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# Ehrlichia chaffeensis str. Arkansas, Arkansas

>ECH_0864 conserved domain protein
MNNTILTIIIIIALIILMIVLLSFIFCAINNRSHKVFFDKQLPNISRDFI
QTIFYPENNNQLNITNLSHKILSNQLAVSMPNLDENLFKQLPRILKFYQS
QDTSNTYINQHFQYIVQSLGIKTNYNNLKTYHPKIALAATLDNMFTVLNN
SEISPDIIHEIVNHFHQEVYEQAGIKILNNIFNTDKNPTNIIKPVNHIIQ
FAVYNYNLITISIISNMSLFDTAKPNKVHSFSSVFHFNMLLRKNPRTNRS
SISYNQTTFTLFIPNSIKHYITKEKCNTQCMQPSSITQDPDCATLHYYNT
SNSHTSTLEYRLPNPKAKPLFQNRRDNIQI
>ECH_0549 hypothetical protein
MHLTLLLLRNGMPVLLPEAACKYDKSLGVAYTMDPIMNEQLGIPTSDSPY
SYLYRSNFTKFAVVSGANSEMNVMFIFGNSPVLSCPVFMVFTLPYGVVRD
VTKNGIMLDNTLIPLHGKVSEDLLGLSTEEQVIKLFNELKSNLKINASSG
QCRMQMFNYVNGNGELFHTSFHNTALDRVTVNPVDGSRRYIMKIE
>ECH_0482 putative lipoprotein
MKFICRMKYAIIIVLFFIILFIPCTSVSVGCVRYDQKDIVVGLISTEFIS
YPNEYKTALGITQLLQSYGVRVVLMDYNVIMQLVKDEIVKINKTYKANCK
ISRYDIIESVVLKFIEEHNINRIFIPGNHYNISSLPIAPSLDRQLVTNAV
VKIIHNQNHCIHLLGVCGGLQGIMYANGIKITRVKDIVNSDISVKSHTVS
MPDPRSVYANLHKIKIFPNTRLSNIAVDLKLAKDQIIYFPDAHSEAIDSN
VENVMKMYNLGYKIAAMSEDGVIEAIEDKYGNIYFQFHPEYLMINAERKF
GDNTSRDTSIMLADAIIKDFLFRD
>ECH_0826 HIT family protein
MQDNTSYDNNNVFAKILRKELPCNVVYEDEFVLAFHDIHPQAPIHILVIP
KGEYISFDDFSDSSADIRHFFSIVKKITHQFQLEKTGYRIVTNHGKQGGQ
IVPHFHVHILGGKQLP
>ECH_0362 putative phosphoribosylformylglycinamidine synthase I
MKKMKVIVLSGYGLNCEEETLFAFVKAGELLSCDVQGKIVHINEVISCPN
LLRDYNVLAIPGGFSYGDDTGAGNAFALRIFHNLREEISEFLAGDKLVIG
ICNGCQILMRLISDFACITLLNNSVRQYQCRWVKVKVNLSNNSPWLKGLN
ELYIPVAHGEGRFFVENVSVISSIEKNIAFRYINNEGNYANQEFPCNPNG
SVADIAALSDNSGKVLVMMPHPERAMFFTQQDNWTQIKEQCLRSNIAYPT
YGDGMKIFCNAVKYFCK
>ECH_0449 cytidine and deoxycytidylate deaminase family protein
MKLAISKAQEDLLEVPVGAVIVHNNEVISSANNSNIHDIDPTAHAEILAI
RNACKILSTHILNQCDIYVTLEPCAMCAQAISFSKIRRLYFGAYNKKYGA
IENGARIFQFCHHVPEVYGGILEAENTKLITDFFKKLRKE
>ECH_0296 putative deoxycytidine triphosphate deaminase
MSVMPDHWIKDKAIKEKMIDPFIDYKRSSGILSYGLSSYGYDARIDNKFK
VFTNVNSVTVDPKNFPLGSFIDKEEDVCIIPPNSFVLAKTVEYFKIPKDI
LVMCVGKSTYARCGIVVNVTPLEPGWEGYVTLEFSNTTPLPAKIYAFEGA
CQFIFLKGDSQCNLSYNEMQGKYMNQLDVTLPIVNNS
>ECH_0351 putative phosphoribosylformylglycinamidine synthase II
MIIRIGVADKVLPKSYKSNDVTVYTINVQHNLSTAIIKKIGSLLTNSITQ
QFFAFTYDTTEQNYKDVSTNTNYNLLDTFKADWSLEKGFLPRVTDNVGNT
TKCIINEMLGYNTATDVLTSKVTFGQGPIPQEENILQLFNPLIEYCKLSF
VTGKTFKVKFFGNKQISNLNNIYADSSTCSSIFIIPYVKYEDLFPQNKKQ
NVTVTSIDLNIQDHELIQISKHGINGRGALNLSLEAMKAIQAYFKKIQRN
PNDIELETLAQTWSEHCKHNIFSSPIDEITDGLYKHYIKRATYEINSEIC
VSTFSDNAGAIVFDDNFIIADKVETHNSPSALDPFGGAITGILGVNRDII
GFGKGAKPILNAYYFCFSESDEELYRDKSCTTKVLSSNTIMDGVIKGVNY
GGNCSGIPTSLGSAYFDNRFRSKPLVFVGCTGIMPRTINKSLSHVKNPNN
GDYIVIAGGRTGRDGIHGATFSSNALTEHNSSSTVVQIGDPITQKKLSDA
IIKEARDLDLYNAITDNGAGGLSSSIGEMGNNGFIVELDKVLLKHDNMSP
WEIWVSESQERMTFAVSPNKFSIFEKVMKKHDIEISIIGEFNNSNKAVVL
FKGSVIMDIDVDFLHNGVPKIHLHTSPWSKTTESIFPKKHNKPLEIELNE
MIQRMNICSKEFISLQYDHEVQGTSIIKPIQGKGRVNGDATVIKPILSSK
KGIVKSHGLGSSYGEISTYHMAACAIDTAIRNYIAVGGNFNHLALLDNFC
WCDSTNPQRLWQLKNAAQACYDYAIAFRTPFISGKDSMFNDFKGYNNKGK
EINISAPPSLLISTLGIIENVENAVTLDVKSPGDLIYILGTTYDELGSSE
YQKYSGLGNNNVPQVHAEHAKKLYISYNKAINTNLIASAIAVNLGGMIIS
LIKSLIGGQLGAEISLSAIPTYNIDNNTLREKVILFSESQSRILVTIGEH
NKQRFEAIFKEVPYANIGKVTSTNTLIIEDICSIDLNILEHNYKKFSNMK
IQSYTNI
>ECH_0688 putative deoxyguanosinetriphosphate triphosphohydrolase
MLDLVKYACNPTETRGRIFHEEEDQYCDCYQRDRDRIIYSGAFRKLQYKT
QVFINYENDYYRTRLTHSLEVAQIARSLSRKLRFNEDLTEAISLAHDLGH
PPFGHAGEDALNEMTMHHLGFDHNIQALRILTFLEKRYIKFDGMNLTWET
LEGVAKHNGPITGENRINSNKKIHKFMLDYDSYYKLDLDNFSSAEAQIAS
ISDDIAYNMHDIDDGIRAKILVIEELLELPLIGDILKKVIDDNSGLSVSD
NRIVHEFLRRTVDIMLMDIISQVTNNIKEYDIRSHDDIRKLGKVFVHFSE
EMNQYKIGLQNFLRTKLYNYYKVKRVKNKVKRIIKELFQVFYDDPQILPS
DWGVKAMDANLIDRSIVICDFISGMTDRFAIQEHRKIFDTTYEMLVF
>ECH_0429 adk, adenylate kinase
MENKINMLIFGPPGSGKGTQCHILSKIYSTISVISTGDLLRSEAKLDTDD
GRKIRQVIESGDLVSDDIVCKMFAKSISRVKSGFLLDGFPRNLSQAEFLT
EILEEYNSRIDIVIQLQLDLETIKNRLYGRIVCKNCGQVSNLNFFDRAID
EIVCKFCKSSQLDYRYDDKVEVIIKRVNQYDREIKKLENYYRDKIVCIDA
GKPIEEVTCDIKDKIAHLIIG
>ECH_0503 carA, carbamoyl-phosphate synthase, small subunit
MSQLTSYYNSILVLSDGKHFFGKSIGKKISTVGEVCFTTSMTGYQHTITD
PSFAGQIITFTFPHIGNVGINYKDFEDRKILTHGIIVKTISEDSHSSSYS
NLELWMIENNLTGISEIDTRALTCHLRQHGSQNGIIYHFDNINSINLAKL
QKKASQYNYRDHCSSISFVNNYNSTDDDTLLYNIVVINFGIKLSILDALS
KLRCKIHMISGNEDNLSEKVLFIKPQGIVLSNGPGDPSAIPENIIKQIKT
IIESKIPILGICLGHQLISLALGAKIIKMLFGHRGSNHPVYNKINNNIEI
TSQNHGFTVKEDSLPTNVQVTHRSLFDNTIEGIQVNDYPIISVQYHPEGS
PGPNDASYIFNHFINLIREND
>ECH_0378 carB, carbamoyl-phosphate synthase, large subunit
MPKRTDIESILVIGAGPIVIGQACEFDYSGTQACKVLKQEGYRIILINSN
PATIMTDPEIADSTYIEPITSNIIEKIIIKERPSAILPTVGGQTALNAAI
NLCELGILEKYNVKLIGATKEAIKKAEDRNLFRQAMDKIGVKYPKSIIIR
SVDEINDALEYIGLPAIIRPSFTLGGIGGGISYNKEEFHKNVSHGLNISP
ISEVQVDESIIGWKEFEMEVMRDNKDNCIVVCSIENLDPMGVHTGDSITV
APALTLRDVEYQKMRDISFSILREIGVDTGGSNVQFAVNPKNDNDLLVIE
MNPRVSRSSALASKATGYPIAKVAAKLAIGYSLDEIQNDCTEVIPASFEP
SIDYIVTKIPRFNFDKFRGTEKELSTSMKSVGEVMAIGRSFPESLQKALC
SLEAGYSGLNEYFDQNIEIDQLYNSLVKLSPDRIFIIADALRHNISIEEI
NKITGYDPWFLTQIKNIIQCEQQIQKNGLPKEAEGLLLLKKMGFSDIRLA
YLSKTTVEYIEDLRKSLSIKPVYKHIDTCAGEFKTNASYMYSCYEGNTIN
VTECESVVTNNKKVIILGSGPNRIGQGIEFDYTCVHAAHTIRQMGYESIM
INCNPETVSTDYDISDKLYFSPLTRESVLDIIYKEQETNSLLGVIVQFGG
QTPLKLAKVLQEKNINILGTSFDSIDLAEDRMKFQQLLTQLNLKQPSNIT
CNSIHEVYECIKDLVFPILARPSYVLGGQSMSIIRDSNALSNYLTTYKNI
FDHGSLLLDQFLTHAIEVDVDAICDGEKVYIAGIMEHIEEAGVHSGDSAC
SLPSYSLTSEITDAIAEQTKKIALALQVRGFINIQYAIQDGEIYILEVNP
RASRTVPFIAKATGIPIAKIATEVLLGKKLPNALEEKLTHVAVKEAVFSF
SRFPNIDVLLGPEMKSTGEVMGIDKSFEIAFAKAQMAAGYELPTKGTAFI
SVKNSDKPLIVKTAQILKDIGFTIFSTKGTSTYLNEAGITTEHVNKVREG
RPHILDLLQDDKINLVINTSEGIKSFSESSSIRKTALIKKIPYSTTIPGA
RALALAIKTLKKQGIHVESMQEYTKK
>ECH_0403 cmk, cytidylate kinase
MTKHCNNFVITIDGPSASGKGSLAKKLANFLNFQYLDTGKLYRIIATIFG
TSAQNHLKIDNKLEDKILSLLLEDNNTIYNNEDIGKTASILARYQHIRLA
LLPIQRKLIHLAEPGIILDGRDTSSTVFPEADLKIFITAQASIRAQRRFK
EMLYHKKEMYKKIHKQILERDIRDTYRKFSPLVKVKDALYINTSYMNKEQ
VLLYIKEKIKTYL
>ECH_0501 dut, deoxyuridine 5'triphosphate nucleotidohydrolase
MEHSIIPNMSIKVIKLTKNNLPLPSYSTDNSSGMDLYSAVVTDVILEPGC
RVCINTGIAISVPNGYEAQVRPRSGLALKFGITVLNTPGTIDADYRGEIK
VILINLGNEAYTIKYGDRIAQMIIAPITRISWDLVEDFDNDKTKRGAQGF
GSTGI
>ECH_0322 gmk, guanylate kinase
MNDSLKSRGIMLVISSPSGGGKTTISHLLINELQNDLVRSISVTTREPRD
GEINGKDYFFVTEPEFINLCNTNQMLEYAKVFGNYYGIPRKFVTDNIANG
VSVLFSIDWQGAFKLIDIMREHVVSIFILPPSMEELQRRLYNRSGESDVI
NKRLGEAAFEISHCYRYDYVIVNHDIEQSVYQIKCIFTSEKLKTQRRVSL
KQFIDNCIR
>ECH_0123 guaA, GMP synthase
MSRVAIIDFGSQFTQLLARRIRELNVYSEIFPHDIAFDYIKDSKAFILSG
GPKSVLDFTGMPPIVHDIIELNKKTSVPVLGVCYGLQLLSNYFNSTIVHG
CGQEFGKAILNVVKKSEMIKDVWKVGDQPYVWMSHADSVYDTPCGFEVIA
CSVVNNAIAMISNEERRIYGVQFHPEVYHTPDGVKLLANFVRIAGCDNNW
TVESFLDEQENLIKKQVGDKKVIAALSGGVDSSVAAALTYRAIGDQLHCI
FIDNGLLRYNEAEKVRQSFVDQFQMPVTIVDRSSVFLDKLQFVTDPEQKR
KIIGKTFIEVFEEEANKIGNVEFLMQGTIYPDVIESGGSVGKESVTIKSH
HNVGGLPDIMKLQLVEPLKLLFKDEVRLLGKKLGISDEILMRHPFPGPGL
AIRIIGEITQEKVNMLQAADEIYINLIKKYNLYDVIWQAFAVLLPVKTVG
VMGDSRTYGYTCALRAVTSSDGMTAECFPFGVDLETKIIFYEFLQDVSNT
IVNNVQGINRVVYDTTSKPPATIEWE
>ECH_0224 guaB, inosine-5'-monophosphate dehydrogenase
MELSYAFDDILIIPSESDVLPSETNVKTYITNEIELRIPIISAAMDTVTE
AKLAIALAQHGGIGCIHKNLPIDTQLLEVRKVKKYESWIVYNPIAVSPDD
SLAVALSIMQEYSYSGIPVVTDTENGKLLVGILTNRDVRFVENKNCKVSD
IMTKDHLITVPEGIERSDAIKLLHQYRKERLIVVDNNYCCVGLITVKDIE
KFNQFPNSCKDSGARLRVAAAVGTGPKDGIERAEALIAEDVDIIVVDTAH
GHSQKVLTTIKEIKTLFPYSQIIGGNIATAEGAHALIEAGVDAVKVGIGP
GSICTTRIVTGVGVPQFSAILNVANACKNKKIKVIADGGIKYSGDIAKSI
AAGADVVMIGSIFAGTDESPGEIIICNGRAYKSYRGMGSVGAMKRGSASR
YFQENNHKFIPEGIEGRVPLKGPVAGVIHQLVGGLRSAMGYTGNRNISEM
KTNCKFTSITSAGLRESHVHDVIITREASNYDPIS
>ECH_1117 ndk, nucleoside diphosphate kinase
MLEKTLSILKPDVIKRNITGQVNSYIENSGLKIIIQKMCLLTRCQAEEFY
AIHKSQHFFVPLIDFMVSGPIIVQVLQGENAISLYREIMGATDPKKASPG
TIRADFAENIDANCVHGSDSLDNAMREIRFFFSDYELLALNG
>ECH_0459 nrdA, ribonucleoside-diphosphate reductase, alpha subunit
MGTVIVDYERDNNLTAFGKAVLSDRYLLENEDYQQLFVRISEYYSDNPEH
AQRLYDYMSQLWFMPATPILSNGGTNRGLPVSCFLNETEDSLRGIVNLWN
ENVWLASKGGGIGSYWGNLRSIGEKVRGSGKTSGIIPFIVVQNALTLAIS
QGSLRRGSSAVYLPVWHPEIEEFLDLRKPTGGDPNRKALNIHHGVVLSNK
FMKCVENDEPWDLISPKDQSVLFTIKARDIWIKILTTRVETGEPYILFID
QVDNNKPEIYKRLNLDIKMSNLCTEITLTTGYDHLNKSRTAICCLASLNL
EYYEQWKDNSLFIEDVMRFLDNVLTDFIEKAPSEMERAKYSAMRERSIGV
GVMGFHSFLQSKMIPFESVAATIWNKKIFSHIRKHADAASYNIAMEKGSC
LDAQDAGIVERFVNKLSIAPTASISIIAGNTSPGIEPYAANVFTHKTLTG
SFIVRNKFLQKLLKLKGKDNEQVWSSISTNEGSVQHLDFLTEEEKLIFKT
AYELDQRWIIEHTSDRSKYICQAQSVNIFLPANVHKRYLHKIHFLAWRKG
LKSLYYCRSKSIQRADKVSHGALEKSIEQYKQITNFDYNECLSCQ
>ECH_0766 nrdB, ribonucleoside-diphosphate reductase, beta subunit
MSLLDSRPIYKPFNYPWAYDAWLCQQRIHWLPEEVPLADDVQDWKTVLSE
KEKNLLVQIFRFFTQADIEVNNCYMKHYSNIFKPTEVCMMLSAFSNMETI
HIAAYSYLLDTIGMPEIEYQAFLKFEVMKKKYDYMQRFEECRKNDKRHVA
KTLAVFGAFTEGLQLFASFAILLNFQRFGKMKGMGQIIAWSVRDETLHTE
SIIRLFNTFIQENYEIWDDSLKQELYEACRIIVSLEDEFINLAFACGDVE
GLSSKEVKEYIRYIANRRLLQLNLEPIYDTNKNPLLWLDEILNGVEHTNF
FENRVTEYARAATEGTWEEAFEDH
>ECH_1024 prsA, ribose-phosphate pyrophosphokinase
MLISSGTSSINLAKCISNITSIKLVNSCISRFSDQELNVEIQENQDDKNK
HVIIINSLCSPAHDNLLELLLLTDAINRTLHPRKITMIIPYLCYTRQDRV
MYRNLDDNSLMVSALSAKVIINILRTANINNIIFIDLHSNQLSGFFDIAT
TNLSSHTVFIGDIIEKHNTNNLVVVSPDYGALNRTRTFANVLSKQCKLHN
EIQVAVIDKYRAKPGVSEVMNITGNVENKDCIIVDDIVDSAGTLCNAASA
LKDRGALQVSAYVTHGILSGNAVEKVTNSKLDNLIITDTIHNGFFNTSKI
RILSIDKFLSNYILYNLV
>ECH_0461 purA, adenylosuccinate synthetase
MVNIVVVGLQWGDEGKGKVVDWLSTNADAVVRFQGGNNAGHTIVINDKVY
KLNLLPSSVLQNNKLSIIGNGVVLDPYALVSEIDNLKSSGINITTQNLAI
SESCPLVLSVHKQADILFEQLRQDTIGTTNKGIGPCYADKISRRAIRVCD
LLDTKDLLYSKVNHLLIYHNLLRKSLNTPPIKAEDIVNELLNIAPKILPF
VQPVWKTIYNLTQQNKTIIFEGAQGTFLDIDHGTYPFVTSSNTIASQAWV
GCGINPSNKSYILGLVKAYTTRVGNGPFFTEQNNDIGKIMFKTGKELGTV
SNRKRRCGWFDAVLARQAIMLSGVSGLVMTKLDVLDQFSEIKICVKYKYG
DKTYDYLPASPHIQSNLEPIYEILPGWQTSTFGSVSYKDLPQNAILYIKK
IEEILKVPIHLISTGPERNSMIILNNDFLQ
>ECH_0852 purB, adenylosuccinate lyase
MIKRYSRPEMSSIWEDNNKFKIWMDIEYYACEAQAKLGVIPDHILNNLKN
KIEHFDINRINEIESVVKHDVIAFLTYISESTNADIRYLHYGMTSSDVLD
TCLSIQLKQSCNLLLDNIEIILNILKQKSIETKYILCMGRSHGVHAEPVT
FGLKLARFYAEFKRNYNRLKMAQDEISVCKISGAMGNFANIDPFVENYVA
NALNLRPESISSQVIPRDRHAMFFATLGVIASSIENIAIEIRHLQKTETL
EVTEYFSAGQKGSSAMPHKKNPILSENLTGLARMIRSYVIPALENVALWH
ERDISHSSVERCIAPDACIVTDFALARLANLLNNMIIYPNNMDKNLAQSK
GLVFSQRVLLELVKYGLKRETAYQIIQERALKTWNNDSHFLDELKKDPQV
LKCISNESLESLFNFDYYTQHIDTIFDKVFKE
>ECH_0290 purC, phosphoribosylaminoimidazole-succinocarboxamidesynthase
MENKEKIYEGKAKIIFATLNPLEVIQHFKDEITAFNNKKAAIIHEKGILN
NYISSFLMKKLIDKGIKTHFISLLNQREQLVKKITIIPIEVVIRNLAAGN
FSKRFQIADGTPFKSPIIEFYYKNDELSDPMVSEGHILSFQWLTNQELEK
IKILSLKINNILSELFFNVGIKLVDFKLEFGKLHNDEQSDLFLADEISPD
TCRLWDISTNKRLDKDRYRLNLGNVIEGYREVAHKLNAIPNL
>ECH_1006 purD, phosphoribosylamine--glycine ligase
MNVLVIGSGGREHSMLHHIRKSTLLNKLFIAPGREGMSGLADIIDIDINS
TIEVIQVCKKEKIELVVIGPETPLMNGLSDALTEEGILVFGPSKAAARLE
SSKGFTKELCMRYGIPTAKYGYFVDTNSAYKFIDKHKLPLVVKADGLAQG
KGTVICHTHEEAYNAVDAMLVHHKFGEAGCAIIIEEFLEGKEISFFTLVD
GSNPVILGVAQDYKTIGDNNKGPNTGGMGSYSKPNIITQEMEHIIIQKII
YPTIKAMFNMNIQFRGLLFAGIIIKKNEPKLLEYNVRFGDPETQSILPRL
NSDFLKLLSLTAKGKLGNESVELSKKAALCVVVASRGYPGEYKKNSIING
IENIEKLPNVQLLHAGTRREGNNWVSDSGRVINVVAQGENLASAKHQAYA
ALDLLDWPDGIYRYDIGSCAL
>ECH_0160 purE, phosphoribosylaminoimidazole carboxylase, catalytic subunit
MSTNKNIADVAVIMGSQSDFSTMNNSISILKELNITHEVMIISAHRTPER
LYTFAKSAEDNGFKVIIAGAGGAAHLPGLVASLTHIPVIGVPVKSSNLNG
IDSLLSIVQMPKGIPVATMSIGSSGGYNAAIMAASILSLENDEIRKNLKI
WRKNLSDSVKLIPDIPL
>ECH_0139 purF, amidophosphoribosyltransferase
MQFNEIYEECGVFAIQNNNCAAINCILGLHALQHRGQESFGIVTSEDNKL
HFHYSNEQVNSIFNQQSKIDSLLGNTAIGHIRYSTSGSKVGVQPITLDCK
FGKLAIAHNGNLTNAAQIRKSLTERGCIFSSDIDTEVIAHLIAINTENTL
LDNVINALKTIKGAYSLVILINGTIICCRDPAGIRPLVLGMLDNSYIVAS
ETCALDIVGAQFIRDVLPGEFITIDQGNTLTSSFPFKKQKSSFCIFEYVY
FARPDSIIDNKSIYEIRKNIGKELAIENPIPKDTHMIVPVPDSGVPAALG
FAEYTKIPFEFGIIRNHYIGRTFIQPNDHIRSMGVKLKHNANSSILKDKV
IVLIDDSLVRGTTLKSIITLLHKAGVQQIHLRISSPPTINSCFYGIDTPE
ESKLIANRLSQLEIKNALGCDSLHFLSIDGLYKAICNTKRNNSIPQYCDA
CFTGDYPIGKIE
>ECH_1074 purH, phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
MKIKRAIISVYNKTNIIELAKFLIEQKVEIIATSSTYKALLDAGLQVTEV
SSYTKFPEIMDGRVKTLHPKIHGGILSNRNTHAAECLKLDIHDIDLVIVN
LYPFSQVANNKTSTENEIIEQIDIGGVTLLRAGAKNFHNVTVISDINDYD
TLKAEMINNQNSTNLTYRKQLAKKAFAITSSYDSSIYNWLNKDSKDILPE
TLVIHGNKVQDLRCGENPHQKGAFYSTLGDKYPLKQLHGKELSYNNIVDI
ESAINIVTEFTQPAAVIIKHSNPCGAATADDITTAYNKAFACDPKSSFGG
IVALNREINEDIAEEINKIFIEVIVGPSITDKAMEIIQKKKNVRIMLSTE
YNPPKYIIKNVSNGFLLQESNTNQLSEKDLIQVTNFPVSDDTISNLLFAW
KICKHVKSNAIVIAKDHRAIGVGAGQMSRVDSLEIAIKKAQDCAGAVLAS
DAFFPFTDSILLSASVNISAIIQPGGSLRDQEVIEEANNKKIAMFFTNIR
NFYH
>ECH_1034 purK, phosphoribosylaminoimidazole carboxylase, ATPase subunit
MLHDSYIGPGSTIGIIGGGQLGKMISIAAANLGYKTHLLTNNPDDPSVYI
TNSATISHNYQNTESLLEFASNVDIATLEFENIPTTTIDILSQKIKVYPG
KEALYISQNRIREKQHIRNLGIKTSDFRVIDNYNSLVKNTIELGYPTLLK
TTELGYDGKGQYIIKQQDDLSALSTLNWDQSYILEKFVKIYKEISVIITK
SISGSIEFFPTAENCHTDGILTTSSVPALISQEINVQAQKIALQIAESIN
LVGLLAVEFFITDTQELIVNEIAPRPHNSGHWSLDACNISQFEQLIRAIC
GLPLKPVKLLFPCIMNNILGDNIHNYYKHETKVNENLYIYGKKKATKNRK
MGHINTLKFNQ
>ECH_0342 purM, phosphoribosylformylglycinamidine cyclo-ligase
MKTYSSAGVNIESGNSLVEKIKPIASSTSIPGVVDSIGSFGALFDISRIK
EYNKPVLVSSTDGVGTKLCIAQGVDNHKTIGIDLVAMCVNDVLAQGAEPL
FFLDYFATGKVNHDTALEIINSIAVGCKKANVALIGGETAEMPGMYSDNK
YDLAGFAVGIIEADNILPKSHNIKVGDKILGLASSGLHSNGFSLIRKIIS
DNKINYHDVCPWSNQTWANYLLTPTRIYVKSLLSTIPLVNGLAHITGGGF
TYNIPRIIPSHLSATIDLSSWKMPEIFHWLNTEVQIQQTELLKTFNCGIG
MILVTSQENEDQVLSLLKVTDEVVYKIGEITERNTEDQVIFK
>ECH_0370 purN, phosphoribosylglycinamide formyltransferase
MTPLKLGILISGRGSNMQALINACAQDDFPAEVSCVISNNPKANGLLIAQ
KQNIKTFVVQGRPLDFDSIDSILRQHQVDLICLAGFMSIVPEGFINKWFH
KIINIHPSLLPSFKGLNAQSQALKAGVKIAGCTVHYVYPEVDGGPIIVQA
AVPVFSSDNLTDLSERILKMEHICYPKAVKLIALNQLQLNENLATSAELL
HMFYDETI
>ECH_0621 pyrB, aspartate carbamoyltransferase
MKTLLEVSNLTSDDIESIFNLTIQYFNNTNLNHNILTGKVIVNLFFESST
RTLSSFEIAEKSLGAHSITLNINTSSINKGESIIDTISNIDAMNPDLIII
RSQYSQFIKKISEYLPSCSIINAGDGHHEHPTQALTDYCTIRYIKKDINN
LNISICGDILHSRVARSNIRLLSRYGANISLVAPPTLSCNLTGISHIYHN
LIEGIRNADVIMLLRLQKERIINCVIPSEQEYSHLYMLNHEKLLHAKKDV
IVMHPGPTNKGIEISNNVAEKNSVILLQVKMGVAARKAILHYLLYNKSI
>ECH_0373 pyrC, dihydroorotase, multifunctional complex type
MYKQSWELLGNGQHADLTVAYINARIIDPESKLDIRGSLLTKGDKIIDFG
PDLFANGIPSTIDEVIDCNNNILLPGLIDIHVHFREPGQEHKETINTGSK
SAAAGGITTVVCQPNTIPTISSVITAKYIKMRALESAYVNIEFYASITKS
DNSLSDMALLKEVGAVGFTDDGMPVMNALTMRQALSYSSMLDTVIAQHAE
DLNISNNGCINEGIISYELGLKGIPDISESIIVNRDIALMKNIKNVHYHI
LHVSSQESLHIIKQAKSQGLKVTCEVTPHHFTLTERDIMTHGSLAKMNPP
LRTENDRLSMIEGLKSGIIDCIATDHAPHDINAKELPLDTAAFGIVGLET
MLPISLELYHNGTMPLIDLLATLTYKPADIIKVPRGRIKKDYVADLIILD
LDHEWVVDISKFASKSKNSPFHNRKVKGKVLRTIVSGKTTYKAEIII
>ECH_0940 pyrD, dihydroorotate dehydrogenase
MSLQHIFTNPLFCIPPEIAHKLVIFALKNNFIPTKKIEIPRSLNIQVFNK
LLRTPIGVAAGFDKNAEVIQPLLSIGFGFVEVGTVTKHPQNGNKKPRVHR
LISKEAIINSLGFNNKGINFLIKKVNNIQLNHCIFGINIGFNKKSSDPIQ
DYFDSVKKVYGLSNYITINISSPNTPGLDEFQKKDLLSELLTAISQVRKL
ADYAESVPIMLKISPDINDNKKQDIVDLAIKYKISGLIISNTSSQHNKLL
NMNTNIHGGLSGKPLFDLSTQVLSEIYQASQGKLLLIGCGGVSTGYHAYE
KIKAGASLVQLYTAIVYNGFNIANKISLELADLLAADGFPTVRHAIGHNH
>ECH_1108 pyrE, orotate phosphoribosyltransferase
MEADLLNSDSIYGEFTKIGVIISGHFVLSSGLHSDTYIQCARLFENPVIA
VKFCALLATKIGKVLPNIDLIVSPAVGAITVGYEIARQLGINNVFCERVN
GLFTLRRGFEIKKGSKVLIVEDVITTGKTSMEVVSCVKKNGGTVVAGAAL
VKRSRDIKLPFPIISLVELNIKSYVDEDVPEYLRKIPVSVPGSRYLQEN
>ECH_0792 pyrF, orotidine 5'-phosphate decarboxylase
MFTNPIICALDTHDINHALLLTKMLYGRVSMVKLGLEFFTAYGLSGVQAI
ADCGVPIFLDLKLHDIPNTVSKAISVIASLNVAMLTIHVSGGREMMIRAM
DSISGSVTKLVGVTVLTSMDDSDLKEIGVNESPVQQVMLLSKLAREVGLY
GIVCSAFEAKEVRNRYTEKDLKLIVPGIRFDSDCNDQKRVKSPKDAMLAG
ANYLVIGRPITMSSDPVQTVEDILLSISKCI
>ECH_0171 pyrG, CTP synthase
MNQASTRFIFVTGGVVSSLGKGLAAASIGALLQARGFKICLRKLDPYLNI
DPGTMSPIQHGEVFVTDDGAETDLDLGHYERFTGVKTTKNDNITTGKVYH
NLLKKERRGDYLGQTVQIIPHVTDLINSFILHDTDKLDFVICEIGGTVGD
IESQPFLESIRQIGYKLSKNNTIFVHLTLVPYIDAAMELKTKPTQHSVKE
LSSVGIQPDIILYRSKIPLSKEQRDKIANLCNVSSTNIIPALDVKNIYEL
PISYHNYNLDTQILNHFNIDSPEPDLRKWENILNISHAVTKTVNVAIIGK
YIKLLDAYKSLIEALEHASIHNKVKLSIKWIDSRSLDSNEINIFDKVDSI
LIPGGFGDDGIQGKMTAITYARLNKIPFLGICMGMQLAIIEFANNVAHLE
DANSTEFNLYCKNPVIHQLPELQQNFLGGSMKLGSCPCYLESGSKIFSIY
QQSIIHERRRHRYAFNLQYKDLLEQHGLIFTGKSNNNNDSLIEVIELKDH
PWFIGVQFHPEFKSSPFHSHPLFISFIKASLD
>ECH_0266 pyrH, uridylate kinase
MSEASATKVKYSRVLLKVSGEALMGKKGFGCDIEVLDKLSHDLKEVHSFG
VQLCLVVGGGNIFRGASASASFGFERASNDYIGMLATMMNALSLQNALEK
VNVQSRVLSAIPITAVCETYIRRRAIRHLEKGRVVICAAGVGSPFFTTDT
AAALRGIEMGCDAIFKGTQVDGVYSADPKKNADAVRYDKISYRDLLSLDL
KIMDVAAVSLAREHSVPIIVFNLGQPGSFADIIRGDGLYTTIYN
>ECH_0317 thyX, thymidylate synthase, flavin-dependent
MIDYMGSDESIVQAARISYGRGTKSVSQDAALINYLMRHSHTTPFEMCEI
KFHIKLPIFVARQWVRHRTANVNEYSARYSVLDHEFYIPEHSQVAMQSED
NAQGRGNNLSDEDAKYVADLLTRDSDMVYETYNKFLEKGVSREIARVNLT
LNYYTEWYWKIDLHNLLHFLKLRSEMNAQYEIRVYAETMLDIVKKWVPLT
YAAFVEYCLKSQNFSRSALDVVKKLIVGEKVVQEDTNIGKREWRELMAIL
KPE
>ECH_0229 tmk, thymidylate kinase
MFITFEGIDGSGKTTQSHLLAEYLSEIYGVNNVVLTREPGGTLLNESVRN
LLFKAQGLDSLSELLFFIAMRREHFVKIIKPSLMQKKIVICDRFIDSTIA
YQGYGQGIDCSLIDQLNDLVIDVYPDITFIIDVDINESLSRSCKNGYEFA
DMEFYYRVRDGFYDIAKKNPHRCHVITDKSETYDIDDINFVHLEVIKVLQ
MV