSDDDIRIAKYGDSHSGRMKSLYRRGLTYRYGATMQVIAG
VHYNFSVSDAMWEELAEIEGVSNNQSFRTERYFALIRNFKRVAWVIPYLF
GASPALCKSFFSQTKNEEILQKWDFDTVGKGTVFLPYGTSLRMSDLGYTN
KEQATLKITYNSLDEYVTGLRRAITTPSTQFSKIGVKVGDDYRQLNDNIL
QIENEFYSPIRPKQTARDGETPSQALERGGVEYVEIRALDVNPFSDVGIT
AQQMHFLDLMLLHCLLQPSEEMSWEQQQQADKNFTKVVMQGRDPRLSLQQ
NGIDRLMADWLEELFADFSSIAKALDNSSGNKVYQNHLADLYEWVLNPES
TLSGQILRLLKEEDRDNSNLGMQLAKQYREQLKNEPLSYYKQDDFVKWAA
ESEQAFEERYQQDNNVDFDTFLANYFKQAERSGQVAD
>IL2217 gshB, Glutathione synthase
MKKLAMVMDPIATVKTEKDTSFRLLLEAQARGYQCFYLEMGDLVIDNGQP
MAFAREVRVQDQKTDFYSLSDNEYRPLEDFDVIMMRKDPPFDSEFLYATQ
ILELAEQRGSLVVNKPQSLRDCNEKLFTSWFADSIADTLVSSRADVIKAF
HKKHGEVILKPLDGMGGASIFKVGADGSNLGVIIETLTEKGQRYAMVQKY
LPEIKDGDKRILIIDGEPVPYSLARIPSAGETRGNLAAGGSGRAQPLSDS
DWALARKVAPELKKRGLIIVGLDVIGDRITEINVTSPTCMREIENAYDIN
IAELVFKAIEEKLN
>IL0926 hemA, Glutamyl-tRNA reductase
MTISALGINHKTASVDLREQVAFSAEQLDAALQAVRNLQGVEEAVIVSTC
NRTELYCRGEVSGDLLLGWLTGFHKLAPNALENHHYHFQGEQAITHLMSV
ASGLDSLVLGEPQILGQVKQAYQAAKRQASVGGILERLFQQTFRVAKTVR
NETAVGQNAVSVAYAAVSMARHIFANLQKSKVLLIGAGDTSELVAQHLKQ
QGVTEILVANRTLQRASEMAERVGATAHSLSELSELLPQADIVVSSTAST
LPIVGKGSIEKALKKRRHRPMLLIDLAVPRDIEEQVNELDDAYLYTVDDL
QSIISENIRNREQAAREAQVIIQQQTKEFNDWLKSLNSVELVREYRTHTK
TLADEQLKKALAQIEQGKDPAEVLQRFSHRLVQQLTHKPTSLLKSAGENN
DQYTLAVLQQLWSEPSSDSSKGK
>IL2365 hemB, Delta-aminolevulinic acid dehydratase
MTNQGAFPGRRLRRLRRHDFSRRLVAENQLSVDDLIYPMFVLEGENQREQ
VSSMPGVDRVSIDLLLQECARLVELGIPMVALFPVTPASAKSEMAEAAYD
DNGLAQRAVKAIKADFPELGVMTDVALDPFTIHGQDGILDNSGYVVNDIT
TEVLVKQAVSHARAGVDVVAPSDMMDGRIGAIRSALEAEGFINTQIMAYS
AKYASAFYGPFRDAVGSAGNLKGADKKTYQMDPANSDEALQEIALDIQEG
ADMVMVKPGMPYLDIVRRAKDTFGVPTFAYQVSGEYAMLQAAIKNGWLGQ
DVIEESLLGFKRAGADGILTYFAKSVAERLATKKG
>IL2558 hemC, Porphobilinogen deaminase
MTQRVRIATRKSKLALWQAEHIQQRLEELHPGLSVELVPMSTKGDVILDT
PLAKIGGKGLFVKELEVAMLEGRADIAVHSMKDLPVEFPPGLELHTICER
EDPRDAFVSNNYKNLNELPEGAVVGTCSLRRRCQVKEQFPHLVIKDLRGN
VQTRLRKLDEGEFDAIILAASGLIRLELGDRITSFIPVEQSLPANGQGAL
GIECRSDDDEMKALLAPLQCQETRTRVLAERAMNRGLDGGCQVPIGAYAE
LEGDEVYLRGLVGEPDGGKVLRDEVRGPASKAEELGSELAERLLKQGAAE
ILSAVYDSESSHS
>IL2559 hemD, Uroporphyrinogen-III synthase
MNPVTHKAVLLLRPGKSPDDFTQQLRKTGRECFVHSFIEIEPLPVNKEQL
TQIKQKHWDGIVIVSKNAAHYASRAGFSGVPSKYYAVGPGTASFACKHLN
TAVSCPAFIHQSEGLLELSELQKLQQQNWLIIRGEGGRELLADAIRARGA
SVDYWEVYRRKQLTLNDPELIQQWISSVGTIVVTSAEQLGYFLSSMPNSA
QSWLDSCQWIVPSHRLKGLIPFGQSDNIKVTGSAADAILMNALIADGKTH
D
>IL2306 hemE, Uroporphyrinogen-III decarboxylase
MTAPALKNDRYLRALAKQPVDRTPVWMMRQAGRYLPEYKEVRGQAGDFMS
LCRNTELACEVTMQPLRRFDLDAAILFSDILTIPDAMGLGLYFEAGEGPK
FKDPVRSMAAIKNLAVPDMEDELGYVMDAVRAIRRELNGSVPLIGFSGSP
WTLATYMVEGGSTKNFSKVKQLMFADPEAMHTLLNVLAESVTQYLNAQIA
AGAQSVMIFDTWGGVLSPRDYKAFSLAYMEKIVAGLTREADGRKVPVTLF
TKNGGQWLEAMAASGADALGVDWTTDLSDARARVGGQVALQGNMDPSVLY
AKPARIEEEVQSILQSYGSGTGHVFNLGHGIHPEVDPEHAAAFIEAIHKY
SPAFHSND
>IL0023 hemF, Coproporphyrinogen III oxidase
MHNDYLKQVKSYLMSLQDAICQQLAQADGEQSFQEDSWDRPGGGGGRSRI
MKNGAVFEQGGVGFSHVYGEKMPASATAHRPELEGRDFNACGVSLVMHPE
NPMVPTVHMNVRFFIAQKEGEEPVWWFGGGFDLTPFYPFDQDIIEWHQQA
KNALDSVDEKLYPEYKAWCDDYFFLKHRDEARGVGGIFFDDLNDRSFDEC
FSVIKAVGDAFTKAYLPIVERRKNLAYTQQQRDFQLYRRGRYVEFNLVWD
RGTLFGLQTGGRTESILMSMPPLARWEYNWQAEPGSAEEQLTEYYLKPRD
WLSV
>IL2347 hemH, Protoheme ferro-lyase
MKYQGSPGFSHGQADKIGVLVTNLGTPEAPTKKALKPYLKEFLSDPRVVE
VPRLLWFLILNGVILRFRPKRSAEAYKTVWTDRGSPLLFHTQDQASAIEA
KLKQTWGDNIVVDFAMRYGNPALSEVVEKMMQKGVRKLLVLPLYPQYSAS
TTASTFDALAKDFTKRRWLPELRFITHYHDFSPFIEAAAQRIEKHWDAHG
RADKLLFSYHGIPLRYLKNGDPYHCECYKTSRLLAERLGLGKDEYLTTFQ
SRFGREEWLQPYTDMTMKALPGKGVKSVQVFCPGFSSDCLETVEEIGEEN
REYFMESGGERYEYISALNAESGHIDALSQLIENNLQGWSVEDVTEQRQQ
RADQVKKQSLPYDD
>IL2245 hemL, Glutamate-1-semialdehyde aminotransferase
MSRSEELYTKAQISIPGGVNSPVRAFNGVGGSPIFFESAEGAYMIDADGK
RYIDYVGSWGPMILGHNHPAVLEATLQAAKRGLSFGTPTEVEITMAETIR
KIVPSIEKVRMVNSGTEATMTAIRLARGYTGRDKILKFEGNYHGHADSLL
VKAGSGALTLGVPNSPGIPEDFAKHTLTATYNDIESVKQIFAEMGDEIAC
IIVEPVAGNMNCIPPVDGFLEGLRSICDDHGSVLIFDEVMTGFRVAPGGA
QDRYKIKPDLTTLGKVIGGGMPVGAFGGKKEVMDYIAPVGPVYQAGTLSG
NPVAMAAGLAALQQLSTPGLYDQLYQRVDTLLDGLQERADRAGVPMTTNR
AGSMFGFFFTEEPEVTTYAQATQCNMEHFKTFYHAMLEQGVYLAPSAFEG
GFMSAAHSEEDIQNTLNAAEKAFAKLV
>IL0190 hemN, Coproporphyrinogen III oxidase
MSTVTWDKELIEKYNINGPRYTSYPTALMLSEQFSESRIETALKNANDGL
CLYLHLPFCHKLCYYCGCNKVITRHQHKADKYLDYLAGEMAMYQPMVRDK
KIRQIHLGGGTPTFLTEQQLTRLMELVHQHFTFAENPEVSIEIDPRSCSD
EKLRHLRKLGFNRVSYGVQDFDKKVQIAINRVQDIELIAHQLKLSKELGF
ESINLDLIYGLPYQRPETFKKSIEQVIEMDPDRISVFSYAHLPQRFAGQK
KIPEESIPQPSVKLSLLEQAITQLNDAGYQFIGMDHFAKKDDGLAIAQRE
GRLQRNFQGYTTDGQDALLGLGVSSISQVNGVLWQHEKELPAYYKMIDNG
QKPIIKSMALNDEDKLRAALISQVICHFELDIEAFKAEWDLDDFWAHFAE
AIPLLKPFIEDGLVDVSDKKLRVTDLGRLWVRSICACFDEYLDHGQNRYS
KVV
>IL2560 hemX, Regulator of HemA biosynthesis
MTEENKIENEEVQNNEQSSEKSTEEETITAEKSSGRFFKRLVWLIVLIAI
VAAAYWGYTRFPGLFKTDSEQVSEQPQEDPIETRFKQLERSVGNLEQQLQ
NTVQARELDKLSNTDQQLERELTSLRQSLEDLRDDMRKTPAEKAAYWRLL
EIKQTLSAAARMMWSQDDYKAALQLLKLADQQLAGIDSRNAIRTREKLAG
DIERVNAAVKADNTDLAMQLVGLQQRVSDLPDEVNSNQQRLSSDTQNVSG
DVNDWQTNLSANWQSFLDNFIRIQPVDSDPKPLLSATQRTAINERIQLLF
TLAQQAAVKNNDELWQSYLDQLSKLIAQVKGDGAASQDIISRIQSLGQED
FEQQSIEQLESLDFIAQAIEQGDAS
>IL2561 hemY, Uncharacterized enzyme of heme biosynthesis
MKWIIALVVIIILGAIIGPLASGNAGYVLVQFAGVAIETTVVGLFVVTIV
AIAVLSVVVSLLRRLLSKTRQGRKWLANRSERKAQNIFQQGIRELLDDNP
EKATESLSKAYKKSPDNNIAALTAIAACLNKDAGKATYWHDEAGAFYDNA
DTLLQLVSIEQSVKKDPTEADKEMRSLLEAKPHSANVLKLAYRVFKASGN
WQQLKELLPELRRVTDLAPAEFDRLEYQVYFERFVAEGRKSNEMLYNEWR
SLPSKQRSDATIRLSYAAALKHLGDYEVSARVVLKGLKRGELQPAAVNSL
HLFNAKSEKLLEFVQAQLKQDPENRDYLYALAQIAMDNQDFSLAQRALKK
LAEIEPSSHVYRLLGNAYHALGDSQLAANAYKEALAH
>IL2585 ilvB, Acetolactate synthase, catabolic, putative
MKASDLFVKALENEGVKYIFGIPGEENLDLLESLSKSSIELILTRHEQGA
GFMAATYGRLTGKPGVCLSTLGPGATNLVTPVAYAQLGAMPMVVITGQKP
IKERHQGQFQIIDVVDMMTPITKYTQAIISASSIPAHIREAFRRAEDERP
GASHLELSDDISREEVSSLPIEASHSRRPITEHKSVRHVLELLREAKHPV
LLIGAAANRKITAKMLRAFVDKTGIPFITTQMGKGVINEDHPRWLGNAAV
SDGDYPHRAIEKSDLILNVGHDVVEKPPFMMKTGDNDNRKVVHINFQGAQ
VDSVYFPHASMIGDIGNSIWQLKEGIEPQSHWDFNFMLKVRDHMRDHTDE
GAHDGSFPVLPQRLVEDVREAMPDDGVIALDNGIYKIWFARNYPARQPNT
VLLDNALASMGAGLPSAMAAKLVNPEKKVMAICGDGGFMMNSQELETAVR
MGLDIVVVILNDSGYGMIKWKQQHMKLSDYGLDFNNPDFVKYAESYGANG
YRLDKTENLIPLLKDCLNKPGVHLIDVPVNYSQNDRLLNEEIPERSRAIK
DI
>IL1556 ilvE, Branched-chain amino-acid aminotransferase
MAAFGTVFMPQMTMATFENSDWSKPELVSSDAIQLHPGAHVLHYASTCFE
GLKAFRHEDGSINLFRMNRNIERMQQSSRLLSLPAFDAGLLQKMITDVVK
HFSDEVPKPPGSMYIRPTHIGTEAAIGKAASPTSSSMLYVLLSPVGDYFS
GGDKTLRLLLEEDGSRCAAHMGMVKSGGNYASALQPILQARESVNADQVL
FCPNGDVQETGAANFLLIDGNEIITKALDSSFLHGVTRDSILTIARDMGM
TVSERQLSVDELLERASKPDCEAALSGTAAVLAPVGTLIHNGKEFSVGSG
KSGATTLKLRKALNDIQWGKAEDKHSWLTKI
>IL0474 ispA_1, Geranylgeranyl pyrophosphate synthase
MMDMQSINALAKDDMLGVNALIGEQLQSDVALINQLGLYIVNSGGKRLRP
LLAILACRALGYEGNDHRKLATIIEFIHTATLLHDDVVDESELRRGRKTA
NAVFGNEASVLVGDFLYTRAFQLMVDLDSLRILRILADATNIISEGEVLQ
LMNCNDPDTSEASYFNVIYGKTAKLFEAATELAGVLTAQDEKVTQQLADY
GRYLGTAFQLVDDLMDYTADSESMGKNAGDDLAEGKPTLPLLYAMWHGNE
IEQKLIREAIEQGDGREHLQTVLTAMERTGALQYTRDKALEAAEQARESL
SELPDSDYKQALLTLTHLAVDRVA
>IL2137 ispA_2, Geranylgeranyl pyrophosphate synthase
MTINSLTAATREQVDSFLKQALAQLTLNPRLNQAMQHGVLMGGKRIRPYL
LVTVADICGANKNDALQAAAAVELIHAYSLIHDDLPAMDDDDLRRGQPTC
HIAYDEATAILAGDALQTLAFEVLTENRMEQLPSERQLQLVQVLAKASGA
RGMCAGQAIDLQATAKIVTEDALEQMHLSKTGALITAAATMGVLCGNDNA
QQWREKFEQFAHYLGLAFQVQDDILDVTGNTEALGKPQGSDTASEKSTYV
RLLGIEGAQQRLQNLHHKALQSLSDIPYNTDRLEQFSDLLLKRDH
>IL0270 kbl, 2-amino-3-ketobutyrate CoA ligase
MSSAFYQQLADQLAETKAEGLYKKERIISSDQSSEITVNNRKVLNFCANN
YLGLANHPDLIKAAKQGLDEHGFGTASVRFICGTQDIHKTLEQKLSEFLG
TEDTILYSSCFDANGGLFETLMGPEDAIISDELNHASIIDGIRLSKAKRF
RYKNNNLEDLEAQLKQADADGARHKLIATDGVFSMDGVIANLKGICDLAD
KYDALVMMDDCHATGFLGENGKGTHEYCDVIGRVDIITGTLGKALGGASG
GYTSGKKEVIDWLRQRSRPYLFSNSVAPAIVQASIRVLDMLAEGGKLRSQ
LWENASYFREQMTNAGFTLSGADHAIIPVMVGDAKLASEMSDRLLEEDIY
VIGFSFPVVPKGKARIRTQMSAAHTREQLDRTIEAFTRIGKELGVI
>IL0960 lipA, Lipoate synthase
MRDADKMALIPVQIIPTERDQMLRKPSWLKVKLPSSTERIDEIKQAMRSH
GLHSVCEEASCPNLPECFNHGTASFMILGDICTRRCPFCDVAHGRPLPPD
PEEAEKLGKTIRDMKVKYVVITSVDRDDLRDGGAQHFADCIREIREHSEN
NIQVEVLVPDFRGRMQVAIDILKGEAPDVFNHNLETVPRLYKAARPGANY
QWSLDLLQKYKEVRPDIRTKSGLMVGLGETKEEILEVMKDLRAHDVDMLT
IGQYLQPSRHHIPVARYVHPDEFEELRVAGVEMGFSHIASGPLVRSSYHA
DLQAAGETVR
>IL0959 lipB, Lipoate-protein ligase B
MNDTLIIRELGRQPYEPVWHAMQEFTDQRDEHTADELWVVEHDPVFTQGQ
AGKAEHILAPGDIPVIQVDRGGQVTYHGPGQLVIYFLLNIRRLNYGVRQL
VNHIENTVIETLSDYEIDAKARRDAPGVYVDTDKICSLGLRIRKGCSFHG
LALNVNMDMEPFSRINPCGLSGIKMIQTKDLNGPDSFSEAADAVIKHFTS
SLSYSNILQQTGLAQDYVKAS
>IL0300 lplA, Lipoate-protein ligase A
MHGEYKVPGGKLVVADVNLEEGCLSEVSISGDFFLEPDSALNLINEALTG
LPETSSHKTLAAAIDEALDEDVMMFGFSAEAVATAVRRALGKASSWLDHQ
FTLIPPVTLPAAEHAALDEVIADSVAKGLRGPTLRFWDWDDSVVVIGSFQ
SVKNEVDMAAAKEANVQVVRRATGGGAMFMEPGNCITYSLTVPTSLVDGM
SIEKSYEFLDAWVLAALAEVGIKAYYKPLNDIASAQGKIGGAAQKRFANG
VVVHHATLAYDIDANKMLQVLRTGREKLSDKGITSANKRVDPMRSQTGLT
RTAIIDAFMNQFTQAYQTQVDDYLPQELSAARALVETKYLTEEWLYKVT
>IL2455 menG, Demethylmenaquinone methyltransferase
MEYNTSELCDLYPDMVDVVEPMFESYGGRSSFGGSLVIIKCHEDKGLIEE
TIAADGGGKILLIDGGGSSRRALVDAAIAEQAMDNDWEGIVCYGAVREVD
ALEELDIGILGVASIPVGAISEGVGELNVPVNFGGVTFLPEDHLYIDTTG
VILSPEPLDIE
>IL2215 metK, S-adenosylmethionine synthetase
MSRHLFTSESVSEGHPDKIADQISDAVLDAILAKDPKARVACETYVKTGM
VLVGGEISTKAWVDVEDLARQTVKDIGYRHSDMGFDGASCAVLNAIGKQS
GDINQGVDRANPEEQGAGDQGLMFGYASNETSVLMPAPITYAHRVMQRQS
EVRNNGTLDWLRPDAKSQLTFVYENGKPVAIDTVVLSTQHREDITQETLR
EAVMEEIIKPVLPEQWVSKDTQFHINPTGRFVVGGPMGDCGLTGRKIIVD
TYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNLVAAGLAERCELQIS
YAIGVAEPTSISIDTFGTSKHSEEQLIALVRRHFDLRPYGLIKMLDLERP
IYKQTAAYGHFGRDNLPWEQTDKAADLQADI
>IL1077 nadA, Quinolinate synthase
MDSLDYTFPPKPKPLSAEEKSETINRIKQLLIDEDAVLVAHYYTDPDIQA
LAEATGGCVADSLEMARFGRDHPAKKLIVAGVRFMGETAKILTPHKEVLM
PTLKAECSLDLGCPPEKFAEFCDQHPDRTVVVYANTSAAVKARADWVVTS
SMALELVDHLDAKGEKILWAPDKHLGGYIARETGADMLLWQGACVVHDEF
KAKALQDMKKLHPEAAILVHPESPENIVAMADAVGSTSQLIKASQELPNE
TFIVATDKGIFYKMQQLQPNKTFIEAPTAGNGATCRSCAHCPWMAMNGLK
AIEEALTDGGETHEIHVDEALGKKAMVPLDRMLEFAATLK
>IL0817 nadB, Aspartate oxidase
MEPVANYQCDVLIIGSGAAGLTTALQLADNLNVTVLSKGPLTEGSTFYAQ
GGIAAVFDENDSIESHIEDTLIAGAGLCDPEAVKFTTENARASLQWLIDA
GVGFDQVESKDSNPAYHLNREGGHSHRRILHAADATGKAVQTTLQKKAME
HPNIQVLERYNAVDLITGSRIGKPDGCYGAYVWSRQKEQVETVAAGCVVL
ATGGASKVYQYTSNPDIASGDGIAMAWRAGCSVANMEFNQFHPTCLFHPN
AQSFLLSEALRGEGALLKRPDGTRFMPDFHESAELAPRDVVARAIDFEMK
RLGADCMYLDISHKPKDFIQHHFPTIMEKCLSLGIDISKQPMPVVPAAHY
TCGGVKTDMNAATDLPNLYAVGEVACTGLHGANRMASNSLLECLVFARAA
AKDILSKRPHQKALNHIPGWDESQVGNSDEEVIIQHNWHELRLFMWDYVG
IVRTTKRLERALHRIQLLQREIHEYYSNFRVSNNLLELRNLVQVSELIVR
SAISRKESRGLHYTLDYPDTLPDPQPTVLTPKS
>IL0454 nadC, Nicotinate-nucleotide pyrophosphorylase
MSQPELQLAIQDGVRAALKEDLFGEDARLDITAQLIPEQSQSRASIITRE
DAVICGCAWVDQVFRQMGNQVEIEWLVKDGDNVKANTELCRLKGPSRILL
TGERTALNFLQTLSATATTTYHYSKLLDGYKTQLLDTRKTLPGMRLAQKY
AVRCGGGVNHRIGLFDAYLIKENHIFACGGITQAVATAKRLNPGKTVEVE
VENLDEFGQALKAEADVIMLDNFSIEDIKQAVQQNRDNAGHSAQLEVSGN
ITDERLPELAATGVDFISSGALTKNVQAIDLSMRISEDN
>IL2321 pabA, P-aminobenzoate synthetase, component II
MIVLIDNFDSFTHNLARYFRELGEDVSVFRNNELTLTDIEQLAPQALVIS
PGPCTPNESGISLAAIEHFQTKLPILGVCLGHQALAQVFGANVVRAEKVM
HGKTSVIKHSGEGLFRQLNNPLEVTRYHSLVVSPESLSTDFVIDADTGTE
KGQREIMAIRHRHLPLFGVQFHPESVMTAQGHNLLANFLRYIR
>IL1706 pabB, P-aminobenzoate synthetase, component I
MSVFPDLCAIKLDCEASAIELFQRCQHESYALLLDSAAQSHQNCAYDIIF
RQPELILNCKAGKLNVSTDAPLELPPAPEDAAELCRYAGQLNQLSGHYSG
PAELPFQGGFAGAVGYDHGRSLEVIPEFNADIYQSPDAVLAYYSQALIID
RQSNAIWLVAPIEGSEELREFWEQPVATKKPDAFQLLSDWQSNMSEQQYT
EKFKAVQNYLLAGDAYQINLAQRYSARYQGSEWSAYLKLRQANSAPFSAF
MRLPGSAILSLSPERFLLTDAKGLVETKPIKGTRPRFENSLKDQASQQAL
LTSEKDRAENLMIVDLLRNDLSKNCKPGSIKTPSLFAIESFPAVHHLVST
VIGKLQPDRTALSLFNGAFPGGSITGAPKIRAMQIIEELEPHRRSIYCGS
MGYFSQHGRSDTSITIRTLLAENDHLYCWAGGGLVADSTAADEYQETKDK
VSRILPVLTS
>IL1338 pabC, 4-amino-4-deoxychorismate lyase
MHIERHLNRLSEANTRLFINHPNFNFLHQRILNACDGIENGVCKVIVTRG
YGGRGYGFSDGAVANEYIQVSDAPGNLKSVSLGVAELNLARQPKLAGLKT
LNRLEQVLLTQERSVSEYDDLLVCDSEGNVVEAIQGNVFWYKQGQWYTPD
LSFSGVQGIIRQLIIDEDMLAPLRIGHFSLNELADVEQIILSNSVRGAVT
VTQFNGKVLDKSKLPAVLEQLIL
>IL2254 panB, Ketopantoate hydroxymethyltransferase
MATTKTSIATLQKMKREGTKISSLTAYDSSFAKLMTEQGVDFILVGDSLG
NVVQGRDSTVPVTVDDMIYHTQCVRRGASNAFVIADMPFMTYSTPEQAYD
VAAALMQAGANMVKLEGGHWLVETIEGLKTRGIPVCAHLGLLPQSVNVLG
GYKVQGKEQQQADDTLNQALALEQAGAQLLVLECVPASLGKRITEQLSIP
TIGIGAGADTDGQILVMHDMLGMNSDYLPKFAKDFLAQGGSLADAFRLYS
EQVRSGEFPTAEHSYK
>IL2255 panC, Panthothenate synthetase
MRILKSLAELRRWRQQQSEVALVPTMGNLHDGHLQLVKTALERCDNVVVS
IFVNPMQFGANEDLDSYPRTLEADCQALDALGVSAVFTPQVNDVYPRGLD
KQTRIEVPGISDILCGASRPGHFTGVATIVCKLFNMVQPQLAVFGEKDYQ
QLQVIRLMVQDLSLPVEVLGTATQRETSGLAMSSRNGYLSTEQKHQAAEL
YKTLEETKAKLSVNTDFGELEAAAKEKLTQAGFVPDYFSIRNAADLQEAT
PEDHEWVILAAAFMGKTRLIDNLRVTNAAAK
>IL2231 pdxA, Pyridoxal phosphate biosynthesis protein
MSIPTLVFTPGEPAGIGPDLIIKIAQQPWSAAVVVCADKNLLKQRAEQLN
LPITLHRYRKGEELPQHEPGHLWVEHIPVCEDVIPGELCTANGHYVVDCL
KRASDGNLSGEFDAIVTGPVHKGVINQAGVAFSGHTEFLAHEANCNDVVM
MLATEGLRVALVTTHIPLAYVAKAVTAERLTNIITILHNDLTKKFGESSP
KILVCGLNPHAGESGHLGREEIDIIIPVLEQLKKQGMNLHGPYPADTIFQ
PKYLEDASAVVAMYHDQGLPVLKYKGFGQAVNITLGLPYIRTSVDHGTAL
ELAGSGKISDGSCRLAMQTAIDMARAAYYE
>IL1020 pdxB, Erythronate-4-phosphate dehyrogenase
MKIVADQNIPALSDLLSGAGTLSYFSERIPPQKLLAEADALLVRSVTQVD
EVLLEQAPELKFVASATIGTEHINLQALEERGIGFAHAPGANAQSVGEYV
LCAVLNWLSDQPRYVADEIDVAIVGAGHTGKAAGKRLEALGLNVHYYDPP
LCKKGVKFVHDHWQRVLTADIISCHVPLTRDGDFPTQHLFENTALQSLHS
QQLLINASRGAVIDNNALLERVEQGERPSLVLDVWENEPEVLSGLVPYVD
IATPHIAGHSLEGKVGGAVMISNALLEHFGKPADKTLSDVLPGKAWNERD
AGGLNSLESLNLWAKEHYDLFRDDELFRQQGLTTEGFDSLRRNYRKESPR
REFINQVVTCHNSEQYIQFLQLGFSARLLSK
>IL1209 pdxH, Pyridoxamine phosphate oxidase
MDLQAMRREYGLGSLHREQLEADPVKQFEKWMQQAIDSNLLSDPTAMTLA
TVDAEHMPSQRIVLLKGYDHTGFRFYTNKNSHKGQDISENPQVALHFAWL
PLERQISIIGSAVPLDDDDNDRYFHSRPKESQVAALASQQSRPVESRDVL
ESHYQSLLKDYENTEVPRPQSWGGYCVHPKQFEFWQGGQHRLHDRYQYSK
DRENWRITRLQP
>IL0807 pdxJ, Pyridoxal phosphate biosynthesis protein
MKGLRLGVNIDHVATLRNARGVRYPDPVAAAAIAEQAGADGITIHLREDR
RHITDRDVAMLKQTLNVPMNLEMAVTEEMLDIAIKTQPTYSCLVPEKRQE
LTTEGGLNVAGQLETITDATRRLSDAGIQVSLFIDADHEQIDAAKKAGAP
IVELHTGQYAEAETEEQRTVELARLMEASEYAHSIGLQVNVGHGLHYHNT
LEVAEIPQVCELNIGHSIIARAVLVGLDQAVRDMRNILDKAR
>IL0103 pncB, Nicotinic acid phosphoribosyltransferase
MTGTERQDLGLFTDLYQLTMLDAYLQEGMQDDAVFTLFVRRLPNERKFLL
AAGLDPLLETIENLSFSDDDLRYLKEQNFSQQLIDYLRDFEFTGQVRALP
EGTVFFENEPIVEIKAPLPQAQLIETLVMNQIHLQTLLASKGARVAHAAE
KRPVLDFGARRVHGIDAGKKGSRALYLSGIAATSNMLAARTYGLPVAGTM
AHSYIQAHDSEYQALKNFTQVFPETVLLVDTIDTLKGVEKVIQLANELGD
DFKVKGIRLDSGDLGDLAVKARKLLDEHNLHHLEIIASGGLDEHKIAQLI
ADRAPIDGFGVGTGMGVSDDAAALDMAYKLVEYAGKGRLKLSSGKPVLPG
EKQVFRESGDNFRRDTIARAEEQLPGEPLLKKVMQSGKRLPSHQRDIEEI
RQYAQQQLNKLPEYVSSISSKEKSYPIEISDKLASYQKEITEHLKQEG
>IL2356 pnuC, Nicotinamide mononucleotide transporter
MPESLLESWLEQLMVSSPWELTALVMALGYLVLAAHQRQWCWAAAAVSCT
IYAVLFWQGKLYMESLLQTIYIALAGYGWWQWQRQQSAAKESPDGAKYPF
RWHLLQWAWLVPLAAGIAYLLSVYTDADAVWLDTYTTIFSLLATWLVTKK
AYETWWYWLVIDSVYVYLYASKGFVATALLFVVYLILVIYAMWRWRHDIS
LKSASEAG
>IL1869 ribAB, 3,4-dihydroxy-2-butanone 4-phosphate synthase
MSLHSTEEIIEDIRQGKMVILMDDEDRENEGDIIIAAECVTPETINFMAR
YGRGLICLTLTEERCEQLNLPLMVDKNNAPYATSFTVSIEAAEGVTTGIS
AADRAKTVLDAVKKDAKPEDLVMPGHIFPLKAKSGGVLNRAGHTEAGCDL
ARLAGFEPAAVIVEVLNEDGTMARRADLEAFSEEHGIKVGTIADLIEYRS
IQEKTIERVAECNLPTAFGKFRLITYQDTIDEQVHYALVHGDLSQDKVTN
VRVHLQDTFHDTFLTERAAKRSWPIQKAMSYIAEHDGVLVIIGRQQTPES
IIAQVCEFEAQDKGEQKPTTSASNASRNVGLGSQILADLNIHKMHLMSSP
KRYSALSGFGLEVVDFIEDKD
>IL1402 ribC, Riboflavin synthase alpha chain
MFTGIVQTQATIFSVSDQGSFRHLVVKTEPQFLQNLAIGASIAINGCCLT
VVEFSDTEVHFDVIDETLRLTNLGLLGEGDKVNLERSLKVGDEIGGHAVS
GHIHCQGKVNKIDTSENNVAMWIELPEQYTPYLFAKGFIAVNGASLTVGQ
VEANCFSLHLIPETLRLTNLESTQVGDSLNIELDQQTITIVETVERVLAK
RQ
>IL1870 ribD, Riboflavin-specific deaminase/reductase
MTELNPQYFDHQMMHRALMLARRGLMTTRPNPAVGCVITLGTEVVGEGWH
HQAGEPHAEVHALRAAGQKVRGATAYVTLEPCSHIGRTPPCCDALIEAGV
KRVVVAMQDPNPRVSGNGIQRLKAAGISVDVGVLQLAAESLNPGFISRMT
RQRPWVTLKMATSLDAKTALSDGRSQWITSSDSRSDVQFFRAQADAILSG
AATILADDPKLTVRVDQWPKSRPLPEPLKQPVRIIIDSQHRVNDEARVFD
SPAPVWLVRTTPGKPSCHPHCHELIIAADPNGKVSLPALMVELANREINQ
LWTECGANLAGALIQQQLCDRLMIYSSGQLLGHHGRSVIDMNEPLNLASA
PRFKIIDRRQVGPDQRLVAVPHTQD
>IL1129 ribF, FAD synthase
MELIRGTHNLRAEHCGCVLTIGNFDGVHLGHQAVLSQVREKAQQLGMPSA
VMTFEPQPQELFQPEKAPARLTNWREKYLALQAQNVDRHIVVEFNKKFAS
QPAREFIEQTLVGKLGVKFLVVGDDFRFGYKREGDFELLQKAGKELGFEV
VDTRSYRQQQQRVSSTAIRQALEEGDFEQAEQMLGRPYQICGKVVHGRKN
GRTIGFPTANVPLKRLKSPLHGVFAVTAQFGKDEEIHSGVANLGTRPTLN
GDEVQLEVHLFEFSGNLYGQQMTVTPVAKLRNEQRFASLQHLQEQIEKDA
ARAREALACRSQ
>IL2142 ribH, Riboflavin synthase beta chain
MQVIEGGINAAGKKFAIIVSRFNHFMVESLLDGAVQTLKHYGEVADDDIT
VVRVPGAYEMPVTAKRLASSGKYDAIIAVGAVIRGGTPHFEFVAGECNSG
LGRVATEFDLPVAFGVITTDTLEQAIERSGSKAGNKGSEAALSALEMVNV
LKQL
>IL0497 rimK, Ribosomal protein S6 modification enzyme
MRIAILSRNASLYSTRRLVEAAEERGHEVDVLNPLRCYMNINARESSIHK
HGKELPHYDCVIPRIGASVTFYGTAVLRQFEMIGSYPLNESVAISRSRDK
LRSLQLLSRKGIGLPTTGFASQPQDIPDLIDMVGGAPLVIKLLEGTQGIG
VVLAETRQAAESVIEAFMGLHSNFMVQEYIKEAGGADIRCLVIGDKVIAA
MKRQAKAGEFRSNLHRGGSASLVKLTPAERATAVKAAKTMGLNVAGVDIL
RSNHGPLVMEVNSSPGLEGIEQATEKDVASQIITFLEKNAKAHKTRTKGQ
G
>IL2104 serA, D-3-phosphoglycerate dehydrogenase
MQISLAKDKIKVLLLEGVHESAIQLFRHHGYHNLEILQTSLSEDELCEKI
KDAHILGIRSRSQLNDRVFAAAEKLIAVGCFCIGTNQVDLEAAKKHGVIV
FNAPFSNTRSVAELVLAEIIMLLRGIPEKNAVAHEGGWLKSAKQSYEARG
KILGIVGYGHIGSQLSVLAEQLGMHIRYFDIEDKLPMGNAQSVATLDDLL
AQSDIITLHVPENEQTQWMIGRRQIERMKPGSLLINASRGTVVDIDALAE
ALSSRHLAGAAIDVFPVEPKGNSDEFLSPLRGLKNCLLTPHIGGSTLEAQ
ENIGVEVAGKLVRYSDNGSTLSAVNFPEVSLPTHATAQRLLHIHKNQPGM
LNAINRIISDNEINVVGQYLQTDENVGYVVMDIDSDNGADVLQQLKDIPG
TIRARRLF
>IL1359 serC, Phosphoserine aminotransferase
MSQLFNFSAGPAMLPVDVLKQAQEELLNWNGQGVSVMEISHRDPVYVHMA
REAEQDLRDLLNVPDDYEVLFLQGGGRGQFSAVPQNIASPDATVDYLDTG
IWSGFAIREAEKFVSKVNVAGQVQEGAKGKEIQSPENWKLSENAAYFHYC
PNETVDGIALHEIPDVKAPIVADMSSNILSEPLDVSKFGVIYAGAQKNIG
PSGFAIAIVKKSLLGHPQKQVSSIMDYQLQAKDGSMYNTPNTFAWYLAGL
VFKWLKAQGGLTAMGERNRHKAQLLYDFVDKSDFYRNDINPAYRSIMNIP
FQLAYDKLDAEFLQGAKNQGLLGLKGHRFVGGMRASIYNAMPVEGVEALL
NYMADFERKLG
>IL0765 thiC, Thiamine biosynthesis protein ThiC
MSTAPSNNRLNRQQAESFLSSLSGHYYPNSSREFISGSNKDIQVPFRRIH
LSETLHQPTPGVKLPPNEPVDVYDTSSVYGDPDATIDVKAGLKKVRENWI
QERHSENQQYNHGITQLAYARRGVITPEMEFIALRENMGRGHLKNPITPE
FVRDEVASGRAIIPVNTHHPESEPMIIGRNFLVKVNANIGNSSVSSSIEE
EVEKLVWATRWGADTVMDLSTGRNIHQTREWILRNSPVPIGTVPIYQALE
RVNGVAEDLSWPVFKDVLLEQAEQGVDYFTIHAGVLHDFIKLTAKRVTGI
VSRGGSIMAKWCMAHQQESFLYQHFRDICKICAKYDVSLSLGDGLRPGSI
ADANDEAQFAELRVLGELTQIAWEYDVQVMIEGPGHVPMHKIQENMDEQL
KHCHGAPFYTLGPLTTDIAPGYDHITSCIGAAMIGAFGCAMLCYVTPKEH
LGLPNKEDVKQGMIAYKIAAHAADLAKGHPGAQARDDAMSKARFEFRWED
QFNLALDPVTARSYHDETLPQDSNKTAQFCSMCGPKFCSMKISHEVRQYN
PDTRIDVKVKDAATEGAE
>IL0766 thiE, Thiamine monophosphate synthase
MSIPVVWTIAGSDSGGGAGIQADLHTFRSLNVHGCSVISTITAQNSVATT
GLFPLAADAVRQQLECLQQDMPPAAIKIGLLSNVQQLQCVADFLKQWSDP
LPQPFVVWDPVVVSTQQDRLSELKPQHCAELFPLVDIMTPNLDELSWLSG
LEVTDEDSMYRAAEQLFQAGLSRILVTGTDFGRADEISDYYLSSDGHTQY
IQQKLRTKHSHGTGCTLSSAIAAALAHDYPLEDAITVANAYVHQGLIEAK
GIGRGPGPVAHTHWPQQIDHFPKINTPELPCVDLQFPSLDQEPGLYPVVD
SYEWIEKLLKLGIKTLQLRIKDPDAPQLETAIKKSIQLAEKYSAQLFIND
HWQLAIKHNAYGVHLGQEDLTEANLHAIQQAGLRLGISTHSYTELLIAQA
YKPSYIALGHIFPTQTKTMPSKPQGLQRLRRYAALLAPKNIPTVAIGGIS
LERVAPVTATGVNGIAVVSAITAARNVEQAVHQLLTEMEAELEVKEKNEV
AHAE
>IL0767 thiF, Thiamine biosynthesis protein ThiF
MLSNEQLLRYSSNILMKEIGETGQQRLLKSHVLIIGLGGLGCPASQYLAS
SGVGQITLVDHDTISLSNLQRQTLYSSDGIGLSKAWQAGHSLSRLNPDIR
ITAIEEKAYEGNLDALAEQADLVLDCTDNRETRYLINQSCYRLNTPLISA
AARGFNGQLIALNPGQSHGCYQCLYPDAVTEPLNCSNAGIAAPVVGIMGS
SQALLAINYFTGHKLAWGYLQTFNGLSQNWQQLYLPRAASCPVCGGQNAH
SN
>IL0769 thiG, Thiamine biosynthesis protein ThiG
MLRIADRDFHSRLFIGSGKYSSADIMQKSLAASGSELVTLALKRVELERP
TDDIVTPIQNLGLQLLPNTSGAKTAQDAIFAARLAREALGTHWLKLEIHP
DPNYLLPDPIETLKAAETLVKEGFTVLPYCGADPVLCKRLEEVGCAAVMP
LGAPIGSNQGLLTRDFLRIIIEQASLPVIVDAGIGAPSHAVEAMEMGADA
VLVNTAIATANDPVAMSKTFRDAVIVGRQAFEAGLSQNASLKASASSPLT
EFLESL
>IL0770 thiH, Thiamine biosynthesis enzyme ThiH
MSFYTTWEQTSWDDTRLQLYSKNAADVETALSKQHLNTGDFMALLSPAAE
SYLPLMAERSQQLTRQRFGNTLHLFIPLYLSNLCANDCSYCGFSMSNRLK
RKTLSPTEIEQECQAIKAKGFDTLLIVTGEHETKVGIDYFRHALPIIKRY
FSYVMFEVQPLATHEYAELRTLGLDAVMVYQETYQAATYAKHHLKGKKRD
FRWRLETPDRLGECGIDKIGLGSLIGLEDWRIDSTFTAMHLDYLRRRYWR
SRYSLSFPRLRPCAGGVDNARTISDKQLVQLICAYRLRFPDVELSLSTRE
QQALRDGLFRLGVTSVSAESKTQPGGYANEQQELEQFSIDDDRPVSEVAQ
AIKAKGLQPVWQDWLNELSAMPPETFSSPE
>IL2140 thiL, Thiamine monophosphate kinase
MPRDEFSLINEYFTHRSAKRGDVAMGIGDDGAVVRPMPEHDLVIVTDTLV
EGVHFDMTTPPRAIGHKSVAVNLSDLAAMGAQPCWISLALTLPRMDEDWL
QEFSGGLDEICSYYDCQLIGGDTTKGPLTITITAHGQLPSGSAIPRSGAK
AGDWIYVSGSLGDAGLGLQVTQNKVSTTGRHLQQVIERLHYPTPRVALGQ
SLRGVASSCIDISDGLLADLRHLMTEAGTQAQLELEKLPLSLALTETLQV
DDALALALTAGDDYELCFTLPEEHRGRMETLTTHLKTRPVCIGRVANGES
GDIQLRYNGEDWLLAEGYSSFNHFPQNEASK
>IL0768 thiS, Thiamine biosynthesis protein ThiS
MRIQINDKDFEITEKTNLSQLLSAQNVDTSAVAVALNGQIIHREQWQQTE
LKDNDTITLVQAVAGG
>IL1751 trpE, Anthranilate synthase component I
MKNLTTEQNGNLETLRVSLPYQAEPLKVFQNTCSTQGEHLLLDSADIGTK
QQVKSLLLIDAALRITCNDQQVTIIALTDNGAVLLSWIEEQLKDSAAIER
TPEQLRLTFSAANTPIDEDSRLRQISNMEPLRVLQQKLNKANNTAKQHPF
SVFLGGAFAYDFVASYEQLPQVDEGENNCPDYVFYLAETLLIIDHQQQTT
ELLGSVFSGKGHDQRYQAMSQRIGELAARCQLPAIEPQPQPVDVQVTATP
SAEEFARIVTRLKENIVAGDIFQVVPSRRFKMPCPDPLAAYQQLKKNNPS
PYMFFMSHPDFCLFGASPESALKYQQDINQVELYPIAGTRPRGKSADGSI
SPDLDSRMELELRLDQKELAEHLMLVDLARNDLARISETGTRYVADLLQV
DRYSHVMHLVSRVVAKLRNDCDALHAYRACMNMGTLVGAPKVSAATLIRQ
VEKQRRGSYGGAVGYLAGNGDMDTCIVIRSAFVKNNQAIVQAGAGVVHDS
DPTSEVTETENKAKAVILAIQQAHTLPDQEAV
>IL0264 ubiA, 4-hydroxybenzoate polyprenyltransferase
MQKLVAFWQLMRADRPIGTYLLAWPTIWALMIAGAGEPPLRIVVIFLLGT
FVMRSAGCVINDFADRNYDGHVRRTRQRPIPAGRISATEAMIGFIALLAI
AFGLVMQLNTETVMLSFFAAGVAALYPFCKRWTHLPQIVLGIAFSFGIPM
AFTALESDQWFIAGLLFLANILWTVAYDTEYAMADREDDLKIGLQSTAIL
FGRFDRLAIGLLQLATLALLGWILHLITVELWVWLALAAIFLLFAYQHWL
IRHREPGKCFQAFLHNHYIGMVFAIGLAVHYWF
>IL2359 ubiB, 2-polyprenylphenol hydroxylase
MSQQMTCKAEISRQLADAVWEVRLQLPQPVEFKAGQYLMVVMGERDKRPF
SIASCPSNKSEWLLHVGATPDNSYAMEVLDKVRDDGELEIDAPDGIAFYR
QENTKPAVLIAGGTGFSYTYSILQQHLRVSPERPLTLYWGAKSLSDLYLH
DELERLASQYEHFDYHPVVEDADNNWAYSIGLVHHAVMAREQSLPECEIY
MAGRFEMIRVIRDDFVAKDVPLENLYGDALSFI
>IL0265 ubiC, 4-hydroxybenzoate synthetase
MTTEFYATPAFPVSKALQWTPPEQLELTPTQADWLLYEGSLTERLKQIGQ
QFSVKLLGQQLLAPNTEEKQRLKGKDQAVIREVLLYCNEKPWVFARSLFS
PSAENANTLNLQQLGNQSLGESLFARSDLYCGDIEVAKVALEHPVARLNQ
QWFGINQRLLSRRRIFSTGGEQLLVSEVFLQPSPLYSSPNNRS
>IL2360 ubiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase
MKYQDLRDFIALLEERGELKRIQQEIDPYLEITEISDRTLKAQGPALLFE
NVKGHDMPVLANLFGTPDRVALGMGQESVTALRDVGKLLAFLKEPEPPKG
FRDALNLLPKYKKVLSMSPKSIKKAPCQQVVMSGDDVDLTKLPIQHCWPG
DVAPLVTWGLTVTRGPHKERQNLGIYRQQLLGPNKLIMRWLSHRGGALDF
QEWCQQHPGERFPVSVALGADPATILGAVTPVPDSLSEYAFAGLLRDSKT
EVTQCLSNDLQVPAHAEIILEGYIEPGEMAAEGPYGDHTGYYNEVDEFPV
FTVTHVTHRKDPIYHSTYTGRPPDEPAVLGVALNEVFIPLLQKQFPEIVD
FYLPPEGCSYRLAVVTMKKQYPGHAKRVMMGVWSFLRQFMYTKFVIVCDD
DVNARDWKDVIWAMTTRMDPARDTTLVENTPIDYLDFASPVSGLGSKMGM
DATNKWPGETDREWGEPIVMSDEVKQRVDELWDELNIMES
>IL2373 ubiE, 2-polyprenylmethoxybenozoquinol methylase
MNDKNEESIDFGYQKVARNQKKNLVADVFQSVAAKYDVMNDLMSFGIHRL
WKRYTIDCSGVRRGMKVLDIAGGTGDLTAQFSRRVGAEGEVVLADINDAM
LKVGRDKLRDRGIIGNVRYVQADAEELPFDDNTFDVITIAFGLRNVTDKD
KALRSMLRVLKPGGRVLILEFSKPVSATLNQVYDFYSFNILPKMGQVVAN
DSDSYQYLAESIRMHPDQETLKSMMEAAGYEKVDYQNMTGGVVALHRGYK
F
>IL1361 ubiG, Demethylubiquinone methylase
MTTSRSKSEQKNVDPEEIAKFSALASRWWDPDGEFKPLHKINPVRLGFIE
NHTDGLFGKKVLDVGCGGGLLSEAMAERGAQVTGVDLAEQSLKVARLHAL
ESGRQIDYQCIAIETLADQQPASFDVVTCLEMLEHVPDPKAIVKACAKAL
KPGGKIFFSTLNRNVKSWLLGIVAAEHVLGWVPKGTHQHQRFIKPSELLR
MTDAAALEDIAINGLIFNPLKGFVLSEKDVDVNYIIALKKPES
>IL2097 ubiH, 2-polyprenyl-6-methoxyphenol hydroxylase
MDEKPVTQADVVIAGGSLVGALTGLMLAQQRPDWRIVVCEPRAEGPPADK
RIIALAAASAKRLQSLGALDGIDSTPIKHIHISDRGFAGAAELHAEYEKV
EALGRVVSASELVNNLYLSCQQQPNLNWLSGVRLESLQQQQDYVELTLDN
AQKLQAKLLIGADGQNSLVREQLELKSDTYDYGQFGCIATLDMKQPLDGW
AFERFTEAGPIALLPMQNSQASLVWSFTEKQREAAEQWSDTEFLHRCQQA
FGYRAGLFSGVSKRVFYPLILRRAKRSTHHRSVIIGNASHALHPIAGQGF
NLGLRDTEVLCEVLATTDDPGNFRVLQGYEQNRERDYQAIIKLTDGLVRG
FSNHYLPTVVGRNSALMLLQHCSPLKSAFARLTMGMKP
>IL2260 ubiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase
MKTDNRITVAITGASGAPYALRLLQCLLDQDQQVMLLISSAARVVLATEQ
GMQIPAAPDKAAAMLCEHFSVGAEQLKVYGKEEWFSPVASGSAAPAKMVV
CPCSTSTLSSIAHGSSNTLIERAADVVLKERGQLILVPRESPLSTIHLQN
MLQLSQQGVTIMPAAPGFYHQPESIDDLIDFMVARMLDHLGLEQRLVSRW
GYGKES
>IL2096 visC, FAD-binding oxidoreductase, UbiH/Coq6 family
MTMKRKKLDVVIVGGGMIGLSLAIRLAQQNRRVMVLERHSQPELSEELAL
RVSALNDRSRSVLKDCGAWPLVQEHRSGPYQSMQVWDKDSPAHIEFSAKE
INAEDLGAIVENNVVEHFLWQRAEQAGVEILQTQQWTMVHGGDESHPAEI
EVGEWLLSADLIIGADGGRSKVRQYAELPISFWDYGQQGIVANIRTEQPH
NGVARQVFLPTGPLALLPTPDSHTVSIVWSADEALARNLLNEPAERFAKQ
VETESGRVLGGCECVSDIKAFPLRMQYARQWYQHRIVLAGDAAHTIHPLA
GQGANLGFGDVKALTEKLEGVDLSSLAQLHRSLSTYQRERKADTQLMIAA
METFKRGFGTANPVVKGLRALAFALPNKLTFLKRKLAEVALG