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# Thiomicrospira crunogena XCL-2, XCL-2

>Tcr_1906 deoxyuridine 5'-triphosphate nucleotidohydrolase (dut)
MTMQVQYKILDPRLGKEIEMPHYGTKGSAGLDLRACIENDMIIEPGQTVL
IPTGMAIHLDDPGLAAMLLPRSGLGHKHGIVLGNLVGLIDSDYQGPLMVS
CWNRSEEAYNVTVGERIAQMVIVPVLQPVFTQVEEFGDATERGEGGFGHT
GSH
>Tcr_2051 formyltetrahydrofolate deformylase
MSRVFRLIISCPDQVGIVAKVAGFIASEGGSIIEANHHTDALNQWFFMRH
EILASSLKNDLDGFKTKFAAIAADFDMDWQITDSDQPKKIALFASKESHC
LADLLYRWHENDLPGEVACVIANHDDLRRMVEWYDIPFHHVPVTPDTKTE
AFAKSQQLVAQYDVDVIVLARYMQILPPQMCLDYAGRVINIHHSFLPSFV
GAKPYHQAYERGVKLIGATCHYVTEELDAGPIIEQDVIRVSHSQSIDDMR
RLGRDVEKTVLSRGLRYHLEDRVLIHGNKTVVFDN
>Tcr_0808 amidophosphoribosyltransferase
MCGIVGIVSNSPVNQEIYDALTVLQHRGQDAAGIVTCDNGRLYQRKDNGM
VKDVFRTRHMRDLRGNMGIGHVRYPTAGSASSAEAQPFYVNSPYGIAMGH
NGNITNAEQLSKEIYEQDLRHLNTNSDSEVLLNIFAHELMQQKKLFIDPE
DIFNAIHRVHKRARGGYAAVGIIPSMGLFAFRDPFALRPIVVGKRETSTG
VDYMVASESVALDAAGFELLKDLEPGEAVVMTEQGTVQFKQCADSPQYSP
CIFEFVYFARPDSMIDDISVYKSRLRMGEKLAEQIMRDWPDNDIDVVMPI
PDTSRTSALQLADKLGKPYREGFIKNRYIGRTFIMPGQKQRKKSVRQKLN
PVTLEFEGKNILLVDDSIVRGTTSGEIVQMARDAGAKKVYFASAAPAVRY
PYVYGIDMPSASELVANGREINEIADYIGADKLFYQDLDDLIEAVWQGNK
SIKEFDTSCFSGCYVTGDITQEYLDSLDKTRNDDAQSKQKEVGQEPVGIY
NGG
>Tcr_2130 Adenosylhomocysteine nucleosidase
MKVAIIGAMEEEVALLRNQIQNLKTEIHGGFEYYLGQINAIDVILLRSGI
GKVNAAIGTALLIKLYEPDYVINTGSAGGFHTDLEVGDIVISQSVCHHDV
DVTPFGYARGQVPGHPECYLADIHLIDIAKRSIDALQEVTHMHGLIATGD
RFMHLPEDVATTREYFPDMIACEMEAAAVAQTCHAFETPFVIIRSLSDIA
GKENAVTFEQYLDKAATHSARLILEMLTHLKS
>Tcr_1889 Allantoinase
MKTILITQAKIVNEGKIFEADVLIKDGLIEKIAPKLDVSADTVIDAQGQH
LLPGFIDDQVHFRDPGFAAKGSIATESKAAIAGGTTSFMDMPNVKPTTTT
LENLEAKFDLASKTSWANYSFYLGATNDNIEEVKALDPNQACGVKIFMGA
STGNMLVDREKALTDIFTHSPTLITTHCEDTPMIQAQEAIYREKYGEDVP
MKYHPDIRCREACYKSSSFAVDLAKKTGADLHVLHLTTAEEMALFEPGPV
AGKKITAEACVHHLWFAQEDYEAQGSLIKCNPAIKKVSDRDAIRQAVRDG
RIDIIATDHAPHTWEEKQNKYFTAPAGLPQVQQSLTALLDMVHQGVFDLE
TVVQKTAHNVAIRYEIKDRGYIREGYAADIVLVDMNKPHTDNKADNLYQC
GWSPWEGHTFKSSVMTTIVNGDIKYHQGQFSEFIPGQRLAFDRS
>Tcr_1818 phosphoribosylaminoimidazole carboxylase, ATPase subunit
MTPVTKKIGVLGAGQLGRMLAIAGYPLGQKFGFLGASHEEPSALLGHMYT
EKDEASSLSDLIAFSDVMTYESENTSVDLVRKIAETTPVFPAEKSLYYSQ
HRGREKGMFDSLNIPCAPYQVVDSLESLTQAVDQIGLPAVLKTTTEGYDG
KGQFVIKETTQIDQAWKEIGGRELILEGFVDFSRELSIVAVRNADNQHVY
YPLVQNVHHEGILRYTIAPARQISEDVQTQAEQYMKALLDELDHVGVLTL
ELFETVDGLVANEMAPRVHNSGHWTIEGALTSQFENHIRAITGLPLGDTS
PRQEIAAMVNIIGETGPVKDVLTMPKAFLHLYDKAERAGRKLGHINLLAD
SEDELYQQINQLSAFLPKV
>Tcr_1763 Ribonucleoside-diphosphate reductase
MSCNEKHTYSTFCRSSNNALKEPMFFGQNVNVARYDQQKHPIFEKLIEKQ
LSFFWRPEEIDLSSDRGEYANLPEHEKHVFISNLKYQTLLDSVQGRSPNV
ALLPLVSIPELETWIETWSFSETIHSRSYTHIIRNIVSDPSLVFDDIVAN
EEIVKRAISVTVYYDKLINLTNRMYAEEIDLETNDAFRKEIKTALFLTIV
SVNVLEAIRFYVSFACSFSFAERSLMEGNAKIIKLIARDEALHLSGTQHL
INILSEGKDDPEMMEIAKENEEKVYEIFREAAEQEKEWADYLFKDGSMIG
LNASILKDYVEYITNTRIKAIKLNPIFENKSNPLPWMNNWLVSDNVQVAP
QESEISSYLVGQVDSTVDKDDFNDFAL
>Tcr_1352 formyltetrahydrofolate deformylase
MSASYVLTVSCPDKIGIVSKVSTFLADHQCMITEANHHADEELGMFFMRN
EISNLNMSEESFKLKFLDIAQQFDMQWKLSSGAKKKRVIIMVSKQDHCLY
DLLYRWKSGEMDYDIPCVISNHLDLKGLVEWHGIPYVHIPVTPDNKSQAF
SEVVKWVEHYQADTIVLARYMQIIPPDLCRKYPGQIINIHHSFLPSFIGA
RPYHQAFERGVKLIGATCHYVTEELDAGPIIEQDVRRVSHSESADEMVVL
GKDVEKNALARGLKHHLEDRVLLSGNKTIVFA
>Tcr_1950 dihydroorotate dehydrogenase family protein
MASGNAGYGIEYQAVSGFSNRDVGAVFLKGTTLEPKLGNKPERVMETASG
LLNSIGLQNPGAHAVIKDYLPKLDLSQSQFIINVSGSSIEEYAEVVRLFD
QTDLPAIEVNISCPNVKKGGAAFGNDPDMAAKVVEACRANTSKPLIVKLS
PNQTDIAEGARRVIDAGADMLSAINTLMGMQIDIHSARPTLGNNQGGLSG
PAIKPVALLKVHQVYQVAKQHNVPIIGLGGIASADDAIEFLLAGASMVAV
GTAMAKDPLLVKKINQGIEKYMARYGYQSVAEMTGKLILNTDTVLCG
>Tcr_1892 Ppx/GppA phosphatase
MTDTTESQNIYAAIDLGSNSFHMMVAREVHGQLQVIDKHKEMIRLRSGLD
KKGYLTPEAFQSGIECLERFGQLIKNIPGHQVRAVGTNTLRNAKNSQEFL
RQARKVLGHEIQIIAGQEEARLIYLGVAHGLPQNDEQRLVMDIGGGSTEY
IIGKNFNYQHLTSTEMGCVSITQQFFSKPEITEKRMTKAISNCRQILRPH
LTKLTNLGWDSAIGASGSIKSIGTLLKENGWTEGEITLEGMLKLKEALIQ
AGSIQAATLLGLKEERIPVLAGGLAILIATFEELKIAQMQVSSNALREGL
VFDTLGRLFAEDVRETSVAAAQAWLKIDTEQAEAIAHTTKTFYKQAHNSW
QLHDADYNYKKLLIWAAQLHEAGMALSYKRYRHHSAYLIENSELAGFTQQ
EKQMLSTMLLNHRGKFVPEAYERFASPHKEKLKYLTVLLRLAVRIHRGRE
KDIPDILLYTTGEKTIHLAFEKDWLTAHPLTQMDLEIEAERLAGADFILT
YE
>Tcr_1549 Sulfate thiol esterase
MSLNRREFLHVMSMAAAAGMLPGTASAMSTSPDYKGAPASMDMYNLPMKG
KVRLLHITDTHAQLKPIYFREPNVNLGTGPAFGKLPHVVGHKLLKELNIK
ENTPLAHAFTYLNFQDASEQYGKVGGFAHLKTLLDKLRESAGGRENTLLM
DGGDLWHGSGTALWTRGADMVEASNLIGVDVMTGHWEFTYKENEVLTNLN
NFKGEFLAQNIRVKEDSLFGDSYRDMVDRHNGTGLYDEDEGRAFKPYTIK
IINGERIAIVGQAFPRTANANPQSNFPDWSFGLREDALQETVNEIRETKK
VAAIVMISHNGMDVDLKMASRINGIDAIFGGHTHDGIPKTTPVKTPEGGV
CHVTNAGSNGKFVGCMDLDIQNGKLRGVNYNLLPVFSNILPADETVQTFI
DHLYTKVYDKSIVESRDPSRAYNKDRLGKTYGDILNEELAVAEDTLYRRG
NFMGTWDQIIVNSLREEHDAQIAMSAGVRWGTSVLAGEMITMERVMDETS
MTYGETYKSEVTGAQMKDILEGICENLFQKDPYLQSGGDMVRLGGMDYTC
EPNATLGNRISDMRLDDGTPLEANKTYSVAGWAQVESVGDGRLMWDVAAD
YLRNHKNDMKLKKVNHPKLKGVKNNPGIEDYPGEMA
>Tcr_1201 orotidine 5'-phosphate decarboxylase
MNQSVQPDPKVVVALDFPKTQLAEDFARHLDPQLCRLKVGKELFALGGPQ
LVEKLITQGFEVFLDLKYHDIPNTVAMACRAAAEMGVWMVNVHSLGGRKM
MEAAKEAVLSASHQPLLIGVTILTSMETEDLAEIGLTGTPKENVLRLAKL
AHSSGLDGVVSSAQEASDLRKEIGQDFCLVTPGIRPANADVNDQKRIMTP
ADAMAAGSSYLVVGRPITQAKDPIAVLNEINASIGR
>Tcr_0108 Phosphoribosyltransferase
MLCHKYKKLIMKQHPLAQYLEAVPDFPKEGILFQDISPLLRDHFVATIDA
MSLLFSAKEWAEVDYLVGVESRGFIFASALALKHDKGFVKVRKPGKLPNV
HASMEYGLEYGTDKLEMQKGNGKKVIICDDLIATGGSMQAAAKLCNEVGY
EVVGMACLVDLKALNSFSHDGMTVRSVIQFDD
>Tcr_1615 GMP synthase
MSQNNIHEHRILILDFGSQYTQLIARRIREIGVYCEVEPWDIDVEDIVKF
GARGIILSGGPETVTGDNAPVAPVEVFELGVPVLGICYGMQTMAEQLGGK
VINATEHEYGYAQVRAHGHTKLLNDIEDHVTPEGYGMLDVWMSHGDRVDK
MPEGFKLMASTGNCPIAGMANEEKDFYGIQFHPEVTHTTQGQRMIERFVV
DLCGCEKLWTTENIIDDSIARIRQQVGSDEVLLGLSGGVDSSVVAALLHK
AIGDQLTCVFVDHGLLRHQEGDQVMSMFAENMGIKVIRVDAEDYFMNALA
GEADPEKKRKIIGHAFIEMFDQESAKLTGVKWLAQGTIYPDVIESAGSKT
GKAKVIKSHHNVGGLPEDMKLELLEPLRELFKDEVRRLGVALGLPSDMVY
RHPFPGPGLGVRILGEVKKEYADILRLADHIFIEELRAADLYDKTSQAFT
VFLPVKSVGVVGDARRYDYVVSLRAVETIDFMTARWAHLPYDFLEKVSNR
IINEIPRITRVTYDISSKPPATIEWE
>Tcr_1045 phosphoribosylglycinamide formyltransferase
MTTKMRIAVLISGKGSNLQALIDQASQSRYEIGLVLSNRPHAKGLQKAEK
AGIPTAILDHSQFDSREAFDTAMIQIIDSHKIEAVILAGFMRILTPIFTD
HFLGRMLNIHPSLLPKYPGLNTHQRALEAHDKEHGLSIHFVTSELDGGPV
ILQAKVPVTQGDTVDSLQKKVQVQEHIAYPLVTNWLASGDLIFKNNQAWY
KNTHLTTPIQLTEL
>Tcr_1829 aspartate carbamoyltransferase
MRLSTPNLQLNEQGKLRHFLTIEGLKQHHLTEILDVAESFINPVTGDISK
VPSLHGKTIMNLFFEPSTRTLTTFEIAEKRLSADVVNLNIETSSTKKGET
LLDTLWNLEAMLADVFVVRHSESGAAHFIAKHVAPHVHVVNAGDGQHAHP
TQAMLDMFTIRKHKGDIFDLKVAIIGDVQHSRVVRSQIQALSILEAREIR
VIGPKTLMPSHPEALGVHVYDHIEEGLDGVDVIINVRLQNERMKSALLPS
EKEFFNLYGLTKERLSYAKPDAIVMHPGPVNRGVEIDSEVADGHQSVILE
QVTYGIAVRMAVMSIIIDNAKQLNADKQITKKVTEEARS
>Tcr_0438 phosphoribosylamine--glycine ligase
MNVLIIGSGGREHALAWKTIQSDKVSKVFVAPGNAGTALEDNIENVDIAV
EDLPGLVDFAQKNAIELTIVGPEVPLVLGVVDAFQDAGLKCFGPSKGAAQ
LEGSKAFSKDFLAKHNIPTAAYSVFTEIPPAVAYIEKMGAPIVIKADGLA
AGKGVILAETNAEAIAAVEDMLAGNKFGDAGARVVIEEFLVGEEASFIVM
ADGKNILPMATSQDHKARNNGDTGPNTGGMGAYTPAPVVTRKIHDRIMQE
VIRPTIDGMAKDGLPYTGFLYAGIMIAEDGTPKVLEFNCRFGDPETQPIM
MRLQSDLSELCLAALDKKLDTVTAKWDSRPALGVVLAAGGYPDEYRKGDI
IEGIEDANNTDVKVFHAGTRLDEQGQLVTSGGRVLCVTALGENVTDAQKR
AYEGVAKIHWNEVYYRTDIGHRAVKREAIS
>Tcr_1342 Glutamine amidotransferase class-I
MKVLILQHTATEGAGVILDWCSQKGADVSYIKLYEPQPHFVLGDSFQLVV
VLGGPMSVNDESGYPWLKMEKSYIAQCIDAQIPVLGICLGAQLIASSLGA
KVMANSEPEIGWHNVDAVSNEDADVFQFPASLSVFHWHGETFELPFGAIH
LAESAGCANQGFQLGDKVIGLQFHPEITSSTIDVWIKDAGESLKHSMYVQ
TADEMTSQAKAFLPSSKAFLFDVLDYLVK
>Tcr_0081 DNA/RNA non-specific endonuclease
MSKNTSHLTQLLFKELAKQPKLLQISFFWLPVIFGFVLLAGGLKYVYETE
VARPAMAYMGVPKSNHDWSNLTHTLRNKGFMLAYSERLANPIWVTYKVTP
TKVKYGKRPHFQADWRSLAHIRHEDYTSSGYDRGHMAPNYVIASRYGYEA
QKETFLMTNITPQKPSFNQKIWQRLEEVSADVFSKQVGTFWVVTGPIFDA
KPNTLKKAPVAIPKAFYKIFIRPEIDGKPTIALAFILPQTAKPKDSLLNY
VTTIDQIEQQTGIDFFWQLEDTLETALEASKNPQAWSLEKVANLPSRY
>Tcr_1283 Uridylate kinase
MSLKYARVLLKFSGEALMGQGQFGLDSNTLRQVVLEVKALRDLGVEVGLV
VGGGNIFRGAQIEGAGIQRTTGDHMGMMATVINALALRDVIEDMGMSSVV
YSAMAIEGVSHGFNANHVKKGMAEGQVAIFAAGTGSPFFTTDTAAALRGI
EIDADIVLKATKVDGIYTADPAKDSSAQRLAELTYDDVIQKNLQVMDMTA
FVLCRDHKMPIRVFDMFKKDAVIRIVKGEDEGTLVH
>Tcr_0850 Ham1-like protein
MMSPIILATNNPYKVAEIAPIMNRAGLVTQCQADFFNEEVVEDELSFVEN
ALKKARFASERTGLPALGDDSGLEVNALGGRPGLFSARYAGGEQKPSDEE
NLKKLLNDMTQLPYPQRQARYSCAVVYVENAQDPMPLIGIGHWYGEILMR
PRTGAGIGYDDVFWIPKLLKSVSEIPFELKNQISHRARAVQSVVQQLTER
GGR
>Tcr_2138 Guanylate kinase
MAGSLYIISAPSGAGKTSLVSKLTEKDSRIQVSISSTTRPKRPGEEDGVN
YVFLSVDAFKQKVAENDFLEHAQVFDNYYGTSKSVVESKLAEDKDVILEI
DWQGAQQVRKLIPDAVSVFILPPSLKELEKRLRGRGTDSEDVIERRMSDA
VNEMKHFNEFDYLVINNHFDTALSELHSIFLANRQACAKQYEKHSVMINE
LTQQH
>Tcr_1079 Deoxyguanosinetriphosphate triphosphohydrolase
MHQAHQEERDWTQRYTDFLEGKASREARIVYQRDRARVIHSASFRRLQAK
TQIFGLNESDFYRTRLTHSMEVAQIGSGLVEQLITVGEGQDYMGWLPSFY
LIEAICLAHDLGHPPYGHGGEVALNYMMRRHGGFEGNAQTLRILSRLGEY
TPQNGIDLSRRATLGVLKYPAIYDEVVALNKDYQIQMQEKDAFDFRTLDM
SRWYPPKASVYLEEKEQFEWVLGMFSEADKKLFTQLKPDDKGFHKTQYKA
LDTTIMELADDIAYGIHDLEDAVAMGMVSRDLWQAEVMENPVFQAHPLWD
NTMSERLFSSRSKDRKHAISKMVGIMVESIYMDENTVFEHPLLRYQAKLG
ASEMAVLELLKTFVYIHVITLPEVKGMEYKGQLIVLDLFKSLRANPEALL
PRNTYTKFISSESEREQLRVLSDYIAGMTNTYASRMYEKFFTASQGSIFD
RI
>Tcr_1550 phosphoribosylformylglycinamidine synthase
MQIIWGNSAHSEYRLNQLLNKLSKVGRISSLKSQFIYAVDLNEDAPALSV
SDLTKLGVLLNDTETDLTSEFDETACVVTPRLGTISPWASKATDITHTCG
IETIHRVERGIVYFLEGVASEDRAAMEALLFDRMVEQVFHSLDDLKGLFS
HQSPKAYQTVDVLSGGAEALQKANSEMGLALSEDEIDYLVSAFKGLERNP
VDAELMMFAQANSEHCRHKIFNADWTIDGADKPNSLFGMIRNTYQKNPQG
VLSAYSDNAAVVEGYKATRFFPNPETRQYQYSDESVHFQIKVETHNHPTA
ISPWSGAATGSGGEIRDEGATGRGSKPKAGLTGFTVSNLNIPGFKQPWES
VYGKPSRIVSPLEIMIEGPLGAAGFNNEFGRPAINGYFRTYENALITHDG
EEVRGYHKPIMLAGGLGSIREQHIQKNDIPVGAKLVVLGGPAMLIGLGGG
AASSVDSGAGSETLDFASVQRENPEMERRAQEVIDRCTYLGDQSPIASIH
DVGAGGLSNAFPELVNDAGRGGKFQLRDIPNDEPGMSPMEIWCNESQERY
VIAIYPDQIEQFEAICQRERCLYAIVGEATEEQKLVVNDTVFDNNPVDMP
LNVLLGKPPKMHRTVESRLIPQPGFEPAVLDFNDVTERLLKLPTIANKSF
LITIGDRSITGMVTRDQMVGPWQVPVANAGITCADYQGYTGEAMATGERP
PVALINPKASARLSIAEAITNIACAKIEKMSDIKISANWMAAAGHPGEDS
ALYDAVETVGLELCPALGIAVPVGKDSMSMKTVWQDGEESKSVTSPVSLN
ITTFAPVQDVRKTVTPQLRTDLGETVLLAIDLSRGQNRLGGSCLAQVYNQ
VGDVSADLDSAEDLLNLFNFVQALMADELMLAYHDRADGGFLVTLLEMAF
AGHCGLALDTSALGEEAISALCSEEVGVVVQVKADDKAAVEALLDSYRLS
DAAHWVGSPSDSDQIEIMAHGKTLLKGPRKTYQAWWSETSYRMQALRDNE
ECAKQEFDAIQQDTNTRILPVVTFDQNDDITAKFSRTNRPKVAILREQGV
NGQQEMAAAFDRAGFEAIDVHMSDVLSGEVSFDDYRGLVACGGFSYGDVL
GAGRGWANSILFNETARQTFEGFFKREDTFTLGVCNGCQMLSNLKEIIPG
AESWPKFVRNESEQFEARFSLVEIQESPSILLKGMAGTRIPVAVAHGEGR
MDFGQRSAQEVDGLVGVRYVDSAGNPTEAYPFNPNGSEAGMTGLTTTDGR
VTIMMPHPERVFRTVQNSWHPDDWLEDAPWMRLFRNARKWVG
>Tcr_1262 CTP synthase
MTKFIFVTGGVVSSLGKGIAAASLGSLLEARGLKVSMLKMDPYINVDPGT
MSPLQHGEVFVTDDGAETDLDLGHYERFVQRNFTKRNSFSTGQVYEKVIR
NERRGDYLGGTVQVIPHITDEIKHRIKLAAAGADVALVEVGGTVGDIESL
PFLEAIRQLGVEVGRDRAMFMHLTLLPYIAVAGEVKTKPTQHSVKELRSI
GIQPDILICRSERPLEESEKRKIALFTNVEEKAVINSLDARTIYEVPRML
HEQGLDRLVTDRFRIDAPVADLSDWDDVVQAQLNPEKSVEIAMVGKYVDL
TEAYKSLIEALIHGGIQTKTQVNIHYIDSEDLEKDGIGSIEKMDAILVPG
GFGERGVEGKIAAIQFARENNVPYLGICLGMQMAVVEFARHVAGLPSAHS
TELDPKTKTPVVALITEWTDENGQLVERDEKADLGGTMRLGGQSCALVEG
SKMRDIYGEDVIRERHRHRYEVNDGYIAKLEAAGLKISGRSEDGNLVETV
EIEDHPWFVACQFHPEFTSTPRNGHPLFKAFVEAASQHKQTTH
>Tcr_0879 carbamoyl-phosphate synthase, large subunit
MPKRSDLESILIIGAGPIIIGQACEFDYSGVQACKALKEEGYRVVLVNSN
PATIMTDPEMADATYIEPIEWKTVRNIIAKERPDAILPTMGGQTALNCAL
DLDNHGVLEEFGVELIGANADAIDKAENRDRFRQAMNRIGLDMPVSDVAH
NLEEAWEIQQRVGFPTIIRPSFTLGGSGGGIAYNKTEFEQICKFGLDLSP
TKELLIEESILGWKEYEMEVVRDKNDNAIIICSIENLDPMGVHTGDSITV
APAQTLTDKEYQIMRNASLAVLREIGVETGGSNVQFSINPESGRMIIIEM
NPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELSNDITDGATPASFEP
SIDYVVTKIPRFTFEKFPQADKRLSTQMKSVGEVMAMGRNFQESIQKAMR
GLETGKNGFDEIMPLATMDEKEVKDILRQELRAPGPDRLWYVADAFRAGW
SLETVFDISKIDPWFLSQIKQLIDMEDDIKQRGLDALDEHVLRSLKRKGF
SDNRIADLLDTDAAFIRKFRHTLNIRPVYKRVDTCAAEFETSTAYMYSTY
EEECEANPTDREKIMVLGGGPNRIGQGIEFDYCCVHAAMAMREDGYETIM
VNCNPETVSTDYDTSDRLYFEPLTLEDVLEIVEVEKPKGVIIQYGGQTPL
KLAEDLEAAGVPIIGTSPESIDLAEDRERFQQLLHGLELKQPPNRTARSE
DQALALANEIGYPLVVRPSYVLGGRAMEIVYNDTDLTRYMTEAVKVSNDS
PVLLDRFLDDAIELDVDAVCDGEQVVIGGVMEHIEQAGIHSGDSACSLPP
YSIPMHIQDEIRNQVEKMALGLNVVGLMNTQFAVKGEDIYVLEVNPRASR
TVPFVSKAIGSPLAKIAARCMVGQKLAAQNFTKEVRPTYFSVKEAVFPFI
KFLGVDPILGPEMKSTGEVMGVGETFPEAYQKAQLAGGTILPTSGKAFLS
VRQADRVKVIDLAKKLIKKGFTILATRGTAKSLEEAGIECEIVNKVTEGR
PNIVDSIVNEEVDLIVNTSDGSVSIKDSSSIRREALMHKTCYTTTMAGAL
AMVASMDYLDNQKVTKLQAD
>Tcr_0463 Ribonucleoside-diphosphate reductase
MSTETMNVAKRNGETEPLDLEKIHRVITWAAEGLENVSVSEVELRSHIQF
YDGMKTSDIHETIIKSAADLISESAPDYQHLAARLAIFHLRKKAFDRFTP
PTLFEHVNKMVRNRLYDPQIQDDYTKAEFDELDNYIQHDRDMNFSYAAVK
QLEGKYLVQNRVTGKIYESPQFIYMLIPMSLFAHYPNDAEPGKTRLDYVK
RFYDAASNFKLSLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSSI
VKYVSQRAGIGVNVGQIRALGSEIRGGEAYHTGMIPFIKHFQTAVKSCSQ
GGVRGGAATLFFPIWHLEVESLIVLKNNRGVEENRARHLDYGVQVNKLMY
QRMIEGGNITLFSPSDVPGLYDAFFEDQEEFERLYKIYEADDTIRKKTMK
AVDLFTQVAQERAQTGRIYIQNVDHSNTHSSFDPKKAPIHQSNLCLEITL
PTHPLNSVDDPEGEIALCTLSAFNLGALEDLDELDELSDLIVRALDSLLD
YQDYPVEAARKASMGRRTLGVGVTNLAYYLAKNHVKYSDGSANNLVHKAF
EAIQYYLLKASLNLSKEYGKCDFFEDTKYAQGILPIDTYKKELDEFCTEP
LHYDWETLRSEIQKHGLRNSTMTALMPCETSSQITNSTNGIEPPRGYVSV
KASKDGILKQVVPGFKEFRDQYELLWQIPDNKGYLQLVGIMQKFVDQAIS
ANTNYDPAKFEDGRVPIKLVLQDLLYAYKAGLKTLYYHNTRDGADDSHED
DGCAGGACKL
>Tcr_2058 adenylate kinases
MKFILLGAPGAGKGTQAQFLTKEFNIPQISTGDMLRAAIKAQTPMGKMAK
EFMDAGKLVTDEIIIGLVKDRIAEPDCANGFLLDGFPRTVPQADALKAAG
VEIDAVIEIDVPDSEIVNRMAGRRVHPASGRTYHITYNPPKVDDKDNETG
DDLIQREDDKAEVVLDRLKVYHEQTAPLIGYYKAEAEKNDQLKYIQVDGT
QPIDTVEKSILSALK
>Tcr_0392 ribose-phosphate pyrophosphokinase
MAYKNVRLFAGNANVSLAESISSSIEIPLGKADVGRFSDGEIMVQINESV
RGKDVYVLQPTCTPEPAVNLMELLVMIDALKRASAKRITAVVPYYGFARQ
DRRPHSARVPITARLAADMITVAGADRVITVDLHADQIQGFFDIPVDNIY
GSPTLVADMRASGHIAEDNMMVVSPDMGGVVRARAVAKALGCEMAIIDKR
RPKANVAQIMNIIGDVSGRDCILVDDMVDTAGTLCKAAEALKEHGANSVT
AYVVHAVLSGPAVDNINKSCLTELVVTDTIPLSEAGLASEKIRRVSVASV
LGETIRRVHQEESVSELMPIR
>Tcr_1895 orotate phosphoribosyltransferase
MNKSEFIEFIMQAGVLKLGEFTLKSGRKSPYFFNAGLFNTGGQMAQLAKA
YAATIAESKLAYDVLFGPAYKGIPLAATTSVSLAQDFQQDTPYAFNRKEA
KDHGEGGNIVGHPLEGNILIIDDVITAGTAIRESMDIIQANGARPAGVVV
ALDRMEKGQGEKSAIQEVEQEYGIPVISIINLNDIIEYLETHNQANQEIL
DSMKTYRAQYGIAH
>Tcr_0439 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
MKPVRRALISVSDKNGILEFAKSLTAMDVVILSTGGTYKVLSEAGLPVTE
VSEYTGFPEMMDGRVKTLHPKIHGGLLGRRGTDDAVMAEHGIDPIDMVVV
NLYPFEATVAKPDCSLEDAIENIDIGGPTMLRSAAKNHKDVAVVTDPHDY
ARILEEMESNDGQLSHATRFDLAIKTFEQTARYDGAISNYFGTMFSDDKD
DTFPRTYNTQFVKKQSMRYGENPHQSAAFYTERNPTEASISTAKQLQGKA
LSFNNIADTDAALELVKTFEETACVIVKHANPCGVSIGENVFESYDRAYK
TDPTSAFGGIIAFNRALDQETAQAIIDRQFVEVIIAPNVSEDAKNVIAAK
QNVRLLVCGDLGIQEPAYDYKRVTGGLLVQDRDLGSVTEDELKVVTKRAP
SEKEMADLQFAWKVAKYVKSNAIVYVKDGMTIGVGAGQMSRVYSAKIAGI
KAADEGLEVPGSVMASDAFFPFRDGIDAAAEAGITAVIHPGGSMRDQEVI
DAADEHGIAMVFTGMRHFKH
>Tcr_1046 phosphoribosylformylglycinamidine cyclo-ligase
MTKNNQSISYKDAGVDIDAGNALVEAIKPIAKATARPEVSTSLGGFGALF
ELPMDKYKNPLLVSGTDGVGTKLRLAIESGKHDQVGIDLVAMCVNDLIVQ
GAEPLFFLDYYATGKLDIYTARDVVAGIGEGCQQSGCALIGGETAEMPGM
YPDGDYDLAGFCVGIVEKADLIDGTKVKAGDVLLGLASSGPHSNGYSLIR
KIIEVNGANLNEECDGQPLIDALMAPTRIYVKSILALMKQIEIHAISHIT
GGGLLENLPRVMPNNTKAKVDTKSWNRPAVFDWIQTHGNVEFHEMHRTLN
CGIGMVVVVDEKDQQAAIDALTAQGEVVSVIGKIESSESETPEVDLV
>Tcr_2054 Ham1-like protein
MKTVILATGNAGKLAEMRAILAPLNLLVQSQAEYFSDEAVEDGLSFIENA
ILKARFASAKTGLPAIADDSGLEVDFLQGRPGIYSARYSEGYQGQAASDA
LNNQKLLDELDGVSAENRQACYYCAMAYVRHKDDPTPLIGLGQWCGTVLD
APIGSGGFGYDPLIWMEEEGCSVAELSKAVKNKISHRAKALQALVAQLK
>Tcr_2132 phosphoribosylglycinamide formyltransferase 2
MLQIGTTFSKTATKILLCGAGELGKEVAIEAQRLGLEVIALDRYENAPAM
QVADRSYTLSMLDGEALRHIIEKEKPDYIVPEIEAIATDTLAKLEQEGFN
IVPSAKATQLTMNREGIRRLAAEDLGIPTSPYAFADNKEDFTAAVDAIGI
PCVVKPIMSSSGKGQSVIKSTADIDSAWHYAQEGGRAGKGKVIIEGFVDF
DYEITLLTIRHKNGTSFCAPIGHIQEDGDYRQSWQPHPMSDIAVQSAEKI
ALKITEALGGWGLFGVELFIKDDQVIFSEVSPRPHDTGLVTLISQDLSEF
ALHLRAILGLPIPNITQHGPSASSVILPTGHSTETQFSGLEDALKEPDTQ
IRLFGKPEIAGRRRMGVALARDTSIEKAIEKAKASAMAVKVDF
>Tcr_1971 Histidine triad (HIT) protein
MTPEKSIFSKIIDREIPSEIVYEDEKCIVINDINPKARIHLLVIPKKPIA
TLFDLAPEDKDLMGHMMLLLPQLAQSQGLDGFKTQIHTGESGGQEVFHIH
IHLLGN
>Tcr_0718 Thymidylate kinase
MSNTQSNTSYSGKFLTLEGTEGGGKSTNLVFIQQWLADHNIDVVVTREPG
GTAVSEAVREILLDKQYSEMTPETELLLMFAARNQHLQEKILPALAAGKW
VVSDRFTDASYAYQGGARGIAYDRIAEIENWVQQGCYPDMTFVFDLPIEE
GMKRVAARSKLSGQAIDRFEQEKMEFFEKVRAAYLYRAEQAPQRYCVLNA
ARPLNEVQEKLASQLESLL
>Tcr_1508 hypothetical protein
MDTIITDHTPKNLEEKFENRFLYQTGDYSLMCEETKIPWLQIIPNRALDE
AYVATLYGEIYRLAEYLKEKGLGPHYNVAKIGNKLPYYHIHLVFRKTDDE
VWPEPIWGKDLQPDLTQTNQFHSLLSGFYS
>Tcr_0878 carbamoyl-phosphate synthase, small subunit
MTHTALLALEDGTLFWGISLGAEGETVGEVVFNTSLTGYQEILTDPSYYK
QIVTLTYPHIGNVGVNEEDEESPSIMAQGLIVRDCPPLMSNFRAQKSLPD
YLKEQGVVAISDIDTRKLTRILRDKGAQSGVIVAGENIDADAAIAKAKTF
AGLKGMDLAKEVTTSETYVWTEGTWSLENGHTDCASKSEYHVVAFDYGIK
RNILRMLADRGCKLTVVPAKTPASEVLAMKPDGIFLSNGPGDPEPCDYAI
QAIQEVLRTDIPVFGICLGHQLLALASGAKTVKMKFGHHGGNHPVQDLKT
KKVMITAQNHGFAVDADSLPDCLEATHSSLFDGSSQGIQHKDKAAFSFQG
HPEASPGPHDVAPLFDQFIENIKKYKQA
>Tcr_1197 cytidylate kinase
MTSSVVTIDGPSGVGKGTLAQFLCCKTGFHLLDSGAIYRSLAYGALEEGI
AFDNLPGLVVLAENLPVKFVENSILYREKDITSKVRTEEVAAVASKVAAI
PEVRAALLKRQKDFAQPPGLIADGRDMGTVVFPNAPVKLFLTASAEERAK
RRVKQLKNQGVDVNIRQITQDIMERDERDRTRKSSPLVPAEDALEIDTTH
LSIEEVCQMALNQLYDAGLMK
>Tcr_1830 dihydroorotase, multifunctional complex type
MRLLIENARIIDPSQKMDQVSNLYISRGRILKISDTDPEGFTPDQVIDGT
GKWILPGLVDLHARLAEPGSRYEGNIASETKAAVSGGITTICSPPDTNPV
NDTQAVTELIQRRARQAATAFVLPIGALTQGLEGKMLSNMAALKNAGCIA
LSQASQPIQNPLTLKNAMAYAASNEILLMLRCEDTELKNNGVVHSGVISS
RLGLSEIPASAETAALARDLILAEETGARVHFSQISTARSLEMIADAKKR
GMPVTCDVAIHQLHLTEYDVMDFDSLFHVTPPLRTHDDKEALRLGVKMGI
IDAIVSDHTPLDRDVKLLPFGESEPGISGLETLLPLTLRLVEEGVLDLNT
AISALTQRPADILGIHNGSLIEGHYADFSLFNPETPWTLNRSEMVSQGDN
SPFHGWEFTGQIETTYFQGRPVYRNNQV
>Tcr_1094 adenylosuccinate synthetase
MVKKNIVVVGTQWGDEGKGKIVDLLTDRVAAVVRFQGGHNAGHTLVIDGK
KTVLHLIPSGILREDVECFIGNGVVLAPEALEKEVAQLEDTGLKVKHRLK
ISDACPLILDYHVALDQARELARGNKAIGTTGRGIGPAYEDKVARRGLRA
GDLKNMSQLKQKLQTAMEYHNYMLTNYYKAEPVDFETLWAKCQAYADLIV
PMLADIPNLIDLYNKEGKNLMFEGAQGTLLDIDQGTYPYVTSSNTTAGGA
ASGSGIGPCQLDYVLGITKAYATRVGGGPFPTELRYDVATDEGDAVGKEL
GTRGREFGATTGRQRRCGWFDAVALRRSAQVNGLTGVCLTKLDVLDELEE
IKVCTKYRKDGQDVFLPPSSADEYELVEPHYETLKGWNTSTVGIDSWDAL
PEEAKVYIRFLEKEMGVTVSILSTGPDRSETLVLEDPFEV
>Tcr_0572 Thymidylate synthase
MKQYLDLLKHITETGVAKGDRTGTGTRSVFGYQMRFNLEEGFPLVTTKKL
HLKSIVYELLWFLNGDTNNQYLKEHGVRIWDEWATETGDLGPIYGRQWVA
WEKPNGDTINQIEEVIQTLKKNPNSRRMLVSAWNPADLPDESMSPQENVK
QGRMALATCHAFFQFYVANGKLSCQLYQRSADTFLGVPFNIASYALLTHM
IAQQTDLEVGEFVWTGGDVHLYNNTLEQAELQMSRTPYALPKLKIKRKPP
SIFDYEFDDFEIEGYESHPHIKAVVSV
>Tcr_1819 phosphoribosylaminoimidazole carboxylase, catalytic subunit
MSTAKTGSNIPLVGVIMGSKSDWPTMEKAVEMLEEFGVAHEVKVVSAHRT
PDLMFEYAAEAEARGLQVIIAGAGGAAHLPGMVAAKTIVPVLGVPVQSRA
LSGQDSLLSIVQMPGGIPVGTLAIGEAGAKNAGIMAAQIVGNQNATVREK
VRAFREAQTQFVLENPDPTIP
>Tcr_0262 phosphoribosylaminoimidazole-succinocarboxamidesynthase
MQPLFESNLTSLPLINKGKVRDLYDIDENHLLIVTTDRISAFDVVLPTPI
PGKGRILTETAQFWMKKASHILPNQLADDMQLSDVLTPDELLQLDGRGMI
VRKLTPLPVEAIVRGYLVGSGWKEYKKTQTVCGIELPKGLKKAQQLPEPL
FTPSTKAEIGDHDENISFEEVVKLIGEKKAQKVKEYSLALYKMAAEFAAE
RGIIIADTKFEFGEDEHGVIHLIDEALTPDSSRFWPAKTYQVGKNPDSFD
KQYIRDYLESLDWDKTAPGPELPEEVVDMTFQKYQEAQARLMENP
>Tcr_1043 Deoxycytidine triphosphate deaminase
MKLSDRDIIQHLKIGKIGIDPMPEQHKIKGISVDLRLANKFRVFNDHTAP
FIDLSGASDEMQKMMDIIMGDEVVIEEGQAFFLHPGELALASTFESVSIP
DDLVGWLDGRSSLARLGLMVHVTAHRIDPGWQGQIVLEIFNSGKLPLALR
PGMDICAINFETLSSAAIKPYNKRADAKYRNQKGPTASRITQDQTSHQDE
RQLDLLS
>Tcr_0619 Nucleoside-diphosphate kinase
MLERTFSIIKPDAVKRNLIGQIVSKLEQNGLKVIASKMVFLTVQEAKGFY
AEHDGKPFFDTLIKNMTAGPIVVQVLEGDDAIAKNREIMGPTDPENAPAG
SIRKEYAISMQQNSVHGSDSPESAQREISYFFSEIEVFSAS
>Tcr_1614 Cytidine/deoxycytidylate deaminase, zinc-binding region
MLTVSETLSPSEQDIFWMTHALSLAKKAEQQGEIPVGAVLVKDSKLIAEG
WNQTIQAHDPTAHAEVVALRKAGIEEENYRLNDLTLYVTLEPCPMCAGAM
VHARLKRLVIAAKDFRTGAAGSLINLVQEPRLNHQVKTDFGVLESEASEM
LSGFFRKRRLEKKKAR
>Tcr_1137 adenylosuccinate lyase
MQLSELTAISPIDGRYGARLSSLKEIFSEYGLIKNRVKVEVSWLRMLANH
PGIPEVPPLSSDAENHLLKLVDEFSLEMAQRVKDIERTTNHDVKAVEYLI
KEHFGDNAELNAIGEFVHFACTSEDINNLAYALMLKDARATVIVPEMQTL
VDKISGMATEMADIPMMSRTHGQPASPTTAGKEFANVAYRLQRQIKQLMN
VQIMGKINGATGNYNAHLAAYPSINWYELTEQFVQSLGLAWNPYTIQIEP
HDYIAEYFHTMQRFNTILIDFDRDIWSYISIGFFKQKTVAGEIGSSTMPH
KVNPIDFENSEGNLGIANAIFDHLGQKLPISRWQRDLTDSTVLRNLGVGV
AHTMISLQATLKGLNKLDVNAQAMADDLDNNWEVLAEAIQTVMRRYGIEK
PYEKLKELTRGRRVNKQIMQEFVDTLELPEEAKQSLKQMTPASYIGNAAQ
QAQNIELALTMLKGR