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# Streptococcus pyogenes M1 GAS, SF370

>SPy0121 putative deoxyguanosine kinase/deoxyadenosine kinase(I) subunit
MLIVLAGTIGAGKSSLAAALGEHLGTDVFYEAVDNNPVLDLYYQDPKKYA
FLLQIYFLNKRFKSIKEAYQADNNILDRSIFEDELFLKLNYKNGNVTKTE
LDIYQELLANMLEELEGMPKKRPDLLIYIDVSFDKMLERIERRGRSFEQV
DGNPSLEQYYHQVHGEYPTWYEDYEVSPKMKIDGNSLDFVQNPQDLATVL
KMIDTKLKELHLL
>SPy0025 putative phosphoribosylformylglycinamidine synthase II
MSSYFPVAPLSDLVSYMNKRIFVEKKADFGIKSASLVKELTHNLQLTSLK
ALRIVQVYDVFNLAEDLLARAEKHIFSEQVTDCLLTETEITAELDKVAFF
AIEALPGQFDQRAASSQEALLLFGSDSQVKVNTAQLYLVNKDITEAELEA
VKNYLLNPVDSRFKDITLPLEEQAFSVSDKTIPNLDFFETYQADDFATYK
AEQGLAMEVDDLLFIQNYFKSIGCVPTETELKVLDTYWSDHCRHTTFETE
LKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMATIFGRYER
ANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITTPIAETRAGKLPQQVI
SKTAAHGYSSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVV
REKPEAGDVVILLGGKTGRDGVGGATGSSKVQTVESVETAGAEVQKGNAI
EERKIQRLFRDGNVTRLIKKSNDFGAGGVCVAIGELADGLEIDLDKVPLK
YQGLNGTEIAISESQERMSVVVRPNDVDAFIAACNKENIDAVVVATVTEK
PNLVMTWNGEIIVDLERRFLDTNGVRVVVDAKVVDKDLTVPEARTTSAET
LEADTLKVLSDLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTESSV
QKLPVQHGVTTTASVMAQGYNPYIAEWSPYHGAAYAVIEATARLVATGAD
WSRARFSYQEYFERMDKQAERFGQPVSALLGSIEAQIQLGLPSIGGKDSM
SGTFEDLTVPPTLVAFGVTTADSRKVLSPEFKAAGENIYYIPGQAISEDI
DFDLIKDNFSQFEAIQAQHKITAASAAKYGGVLESLALMTFGNRIGASVE
IAELDSSLTAQLGGFVFTSAEEIADAVKIGQTQADFTVTVNGNDLAGASL
LAAFEGKLEEVYPTEFEQTDVLEEVPAVVSDTVIKAKETIEKPVVYIPVF
PGTNSEYDSAKAFEQVGASVNLVPFVTLNEVAIAESVDTMVANIAKANII
FFAGGFSAADEPDGSAKFIVNILLNEKVRAAIDSFIEKGGLIIGICNGFQ
ALVKSGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRIANTNSPWLAG
VEVGDIHAIPVSHGEGKLVVSASEFAELRDNGQIWSQYVDFDGQPSMDSK
YNPNGSVNAIEGITSKNGQIIGKMGHSERWEDGLFQNIPGNKDQILFASA
VKYFTGK
>SPy1984 putative ribonucleotide reductase (NrdI protein)
MPQITLVFISLSGNTLSFVKRLSLYLADNYDYHVKQINIKDLKHETFPVK
EEFVAILPTYLEGGNGVDSGDVEILTTPLGEFIAAHGNAQRCLGIIGSGN
KNFNHQYCLTAKQYAKRFGFPLLGDFELRGTPDDISRLAQVIMEASSRHS
SNDTQTLPNS
>SPy1135 putative GMP reductase
MFNDIPVFDYEDIQLIPNKCIITSRSQADTSVTLGKYQFKLPVIPANMQT
IIDETIAEQLAKEGYFYIMHRFDEDSRKPFIKRMHEQGLIASISVGVKAC
EYEFVTSLKEDAPEFITIDIAHGHANSVIDMIKHIKTELPETFVIAGNVG
TPEAVRELENAGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKA
ARKPIIADGGIRTHGDIAKSIRFGASMVMIGSLFAGHFESPGKTVEVDGE
TFKEYYGSASEYQKGEHKNVEGKKILLPTKGHLSDTLTEMQQDLQSSISY
AGGKDLDSLRHVDYVIVKNSIWNGDSI
>SPy1211 hypothetical protein
MKRDDLMQIIKRDGHVADFDPDKIYQAIIKAARTVYVIDDTWRQNLTHVT
KKVVIDLEEAHVERPTINMVQSLVENRLMDAGYITIAEHYISYRLQRDLE
RNGYGDKIVVHLRFEQIK
>SPy0872 putative secreted 5'-nucleotidase
MKKYFILKSSVLSILTSFTLLVTDVQADQVDVQFLGVNDFHGALDNTGTA
YTPSGKIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPA
NSALLQDEPTVKVFNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPEST
INDITKQYEHEASHQTIVIANVIDKKTKDIPYGWKPYAIKDIAINDKIVK
IGFIGVVTTEIPNLVLKQNYEHYQFLDVAETIAKYAKELQEQHVHAIVVL
AHVPATSKDGVVDHEMATVMEKVNQIYPEHSIDIIFAGHNHQYTNGTIGK
TRIVQALSQGKAYADVRGTLDTDTNDFIKTPSANVVAVAPGIKTENSDIK
AIINHANDIVKTVTERKIGTATNSSTISKTENIDKESPVGNLATTAQLTI
AKKTFPTVDFAMTNNGGIRSDLVVKNDRTITWGAAQAVQPFGNILQVIQM
TGQHIYDVLNQQYDENQTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKD
NGEEINLTTTYTVVVNDFLYGGGDGFSAFKKAKLIGAINTDTEAFITYIT
NLEASGKTVNATIKGVKNYVTSNLESSTKVNSAGKHSIISKVFRNRDGNT
VSSEVISDLLTSTENTNNSLGKKETTTNKNTISSSTLPITGDNYKMSPIM
TILALISLGGLNAFIKKRKS
>SPy0362 hypothetical protein
MSEKIYEYKDENNWFIGKMTGHNLISGWGVKHTTIKKIDDLLDGIAATLD
WENPKGYDVSVVRHQSPLSLITFIIDMINQETQREIKVTPHAGTILLMEN
AKLLAVYLPEGGVSTATFFATSEQGFGDIILIATRNEGKTKEFRNLFGQL
GYRVENLNDYPELPEVAETGTTFEENARLKAETISRLTGKMVLADDSGLK
VDALGGLPGVWSARFSGPDATDAKNNAKLLHELAMVFDQKKRSAQFHTTL
VVAAPNKDSLVVEADWPGYIATQPKGENGFGYDPVFIVGETGHHAAELEA
DQKNQLSHRGQAVRKLMEVFPAWQAKQS
>SPy1137 putative purine permease
MTHSTKQEHSHSQSAVLGLQHVLSMYAGSILVPIMIAGALGYSARELTYL
ISTDIFMCGVATFLQLKLTKHTGVGLPVVLGCAFQSVAPLSIIGAQQGSG
AMFGALIASGIYVILVAGIFSKIARFFPPIVTGSVITVIGLSLVGVAMGN
MGDNVKEPTAQSMMLSLLTIVIILLVQKFTKGFVKSISILIGLVAGTLVS
AMMGLVDTTPVVEASWIHVPTPFYFGMPTFEITSIVMMCIIATVSMVEST
GVYLALSDLTNDQLDEKRLRNGYRSEGIAVFLGGLFNTFPYTGFSQNVGL
VQISGIKTRRPIYYAAGILVVIGLLPKFRAMAQMIPSPVLGGAMLVLFGM
VALQGMQMLNRVDFQKNEYNFIIAAVSISAGLGFNGTNLFASLPETAQMF
LTNGIVIATLTSVVLNLVLNGKDKQDE
>SPy0095 putative histidine triad (HIT) protein
MTECIFCHQLKANQLLTQSQYFKVVFDIDPIQKGHLLLISKDHYTSLTQL
PKEGHYDLIDLQAALVAKLEQHLPISGVTSVSNDKELMDEGTHFHLHLIP
RLTNDSFWEGITINQENWDLTPFLKHL
>SPy0235 putative dUTPase, phage associated
MTKIRGFELVSSFTNPDLLPKRETTHAAGYDLSVAEAVTIAPGEIKLVPT
GVKAYMQDGEVLYLYDRSSNPRKKGIILINSVGVIDADYYGNEANEGHIF
AQMQNITDHPVTLAVGERIVQGVFMPFLIADGDQARGERTGGFGSTGQ
>SPy1345 hypothetical protein
MDWLIGYGVKEMISTGTCGVLVPIAENRFLVPVKALRDEGTSYHYVAPSR
YIDIDPKMLRLIEKTLLAQGLAYQEVITWSTDGFYRETKEKVAHRQEEGC
SVVEMECSALAAVAQLRGILWGQLLFTADTLADVEVYDQRNWGADSFSFA
LHLCLEVLNTLEKDGKATDF
>SPy0074 adk, adenylate kinase
MNLLIMGLPGAGKGTQAAKIVEEFGIAHISTGDMFRAAMANQTEMGRLAK
SYIDKGELVPDEVTNGIVKERLAEDDIAEKGFLLDGYPRTIEQAHALDAT
LEELGLRLDGVINIKVDPSCLVERLSGRIINRKTGETFHKVFNPPVDYKE
EDYYQREDDKPETVKRRLDVNMAQGEPILEHYRKLGLVTDIEGNQEITDV
FADVEKALLELK
>SPy0927 apt, putative adenine phosphoribosyltransferase
MDLTNYIASIKDYPKAGITFRDISPLMADGKAYSYAIREIAQYACDKDID
MVVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPRDVVSADYEKEYGLDT
LTMHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGIVAGCAFLIEL
EGLNGRHAIRNYDYKVLMQFPG
>SPy0833 carA, putative carbamoyl phosphate synthetase small subunit
MTKRLLILEDGTIFEGEPFGADIDVTGEIVFNTGMTGYQESITDQSYNGQ
ILTFTYPLIGNYGINRDDYESISPTCKGVVVSEVSRLASNWRKQMTLDAF
LKIKGIPGISGIDTRALTKIIRQHGTMKATMADDGDSIQHLKDQLRATVL
PTNTIEQVSTKTAYPAPGIGKNIVLVDFGLKHSILREFSKRQCNITVVPF
NITAEEVLQLNPDGLMLSNGPGNPEDLPEALDMIRGVQGKIPIFGICMGH
QLFSLANGAKTCKMTFGHRGFNHAVREIATGRIDFTSQNHGYAVERSSLP
DTLMVTHEDINDKTVEGVKHRDFPAFSVQFHPDAAPGPHDASYLFDEFLE
MIDSWRCTSK
>SPy0835 carB, putative carbamoylphosphate synthetase
MPKRKDIQKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYKVILVNSN
PATIMTDKEIADKVYIEPLTLEFVNRIIRKERPDAILPTLGGQTGLNMAM
ALSKAGILDDLEIELLGTKLSAIDQAEDRDLFKQLMQELDQPIPESTIVK
TVDEAVTFARDIGYPVIVRPAFTLGGTGGGICSSEEELCEITENGLKLSP
VTQCLIERSIAGFKEIEYEVMRDSADNALVVCNMENFDPVGIHTGDSIVF
APTQTLSDIENQMLRDASLKIIRALKIEGGCNVQLALDPYSFKYYVIEVN
PRVSRSSALASKATGYPIAKLAAKIAVGLTLDEMINPITGTTYAMFEPAL
DYVVAKIPRFPFDKFEHGERQLGTQMKATGEVMAIGRNLEESLLKACRSL
EIGVCHNEMTSLSNISDEELVTKVIKAQDDRLFYLSEAIRRGYSIEELES
LTKIDLFFLDKLLHIVEIEQELQMHVDHLESLKKAKRYGFSDQKIAEIWQ
KDESDIRAMRHSHSLYPVYKMVDTCAAEFDAKTPYFYSTYELENESVQSN
KESILVLGSGPIRIGQGVEFDYATVHSVKAIQKAGYEAIIMNSNPETVST
DFSVSDKLYFEPLTFEDVMNVIDLEQPKGVIVQFGGQTAINLAQALSEAG
VTILGTQVEDLDRAEDRDLFEKALKELGIPQPQGQTATNEEEALEAAKKI
GFPVLVRPSYVLGGRAMEIVENKEDLREYIRTAVKASPEHPILVDSYIFG
KECEVDAISDGKSVLIPGIMEHIERAGVHSGDSMAVYPPQQLSKQIQETI
AEYTKRLAIGLNCIGMMNVQFVIKNEQVYVIEVNPRASRTVPFLSKVTGI
PMAQIATKLILGQTLKDLGYEDGLYPQSPLVHIKAPVFSFTKLAQVDSLL
GPEMKSTGEVMGSDTSLEKALYKAFEANNSHLSEFGQIVFTIADDSKAEA
LSLARRFKAIGYQIMATQGTAAYFAEQGLSACLVGKIGDAANDIPTLVRH
GHVQAIVNTVGIKRTADKDGQMIRSSAIEQGVPLFTALDTAKAMLTVLES
RCFNIEAI
>SPy1230 cdd, putative cytidine deaminase
MGTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIENVSFGL
TNCGERTAIFKAISDGHKELVEIAIYGETMQPVSPCGACRQVMAEFFDPS
SLVTLIAKNGQTVEMTVGDLLLYSFTDLI
>SPy0803 cmk, putative cytidylate kinase
MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYIALTHGY
TGKEVALILEELEKNPIFFKKAKDGSQLVFLGDEDVTLAIRQNDVTNNVS
WISALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASV
EERAERRYKENLEKGIESDFETLKEEIAARDYKDSHRKVSPLKAAEDALI
FDTTGVSIDGVVQFIQEKAEKIVDMS
>SPy1823 comEB, putative late competence protein required for DNA binding
MTNRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGYNGGVSA
TDNCNEAGHYMEDGHCIRTVHAEMNALIQCAKEGISTDGTEIYVTHFPCI
NCTKALLQAGITKITYKAHYRPHPFAIELMEKKGVAYVQHDVPQIVLGGD
KEQ
>SPy1867 deoC, putative deoxyribose-phosphate aldolase
MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPASYVKKAA
EYVSGKLAICTVIGFPNGYSTTAAKVFECQDAIQNGADEIDMVINLTDVK
NGDFDTVEEEIRQIKAKCQDHILKVIVETCQLTKEELIELCGVVTRSGAD
FIKTSTGFSTAGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAKTFIALG
ASRLGTSRIIKIVKNEATKTDSY
>SPy0894 deoD2, putative purine nucleoside phosphorylase
MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNMFGYTG
TYKGHRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHV
RELVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHV
GNVLSSDVFYTNMPERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIM
TISDNLNDPTEDTTAEERQTTFTDMMKVGLETLIAND
>SPy1213 fhs.1, putative formate-tetrahydrofolate ligase
MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEKMKAVEA
NEPGKLILVTAINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGP
VMGIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLQQ
GNDLGIDPRRIIWKRVLDLNDRALRQVIVGLGSPVNGVPREDGFDITVAS
EIMAILCLATDLKDLKKRLADIVVAYTYDRKPVYVRDLKVEGALTLILKD
AIKPNLVQTIYGTPALIHGGPFANIAHGCNSVLATSTALRLADYTVTEAG
FGADLGAEKFLNIKVPNLPKAPDAIVIVATLRALKMHGGVAKSDLAAENC
EAVRLGFANLKRHVENMRQFKVPVVVAINEFVADTEAEIATLKALCEEIK
VPVELASVWANGAEGGLALAKTVVRVIDQEAADYKRLYSDEDTLEEKVIN
IVTQIYGGKAVQFGPKAKTQLKQFAEFGWDKLPVCMAKTQYSFSDNPSLL
GAPTDFDITIREFVPKTGAGFIVGLTGDVMTMPGLPKVPAAMAMDVAENG
TALGLF
>SPy2085 fhs.2, putative formate-tetrahydrofolate ligase
MVLSDIEIANSVTMEPISKVADQLGIDKEALCLYGKYKAKIDARQLVALK
NKPDGKLILVTAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLG
PVFGVKGGAAGGGHAQVVPMEDINLHFTGDFHAIGVANNLLAALIDNHIH
HGNSLGIDSRRITWKRVVDMNDRQLRHIVDGLQGKVNGIPREDGYDITVA
SEIMAILCLSENISDLKARLEKIIIGYNYQGEPVTAKDLKAGGALAALLK
DAIHPNLVQTLEHTPALIHGGPFANIAHGCNSVLATKLALKYGDYAVTEA
GFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRALKMHGGVPKADLATEN
VQAVVDGLPNLDKHLANIQDVYGLPVVVAINKFPLDTDAELQAVYDACDK
RGVDVVISDVWANGGAGGRELAEKVVTLAEQDNQFRFVYEEDDSIETKLT
KIVTKVYGGKGINLSSAAKRELADLERLGFGNYPICMAKTQYSFSDDAKK
LGAPTDFTVTISNLKVSAGAGFIVALTGAIMTMPGLPKVPASETIDIDEE
GNITGLF
>SPy1995 flaR, topology modulator
MKIAIIGHSGSGKSTLARFLGQHYHCEVFHLDQLHFSSNWQERSDHDMIA
DLSTCLLKQDLIIEGNYANCLYEERMSEADYIIYVNFSRFHCVYRAFKRY
LNYRGKTRPDMADNCQEKFDVAFVKWILLDGRSRNQLKKYQSVVQKYSHK
TIVLTNQKQLSHYMNTIN
>SPy1632 gmk, putative guanylate kinase
MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVD
GVDYFFRTREEFEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVF
LEIEVQGALQVKSKVPDGVFVFLTPPDLDELEDRLVGRGTDSQEVIAQRI
ERAKEEIALMREYDYAVVNDEVALAAERVKRIIETEHFRVERVIGRYDKM
IKITKNSFKAK
>SPy1204 guaA, putative GMP synthase
MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKITAQELR
EINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITHKLG
GKVVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPE
GFHLVGDSNDCPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISIC
GARGDWSMDNFIDMEIAKIRETVGDRKVLLGLSGGVDSSVVGVLLQKAIG
DQLTCIFVDHGLLRKDEGDQVMGMLGGKFGLNIIRVDASKRFLDLLADVE
DPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDIIESGTETAQTI
KSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEIVWRQPFPG
PGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVR
SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVD
HVNRIVYDITSKPPATVEWE
>SPy1730 hit, putative cell-cycle regulation histidine triad (HIT) protein
MENCIFCSIIQGDIPSSKVYEDEQVLAFLDISQTTKGHTLVIPKQHVRNL
LEMTAETASHLFARIPKIARAIQSATGATAMNIINNNEALAGQTVFHAHV
HLVPRYNEEDGISIQYTTHEPDFPVLEKLARQINQEVSS
>SPy2110 nrdD, putative anaerobic ribonucleoside-triphosphate reductase
MVSLEEDKVTVQPDIKVIKRDGRLVNFDSTKIYSALLKASMKVTRMSPLV
EAKLEAISDRIIAEIIERFPTNIKIYEIQNIVEHKLLAANEYAIAKEYIN
YRTQRDFARSQATDINFSIDKLINKDQTVVNENANKDSDVFNTQRDLTAG
IVGKSIGLKMLPSHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLA
NGFKIGNAEVESPKSIQTATAQISQIIANVASSQYGGCTADRIDEFLAPY
AELNFKKHMADAKKWIVETKRESYAFEKTQKDIYDAMQSLEYEINTLFTS
NGQTPFTSLGFGLGTSWFEREIQKAILTIRINGLGSEHRTAIFPKLIFTV
KRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIDLTGSFKSPMGC
RSFLQGWKDENGQDVTSGRMNLGVVTLNLPRIAMESNGDMDKFWELFNER
MLISKDALIYRVERVTEAKPANAPILYQYGAFGKRLEKTGNVNDLFKNRR
ATVSLGYIGLYEVASVFYGGQWEGNPDAKAFTLSIVKAMKQACEDWSDEY
GYHFSVYSTPSESLTDRFCRLDTEKFGIVTDITDKEYYTNSFHYDVRKSP
TPFEKLDFEKDYPEAGASGGFIHYCEYPVLQQNPKALEAVWDYAYDRVGY
LGTNTPIDKCYNCQFEGDFTPTERGFTCPNCGNNDPKTVDVVKRTCGYLG
NPQARPMVNGRHKEISARVKHMNGSTIKYPGL
>SPy0427 nrdE.1, ribonucleoside-diphosphate reductase, large chain
MSQTNASYLSLNALTRFKKPDGSYHFDSDKEAVRRYLEEHVSPNQMAFNS
LEDKLAYLINEGYYEQAIFDAYPNDLIKEAFHYAYQQGYRFLNLMGAMKF
YQSYALKTLDGKQYLETFEDRAVMNALFLADGDQTFVFDVIDAILHRRFQ
PATPTFLNAGKKRRGEYISCYLLRVEDNMESISRAISTSLQLSKRGGGVA
LCLTNLREIGAPIKGIENQATGIVPVMKLLEDSFSYANQLGQRQGAGAVY
LHAHHPEVLTFLDTKRENADEKIRIKSLALGLVIPDITFQLAKENKDMAL
FSPYDIKRAYGKDMSDISITEEYDKLLANPAIKKTYISARKFFQLIAELH
FESGYPYLLFDDTVNKRNPHAKKGRIVMSNLCSEIAQVSTPSTFKEDLSF
ETIGEDICCNLGSINIAQAMADAPHFEQLITTSIRALDRVSRVSDLNCAP
SVETGNAANHAVGLGAMNLHGFLATNHIYYDTKEAVDFTDLFFHAMAYYA
FKASCQLAKEKGAFAGFSLSTYSDGTYFAKYLQEDAKPQTAKVATLLQDY
GFTLPTVADWQALVADIKQFGLANAHLLAVAPTGSISYLSSCTPSLQPVV
APVEVRKEGSLGRIYVPAYQIDQANYAYYERGAYEVGPKAIIDVVAAAQK
HVDQAISLTLFMTDQATTRDLNRSYIQAFKQNCASIYYVRVRQDVLAGSE
QYDEDSLVTAPGASDETTTECQSCMI
>SPy1375 nrdE.2, putative ribonucleotide reductase alpha-chain
MSLKDLGDISYFRLNNEINRPVNGKIPLHKDKEALKAFSAENVLPNTMSF
TSITEKIEYLISNDYIESAFIQKYRPEFITELDSIIKSENFRFKSFMAAY
KFYQQYALKTNDGEHYLENLEDRVLFNALYFADGQEDLAKDLAVEMINQR
YQPATPSFLNAGRSRRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGG
VGITLSNLREAGAPIKGYAGAASGVVPVMKLFEDSFSYSNQLGQRQGAGV
VYLNVFHPDIIAFLSTKKENADEKVRVKTLSLGITVPDKFYELARKNEDM
YLFSPYNVEKEYGIPFNYLDITNMYDELVANPKITKTKIKARDLETEISK
LQQESGYPYIINIDTANKANPIDGKIIMSNLCSEILQVQTPSLINDAQEF
VEMGTDISCNLGSTNILNMMTSPDFGRSIKTMTRALTFVTDSSSIEAVPT
IKHGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLLNYWTL
VESNNIARERQTTFVGFENSKYANGSYFDKYVTGHFVPKSDLVKDLFKDH
FIPQASDWEALRDAVQKDGLYHQNRLAVAPNGSISYINDCSASIHPITQR
IEERQEKKIGKIYYPANGLSTDTIPYYTSAYDMDMRKVIDVYAAATEHVD
QGLSLTLFLRSELPMELYEWKTQSKQTTRDLSILRNYAFNKGIKSIYYIR
TFTDDGEEVGANQCESCVI
>SPy0425 nrdF.1, putative ribonucleotide reductase 2
MTQHYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRVTQNFWL
PEKVPVSNDLNSWRSLGEDWQQLITRTYTGLTLLDTVQATVGDVAQIQHS
QTDHEQVIYTNFAFMVGIHARSYGTIFSTLCSSEQIEEAHEWVVSTQSLQ
DRARVLIPYYTGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTS
DIIRLILRDKVIHNYYSGYKYQQKVARLSPEKQAEMKAFVFDLLYELIDL
EKAYLRELYAGFDLAEDAIRFSLYNAGKFLQNLGYESPFTDEETRVSPEV
FAQLSARADENHDFFSGNGSSYVMGITEETTDDDWEF
>SPy1378 nrdF.2, ribonucleotide diphosphate reductase small subunit
MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDWRKLSLQ
EKDLVGKVFGGLTLLDTMQSETGVEAIRADVRTPHEEAVLNNIQFMESVH
AKSYSSIFSTLNTKKEIEEIFEWTNNNEFLQEKARIINDIYANGDALQKK
VASTYLETFLFYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGY
KFQLGFNELPEDEQENFRDWMYDLLYQLYENEEKYTKTLYDGVGWTEEVM
TFLRYNANKALMNLGQDPLFPDTANDVNPIVMNGISTGTSNHDFFSQVGN
GYLLGSVEAMSDDDYNYGL
>SPy0426 nrdI, putative ribonucleotide reductase (NrdI protein)
MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYLLIVPTY
AAGGSDAKGAVSKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFALAGPII
SQKLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQTNNLITERT
HPCHKPMRHTSH
>SPy1868 nupC, putative nucleoside transporter
MQFIYSIIGILLVLGIVYAISFNRKSVSLSLIGKALIVQFIIALILVRIP
LGQQIVSVVSTGVTSVINCGQAGLNFVFGSLADSGAKTGFIFAIQTLGNI
VFLSALVSLLYYVGILGFVVKWIGKGVGKIMKSSEVESFVAVANMFLGQT
DSPILVSKYLGRMTDSEIMVVLVSGMGSMSVSILGGYIALGIPMEYLLIA
STMVPIGSILIAKILLPQTEPVQKIDDIKMDNKGNNANVIDAIAEGASTG
AQMAFSIGASLIAFVGLVSLINMMLSGLGIRLEQIFSYVFAPFGFLMGFD
HKNILLEGNLLGSKLILNEFVSFQQLGHLIKSLDYRTALVATISLCGFAN
LSSLGICVSGIAVLCPEKRSTLARLVFRAMIGGIAVSMLSAFIVGIVTLF
>SPy0447 pfs, putative MTA/SAH nucleosidase (5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase)
MKIGIIAAMEEELSLLLANLLDAQEHQVLSKTYYTGRFGKHELILVQSGV
GKVMSAMTVAILVEHFKAQAIINTGSAGAVASHLAIGDVVVADRLVYHDV
DATAFGYAYGQMAGQPLYYDCDPQFVAIFKQVLKHEKTNGQVGLIATGDS
FVAGQDKIDQIKTAFSDVLAVEMEGAAIAQAAHTAGKPFIVVRAMSDTAA
HDANITFDQFIIEAGKRSAQTLMTFLENLPV
>SPy1123 prs, putative phosphoribosyl pyrophosphate synthetase
MTERYADKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSNGEIMINI
EETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGY
SRQDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDN
LFTVPLFAERYSKLGLSGSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDY
AQDDSEREQGYIIGDVSGKKAILIDDILNTGKTFAEAAKILERSGATDTY
AVASHGLFAGGAADVLETAPIKEIIVTDSVKTKNRVPENVTYLSASDLIA
EAIIRIHERRPLSPLFSYQPKGKNNA
>SPy0020 prsA.2, putative ribose-phosphate pyrophosphokinase
MSYSDLKLFALSSNKELAEKVASAMGIQLGKSTVRQFSDGEIQVNIEESI
RGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQD
RKARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGA
PLIADYFDRHGLVGEDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSV
DKMNTSEVMNIIGNVSGKKCILIDDMIDTAGTICHAADALAEAGATAVYA
SCTHPVLSGPALDNIQRSAIEKLIVLDTIYLPKERLIDKIEQISIADLVA
EAIIRIHEKRPLSPLFEMGN
>SPy0892 punA, putative purine nucleoside phosphorylase
MSLMTKINETKDFLVTKGIETPEFGLILGSGLGELAEEVENAIVIDYADI
PNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVM
KALGCEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPR
FPDMSDAYTKVYRNKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFK
VLGADAVGMSTVPEVIVAAHSGLKVLGISAITNFAAGFQSELNHEEVVEV
TQHIKEDFKGLVKAILAEL
>SPy0160 purA, putative adenylosuccinate synthetase
MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIVIDGKKF
KLHLIPSGIFFPQKISVIGNGVVVNPKSLVKELAYLHDEGVTTDNLRISD
RAHVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADL
LDKDIFAERLRINLAEKNRLFEKMYDSTPLDFDAIFEEYYAYGQEIKQYV
TDTSVILNDALDAGKRVLFEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIG
SGVGPNKINKVVGVCKAYTSRVGDGPFPTELFDEVGERIREVGHEYGTTT
GRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVLSGLDTVKICVAYDLDG
KRIDYYPANLEQLKRCKPIYEELPGWQEDITGVRSLDELPENARNYVRRV
GELVGVRISTFSVGPGREQTNILESVWASI
>SPy0036 purB, adenylosuccinate lyase
MLERYSRPEMAAIWTEENKYHAWLEVEILADEAWAELGEIPKEDVAKIRE
KADFDIDRILEIEQDTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDT
AYGYLYKQANDIIRRDLENFTNIVADKAREHKMTIMMGRTHGVHAEPTTF
GLKLATWYSEMKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCD
KLGIRPQEISTQVLPRDLHAEYFAVLASIATSIERMATEIRGLQKSEQRE
VEEFFAKGQKGSSAMPHKRNPIGSENMTGLARVIRGHMVTAYENVSLWHE
RDISHSSAERIITPDTTILIDYMLNRFGNIVKNLTVFPENMMRNMESTFG
LIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPLLEEDTKVT
SCLTQEEIDELFNPIYYTKRVDDIFKRLGI
>SPy0024 purC, putative phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase)
MKTERKANNQVTNQLIYKGKAKDIYSTKDENVIRTVYKDQATMLNGARKE
TIDGKGALNNQISSLIFEKLNKAGVVTHYIEQISKNEQLNKKVDIIPLEV
VLRNVTAGSFSKRFGVEEGHVLETPIVEFYYKNDDLDDPFINDEHVKFLG
IVNDEEIAYLKGETRRINELLKGWFAQIGLNLIDFKLEFGFDQEGTIILA
DEFSPDNCRLWDKNGNHMDKDVFRRDLGNLTDVYQVVLEKLIAL
>SPy0032 purD, phosphoribosylamine-glycine ligase
MKLLVVGSGGREHAIAKKLLASKGVDQVFVAPGNDGMTLDGLDLVNIVVS
EHSRLIAFAKENEISWAFIGPDDALAAGIVDDFNSAGLRAFGPTKAAAEL
EWSKDFAKEIMVKYNVPTAAYGTFSDFEKAKAYIEEQGAPIVVKADGLAL
GKGVVVAETVEQAVEAAQEMLLDNKFGDSGARVVIEEFLDGEEFSLFAFA
NGDKFYIMPTAQDHKRAFDGDKGPNTGGMGAYAPVPHLPQSVVDTAVEMI
VRPVLEGMVAEGRPYLGVLYVGLILTADGPKVIEFNSRFGDPETQIILPR
LTSDFAQNIDDIMMGIEPYITWQKDGVTLGVVVASEGYPFDYEKGVPLPE
KTDGDIITYYAGVKFSENSELLLSNGGRVYMLVTTEDSVKAGQDKIYTQL
AQQDTTGLFYRNDIGSKAIRE
>SPy0033 purE, putative phosphoribosylaminoimidazole carboxylase I
MKTPIISIIMGSKSDWATMQKTAEVLDNFGIAYEKKVVSAHRTPDLMFKH
AEEARGRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSL
YSIVQMPGGVPVATMAIGEAGATNAALTALRILSIEDQNLADALAHFHEE
QGKIAEESSGELI
>SPy0026 purF, putative phosphoribosylpyrophosphate amidotransferase
MTYEVKSLNEECGVFGIWGHPQAAQVTYFGLHSLQHRGQEGAGIVSNDNG
KLYGYRNVGLLSEVFKNQSELDNLTGNAAIGHVRYATAGSADIRNIQPFL
YKFHDGQFALCHNGNLTNAISLRKELEKQGAIFNASSDTEILMHLIRRSH
NSSFMGKVKEALNTVKGGFAYLLMTENKLIAALDPNAFRPLSIGQMQNGA
WVISSETCAFEVVGAKWVRDVEPGEVILIDDRGIQCDRYTDETQLAICSM
EYVYFARPDSTIHGVNVHTARKNMGKRLAQEFKQDADIVIGVPNSSLSAA
MGFAEESGLPNEMGLVKNQYTQRTFIQPTQELREQGVRMKLSAVSGVVKG
KRVVMIDDSIVRGTTSRRIVGLLREAGASEVHVAIASPELKYPCFYGIDI
QTRRELISANHSVDEVCDIIGADSLTYLSLDGLIESIGLETKAPNGGLCV
AYFDGHYPTPLYDYEEEYLRSLEEKTSFYIQKVK
>SPy0034 purK, phosphoribosylaminoimidazole carboxylase II
MRNKEKSQRSQVVNSFKTIGIIGGGQLGQMMAIAAIYMGHKVITLDPASD
SPASRVSEVIVAPYDDVEALGQLAARCDVLTYEFENVDADGLDAVVSACQ
LPQGTDLLRISQNRIVEKDFLANKAGVTVAPYKVVTSSLDLGGLDLTKTY
VLKTETGGYDGHGQKIIRSAEDLPEAQQLANSAQCVLEEFVNFDLEISVI
VSGNGKDVTVFPVQENIHRNNILSKTIVPARISDQLADKAKKTAVQIAKK
LQLSGTLCVEMFTTADDIIVNEIAPRPHNSGRYSIEACDFSQFDTHILGV
LGAPLPQIQLHAPAVMLNVLGQHVQQATDYVAKNPSAHLHMYGKLEAKHN
RKMGHVTVFAKDADEVKEF
>SPy0027 purM, putative phosphoribosylformylglycinamide cyclo-ligase
MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFGGMFDLS
KTGVKEPVLVSGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAE
PLYFLDYIATGKNNPVKLEEVVSGVAEGCVQAGAALIGGETAEMPGMYGQ
DDYDLAGFAVGVAEKSQIIDGSKVKEGDILLGLASSGIHSNGYSLVRRVF
ADYTGKELLPELEGKQLKDVLLEPTRIYVKAALPLIKEELVKGIGHITGG
GFIENIPRMFADDLAAEIDEDKVPVLPIFKALEKYGDIKHEEMFEIFNMG
VGLMLAVSPENVNRVKELLDEPVYEIGRIIKKADASVVIK
>SPy0028 purN, Phosphoribosylglycinamide formyltransferase
MKIAVFASGNGSNFQVIAEQFPVSFVFSDHRDAYVLERAQNLAIPSFAFE
LKEFENKVAYEQAIVDLLDKHEIDLVCLAGYMKIVGETLLLAYERRIINI
HPAYLPEFPGAHGIEDAWEAGVDQSGVTIHWVDSGVDTGQVIQQVRVPRL
ADDSLESFETRIHETEYQLYPAVLDSLGVERKVI
>SPy0268 purR, putative purine operon repressor
MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDIAIIKKA
FEEANIGDIDTLTGASGGVIFTPSISETEARTIVEDLCQRLSESDRILPG
GYIYLSDLLSTPKILQNIGRIIANAFKGEKIDAVMTVATKGVPLANAVAN
ILSVPFVIVRRDLKITEGSTVSVNYASASSDRIEKMFLSKRSLKPNSRVL
IVDDFLKGGGTITGMISLLTEFDSTLVGVAVFAENAQSEREQMTFKSLLK
VSEIDVKNNNVVVEVGNIFDKWKKEREWT
>SPy0832 pyrB, putative aspartate transcarbamoylase
MSVVNNRVALTNLVSMEALTTEEVLGLINRGSEYKAGKVVISDHQKDLVA
NLFFENSTRTHKSFEVAEKKLGLTVLDFNADASAVNKGESLYDTVLTMSA
LGTDICVIRHPEDDYYKELVESPTITASIVNGGDGSGQHPSQCLLDLLTI
YEEFGRFEGLKIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEEWYSEA
FNAYGTYIAIDQIIKELDVLMLLRVQHERHDGHQSFSKEGYHQAFGLTQE
RYQQLKDSAIIMHPAPVNRDVEIADSLVEAPKARIVSQMANGVFVRMAII
EAILNGRNKNS
>SPy0907 pyrC, putative dihydroorotase
MILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVIDASGLI
VAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISD
VETLQEVLASAAKEKIHIYTNASVTQAFNGKDVTDFKALLEAGAVSFSDD
GIPLESSKVLKEAFDLANANQTFISLHEEDPQLNGVLGFNEGIAEEHFHF
CGATGVAEYSMIARDVMIAYDRQAHVHIQHLSKAESVQVVAFAQQLGAKV
TAEVSPQHFSTTEDLLLIAGTSAKMNPPLRTQRDRLAVIEGLKSGVITVI
ATDHAPHHKDEKTVDDMTKAPSGMTGLETSLSLGLTHLVEPGHLTLMSLL
EKMTLNPALLYGFDAGYLAENGPADLVIFADKQERLITENFASKASNSPF
IGNKLKGVVKYTIADGEVVYPN
>SPy1432 pyrD, putative dihydroorotate dehydrogenase
MVSTATQIGHFSFDNCLMNAAGVYCMTKEELMEVEKSQAASFVTKTGTLE
VRPGNPEPRYADTRLGSINSMGLPNNGFRYYLDFVSDLAKTGQHKPHFLS
VVGLSPTETETILKAIMASDYEGLVELNLSCPNVPGKPQIAYDFETTDQL
LENIFTYYTKPLGIKLPPYFDIVHFDQAAAIFNKYPLSFVNCVNSIGNGL
VIKDEQVLIKPKNGFGGIGGDYIKPTALANVHAFYKRLKPSIHIIGTGGV
KTGRDAFEHILCGASMVQIGTALHQEGPAIFERVTKELKTIMVEKGYQSL
DDFRGNLRYKD
>SPy0901 pyrE, putative orotate phosphoribosyltransferase
MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLSYPKTRD
LIENGFVETIKAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPK
DHGAGNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVA
IFTYELPKASQNFKEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKF
KEDQVNWQQ
>SPy0900 pyrF, putative orotidine-5'-decarboxylase PyrF
MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGPDIVRY
IKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAA
REGLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQL
DGAVCSAQEVEAIKAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRI
GSDYIVVGRPITQAKDPVAAYQAIKAEWAG
>SPy1894 pyrG, putative CTP synthetase
MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYINIDPGT
MSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLR
KERKGEYLGATVQVIPHITDALKEKIKRAASTTDSDVIITEVGGTVGDIE
SLPFLEALRQMKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELR
GLGIQPNMLVIRTEEPVEQGIKNKLAQFCDVNSEAVIESRDVEHLYQIPL
NLQAQSMDQIVCDHLKLNAPQADMTEWSAMVDKVMNLRKTTKIALVGKYV
ELPDAYLSVVEALKHSGYANDTAIDLKWVNANDVTVDNAADLLGDADGII
VPGGFGQRGTEGKIQAIRYARENDVPMLGICLGMQLTCVEFARHVLNMEG
ANSFELEPSTKYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKPGSKAAMAY
NNQEVVQRRHRHRYEFNNKFRPEFEAAGFVFSGVSPDNRLVEIVELKEKK
FFVAAQYHPELQSRPNRPEELYTAFVTAAIKNSN
>SPy0462 pyrH, putative uridylate kinase (UMP-kinase)
MEPKYQRILIKLSGEALAGEKGVGIDIPTVQAIAKEIAEVHVSGVQIALV
IGGGNLWRGEPAADAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRV
QTAIPMQNVAEPYIRGRALRHLEKNRIVVFGAGIGSPYFSTDTTAALRAA
EIEADAILMAKNGVDGVYNADPKKDANAVKFDELTHGEVIKRGLKIMDAT
ASTLSMDNDIDLVVFNMNEAGNIQRVVFGEHIGTTVSNKVCD
>SPy0831 pyrP, putative uracil permease
MKDVIYDVEEVPKAGMLVGLSFQHLFAMFGATVLVPILVGIDPSVALLSS
GLGTLAHLSVTKFKIPAYMGSSFAYIAAMQLLMKTNGIGAVAQGAMTGGL
VYLIVALIVKAIGNDWIDNILPPIVVGPIVMVIGLSLASTAVNDVMLKNG
NYNLTYLVIGLVTLLSVIFFNIYGKGIVAIVPLLLGLLVGYVVALLVGVL
TGQEIVDFTNVAQAKWFSIPSVEIPFLTYGVKFYPSAILTMAPIAFVTMT
EHFGHIMVLNSLTKRDYFKDPGLEKTLTGDGFAQIIAGFLGAPPVTSYGE
NIGVMALNKIFSVYVIAGAAVIAALLSFIGKVSALIQSIPTPVIGGISVA
LFGVIASSGLKILIESKVDMDNKKNLLIASVILVSGIGGLMLQVNGLQIS
GVAFSTLLGIILYQVLPEK
>SPy0830 pyrR, putative pyrimidine regulatory protein
MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVFLARRIQ
ERLHQLEGLDLPIGELDIKPFRDDMRVEEDTTLMSVDITGKDVILIDDVL
YTGRTIRAAIDNLVSLGRPARVSLAVLVDRGHRELPIRADYVGKNIPTSS
VEEIVVEVVEVDGRDRVSIIDST
>SPy1140 tdk2, putative thymidine kinase
MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRDGFGIVS
SRIGMRREAIPISNDMDIFTFIAQLEEKPYCVLIDESQFLSKQNVYDLAR
VVDELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKA
TMVLRTENGKPVYEGDQIQIGGNETYIPVCRKHYFNPDI
>SPy0882 thyA, putative thymidylate synthase
MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAFAEYDLA
KGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVD
QTRTIGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKG
LLPCAFQIMFDVRRVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMI
AKHFGWKIGKFFYFVNNLHIYDNQFDQAQELLKRQPVASQPKLVLNVPDR
TNFFDIKPDDFELQNYDPVKPQLHFDLAI
>SPy0399 tmk, putative thymidylate kinase
MITGKLITVEGPDGAGKTTVLEQLIPLLKQKVAQDILTTREPGGVAISEH
IRELILDINHTAMDPKTELLLYIAARRQHLVEKVLPALEAGQLVFIDRFI
DSSVAYQGAGRGLIKADIQWLNEFATDGLEPDLTLYFDVPSEIGLARINA
NQQREVNRLDLETIEIHQRVRKGYLALAKEHPKRIVTIDATKPLKEVVSV
ALEHVLALLLA
>SPy1368 udk, putative uridine kinase
MLKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYKDQSHMS
FEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTF
RQDPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMER
GRSLESIIDQYTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSK
IASILGEV
>SPy1869 udp, putative uridine phosphorylase
MQNYSGEVGLQYHLQIRPGDVGRYVIMPGDPKRCAKIAEHFDNAVLVADS
REYVTYTGTLNGEKVSVTSTGIGGPSASIAMEELKLCGADTFIRVGTCGG
IDLDVKGGDIVIATGAIRMEGTSKEYAPIEFPAVADLEVTNALVNAAKKL
GYTSHAGVVQCKDAFYGQHEPERMPVSYELLNKWEAWKRLGTKASEMESA
ALFVAASHLGVRCGSDFLVVGNQERNALGMDNPMAHDTEAAIQVAVEALR
TLIENDKSQ
>SPy0392 upp, putative uracil phosphoribosyltransferase
MGKCQVISHPLIQHKLSILRRQTTSTKDFRELVNEIAMLMGYEVSRDLPL
EDVDIQTPVSKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHI
GMYRNEETLEPVEYLVKLPEDINQRQIFLVDPMLATGGSAILAVDSLKKR
GAANIKFVCLVAAPEGVKKLQEAHPDIDIFTAALDDHLNEHGYIVPGLGD
AGDRLFGTK
>SPy1136 xpt, putative xanthine phosphoribosyltransferase
MQLLEERILTDGNILGENILKVDNFLTHQVDYRLMKAIGKVFAQKYAEAG
ITKVVTIEASGIAPAVYAAEAMDVPMIFAKKHKNITMTEGILTAEVYSFT
KQVTSTVSIAGKFLSKEDKVLIIDDFLANGQAAKGLIEIIGQAGAQVVGV
GIVIEKSFQDGRRLIEDMGIEVTSLARIKNFENGNLNFLEADA